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  Stem Cell Research

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Articles published in Biomaterials

Retrieve available abstracts of 90 articles:
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Single Articles


    October 2025
  1. YUAN M, Yin Z, Wang Z, Xiong Z, et al
    Modification of MSCs with aHSCs-targeting peptide pPB for enhanced therapeutic efficacy in liver fibrosis.
    Biomaterials. 2025;321:123295.
    PubMed     Abstract available


    September 2025
  2. ESMAEILI H, Zhang Y, Ravi K, Neff K, et al
    Development of an electroconductive Heart-on-a-chip model to investigate cellular and molecular response of human cardiac tissue to gold nanomaterials.
    Biomaterials. 2025;320:123275.
    PubMed     Abstract available


  3. YANG P, Chen X, Qin Y, Yu L, et al
    Regulation of osteoimmune microenvironment via functional dynamic hydrogel for diabetic bone regeneration.
    Biomaterials. 2025;320:123273.
    PubMed     Abstract available


  4. CHEN TY, Xu J, Tai CH, Wen TK, et al
    Biodegradable, electroconductive self-healing hydrogel based on polydopamine-coated polyurethane nano-crosslinker for Parkinson's disease therapy.
    Biomaterials. 2025;320:123268.
    PubMed     Abstract available


  5. LU J, Li Y, Cai J, Jin X, et al
    Biocompatibility and therapeutic efficacy of crosslinked hydrogel filled 3D-printed nerve conduit for sacral nerve injury repair.
    Biomaterials. 2025;320:123230.
    PubMed     Abstract available


    August 2025
  6. ZHANG N, Gao M, Hu X, Wang P, et al
    Biomimetic peroxisome targets myocardial injury and promotes heart repair and regeneration.
    Biomaterials. 2025;319:123214.
    PubMed     Abstract available


  7. ZHANG W, Liu Y, Wu Y, Wang Z, et al
    ROS-triggered biomimetic hydrogel soft scaffold for ischemic stroke repair.
    Biomaterials. 2025;319:123217.
    PubMed     Abstract available


  8. YANG Q, Zhou J, Yang M, Wei J, et al
    A Di-aptamer-functionalized scaffold promotes bone regeneration by facilitating the selective retention of MSCs and EPCs and then promoting crosstalk between osteogenesis and angiogenesis.
    Biomaterials. 2025;319:123197.
    PubMed     Abstract available


    July 2025
  9. WANG B, Zhang Q, Liu C, Chen X, et al
    Counteracting immunodepression by extracellular matrix hydrogel to promote brain tissue remodeling and neurological function recovery after traumatic brain injury.
    Biomaterials. 2025;318:123181.
    PubMed     Abstract available


  10. ROSHANBINFAR K, Evans AD, Samanta S, Kolesnik-Gray M, et al
    Enhancing biofabrication: Shrink-resistant collagen-hyaluronan composite hydrogel for tissue engineering and 3D bioprinting applications.
    Biomaterials. 2025;318:123174.
    PubMed     Abstract available


  11. ANTICH C, Kundu S, Frebert S, Voss T, et al
    Bioprinting spatially guided functional 3D neural circuits with agarose-xanthan gum copolymer hydrogels.
    Biomaterials. 2025;318:123156.
    PubMed     Abstract available


  12. BING J, Zhou B, Chen M, Shen Y, et al
    Nanomedicine-enabled concurrent regulations of ROS generation and copper metabolism for sonodynamic-amplified tumor therapy.
    Biomaterials. 2025;318:123137.
    PubMed     Abstract available


    June 2025
  13. FORGHANI P, Liu W, Wang Z, Ling Z, et al
    Spaceflight alters protein levels and gene expression associated with stress response and metabolic characteristics in human cardiac spheroids.
    Biomaterials. 2025;317:123080.
    PubMed     Abstract available


  14. ANDROULIDAKIS C, Svitina H, Ioannidis K, Dunn AR, et al
    Cartilaginous microtissues exhibit extreme resilience under compression with size-dependent mechanical properties.
    Biomaterials. 2025;317:123074.
    PubMed     Abstract available


