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COVID-19: Daily Top 10 Papers


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Articles published in Proc Natl Acad Sci U S A

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    June 2021
  1. ZHAO J, Jaffe A, Li H, Lindenbaum O, et al
    Detection of differentially abundant cell subpopulations in scRNA-seq data.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  2. HU JK, Suh HW, Qureshi M, Lewis JM, et al
    Nonsurgical treatment of skin cancer with local delivery of bioadhesive nanoparticles.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  3. JAYABALAN AK, Adivarahan S, Koppula A, Abraham R, et al
    Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  4. JIMENEZ-SANCHEZ J, Bosque JJ, Jimenez Londono GA, Molina-Garcia D, et al
    Evolutionary dynamics at the tumor edge reveal metabolic imaging biomarkers.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  5. WIJSHAKE T, Zou Z, Chen B, Zhong L, et al
    Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  6. MILLER HL, Andhey PS, Swiecki MK, Rosa BA, et al
    Altered ratio of dendritic cell subsets in skin-draining lymph nodes promotes Th2-driven contact hypersensitivity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  7. CHANG PH, Chen MC, Tsai YP, Tan GYT, et al
    Interplay between desmoglein2 and hypoxia controls metastasis in breast cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  8. DAMAGHI M, West J, Robertson-Tessi M, Xu L, et al
    The harsh microenvironment in early breast cancer selects for a Warburg phenotype.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  9. COLLINS KH, Lenz KL, Pollitt EN, Ferguson D, et al
    Adipose tissue is a critical regulator of osteoarthritis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  10. SENDA N, Yanai H, Hibino S, Li L, et al
    HMGB1-mediated chromatin remodeling attenuates Il24 gene expression for the protection from allergic contact dermatitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  11. TOWELL AM, Feuillie C, Vitry P, Da Costa TM, et al
    Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  12. SURESH BM, Li W, Zhang P, Wang KW, et al
    A general fragment-based approach to identify and optimize bioactive ligands targeting RNA.
    Proc Natl Acad Sci U S A. 2020;117:33197-33203.
    PubMed     Abstract available


  13. GAO Y, Chen X, He Q, Gimple RC, et al
    Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin.
    Proc Natl Acad Sci U S A. 2020;117:33295-33304.
    PubMed     Abstract available


  14. NOGALSKI MT, Shenk T
    HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and promotes tumor cell proliferation and movement.
    Proc Natl Acad Sci U S A. 2020;117:31891-31901.
    PubMed     Abstract available


  15. FORTINO V, Wisgrill L, Werner P, Suomela S, et al
    Machine-learning-driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2009192117.
    PubMed     Abstract available


  16. KIM O, Park EY, Kwon SY, Shin S, et al
    Targeting progesterone signaling prevents metastatic ovarian cancer.
    Proc Natl Acad Sci U S A. 2020 Dec 1. pii: 2013595117.
    PubMed     Abstract available


    November 2020
  17. SOUFARI H, Waltz F, Parrot C, Durrieu-Gaillard S, et al
    Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
    Proc Natl Acad Sci U S A. 2020;117:29851-29861.
    PubMed     Abstract available


  18. BARONE M, Muller M, Chiha S, Ren J, et al
    Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
    Proc Natl Acad Sci U S A. 2020 Nov 12. pii: 2007213117.
    PubMed     Abstract available


  19. WEAVER VM, Bissell MJ
    Zena Werb (1945-2020): Mourning the loss of a tissue microenvironment icon.
    Proc Natl Acad Sci U S A. 2020;117:27759-27760.
    PubMed    


  20. OUYANG J, Ji X, Zhang X, Feng C, et al
    In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment.
    Proc Natl Acad Sci U S A. 2020 Nov 2. pii: 2016268117.
    PubMed     Abstract available


    October 2020
  21. XUAN B, Ghosh D, Jiang J, Shao R, et al
    Vimentin filaments drive migratory persistence in polyploidal cancer cells.
    Proc Natl Acad Sci U S A. 2020;117:26756-26765.
    PubMed     Abstract available


