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Articles published in Proc Natl Acad Sci U S A

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    July 2021

  1. Correction for Canher et al., Rocks in the auxin stream: Wound-induced auxin accumulation and ERF115 expression synergistically drive stem cell regeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  2. AL TANOURY Z, Zimmerman JF, Rao J, Sieiro D, et al
    Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell-derived skeletal muscle in vitro.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  3. DEUSE T, Tediashvili G, Hu X, Gravina A, et al
    Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  4. VENNEKENS A, Laporte E, Hermans F, Cox B, et al
    Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  5. MORVAN MG, Teque F, Ye L, Moreno ME, et al
    Genetically edited CD34(+) cells derived from human iPS cells in vivo but not in vitro engraft and differentiate into HIV-resistant cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  6. SCHAFER ST, Gage FH
    To eat, or not to eat, that is the question: Neural stem cells escape phagocytosis in autism with macrocephaly.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    April 2021
  7. LE MERCIER A, Bonnavion R, Yu W, Alnouri MW, et al
    GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  8. CHAN A, Ma S, Pearson BJ, Chan D, et al
    Collagen IV differentially regulates planarian stem cell potency and lineage progression.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  9. ZHAO L, Gao X, Zheng Y, Wang Z, et al
    Establishment of bovine expanded potential stem cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  10. SARDI J, Bener MB, Simao T, Descoteaux AE, et al
    Mad dephosphorylation at the nuclear pore is essential for asymmetric stem cell division.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  11. JU JM, Nam G, Lee YK, Jung M, et al
    IDO1 scavenges reactive oxygen species in myeloid-derived suppressor cells to prevent graft-versus-host disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  12. PITUCH KC, Zannikou M, Ilut L, Xiao T, et al
    Neural stem cells secreting bispecific T cell engager to induce selective antiglioma activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  13. LU TM, Houghton S, Magdeldin T, Duran JGB, et al
    Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  14. MONCHO-AMOR V, Chakravarty P, Galichet C, Matheu A, et al
    SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  15. HANEMAAIJER ES, Margaritis T, Sanders K, Bos FL, et al
    Single-cell atlas of developing murine adrenal gland reveals relation of Schwann cell precursor signature to neuroblastoma phenotype.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  16. SCHREIBER C, Amiri B, Heyn JCJ, Radler JO, et al
    On the adhesion-velocity relation and length adaptation of motile cells on stepped fibronectin lanes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  17. MURAKAMI K, Terakado Y, Saito K, Jomen Y, et al
    A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  18. SHIN B, Hosokawa H, Romero-Wolf M, Zhou W, et al
    Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  19. MOROZKO EL, Smith-Geater C, Monteys AM, Pradhan S, et al
    PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  20. STIRPARO GG, Kurowski A, Yanagida A, Bates LE, et al
    OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  21. CUI L, Moraga I, Lerbs T, Van Neste C, et al
    Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  22. UEBBING S, Gockley J, Reilly SK, Kocher AA, et al
    Massively parallel discovery of human-specific substitutions that alter enhancer activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  23. MASET A, Galla L, Francia S, Cozzolino O, et al
    Altered Cl(-) homeostasis hinders forebrain GABAergic interneuron migration in a mouse model of intellectual disability.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  24. FAN C, Zhao C, Zhang F, Kesarwani M, et al
    Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  25. ISHII S, Sasaki T, Mohammad S, Hwang H, et al
    Primary cilia safeguard cortical neurons in neonatal mouse forebrain from environmental stress-induced dendritic degeneration.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  26. COPELAND J, Simoes-Costa M
    Post-transcriptional tuning of FGF signaling mediates neural crest induction.
    Proc Natl Acad Sci U S A. 2020;117:33305-33316.
    PubMed     Abstract available


  27. GAO Y, Chen X, He Q, Gimple RC, et al
    Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin.
    Proc Natl Acad Sci U S A. 2020;117:33295-33304.
    PubMed     Abstract available