  15. ZHU H, Liu F, Liao Y, Li H, et al
    Biomimetic nanostructural materials based on placental amniotic membrane-derived nanofibers for self-healing and anti-adhesion during cesarean section.
    Biomaterials. 2025;317:123081.
    PubMed     Abstract available


  16. JIN F, Wei X, Liu Y, Tang L, et al
    Engineered cell membrane vesicles loaded with lysosomophilic drug for acute myeloid leukemia therapy via organ-cell-organelle cascade-targeting.
    Biomaterials. 2025;317:123091.
    PubMed     Abstract available


  17. LIU C, Yu B, Zhang Z, Su L, et al
    LIPUS activated piezoelectric pPLLA/SrSiO(3) composite scaffold promotes osteochondral regeneration through P2RX1 mediated Ca(2+) signaling pathway.
    Biomaterials. 2025;317:123084.
    PubMed     Abstract available


  18. YANG Y, Xu Z, He S, Wang C, et al
    Developmental dynamics mimicking inversely engineered pericellular matrix for articular cartilage regeneration.
    Biomaterials. 2025;317:123066.
    PubMed     Abstract available


  19. XING X, Gong Z, Chen C, Lin Y, et al
    Injectable bioresponsive bone adhesive hydrogels inhibit NLRP3 inflammasome on demand to accelerate diabetic fracture healing.
    Biomaterials. 2025;317:123059.
    PubMed     Abstract available


    May 2025
  20. YAO X, Yang H, Guo S, Liu Y, et al
    Radiation-triggerable bioreactors enable bioenergetic reprograming of cancer stem cell plasticity via targeted arginine metabolism disruption for augmented radio-immunotherapy.
    Biomaterials. 2025;322:123391.
    PubMed     Abstract available


  21. DAI Z, Yu Y, Chen R, Zhu H, et al
    Selenium promotes neural development through the regulation of GPX4 and SEPP1 in an iPSC-derived neuronal model.
    Biomaterials. 2025;316:123011.
    PubMed     Abstract available


  22. CHOI M, Al Fahad MA, Shanto PC, Park SS, et al
    Surface modification of decellularized kidney scaffold with chemokine and AKI-CKD cytokine juice to increase the recellularization efficiency of bio-engineered kidney.
    Biomaterials. 2025;316:123007.
    PubMed     Abstract available


  23. CHEN H, Wang W, Yang Y, Zhang B, et al
    A sequential stimuli-responsive hydrogel promotes structural and functional recovery of severe spinal cord injury.
    Biomaterials. 2025;316:122995.
    PubMed     Abstract available


  24. DUTTA SD, Hexiu J, Moniruzzaman M, Patil TV, et al
    Tailoring osteoimmunity and hemostasis using 3D-Printed nano-photocatalytic bactericidal scaffold for augmented bone regeneration.
    Biomaterials. 2025;316:122991.
    PubMed     Abstract available


  25. SUN H, Zhan M, Zou Y, Ma J, et al
    Bioactive phosphorus dendrimers deliver protein/drug to tackle osteoarthritis via cooperative macrophage reprogramming.
    Biomaterials. 2025;316:122999.
    PubMed     Abstract available


  26. WU L, Xu T, Li S, Sun K, et al
    Sequential activation of osteogenic microenvironment via composite peptide-modified microfluidic microspheres for promoting bone regeneration.
    Biomaterials. 2025;316:122974.
    PubMed     Abstract available


    April 2025
  27. SONG H, Du X, Zhang Y, Liu W, et al
    Gelatin sponge patch grafting of microcryogel-based three-dimensional mesenchymal stem cells to alleviate acute liver failure.
    Biomaterials. 2025;321:123324.
    PubMed     Abstract available


  28. KAO YC, Yang PC, Lin YP, Chen GH, et al
    Tailoring the therapeutic potential of stem cell spheroid-derived decellularized ECM through post-decellularization BDNF incorporation to enhance brain repair.
    Biomaterials. 2025;321:123332.
    PubMed     Abstract available


  29. CHEN S, Wang W, Shen L, Liu H, et al
    A 3D-printed microdevice encapsulates vascularized islets composed of iPSC-derived beta-like cells and microvascular fragments for type 1 diabetes treatment.
    Biomaterials. 2025;315:122947.
    PubMed     Abstract available


