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Stem Cell Research

Free Subscription Articles published in J Clin Invest Retrieve available abstracts of 60 articles: HTML format

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April 2024
1. NORTH D, Chakraverty R
   The road to refractory graft-versus-host disease is paved with good intentions.
   J Clin Invest. 2024;134:e177728.
   PubMed     Abstract available
   
   
   
2. ZHANG P, Fleming P, Andoniou CE, Waltner OG, et al
   IL-6-mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation.
   J Clin Invest. 2024;134:e174184.
   PubMed     Abstract available
   
   
   March 2024
3. MA H, Lu C, Ziegler J, Liu A, et al
   Absence of Stat1 in donor CD4+ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.
   J Clin Invest. 2024;134:e180350.
   PubMed    
   
   
   
4. ORAVECZ-WILSON K, Lauder E, Taylor A, Maneix L, et al
   Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.
   J Clin Invest. 2024;134:e167369.
   PubMed     Abstract available
   
   
   January 2024
5. LUO M, Bao L, Xue Y, Zhu M, et al
   ZMYND8 protects breast cancer stem cells against oxidative stress and ferroptosis through activation of NRF2.
   J Clin Invest. 2024;134:e171166.
   PubMed     Abstract available
   
   
   
6. SUN YL, Hennessey EE, Heins H, Yang P, et al
   Human pluripotent stem cell modeling of alveolar type 2 cell dysfunction caused by ABCA3 mutations.
   J Clin Invest. 2024;134:e164274.
   PubMed     Abstract available
   
   
   
7. HAIDER N, Kahn CR
   Interactions among insulin resistance, epigenetics, and donor sex in gene expression regulation of iPSC-derived myoblasts.
   J Clin Invest. 2024;134:e172333.
   PubMed     Abstract available
   
   
   
8. SIEW JJ, Chen HM, Chiu FL, Lee CW, et al
   Galectin-3 aggravates microglial activation and tau transmission in tauopathy.
   J Clin Invest. 2024;134:e165523.
   PubMed     Abstract available
   
   
   December 2023
9. MASON EC, Menon S, Schneider BR, Gaskill CF, et al
   Activation of mTOR signaling in adult lung microvascular progenitor cells accelerates lung aging.
   J Clin Invest. 2023;133:e171430.
   PubMed     Abstract available
   
   
   November 2023
10. AVNI B, Neiman D, Shaked ED, Gal-Rosenberg O, et al
    Chronic graft versus host disease detected by tissue-specific cell-free DNA methylation biomarkers.
    J Clin Invest. 2023 Nov 16:e163541. doi: 10.1172/JCI163541.
    PubMed     Abstract available
    
    
    
11. LI M, Nishimura T, Takeuchi Y, Hongu T, et al
    FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters.
    J Clin Invest. 2023;133:e166666.
    PubMed     Abstract available
    
    
    
12. VAZQUEZ-ARMENDARIZ AI, Tata PR
    Recent advances in lung organoid development and applications in disease modeling.
    J Clin Invest. 2023;133:e170500.
    PubMed     Abstract available
    
    
    
13. LOVEWELL RR, Hong J, Kundu S, Fielder CM, et al
    LAIR-1 agonism as a therapy for acute myeloid leukemia.
    J Clin Invest. 2023;133:e169519.
    PubMed     Abstract available
    
    
    October 2023
14. KABRA M, Shahi PK, Wang Y, Sinha D, et al
    Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy.
    J Clin Invest. 2023;133:e171356.
    PubMed     Abstract available
    
    
    August 2023
15. YU C, Sheng Y, Yu F, Ni H, et al
    Foxm1 haploinsufficiency drives clonal hematopoiesis and promotes a stress-related transition to hematologic malignancy in mice.
    J Clin Invest. 2023;133:e163911.
    PubMed     Abstract available
    
    
    
16. LI Q, Wang X, Song Q, Yang S, et al
    Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity.
    J Clin Invest. 2023;133:e165723.
    PubMed     Abstract available
    
    
    
17. BRANDSTADTER JD, Outen R, Maillard I
    Having it both ways: how STAT3 deficiency blocks graft-versus-host disease while preserving graft-versus-leukemia activity.
    J Clin Invest. 2023;133:e172251.
    PubMed     Abstract available
    
    
    
18. LOGAN BR, Fu D, Howard A, Fei M, et al
    Validated graft-specific biomarkers identify patients at risk for chronic graft-versus-host disease and death.
    J Clin Invest. 2023;133:e168575.
    PubMed     Abstract available
    