  22. YANG PB, Hou PP, Liu FY, Hong WB, et al
    Blocking PPARgamma interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.
    Proc Natl Acad Sci U S A. 2020 Oct 21. pii: 2002997117.
    PubMed     Abstract available


  23. PRATT SJP, Lee RM, Chang KT, Hernandez-Ochoa EO, et al
    Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca(2+) signals that are inhibited by oncogenic KRas.
    Proc Natl Acad Sci U S A. 2020;117:26008-26019.
    PubMed     Abstract available


  24. LOEILLET S, Herzog M, Puddu F, Legoix P, et al
    Trajectory and uniqueness of mutational signatures in yeast mutators.
    Proc Natl Acad Sci U S A. 2020;117:24947-24956.
    PubMed     Abstract available


    September 2020
  25. SPANGLE JM, Von T, Pavlick DC, Khotimsky A, et al
    PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-alpha inhibition.
    Proc Natl Acad Sci U S A. 2020;117:24427-24433.
    PubMed     Abstract available


  26. CHAPMAN LAC, Spencer SEF, Pollington TM, Jewell CP, et al
    Inferring transmission trees to guide targeting of interventions against visceral leishmaniasis and post-kala-azar dermal leishmaniasis.
    Proc Natl Acad Sci U S A. 2020 Sep 24. pii: 2002731117.
    PubMed     Abstract available


  27. CHEN IX, Newcomer K, Pauken KE, Juneja VR, et al
    A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade.
    Proc Natl Acad Sci U S A. 2020;117:23684-23694.
    PubMed     Abstract available


  28. VAN DEN BROECK F, Savill NJ, Imamura H, Sanders M, et al
    Ecological divergence and hybridization of Neotropical Leishmania parasites.
    Proc Natl Acad Sci U S A. 2020 Sep 21. pii: 1920136117.
    PubMed     Abstract available


    August 2020
  29. KHATIB A, Solaimuthu B, Ben Yosef M, Abu Rmaileh A, et al
    The glutathione peroxidase 8 (GPX8)/IL-6/STAT3 axis is essential in maintaining an aggressive breast cancer phenotype.
    Proc Natl Acad Sci U S A. 2020 Aug 18. pii: 2010275117.
    PubMed     Abstract available


    July 2020
  30. MCLAUGHLIN LJ, Stojanovic L, Kogan AA, Rutherford JL, et al
    Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency.
    Proc Natl Acad Sci U S A. 2020;117:17785-17795.
    PubMed     Abstract available


  31. CALLMANN CE, Cole LE, Kusmierz CD, Huang Z, et al
    Tumor cell lysate-loaded immunostimulatory spherical nucleic acids as therapeutics for triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2020 Jul 15. pii: 2005794117.
    PubMed     Abstract available


  32. HURABIELLE C, Link VM, Bouladoux N, Han SJ, et al
    Immunity to commensal skin fungi promotes psoriasiform skin inflammation.
    Proc Natl Acad Sci U S A. 2020;117:16465-16474.
    PubMed     Abstract available


  33. ZERVANTONAKIS IK, Poskus MD, Scott AL, Selfors LM, et al
    Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways.
    Proc Natl Acad Sci U S A. 2020;117:16500-16508.
    PubMed     Abstract available


    June 2020
  34. GRAVES JD, Lee YJ, Liu K, Li G, et al
    E2F1 sumoylation as a protective cellular mechanism in oxidative stress response.
    Proc Natl Acad Sci U S A. 2020;117:14958-14969.
    PubMed     Abstract available


  35. TSUTAKAWA SE, Sarker AH, Ng C, Arvai AS, et al
    Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations.
    Proc Natl Acad Sci U S A. 2020;117:14127-14138.
    PubMed     Abstract available


  36. MANTHIRAM K, Preite S, Dedeoglu F, Demir S, et al
    Common genetic susceptibility loci link PFAPA syndrome, Behcet's disease, and recurrent aphthous stomatitis.
    Proc Natl Acad Sci U S A. 2020;117:14405-14411.
    PubMed     Abstract available


