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Articles published in Am J Pathol

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Single Articles


    May 2021
  1. MEYER JM, Crumrine D, Schneider H, Dick A, et al
    Unbound Corneocyte Lipid Envelopes in 12R-Lipoxygenase Deficiency Support a Specific Role in Lipid-Protein Cross-Linking.
    Am J Pathol. 2021;191:921-929.
    PubMed     Abstract available


    March 2021
  2. SANSBURY BE, Li X, Wong B, Riley CO, et al
    PCTR1 enhances repair and bacterial clearance in skin wounds.
    Am J Pathol. 2021 Mar 6. pii: S0002-9440(21)00082.
    PubMed     Abstract available


    February 2021
  3. ANWAR T, Gonzalez ME, Kleer CG
    Non-canonical functions of the Polycomb group protein EZH2 in breast cancer.
    Am J Pathol. 2021 Feb 5. pii: S0002-9440(21)00044.
    PubMed     Abstract available


  4. VARIKUTI S, Verma C, Natarajan G, Oghumu S, et al
    MicroRNA155 plays a critical role in the pathogenesis of cutaneous Leishmania major infection by promoting a Th2 response and attenuating dendritic cell activity.
    Am J Pathol. 2021 Feb 1. pii: S0002-9440(21)00043.
    PubMed     Abstract available


    January 2021
  5. CHOI W, Yang AX, Sieve A, Kuo SH, et al
    Pulmonary Mycosis Drives Forkhead Box Protein A2 Degradation and Mucus Hypersecretion through Activation of the Spleen Tyrosine Kinase-Epidermal Growth Factor Receptor-AKT/Extracellular Signal-Regulated Kinase 1/2 Signaling.
    Am J Pathol. 2021;191:108-130.
    PubMed     Abstract available


  6. PILLING D, Karhadkar TR, Gomer RH
    High-Fat Diet-Induced Adipose Tissue and Liver Inflammation and Steatosis in Mice Are Reduced by Inhibiting Sialidases.
    Am J Pathol. 2021;191:131-143.
    PubMed     Abstract available


    December 2020
  7. LU N, Zhang M, Lu L, Liu YZ, et al
    Insulin-Induced Gene 2 Expression Is Associated with Breast Cancer Metastasis.
    Am J Pathol. 2020 Dec 13. pii: S0002-9440(20)30555.
    PubMed     Abstract available


  8. LOPEZ C, Gibert-Ramos A, Bosch R, Korzynska A, et al
    Differences in the immune response of the non-metastatic axillary lymph nodes between triple-negative and luminal A breast cancer surrogate subtypes.
    Am J Pathol. 2020 Dec 9. pii: S0002-9440(20)30549.
    PubMed     Abstract available


  9. WANG S, Zhang X, Wang H, Wang Y, et al
    Heat Shock Protein 27 Enhances SUMOylation of Heat Shock Protein B8 to Accelerate the Progression of Breast Cancer.
    Am J Pathol. 2020;190:2464-2477.
    PubMed     Abstract available


  10. PARRILLA CASTELLAR ER, Plichta JK, Davis R, Gonzalez-Hunt C, et al
    Somatic Mutations in LRRK2 Identify a Subset of Invasive Mammary Carcinomas Associated with High Mutation Burden.
    Am J Pathol. 2020;190:2478-2482.
    PubMed     Abstract available


    November 2020
  11. SARMA A, Gajan A, Kim S, Gurdziel K, et al
    RAD6B loss disrupts expression of melanoma phenotype in part by inhibiting WNT/beta-catenin signaling.
    Am J Pathol. 2020 Nov 9. pii: S0002-9440(20)30496.
    PubMed     Abstract available


    October 2020
  12. YANG Z, Zhang C, Che N, Feng Y, et al
    SET domain-containing 5 (SETD5) facilitates tumor growth and pulmonary metastasis through up-regulation of AKT1 signaling in breast cancer.
    Am J Pathol. 2020 Oct 28. pii: S0002-9440(20)30486.
    PubMed     Abstract available


