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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 49 articles:
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Single Articles


    June 2025
  1. SHARMA B, Aswin K, Jain T, Nasreen A, et al
    Mgat4b-mediated selective N-glycosylation regulates melanocyte development and melanoma progression.
    Proc Natl Acad Sci U S A. 2025;122:e2423831122.
    PubMed     Abstract available


    May 2025
  2. FERRERO G, Cardamone MD, Luca F, Bourk E, et al
    Nonproteolytic ubiquitination regulates chromatin occupancy by the NCoR/SMRT/HDAC3 corepressor complex in MCF-7 breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2502805122.
    PubMed     Abstract available


    April 2025
  3. FOFFI E, Rugolo F, Ramamurthy N, Haight J, et al
    B cell-derived acetylcholine mitigates skin inflammation in mice through alpha9 nicotinic acetylcholine receptor-mediated signaling.
    Proc Natl Acad Sci U S A. 2025;122:e2501960122.
    PubMed     Abstract available


  4. CHEN YF, Zhang QH, Zhang ZW, Zhou YJ, et al
    SNX10 deficiency impairs sensitivity to anti-HER2 antibody-drug conjugates via altering HER2 trafficking in HER2-positive breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2417586122.
    PubMed     Abstract available


  5. ZHAO X, Zhao Y, Li Z, Liu H, et al
    Proximity-activated DNA scanning encoded sequencing for massive access to membrane proteins nanoscale organization.
    Proc Natl Acad Sci U S A. 2025;122:e2425000122.
    PubMed     Abstract available


    March 2025
  6. NAZERAI L, Tsiavou C, Vardouli L, Schmiegelow K, et al
    Thiopurine therapy enhances immune checkpoint inhibitor efficacy in low-mutational burden melanoma: A promising anticancer approach.
    Proc Natl Acad Sci U S A. 2025;122:e2423246122.
    PubMed     Abstract available


  7. STAROSTECKA M, Jeong H, Hasenfeld P, Benito-Garagorri E, et al
    Structural variant and nucleosome occupancy dynamics postchemotherapy in a HER2+ breast cancer organoid model.
    Proc Natl Acad Sci U S A. 2025;122:e2415475122.
    PubMed     Abstract available


    February 2025
  8. YI J, Du J, Chen X, Nie RC, et al
    A circRNA-mRNA pairing mechanism regulates tumor growth and endocrine therapy resistance in ER-positive breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2420383122.
    PubMed     Abstract available


  9. LEI L, Song Y, Yang L, Wang Y, et al
    Triethylamine-mediated protonation-deprotonation unlocks dual-drug self assembly to suppress breast cancer progression and metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2416796122.
    PubMed     Abstract available


    January 2025
  10. KRAKOWIAK PA, Flores ME, Cuddy SR, Whitford AL, et al
    Co-option of mitochondrial nucleic acid-sensing pathways by HSV-1 UL12.5 for reactivation from latent infection.
    Proc Natl Acad Sci U S A. 2025;122:e2413965122.
    PubMed     Abstract available


  11. CORRALES RM, Vincent J, Crobu L, Neish R, et al
    Tubulin detyrosination shapes Leishmania cytoskeletal architecture and virulence.
    Proc Natl Acad Sci U S A. 2025;122:e2415296122.
    PubMed     Abstract available


  12. QIN G, Shao X, Liu X, Xu J, et al
    A signaling molecule from intratumor bacteria promotes trastuzumab resistance in breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2421710122.
    PubMed     Abstract available


  13. ZHENG M, Wang S, Tang K, Kong R, et al
    The CYLD-PARP1 feedback loop regulates DNA damage repair and chemosensitivity in breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2413890121.
    PubMed     Abstract available


    December 2024
  14. GONZALEZ-FERNANDEZ M, Perry C, Gerhards NM, Francica P, et al
    Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by Huntingtin and BAP1.
    Proc Natl Acad Sci U S A. 2024;121:e2402849121.
    PubMed     Abstract available


  15. CATTA-PRETA CMC, Ghosh K, Sacks DL, Ferreira TR, et al
    Single-cell atlas of Leishmania development in sandflies reveals the heterogeneity of transmitted parasites and their role in infection.
    Proc Natl Acad Sci U S A. 2024;121:e2406776121.
    PubMed     Abstract available


