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Articles published in Cancer Res

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    June 2021
  1. CIERI N, Maurer K, Wu CJ
    60 Years Young: The Evolving Role of Allogeneic Hematopoietic Stem Cell Transplantation in Cancer Immunotherapy.
    Cancer Res. 2021 Jun 9. pii: 0008-5472.CAN-21-0301.
    PubMed     Abstract available

    May 2021
  2. BOMMI PV, Bowen CM, Reyes-Uribe L, Wu W, et al
    The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells.
    Cancer Res. 2021;81:2760-2773.
    PubMed     Abstract available

  3. DENG X, Tchieu J, Higginson DS, Hsu KS, et al
    Disabling the Fanconi Anemia Pathway in Stem Cells Leads to Radioresistance and Genomic Instability.
    Cancer Res. 2021 May 3. pii: 0008-5472.CAN-20-3309.
    PubMed     Abstract available

    April 2021
  4. LEUNG HW, Leung CO, Lau EY, Chung KPS, et al
    EPHB2 activates beta-catenin to enhance cancer stem cell properties and drive sorafenib resistance in hepatocellular carcinoma.
    Cancer Res. 2021 Apr 26. pii: 0008-5472.CAN-21-0184.
    PubMed     Abstract available

  5. ALVAREZ-TROTTA A, Guerrant W, Astudillo L, Lahiry M, et al
    Pharmacological disruption of the Notch1 transcriptional complex inhibits tumor growth by selectively targeting cancer stem cells.
    Cancer Res. 2021 Apr 5. pii: 0008-5472.CAN-20-3611.
    PubMed     Abstract available

    March 2021
  6. SILVERMAN DA, Martinez VK, Dougherty PM, Myers JN, et al
    Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk.
    Cancer Res. 2021;81:1431-1440.
    PubMed     Abstract available

    February 2021
  7. PARDINI B, Dragomir MP
    SCIRT lncRNA Blocks the Shot of Breast Cancer Cells Self-Renewal Mechanism.
    Cancer Res. 2021;81:535-536.
    PubMed     Abstract available

    January 2021
  8. SANDIFORD OA, Donnelly RJ, El-Far M, Burgmeyer LM, et al
    Mesenchymal stem cell-secreted extracellular vesicles instruct stepwise dedifferentiation of breast cancer cells into dormancy at the bone marrow perivascular region.
    Cancer Res. 2021 Jan 26. pii: 0008-5472.CAN-20-2434.
    PubMed     Abstract available

  9. NEY GM, Yang KB, Ng V, Liu L, et al
    Oncogenic N-Ras mitigates oxidative stress-induced apoptosis of hematopoietic stem cells.
    Cancer Res. 2021 Jan 13. pii: 0008-5472.CAN-20-0118.
    PubMed     Abstract available

  10. GANGULY K, Krishn SR, Rachagani S, Jahan R, et al
    Secretory Mucin 5AC Promotes Neoplastic Progression by Augmenting KLF4-Mediated Pancreatic Cancer Cell Stemness.
    Cancer Res. 2021;81:91-102.
    PubMed     Abstract available

  11. STEENBRUGGE J, De Jaeghere EA, Meyer E, Denys H, et al
    Splenic Hematopoietic and Stromal Cells in Cancer Progression.
    Cancer Res. 2021;81:27-34.
    PubMed     Abstract available

    December 2020
  12. HAGIWARA M, Yasumizu Y, Yamashita N, Rajabi H, et al
    Cancer Res. 2020 Dec 15. pii: 0008-5472.CAN-20-2588.
    PubMed     Abstract available

  13. TORTI SV, Torti FM
    Iron and Cancer: 2020 Vision.
    Cancer Res. 2020;80:5435-5448.
    PubMed     Abstract available

  14. ORAVECZ-WILSON K, Rossi C, Zajac C, Sun Y, et al
    ATG5-dependent autophagy uncouples T cell proliferative and effector functions and separates graft-versus-host disease from graft-versus-leukemia.
    Cancer Res. 2020 Dec 4. pii: 0008-5472.CAN-20-1346.
    PubMed     Abstract available

    November 2020
  15. WANG Y, Zhao G, Condello S, Huang H, et al
    Frizzled-7 Identifies Platinum Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis.
    Cancer Res. 2020 Nov 10. pii: 0008-5472.CAN-20-1488.
    PubMed     Abstract available

  16. TAGAL V, Roth MG
    Loss of Aurora kinase signaling allows lung cancer cells to adopt endoreplication and form polyploid giant cancer cells that resist antimitotic drugs.
    Cancer Res. 2020 Nov 10. pii: 0008-5472.CAN-20-1693.
    PubMed     Abstract available

  17. LI J, Liao T, Liu H, Yuan H, et al
    Hypoxic glioma stem cell-derived exosomes containing Linc01060 promote progression of glioma by regulating the MZF1/c-Myc/HIF-1alpha.
    Cancer Res. 2020 Nov 6. pii: 0008-5472.CAN-20-2270.
    PubMed     Abstract available

    October 2020
  18. RESTALL IJ, Cseh O, Richards LM, Pugh TJ, et al
    Brain tumor stem cell dependence on glutaminase reveals a metabolic vulnerability through the amino acid deprivation response pathway.
    Cancer Res. 2020 Oct 26. pii: 0008-5472.CAN-19-3923.
    PubMed     Abstract available

  19. CHAMBERLIN T, Clack M, Silvers C, Kuziel G, et al
    Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation.
    Cancer Res. 2020;80:4465-4475.
    PubMed     Abstract available

  20. WANG TW, Chern E, Hsu CW, Tseng KC, et al
    SIRT1-mediated expression of CD24 and epigenetic suppression of novel tumor suppressor miR-1185-1 increases colorectal cancer stemness.
    Cancer Res. 2020 Oct 12. pii: 0008-5472.CAN-19-3188.
    PubMed     Abstract available

  21. LEAVITT RJ, Acharya MM, Baulch JE, Limoli CL, et al
    Extracellular Vesicle-Derived miR-124 Resolves Radiation-Induced Brain Injury.
    Cancer Res. 2020;80:4266-4277.
    PubMed     Abstract available

    September 2020
  22. STIEHL T, Wang W, Lutz C, Marciniak-Czochra A, et al
    Mathematical Modeling Provides Evidence for Niche Competition in Human AML and Serves as a Tool to Improve Risk Stratification.
    Cancer Res. 2020;80:3983-3992.
    PubMed     Abstract available

  23. BHAT-NAKSHATRI P, Kumar B, Simpson E, Ludwig KK, et al
    Breast cancer cell detection and characterization from breast milk-derived cells.
    Cancer Res. 2020 Sep 15. pii: 0008-5472.CAN-20-1030.
    PubMed     Abstract available

  24. VOSS DM, Sloan A, Spina R, Ames HM, et al
    The Alternative Splicing Factor MBNL1 Inhibits Glioblastoma Tumor Initiation and Progression by Reducing Hypoxia-Induced Stemness.
    Cancer Res. 2020 Sep 14. pii: 0008-5472.CAN-20-1233.
    PubMed     Abstract available

