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Articles published in Lancet

Retrieve available abstracts of 50 articles:
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Single Articles


    July 2026
  1. RUEL M, Nambala S, Guo MH, Verevkin A, et al
    Multivessel coronary artery bypass grafting via small thoracotomy versus sternotomy (MIST): an investigator-initiated, international, open-label, randomised controlled trial.
    Lancet. 2026 Jul 31:S0140-6736(26)01288-2. doi: 10.1016/S0140-6736(26)01288.
    PubMed     Abstract available


  2. SOTOMI Y, Kozuma K, Higuchi Y, Nakazawa G, et al
    1-month versus 12-month dual antithrombotic therapy after percutaneous coronary intervention in patients with atrial fibrillation (OPTIMA-AF): a multicentre, open-label, hybrid non-inferiority and superiority, randomised, controlled trial.
    Lancet. 2026 Jul 15:S0140-6736(26)00665-3. doi: 10.1016/S0140-6736(26)00665.
    PubMed     Abstract available


    June 2026
  3. HUANG H, Xu S, Qin T, Wang M, et al
    Efficacy and safety of tirofiban after successful endovascular reperfusion in acute ischaemic stroke (ATTRACTION) in China: a multicentre, double-blind, randomised controlled trial.
    Lancet. 2026 Jun 24:S0140-6736(26)00983-9. doi: 10.1016/S0140-6736(26)00983.
    PubMed     Abstract available


    May 2026
  4. SARRAJ A, Thomalla G, Yoshimura S, Huo X, et al
    Endovascular thrombectomy for patients with large-core ischaemic stroke presenting up to 24 h after onset (ATLAS): a systematic review and individual patient data meta-analysis with central imaging adjudication.
    Lancet. 2026 May 7:S0140-6736(26)00876-7. doi: 10.1016/S0140-6736(26)00876.
    PubMed     Abstract available


    April 2026
  5. HOLCK EN, Holm NR, Hildick-Smith D, Lindsay MM, et al
    Percutaneous coronary intervention versus coronary artery bypass grafting for unprotected left main stenosis: 10-year final results from the randomised, open-label, non-inferiority NOBLE trial.
    Lancet. 2026;407:1374-1382.
    PubMed     Abstract available


    March 2026
  6. DELEWI R, Aarts HM, Broeze GM, Hemelrijk KI, et al
    Deferral of percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation (PRO-TAVI): an investigator-initiated, multicentre, open-label, non-inferiority, randomised controlled trial.
    Lancet. 2026 Mar 29:S0140-6736(26)00308-9. doi: 10.1016/S0140-6736(26)00308.
    PubMed     Abstract available


  7. KANG J, Park S, Yang HM, Shin ES, et al
    Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention: 10-year follow-up of the HOST-EXAM trial.
    Lancet. 2026 Mar 29:S0140-6736(26)00422-8. doi: 10.1016/S0140-6736(26)00422.
    PubMed     Abstract available


  8. ZHU Y, Cheng Z, Zhao Y, Han L, et al
    Angiography-derived fractional flow reserve versus coronary angiography to guide coronary artery bypass grafting in patients undergoing surgical valve procedures with concomitant coronary artery disease in China (FAVOR IV-QVAS): a multicentre, triple-
    Lancet. 2026;407:1161-1170.
    PubMed     Abstract available


    January 2026
  9. ABIZAID A, Mehran R, Oliva A, Chamie D, et al
    Abluminus DES+ sirolimus-eluting stent versus everolimus-eluting stent in patients with diabetes and coronary artery disease (ABILITY Diabetes Global): results from a multicentre, randomised controlled trial.
    Lancet. 2026 Jan 8:S0140-6736(25)02157-9. doi: 10.1016/S0140-6736(25)02157.
    PubMed     Abstract available


    December 2025
  10. KEDHI E, Hermanides RS, Dambrink JE, Singh SK, et al
    TransCatheter aortic valve implantation and fractional flow reserve-guided percutaneous coronary intervention versus conventional surgical aortic valve replacement and coronary bypass grafting for treatment of patients with aortic valve stenosis and c
    Lancet. 2025;404:2593-2602.
    PubMed     Abstract available


