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  Stroke

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Articles published in Ann Intern Med

Retrieve available abstracts of 83 articles:
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Single Articles


    September 2025
  1. KOTANIDIS CP, Gorey S, Marwah H, Pearl A, et al
    Revision of Research Abstracts Through the Editorial Process.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-02250.
    PubMed    


  2. KHAN F, Hill MD
    In carotid stenosis with low or intermediate risk for stroke, adding revascularization to OMT did not improve outcomes at 2 y.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-03078.
    PubMed     Abstract available


  3. LO BM
    In acute ischemic stroke with large core infarct, EVT improves mRS scores but increases symptomatic intracranial hemorrhage at 90 d.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-03146.
    PubMed     Abstract available


  4. ALBERTS MJ
    In ischemic stroke prevention, apixaban and aspirin do not differ for intracranial hemorrhage events.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-03295.
    PubMed     Abstract available


  5. FIELD TS
    In AIS due to LVO presenting within 4.5 h of onset, adding tenecteplase to EVT increased functional independence at 90 d.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-03337.
    PubMed     Abstract available


    August 2025
  6. SMITH KC, Gaziano TA, Mushlin AI, Cutler DM, et al
    Effect of Systolic Blood Pressure Measurement Error on the Cost-Effectiveness of Intensive Blood Pressure Targets.
    Ann Intern Med. 2025 Aug 19. doi: 10.7326/ANNALS-25-00560.
    PubMed     Abstract available


  7. FIELD TS
    At 4.5 to 24 h after posterior circulation stroke onset, alteplase vs. standard medical care increased 90-d functional independence.
    Ann Intern Med. 2025 Aug 5. doi: 10.7326/ANNALS-25-02446.
    PubMed     Abstract available


    July 2025
  8. MONTANE B, Zhang S, Wolfe JD, Prime S, et al
    Catheter and Surgical Ablation for Atrial Fibrillation : A Systematic Review and Meta-analysis.
    Ann Intern Med. 2025 Jul 1. doi: 10.7326/ANNALS-25-00253.
    PubMed     Abstract available


    June 2025
  9. SAEED A, Mulukutla SR, Thoma F, Lemon L, et al
    Comparison of Semaglutide or Dulaglutide Versus Empagliflozin for Risk for Death and Cardiovascular Outcomes Among Patients With Type 2 Diabetes : Two Target Trial Emulation Studies.
    Ann Intern Med. 2025 Jun 17. doi: 10.7326/ANNALS-24-00775.
    PubMed     Abstract available


  10. KATSANOS AH, Douketis JD
    In survivors of ICH with AF, DOACs reduced incident ischemic stroke and increased recurrent ICH at a median 1.4 y.
    Ann Intern Med. 2025 Jun 3. doi: 10.7326/ANNALS-25-01772.
    PubMed     Abstract available


  11. BATUR P
    Some combined and progestin-only contraceptives were linked to increased risk for ischemic stroke and myocardial infarction.
    Ann Intern Med. 2025 Jun 3. doi: 10.7326/ANNALS-25-01774.
    PubMed     Abstract available


    May 2025
  12. ALBERTS MJ
    In patients with subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y in those with previous stroke or TIA.
    Ann Intern Med. 2025 May 6. doi: 10.7326/ANNALS-25-01330.
    PubMed     Abstract available


  13. LO B
    In ischemic stroke, IV thrombolysis >4.5 h after symptom onset vs. standard medical care improves 90-d functional outcomes.
    Ann Intern Med. 2025 May 6. doi: 10.7326/ANNALS-25-01326.
    PubMed     Abstract available


  14. MANSOOR H, Elgendy IY
    In AF with recent ACS or PCI, apixaban reduced total bleeding vs. VKA; aspirin increased total bleeding vs. placebo at 6 mo.
    Ann Intern Med. 2025;178:JC57.
    PubMed     Abstract available


  15. DONATO AA, Rahimian S
    Non-vitamin K oral anticoagulants and aspirin do not differ for major bleeding and intracranial hemorrhage at a mean 20 mo.
    Ann Intern Med. 2025;178:JC58.
    PubMed     Abstract available


    April 2025
  16. ABDEL-QADIR H, Gunn M, Fang J, Odugbemi T, et al
    Risk for Stroke After Newly Diagnosed Atrial Fibrillation During Hospitalization for Other Primary Diagnoses : A Retrospective Cohort Study.
    Ann Intern Med. 2025 Apr 22. doi: 10.7326/ANNALS-24-01967.
    PubMed     Abstract available