  28. YANG L, Jama B, Wang H, Labarta-Bajo L, et al
    TCRalpha reporter mice reveal contribution of dual TCRalpha expression to T cell repertoire and function.
    Proc Natl Acad Sci U S A. 2020;117:32574-32583.
    PubMed     Abstract available


  29. LIU H, Zhang Y, Zhang YY, Li YP, et al
    Human embryonic stem cell-derived organoid retinoblastoma reveals a cancerous origin.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2011780117.
    PubMed     Abstract available


  30. SATTERLEE JW, Strable J, Scanlon MJ
    Plant stem-cell organization and differentiation at single-cell resolution.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2018788117.
    PubMed     Abstract available


  31. DONG A, Preusch CB, So WK, Lin K, et al
    A long noncoding RNA, LncMyoD, modulates chromatin accessibility to regulate muscle stem cell myogenic lineage progression.
    Proc Natl Acad Sci U S A. 2020 Dec 8. pii: 2005868117.
    PubMed     Abstract available


  32. WANG QW, Lu SY, Liu YN, Chen Y, et al
    Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity.
    Proc Natl Acad Sci U S A. 2020;117:31438-31447.
    PubMed     Abstract available


  33. ASLAM MA, Alemdehy MF, Hao B, Krijger PHL, et al
    The Ig heavy chain protein but not its message controls early B cell development.
    Proc Natl Acad Sci U S A. 2020;117:31343-31352.
    PubMed     Abstract available


  34. GUDMUNDSSON KO, Nguyen N, Oakley K, Han Y, et al
    Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence.
    Proc Natl Acad Sci U S A. 2020 Dec 2. pii: 2017626117.
    PubMed     Abstract available


    November 2020
  35. XIE XP, Laks DR, Sun D, Poran A, et al
    High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2014389117.
    PubMed     Abstract available


  36. TANG S, Zhang M, Zeng S, Huang Y, et al
    Reversal of autoimmunity by mixed chimerism enables reactivation of beta cells and transdifferentiation of alpha cells in diabetic NOD mice.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2012389117.
    PubMed     Abstract available


  37. LEE JP, Zhang R, Yan M, Duggineni S, et al
    Chemical mutagenesis of a GPCR ligand: Detoxifying "inflammo-attraction" to direct therapeutic stem cell migration.
    Proc Natl Acad Sci U S A. 2020 Nov 20. pii: 1911444117.
    PubMed     Abstract available


  38. ZHANG T, Periz G, Lu YN, Wang J, et al
    USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway.
    Proc Natl Acad Sci U S A. 2020;117:28114-28125.
    PubMed     Abstract available


  39. LIN RJ, Kuo MW, Yang BC, Tsai HH, et al
    B3GALT5 knockout alters gycosphingolipid profile and facilitates transition to human naive pluripotency.
    Proc Natl Acad Sci U S A. 2020;117:27435-27444.
    PubMed     Abstract available


  40. CAO K, Ugarenko M, Ozark PA, Wang J, et al
    DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation.
    Proc Natl Acad Sci U S A. 2020;117:27365-27373.
    PubMed     Abstract available


  41. JAIN SU, Khazaei S, Marchione DM, Lundgren SM, et al
    Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.
    Proc Natl Acad Sci U S A. 2020;117:27354-27364.
    PubMed     Abstract available


  42. ROSENBLOOM AB, Tarczynski M, Lam N, Kane RS, et al
    beta-Catenin signaling dynamics regulate cell fate in differentiating neural stem cells.
    Proc Natl Acad Sci U S A. 2020 Nov 2. pii: 2008509117.
    PubMed     Abstract available


    October 2020
  43. GROLMAN JM, Weinand P, Mooney DJ
    Extracellular matrix plasticity as a driver of cell spreading.
    Proc Natl Acad Sci U S A. 2020;117:25999-26007.
    PubMed     Abstract available


  44. ZHANG L, Jing H, Li H, Chen W, et al
    Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling.
    Proc Natl Acad Sci U S A. 2020;117:26448-26459.
    PubMed     Abstract available