    November 2025
  11. MEHTA SR, Tiong DTW, Bohm F, Ramasundarahettige C, et al
    Complete versus culprit lesion-only revascularisation for acute myocardial infarction (Complete Revascularisation Trialists' Collaboration): an individual patient data meta-analysis of randomised trials.
    Lancet. 2025 Nov 9:S0140-6736(25)02170-1. doi: 10.1016/S0140-6736(25)02170.
    PubMed     Abstract available


  12. KANG J, Park KW, Han JK, Hwang D, et al
    Dual antiplatelet therapy after percutaneous coronary intervention according to bleeding risk (HOST-BR): an open-label, multicentre, randomised clinical trial.
    Lancet. 2025;406:2244-2256.
    PubMed     Abstract available


    September 2025
  13. FALKENBERG M, James S, Andersson M, Andersson M, et al
    Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in chronic limb-threatening ischaemia (SWEDEPAD 1): a multicentre, participant-masked, registry-based, randomised controlled trial.
    Lancet. 2025;406:1103-1114.
    PubMed     Abstract available


  14. NORDANSTIG J, James S, Andersson M, Andersson M, et al
    Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in patients with intermittent claudication (SWEDEPAD 2): a multicentre, participant-masked, registry-based, randomised controlled trial.
    Lancet. 2025;406:1115-1127.
    PubMed     Abstract available


    August 2025
  15. KIM MC, Ahn JH, Hyun DY, Lim Y, et al
    Immediate versus staged complete revascularisation during index admission in patients with ST-segment elevation myocardial infarction and multivessel disease (OPTION-STEMI): a multicentre, non-inferiority, open-label, randomised trial.
    Lancet. 2025 Aug 28:S0140-6736(25)01529-6. doi: 10.1016/S0140-6736(25)01529.
    PubMed     Abstract available


  16. VERMA S, Leiter LA, Teoh H, Mancini GBJ, et al
    Effect of evolocumab on saphenous vein graft patency after coronary artery bypass surgery (NEWTON-CABG CardioLink-5): an international, randomised, double-blind, placebo-controlled trial.
    Lancet. 2025 Aug 28:S0140-6736(25)01633-2. doi: 10.1016/S0140-6736(25)01633.
    PubMed     Abstract available


    March 2025
  17. CHOI KH, Park YH, Lee JY, Jeong JO, et al
    Efficacy and safety of clopidogrel versus aspirin monotherapy in patients at high risk of subsequent cardiovascular event after percutaneous coronary intervention (SMART-CHOICE 3): a randomised, open-label, multicentre trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00449-0. doi: 10.1016/S0140-6736(25)00449.
    PubMed     Abstract available


  18. KIRTANE AJ, Genereux P, Lewis B, Shlofmitz RA, et al
    Orbital atherectomy versus balloon angioplasty before drug-eluting stent implantation in severely calcified lesions eligible for both treatment strategies (ECLIPSE): a multicentre, open-label, randomised trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00450-7. doi: 10.1016/S0140-6736(25)00450.
    PubMed     Abstract available


  19. FEARON WF, Zimmermann FM, Ding VY, Takahashi K, et al
    Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00505-7. doi: 10.1016/S0140-6736(25)00505.
    PubMed     Abstract available


  20. HU X, Zhang J, Yang S, Jiang J, et al
    Angiography-derived fractional flow reserve versus intravascular ultrasound to guide percutaneous coronary intervention in patients with coronary artery disease (FLAVOUR II): a multicentre, randomised, non-inferiority trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00504-5. doi: 10.1016/S0140-6736(25)00504.
    PubMed     Abstract available


    February 2025
  21. HILL MD, Goyal M, Demchuk AM, Menon BK, et al
    Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial.
    Lancet. 2025;405:560-570.
    PubMed     Abstract available


  22. LI W, Lan J, Wei M, Liu L, et al
    Normobaric hyperoxia combined with endovascular treatment for acute ischaemic stroke in China (OPENS-2 trial): a multicentre, randomised, single-blind, sham-controlled trial.
    Lancet. 2025;405:486-497.
    PubMed     Abstract available


    December 2024
  23. NOGUEIRA RG, Jovin TG, Liu X, Hu W, et al
    Endovascular therapy for acute vertebrobasilar occlusion (VERITAS): a systematic review and individual patient data meta-analysis.
    Lancet. 2024 Dec 11:S0140-6736(24)01820-8. doi: 10.1016/S0140-6736(24)01820.
    PubMed     Abstract available