  30. GAO S, Liu M, Zhang Y, He Z, et al
    A precision intelligent nanomissile for inhibiting tumor metastasis, boosting energy deprivation and immunotherapy.
    Biomaterials. 2025;315:122953.
    PubMed     Abstract available


  31. ZHAO B, Wang C, Sun M, Ma X, et al
    UC-MSCs based on biomimetic microniche exert excellent regulatory effects on acute brain inflammation through advantageous properties.
    Biomaterials. 2025;315:122945.
    PubMed     Abstract available


  32. CHEN GH, Sia KC, Liu SW, Kao YC, et al
    Implantation of MSC spheroid-derived 3D decellularized ECM enriched with the MSC secretome ameliorates traumatic brain injury and promotes brain repair.
    Biomaterials. 2025;315:122941.
    PubMed     Abstract available


    March 2025
  33. PARK N, Kim KS, Lee S, Choi JH, et al
    Enhanced stem cell-mediated therapeutic immune modulation with zinc oxide nanoparticles in liver regenerative therapy.
    Biomaterials. 2025;320:123232.
    PubMed     Abstract available


  34. XU Z, Song R, Chen Z, Sun Y, et al
    Hydrogen generators-protected mesenchymal stem cells reverse articular redox imbalance-induced immune dysfunction for osteoarthritis treatment.
    Biomaterials. 2025;320:123239.
    PubMed     Abstract available


  35. ZHAO F, Jia Z, Zhang L, Liu G, et al
    A MnO(2) nanosheets doping double crosslinked hydrogel for cartilage defect repair through alleviating inflammation and guiding chondrogenic differentiation.
    Biomaterials. 2025;314:122875.
    PubMed     Abstract available


  36. LI H, Ma L, Zhu N, Liang X, et al
    Mesenchymal stromal cells surface engineering for efficient hematopoietic reconstitution.
    Biomaterials. 2025;314:122882.
    PubMed     Abstract available


  37. LAM W, Yao Y, Tang C, Wang Y, et al
    Bifunctional mesoporous HMUiO-66-NH(2) nanoparticles for bone remodeling and ROS scavenging in periodontitis therapy.
    Biomaterials. 2025;314:122872.
    PubMed     Abstract available


  38. PANG X, Zhang T, Li J, Yu L, et al
    LDH nanoparticles-doped cellulose nanofiber scaffolds with aligned microchannels direct high-efficiency neural regeneration and organized neural circuit remodeling through RhoA/Rock/Myosin II pathway.
    Biomaterials. 2025;314:122873.
    PubMed     Abstract available


  39. TABE S, Takeuchi K, Aoshima K, Okumura A, et al
    A pancreatic cancer organoid incorporating macrophages reveals the correlation between the diversity of tumor-associated macrophages and cancer cell survival.
    Biomaterials. 2025;314:122838.
    PubMed     Abstract available


  40. BEZOLD MG, Dollinger BR, DeJulius CR, Keech MC, et al
    Shear-thinning hydrogel for allograft cell transplantation and externally controlled transgene expression.
    Biomaterials. 2025;314:122812.
    PubMed     Abstract available


  41. NIU R, Xin Q, Lao J, Huang X, et al
    Topological polymeric glucosyl nanoaggregates in scaffold enable high-density piscine muscle tissue.
    Biomaterials. 2025;314:122819.
    PubMed     Abstract available


  42. LETKO KHAIT N, Zuccaro S, Abdo D, Cui H, et al
    Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain.
    Biomaterials. 2025;314:122818.
    PubMed     Abstract available


  43. MENG J, Lu J, Jiang C, Deng L, et al
    Collagen hydrogel-driven pyroptosis suppression and combined microfracture technique delay osteoarthritis progression.
    Biomaterials. 2025;314:122817.
    PubMed     Abstract available


    February 2025
  44. DU J, Zhen G, Chen H, Zhang S, et al
    Corrigendum to 'Optimal electrical stimulation boosts stem cell therapy in nerve regeneration' [Biomaterials 181 (2018) 18758].
    Biomaterials. 2025 Feb 21:123172. doi: 10.1016/j.biomaterials.2025.123172.
    PubMed    