  25. ALAM IS, Simonetta F, Scheller L, Mayer AT, et al
    Visualization of activated T cells by OX40-immunoPET as a strategy for diagnosis of acute Graft-versus-Host-Disease.
    Cancer Res. 2020 Sep 8. pii: 0008-5472.CAN-20-1149.
    PubMed     Abstract available

  26. NGUYEN CH, Schlerka A, Grandits AM, Koller E, et al
    IL2RA promotes aggressiveness and stem cell-related properties of acute myeloid leukemia.
    Cancer Res. 2020 Sep 1. pii: 0008-5472.CAN-20-0531.
    PubMed     Abstract available

    August 2020
  27. SHIOKAWA D, Sakai H, Ohata H, Miyazaki T, et al
    Slow-cycling cancer stem cells regulate progression and chemoresistance in colon cancer.
    Cancer Res. 2020 Aug 19. pii: 0008-5472.CAN-20-0378.
    PubMed     Abstract available

  28. ZONG X, Wang W, Ozes A, Fang F, et al
    EZH2-mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells.
    Cancer Res. 2020 Aug 19. pii: 0008-5472.CAN-20-0458.
    PubMed     Abstract available

  29. KONCAR RF, Agnihotri S
    Anarchy or Respect the Hierarchy? The Complexity of Glioblastoma.
    Cancer Res. 2020;80:3195-3196.
    PubMed     Abstract available

  30. ALMAIRAC F, Turchi L, Sakakini N, Debruyne DN, et al
    ERK-Mediated Loss of miR-199a-3p and Induction of EGR1 Act as a "Toggle Switch" of GBM Cell Dedifferentiation into NANOG- and OCT4-Positive Cells.
    Cancer Res. 2020;80:3236-3250.
    PubMed     Abstract available

  31. LI Y, Zhang X, Zhu S, Dejene EA, et al
    HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma.
    Cancer Res. 2020;80:3265-3278.
    PubMed     Abstract available

  32. GOMEZ KE, Wu F, Keysar SB, Morton JJ, et al
    Cancer cell CD44 mediates macrophage/monocyte-driven regulation of head and neck cancer stem cells.
    Cancer Res. 2020 Aug 14. pii: 0008-5472.CAN-20-1079.
    PubMed     Abstract available

  33. AMBROSONE CB, Higgins MJ
    Relationships between breast feeding and breast cancer subtypes: lessons learned from studies in humans and in mice.
    Cancer Res. 2020 Aug 14. pii: 0008-5472.CAN-20-0077.
    PubMed     Abstract available

    July 2020
  34. DATTILO R, Mottini C, Camera E, Lamolinara A, et al
    Pyrvinium pamoate induces death of triple-negative breast cancer stem-like cells and reduces metastases through effects on lipid anabolism.
    Cancer Res. 2020 Jul 23. pii: 0008-5472.CAN-19-1184.
    PubMed     Abstract available

  35. BRIDGES AE, Ramachandran S, Pathania R, Parwal U, et al
    RAD51AP1 deficiency reduces tumor growth by targeting stem cell self-renewal.
    Cancer Res. 2020 Jul 14. pii: 0008-5472.CAN-19-3713.
    PubMed     Abstract available

    June 2020
  36. HUANG H, Wang Y, Kandpal M, Zhao G, et al
    FTO-Dependent N6-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling.
    Cancer Res. 2020 Jun 30. pii: 0008-5472.CAN-19-4044.
    PubMed     Abstract available

  37. YOKOMIZO-NAKANO T, Kubota S, Bai J, Hamashima A, et al
    Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome.
    Cancer Res. 2020;80:2523-2536.
    PubMed     Abstract available

  38. CHEN Y, Wang T, Huang M, Liu Q, et al
    MAFB Promotes Cancer Stemness and Tumorigenesis in Osteosarcoma through a Sox9-Mediated Positive Feedback Loop.
    Cancer Res. 2020;80:2472-2483.
    PubMed     Abstract available

    May 2020
  39. TROTTER TN, Shuptrine CW, Tsao LC, Marek RD, et al
    IL-26, a non-canonical mediator of DNA inflammatory stimulation, promotes TNBC engraftment and progression in association with neutrophils.
    Cancer Res. 2020 May 4. pii: 0008-5472.CAN-18-3825.
    PubMed     Abstract available

  40. CHEN J, Mitra A, Li S, Song S, et al
    Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFbeta Signaling.
    Cancer Res. 2020;80:1819-1832.
    PubMed     Abstract available

    April 2020
  41. LOPEZ-BERTONI H, Kotchetkov IS, Mihelson N, Lal B, et al
    A Sox2:miR-486-5p Axis Regulates Survival of GBM Cells by Inhibiting Tumor Suppressor Networks.
    Cancer Res. 2020;80:1644-1655.
    PubMed     Abstract available

  42. LIU X, Hu M, Liu P, Jiao M, et al
    ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming.
    Cancer Res. 2020;80:1669-1680.
    PubMed     Abstract available

  43. MOSHKOVICH N, Ochoa HJ, Tang B, Yang HH, et al
    Peptidylarginine deiminase IV (PADI4) regulates breast cancer stem cells via a novel tumor cell-autonomous suppressor role.
    Cancer Res. 2020 Apr 7. pii: 0008-5472.CAN-19-3018.
    PubMed     Abstract available

  44. MEULEMANS L, Mesman RLS, Caputo SM, Krieger S, et al
    Skipping Nonsense to Maintain Function: The Paradigm of BRCA2 Exon 12.
    Cancer Res. 2020;80:1374-1386.
    PubMed     Abstract available

  45. CHANDRA A, Jahangiri A, Chen W, Nguyen AT, et al
    Clonal ZEB1-Driven Mesenchymal Transition Promotes Targetable Oncologic Antiangiogenic Therapy Resistance.
    Cancer Res. 2020;80:1498-1511.
    PubMed     Abstract available

  46. ANDERSSON N, Bakker B, Karlsson J, Valind A, et al
    Extensive Clonal Branching Shapes the Evolutionary History of High-Risk Pediatric Cancers.
    Cancer Res. 2020;80:1512-1523.
    PubMed     Abstract available

    March 2020
  47. BRUSCHI M, Garnier L, Cleroux E, Giordano A, et al
    Loss of APC Rapidly Impairs DNA Methylation Programs and Cell Fate Decisions in LGR5+ Intestinal Stem Cells.
    Cancer Res. 2020 Mar 25. pii: 0008-5472.CAN-19-2104.
    PubMed     Abstract available

  48. ZHAO Y, Kaushik N, Kang JH, Kaushik NK, et al
    A Feedback loop comprising EGF/TGF-alpha Sustains TFCP2-mediated Breast Cancer Progression.
    Cancer Res. 2020 Mar 19. pii: 0008-5472.CAN-19-2908.
    PubMed     Abstract available