  17. YNALVEZ LA, Deswal A
    In adults with HF with preserved ejection fraction and obesity, tirzepatide reduced a composite of CV death or worsening HF at 2 y.
    Ann Intern Med. 2025;178:JC43.
    PubMed     Abstract available


  18. WANG Y, Lip GYH
    In HF with mildly reduced or preserved ejection fraction, finerenone reduced CV death and worsening HF, regardless of baseline LVEF.
    Ann Intern Med. 2025;178:JC44.
    PubMed     Abstract available


    February 2025
  19. LEE YJ, Gao X, Lee SH, Kan J, et al
    De-escalating Dual Antiplatelet Therapy to Ticagrelor Monotherapy in Acute Coronary Syndrome : A Systemic Review and Individual Patient Data Meta-Analysis of Randomized Clinical Trials.
    Ann Intern Med. 2025 Feb 18. doi: 10.7326/ANNALS-24-03102.
    PubMed     Abstract available


  20. SMETANA GW, Gelfand EV, Tung P, Burns RB, et al
    How Would You Manage This Patient With Recent-Onset Atrial Fibrillation? Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med. 2025 Feb 11. doi: 10.7326/ANNALS-24-03490.
    PubMed     Abstract available


  21. SHARMA M, Srivastava A
    In acute ischemic stroke with AF, early DOAC initiation was noninferior to delayed initiation for ischemic and hemorrhagic outcomes at 90 d.
    Ann Intern Med. 2025 Feb 4. doi: 10.7326/ANNALS-24-03879.
    PubMed     Abstract available


  22. KOROMPOKI E, Douketis JD
    In patients with ESUS, the effects of OAC and antiplatelet therapy on recurrent ischemic stroke differ across subgroups at 1 to 5 y.
    Ann Intern Med. 2025 Feb 4. doi: 10.7326/ANNALS-24-03608.
    PubMed     Abstract available


  23. RACO MD, Raco DL
    In asymptomatic severe AS, early TAVR vs. clinical surveillance reduced a composite of death, stroke, or CV hospitalization.
    Ann Intern Med. 2025 Feb 4. doi: 10.7326/ANNALS-24-03735.
    PubMed     Abstract available


    January 2025
  24. EAPEN BC, Tran J, Ballard-Hernandez J, Buelt A, et al
    Stroke Rehabilitation: Synopsis of the 2024 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines.
    Ann Intern Med. 2025 Jan 21. doi: 10.7326/ANNALS-24-02205.
    PubMed     Abstract available


  25. BATES ER
    In subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y, regardless of duration of recent subclinical AF episodes.
    Ann Intern Med. 2025 Jan 7. doi: 10.7326/ANNALS-24-03370.
    PubMed     Abstract available


  26. MORENO R
    In asymptomatic severe AS, early surgery vs. conservative therapy reduced a composite of death, MI, stroke, or HF hospitalization at 63 mo.
    Ann Intern Med. 2025 Jan 7. doi: 10.7326/ANNALS-24-03367.
    PubMed     Abstract available


    December 2024
  27. DONATO AA, Goswami V
    In acute ischemic stroke and a large infarct, adding EVT to medical treatment improved functional outcome at 12 mo.
    Ann Intern Med. 2024 Dec 3. doi: 10.7326/ANNALS-24-02886.
    PubMed     Abstract available


  28. LIBMAN H, Anderson TS, Rangan VV, Reynolds EE, et al
    How Would You Manage This Patient With Gastroesophageal Reflux Symptoms? Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med. 2024;177:1695-1701.
    PubMed     Abstract available


    November 2024
  29. ROMITI GF, Talerico G
    In subclinical AF, the benefit of apixaban vs. aspirin on stroke or systemic embolism trended higher with CHA(2)DS(2)-VASc >4.
    Ann Intern Med. 2024;177:JC125.
    PubMed     Abstract available


    October 2024
  30. WOODRUFF RC, Kaholokula JK, Riley L, Tong X, et al
    Cardiovascular Disease Mortality Among Native Hawaiian and Pacific Islander Adults Aged 35 Years or Older, 2018 to 2022.
    Ann Intern Med. 2024 Oct 15. doi: 10.7326/M24-0801.
    PubMed     Abstract available


  31. SHARMA M, Srivastva A
    In ischemic stroke treated within 4.5 h, reteplase vs. alteplase increased excellent functional outcome at 90 d.
    Ann Intern Med. 2024 Oct 1. doi: 10.7326/ANNALS-24-02228.
    PubMed     Abstract available