    August 2020
  13. YAMAMOTO-FUKUDA T, Akiyama N, Kojima H
    L1CAM-ILK-YAP Mechanotransduction Drives Proliferative Activity of Epithelial Cells in Middle Ear Cholesteatoma.
    Am J Pathol. 2020;190:1667-1679.
    PubMed     Abstract available


    July 2020
  14. GASSENMAIER M, Rentschler M, Fehrenbacher B, Eigentler TK, et al
    Expression of DNA methyltransferase 1 is a hallmark of melanoma, correlates with response to BRAF and MEK inhibition and with proliferation in melanocytic tumors.
    Am J Pathol. 2020 Jul 14. pii: S0002-9440(20)30335.
    PubMed     Abstract available


  15. KATOH D, Kozuka Y, Noro A, Ogawa T, et al
    Tenascin-C induces phenotypic changes in fibroblasts to myofibroblasts with high contractility through the integrin alphavbeta1/TGF-beta/SMAD signaling axis in human breast cancer.
    Am J Pathol. 2020 Jul 7. pii: S0002-9440(20)30329.
    PubMed     Abstract available


    June 2020
  16. RASMUSSON A, Zilenaite D, Nestarenkaite A, Augulis R, et al
    Immunogradient Indicators for Antitumor Response Assessment by Automated Tumor-Stroma Interface Zone Detection.
    Am J Pathol. 2020;190:1309-1322.
    PubMed     Abstract available


    May 2020
  17. KOCAK A, Heselmeyer-Haddad K, Lischka A, Hirsch D, et al
    High levels of chromosomal copy number alterations and TP53 mutations correlate with poor outcome in younger breast cancer patients.
    Am J Pathol. 2020 May 13. pii: S0002-9440(20)30238.
    PubMed     Abstract available


    April 2020
  18. LE H, Gupta R, Hou L, Abousamra S, et al
    Utilizing Automated Breast Cancer Detection to Identify Spatial Distributions of Tumor Infiltrating Lymphocytes in Invasive Breast Cancer.
    Am J Pathol. 2020 Apr 8. pii: S0002-9440(20)30188.
    PubMed     Abstract available


  19. RUSSELL-GOLDMAN E, Murphy GF
    The Pathobiology of Skin Ageing: New Insights into an Old Dilemma.
    Am J Pathol. 2020 Apr 1. pii: S0002-9440(20)30142.
    PubMed     Abstract available


    March 2020
  20. MUNOZ-SILVESTRE A, Penades M, Selva L, Perez-Fuentes S, et al
    Pathogenesis of intradermal staphylococcal infections: rabbit experimental approach to natural Staphylococcus aureus skin infections.
    Am J Pathol. 2020 Mar 19. pii: S0002-9440(20)30128.
    PubMed     Abstract available


  21. SALHI A, Jordan AC, Bochaca II, Izsak A, et al
    Oxidative phosphorylation promotes primary melanoma invasion.
    Am J Pathol. 2020 Mar 3. pii: S0002-9440(20)30092.
    PubMed     Abstract available


    February 2020
  22. NELSON LJ, Wright HJ, Dinh NB, Nguyen KD, et al
    Src Kinase Is Biphosphorylated at Y416/Y527 and Activates the CUB-Domain Containing Protein 1/Protein Kinase C delta Pathway in a Subset of Triple-Negative Breast Cancers.
    Am J Pathol. 2020;190:484-502.
    PubMed     Abstract available


    January 2020
  23. OGAWA T, Ishitsuka Y, Inoue S, Nakamura Y, et al
    Nuclear factor erythroid 2-related factor 2 (Nrf2) regulates epidermal keratinization under psoriatic skin inflammation.
    Am J Pathol. 2020 Jan 14. pii: S0002-9440(20)30002.
    PubMed     Abstract available


