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Articles published in PLoS Comput Biol

Retrieve available abstracts of 36 articles:
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Single Articles


    September 2026
  1. HUANG ZH, Xu Z, Hu P
    Spatially guided translation from histology images to transcriptomic profiles using foundation model-driven contrastive learning.
    PLoS Comput Biol. 2026;22:e1014762.
    PubMed     Abstract available


  2. YANG C, Liao Y, Sheng Y, Jiao F, et al
    Integrating zero-inflation correction and transcriptional kinetics for single-cell transcriptomic analysis.
    PLoS Comput Biol. 2026;22:e1014779.
    PubMed     Abstract available


    August 2026
  3. CAMACHO LQ, Fallahi-Sichani M
    Systematic multivariate analysis of chromatin complex dependencies reveals Set1C/COMPASS as a melanoma-enriched epigenetic vulnerability.
    PLoS Comput Biol. 2026;22:e1014018.
    PubMed     Abstract available


    July 2026
  4. STANCIU A, Gombos A, Agostinetto E, Vincent D, et al
    ALFAssay: A feed?forward neural network for quantitative fragmentomics?based ctDNA profiling in breast cancer.
    PLoS Comput Biol. 2026;22:e1014505.
    PubMed     Abstract available


    May 2026
  5. LEYVA A, Akbar AR, Niazi MKK
    Predicting protein cascade expression from H&E images.
    PLoS Comput Biol. 2026;22:e1014262.
    PubMed     Abstract available


  6. HESS JM, Dzeng RK, Ilies I, Schapiro D, et al
    MIAAIM: Multi-omics image integration with dimensional reduction for tissue state mapping.
    PLoS Comput Biol. 2026;22:e1014274.
    PubMed     Abstract available


    March 2026
  7. VEITH T, Beck RJ, Brown JS, Andor N, et al
    Inverse game theory characterizes frequency-dependent selection driven by karyotypic diversity in triple negative breast cancer.
    PLoS Comput Biol. 2026;22:e1013897.
    PubMed     Abstract available


  8. HUO X, Duan X, Huang X, Xue L, et al
    An integrative analysis reveals the mechanism of plastic stabilizers inducing breast cancer.
    PLoS Comput Biol. 2026;22:e1014025.
    PubMed     Abstract available


  9. MORUNO-CUENCA A, Picart-Armada S, Bogle R, Fox J, et al
    singIST: An integrative method for comparative single-cell transcriptomics between disease models and humans.
    PLoS Comput Biol. 2026;22:e1014002.
    PubMed     Abstract available


  10. SU JC, Lee CL, Yang FW, Chen YC, et al
    Network-based exploration of 4-(phenylsulfonyl)morpholine molecules for metastatic triple-negative breast cancer suppression.
    PLoS Comput Biol. 2026;22:e1014132.
    PubMed     Abstract available


  11. DAVYDZENKA K, Caravagna G, Sanguinetti G
    Extending differential gene expression testing to handle genome aneuploidy in cancer.
    PLoS Comput Biol. 2026;22:e1014134.
    PubMed     Abstract available


    February 2026
  12. WANG Y, Zang C, Li Z, Guo CC, et al
    A comparative study of statistical methods for identifying differentially expressed genes in spatial transcriptomics.
    PLoS Comput Biol. 2026;22:e1013956.
    PubMed     Abstract available


    January 2026
  13. SANCERE L, Lorenz C, Helbig D, Persa OD, et al
    Histo-Miner: Deep learning based tissue features extraction pipeline from H&E whole slide images of cutaneous squamous cell carcinoma.
    PLoS Comput Biol. 2026;22:e1013907.
    PubMed     Abstract available


  14. JI T, Yang B, Wang M, Ji H, et al
    AugGCL: Multimodal graph learning for spatial transcriptomics analysis with enhanced gene and morphological data.
    PLoS Comput Biol. 2026;22:e1013912.
    PubMed     Abstract available


    December 2025
  15. HAN C, Song Z, Xu Z, Chen J, et al
    MAGNET: Multi-view graph autoencoder with cell-gene attention for cell interaction network reconstruction from spatial transcriptomics.
    PLoS Comput Biol. 2025;21:e1013810.
    PubMed     Abstract available


    November 2025
  16. FAHMI NA, Cheng S, Overstreet J, Song Q, et al
    IPScan: Detecting novel intronic PolyAdenylation events with RNA-seq data.
    PLoS Comput Biol. 2025;21:e1013668.
    PubMed     Abstract available


    October 2025
  17. MATACHE A, Lima-Junior JR, Kuznetsov M, Urbaniak K, et al
    Ligand discrimination in immune cells: Signal processing insights into immune dysfunction in ER+ breast cancer.
    PLoS Comput Biol. 2025;21:e1013615.
    PubMed     Abstract available


    September 2025
  18. NOUIRA A, Azencott CA
    Sparse multitask group Lasso for genome-wide association studies.
    PLoS Comput Biol. 2025;21:e1012734.
    PubMed     Abstract available