  45. KIM SH, Kim CH, Lee CH, Lee J, et al
    Glycoengineered stem cell-derived extracellular vesicles for targeted therapy of acute kidney injury.
    Biomaterials. 2025;318:123165.
    PubMed     Abstract available


  46. MOHSENI SO, Au KM, Issa W, Ruan L, et al
    Multiple sclerosis treatments a review of current biomedical engineering approaches.
    Biomaterials. 2025;313:122807.
    PubMed     Abstract available


  47. WANG Z, Chen J, Wang J, Xu M, et al
    MSCs biomimetic ultrasonic phase change nanoparticles promotes cardiac functional recovery after acute myocardial infarction.
    Biomaterials. 2025;313:122775.
    PubMed     Abstract available


  48. LIU B, Lv M, Duan Y, Lin J, et al
    Genetically engineered CD276-anchoring biomimetic nanovesicles target senescent escaped tumor cells to overcome chemoresistant and immunosuppressive breast cancer.
    Biomaterials. 2025;313:122796.
    PubMed     Abstract available


  49. SHE JW, Young CM, Chou SJ, Wu YR, et al
    Gradient conducting polymer surfaces with netrin-1-conjugation promote axon guidance and neuron transmission of human iPSC-derived retinal ganglion cells.
    Biomaterials. 2025;313:122770.
    PubMed     Abstract available


  50. SIMON L, Constanzo J, Terraza-Aguirre C, Ibn Elfekih Z, et al
    Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation.
    Biomaterials. 2025;313:122748.
    PubMed     Abstract available


  51. LI Y, Li J, Zhong Y, Zhang Q, et al
    pH-responsive and nanoenzyme-loaded artificial nanocells relieved osteomyelitis efficiently by synergistic chemodynamic and cuproptosis therapy.
    Biomaterials. 2025;313:122762.
    PubMed     Abstract available


    January 2025
  52. INUI J, Ueyama-Toba Y, Imamura C, Nagai W, et al
    Two-dimensionally cultured functional hepatocytes generated from human induced pluripotent stem cell-derived hepatic organoids for pharmaceutical research.
    Biomaterials. 2025;318:123148.
    PubMed     Abstract available


  53. YANG X, Mistry M, Chen AD, Chan BP, et al
    Tailoring extracellular matrix niches: Impact of glycosaminoglycan content on multiple differentiation of human mesenchymal stem cells.
    Biomaterials. 2025;318:123130.
    PubMed     Abstract available


  54. TONG X, Ayushman M, Lee HP, Yang F, et al
    Tuning local matrix compliance accelerates mesenchymal stem cell chondrogenesis in 3D sliding hydrogels.
    Biomaterials. 2025;317:123112.
    PubMed     Abstract available


  55. XU C, Li Z, Kang M, Chen Y, et al
    Hydrogel-integrated exosome mimetics derived from osteogenically induced mesenchymal stem cells in spheroid culture enhance bone regeneration.
    Biomaterials. 2025;317:123088.
    PubMed     Abstract available


  56. HOU X, Zhang L, Chen Y, Liu Z, et al
    Photothermal switch by gallic acid-calcium grafts synthesized by coordination chemistry for sequential treatment of bone tumor and regeneration.
    Biomaterials. 2025;312:122724.
    PubMed     Abstract available


  57. CHEUNG HL, Wong YH, Li YY, Yang X, et al
    Microenvironment matters: In vitro 3D bone marrow niches differentially modulate survival, phenotype and drug responses of acute myeloid leukemia (AML) cells.
    Biomaterials. 2025;312:122719.
    PubMed     Abstract available


  58. JIN Y, Wang Y, Yang R, Fang W, et al
    Multilayered hydrogel scaffold construct with native tissue matched elastic modulus: A regenerative microenvironment for urethral scar-free healing.
    Biomaterials. 2025;312:122711.
    PubMed     Abstract available


    December 2024
  59. YAN C, Zhang P, Qin Q, Jiang K, et al
    3D-printed bone regeneration scaffolds modulate bone metabolic homeostasis through vascularization for osteoporotic bone defects.
    Biomaterials. 2024;311:122699.
    PubMed     Abstract available