    September 2020
  45. HSU J, Huang HT, Lee CT, Choudhuri A, et al
    CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation.
    Proc Natl Acad Sci U S A. 2020;117:23626-23635.
    PubMed     Abstract available


  46. KRENN PW, Koschmieder S, Fassler R
    Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches.
    Proc Natl Acad Sci U S A. 2020 Sep 14. pii: 2009078117.
    PubMed     Abstract available


  47. CICCARELLI M, Giassetti MI, Miao D, Oatley MJ, et al
    Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males.
    Proc Natl Acad Sci U S A. 2020 Sep 14. pii: 2010102117.
    PubMed     Abstract available


  48. HE Z, An S, Chen J, Zhang S, et al
    Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
    Proc Natl Acad Sci U S A. 2020 Sep 9. pii: 2007773117.
    PubMed     Abstract available


  49. SOOD S, Weber CM, Hodges HC, Krokhotin A, et al
    CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation.
    Proc Natl Acad Sci U S A. 2020;117:22331-22340.
    PubMed     Abstract available


  50. YIN Y, Cao S, Fu H, Fan X, et al
    A noncanonical role of NOD-like receptor NLRP14 in PGCLC differentiation and spermatogenesis.
    Proc Natl Acad Sci U S A. 2020;117:22237-22248.
    PubMed     Abstract available


  51. HUANG D, Abbott RK, Havenar-Daughton C, Skog PD, et al
    B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.
    Proc Natl Acad Sci U S A. 2020 Sep 1. pii: 2004489117.
    PubMed     Abstract available


  52. KILLAARS AR, Walker CJ, Anseth KS
    Nuclear mechanosensing controls MSC osteogenic potential through HDAC epigenetic remodeling.
    Proc Natl Acad Sci U S A. 2020;117:21258-21266.
    PubMed     Abstract available


  53. LJUNGGREN-ROSE A, Natarajan C, Matta P, Pandey A, et al
    Anacardic acid induces IL-33 and promotes remyelination in CNS.
    Proc Natl Acad Sci U S A. 2020;117:21527-21535.
    PubMed     Abstract available


    August 2020
  54. WHITE CW 3RD, Fan X, Maynard JC, Wheatley EG, et al
    Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.
    Proc Natl Acad Sci U S A. 2020 Aug 26. pii: 2007439117.
    PubMed     Abstract available


  55. VIETRI RUDAN M, Mishra A, Klose C, Eggert US, et al
    Human epidermal stem cell differentiation is modulated by specific lipid subspecies.
    Proc Natl Acad Sci U S A. 2020 Aug 25. pii: 2011310117.
    PubMed     Abstract available


  56. WANG X, Sathe AA, Smith GR, Ruf-Zamojski F, et al
    Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages.
    Proc Natl Acad Sci U S A. 2020;117:20729-20740.
    PubMed     Abstract available


  57. SANGOKOYA C, Blelloch R
    MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis.
    Proc Natl Acad Sci U S A. 2020;117:20625-20635.
    PubMed     Abstract available


  58. SU YH, Zhou C, Li YJ, Yu Y, et al
    Integration of pluripotency pathways regulates stem cell maintenance in the Arabidopsis shoot meristem.
    Proc Natl Acad Sci U S A. 2020 Aug 24. pii: 2015248117.
    PubMed     Abstract available


  59. ROUDNICKY F, Zhang JD, Kim BK, Pandya NJ, et al
    Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells.
    Proc Natl Acad Sci U S A. 2020;117:19854-19865.
    PubMed     Abstract available


  60. SCHMIDERER L, Subramaniam A, Zemaitis K, Backstrom A, et al
    Efficient and nontoxic biomolecule delivery to primary human hematopoietic stem cells using nanostraws.
    Proc Natl Acad Sci U S A. 2020 Aug 17. pii: 2001367117.
    PubMed     Abstract available