  32. DAVIDSON MB
    In adults with hypertension and high CV risk, intensive vs. standard BP-lowering therapy reduced major vascular events.
    Ann Intern Med. 2024;177:JC111.
    PubMed     Abstract available


    September 2024
  33. KODUMURI N, Siddu M, Jillella D
    In acute ischemic stroke with a large core infarct, endovascular thrombectomy reduced disability at 90 d.
    Ann Intern Med. 2024 Sep 3. doi: 10.7326/ANNALS-24-01578.
    PubMed     Abstract available


    August 2024
  34. DUNBAR KB
    Gastroesophageal Reflux Disease.
    Ann Intern Med. 2024;177:ITC113-ITC128.
    PubMed     Abstract available


  35. CLIFFORD C, Yan AT
    After PCI and 1 mo of DAPT for ACS, ticagrelor alone vs. continued DAPT for 11 mo reduced bleeding without increasing MACCE.
    Ann Intern Med. 2024;177:JC86.
    PubMed     Abstract available


    July 2024
  36. SIMON TG, Singer DE, Zhang Y, Mastrorilli JM, et al
    Comparative Effectiveness and Safety of Apixaban, Rivaroxaban, and Warfarin in Patients With Cirrhosis and Atrial Fibrillation : A Nationwide Cohort Study.
    Ann Intern Med. 2024 Jul 9. doi: 10.7326/M23-3067.
    PubMed     Abstract available


  37. BARNES GD
    In device-detected AF, DOACs vs. aspirin or placebo reduce ischemic stroke and increase major bleeding.
    Ann Intern Med. 2024 Jul 2. doi: 10.7326/ANNALS-24-00652.
    PubMed     Abstract available


    June 2024
  38. SEBASTIAN IA, Hill MD
    In ischemic stroke, adding IV thrombolysis
    Ann Intern Med. 2024 Jun 4. doi: 10.7326/ANNALS-24-00519.
    PubMed     Abstract available


  39. WEITZ HH, Merli GJ, Lip GYH
    Annals Consult Guys - The ABCs of Atrial Fibrillation.
    Ann Intern Med. 2024;177:e2400618CG.
    PubMed    


  40. FIELD TS
    In cryptogenic stroke and atrial cardiopathy, apixaban did not reduce recurrent stroke vs. aspirin.
    Ann Intern Med. 2024;177:JC65.
    PubMed     Abstract available


  41. CHIA JE, Mukherjee D
    After stent implantation for ACS, ticagrelor monotherapy after <1 mo of DAPT vs. 12 mo of DAPT improved 1-y net clinical benefit.
    Ann Intern Med. 2024;177:JC64.
    PubMed     Abstract available


    May 2024
  42. XU W, Lee AL, Lam CLK, Danaei G, et al
    Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults : Real-World Evidence From a Target Trial Emulation Study.
    Ann Intern Med. 2024 May 28. doi: 10.7326/M24-0004.
    PubMed     Abstract available


  43. ALBERTS MJ
    In mild ischemic stroke or high-risk TIA, DAPT started
    Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0029.
    PubMed     Abstract available


  44. LI XRC
    Web Exclusive. Annals Graphic Medicine - Life After a Stroke.
    Ann Intern Med. 2024;177:eG230020.
    PubMed    


  45. DUNN A
    In older patients with AF and frailty, switching from VKA to NOAC therapy increased a composite of major or CRNM bleeding at 12 mo.
    Ann Intern Med. 2024;177:JC57.
    PubMed     Abstract available


    April 2024
  46. DRAKE T, Landsteiner A, Langsetmo L, MacDonald R, et al
    Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Systematic Review and Network Meta-analysis for the American College of Physicians.
    Ann Intern Med. 2024 Apr 19. doi: 10.7326/M23-1490.
    PubMed     Abstract available


  47. QASEEM A, Obley AJ, Shamliyan T, Hicks LA, et al
    Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Clinical Guideline From the American College of Physicians.
    Ann Intern Med. 2024 Apr 19. doi: 10.7326/M23-2788.
    PubMed     Abstract available


  48. AJZENBERG H, Binhashr MAN, Hewitt MK, Unger M, et al
    Critical Care: What You May Have Missed in 2023.
    Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0565.
    PubMed     Abstract available


    March 2024
  49. SHADRIN IY, Newby LK
    In subclinical AF, apixaban reduced stroke or systemic embolism but increased major bleeding vs. aspirin at 3.5 y.
    Ann Intern Med. 2024;177:JC26.
    PubMed     Abstract available