  37. SAHA LK, Wakasugi M, Akter S, Prasad R, et al
    Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells.
    Proc Natl Acad Sci U S A. 2020;117:14412-14420.
    PubMed     Abstract available


  38. LIU W, Kim GB, Krump NA, Zhou Y, et al
    Selective reactivation of STING signaling to target Merkel cell carcinoma.
    Proc Natl Acad Sci U S A. 2020;117:13730-13739.
    PubMed     Abstract available


  39. ZHU N, Zhang J, Du Y, Qin X, et al
    Loss of ZIP facilitates JAK2-STAT3 activation in tamoxifen-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2020 Jun 12. pii: 1910278117.
    PubMed     Abstract available


    May 2020
  40. ZHANG Z, Gallagher T, Scherer PE, Beutler B, et al
    Tissue-specific disruption of Kbtbd2 uncovers adipocyte-intrinsic and -extrinsic features of the teeny lipodystrophy syndrome.
    Proc Natl Acad Sci U S A. 2020;117:11829-11835.
    PubMed     Abstract available


  41. PYO A, Kim DY, Kim H, Lim D, et al
    Ultrasensitive detection of malignant melanoma using PET molecular imaging probes.
    Proc Natl Acad Sci U S A. 2020 May 21. pii: 1922313117.
    PubMed     Abstract available


    April 2020
  42. LEE S, Hu Y, Loo SK, Tan Y, et al
    Landscape analysis of adjacent gene rearrangements reveals BCL2L14-ETV6 gene fusions in more aggressive triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2020 Apr 22. pii: 1921333117.
    PubMed     Abstract available


  43. CARVAJAL-GARCIA J, Cho JE, Carvajal-Garcia P, Feng W, et al
    Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
    Proc Natl Acad Sci U S A. 2020;117:8476-8485.
    PubMed     Abstract available


  44. LEUNG KK, Wilson GM, Kirkemo LL, Riley NM, et al
    Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.
    Proc Natl Acad Sci U S A. 2020;117:7764-7775.
    PubMed     Abstract available


  45. KUMAR S, Singh SK, Viswakarma N, Sondarva G, et al
    Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.
    Proc Natl Acad Sci U S A. 2020;117:7961-7970.
    PubMed     Abstract available


    March 2020
  46. NICOLET BP, Guislain A, van Alphen FPJ, Gomez-Eerland R, et al
    CD29 identifies IFN-gamma-producing human CD8(+) T cells with an increased cytotoxic potential.
    Proc Natl Acad Sci U S A. 2020;117:6686-6696.
    PubMed     Abstract available


  47. SHARMA S, Zhang T, Michowski W, Rebecca VW, et al
    Targeting the cyclin-dependent kinase 5 in metastatic melanoma.
    Proc Natl Acad Sci U S A. 2020 Mar 19. pii: 1912617117.
    PubMed     Abstract available


  48. YI Y, Chen D, Ao J, Zhang W, et al
    Transcriptional suppression of AMPKalpha1 promotes breast cancer metastasis upon oncogene activation.
    Proc Natl Acad Sci U S A. 2020 Mar 19. pii: 1914786117.
    PubMed     Abstract available


  49. NA TY, Schecterson L, Mendonsa AM, Gumbiner BM, et al
    The functional activity of E-cadherin controls tumor cell metastasis at multiple steps.
    Proc Natl Acad Sci U S A. 2020;117:5931-5937.
    PubMed     Abstract available


  50. PHILLIPS JW, Pan Y, Tsai BL, Xie Z, et al
    Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers.
    Proc Natl Acad Sci U S A. 2020;117:5269-5279.
    PubMed     Abstract available


  51. CHOI JH, Han J, Theodoropoulos PC, Zhong X, et al
    Essential requirement for nicastrin in marginal zone and B-1 B cell development.
    Proc Natl Acad Sci U S A. 2020;117:4894-4901.
    PubMed     Abstract available


  52. KESAVAN R, Fromel T, Zukunft S, Laban H, et al
    Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer.
    Proc Natl Acad Sci U S A. 2020 Mar 2. pii: 1921381117.
    PubMed     Abstract available