    December 2019
  24. LOPEZ C, Bosch R, Orero G, Korzynska A, et al
    The immune response in non-metastatic axillary lymph nodes is associated with the presence of axillary metastasis and breast cancer patient outcome.
    Am J Pathol. 2019 Dec 19. pii: S0002-9440(19)30860.
    PubMed     Abstract available


  25. PIIPPONEN M, Nissinen L, Riihila P, Farshchian M, et al
    p53-regulated long non-coding RNA PRECSIT promotes progression of cutaneous squamous cell carcinoma via STAT3 signaling.
    Am J Pathol. 2019 Dec 12. pii: S0002-9440(19)30856.
    PubMed     Abstract available


    October 2019
  26. WU L, Awaji M, Saxena S, Varney ML, et al
    Interleukin17-CXCR2 axis facilitates breast cancer progression by up-regulating neutrophil recruitment.
    Am J Pathol. 2019 Oct 22. pii: S0002-9440(19)30768.
    PubMed     Abstract available


  27. TSANG M, Quesnel K, Vincent K, Hutchenreuther J, et al
    Insights into Fibroblast Plasticity: CCN2 Is Required for Activation of Cancer-Associated Fibroblasts in a Murine Model of Melanoma.
    Am J Pathol. 2019 Oct 11. pii: S0002-9440(19)30754.
    PubMed     Abstract available


  28. ZHANG Y, Liu F, Zhang C, Ren M, et al
    Non-SMC condensin I complex subunit D2 is a prognostic factor in triple-negative breast cancer for the ability to promote cell cycle and enhance invasion.
    Am J Pathol. 2019 Oct 11. pii: S0002-9440(19)30762.
    PubMed     Abstract available


  29. TURNER SD, Inghirami G, Miranda RN, Kadin ME, et al
    Cell of Origin and Immunological Events in the Pathogenesis of Breast Implant-Associated Anaplastic Large Cell Lymphoma.
    Am J Pathol. 2019 Oct 11. pii: S0002-9440(19)30753.
    PubMed     Abstract available


    September 2019
  30. QIN H, Lu S, Thangaraju M, Cowell JK, et al
    Wasf3 deficiency reveals involvement in metastasis in a mouse model of breast cancer.
    Am J Pathol. 2019 Sep 19. pii: S0002-9440(19)30716.
    PubMed     Abstract available


    August 2019
  31. ZHOU Y, Song KY, Giubellino A
    The role of MET in melanoma and melanocytic lesions.
    Am J Pathol. 2019 Aug 30. pii: S0002-9440(19)30703.
    PubMed     Abstract available


  32. VOLK-DRAPER L, Patel R, Bhattarai N, Yang J, et al
    Myeloid-Derived Lymphatic Endothelial Cell Progenitors Significantly Contribute to Lymphatic Metastasis in Clinical Breast Cancer.
    Am J Pathol. 2019 Aug 14. pii: S0002-9440(19)30662.
    PubMed     Abstract available


    June 2019
  33. ANDOH T, Akasaka C, Shimizu K, Lee JB, et al
    Involvement of alpha-Melanocyte-Stimulating Hormone-Thromboxane A2 System on Itching in Atopic Dermatitis.
    Am J Pathol. 2019 Jun 17. pii: S0002-9440(18)31174.
    PubMed     Abstract available


  34. BROOKS PJ, Glogauer M, McCulloch CA
    An Overview of the Derivation and Function of Multinucleated Giant Cells and Their Role in Pathologic Processes.
    Am J Pathol. 2019;189:1145-1158.
    PubMed     Abstract available


    May 2019
  35. YANG T, Zhang X, Chen A, Xiao Y, et al
    Progranulin Promotes Bleomycin-Induced Skin Sclerosis by Enhancing TGF-beta/Smad3 Signaling through Up-Regulation of TGF-beta Type I Receptor.
    Am J Pathol. 2019 May 17. pii: S0002-9440(18)30947.
    PubMed     Abstract available


