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Stem Cell Research

Free Subscription Articles published in J Clin Invest Retrieve available abstracts of 53 articles: HTML format

Single Articles

May 2025
1. D'ADDIO F, Amabile G, Assi E, Maestroni A, et al
   TMEM219 signaling promotes intestinal stem cell death and exacerbates colitis.
   J Clin Invest. 2025;135:e185783.
   PubMed     Abstract available
   
   
   
2. SCHLEGEL N
   Promoting mucosal healing by targeting TMEM219-dependent intestinal epithelial stem cell defects in inflammatory bowel disease.
   J Clin Invest. 2025;135:e192640.
   PubMed     Abstract available
   
   
   
3. HUANG Y, Xie X, Liu M, Zhang Y, et al
   Restoring mitochondrial function promotes hematopoietic reconstitution from cord blood following cryopreservation-related functional decline.
   J Clin Invest. 2025;135:e183607.
   PubMed     Abstract available
   
   
   April 2025
4. GATTU AK, Tanzer M, Yaron-Barir TM, Johnson JL, et al
   Cell-intrinsic insulin signaling defects in human iPS cell-derived hepatocytes in type 2 diabetes.
   J Clin Invest. 2025;135:e183513.
   PubMed     Abstract available
   
   
   
5. GAO C, Dai Y, Spezza PA, Boasiako P, et al
   Megakaryocytes transfer mitochondria to bone marrow mesenchymal stromal cells to lower platelet activation.
   J Clin Invest. 2025;135:e189801.
   PubMed     Abstract available
   
   
   
6. KANG M, Choi J, Han J, Araki T, et al
   Aberrant ERK signaling in astrocytes impairs learning and memory in RASopathy-associated BRAF mutant mouse models.
   J Clin Invest. 2025;135:e176631.
   PubMed     Abstract available
   
   
   March 2025
7. DELAFONTAINE S, Meyts I
   Oncostatin M silence and neopeptide: the value of exploring patients with rare inherited bone marrow failure.
   J Clin Invest. 2025;135:e190955.
   PubMed     Abstract available
   
   
   February 2025
8. LI H, Liu P, Xu S, Li Y, et al
   FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
   J Clin Invest. 2025;135:e191424.
   PubMed    
   
   
   
9. WEI W, Gao X, Qian J, Li L, et al
   Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival.
   J Clin Invest. 2025;135:e177375.
   PubMed     Abstract available
   
   
   January 2025
10. HAMAMOTO K, Zhu G, Lai Q, Lesperance J, et al
    HoxBlinc lncRNA reprograms CTCF-independent TADs to drive leukemic transcription and HSC dysregulation in NUP98-rearranged leukemia.
    J Clin Invest. 2025;135:e184743.
    PubMed     Abstract available
    
    
    
11. CUI X, Hou L, Yan B, Liu J, et al
    Sex dimorphism in the mouse bone marrow niche regulates hematopoietic engraftment via sex-specific Kdm5c/Cxcl12 signaling.
    J Clin Invest. 2025 Jan 21:e182125. doi: 10.1172/JCI182125.
    PubMed     Abstract available
    
    
    
12. GRIFFITH JW, Luster AD
    No bones about it: regulatory T cells promote fracture healing.
    J Clin Invest. 2025;135:e188368.
    PubMed     Abstract available
    
    
    
13. LI J, Bai J, Pham VT, Hashimoto M, et al
    Loss of Cpt1a results in elevated glucose-fueled mitochondrial oxidative phosphorylation and defective hematopoietic stem cells.
    J Clin Invest. 2025 Jan 9:e184069. doi: 10.1172/JCI184069.
    PubMed     Abstract available
    
    
    
14. CHEN S, Huang C, Li K, Cheng M, et al
    Tumor-initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice.
    J Clin Invest. 2025;135:e180893.
    PubMed     Abstract available
    
    
    
15. CHEN YT, Jiang MM, Leynes C, Adeyeye M, et al
    ATRX silences Cartpt expression in osteoblastic cells during skeletal development.
    J Clin Invest. 2025;135:e163587.
    PubMed     Abstract available
    
    
    
16. CAMPBELL K, Li Q
    Clonal hematopoiesis JAKs up plaque formation.
    J Clin Invest. 2025;135:e187529.
    PubMed     Abstract available
    
    
    
17. WANG BZ, Morsink MA, Kim SW, Luo LJ, et al
    Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy.
    J Clin Invest. 2025;135:e181630.
    PubMed     Abstract available
    