  16. SINHA A, Saini KK, Chandramouli A, Tripathi K, et al
    ACSL4-mediated H3K9 and H3K27 hyperacetylation upregulates SNAIL to drive TNBC metastasis.
    Proc Natl Acad Sci U S A. 2024;121:e2408049121.
    PubMed     Abstract available


  17. MATSUZAKI T, Fujii M, Noro H, Togo S, et al
    Simultaneous visualization of membrane fluidity and morphology defines adhesion signatures of cancer cells.
    Proc Natl Acad Sci U S A. 2024;121:e2412914121.
    PubMed     Abstract available


  18. ROUBILLE S, Escure T, Juillard F, Corpet A, et al
    The HUSH epigenetic repressor complex silences PML nuclear body-associated HSV-1 quiescent genomes.
    Proc Natl Acad Sci U S A. 2024;121:e2412258121.
    PubMed     Abstract available


    November 2024
  19. KASHYAP MP, Mishra B, Sinha R, Jin L, et al
    CD2 expressing innate lymphoid and T cells are critical effectors of immunopathogenesis in hidradenitis suppurativa.
    Proc Natl Acad Sci U S A. 2024;121:e2409274121.
    PubMed     Abstract available


  20. LADAK RJ, Choi JH, Luo J, Chen OJ, et al
    The 4EHP-mediated translational repression of cGAS impedes the host immune response against DNA viruses.
    Proc Natl Acad Sci U S A. 2024;121:e2413018121.
    PubMed     Abstract available


  21. DING X, Liang J, Sharko AC, Hilimire TA, et al
    Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors.
    Proc Natl Acad Sci U S A. 2024;121:e2414501121.
    PubMed     Abstract available


  22. ARULRAJ T, Wang H, Deshpande A, Varadhan R, et al
    Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade.
    Proc Natl Acad Sci U S A. 2024;121:e2410911121.
    PubMed     Abstract available


    October 2024
  23. VALCIKOVA B, Vadovicova N, Smolkova K, Zacpalova M, et al
    eIF4F controls ERK MAPK signaling in melanomas with BRAF and NRAS mutations.
    Proc Natl Acad Sci U S A. 2024;121:e2321305121.
    PubMed     Abstract available


  24. LI C, Kaur A, Pavlidaki A, Spenle C, et al
    Targeting the MAtrix REgulating MOtif abolishes several hallmarks of cancer, triggering antitumor immunity.
    Proc Natl Acad Sci U S A. 2024;121:e2404485121.
    PubMed     Abstract available


  25. BALDASSARRI I, Tavakol DN, Graney PL, Chramiec AG, et al
    An engineered model of metastatic colonization of human bone marrow reveals breast cancer cell remodeling of the hematopoietic niche.
    Proc Natl Acad Sci U S A. 2024;121:e2405257121.
    PubMed     Abstract available


  26. ASEMOTA S, Effah W, Holt J, Johnson D, et al
    A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity.
    Proc Natl Acad Sci U S A. 2024;121:e2406837121.
    PubMed     Abstract available


    September 2024
  27. FENG X, Yang C, Huang Y, Su D, et al
    In vivo CRISPR screens identify Mga as an immunotherapy target in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2406325121.
    PubMed     Abstract available


  28. LOY CJ, Servellita V, Sotomayor-Gonzalez A, Bliss A, et al
    Plasma cell-free RNA signatures of inflammatory syndromes in children.
    Proc Natl Acad Sci U S A. 2024;121:e2403897121.
    PubMed     Abstract available


    August 2024
  29. MUKOHARA F, Iwata K, Ishino T, Inozume T, et al
    Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity.
    Proc Natl Acad Sci U S A. 2024;121:e2320189121.
    PubMed     Abstract available


  30. PIRONON N, Bourrat E, Prost C, Chen M, et al
    Splice modulation strategy applied to deep intronic variants in COL7A1 causing recessive dystrophic epidermolysis bullosa.
    Proc Natl Acad Sci U S A. 2024;121:e2401781121.
    PubMed     Abstract available


  31. CHIANG HC, Qi L, Mitra P, Huang Y, et al
    R-loop functions in Brca1-associated mammary tumorigenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2403600121.
    PubMed     Abstract available


    July 2024
  32. SHAH OS, Nasrazadani A, Foldi J, Atkinson JM, et al
    Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.
    Proc Natl Acad Sci U S A. 2024;121:e2322068121.
    PubMed     Abstract available