    February 2019
  36. CHEN Q, Shi P, Wang D, Liu Q, et al
    Epidermis Activated Gsdma3 Enhances Thermogenesis of Brown Adipose Tissue through Interleukin-6/Stat3 Signaling.
    Am J Pathol. 2019 Feb 18. pii: S0002-9440(18)30592.
    PubMed     Abstract available


  37. WOODWARD AM, Lehoux S, Mantelli F, Di Zazzo A, et al
    Inflammatory Stress Causes N-Glycan Processing Deficiency in Ocular Autoimmune Disease.
    Am J Pathol. 2019;189:283-294.
    PubMed     Abstract available


  38. LI Q, van de Wetering K, Uitto J
    Pseudoxanthoma Elasticum as a Paradigm of Heritable Ectopic Mineralization Disorders: Pathomechanisms and Treatment Development.
    Am J Pathol. 2019;189:216-225.
    PubMed     Abstract available


    December 2018
  39. MUZUMDAR S, Hiebert H, Haertel E, Ben-Yehuda Greenwald M, et al
    Nrf2-mediated expansion of pilosebaceous cells accelerates cutaneous wound healing.
    Am J Pathol. 2018 Dec 26. pii: S0002-9440(18)30652.
    PubMed     Abstract available


    August 2018
  40. CARON JM, Han X, Contois L, Vary CPH, et al
    The HU177 Collagen Epitope Controls Melanoma Cell Migration and Experimental Metastasis by a CDK5/YAP-Dependent Mechanism.
    Am J Pathol. 2018 Aug 14. pii: S0002-9440(18)30253.
    PubMed     Abstract available


    July 2018
  41. ROMERO P, Benhamo V, Deniziaut G, Fuhrmann L, et al
    Medullary Breast Carcinoma, a Triple-Negative Breast Cancer Associated with BCLG Overexpression.
    Am J Pathol. 2018 Jul 31. pii: S0002-9440(17)31226.
    PubMed     Abstract available


    June 2018
  42. BORCHERDING N, Cole K, Kluz P, Jorgensen M, et al
    Reevaluating E-cadherin and beta-catenin: A pan-cancer proteomic approach with an emphasis on breast cancer.
    Am J Pathol. 2018 Jun 4. pii: S0002-9440(18)30113.
    PubMed     Abstract available


    March 2018
  43. MADSEN M, Hansen PR, Nielsen LB, Cardoso RM, et al
    Imiquimod-Induced Psoriasis-Like Skin Lesions Do Not Accelerate Atherosclerosis in Low Density Lipoprotein Receptor-Deficient Mice.
    Am J Pathol. 2018 Mar 12. pii: S0002-9440(17)30586.
    PubMed     Abstract available


    November 2017
  44. BENOIT T, Valera MC, Fontaine C, Buscato M, et al
    Estetrol, a Fetal Selective Estrogen Receptor Modulator, Acts on the Vagina of Mice through Nuclear Estrogen Receptor alpha Activation.
    Am J Pathol. 2017;187:2499-2507.
    PubMed     Abstract available


  45. LEITE DANTAS R, Brachvogel B, Schied T, Bergmeier V, et al
    The LIM-Only Protein Four and a Half LIM Domain Protein 2 Attenuates Development of Psoriatic Arthritis by Blocking Adam17-Mediated Tumor Necrosis Factor Release.
    Am J Pathol. 2017;187:2388-2398.
    PubMed     Abstract available


  46. WILLRODT AH, Beffinger M, Vranova M, Protsyuk D, et al
    Stromal Expression of Activated Leukocyte Cell Adhesion Molecule Promotes Lung Tumor Growth and Metastasis.
    Am J Pathol. 2017;187:2558-2569.
    PubMed     Abstract available


    October 2017
  47. SEMANGO G, Heinhuis B, Plantinga TS, Blokx WAM, et al
    Exploring the Role of IL-32 in human immunodeficiency virus-related Kaposi sarcoma.
    Am J Pathol. 2017 Oct 13. pii: S0002-9440(17)30362.
    PubMed     Abstract available