    
    December 2024
18. SAARELA D, Lis P, Gomes S, Nirujogi RS, et al
    Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples.
    J Clin Invest. 2024;135:e183592.
    PubMed     Abstract available
    
    
    
19. DEFAMIE V, Aliar K, Sarkar S, Vyas F, et al
    Metalloproteinase inhibitors regulate biliary progenitor cells through sDLK1 in organoid models of liver injury.
    J Clin Invest. 2024;135:e164997.
    PubMed     Abstract available
    
    
    
20. KIM Y, Kim SW, Saul D, Neyazi M, et al
    Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.
    J Clin Invest. 2024;135:e183353.
    PubMed     Abstract available
    
    
    
21. WU Q, Yu C, Yu F, Guo Y, et al
    Evi1 governs Kdm6b-mediated histone demethylation to regulate the Laptm4b-driven mTOR pathway in hematopoietic progenitor cells.
    J Clin Invest. 2024;134:e173403.
    PubMed     Abstract available
    
    
    
22. PEACH T, Quattrocelli M
    The muscle stem cell case of Benjamin Button: rejuvenating muscle regenerative capacity through nutraceuticals.
    J Clin Invest. 2024;134:e185054.
    PubMed     Abstract available
    
    
    
23. WANG Q, Hu T, Zhang Q, Zhang Y, et al
    Fusobacterium nucleatum promotes colorectal cancer through neogenesis of tumor stem cells.
    J Clin Invest. 2024 Dec 10:e181595. doi: 10.1172/JCI181595.
    PubMed     Abstract available
    
    
    November 2024
24. NAYAK RC, Emberesh S, Trump LR, Wellendorf AM, et al
    G-CSF resistance of ELANE-mutant neutropenia depends on SERF1-containing truncated-neutrophil elastase aggregates.
    J Clin Invest. 2024;135:e177342.
    PubMed     Abstract available
    
    
    
25. WANG S, Huang T, Wu Q, Yuan H, et al
    Lactate reprograms glioblastoma immunity through CBX3-regulated histone lactylation.
    J Clin Invest. 2024;134:e176851.
    PubMed     Abstract available
    
    
    
26. ANCEL S, Michaud J, Migliavacca E, Jomard C, et al
    Nicotinamide and pyridoxine stimulate muscle stem cell expansion and enhance regenerative capacity during aging.
    J Clin Invest. 2024 Nov 12:e163648. doi: 10.1172/JCI163648.
    PubMed     Abstract available
    
    
    
27. PALLAVICINI G, Moccia A, Iegiani G, Parolisi R, et al
    Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity.
    J Clin Invest. 2024;134:e175435.
    PubMed     Abstract available
    
    
    October 2024
28. LIU Q, Huang J, Ding H, Tao Y, et al
    Flavin-containing monooxygenase 2 confers cardioprotection in ischemia models through its disulfide bond catalytic activity.
    J Clin Invest. 2024;134:e177077.
    PubMed     Abstract available
    
    
    
29. SINHA S, Callow BW, Farfel AP, Roy S, et al
    Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels.
    J Clin Invest. 2024;134:e170953.
    PubMed     Abstract available
    
    
    
30. GHOTBI E, Tchegnon E, Chen Z, Li S, et al
    Transcription factor KROX20 marks epithelial stem cells for hair follicle formation.
    J Clin Invest. 2024 Oct 3:e180160. doi: 10.1172/JCI180160.
    PubMed     Abstract available
    
    
    
31. CHEN CL, Tsukamoto H, Liu JC, Kashiwabara C, et al
    Reciprocal regulation by TLR4 and TGF-beta in tumor-initiating stem-like cells.
    J Clin Invest. 2024;134:e186923.
    PubMed    
    
    
    September 2024
32. YANG H, Ping X, Zhou J, Ailifeire H, et al
    Reversible cold-induced lens opacity in a hibernator reveals a molecular target for treating cataracts.
    J Clin Invest. 2024;134:e169666.
    PubMed     Abstract available
    
    
    
33. LIU H, Zhao XF, Lu YN, Hayes LR, et al
    CRISPR/Cas13d targeting suppresses repeat-associated non-AUG translation of C9orf72 hexanucleotide repeat RNA.
    J Clin Invest. 2024;134:e179016.
    PubMed     Abstract available
    
    
    
34. DESCHAMPS P, Wacheux M, Gosseye A, Morabito M, et al
    CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia.
    J Clin Invest. 2024;134:e180738.
    PubMed     Abstract available
    
    
    