  49. MUSCHEL RJ, Hammond EM, Dewhirst MW
    A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities.
    Cancer Res. 2020;80:927-928.
    PubMed     Abstract available

  50. SAMI E, Paul BT, Koziol JA, ElShamy WM, et al
    The Immunosuppressive Microenvironment in BRCA1-IRIS-Overexpressing TNBC Tumors Is Induced by Bidirectional Interaction with Tumor-Associated Macrophages.
    Cancer Res. 2020;80:1102-1117.
    PubMed     Abstract available

    February 2020
  51. CHA HR, Lee JH, Ponnazhagan S
    Revisiting Immunotherapy: A Focus on Prostate Cancer.
    Cancer Res. 2020 Feb 17. pii: 0008-5472.CAN-19-2948.
    PubMed     Abstract available

  52. THORKELSSON A, Merlino G, Michael H
    Build-a-Mouse: Melanoma Modeling Picks up Speed.
    Cancer Res. 2020;80:655-656.
    PubMed     Abstract available

  53. RUAN S, Lin M, Zhu Y, Lum L, et al
    Integrin beta4-Targeted Cancer Immunotherapies Inhibit Tumor Growth and Decrease Metastasis.
    Cancer Res. 2020;80:771-783.
    PubMed     Abstract available

  54. NAZARI F, Oklejas AE, Nor JE, Pearson AT, et al
    In silico models accurately predict in vivo response for IL-6 blockade in head and neck cancer.
    Cancer Res. 2020 Feb 10. pii: 0008-5472.CAN-19-1846.
    PubMed     Abstract available

  55. HEBERT JD, Myers SA, Naba A, Abbruzzese G, et al
    Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches.
    Cancer Res. 2020 Feb 4. pii: 0008-5472.CAN-19-2961.
    PubMed     Abstract available

  56. GRAMANTIERI L, Pollutri D, Gagliardi M, Giovannini C, et al
    MiR-30e-3p influences tumor phenotype through MDM2/TP53 axis and predicts sorafenib resistance in hepatocellular carcinoma.
    Cancer Res. 2020 Feb 3. pii: 0008-5472.CAN-19-0472.
    PubMed     Abstract available

    January 2020
  57. NAVAS T, Kinders RJ, Lawrence SM, Ferry-Galow KV, et al
    Clinical Evolution of Epithelial-Mesenchymal Transition in Human Carcinomas.
    Cancer Res. 2020;80:304-318.
    PubMed     Abstract available

  58. KEYSAR SB, Gomes N, Miller B, Jackson BC, et al
    Inhibiting translation elongation with SVC112 suppresses cancer stem cells and inhibits growth in head and neck squamous carcinoma.
    Cancer Res. 2020 Jan 7. pii: 0008-5472.CAN-19-3232.
    PubMed     Abstract available

    December 2019
  59. NACARELLI T, Fukumoto T, Zundell JA, Fatkhutdinov N, et al
    NAMPT inhibition suppresses cancer stem-like cells associated with therapy-induced senescence in ovarian cancer.
    Cancer Res. 2019 Dec 19. pii: 0008-5472.CAN-19-2830.
    PubMed     Abstract available

    November 2019
  60. SACHS K, Sarver AL, Noble-Orcutt KE, LaRue RS, et al
    Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia.
    Cancer Res. 2019 Nov 29. pii: 0008-5472.CAN-18-2932.
    PubMed     Abstract available

  61. KONDO T, Ando M, Nagai N, Tomisato W, et al
    The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells.
    Cancer Res. 2019 Nov 25. pii: 0008-5472.CAN-19-1196.
    PubMed     Abstract available

  62. BOK I, Vera O, Xu X, Jasani N, et al
    A versatile ES cell-based melanoma mouse modeling platform.
    Cancer Res. 2019 Nov 19. pii: 0008-5472.CAN-19-2924.
    PubMed     Abstract available

  63. LI C, Course MM, McNeish IA, Drescher CW, et al
    Prophylactic in vivo hematopoietic stem cell gene therapy with an immune checkpoint inhibitor reverses tumor growth in syngeneic mouse tumor models.
    Cancer Res. 2019 Nov 14. pii: 0008-5472.CAN-19-1044.
    PubMed     Abstract available

  64. MARTIN ML, Adileh M, Hsu KS, Hua G, et al
    Organoids reveal that inherent radiosensitivity of small and large intestinal stem cells determines organ sensitivity.
    Cancer Res. 2019 Nov 5. pii: 0008-5472.CAN-19-0312.
    PubMed     Abstract available

    October 2019
  65. MCABEE JH, Rath BH, Valdez K, Young DL, et al
    Radiation drives the evolution of orthotopic xenografts initiated from glioblastoma stem-like cells.
    Cancer Res. 2019 Oct 15. pii: 0008-5472.CAN-19-2452.
    PubMed     Abstract available

  66. TRAVNICKOVA J, Wojciechowska S, Khamseh A, Gautier P, et al
    Zebrafish MITF-low melanoma subtype models reveal transcriptional subclusters and MITF-independent residual disease.
    Cancer Res. 2019 Oct 3. pii: 0008-5472.CAN-19-0037.
    PubMed     Abstract available

  67. LIBBY CJ, McConathy J, Darley-Usmar V, Hjelmeland AB, et al
    The Role of Metabolic Plasticity in Blood and Brain Stem Cell Pathophysiology.
    Cancer Res. 2019 Oct 1. pii: 0008-5472.CAN-19-1169.
    PubMed     Abstract available

    September 2019
  68. LI F, Yi Y, Miao Y, Long W, et al
    N6-methyladenosine Modulates Nonsense-mediated mRNA Decay in Human Glioblastoma.
    Cancer Res. 2019 Sep 17. pii: 0008-5472.CAN-18-2868.
    PubMed     Abstract available

  69. LY M, Rentas S, Vujovic A, Wong N, et al
    Diminished AHR signaling drives human acute myeloid leukemia stem cell maintenance.
    Cancer Res. 2019 Sep 13. pii: 0008-5472.CAN-19-0274.
    PubMed     Abstract available

  70. JUNG J, Zhang Y, Celiku O, Zhang W, et al
    Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma.
    Cancer Res. 2019 Sep 5. pii: 0008-5472.CAN-19-0198.
    PubMed     Abstract available

    August 2019
  71. MUKOHYAMA J, Isobe T, Hu Q, Hayashi T, et al
    miR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells.
    Cancer Res. 2019 Aug 15. pii: 0008-5472.CAN-18-3544.
    PubMed     Abstract available

  72. PEIFFER DS, Wyatt D, Zlobin A, Piracha A, et al
    DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor-positive Breast Cancer following endocrine therapy.
    Cancer Res. 2019 Aug 6. pii: 0008-5472.CAN-19-1110.
    PubMed     Abstract available