  61. LEE CM, Zhou L, Liu J, Shi J, et al
    Single-cell RNA-seq analysis revealed long-lasting adverse effects of tamoxifen on neurogenesis in prenatal and adult brains.
    Proc Natl Acad Sci U S A. 2020;117:19578-19589.
    PubMed     Abstract available


  62. BERNSTEIN SL, Guo Y, Kerr C, Fawcett RJ, et al
    The optic nerve lamina region is a neural progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020;117:19287-19298.
    PubMed     Abstract available


  63. LIU J, Huang ZP, Nie M, Wang G, et al
    Regulation of myonuclear positioning and muscle function by the skeletal muscle-specific CIP protein.
    Proc Natl Acad Sci U S A. 2020;117:19254-19265.
    PubMed     Abstract available


  64. SUSANTO E, Marin Navarro A, Zhou L, Sundstrom A, et al
    Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells.
    Proc Natl Acad Sci U S A. 2020 Aug 3. pii: 1920521117.
    PubMed     Abstract available


    July 2020
  65. DE LA VEGA GALLARDO N, Penalva R, Dittmer M, Naughton M, et al
    Dynamic CCN3 expression in the murine CNS does not confer essential roles in myelination or remyelination.
    Proc Natl Acad Sci U S A. 2020;117:18018-18028.
    PubMed     Abstract available


  66. PHAN QT, Tan WH, Liu R, Sundaram S, et al
    Cxcl9l and Cxcr3.2 regulate recruitment of osteoclast progenitors to bone matrix in a medaka osteoporosis model.
    Proc Natl Acad Sci U S A. 2020 Jul 27. pii: 2006093117.
    PubMed     Abstract available


  67. THOMAS D, Marsico G, Mohd Isa IL, Thirumaran A, et al
    Temporal changes guided by mesenchymal stem cells on a 3D microgel platform enhance angiogenesis in vivo at a low-cell dose.
    Proc Natl Acad Sci U S A. 2020 Jul 24. pii: 2008245117.
    PubMed     Abstract available


  68. HSU CC, Xu J, Brinkhof B, Wang H, et al
    A single-cell Raman-based platform to identify developmental stages of human pluripotent stem cell-derived neurons.
    Proc Natl Acad Sci U S A. 2020 Jul 21. pii: 2001906117.
    PubMed     Abstract available


  69. KUMAR A, Hill TM, Gordy LE, Suryadevara N, et al
    Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells.
    Proc Natl Acad Sci U S A. 2020;117:17156-17165.
    PubMed     Abstract available


  70. WANG T, Medynets M, Johnson KR, Doucet-O'Hare TT, et al
    Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway.
    Proc Natl Acad Sci U S A. 2020 Jul 15. pii: 2002427117.
    PubMed     Abstract available


  71. GHOSH S, Basu Ball W, Madaris TR, Srikantan S, et al
    An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter.
    Proc Natl Acad Sci U S A. 2020;117:16383-16390.
    PubMed     Abstract available


  72. LIM KRQ, Maruyama R, Echigoya Y, Nguyen Q, et al
    Inhibition of DUX4 expression with antisense LNA gapmers as a therapy for facioscapulohumeral muscular dystrophy.
    Proc Natl Acad Sci U S A. 2020;117:16509-16515.
    PubMed     Abstract available


  73. HIRATSUKA T, Bordeu I, Pruessner G, Watt FM, et al
    Regulation of ERK basal and pulsatile activity control proliferation and exit from the stem cell compartment in mammalian epidermis.
    Proc Natl Acad Sci U S A. 2020 Jul 10. pii: 2006965117.
    PubMed     Abstract available


  74. WANG X, Gerber A, Chen WY, Roeder RG, et al
    Functions of paralogous RNA polymerase III subunits POLR3G and POLR3GL in mouse development.
    Proc Natl Acad Sci U S A. 2020;117:15702-15711.
    PubMed     Abstract available


  75. MUSHTAQ M, Kovalevska L, Darekar S, Abramsson A, et al
    Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2.
    Proc Natl Acad Sci U S A. 2020;117:15673-15683.
    PubMed     Abstract available