35. XING W, Feng H, Jiang B, Gao B, et al
    Itm2a expression marks periosteal skeletal stem cells that contribute to bone fracture healing.
    J Clin Invest. 2024;134:e176528.
    PubMed     Abstract available
    
    
    August 2024
36. BORDENAVE J, Gajda D, Michonneau D, Vallet N, et al
    Deciphering bone marrow engraftment after allogeneic stem cell transplantation in humans using single cell analyses.
    J Clin Invest. 2024 Aug 29:e180331. doi: 10.1172/JCI180331.
    PubMed     Abstract available
    
    
    
37. WALKER NM, Ibuki Y, McLinden AP, Misumi K, et al
    MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction.
    J Clin Invest. 2024;134:e168393.
    PubMed     Abstract available
    
    
    
38. SRIDHAR A, DeSantiago J, Chen H, Pavel MA, et al
    Modulation of NOX2 causes obesity-mediated atrial fibrillation.
    J Clin Invest. 2024;134:e175447.
    PubMed     Abstract available
    
    
    
39. SCHLEICHER WE, Hoag B, De Dominici M, DeGregori J, et al
    CHIP: a clonal odyssey of the bone marrow niche.
    J Clin Invest. 2024;134:e180068.
    PubMed     Abstract available
    
    
    July 2024
40. WU K, Zhang Y, Yin-DeClue H, Sun K, et al
    A correctable immune niche for epithelial stem-cell reprogramming and post-viral lung diseases.
    J Clin Invest. 2024 Jul 25:e183092. doi: 10.1172/JCI183092.
    PubMed     Abstract available
    
    
    June 2024
41. MAROM R, Song IW, Busse EC, Washington ME, et al
    The IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect.
    J Clin Invest. 2024;134:e170369.
    PubMed     Abstract available
    
    
    May 2024
42. SELGRADE DF, Fullenkamp DE, Chychula IA, Li B, et al
    Susceptibility to innate immune activation in genetically mediated myocarditis.
    J Clin Invest. 2024;134:e180254.
    PubMed     Abstract available
    
    
    
43. SAUL D, Doolittle ML, Rowsey JL, Froemming MN, et al
    Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair.
    J Clin Invest. 2024;134:e179834.
    PubMed     Abstract available
    
    
    
44. LEOW DM, Ng YK, Wang LC, Koh HW, et al
    Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy.
    J Clin Invest. 2024;134:e173702.
    PubMed     Abstract available
    
    
    
45. LENARDIC A, Domenig SA, Zvick J, Bundschuh N, et al
    Generation of allogenic and xenogeneic functional muscle stem cells for intramuscular transplantation.
    J Clin Invest. 2024 May 7:e166998. doi: 10.1172/JCI166998.
    PubMed     Abstract available
    
    
    April 2024
46. MOE A, Rayasam A, Sauber G, Shah RK, et al
    Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft versus host disease.
    J Clin Invest. 2024 Apr 25:e175205. doi: 10.1172/JCI175205.
    PubMed     Abstract available
    
    
    
47. SONG X, Tiek D, Miki S, Huang T, et al
    RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma.
    J Clin Invest. 2024;134:e173789.
    PubMed     Abstract available
    
    
    
48. KEAN LS, Blazar BR
    Major breakthroughs in hematopoietic stem cell transplantation and future challenges in clinical implementation.
    J Clin Invest. 2024;134:e179944.
    PubMed    
    
    
    
49. NORTH D, Chakraverty R
    The road to refractory graft-versus-host disease is paved with good intentions.
    J Clin Invest. 2024;134:e177728.
    PubMed     Abstract available
    
    
    
50. ZHANG P, Fleming P, Andoniou CE, Waltner OG, et al
    IL-6-mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation.
    J Clin Invest. 2024;134:e174184.
    PubMed     Abstract available
    
    
    March 2024
51. MA H, Lu C, Ziegler J, Liu A, et al
    Absence of Stat1 in donor CD4+ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.
    J Clin Invest. 2024;134:e180350.
    PubMed    
    
    
    
52. ORAVECZ-WILSON K, Lauder E, Taylor A, Maneix L, et al
    Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.
    J Clin Invest. 2024;134:e167369.
    PubMed     Abstract available
    
    
    January 2024
53. LUO M, Bao L, Xue Y, Zhu M, et al
    ZMYND8 protects breast cancer stem cells against oxidative stress and ferroptosis through activation of NRF2.
    J Clin Invest. 2024;134:e171166.
    PubMed     Abstract available
    
    

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