  48. This Month in AJP.
    Am J Pathol. 2017;187:2129.
    PubMed     Abstract available


  49. GEYER FC, Pareja F, Weigelt B, Rakha E, et al
    The Spectrum of Triple-Negative Breast Disease: High- and Low-Grade Lesions.
    Am J Pathol. 2017;187:2139-2151.
    PubMed     Abstract available


    September 2017
  50. ZHANG J, Corciulo C, Liu H, Wilder T, et al
    Adenosine A2a Receptor Blockade Diminishes Wnt/beta-Catenin Signaling in a Murine Model of Bleomycin-Induced Dermal Fibrosis.
    Am J Pathol. 2017;187:1935-1944.
    PubMed     Abstract available


    August 2017
  51. COLEMAN WB
    Next-Generation Breast Cancer Omics.
    Am J Pathol. 2017 Aug 16. pii: S0002-9440(17)30716.
    PubMed     Abstract available


  52. COLEMAN WB, Anders CK
    Discerning Clinical Responses in Breast Cancer Based On Molecular Signatures.
    Am J Pathol. 2017 Aug 16. pii: S0002-9440(17)30680.
    PubMed     Abstract available


  53. LAURIDSEN HM, Pellowe AS, Ramanathan A, Liu R, et al
    Tumor Necrosis Factor-alpha and IL-17A Activation Induces Pericyte-Mediated Basement Membrane Remodeling in Human Neutrophilic Dermatoses.
    Am J Pathol. 2017;187:1893-1906.
    PubMed     Abstract available


    July 2017
  54. MARDAMSHINA M, Geiger T
    Next-Generation Proteomics and Its Application to Clinical Breast Cancer Research.
    Am J Pathol. 2017 Jul 20. pii: S0002-9440(17)30035.
    PubMed     Abstract available


  55. DAVALOS V, Martinez-Cardus A, Esteller M
    The Epigenomic Revolution in Breast Cancer: From Single-Gene to Genome-Wide Next-Generation Approaches.
    Am J Pathol. 2017 Jul 19. pii: S0002-9440(17)30582.
    PubMed     Abstract available


  56. MAROTTI JD, de Abreu FB, Wells WA, Tsongalis GJ, et al
    Triple Negative Breast Cancer: Next-Generation Sequencing for Target Identification.
    Am J Pathol. 2017 Jul 19. pii: S0002-9440(17)30291.
    PubMed     Abstract available


  57. ROSENBAUM JN, Weisman P
    The Evolving Role of Companion Diagnostics for Breast Cancer in an Era of Next-Generation Omics.
    Am J Pathol. 2017 Jul 18. pii: S0002-9440(17)30069.
    PubMed     Abstract available


  58. RUSSNES HG, Lingjaerde OC, Borresen-Dale AL, Caldas C, et al
    Breast cancer molecular stratification- from intrinsic subtypes to integrative clusters.
    Am J Pathol. 2017 Jul 18. pii: S0002-9440(17)30134.
    PubMed     Abstract available


  59. DOEBAR SC, Sieuwerts AM, de Weerd V, Stoop H, et al
    Gene Expression Differences between Ductal Carcinoma in Situ with and without Progression to Invasive Breast Cancer.
    Am J Pathol. 2017;187:1648-1655.
    PubMed     Abstract available


  60. CIANFARANI F, Zambruno G, Castiglia D, Odorisio T, et al
    Pathomechanisms of Altered Wound Healing in Recessive Dystrophic Epidermolysis Bullosa.
    Am J Pathol. 2017;187:1445-1453.
    PubMed     Abstract available


    June 2017
  61. KISPERT S, Schwartz T, McHowat J
    Cigarette Smoke Regulates Calcium-Independent Phospholipase A2 Metabolic Pathways in Breast Cancer.
    Am J Pathol. 2017 Jun 12. pii: S0002-9440(17)30032.
    PubMed     Abstract available


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