    August 2025
  19. YAVUZ BR, Sahin U, Jang H, Nussinov R, et al
    Mutations in tumor signaling, metastases, and synthetic lethality establish distinct patterns.
    PLoS Comput Biol. 2025;21:e1013351.
    PubMed     Abstract available


    May 2025
  20. HOPFL S, Ozverin M, Nowack H, Tamas R, et al
    Integrated mathematical and experimental modeling uncovers enhanced EMT plasticity upon loss of the DLC1 tumor suppressor.
    PLoS Comput Biol. 2025;21:e1013076.
    PubMed     Abstract available


    April 2025
  21. NOURBAKHSH M, Zheng Y, Noor H, Chen H, et al
    Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight.
    PLoS Comput Biol. 2025;21:e1012999.
    PubMed     Abstract available


  22. STAPLEY JN, Hamley JID, Basanez MG, Walker M, et al
    Modelling transmission thresholds and hypoendemic stability for onchocerciasis elimination.
    PLoS Comput Biol. 2025;21:e1013026.
    PubMed     Abstract available


    February 2025
  23. SAKAI SA, Nomura R, Nagasawa S, Chi S, et al
    SpatialKNifeY (SKNY): Extending from spatial domain to surrounding area to identify microenvironment features with single-cell spatial omics data.
    PLoS Comput Biol. 2025;21:e1012854.
    PubMed     Abstract available


  24. ZHAN X, Xu Q, Zheng Y, Lu G, et al
    Reliability-enhanced data cleaning in biomedical machine learning using inductive conformal prediction.
    PLoS Comput Biol. 2025;21:e1012803.
    PubMed     Abstract available


    January 2025
  25. SHI X, Wang X, Jin L, Halakivi-Clarke L, et al
    Bayesian identification of differentially expressed isoforms using a novel joint model of RNA-seq data.
    PLoS Comput Biol. 2025;21:e1012750.
    PubMed     Abstract available


    November 2024
  26. HUANG HY, Zhang FW, Yu J, Xiao YH, et al
    A computational analysis of the oncogenic and anti-tumor immunity role of P4HA3 in human cancers.
    PLoS Comput Biol. 2024;20:e1012284.
    PubMed     Abstract available


    October 2024
  27. CHEN L, Huang ZH, Sun Y, Domaratzki M, et al
    Conditional probabilistic diffusion model driven synthetic radiogenomic applications in breast cancer.
    PLoS Comput Biol. 2024;20:e1012490.
    PubMed     Abstract available


    September 2024
  28. SYLLA A, Chevillon C, Djidjiou-Demasse R, Seydi O, et al
    Understanding the transmission of bacterial agents of sapronotic diseases using an ecosystem-based approach: A first spatially realistic metacommunity model.
    PLoS Comput Biol. 2024;20:e1012435.
    PubMed     Abstract available


    July 2024
  29. NEVAREZ AJ, Mudla A, Diaz SA, Hao N, et al
    Using deep learning to decipher the impact of telomerase promoter mutations on the dynamic metastatic morpholome.
    PLoS Comput Biol. 2024;20:e1012271.
    PubMed     Abstract available


    June 2024
  30. XIE X, Sinha S
    Quantitative estimates of the regulatory influence of long non-coding RNAs on global gene expression variation using TCGA breast cancer transcriptomic data.
    PLoS Comput Biol. 2024;20:e1012103.
    PubMed     Abstract available


  31. VANDERDOES J, Marceaux C, Yokote K, Asselin-Labat ML, et al
    Using random forests to uncover the predictive power of distance-varying cell interactions in tumor microenvironments.
    PLoS Comput Biol. 2024;20:e1011361.
    PubMed     Abstract available


  32. DIMITRIOU NM, Flores-Torres S, Kyriakidou M, Kinsella JM, et al
    Cancer cell sedimentation in 3D cultures reveals active migration regulated by self-generated gradients and adhesion sites.
    PLoS Comput Biol. 2024;20:e1012112.
    PubMed     Abstract available


  33. PERRONE MC, Lerner MG, Dunworth M, Ewald AJ, et al
    Prioritizing drug targets by perturbing biological network response functions.
    PLoS Comput Biol. 2024;20:e1012195.
    PubMed     Abstract available


    May 2024
  34. BENZEKRY S, Mastri M, Nicolo C, Ebos JML, et al
    Machine-learning and mechanistic modeling of metastatic breast cancer after neoadjuvant treatment.
    PLoS Comput Biol. 2024;20:e1012088.
    PubMed     Abstract available


    April 2024
  35. LIU C, Xiao K, Yu C, Lei Y, et al
    A probabilistic knowledge graph for target identification.
    PLoS Comput Biol. 2024;20:e1011945.
    PubMed     Abstract available


    March 2024
  36. VALEGA-MACKENZIE W, Rodriguez Messan M, Yogurtcu ON, Nukala U, et al
    Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine.
    PLoS Comput Biol. 2024;20:e1011247.
    PubMed     Abstract available


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