  76. SHARMA M, Rajendrarao S, Shahani N, Ramirez-Jarquin UN, et al
    Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease.
    Proc Natl Acad Sci U S A. 2020;117:15989-15999.
    PubMed     Abstract available


  77. JU J, Hu N, Cairns DM, Liu H, et al
    Photo-cross-linkable, insulating silk fibroin for bioelectronics with enhanced cell affinity.
    Proc Natl Acad Sci U S A. 2020;117:15482-15489.
    PubMed     Abstract available


  78. COROMINAS-MURTRA B, Scheele CLGJ, Kishi K, Ellenbroek SIJ, et al
    Stem cell lineage survival as a noisy competition for niche access.
    Proc Natl Acad Sci U S A. 2020 Jul 1. pii: 1921205117.
    PubMed     Abstract available


    June 2020
  79. SAHARA S, Kodama T, Stevens CF
    A common rule governing differentiation kinetics of mouse cortical progenitors.
    Proc Natl Acad Sci U S A. 2020;117:15221-15229.
    PubMed     Abstract available


  80. HOBAN DB, Shrigley S, Mattsson B, Breger LS, et al
    Impact of alpha-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized alpha-synuclein rat model of PD.
    Proc Natl Acad Sci U S A. 2020;117:15209-15220.
    PubMed     Abstract available


  81. BUCHHOLZ DE, Carroll TS, Kocabas A, Zhu X, et al
    Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics.
    Proc Natl Acad Sci U S A. 2020;117:15085-15095.
    PubMed     Abstract available



  82. Correction for Hwang et al., GABA-stimulated adipose-derived stem cells suppress subcutaneous adipose inflammation in obesity.
    Proc Natl Acad Sci U S A. 2020 Jun 29. pii: 2011305117.
    PubMed    


  83. CANHER B, Heyman J, Savina M, Devendran A, et al
    Rocks in the auxin stream: Wound-induced auxin accumulation and ERF115 expression synergistically drive stem cell regeneration.
    Proc Natl Acad Sci U S A. 2020 Jun 29. pii: 2006620117.
    PubMed     Abstract available


  84. HUANG AY, Li P, Rodin RE, Kim SN, et al
    Parallel RNA and DNA analysis after deep sequencing (PRDD-seq) reveals cell type-specific lineage patterns in human brain.
    Proc Natl Acad Sci U S A. 2020;117:13886-13895.
    PubMed     Abstract available


  85. HEALTON SE, Pinto HD, Mishra LN, Hamilton GA, et al
    H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction.
    Proc Natl Acad Sci U S A. 2020;117:14251-14258.
    PubMed     Abstract available


  86. BHATTACHARYA B, Home P, Ganguly A, Ray S, et al
    Atypical protein kinase C iota (PKClambda/iota) ensures mammalian development by establishing the maternal-fetal exchange interface.
    Proc Natl Acad Sci U S A. 2020;117:14280-14291.
    PubMed     Abstract available


  87. LEE J, Shin JE, Lee B, Kim H, et al
    The stem cell marker Prom1 promotes axon regeneration by down-regulating cholesterol synthesis via Smad signaling.
    Proc Natl Acad Sci U S A. 2020 Jun 17. pii: 1920829117.
    PubMed     Abstract available


  88. GNEDEVA K, Wang X, McGovern MM, Barton M, et al
    Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal.
    Proc Natl Acad Sci U S A. 2020;117:13552-13561.
    PubMed     Abstract available


  89. MEINHARDT G, Haider S, Kunihs V, Saleh L, et al
    Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta.
    Proc Natl Acad Sci U S A. 2020;117:13562-13570.
    PubMed     Abstract available


  90. CLARK NM, Fisher AP, Berckmans B, Van den Broeck L, et al
    Protein complex stoichiometry and expression dynamics of transcription factors modulate stem cell division.
    Proc Natl Acad Sci U S A. 2020 Jun 15. pii: 2002166117.
    PubMed     Abstract available