    February 2020
  53. SCHNELL M, Mittal S, Falahkheirkhah K, Mittal A, et al
    All-digital histopathology by infrared-optical hybrid microscopy.
    Proc Natl Acad Sci U S A. 2020;117:3388-3396.
    PubMed     Abstract available


  54. BRANDT AC, McNally L, Lorimer EL, Unger B, et al
    Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy.
    Proc Natl Acad Sci U S A. 2020;117:3627-3636.
    PubMed     Abstract available


  55. XIONG G, Chen J, Zhang G, Wang S, et al
    Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction.
    Proc Natl Acad Sci U S A. 2020;117:3748-3758.
    PubMed     Abstract available


  56. YAMAMOTO H, Hattori M, Chamulitrat W, Ohno Y, et al
    Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid omega-O-acylceramide.
    Proc Natl Acad Sci U S A. 2020;117:2914-2922.
    PubMed     Abstract available


  57. COSTALES MG, Aikawa H, Li Y, Childs-Disney JL, et al
    Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer.
    Proc Natl Acad Sci U S A. 2020;117:2406-2411.
    PubMed     Abstract available


    January 2020
  58. PUGACHEVA EM, Kubo N, Loukinov D, Tajmul M, et al
    CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention.
    Proc Natl Acad Sci U S A. 2020;117:2020-2031.
    PubMed     Abstract available


  59. GALLAGHER FA, Woitek R, McLean MA, Gill AB, et al
    Imaging breast cancer using hyperpolarized carbon-13 MRI.
    Proc Natl Acad Sci U S A. 2020 Jan 21. pii: 1913841117.
    PubMed     Abstract available


  60. NEWMAN JH, Chesson CB, Herzog NL, Bommareddy PK, et al
    Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer.
    Proc Natl Acad Sci U S A. 2020;117:1119-1128.
    PubMed     Abstract available


  61. BLOCKHUYS S, Zhang X, Wittung-Stafshede P
    Single-cell tracking demonstrates copper chaperone Atox1 to be required for breast cancer cell migration.
    Proc Natl Acad Sci U S A. 2020 Jan 13. pii: 1910722117.
    PubMed     Abstract available


  62. WINKLER I, Bitter C, Winkler S, Weichenhan D, et al
    Identification of Ppargamma-modulated miRNA hubs that target the fibrotic tumor microenvironment.
    Proc Natl Acad Sci U S A. 2020;117:454-463.
    PubMed     Abstract available


  63. LIN CW, Xie J, Zhang D, Han KH, et al
    Immunity against cancer cells may promote their proliferation and metastasis.
    Proc Natl Acad Sci U S A. 2020;117:426-431.
    PubMed     Abstract available


    December 2019
  64. GOURH P, Safran SA, Alexander T, Boyden SE, et al
    HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry.
    Proc Natl Acad Sci U S A. 2019 Dec 23. pii: 1906593116.
    PubMed     Abstract available


  65. COHEN EM, Avital N, Shamay M, Kobiler O, et al
    Abortive herpes simplex virus infection of nonneuronal cells results in quiescent viral genomes that can reactivate.
    Proc Natl Acad Sci U S A. 2019 Dec 23. pii: 1910537117.
    PubMed     Abstract available


  66. LEE CJ, An HJ, Kim SM, Yoo SM, et al
    FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation.
    Proc Natl Acad Sci U S A. 2019 Dec 16. pii: 1909879116.
    PubMed     Abstract available


  67. BANERJEE S, Wei T, Wang J, Lee JJ, et al
    Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.
    Proc Natl Acad Sci U S A. 2019;116:24881-24891.
    PubMed     Abstract available


    November 2019
  68. HJELMELAND AB, Patel RP
    SOD2 acetylation and deacetylation: Another tale of Jekyll and Hyde in cancer.
    Proc Natl Acad Sci U S A. 2019;116:23376-23378.
    PubMed    


