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COVID-19: Daily Top 10 Papers

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Articles published in Nat Med

Retrieve available abstracts of 50 articles:
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Single Articles

    May 2021
  1. BIGENWALD C, Le Berichel J, Wilk CM, Chakraborty R, et al
    BRAF(V600E)-induced senescence drives Langerhans cell histiocytosis pathophysiology.
    Nat Med. 2021;27:851-861.
    PubMed     Abstract available

    April 2021
  2. CROMER MK, Camarena J, Martin RM, Lesch BJ, et al
    Gene replacement of alpha-globin with beta-globin restores hemoglobin balance in beta-thalassemia-derived hematopoietic stem and progenitor cells.
    Nat Med. 2021;27:677-687.
    PubMed     Abstract available

    March 2021
  3. TAO Y, Vermilyea SC, Zammit M, Lu J, et al
    Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys.
    Nat Med. 2021 Mar 1. pii: 10.1038/s41591-021-01257.
    PubMed     Abstract available

    January 2021
  4. GANESH K, Massague J
    Targeting metastatic cancer.
    Nat Med. 2021;27:34-44.
    PubMed     Abstract available

    December 2020
  5. KHAN TA, Revah O, Gordon A, Yoon SJ, et al
    Neuronal defects in a human cellular model of 22q11.2 deletion syndrome.
    Nat Med. 2020;26:1888-1898.
    PubMed     Abstract available

    November 2020
  6. JIN SC, Dong W, Kundishora AJ, Panchagnula S, et al
    Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus.
    Nat Med. 2020;26:1754-1765.
    PubMed     Abstract available

    September 2020
  7. BLOOR AJC, Patel A, Griffin JE, Gilleece MH, et al
    Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study.
    Nat Med. 2020 Sep 14. pii: 10.1038/s41591-020-1050.
    PubMed     Abstract available

    August 2020
  8. MURPHY MP, Koepke LS, Lopez MT, Tong X, et al
    Articular cartilage regeneration by activated skeletal stem cells.
    Nat Med. 2020 Aug 17. pii: 10.1038/s41591-020-1013.
    PubMed     Abstract available

    June 2020
  9. RIETHER C, Pabst T, Hopner S, Bacher U, et al
    Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents.
    Nat Med. 2020 Jun 29. pii: 10.1038/s41591-020-0910.
    PubMed     Abstract available

  10. BLANCHARD JW, Bula M, Davila-Velderrain J, Akay LA, et al
    Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.
    Nat Med. 2020;26:952-963.
    PubMed     Abstract available

  11. WHIFFIN N, Armean IM, Kleinman A, Marshall JL, et al
    The effect of LRRK2 loss-of-function variants in humans.
    Nat Med. 2020;26:869-877.
    PubMed     Abstract available

    April 2020
  12. PATANI R
    Human stem cell models of disease and the prognosis of academic medicine.
    Nat Med. 2020 Apr 9. pii: 10.1038/s41591-020-0814.

  13. ZENG J, Wu Y, Ren C, Bonanno J, et al
    Therapeutic base editing of human hematopoietic stem cells.
    Nat Med. 2020;26:535-541.
    PubMed     Abstract available

    March 2020
  14. TSAI AG, Glass DR, Juntilla M, Hartmann FJ, et al
    Multiplexed single-cell morphometry for hematopathology diagnostics.
    Nat Med. 2020;26:408-417.
    PubMed     Abstract available

    February 2020
  15. KOHN DB, Booth C, Kang EM, Pai SY, et al
    Lentiviral gene therapy for X-linked chronic granulomatous disease.
    Nat Med. 2020;26:200-206.
    PubMed     Abstract available

  16. MORETTI A, Fonteyne L, Giesert F, Hoppmann P, et al
    Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy.
    Nat Med. 2020;26:207-214.
    PubMed     Abstract available

    January 2020
  17. LAPERLE AH, Sances S, Yucer N, Dardov VJ, et al
    iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates.
    Nat Med. 2020 Jan 27. pii: 10.1038/s41591-019-0739.
    PubMed     Abstract available

    November 2019
  18. MORI M, Furuhashi K, Danielsson JA, Hirata Y, et al
    Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells.
    Nat Med. 2019;25:1691-1698.
    PubMed     Abstract available

  19. FRODERMANN V, Rohde D, Courties G, Severe N, et al
    Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells.
    Nat Med. 2019;25:1761-1771.
    PubMed     Abstract available

    October 2019
  20. BAI T, Li J, Sinclair A, Imren S, et al
    Expansion of primitive human hematopoietic stem cells by culture in a zwitterionic hydrogel.
    Nat Med. 2019 Oct 7. pii: 10.1038/s41591-019-0601.
    PubMed     Abstract available

    September 2019
  21. RIO P, Navarro S, Wang W, Sanchez-Dominguez R, et al
    Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia.
    Nat Med. 2019;25:1396-1401.
    PubMed     Abstract available

    July 2019
  22. MACPHERSON A, Kimmelman J
    Ethical development of stem-cell-based interventions.
    Nat Med. 2019 Jul 3. pii: 10.1038/s41591-019-0511.
    PubMed     Abstract available

    Designing stem-cell-based dopamine cell replacement trials for Parkinson's disease.
    Nat Med. 2019 Jul 1. pii: 10.1038/s41591-019-0507.
    PubMed     Abstract available

    June 2019
  24. TAKEBE T
    Creativity for a cure.
    Nat Med. 2019;25:868.