    November 2024
  24. LIU J, Zhou Y, Zhang L, Li Z, et al
    Balloon guide catheters for endovascular thrombectomy in patients with acute ischaemic stroke due to large-vessel occlusion in China (PROTECT-MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial.
    Lancet. 2024 Nov 20:S0140-6736(24)02315-8. doi: 10.1016/S0140-6736(24)02315.
    PubMed     Abstract available


    October 2024
  25. ANDERSEN BK, Sejr-Hansen M, Maillard L, Campo G, et al
    Quantitative flow ratio versus fractional flow reserve for coronary revascularisation guidance (FAVOR III Europe): a multicentre, randomised, non-inferiority trial.
    Lancet. 2024 Oct 29:S0140-6736(24)02175-5. doi: 10.1016/S0140-6736(24)02175.
    PubMed     Abstract available


  26. ERLINGE D, Andersson J, Frobert O, Tornerud M, et al
    Bioadaptor implant versus contemporary drug-eluting stent in percutaneous coronary interventions in Sweden (INFINITY-SWEDEHEART): a single-blind, non-inferiority, registry-based, randomised controlled trial.
    Lancet. 2024 Oct 25:S0140-6736(24)02227-X. doi: 10.1016/S0140-6736(24)02227.
    PubMed     Abstract available


    September 2024
  27. NGUYEN TN, Abdalkader M, Fischer U, Qiu Z, et al
    Endovascular management of acute stroke.
    Lancet. 2024;404:1265-1278.
    PubMed     Abstract available


    August 2024
  28. VALGIMIGLI M, Hong SJ, Gragnano F, Chalkou K, et al
    De-escalation to ticagrelor monotherapy versus 12 months of dual antiplatelet therapy in patients with and without acute coronary syndromes: a systematic review and individual patient-level meta-analysis of randomised trials.
    Lancet. 2024 Aug 30:S0140-6736(24)01616-7. doi: 10.1016/S0140-6736(24)01616.
    PubMed     Abstract available


  29. HONG SJ, Lee SJ, Lee SH, Lee JY, et al
    Optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention for patients with complex lesions (OCCUPI): an investigator-initiated, multicentre, randomised, open-label, superiority trial in South Korea.
    Lancet. 2024 Aug 30:S0140-6736(24)01454-5. doi: 10.1016/S0140-6736(24)01454.
    PubMed     Abstract available


  30. MAMAS MA, Mintz GS
    Optical coherence tomography imaging for complex percutaneous coronary intervention.
    Lancet. 2024 Aug 30:S0140-6736(24)01593-9. doi: 10.1016/S0140-6736(24)01593.
    PubMed    


  31. GAO C, He X, Ouyang F, Zhang Z, et al
    Drug-coated balloon angioplasty with rescue stenting versus intended stenting for the treatment of patients with de novo coronary artery lesions (REC-CAGEFREE I): an open-label, randomised, non-inferiority trial.
    Lancet. 2024 Aug 30:S0140-6736(24)01594-0. doi: 10.1016/S0140-6736(24)01594.
    PubMed     Abstract available


  32. MCENTEGART MB, Kirtane AJ
    How feasible is a cage-free solution for de novo coronary artery disease?
    Lancet. 2024 Aug 30:S0140-6736(24)01696-9. doi: 10.1016/S0140-6736(24)01696.
    PubMed    


    May 2024
  33. HILKENS NA, Casolla B, Leung TW, de Leeuw FE, et al
    Stroke.
    Lancet. 2024 May 14:S0140-6736(24)00642-1. doi: 10.1016/S0140-6736(24)00642.
    PubMed     Abstract available


    April 2024
  34. FOLEY MJ, Rajkumar CA, Ahmed-Jushuf F, Simader FA, et al
    Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial.
    Lancet. 2024;403:1543-1553.
    PubMed     Abstract available


  35. LI X, Ge Z, Kan J, Anjum M, et al
    Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in acute coronary syndromes (IVUS-ACS): a two-stage, multicentre, randomised trial.
    Lancet. 2024 Apr 5:S0140-6736(24)00282-4. doi: 10.1016/S0140-6736(24)00282.
    PubMed     Abstract available


  36. DEN DEKKER WK
    Is intravascular imaging the future of percutaneous coronary intervention?
    Lancet. 2024 Apr 5:S0140-6736(24)00430-6. doi: 10.1016/S0140-6736(24)00430.
    PubMed    