  69. YOU S, Barkalifa R, Chaney EJ, Tu H, et al
    Label-free visualization and characterization of extracellular vesicles in breast cancer.
    Proc Natl Acad Sci U S A. 2019 Nov 15. pii: 1909243116.
    PubMed     Abstract available


  70. PREMI S, Han L, Mehta S, Knight J, et al
    Genomic sites hypersensitive to ultraviolet radiation.
    Proc Natl Acad Sci U S A. 2019 Nov 13. pii: 1907860116.
    PubMed     Abstract available


  71. RODRIGUES-FERREIRA S, Nehlig A, Moindjie H, Monchecourt C, et al
    Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy.
    Proc Natl Acad Sci U S A. 2019 Nov 4. pii: 1910824116.
    PubMed     Abstract available


    October 2019
  72. HE C, Danes JM, Hart PC, Zhu Y, et al
    SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.
    Proc Natl Acad Sci U S A. 2019 Oct 7. pii: 1902308116.
    PubMed     Abstract available


    September 2019
  73. GUO P, Yang J, Huang J, Auguste DT, et al
    Therapeutic genome editing of triple-negative breast tumors using a noncationic and deformable nanolipogel.
    Proc Natl Acad Sci U S A. 2019;116:18295-18303.
    PubMed     Abstract available


    August 2019
  74. SOARES E, Xu Q, Li Q, Qu J, et al
    Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome.
    Proc Natl Acad Sci U S A. 2019;116:17361-17370.
    PubMed     Abstract available


    June 2019
  75. MORGAN MT, Bourassa D, Harankhedkar S, McCallum AM, et al
    Ratiometric two-photon microscopy reveals attomolar copper buffering in normal and Menkes mutant cells.
    Proc Natl Acad Sci U S A. 2019;116:12167-12172.
    PubMed     Abstract available


  76. DU EJ, Ahn TJ, Sung H, Jo H, et al
    Analysis of phototoxin taste closely correlates nucleophilicity to type 1 phototoxicity.
    Proc Natl Acad Sci U S A. 2019;116:12013-12018.
    PubMed     Abstract available


  77. CHI D, Singhal H, Li L, Xiao T, et al
    Estrogen receptor signaling is reprogrammed during breast tumorigenesis.
    Proc Natl Acad Sci U S A. 2019;116:11437-11443.
    PubMed     Abstract available


  78. FLORIAN S, Iwamoto Y, Coughlin M, Weissleder R, et al
    A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor.
    Proc Natl Acad Sci U S A. 2019;116:11444-11453.
    PubMed     Abstract available


    May 2019
  79. BAI J, Wu K, Cao MH, Yang Y, et al
    SCF(FBXO22) targets HDM2 for degradation and modulates breast cancer cell invasion and metastasis.
    Proc Natl Acad Sci U S A. 2019 May 28. pii: 1820990116.
    PubMed     Abstract available


    April 2019
  80. VERMA S, Yeddula N, Soda Y, Zhu Q, et al
    BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling.
    Proc Natl Acad Sci U S A. 2019;116:7363-7370.
    PubMed     Abstract available


  81. SHANBHAG V, Jasmer-McDonald K, Zhu S, Martin AL, et al
    ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis.
    Proc Natl Acad Sci U S A. 2019;116:6836-6841.
    PubMed     Abstract available


    March 2019
  82. CROW M, Lim N, Ballouz S, Pavlidis P, et al
    Predictability of human differential gene expression.
    Proc Natl Acad Sci U S A. 2019;116:6491-6500.
    PubMed     Abstract available


  83. KROGER C, Afeyan A, Mraz J, Eaton EN, et al
    Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells.
    Proc Natl Acad Sci U S A. 2019 Mar 25. pii: 1812876116.
    PubMed     Abstract available


  84. ZHENG X, Narayanan S, Sunkari VG, Eliasson S, et al
    Triggering of a Dll4-Notch1 loop impairs wound healing in diabetes.
    Proc Natl Acad Sci U S A. 2019 Mar 18. pii: 1900351116.
    PubMed     Abstract available


