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Articles published in Intensive Care Med

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Single Articles


    July 2021

  1. Reducing the global burden of sepsis: a positive legacy for the COVID-19 pandemic?
    Intensive Care Med. 2021;47:733-736.
    PubMed    


    May 2021
  2. LITTON E, Currie A, Raby E
    Probiotics and sepsis: separating the signal from the noise.
    Intensive Care Med. 2021 May 20. pii: 10.1007/s00134-021-06427.
    PubMed    


    March 2021
  3. PELLEGRINI JAS, Schwarz P, Parolo E, Cremonese RV, et al
    All that glitters is not gold: an unusual presentation of S. aureus sepsis during ECMO.
    Intensive Care Med. 2021 Mar 21. pii: 10.1007/s00134-021-06366.
    PubMed    


  4. DAVID S, Bode C, Putensen C, Welte T, et al
    Adjuvant therapeutic plasma exchange in septic shock.
    Intensive Care Med. 2021;47:352-354.
    PubMed    


    February 2021
  5. THOMPSON K, Venkatesh B, Hammond N, Taylor C, et al
    Sex differences in response to adjunctive corticosteroid treatment for patients with septic shock.
    Intensive Care Med. 2021;47:246-248.
    PubMed    


    January 2021
  6. BUETTI N, Ruckly S, de Montmollin E, Reignier J, et al
    COVID-19 increased the risk of ICU-acquired bloodstream infections: a case-cohort study from the multicentric OUTCOMEREA network.
    Intensive Care Med. 2021 Jan 27. pii: 10.1007/s00134-021-06346.
    PubMed     Abstract available


    September 2020
  7. FUJII T, Fowler R, Vincent JL
    Vitamin C and thiamine for sepsis: time to go back to fundamental principles.
    Intensive Care Med. 2020 Sep 18. pii: 10.1007/s00134-020-06242.
    PubMed    


    August 2020

  8. Could lung bacterial dysbiosis predict ICU mortality in patients with extra-pulmonary sepsis? A proof-of-concept study.
    Intensive Care Med. 2020 Aug 7. pii: 10.1007/s00134-020-06190.
    PubMed    


    July 2020
  9. AURIEMMA CL, Delucchi K, Liu KD, Calfee CS, et al
    The attributable mortality of acute respiratory distress syndrome.
    Intensive Care Med. 2020;46:1510-1511.
    PubMed    


  10. DE GROOTH HJ, Tuinman PR, Girbes ARJ
    The attributable mortality of acute respiratory distress syndrome.
    Intensive Care Med. 2020;46:1508-1509.
    PubMed    


    June 2020
  11. LANE DJ, Wunsch H, Saskin R, Cheskes S, et al
    Correction to: Epidemiology and patient predictors of infection and sepsis in the prehospital setting.
    Intensive Care Med. 2020 Jun 30. pii: 10.1007/s00134-020-06164.
    PubMed     Abstract available


  12. MARKWART R, Saito H, Harder T, Tomczyk S, et al
    Epidemiology and burden of sepsis acquired in hospitals and intensive care units: a systematic review and meta-analysis.
    Intensive Care Med. 2020 Jun 26. pii: 10.1007/s00134-020-06106.
    PubMed     Abstract available


  13. FLEISCHMANN-STRUZEK C, Mellhammar L, Rose N, Cassini A, et al
    Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis.
    Intensive Care Med. 2020 Jun 22. pii: 10.1007/s00134-020-06151.
    PubMed     Abstract available


  14. TISSIERES P, Peters MJ, Kissoon N, Weiss SL, et al
    Might the surviving sepsis campaign international guidelines be less confusing? Authors' reply.
    Intensive Care Med. 2020 Jun 22. pii: 10.1007/s00134-020-06158.
    PubMed    


  15. UHEL F, Peters-Sengers H, Falahi F, Scicluna BP, et al
    Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study.
    Intensive Care Med. 2020 Jun 8. pii: 10.1007/s00134-020-06119.
    PubMed     Abstract available


  16. MONNERET G, Cour M, Viel S, Venet F, et al
    Coronavirus disease 2019 as a particular sepsis: a 2-week follow-up of standard immunological parameters in critically ill patients.
    Intensive Care Med. 2020 Jun 2. pii: 10.1007/s00134-020-06123.
    PubMed    


    May 2020
  17. LANE DJ, Wunsch H, Saskin R, Cheskes S, et al
    Epidemiology and patient predictors of infection and sepsis in the prehospital setting.
    Intensive Care Med. 2020 May 28. pii: 10.1007/s00134-020-06093.
    PubMed     Abstract available