  33. ZIN I, China A, Khan K, Nag JK, et al
    AKT-dependent nuclear localization of EPRS1 activates PARP1 in breast cancer cells.
    Proc Natl Acad Sci U S A. 2024;121:e2303642121.
    PubMed     Abstract available


  34. ZHOU Q, Yu H, Chen Y, Ren J, et al
    The CRL3(KCTD10) ubiquitin ligase-USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11.
    Proc Natl Acad Sci U S A. 2024;121:e2320655121.
    PubMed     Abstract available


    June 2024
  35. DI LEO L, Pagliuca C, Kishk A, Rizza S, et al
    AMBRA1 levels predict resistance to MAPK inhibitors in melanoma.
    Proc Natl Acad Sci U S A. 2024;121:e2400566121.
    PubMed     Abstract available


  36. RUAN ML, Ni WX, Chu JCH, Lam TL, et al
    Iridium(III) carbene complexes as potent girdin inhibitors against metastatic cancers.
    Proc Natl Acad Sci U S A. 2024;121:e2316615121.
    PubMed     Abstract available


  37. NEBO ID, Frew JW, Gudjonsson JE, Petukhova L, et al
    Tissue comparability and bias in hidradenitis suppurativa transcriptomic studies.
    Proc Natl Acad Sci U S A. 2024;121:e2404503121.
    PubMed    


  38. JIN L, Kashyap MP, Haque ST, Li C, et al
    Reply to Nebo et al.: Pathogenesis of advanced hidradenitis suppurativa: Are there differences based on anatomical location, gender, and race?
    Proc Natl Acad Sci U S A. 2024;121:e2405298121.
    PubMed    


    May 2024

  39. Correction for Ichimura et al., Autoimmunity against melanoma differentiation-associated gene 5 induces interstitial lung disease mimicking dermatomyositis in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2408646121.
    PubMed    


  40. CHEN J, Liu X, Zou Y, Gong J, et al
    A high-fat diet promotes cancer progression by inducing gut microbiota-mediated leucine production and PMN-MDSC differentiation.
    Proc Natl Acad Sci U S A. 2024;121:e2306776121.
    PubMed     Abstract available


  41. ASHOKAN A, Sarkar S, Kamran MZ, Surnar B, et al
    Simultaneous targeting of peripheral and brain tumors with a therapeutic nanoparticle to disrupt metabolic adaptability at both sites.
    Proc Natl Acad Sci U S A. 2024;121:e2318119121.
    PubMed     Abstract available


  42. GOYETTE MA, Stevens LE, DePinho CR, Seehawer M, et al
    Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
    Proc Natl Acad Sci U S A. 2024;121:e2322688121.
    PubMed     Abstract available


    April 2024
  43. MONDAL DK, Xie C, Pascal GJ, Buraschi S, et al
    Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer progression.
    Proc Natl Acad Sci U S A. 2024;121:e2317760121.
    PubMed     Abstract available


  44. ICHIMURA Y, Konishi R, Shobo M, Tanaka R, et al
    Autoimmunity against melanoma differentiation-associated gene 5 induces interstitial lung disease mimicking dermatomyositis in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2313070121.
    PubMed     Abstract available


  45. PIRES L, Khattak S, Pratavieira S, Calcada C, et al
    Femtosecond pulsed laser photodynamic therapy activates melanin and eradicates malignant melanoma.
    Proc Natl Acad Sci U S A. 2024;121:e2316303121.
    PubMed     Abstract available


    March 2024
  46. WANG D, Tang M, Zhang P, Yang K, et al
    Activation of ERbeta hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2306814121.
    PubMed     Abstract available


  47. GOUPIL E, Lacroix L, Briere J, Guga S, et al
    OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis.
    Proc Natl Acad Sci U S A. 2024;121:e2308570121.
    PubMed     Abstract available


  48. TAYLOR-PHILLIPS S, Jenkinson D, Stinton C, Kunar MA, et al
    Fatigue and vigilance in medical experts detecting breast cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2309576121.
    PubMed     Abstract available


  49. LAMIA KA
    Telling time in tumor samples reveals diversity of clock disruption.
    Proc Natl Acad Sci U S A. 2024;121:e2401496121.
    PubMed    


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