  60. HUANG N, Chan BP
    A 3D micro-printed single cell micro-niche with asymmetric niche signals - An in vitro model for asymmetric cell division study.
    Biomaterials. 2024;311:122684.
    PubMed     Abstract available


  61. LIU X, Li J, Zhu L, Huang J, et al
    Mechanistic insights into zinc oxide nanoparticles induced embryotoxicity via H3K9me3 modulation.
    Biomaterials. 2024;311:122679.
    PubMed     Abstract available


  62. ZHENG W, Ma L, Luo X, Xu R, et al
    Ultrasound-triggered functional hydrogel promotes multistage bone regeneration.
    Biomaterials. 2024;311:122650.
    PubMed     Abstract available


  63. YI E, Go J, Yun SH, Lee SE, et al
    CEACAM1-engineered MSCs have a broad spectrum of immunomodulatory functions and therapeutic potential via cell-to-cell interaction.
    Biomaterials. 2024;311:122667.
    PubMed     Abstract available


    November 2024
  64. CHEN T, Lau KSK, Singh A, Zhang YX, et al
    Biodegradable stimulating electrodes for resident neural stem cell activation in vivo.
    Biomaterials. 2024;315:122957.
    PubMed     Abstract available


    October 2024
  65. MULERO-RUSSE A, Mora-Boza A, Marquez EN, Ziegelski M, et al
    Synthetic hydrogel substrate for human induced pluripotent stem cell definitive endoderm differentiation.
    Biomaterials. 2024;315:122920.
    PubMed     Abstract available


  66. JIN Y, Zhang J, Chen X, Li F, et al
    3D printing incorporating gold nanozymes with mesenchymal stem cell-derived hepatic spheroids for acute liver failure treatment.
    Biomaterials. 2024;315:122895.
    PubMed     Abstract available


  67. FAN MH, Zhang XZ, Jiang YL, Pi JK, et al
    Exosomes from hypoxic urine-derived stem cells facilitate healing of diabetic wound by targeting SERPINE1 through miR-486-5p.
    Biomaterials. 2024;314:122893.
    PubMed     Abstract available


  68. TANG J, Zhang P, Liu Y, Hou D, et al
    Revolutionizing pressure ulcer regeneration: Unleashing the potential of extracellular matrix-derived temperature-sensitive injectable antioxidant hydrogel for superior stem cell therapy.
    Biomaterials. 2024;314:122880.
    PubMed     Abstract available


    September 2024
  69. PAN Y, Li L, Cao N, Liao J, et al
    Advanced nano delivery system for stem cell therapy for Alzheimer's disease.
    Biomaterials. 2024;314:122852.
    PubMed     Abstract available


  70. MU L, Dong R, Li C, Chen J, et al
    ROS responsive conductive microspheres loaded with salvianolic acid B as adipose derived stem cell carriers for acute myocardial infarction treatment.
    Biomaterials. 2024;314:122849.
    PubMed     Abstract available


  71. HE Q, Liao Y, Zhang H, Sun W, et al
    Gel microspheres enhance the stemness of ADSCs by regulating cell-ECM interaction.
    Biomaterials. 2024;309:122616.
    PubMed     Abstract available


  72. SONG T, Zhao F, Yan L, Liu P, et al
    Structure driven bio-responsive ability of injectable nanocomposite hydrogels for efficient bone regeneration.
    Biomaterials. 2024;309:122601.
    PubMed     Abstract available


    August 2024
  73. XIAO C, Wang X, Li S, Zhang Z, et al
    A cuproptosis-based nanomedicine suppresses triple negative breast cancers by regulating tumor microenvironment and eliminating cancer stem cells.
    Biomaterials. 2024;313:122763.
    PubMed     Abstract available


  74. ZHANG Y, Zhao Y, An C, Guo Y, et al
    Material-driven immunomodulation and ECM remodeling reverse pulmonary fibrosis by local delivery of stem cell-laden microcapsules.
    Biomaterials. 2024;313:122757.
    PubMed     Abstract available


    July 2024
  75. NA J, Tai C, Wang Z, Yang Z, et al
    Stiff extracellular matrix drives the differentiation of mesenchymal stem cells toward osteogenesis by the multiscale 3D genome reorganization.
    Biomaterials. 2024;312:122715.
    PubMed     Abstract available