  18. BRIASSOULIS G, Briassoulis P, Miliaraki M, Ilia S, et al
    Might the pediatric surviving sepsis campaign international guidelines be less confusing?
    Intensive Care Med. 2020 May 25. pii: 10.1007/s00134-020-06108.
    PubMed    


  19. REN D, Ren C, Yao RQ, Feng YW, et al
    Clinical features and development of sepsis in patients infected with SARS-CoV-2: a retrospective analysis of 150 cases outside Wuhan, China.
    Intensive Care Med. 2020 May 15. pii: 10.1007/s00134-020-06084.
    PubMed    


  20. REINHART K, Daniels RD, Schwarzkopf D, Kissoon N, et al
    Sepsis hysteria: facts versus fiction.
    Intensive Care Med. 2020 May 4. pii: 10.1007/s00134-020-06001.
    PubMed    


    April 2020
  21. HELMS J, Perner A
    Focus on sepsis.
    Intensive Care Med. 2020 Apr 23. pii: 10.1007/s00134-020-06038.
    PubMed    


  22. STOLK RF, Kox M, Pickkers P
    Noradrenaline drives immunosuppression in sepsis: clinical consequences.
    Intensive Care Med. 2020 Apr 8. pii: 10.1007/s00134-020-06025.
    PubMed    


    March 2020
  23. ALHAZZANI W, Moller MH, Arabi YM, Loeb M, et al
    Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19).
    Intensive Care Med. 2020 Mar 28. pii: 10.1007/s00134-020-06022.
    PubMed     Abstract available


  24. AURIEMMA CL, Zhuo H, Delucchi K, Deiss T, et al
    Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis.
    Intensive Care Med. 2020 Mar 23. pii: 10.1007/s00134-020-06010.
    PubMed     Abstract available


  25. ELIZABETH WILCOX M, Donnelly JP, Lone NI
    Correction to: Understanding gender disparities in outcomes after sepsis.
    Intensive Care Med. 2020 Mar 13. pii: 10.1007/s00134-020-06006.
    PubMed     Abstract available


  26. ZHANG W
    Imaging changes in severe COVID-19 pneumonia.
    Intensive Care Med. 2020 Mar 3. pii: 10.1007/s00134-020-05976.
    PubMed    


    February 2020
  27. BRANT EB, Martin-Gill C, Callaway CW, Angus DC, et al
    Prehospital identification of community sepsis using biomarkers of host response.
    Intensive Care Med. 2020 Feb 24. pii: 10.1007/s00134-020-05975.
    PubMed    


  28. HERNANDEZ G, Kattan E, Ospina-Tascon G, Bakker J, et al
    Capillary refill time status could identify different clinical phenotypes among septic shock patients fulfilling Sepsis-3 criteria: a post hoc analysis of ANDROMEDA-SHOCK trial.
    Intensive Care Med. 2020 Feb 19. pii: 10.1007/s00134-020-05960.
    PubMed    


  29. ELIZABETH WILCOX M, Donnelly JP, Lone NI
    Understanding gender disparities in outcomes after sepsis.
    Intensive Care Med. 2020 Feb 18. pii: 10.1007/s00134-020-05961.
    PubMed    


  30. TAYLOR MD, Tibby SM
    Sometimes more is not always better: ScvO2 monitoring in pediatric sepsis.
    Intensive Care Med. 2020 Feb 11. pii: 10.1007/s00134-020-05946.
    PubMed    


  31. GARNACHO-MONTERO J, Martin-Loeches I
    Clinical management of sepsis can be improved by artificial intelligence: no.
    Intensive Care Med. 2020 Feb 3. pii: 10.1007/s00134-020-05947.
    PubMed    


  32. WEISS SL, Peters MJ, Alhazzani W, Agus MSD, et al
    Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.
    Intensive Care Med. 2020;46.
    PubMed     Abstract available


  33. WEISS SL, Peters MJ, Alhazzani W, Agus MSD, et al
    Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.
    Intensive Care Med. 2020;46.
    PubMed    


  34. TIMSIT JF, Ruppe E, Barbier F, Tabah A, et al
    Bloodstream infections in critically ill patients: an expert statement.
    Intensive Care Med. 2020;46:266-284.
    PubMed     Abstract available


  35. RELLO J, Campogiani L, Eshwara VK
    Understanding resistance in enterococcal infections.
    Intensive Care Med. 2020;46:353-356.
    PubMed    


    January 2020
  36. SHANKAR-HARI M, Saha R, Wilson J, Prescott HC, et al
    Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis.
    Intensive Care Med. 2020 Jan 23. pii: 10.1007/s00134-019-05908.
    PubMed     Abstract available