    February 2024
  50. KANJEE Z, Dearborn-Tomazos JL, Kumar S, Reynolds EE, et al
    How Would You Prevent Subsequent Strokes in This Patient? Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med. 2024 Feb 13. doi: 10.7326/M23-3136.
    PubMed     Abstract available


    January 2024
  51. FU EL, Carrero JJ, Sang Y, Evans M, et al
    Association of Low Glomerular Filtration Rate With Adverse Outcomes at Older Age in a Large Population With Routinely Measured Cystatin C.
    Ann Intern Med. 2024 Jan 30. doi: 10.7326/M23-1138.
    PubMed     Abstract available


  52. HILL MD
    After EVT for ischemic stroke, intensive vs. conventional BP management reduced functional independence at 3 mo.
    Ann Intern Med. 2024 Jan 2. doi: 10.7326/J23-0106.
    PubMed     Abstract available


    December 2023
  53. SUD M, Sivaswamy A, Austin PC, Anderson TJ, et al
    Development and Validation of the CANHEART Population-Based Laboratory Prediction Models for Atherosclerotic Cardiovascular Disease.
    Ann Intern Med. 2023 Dec 12. doi: 10.7326/M23-1345.
    PubMed     Abstract available


  54. AGARWAL R, Tu W, Farjat AE, Farag YMK, et al
    Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis.
    Ann Intern Med. 2023 Dec 5. doi: 10.7326/M23-1023.
    PubMed     Abstract available


  55. WEITZ HH, Merli GJ, Benesch C
    Annals Consult Guys - Surgery After Thromboembolic Stroke.
    Ann Intern Med. 2023;176:eW220025.
    PubMed    


    November 2023
  56. TANG M, Nakamoto CH, Stern AD, Zubizarreta JR, et al
    Effects of Remote Patient Monitoring Use on Care Outcomes Among Medicare Patients With Hypertension : An Observational Study.
    Ann Intern Med. 2023 Nov 7. doi: 10.7326/M23-1182.
    PubMed     Abstract available


  57. CRUZ-FLORES S
    In healthy older adults, low-dose aspirin did not differ from placebo for ischemic stroke but increased intracranial bleeding.
    Ann Intern Med. 2023 Nov 7. doi: 10.7326/J23-0092.
    PubMed     Abstract available


  58. TANNU M, Newby LK
    In CAD, P2Y12 inhibitor vs. aspirin monotherapy reduces a composite CV outcome without increasing major bleeding.
    Ann Intern Med. 2023;176:JC123.
    PubMed     Abstract available


    October 2023
  59. EASTIN C
    In minor, nondisabling, acute ischemic stroke, DAPT was noninferior to IV alteplase for excellent functional outcome at 90 d.
    Ann Intern Med. 2023 Oct 3. doi: 10.7326/J23-0072.
    PubMed     Abstract available


  60. ALBERTS MJ
    In ischemic stroke without large or medium vessel occlusion, tirofiban increased likelihood of an excellent outcome.
    Ann Intern Med. 2023 Oct 3. doi: 10.7326/J23-0074.
    PubMed     Abstract available


    September 2023
  61. RIETZ H, Pennlert J, Nordstrom P, Brunstrom M, et al
    Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events : A Cohort Study.
    Ann Intern Med. 2023 Sep 26. doi: 10.7326/M23-0112.
    PubMed     Abstract available


  62. KIM DH, Lee SB, Park CM, Levin R, et al
    Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study.
    Ann Intern Med. 2023 Sep 5. doi: 10.7326/M22-3021.
    PubMed     Abstract available


  63. BANNOW BTS
    In adults with cancer and VTE, DOACs were noninferior to LMWH for recurrent, nonfatal VTE at 6 mo.
    Ann Intern Med. 2023;176:JC104.
    PubMed     Abstract available


    August 2023
  64. CARLIN S, Douketis J
    In AF, the effects of DOACs vs. warfarin on death and stroke/systemic embolism vary by baseline CrCl level.
    Ann Intern Med. 2023 Aug 1. doi: 10.7326/J23-0054.
    PubMed     Abstract available


  65. BAHREINI M, Lang E
    In ischemic stroke, EVT improved 90-d function more than usual care across admission SBP levels.
    Ann Intern Med. 2023 Aug 1. doi: 10.7326/J23-0055.
    PubMed     Abstract available