  91. GERNER-MAURO KN, Akiyama H, Chen J
    Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.
    Proc Natl Acad Sci U S A. 2020;117:12182-12191.
    PubMed     Abstract available


    May 2020
  92. CARROW JK, Singh KA, Jaiswal MK, Ramirez A, et al
    Photothermal modulation of human stem cells using light-responsive 2D nanomaterials.
    Proc Natl Acad Sci U S A. 2020 May 27. pii: 1914345117.
    PubMed     Abstract available


  93. BELLING JN, Heidenreich LK, Tian Z, Mendoza AM, et al
    Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells.
    Proc Natl Acad Sci U S A. 2020;117:10976-10982.
    PubMed     Abstract available


  94. LI Y, Shan Y, Desai RV, Cox KH, et al
    Noise-driven cellular heterogeneity in circadian periodicity.
    Proc Natl Acad Sci U S A. 2020;117:10350-10356.
    PubMed     Abstract available


  95. KIM K, Lane EA, Saftien A, Wang H, et al
    Drosophila as a model for studying cystic fibrosis pathophysiology of the gastrointestinal system.
    Proc Natl Acad Sci U S A. 2020;117:10357-10367.
    PubMed     Abstract available


  96. PETIT CS, Lee JJ, Boland S, Swarup S, et al
    Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration.
    Proc Natl Acad Sci U S A. 2020;117:10565-10574.
    PubMed     Abstract available


  97. TRENTESAUX C, Fraudeau M, Pitasi CL, Lemarchand J, et al
    Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity.
    Proc Natl Acad Sci U S A. 2020 May 5. pii: 1917174117.
    PubMed     Abstract available


    April 2020
  98. QADIR MMF, Alvarez-Cubela S, Klein D, van Dijk J, et al
    Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020 Apr 30. pii: 1918314117.
    PubMed     Abstract available


  99. MCNEELY KC, Dwyer ND
    Cytokinesis and postabscission midbody remnants are regulated during mammalian brain development.
    Proc Natl Acad Sci U S A. 2020;117:9584-9593.
    PubMed     Abstract available


  100. TENA A, Zhang Y, Kyritsis N, Devorak A, et al
    Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture.
    Proc Natl Acad Sci U S A. 2020 Apr 24. pii: 1922299117.
    PubMed     Abstract available


  101. SHAO S, Koh M, Schultz PG
    Expanding the genetic code of the human hematopoietic system.
    Proc Natl Acad Sci U S A. 2020;117:8845-8849.
    PubMed     Abstract available


  102. UYHAZI KE, Yang Y, Liu N, Qi H, et al
    Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis.
    Proc Natl Acad Sci U S A. 2020;117:7851-7862.
    PubMed     Abstract available


  103. CHAKRABORTY A, Tapryal N, Venkova T, Mitra J, et al
    Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis.
    Proc Natl Acad Sci U S A. 2020;117:8154-8165.
    PubMed     Abstract available


  104. YUSTE-LISBONA FJ, Fernandez-Lozano A, Pineda B, Bretones S, et al
    ENO regulates tomato fruit size through the floral meristem development network.
    Proc Natl Acad Sci U S A. 2020;117:8187-8195.
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    Proc Natl Acad Sci U S A. 2017 Dec 27. pii: 1713710115.
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    Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock.
    Proc Natl Acad Sci U S A. 2017 Dec 20. pii: 1718759114.
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    Interferon-beta represses cancer stem cell properties in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2017 Dec 11. pii: 1713728114.
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    Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development.
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    November 2017
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    EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling.
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  315. CHENG S, Caviness K, Buehler J, Smithey M, et al
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    October 2017
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    September 2017
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    Cell volume change through water efflux impacts cell stiffness and stem cell fate.
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    May 2017
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    Loss of the homologous recombination gene rad51 leads to Fanconi anemia-like symptoms in zebrafish.
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    April 2017
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    Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease.
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    Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus.
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    February 2017
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    December 2016
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