  25. YOUSEF H, Czupalla CJ, Lee D, Chen MB, et al
    Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
    Nat Med. 2019;25:988-1000.
    PubMed     Abstract available

    May 2019
    Molecular scissors cut in on stem cells.
    Nat Med. 2019 May 13. pii: 10.1038/s41591-019-0467.

  27. PASCA AM, Park JY, Shin HW, Qi Q, et al
    Human 3D cellular model of hypoxic brain injury of prematurity.
    Nat Med. 2019;25:784-791.
    PubMed     Abstract available

  28. WANG Z, Yip LY, Lee JHJ, Wu Z, et al
    Methionine is a metabolic dependency of tumor-initiating cells.
    Nat Med. 2019;25:825-837.
    PubMed     Abstract available

    April 2019
    Author Correction: Patient-derived induced pluripotent stem cells in cancer research and precision oncology.
    Nat Med. 2019 Apr 3. pii: 10.1038/s41591-019-0435.
    PubMed     Abstract available

    March 2019
  30. WU Y, Zeng J, Roscoe BP, Liu P, et al
    Highly efficient therapeutic gene editing of human hematopoietic stem cells.
    Nat Med. 2019 Mar 25. pii: 10.1038/s41591-019-0401.
    PubMed     Abstract available

  31. MARYANOVICH M, Zahalka AH, Pierce H, Pinho S, et al
    Author Correction: Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.
    Nat Med. 2019 Mar 22. pii: 10.1038/s41591-019-0425.
    PubMed     Abstract available

  32. FILBIN M, Monje M
    Developmental origins and emerging therapeutic opportunities for childhood cancer.
    Nat Med. 2019;25:367-376.
    PubMed     Abstract available

    February 2019
  33. KOFFLER J, Zhu W, Qu X, Platoshyn O, et al
    Biomimetic 3D-printed scaffolds for spinal cord injury repair.
    Nat Med. 2019;25:263-269.
    PubMed     Abstract available

    January 2019
  34. MARKTEL S, Scaramuzza S, Cicalese MP, Giglio F, et al
    Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ss-thalassemia.
    Nat Med. 2019 Jan 21. pii: 10.1038/s41591-018-0301.
    PubMed     Abstract available

    December 2018
  35. CHEN J, Kao YR, Sun D, Todorova TI, et al
    Publisher Correction: Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level.
    Nat Med. 2018 Dec 19. pii: 10.1038/s41591-018-0333.
    PubMed     Abstract available

  36. CHEN J, Kao YR, Sun D, Todorova TI, et al
    Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level.
    Nat Med. 2018 Dec 3. pii: 10.1038/s41591-018-0267.
    PubMed     Abstract available

    November 2018
  37. POLLYEA DA, Stevens BM, Jones CL, Winters A, et al
    Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.
    Nat Med. 2018 Nov 12. pii: 10.1038/s41591-018-0233.
    PubMed     Abstract available

  38. FALCAO AM, van Bruggen D, Marques S, Meijer M, et al
    Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis.
    Nat Med. 2018 Nov 12. pii: 10.1038/s41591-018-0236.
    PubMed     Abstract available

    Human skeletal stem cells identified.
    Nat Med. 2018;24:1637.

    October 2018
  40. ZHAO L, He R, Long H, Guo B, et al
    Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells.
    Nat Med. 2018;24:1536-1544.
    PubMed     Abstract available

    June 2018
  41. IHRY RJ, Worringer KA, Salick MR, Frias E, et al
    p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells.
    Nat Med. 2018 Jun 11. pii: 10.1038/s41591-018-0050.
    PubMed     Abstract available

    May 2018
  42. MARYANOVICH M, Zahalka AH, Pierce H, Pinho S, et al
    Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.
    Nat Med. 2018 May 7. pii: 10.1038/s41591-018-0030.
    PubMed     Abstract available

    April 2018
  43. CRESPO M, Vilar E, Tsai SY, Chang K, et al
    Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.
    Nat Med. 2018;24:526.
    PubMed     Abstract available

    March 2018
  44. ZHANG B, Nguyen LXT, Li L, Zhao D, et al
    Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
    Nat Med. 2018 Mar 5. pii: nm.4499. doi: 10.1038/nm.4499.
    PubMed     Abstract available

    February 2018
  45. ROSENZWEIG ES, Brock JH, Lu P, Kumamaru H, et al
    Restorative effects of human neural stem cell grafts on the primate spinal cord.
    Nat Med. 2018 Feb 26. pii: nm.4502. doi: 10.1038/nm.4502.
    PubMed     Abstract available

    December 2017
  46. HE L, Li Y, Li Y, Pu W, et al
    Enhancing the precision of genetic lineage tracing using dual recombinases.
    Nat Med. 2017;23:1488-1498.
    PubMed     Abstract available

    October 2017
  47. JIN X, Kim LJY, Wu Q, Wallace LC, et al
    Targeting glioma stem cells through combined BMI1 and EZH2 inhibition.
    Nat Med. 2017 Oct 9. doi: 10.1038/nm.4415.
    PubMed     Abstract available

  48. BATLLE E, Clevers H
    Cancer stem cells revisited.
    Nat Med. 2017;23:1124-1134.
    PubMed     Abstract available

    September 2017
  49. KUNTZ EM, Baquero P, Michie AM, Dunn K, et al
    Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells.
    Nat Med. 2017 Sep 18. doi: 10.1038/nm.4399.
    PubMed     Abstract available

    July 2017
  50. GILES DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, et al
    Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
    Nat Med. 2017;23:829-838.
    PubMed     Abstract available

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