    February 2019
  85. CHUANG PK, Hsiao M, Hsu TL, Chang CF, et al
    Signaling pathway of globo-series glycosphingolipids and beta1,3-galactosyltransferase V (beta3GalT5) in breast cancer.
    Proc Natl Acad Sci U S A. 2019;116:3518-3523.
    PubMed     Abstract available


  86. TSOU PS, Campbell P, Amin MA, Coit P, et al
    Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.
    Proc Natl Acad Sci U S A. 2019;116:3695-3702.
    PubMed     Abstract available


  87. ONDECK MG, Kumar A, Placone JK, Plunkett CM, et al
    Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling.
    Proc Natl Acad Sci U S A. 2019;116:3502-3507.
    PubMed     Abstract available


  88. JIA D, Lu M, Jung KH, Park JH, et al
    Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways.
    Proc Natl Acad Sci U S A. 2019;116:3909-3918.
    PubMed     Abstract available


  89. SLEDGE GW
    Targeting CXCR4-induced desmoplasia to improve checkpoint inhibition in breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 22. pii: 1900368116.
    PubMed    


  90. VOUTOURI C, Kirkpatrick ND, Chung E, Mpekris F, et al
    Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies.
    Proc Natl Acad Sci U S A. 2019;116:2662-2671.
    PubMed     Abstract available


  91. AMERI AH, Moradi Tuchayi S, Zaalberg A, Park JH, et al
    IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation.
    Proc Natl Acad Sci U S A. 2019;116:2646-2651.
    PubMed     Abstract available


  92. LI X, Gruosso T, Zuo D, Omeroglu A, et al
    Infiltration of CD8(+) T cells into tumor cell clusters in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1817652116.
    PubMed     Abstract available


  93. KUBLI SP, Bassi C, Roux C, Wakeham A, et al
    AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1815126116.
    PubMed     Abstract available


  94. BLASCO-BENITO S, Moreno E, Seijo-Vila M, Tundidor I, et al
    Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1815034116.
    PubMed     Abstract available


    January 2019
  95. KOBOLD S
    Innate and adaptive immunity combined for cancer treatment.
    Proc Natl Acad Sci U S A. 2019;116:1087-1088.
    PubMed    


  96. HONG WD, Benayoud F, Nixon GL, Ford L, et al
    AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
    Proc Natl Acad Sci U S A. 2019;116:1414-1419.
    PubMed     Abstract available


  97. ZHANG S, Zhang H, Ghia EM, Huang J, et al
    Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.
    Proc Natl Acad Sci U S A. 2019 Jan 8. pii: 1816262116.
    PubMed     Abstract available


    December 2018
  98. TOMINAGA K, Minato H, Murayama T, Sasahara A, et al
    Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells.
    Proc Natl Acad Sci U S A. 2018 Dec 26. pii: 1806851116.
    PubMed     Abstract available


  99. BOCCI F, Gearhart-Serna L, Boareto M, Ribeiro M, et al
    Toward understanding cancer stem cell heterogeneity in the tumor microenvironment.
    Proc Natl Acad Sci U S A. 2018 Dec 26. pii: 1815345116.
    PubMed     Abstract available


  100. TERAO C, Yoshifuji H, Matsumura T, Naruse TK, et al
    Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
    Proc Natl Acad Sci U S A. 2018;115:13045-13050.
    PubMed     Abstract available


  101. KAPLANOV I, Carmi Y, Kornetsky R, Shemesh A, et al
    Blocking IL-1beta reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
    Proc Natl Acad Sci U S A. 2018 Dec 13. pii: 1812266115.
    PubMed     Abstract available


  102. VOISIN T, Chiu IM
    Molecular link between itch and atopic dermatitis.
    Proc Natl Acad Sci U S A. 2018 Dec 11. pii: 1818879115.
    PubMed    


  103. TOKUYAMA M, Kong Y, Song E, Jayewickreme T, et al
    ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses.
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    DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.
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    IkappaBzeta is a key transcriptional regulator of IL-36-driven psoriasis-related gene expression in keratinocytes.
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