    July 2019
  73. BURSLEM GM, Schultz AR, Bondeson DP, Eide CA, et al
    Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-mediated Targeted Protein Degradation.
    Cancer Res. 2019 Jul 16. pii: 0008-5472.CAN-19-1236.
    PubMed     Abstract available

  74. YE S, Ding YF, Jia WH, Liu XL, et al
    SET domain-containing protein 4 epigenetically controls breast cancer stem cell quiescence.
    Cancer Res. 2019 Jul 15. pii: 0008-5472.CAN-19-1084.
    PubMed     Abstract available

  75. YOON AR, Hong J, Li Y, Shin HC, et al
    Mesenchymal stem cell-mediated delivery of an oncolytic adenovirus enhances antitumor efficacy in hepatocellular carcinoma.
    Cancer Res. 2019 Jul 9. pii: 0008-5472.CAN-18-3900.
    PubMed     Abstract available

  76. PRIETO-VILA M, Usuba W, Takahashi RU, Shimomura I, et al
    Single-cell Analysis Reveals a Preexisting Drug-Resistant Subpopulation in the Luminal Breast Cancer Subtype.
    Cancer Res. 2019 Jul 9. pii: 0008-5472.CAN-19-0122.
    PubMed     Abstract available

  77. DAS B, Pal B, Bhuyan R, Li H, et al
    MYC regulates the HIF-2alpha stemness pathway via Nanog and Sox2 to maintain self-renewal in cancer stem cells versus non-stem cancer cells.
    Cancer Res. 2019 Jul 2. pii: 0008-5472.CAN-18-2847.
    PubMed     Abstract available

    June 2019
  78. WANG D, Fu L, Wei J, Xiong Y, et al
    PPARdelta mediates the effect of dietary fat in promoting colorectal cancer metastasis.
    Cancer Res. 2019 Jun 25. pii: 0008-5472.CAN-19-0384.
    PubMed     Abstract available

  79. TAKAHASHI N, Nobusue H, Shimizu T, Sugihara E, et al
    ROCK Inhibition Induces Terminal Adipocyte Differentiation and Suppresses Tumorigenesis in Chemoresistant Osteosarcoma Cells.
    Cancer Res. 2019;79:3088-3099.
    PubMed     Abstract available

  80. KONCAR RF, Dey BR, Stanton AJ, Agrawal N, et al
    Identification of novel RAS signaling therapeutic vulnerabilities in Diffuse Intrinsic Pontine Gliomas.
    Cancer Res. 2019 Jun 14. pii: 0008-5472.CAN-18-3521.
    PubMed     Abstract available

    May 2019
  81. SHEN M, Dong C, Ruan X, Yan W, et al
    Chemotherapy-induced extracellular vesicle miRNAs promote breast cancer stemness by targeting ONECUT2.
    Cancer Res. 2019 May 22. pii: 0008-5472.CAN-18-4055.
    PubMed     Abstract available

  82. KAO SH, Cheng WC, Wang YT, Wu HT, et al
    Regulation of miRNA Biogenesis and Histone Modification by K63-Polyubiquitinated DDX17 Controls Cancer Stem-like Features.
    Cancer Res. 2019;79:2549-2563.
    PubMed     Abstract available

  83. TODOROVA PK, Fletcher-Sananikone E, Mukherjee B, Kollipara R, et al
    Radiation-induced DNA damage cooperates with heterozygosity of TP53 and PTEN to generate high grade gliomas.
    Cancer Res. 2019 May 14. pii: 0008-5472.CAN-19-0680.
    PubMed     Abstract available

  84. SONG M, Ping Y, Zhang K, Yang L, et al
    Low-dose IFN-gamma induces tumor cell stemness in the tumor microenvironment of non-small cell lung cancer.
    Cancer Res. 2019 May 13. pii: 0008-5472.CAN-19-0596.
    PubMed     Abstract available

  85. BOISE LH, Shanmugam M
    Stromal Support of Metabolic Function through Mitochondrial Transfer in Multiple Myeloma.
    Cancer Res. 2019;79:2102-2103.
    PubMed     Abstract available

  86. WANG J, Merino DM, Light N, Murphy BL, et al
    Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma.
    Cancer Res. 2019;79:2208-2219.
    PubMed     Abstract available

  87. VALETA-MAGARA A, Gadi A, Volta V, Walters B, et al
    Inflammatory Breast Cancer Promotes Development of M2 Tumor-associated Macrophages and Cancer Mesenchymal Cells Through a Complex Cytokine Network.
    Cancer Res. 2019 May 1. pii: 0008-5472.CAN-17-2158.
    PubMed     Abstract available

    April 2019
  88. HANSEN LJ, Sun R, Yang R, Singh SX, et al
    MTAP loss promotes stemness in glioblastoma and confers unique susceptibility to purine starvation.
    Cancer Res. 2019 Apr 30. pii: 0008-5472.CAN-18-1010.
    PubMed     Abstract available

  89. SHIDAL C, Singh NP, Nagarkatti P, Nagarkatti M, et al
    MicroRNA-92 expression in CD133+ melanoma stem cells regulates immunosuppression in the tumor microenvironment via integrin-dependent activation of TGF-beta.
    Cancer Res. 2019 Apr 23. pii: 0008-5472.CAN-18-2659.
    PubMed     Abstract available

  90. COLOMBO MP, Lecis D
    When Failure Is Worse Than Giving Up: The Case of CTL.
    Cancer Res. 2019;79:1753-1755.
    PubMed     Abstract available

  91. WANG D, Li W, Zhao R, Chen L, et al
    Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.
    Cancer Res. 2019;79:1769-1783.
    PubMed     Abstract available

  92. BUSHNELL GG, Hardas TP, Hartfield RM, Zhang Y, et al
    Biomaterial Scaffolds Recruit an Aggressive Population of Metastatic Tumor Cells In Vivo.
    Cancer Res. 2019;79:2042-2053.
    PubMed     Abstract available

  93. JIANG Y, Song Y, Wang R, Hu T, et al
    NFAT1-mediated regulation of NDEL1 promotes growth and invasion of glioma stem-like cells.
    Cancer Res. 2019 Apr 2. pii: 0008-5472.CAN-18-3297.
    PubMed     Abstract available

  94. DANG N, Lin Y, Rutgeerts O, Sagaert X, et al
    Solid tumor-induced immune regulation alters the GvHD/GvT paradigm after allogenic bone marrow transplantation.
    Cancer Res. 2019 Apr 1. pii: 0008-5472.CAN-18-3143.
    PubMed     Abstract available

    March 2019
  95. SRIVASTAVA AK, Banerjee A, Cui T, Han C, et al
    Inhibition of miR-328-3p impairs cancer stem cell function and prevents metastasis in ovarian cancer.
    Cancer Res. 2019 Mar 20. pii: 0008-5472.CAN-18-3668.
    PubMed     Abstract available