  66. KIRSCHNER JM, Hunter BR
    SAEM issued 4 strong recommendations (high-certainty evidence) for determining cause of acute vestibular syndrome in the ED.
    Ann Intern Med. 2023;176:JC86.
    PubMed     Abstract available


    July 2023
  67. MCCORMICK N, Yokose C, Wei J, Lu N, et al
    Comparative Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and Hospitalizations : A General Population Cohort Study.
    Ann Intern Med. 2023 Jul 25. doi: 10.7326/M23-0724.
    PubMed     Abstract available


  68. ESKIN B
    In ischemic stroke, adding EVT to usual care at 6 to 24 h improved functional status at 90 d.
    Ann Intern Med. 2023 Jul 4. doi: 10.7326/J23-0050.
    PubMed     Abstract available


  69. AL-KHATIB SM
    Atrial Fibrillation.
    Ann Intern Med. 2023;176:ITC97-ITC112.
    PubMed     Abstract available


    June 2023
  70. FERGUSON E, Lang E
    In large acute ischemic stroke, adding endovascular thrombectomy to medical therapy improved function at 90 d.
    Ann Intern Med. 2023 Jun 6. doi: 10.7326/J23-0033.
    PubMed     Abstract available


  71. ALBERTS MJ
    After ICH, starting long-term therapeutic oral anticoagulation in patients with AF reduces MACE at 1 to 3 y.
    Ann Intern Med. 2023;176:JC71.
    PubMed     Abstract available


    May 2023
  72. RAY WA, Chung CP, Stein CM, Smalley W, et al
    Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study.
    Ann Intern Med. 2023 May 23. doi: 10.7326/M22-3238.
    PubMed     Abstract available


  73. RICHARDSON TL JR, Halvorson AE, Hackstadt AJ, Hung AM, et al
    Primary Occurrence of Cardiovascular Events After Adding Sodium-Glucose Cotransporter-2 Inhibitors or Glucagon-like Peptide-1 Receptor Agonists Compared With Dipeptidyl Peptidase-4 Inhibitors: A Cohort Study in Veterans With Diabetes.
    Ann Intern Med. 2023 May 9. doi: 10.7326/M22-2751.
    PubMed     Abstract available


  74. ZHU J, Kamel H, Gupta A, Mushlin AI, et al
    Prioritizing Quality Measures in Acute Stroke Care : A Cost-Effectiveness Analysis.
    Ann Intern Med. 2023 May 2. doi: 10.7326/M22-3186.
    PubMed     Abstract available


  75. GRIFFIN M, Lip GYH
    In limb or pelvic fracture, aspirin was noninferior to enoxaparin for reducing all-cause death.
    Ann Intern Med. 2023;176:JC56.
    PubMed     Abstract available


    April 2023
  76. MARCUCCI M, Painter TW, Conen D, Lomivorotov V, et al
    Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery : An International Randomized Controlled Trial.
    Ann Intern Med. 2023 Apr 25. doi: 10.7326/M22-3157.
    PubMed     Abstract available


  77. ADIE SK, Konerman MC
    Annals for Hospitalists Inpatient Notes - Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure With Preserved Ejection Fraction-What Hospitalists Need to Know.
    Ann Intern Med. 2023;176:eM230588.
    PubMed    


  78. LADER EW
    After PCI and 6 to 18 mo of DAPT, clopidogrel reduced a composite of clinical events vs. aspirin at 6 y.
    Ann Intern Med. 2023;176:JC38.
    PubMed     Abstract available


  79. PERISETTI A, Sharma P
    In older patients receiving aspirin, H pylori eradication reduced hospitalization or death due to peptic ulcer bleeding at 2.5 y.
    Ann Intern Med. 2023;176:JC45.
    PubMed     Abstract available


    March 2023
  80. FORD ND, DeSisto CL, Galang RR, Kuklina EV, et al
    Cardiac Arrest During Delivery Hospitalization : A Cohort Study.
    Ann Intern Med. 2023 Mar 14. doi: 10.7326/M22-2750.
    PubMed     Abstract available


  81. CHEW DS, Piccini JP
    Left Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation.
    Ann Intern Med. 2023;176:eL220517.
    PubMed    


  82. ANDERSON CE, Lieberman RA, Olshansky B
    Left Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation.
    Ann Intern Med. 2023;176:eL220516.
    PubMed    


  83. DUNN A
    In AF, underdosing of DOACs was not linked to reduced bleeding.
    Ann Intern Med. 2023;176:JC32.
    PubMed     Abstract available


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