    
    July 2023
19. SHAH AH, Rivas SR, Doucet-O'Hare TT, Govindarajan V, et al
    Human endogenous retrovirus K contributes to a stem cell niche in glioblastoma.
    J Clin Invest. 2023;133:e167929.
    PubMed     Abstract available
    
    
    June 2023
20. LIN Y, Gu Q, Lu S, Pan Z, et al
    Ruxolitinib improves hematopoietic regeneration by restoring mesenchymal stromal cell function in acute graft-versus-host disease.
    J Clin Invest. 2023 Jun 20:e162201. doi: 10.1172/JCI162201.
    PubMed     Abstract available
    
    
    
21. PASUPULETI SK, Ramdas B, Burns SS, Palam LR, et al
    Obesity-induced inflammation exacerbates clonal hematopoiesis.
    J Clin Invest. 2023;133:e163968.
    PubMed     Abstract available
    
    
    May 2023
22. KERKERING J, Muinjonov B, Rosiewicz KS, Diecke S, et al
    iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
    J Clin Invest. 2023 May 23:e164637. doi: 10.1172/JCI164637.
    PubMed     Abstract available
    
    
    
23. EADE KT, Ansell BRE, Giles S, Fallon R, et al
    iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function.
    J Clin Invest. 2023;133:e163771.
    PubMed     Abstract available
    
    
    February 2023
24. MEERMEIER EW, Bergsagel PL
    Revisiting checkpoint inhibitors for myeloma: maintenance after stem cell transplant.
    J Clin Invest. 2023;133:e167346.
    PubMed     Abstract available
    
    
    
25. WANG YM, Taggart CB, Huber JF, Davies SM, et al
    Daytime-restricted parenteral feeding is associated with earlier oral intake in children following stem cell transplant.
    J Clin Invest. 2023;133:e167275.
    PubMed    
    
    
    January 2023
26. LEE D, Gimple RC, Wu X, Prager BC, et al
    Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.
    J Clin Invest. 2023;133:e163592.
    PubMed     Abstract available
    
    
    December 2022
27. CHOI KM, Kim JJ, Yoo J, Kim KS, et al
    The interferon-inducible protein viperin controls cancer metabolic reprogramming to enhance cancer progression.
    J Clin Invest. 2022;132:e157302.
    PubMed     Abstract available
    
    
    
28. MINNIE SA, Waltner OG, Ensbey KS, Olver SD, et al
    TIGIT inhibition and lenalidomide synergistically promote anti-myeloma immune responses after stem cell transplantation in mice.
    J Clin Invest. 2022 Dec 13:e157907. doi: 10.1172/JCI157907.
    PubMed     Abstract available
    
    
    November 2022
29. LU C, Ma H, Song L, Wang H, et al
    IFNGR/STAT1 signaling in recipient hematopoietic antigen presenting cells suppresses graft-versus-host disease.
    J Clin Invest. 2022 Nov 29:e125986. doi: 10.1172/JCI125986.
    PubMed     Abstract available
    
    
    
30. KUROKAWA K, Wang TC, Hayakawa Y
    R-spondin 3 governs secretory differentiation in the gastric oxyntic glands.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    October 2022
31. YIN N, Jin G, Ma Y, Zhao H, et al
    SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    September 2022
32. SCHUTT S, Wu Y, Kharel A, Bastian D, et al
    The druggable transcription factor Fli-1 regulates T cell immunity and tolerance in graft-versus-host disease.
    J Clin Invest. 2022 Sep 8. pii: 143950. doi: 10.1172/JCI143950.
    PubMed     Abstract available
    
    
    August 2022
33. DULMOVITS BM, Olson TS
    Does immune destruction drive all forms of bone marrow failure?
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    July 2022
34. EVANS EJ JR, DeGregori J
    Dissecting stepwise mutational impairment of megakaryopoiesis in a model of Down syndrome-associated leukemia.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
35. JAKUBISON BL, Sarkar T, Gudmundsson KO, Singh S, et al
    ID2 and HIF-1alpha collaborate to protect quiescent hematopoietic stem cells from activation, differentiation, and exhaustion.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    June 2022
36. SELLAR RS, Sperling AS, Slabicki M, Gasser JA, et al
    Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells.
    J Clin Invest. 2022 Jun 28. pii: 153514. doi: 10.1172/JCI153514.
    PubMed     Abstract available
    