  96. HOFFMAN M, Gillmor A, Kunz DJ, Johnston MJ, et al
    Intratumoral genetic and functional heterogeneity in pediatric glioblastoma.
    Cancer Res. 2019 Mar 15. pii: 0008-5472.CAN-18-3441.
    PubMed     Abstract available

  97. LIU C, Banister CE, Buckhaults PJ
    Spindle assembly checkpoint inhibition can resensitize p53-null stem cells to cancer chemotherapy.
    Cancer Res. 2019 Mar 12. pii: 0008-5472.CAN-18-3024.
    PubMed     Abstract available

  98. TAO R, Murad N, Xu Z, Zhang P, et al
    MYC drives Group 3 medulloblastoma through transformation of Sox2+ astrocyte progenitor cells.
    Cancer Res. 2019 Mar 12. pii: 0008-5472.CAN-18-1787.
    PubMed     Abstract available

  99. TAKAI A, Dang H, Oishi N, Khatib S, et al
    Genome-wide RNAi Screen identifies PMPCB as a therapeutic vulnerability in EpCAM+ hepatocellular carcinoma.
    Cancer Res. 2019 Mar 12. pii: 0008-5472.CAN-18-3015.
    PubMed     Abstract available

  100. FEKIR K, Dubois-Pot-Schneider H, Desert R, Daniel Y, et al
    Retrodifferentiation of human tumor hepatocytes to stem cells leads to metabolic reprogramming and chemoresistance.
    Cancer Res. 2019 Mar 5. pii: 0008-5472.CAN-18-2110.
    PubMed     Abstract available

  101. BECKMANN PJ, Larson JD, Larsson AT, Ostergaard JP, et al
    Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.
    Cancer Res. 2019;79:905-917.
    PubMed     Abstract available

    February 2019
  102. BHOLA NE, Jansen VM, Koch JP, Li H, et al
    Correction: Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population.
    Cancer Res. 2019;79:875.

  103. TAKEDA M, Koseki J, Takahashi H, Miyoshi N, et al
    Disruption of endolysosomal RAB5/7 efficiently eliminates colorectal cancer stem cells.
    Cancer Res. 2019 Feb 14. pii: 0008-5472.CAN-18-2192.
    PubMed     Abstract available

    January 2019
  104. STEIN RG, Ebert S, Schlahsa L, Scholz CJ, et al
    Cognate Non-Lytic Interactions between CD8+ T cells and Breast Cancer Cells Induce Cancer Stem Cell-like Properties.
    Cancer Res. 2019 Jan 28. pii: 0008-5472.CAN-18-0387.
    PubMed     Abstract available

  105. PARK HK, Hong JH, Oh YT, Kim SS, et al
    Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells.
    Cancer Res. 2019 Jan 25. pii: 0008-5472.CAN-18-2558.
    PubMed     Abstract available

  106. CARTER BZ, Mak PY, Wang X, Tao W, et al
    An ARC-regulated IL1beta/Cox-2/PGE2/beta-catenin/ARC circuit controls leukemia-microenvironment interactions and confers drug resistance in AML.
    Cancer Res. 2019 Jan 23. pii: 0008-5472.CAN-18-0921.
    PubMed     Abstract available

  107. SUN T, Patil R, Galstyan A, Klymyshyn D, et al
    Blockade of a laminin-411 - Notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment crosstalk.
    Cancer Res. 2019 Jan 18. pii: 0008-5472.CAN-18-2725.
    PubMed     Abstract available

  108. AL SAYED MF, Amrein MA, Buhrer ED, Huguenin AL, et al
    T-cell-Secreted TNFalpha Induces Emergency Myelopoiesis and Myeloid-Derived Suppressor Cell Differentiation in Cancer.
    Cancer Res. 2019;79:346-359.
    PubMed     Abstract available

  109. VUMMIDI GIRIDHAR P, Williams K, VonHandorf AP, Deford PL, et al
    Constant Degradation of the Androgen Receptor by MDM2 Conserves Prostate Cancer Stem Cell Integrity.
    Cancer Res. 2019 Jan 9. pii: 0008-5472.CAN-18-1753.
    PubMed     Abstract available

  110. OLIPHANT MUJ, Vincent MY, Galbraith MD, Pandey A, et al
    Six2 mediates late-stage metastasis via direct regulation of Sox2 and induction of a cancer stem cell program.
    Cancer Res. 2019 Jan 3. pii: 0008-5472.CAN-18-1791.
    PubMed     Abstract available

  111. HU T, Chong Y, Lu S, Qin H, et al
    Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice.
    Cancer Res. 2019;79:114-124.
    PubMed     Abstract available

    December 2018
  112. GU Y, Wei X, Sun Y, Gao H, et al
    miR-192-5p silencing by genetic aberrations is a key event in hepatocellular carcinomas with cancer stem cell features.
    Cancer Res. 2018 Dec 7. pii: 0008-5472.CAN-18-1675.
    PubMed     Abstract available

  113. WARDA W, Larosa F, Neto Da Rocha M, Trad R, et al
    CML hematopoietic stem cells expressing IL-1RAP can be targeted by chimeric antigen receptor (CAR)-engineered T cells.
    Cancer Res. 2018 Dec 4. pii: 0008-5472.CAN-18-1078.
    PubMed     Abstract available

    November 2018
  114. MORGAN MA, Canman CE
    Replication Stress: An Achilles' Heel of Glioma Cancer Stem-like Cells.
    Cancer Res. 2018 Nov 29. pii: 0008-5472.CAN-18-2439.
    PubMed     Abstract available

  115. BU W, Liu Z, Jiang W, Nagi C, et al
    Mammary precancerous stem and non-stem cells evolve into cancers of distinct subtypes.
    Cancer Res. 2018 Nov 6. pii: 0008-5472.CAN-18-1087.
    PubMed     Abstract available

    October 2018
  116. CHOI M, Yu SJ, Choi Y, Lee HR, et al
    Polymer thin film-induced tumor spheroids acquire cancer stem cell-like properties.
    Cancer Res. 2018 Oct 23. pii: 0008-5472.CAN-18-0927.
    PubMed     Abstract available

  117. LIU T, Xu H, Huang M, Ma W, et al
    Circulating glioma cells exhibit stem cell-like properties.
    Cancer Res. 2018 Oct 15. pii: 0008-5472.CAN-18-0650.
    PubMed     Abstract available

  118. RAVINDRAN MENON D, Luo Y, Arcaroli JJ, Liu S, et al
    CDK1 interacts with Sox2 and promotes tumor initiation in human melanoma.
    Cancer Res. 2018 Oct 8. pii: 0008-5472.CAN-18-0330.
    PubMed     Abstract available

    September 2018
  119. VAN LIDTH DE JEUDE JF, Spaan CN, Meijer BJ, Smit WL, et al
    Heterozygosity of chaperone Grp78 reduces intestinal stem cell regeneration potential and protects against adenoma formation.
    Cancer Res. 2018 Sep 19. pii: 0008-5472.CAN-17-3600.
    PubMed     Abstract available