  76. WU C, Huang Z, Chen J, Li N, et al
    Efficiently directing differentiation and homing of mesenchymal stem cells to boost cartilage repair in osteoarthritis via a nanoparticle and peptide dual-engineering strategy.
    Biomaterials. 2024;312:122720.
    PubMed     Abstract available


  77. RANDHAWA A, Ganguly K, Dutta SD, Patil TV, et al
    Transcriptomic profiling of human mesenchymal stem cells using a pulsed electromagnetic-wave motion bioreactor system for enhanced osteogenic commitment and therapeutic potentials.
    Biomaterials. 2024;312:122713.
    PubMed     Abstract available


  78. YANG Y, Peng Y, Du Y, Lin M, et al
    Hierarchical self-recognition and response in CSC and non-CSC micro-niches for cancer therapy.
    Biomaterials. 2024;308:122581.
    PubMed     Abstract available


  79. JIANG W, Zhan Y, Zhang Y, Sun D, et al
    Synergistic large segmental bone repair by 3D printed bionic scaffolds and engineered ADSC nanovesicles: Towards an optimized regenerative microenvironment.
    Biomaterials. 2024;308:122566.
    PubMed     Abstract available


  80. YANG Y, Zhang J, Wu S, Deng Y, et al
    Exosome/antimicrobial peptide laden hydrogel wound dressings promote scarless wound healing through miR-21-5p-mediated multiple functions.
    Biomaterials. 2024;308:122558.
    PubMed     Abstract available


  81. DONGES L, Damle A, Mainardi A, Bock T, et al
    Engineered human osteoarthritic cartilage organoids.
    Biomaterials. 2024;308:122549.
    PubMed     Abstract available


  82. HOLLAND EN, Fernandez-Yague MA, Zhou DW, O'Neill EB, et al
    FAK, vinculin, and talin control mechanosensitive YAP nuclear localization.
    Biomaterials. 2024;308:122542.
    PubMed     Abstract available


    May 2024
  83. WANG L, Koui Y, Kanegae K, Kido T, et al
    Establishment of human induced pluripotent stem cell-derived hepatobiliary organoid with bile duct for pharmaceutical research use.
    Biomaterials. 2024;310:122621.
    PubMed     Abstract available


    April 2024
  84. PALOMARES CABEZA V, Fahy N, Kiernan CH, Lolli A, et al
    Bone formation by human paediatric marrow stromal cells in a functional allogeneic immune system.
    Biomaterials. 2024;306:122471.
    PubMed     Abstract available


  85. KERSEY AL, Cheng DY, Deo KA, Dubell CR, et al
    Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs.
    Biomaterials. 2024;306:122473.
    PubMed     Abstract available


    March 2024
  86. LIANG W, Han M, Li G, Dang W, et al
    Perfusable adipose decellularized extracellular matrix biological scaffold co-recellularized with adipose-derived stem cells and L6 promotes functional skeletal muscle regeneration following volumetric muscle loss.
    Biomaterials. 2024;307:122529.
    PubMed     Abstract available


  87. AN C, Shao F, Long C, Zhang Y, et al
    Local delivery of stem cell spheroids with protein/polyphenol self-assembling armor to improve myocardial infarction treatment via immunoprotection and immunoregulation.
    Biomaterials. 2024;307:122526.
    PubMed     Abstract available


    February 2024
  88. HUANG D, Yang X, Peng Z, Yin H, et al
    Multichannel-optical imaging for in vivo evaluating the safety and therapeutic efficacy of stem cells in tumor model in terms of cell tropism, proliferation and NF-kappaB activity.
    Biomaterials. 2024;307:122510.
    PubMed     Abstract available


  89. KWAK S, Song CL, Lee J, Kim S, et al
    Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration.
    Biomaterials. 2024;307:122522.
    PubMed     Abstract available


    December 2023
  90. SALAS-SILVA S, Kim Y, Kim TH, Kim M, et al
    Human chemically-derived hepatic progenitors (hCdHs) as a source of liver organoid generation: Application in regenerative medicine, disease modeling, and toxicology testing.
    Biomaterials. 2023;303:122360.
    PubMed     Abstract available


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