    
    
37. FERRARA J, Prado-Acosta M
    Graft-versus-host disease: establishing IL-33 as an important costimulatory molecule.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
38. LIN Q, Wu L, Chatla S, Chowdhury FA, et al
    Hematopoietic stem cell regeneration through paracrine regulation of the Wnt5a/Prox1 signaling axis.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
39. GASPARINI SJ, Tessmer K, Reh M, Wieneke S, et al
    Transplanted human cones incorporate into the retina and function in a murine cone degeneration model.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
40. CASADO JA, Valeri A, Sanchez-Dominguez R, Vela P, et al
    Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia.
    J Clin Invest. 2022 Jun 7. pii: 142842. doi: 10.1172/JCI142842.
    PubMed     Abstract available
    
    
    
41. WICKS EE, Semenza GL
    Hypoxia-inducible factors: cancer progression and clinical translation.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
42. LIANG J, Huang G, Liu X, Taghavifar F, et al
    The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    May 2022
43. KTENA YP, Koldobskiy MA, Barbato MI, Fu HH, et al
    Donor T-cell DNMT3a regulates alloreactivity in murine models of hematopoietic stem cell transplantation.
    J Clin Invest. 2022 May 24. pii: 158047. doi: 10.1172/JCI158047.
    PubMed     Abstract available
    
    
    
44. DWYER GK, Mathews LR, Villegas JA, Lucas A, et al
    IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease.
    J Clin Invest. 2022 May 3. pii: 150927. doi: 10.1172/JCI150927.
    PubMed     Abstract available
    
    
    February 2022
45. JIANG L, Hao Y, Shao C, Wu Q, et al
    ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance.
    J Clin Invest. 2022 Feb 8. pii: 143397. doi: 10.1172/JCI143397.
    PubMed     Abstract available
    
    
    
46. BUTLER PC, Gale EA
    Reversing type 1 diabetes with stem cell-derived islets: a step closer to the dream?
    J Clin Invest. 2022;132.
    PubMed    
    
    
    
47. SEEBAUER CT, Graus MS, Huang L, McCann A, et al
    Non-beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    January 2022
48. GUAN Y, Hasipek M, Jiang D, Tiwari AD, et al
    Eltrombopag inhibits TET dioxygenase to contribute to hematopoietic stem cell expansion in aplastic anemia.
    J Clin Invest. 2022 Jan 27. pii: 149856. doi: 10.1172/JCI149856.
    PubMed     Abstract available
    
    
    
49. OLIVA AD, Gupta R, Issa K, Abi Hachem R, et al
    Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans.
    J Clin Invest. 2022 Jan 6. pii: 155506. doi: 10.1172/JCI155506.
    PubMed     Abstract available
    
    
    
50. LI Z, Duan H, Jia Y, Zhao C, et al
    Long-term corneal recovery by simultaneous delivery of hPSC-derived corneal endothelial precursors and nicotinamide.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    November 2021
51. PERSAUD SP, Ritchey JK, Kim S, Lim S, et al
    Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation.
    J Clin Invest. 2021 Nov 2. pii: 145501. doi: 10.1172/JCI145501.
    PubMed     Abstract available
    
    
    
52. TOKARZ VL, Delgado-Olguin P, Klip A
    Deprogram and reprogram to solve the riddle of insulin resistance.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    
53. BRAEUER RR, Walker NM, Misumi K, Mazzoni-Putman S, et al
    Transcription factor FOXF1 identifies compartmentally distinct mesenchymal cells with a role in lung allograft fibrogenesis.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    October 2021
54. CHEN Z, Lu T, Huang L, Wang Z, et al
    Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    August 2021
55. QIAN J, LeSavage BL, Hubka KM, Ma C, et al
    Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    June 2021
56. TANG XY, Xu L, Wang J, Hong Y, et al
    DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    
57. LOONG JH, Wong TL, Tong M, Sharma R, et al
    Glucose deprivation-induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    April 2021
58. WANG L, Liu Y, Stratigopoulos G, Panigrahi S, et al
    Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    March 2021
59. MUSCARELLA AM, Aguirre S, Hao X, Waldvogel SM, et al
    Exploiting bone niches: progression of disseminated tumor cells to metastasis.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    
60. OSUKA S, Zhu D, Zhang Z, Li C, et al
    N-cadherin upregulation mediates adaptive radioresistance in glioblastoma.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    

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