  120. CHEN C, Okita Y, Watanabe Y, Abe F, et al
    Glycoprotein nmb is exposed on the surface of dormant breast cancer cells and induces stem cell-like properties.
    Cancer Res. 2018 Sep 17. pii: 0008-5472.CAN-18-0599.
    PubMed     Abstract available

    August 2018
  121. KOIFMAN G, Shetzer Y, Eizenberger S, Solomon H, et al
    A mutant p53-dependent embryonic stem cell gene signature is associated with augmented tumorigenesis of stem cells.
    Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0805.
    PubMed     Abstract available

  122. HOGSTROM J, Heino S, Kallio P, Lahde M, et al
    Transcription factor PROX1 suppresses Notch pathway activation via the nucleosome remodeling and deacetylase complex in colorectal cancer stem-like cells.
    Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0451.
    PubMed     Abstract available

  123. HILLER B, Hoppe A, Haase C, Hiller C, et al
    Ribonucleotide excision repair is essential to prevent squamous cell carcinoma of the skin.
    Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-1099.
    PubMed     Abstract available

  124. BAYLEY R, Blakemore D, Cancian L, Dumon S, et al
    MYBL2 supports DNA double strand break repair in haematopoietic stem cells.
    Cancer Res. 2018 Aug 6. pii: 0008-5472.CAN-18-0273.
    PubMed     Abstract available

    July 2018
  125. UBELLACKER JM, Baryawno N, Severe N, DeCristo MJ, et al
    Modulating bone marrow hematopoietic lineage potential to prevent bone metastasis in breast cancer.
    Cancer Res. 2018 Jul 31. pii: 0008-5472.CAN-18-0548.
    PubMed     Abstract available

  126. CARRUTHERS RD, Ahmed SU, Ramachandran S, Strathdee K, et al
    Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells.
    Cancer Res. 2018 Jul 5. pii: 0008-5472.CAN-18-0569.
    PubMed     Abstract available

    June 2018
  127. QAZI MA, Vora P, Venugopal C, Adams J, et al
    Co-targeting ephrin receptor tyrosine kinases A2 and A3 in cancer stem cells reduces growth of recurrent glioblastoma.
    Cancer Res. 2018 Jun 26. pii: 0008-5472.CAN-18-0267.
    PubMed     Abstract available

  128. HIRST J, Pathak HB, Hyter S, Pessetto ZY, et al
    Licofelone enhances the efficacy of paclitaxel in ovarian cancer by reversing drug resistance and tumor stem-like properties.
    Cancer Res. 2018 Jun 11. pii: 0008-5472.CAN-17-3993.
    PubMed     Abstract available

  129. LU H, Tran L, Park Y, Chen I, et al
    Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF-1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment.
    Cancer Res. 2018 Jun 7. pii: 0008-5472.CAN-18-0270.
    PubMed     Abstract available

    May 2018
  130. ULLMANN P, Rodriguez F, Schmitz M, Meurer SK, et al
    The microRNA-371~373 cluster represses colon cancer initiation and metastatic colonization by inhibiting the TGFBR2/ID1 signaling axis.
    Cancer Res. 2018 May 10. pii: 0008-5472.CAN-17-3003.
    PubMed     Abstract available

  131. MATSUNAGA N, Ogino T, Hara Y, Tanaka T, et al
    Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase.
    Cancer Res. 2018 May 7. pii: 0008-5472.CAN-17-4034.
    PubMed     Abstract available

  132. HU T, Chong Y, Lu S, Wang R, et al
    MicroRNA 339 promotes development of Stem Cell Leukemia/Lymphoma syndrome via downregulation of the BCL2L11 and BAX pro-apoptotic genes.
    Cancer Res. 2018 May 7. pii: 0008-5472.CAN-17-4049.
    PubMed     Abstract available

    April 2018
  133. KAID C, Goulart E, Caires-Junior LC, Araujo BHS, et al
    Zika virus selectively kills aggressive human embryonal CNS tumor cells in vitro and in vivo.
    Cancer Res. 2018 Apr 26. pii: 0008-5472.CAN-17-3201.
    PubMed     Abstract available

  134. RESAR L, Chia L, Xian L
    Lessons from the Crypt: HMGA1-Amping up Wnt for Stem Cells and Tumor Progression.
    Cancer Res. 2018 Apr 4. pii: 0008-5472.CAN-17-3045.
    PubMed     Abstract available

  135. KIKUCHI J, Kuroda Y, Koyama D, Osada N, et al
    Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide.
    Cancer Res. 2018;78:1766-1778.
    PubMed     Abstract available

  136. SHEA MP, O'Leary KA, Fakhraldeen SA, Goffin V, et al
    Antiestrogen Therapy Increases Plasticity and Cancer Stemness of Prolactin-Induced ERalpha(+) Mammary Carcinomas.
    Cancer Res. 2018;78:1672-1684.
    PubMed     Abstract available

    March 2018
  137. REN D, Zhu X, Kong R, Zhao Z, et al
    Targeting Brain-Adaptive Cancer Stem Cells Prohibits Brain Metastatic Colonization of Triple-Negative Breast Cancer.
    Cancer Res. 2018 Mar 22. pii: 0008-5472.CAN-17-2994.
    PubMed     Abstract available

  138. HALL AW, Battenhouse AM, Shivram H, Morris AR, et al
    Bivalent chromatin domains in glioblastoma reveal a subtype-specific signature of glioma stem cells.
    Cancer Res. 2018 Mar 16. pii: 0008-5472.CAN-17-1724.
    PubMed     Abstract available

  139. CONDELLO S, Sima LE, Ivan C, Cardenas H, et al
    Tissue transglutaminase regulates interactions between ovarian cancer stem cells and the tumor niche.
    Cancer Res. 2018 Mar 6. pii: 0008-5472.CAN-17-2319.
    PubMed     Abstract available

  140. PAQUET-FIFIELD S, Koh SL, Cheng L, Beyit LM, et al
    Tight junction protein claudin-2 promotes self-renewal of human colorectal cancer stem-like cells.
    Cancer Res. 2018 Mar 6. pii: 0008-5472.CAN-17-1869.
    PubMed     Abstract available

  141. WANG H, Shepard MJ, Zhang C, Dong L, et al
    Deletion of the von Hippel-Lindau Gene in Hemangioblasts Causes Hemangioblastoma-like Lesions in Murine Retina.
    Cancer Res. 2018;78:1266-1274.
    PubMed     Abstract available

    February 2018
  142. SORRENTINO C, Ciummo SL, Cipollone G, Caputo S, et al
    Interleukin-30/IL-27p28 shapes prostate cancer stem-like cell behavior and is critical for tumor onset and metastasization.
    Cancer Res. 2018 Feb 27. pii: 0008-5472.CAN-17-3117.
    PubMed     Abstract available