  37. GE Z, Kan J, Gao X, Raza A, et al
    Ticagrelor alone versus ticagrelor plus aspirin from month 1 to month 12 after percutaneous coronary intervention in patients with acute coronary syndromes (ULTIMATE-DAPT): a randomised, placebo-controlled, double-blind clinical trial.
    Lancet. 2024 Apr 5:S0140-6736(24)00473-2. doi: 10.1016/S0140-6736(24)00473.
    PubMed     Abstract available


  38. PARK SJ, Ahn JM, Kang DY, Yun SC, et al
    Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trial.
    Lancet. 2024 Apr 4:S0140-6736(24)00413-6. doi: 10.1016/S0140-6736(24)00413.
    PubMed     Abstract available


  39. BOROVAC JA
    Percutaneous coronary intervention for non-obstructive vulnerable plaques.
    Lancet. 2024 Apr 4:S0140-6736(24)00488-4. doi: 10.1016/S0140-6736(24)00488.
    PubMed    


    February 2024
  40. LEE ZS, Ryan N
    Intravascular imaging in percutaneous coronary intervention.
    Lancet. 2024 Feb 21:S0140-6736(23)02686-7. doi: 10.1016/S0140-6736(23)02686.
    PubMed    


  41. STONE GW, Christiansen EH, Ali ZA, Andreasen LN, et al
    Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis.
    Lancet. 2024 Feb 21:S0140-6736(23)02454-6. doi: 10.1016/S0140-6736(23)02454.
    PubMed     Abstract available


  42. CONSOLI A, Gory B
    Long-term results of mechanical thrombectomy for large ischaemic stroke.
    Lancet. 2024 Feb 8:S0140-6736(24)00158-2. doi: 10.1016/S0140-6736(24)00158.
    PubMed    


  43. SARRAJ A, Abraham MG, Hassan AE, Blackburn S, et al
    Endovascular thrombectomy plus medical care versus medical care alone for large ischaemic stroke: 1-year outcomes of the SELECT2 trial.
    Lancet. 2024 Feb 8:S0140-6736(24)00050-3. doi: 10.1016/S0140-6736(24)00050.
    PubMed     Abstract available


    January 2024
  44. LANDI A, Pedrazzini G, Wild L, Beele A, et al
    Coronary embolisation of native aortic valve debris during transcatheter aortic valve replacement: mechanical embolectomy and histopathological analysis.
    Lancet. 2024;403:e5-e6.
    PubMed    


    December 2023
  45. JIMENEZ DIAZ VA, Iniguez Romo A
    Intracoronary artery visualisation of crystalline sirolimus deposits after drug-coated balloon angioplasty for acute coronary syndrome.
    Lancet. 2023;402:2111-2112.
    PubMed    


    October 2023
  46. IGLESIAS JF, Roffi M, Losdat S, Muller O, et al
    Long-term outcomes with biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in ST-segment elevation myocardial infarction: 5-year follow-up of the BIOSTEMI randomised superiority trial.
    Lancet. 2023 Oct 25:S0140-6736(23)02197-9. doi: 10.1016/S0140-6736(23)02197.
    PubMed     Abstract available


  47. BUITEN RA, Ploumen EH
    Drug-eluting stents for ST-segment elevation myocardial infarction: extending the biodegradable versus durable polymer debate.
    Lancet. 2023 Oct 25:S0140-6736(23)02297-3. doi: 10.1016/S0140-6736(23)02297.
    PubMed    


  48. DIPPEL DWJ, Roozenbeek B
    Thrombectomy for acute ischaemic stroke without advanced imaging.
    Lancet. 2023 Oct 10:S0140-6736(23)02229-8. doi: 10.1016/S0140-6736(23)02229.
    PubMed    


  49. BENDSZUS M, Fiehler J, Subtil F, Bonekamp S, et al
    Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial.
    Lancet. 2023 Oct 10:S0140-6736(23)02032-9. doi: 10.1016/S0140-6736(23)02032.
    PubMed     Abstract available


    August 2023
  50. HANKEY GJ
    Does thrombolysis add value to thrombectomy for acute ischaemic stroke?
    Lancet. 2023 Aug 25:S0140-6736(23)01202-3. doi: 10.1016/S0140-6736(23)01202.
    PubMed    


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