  143. CHENG BY, Lau EY, Leung HW, Leung CO, et al
    IRAK1 augments cancer stemness and drug resistance via the AP-1/AKR1B10 signaling cascade in hepatocellular carcinoma.
    Cancer Res. 2018 Feb 26. pii: 0008-5472.CAN-17-2445.
    PubMed     Abstract available

  144. RIMKUS TK, Carpenter RL, Sirkisoon SR, Zhu D, et al
    Truncated glioma-associated oncogene homolog 1 (tGLI1) mediates mesenchymal glioblastoma via transcriptional activation of CD44.
    Cancer Res. 2018 Feb 20. pii: 0008-5472.CAN-17-2933.
    PubMed     Abstract available

  145. LIU C, Liu L, Chen X, Cheng J, et al
    LSD1 Stimulates Cancer-Associated Fibroblasts to Drive Notch3-Dependent Self-Renewal of Liver Cancer Stem-like Cells.
    Cancer Res. 2018;78:938-949.
    PubMed     Abstract available

  146. DE S, Lindner DJ, Coleman C, Wildey G, et al
    The FACT inhibitor CBL0137 synergizes with cisplatin in small cell lung cancer by increasing NOTCH1 expression and targeting tumor-initiating cells.
    Cancer Res. 2018 Feb 13. pii: 0008-5472.CAN-17-1920.
    PubMed     Abstract available

  147. JUNG Y, Cackowski FC, Yumoto K, Decker A, et al
    CXCL12gamma Promotes Development of Metastatic Castration Resistant Prostate Cancer by Induction of Cancer Stem Cell and Neuroendocrine Phenotypes.
    Cancer Res. 2018 Feb 5. pii: 0008-5472.CAN-17-2332.
    PubMed     Abstract available

    January 2018
  148. SANG Y, Li Y, Song L, Alvarez AA, et al
    TRIM59 promotes gliomagenesis by inhibiting TC45 dephosphorylation of STAT3.
    Cancer Res. 2018 Jan 31. pii: 0008-5472.CAN-17-2774.
    PubMed     Abstract available

  149. YAN TT, Ren LL, Shen CQ, Wang ZH, et al
    MicroRNA-508 defines the stem-like/mesenchymal subtype in colorectal cancer.
    Cancer Res. 2018 Jan 26. pii: 0008-5472.CAN-17-2101.
    PubMed     Abstract available

  150. JIAO X, Velasco-Velazquez MA, Wang M, Li Z, et al
    CCR5 governs DNA damage and breast cancer stem cell expansion.
    Cancer Res. 2018 Jan 22. pii: 0008-5472.CAN-17-0915.
    PubMed     Abstract available

  151. YANG Y, Leonard M, Zhang Y, Zhao D, et al
    HER2-Driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1.
    Cancer Res. 2018;78:422-435.
    PubMed     Abstract available

  152. LIU C, Nie D, Li J, Du X, et al
    Antitumor effects of blocking protein neddylation in T315I-BCR-ABL leukemia cells and leukemia stem cells.
    Cancer Res. 2018 Jan 10. pii: 0008-5472.CAN-17-1733.
    PubMed     Abstract available

  153. TIMANER M, Letko-Khait N, Kotsofruk R, Benguigui M, et al
    Therapy-educated mesenchymal stem cells enrich for tumor initiating cells.
    Cancer Res. 2018 Jan 4. pii: 0008-5472.CAN-17-1547.
    PubMed     Abstract available

  154. CARAMEL J, Ligier M, Puisieux A
    Pleiotropic Roles for ZEB1 in Cancer.
    Cancer Res. 2018;78:30-35.
    PubMed     Abstract available

  155. OOKI A, Del Carmen Rodriguez Pena M, Marchionni L, Dinalankara W, et al
    YAP1 and COX2 Coordinately Regulate Urothelial Cancer Stem-like Cells.
    Cancer Res. 2018;78:168-181.
    PubMed     Abstract available

  156. ROSSNAGL S, Ghura H, Groth C, Altrock E, et al
    A Subpopulation of Stromal Cells Controls Cancer Cell Homing to the Bone Marrow.
    Cancer Res. 2018;78:129-142.
    PubMed     Abstract available

    December 2017
  157. MAEDA T, Hiraki M, Jin C, Rajabi H, et al
    MUC1-C Induces PD-L1 and Immune Evasion in Triple-Negative Breast Cancer.
    Cancer Res. 2017 Dec 20. pii: 0008-5472.CAN-17-1636.
    PubMed     Abstract available

  158. BROCK A, Huang S
    Precision Oncology: Between Vaguely Right and Precisely Wrong.
    Cancer Res. 2017;77:6473-6479.
    PubMed     Abstract available

    November 2017
  159. HOU P, Li L, Chen F, Chen Y, et al
    PTBP3-mediated regulation of ZEB1 mRNA stability promotes epithelial-mesenchymal transition in breast cancer.
    Cancer Res. 2017 Nov 29. pii: 0008-5472.CAN-17-0883.
    PubMed     Abstract available

  160. HUANG WY, Lai SF, Chiu HY, Chang M, et al
    Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy.
    Cancer Res. 2017;77:6083-6096.
    PubMed     Abstract available

  161. CHIBA Y, Mizoguchi I, Furusawa J, Hasegawa H, et al
    Interleukin-27 Exerts Its Antitumor Effects by Promoting Differentiation of Hematopoietic Stem Cells to M1 Macrophages.
    Cancer Res. 2017 Nov 1. pii: canres.0960.2017.
    PubMed     Abstract available

  162. SERVIDEI T, Meco D, Muto V, Bruselles A, et al
    Novel SEC61G-EGFR Fusion Gene in Pediatric Ependymomas Discovered by Clonal Expansion of Stem Cells in Absence of Exogenous Mitogens.
    Cancer Res. 2017;77:5860-5872.
    PubMed     Abstract available

  163. ISHIGAKI H, Maeda T, Inoue H, Akagi T, et al
    Transplantation of iPS-Derived Tumor Cells with a Homozygous MHC Haplotype Induces GRP94 Antibody Production in MHC-Matched Macaques.
    Cancer Res. 2017;77:6001-6010.
    PubMed     Abstract available

    October 2017
  164. HOUSE CD, Jordan E, Hernandez L, Ozaki M, et al
    NF-kB promotes ovarian tumorigenesis via classical pathways supporting proliferative cancer cells and alternative pathways supporting ALDH+ cancer stem-like cells.
    Cancer Res. 2017 Oct 26. pii: canres.0366.2017.
    PubMed     Abstract available

  165. LI Y, Zhong C, Liu D, Yu W, et al
    Evidence for Kaposi's Sarcoma originating from Mesenchymal Stem Cell through KSHV-induced Mesenchymal-to-Endothelial Transition.
    Cancer Res. 2017 Oct 24. pii: canres.1961.2017.
    PubMed     Abstract available

    September 2017
  166. ISHIHARA S, Inman DR, Li WJ, Ponik SM, et al
    Mechano-signal transduction in mesenchymal stem cells induces prosaposin secretion to drive the proliferation of breast cancer cells.
    Cancer Res. 2017 Sep 28. pii: canres.0569.2017.
    PubMed     Abstract available

  167. DE GRANDIS M, Bardin F, Fauriat C, Zemmour C, et al
    JAM-C identifies Src family kinase-activated leukemia-initiating cells and predicts poor prognosis in acute myeloid leukemia.
    Cancer Res. 2017 Sep 28. pii: canres.1223.2017.
    PubMed     Abstract available

  168. KIDDER BL, He R, Wangsa D, Padilla-Nash HM, et al
    SMYD5 controls heterochromatin and chromosome integrity during embryonic stem cell differentiation.
    Cancer Res. 2017 Sep 26. pii: canres.0828.2017.
    PubMed     Abstract available

  169. MATSUMOTO T, Takai A, Eso Y, Kinoshita K, et al
    Proliferating EpCAM-positive ductal cells in the inflamed liver give rise to hepatocellular carcinoma.
    Cancer Res. 2017 Sep 26. pii: canres.1800.2017.
    PubMed     Abstract available

  170. YANG A, Qin S, Schulte BA, Ethier SP, et al
    MYC Inhibition depletes cancer stem-like cells in triple-negative breast cancer.
    Cancer Res. 2017 Sep 26. pii: canres.3452.2016.
    PubMed     Abstract available

  171. YAN X, Zhang D, Wu W, Wu S, et al
    Mesenchymal stem cells promote hepatocarcinogenesis via lncRNA-MUF interaction with ANXA2 and miR-34a.
    Cancer Res. 2017 Sep 25. pii: canres.1915.2017.
    PubMed     Abstract available

  172. YANG R, Chen LH, Hansen LJ, Carpenter AB, et al
    Cic loss promotes gliomagenesis via aberrant neural stem cell proliferation and differentiation.
    Cancer Res. 2017 Sep 22. pii: canres.1018.2017.
    PubMed     Abstract available

  173. SHUKLA V, Rao M, Zhang H, Beers J, et al
    ASXL3 is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer.
    Cancer Res. 2017 Sep 21. pii: canres.0570.2017.
    PubMed     Abstract available

  174. DASHZEVEG NK, Taftaf R, Ramos EK, Torre-Healy L, et al
    New Advances and Challenges of Targeting Cancer Stem Cells.
    Cancer Res. 2017 Sep 19. doi: 10.1158/0008-5472.CAN-17-0054.
    PubMed     Abstract available

  175. SONG KH, Choi CH, Lee HJ, Oh SJ, et al
    HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells.
    Cancer Res. 2017;77:5039-5053.
    PubMed     Abstract available

  176. BORRIELLO L, Nakata R, Sheard MA, Fernandez GE, et al
    Cancer-Associated Fibroblasts Share Characteristics and Protumorigenic Activity with Mesenchymal Stromal Cells.
    Cancer Res. 2017;77:5142-5157.
    PubMed     Abstract available

  177. BHAGAT TD, Chen S, Bartenstein M, Barlowe AT, et al
    Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/beta-Catenin Activation.
    Cancer Res. 2017;77:4846-4857.
    PubMed     Abstract available

  178. METZGER E, Stepputtis SS, Strietz J, Preca BT, et al
    KDM4 inhibition targets breast cancer stem-like cells.
    Cancer Res. 2017 Sep 7. pii: canres.1754.2017.
    PubMed     Abstract available

    August 2017
  179. YANG F, Wei J, Zhang S, Zhang X, et al
    Shrimp miR-S8 suppresses the stemness of human melanoma stem-like cells by targeting the transcription factor YB-1.
    Cancer Res. 2017 Aug 30. pii: canres.1375.2017.
    PubMed     Abstract available

  180. JIN L, Vu T, Yuan G, Datta PK, et al
    STRAP promotes stemness of human colorectal cancer via epigenetic regulation of the NOTCH pathway.
    Cancer Res. 2017 Aug 21. pii: canres.0286.2017.
    PubMed     Abstract available

  181. DODD RD, Lee CL, Overton T, Huang W, et al
    NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response.
    Cancer Res. 2017;77:4486-4497.
    PubMed     Abstract available

  182. ROHIRA AD, Yan F, Wang L, Wang J, et al
    Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells.
    Cancer Res. 2017;77:4293-4304.
    PubMed     Abstract available

    July 2017
  183. REGGIANI F, Labanca V, Mancuso P, Rabascio C, et al
    Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression.
    Cancer Res. 2017 Jul 28. pii: canres.0914.2017.
    PubMed     Abstract available

  184. WANG X, Huang Z, Wu Q, Prager BC, et al
    MYC-regulated Mevalonate Metabolism Maintains Brain Tumor Initiating Cells.
    Cancer Res. 2017 Jul 20. pii: canres.0114.2017.
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    June 2017
  185. HOU PC, Li YH, Lin SC, Lin SC, et al
    Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness.
    Cancer Res. 2017 Jun 26. pii: canres.2990.2016.
    PubMed     Abstract available

  186. RODRIGUEZ-HERNANDEZ G, Hauer J, Martin-Lorenzo A, Schafer D, et al
    Infection exposure promotes ETV6-RUNX1 precursor B cell leukemia via impaired H3K4 demethylases.
    Cancer Res. 2017 Jun 19. pii: canres.0701.2017.
    PubMed     Abstract available

    May 2017
  187. YAN H, Romero-Lopez M, Benitez LI, Di K, et al
    3D mathematical modeling of glioblastoma suggests that transdifferentiated vascular endothelial cells mediate resistance to current standard-of-care therapy.
    Cancer Res. 2017 May 23. pii: canres.3094.2016.
    PubMed     Abstract available

  188. TECH K, Tikunov AP, Farooq H, Morrissy AS, et al
    Pyruvate kinase inhibits proliferation during postnatal cerebellar neurogenesis and suppresses medulloblastoma formation.
    Cancer Res. 2017 May 17. pii: canres.3304.2016.
    PubMed     Abstract available

  189. RODRIGUEZ-BRENES IA, Kurtova AV, Lin C, Lee YC, et al
    Cellular Hierarchy as a Determinant of Tumor Sensitivity to Chemotherapy.
    Cancer Res. 2017;77:2231-2241.
    PubMed     Abstract available

    April 2017
  190. WANG D, Sun H, Wei J, Cen B, et al
    CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer.
    Cancer Res. 2017 Apr 28. pii: canres.3199.2016.
    PubMed     Abstract available

  191. JARIWALA N, Rajasekaran D, Mendoza RG, Shen XN, et al
    Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma.
    Cancer Res. 2017 Apr 20. pii: canres.0298.2017.
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  192. SARKAR S, Mirzaei R, Zemp FJ, Wu W, et al
    Activation of NOTCH signaling by tenascin-C promotes growth of human brain tumor-initiating cells.
    Cancer Res. 2017 Apr 17. pii: canres.2171.2016.
    PubMed     Abstract available

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