  37. SUNDEN-CULLBERG J, Nilsson A, Inghammar M
    Sex-based differences in ED management of critically ill patients with sepsis: a nationwide cohort study.
    Intensive Care Med. 2020 Jan 23. pii: 10.1007/s00134-019-05910.
    PubMed     Abstract available


  38. FLEUREN LM, Klausch TLT, Zwager CL, Schoonmade LJ, et al
    Machine learning for the prediction of sepsis: a systematic review and meta-analysis of diagnostic test accuracy.
    Intensive Care Med. 2020 Jan 21. pii: 10.1007/s00134-019-05872.
    PubMed     Abstract available


  39. ROIMI M, Neuberger A, Shrot A, Paul M, et al
    Early diagnosis of bloodstream infections in the intensive care unit using machine-learning algorithms.
    Intensive Care Med. 2020 Jan 7. pii: 10.1007/s00134-019-05876.
    PubMed     Abstract available


  40. SANKAR J, Singh M, Kumar K, Sankar MJ, et al
    'Intermittent' versus 'continuous' ScvO2 monitoring in children with septic shock: a randomised, non-inferiority trial.
    Intensive Care Med. 2020;46:82-92.
    PubMed     Abstract available


  41. BOSCH NA, Teja B, Wunsch H, Walkey AJ, et al
    Characterization and validation of a novel measure of septic shock severity.
    Intensive Care Med. 2020;46:135-137.
    PubMed    


    December 2019
  42. KOMOROWSKI M
    Clinical management of sepsis can be improved by artificial intelligence: yes.
    Intensive Care Med. 2019 Dec 13. pii: 10.1007/s00134-019-05898.
    PubMed    


    November 2019
  43. PERNER A, De Jong A, Shankar-Hari M
    Trials on oxygen supplementation in sepsis: better late than never.
    Intensive Care Med. 2019 Nov 26. pii: 10.1007/s00134-019-05874.
    PubMed    


  44. YOUNG P, Mackle D, Bellomo R, Bailey M, et al
    Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX).
    Intensive Care Med. 2019 Nov 20. pii: 10.1007/s00134-019-05857.
    PubMed     Abstract available


    October 2019
  45. BLOT S, Antonelli M, Arvaniti K, Blot K, et al
    Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials Group Project.
    Intensive Care Med. 2019 Oct 29. pii: 10.1007/s00134-019-05819.
    PubMed     Abstract available


  46. SHANKAR-HARI M, Fish M, Azoulay E
    Should we consider blocking the inhibitory immune checkpoint molecules for treating T cell exhaustion in sepsis?
    Intensive Care Med. 2019 Oct 28. pii: 10.1007/s00134-019-05814.
    PubMed    


  47. HOTCHKISS RS, Colston E, Yende S, Crouser ED, et al
    Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab.
    Intensive Care Med. 2019;45:1360-1371.
    PubMed     Abstract available


    September 2019
  48. KLEINPELL R, Blot S, Boulanger C, Fulbrook P, et al
    International critical care nursing considerations and quality indicators for the 2017 surviving sepsis campaign guidelines.
    Intensive Care Med. 2019 Sep 18. pii: 10.1007/s00134-019-05780.
    PubMed    


  49. VAN DER WEERT S, Lansink PJ, Vermeijden JW, Cornet AD, et al
    Rare metastatic seeding: endogenous endophtalmitis in Staphylococcus aureus sepsis.
    Intensive Care Med. 2019 Sep 3. pii: 10.1007/s00134-019-05762.
    PubMed    


    August 2019
  50. DARGENT A, Pais De Barros JP, Ksiazek E, Fournel I, et al
    Improved quantification of plasma lipopolysaccharide (LPS) burden in sepsis using 3-hydroxy myristate (3HM): a cohort study.
    Intensive Care Med. 2019 Aug 26. pii: 10.1007/s00134-019-05749.
    PubMed    


  51. SCHETZ M, Bein T
    When more could be industry-driven: the case of the extracorporeal treatment of sepsis.
    Intensive Care Med. 2019 Aug 13. pii: 10.1007/s00134-019-05728.
    PubMed    


    July 2019
  52. MOLLER MH, Alhazzani W, Shankar-Hari M
    Focus on sepsis.
    Intensive Care Med. 2019 Jul 2. pii: 10.1007/s00134-019-05680.
    PubMed    


  53. CASTELA FORTE J, Perner A, van der Horst ICC
    The use of clustering algorithms in critical care research to unravel patient heterogeneity.
    Intensive Care Med. 2019;45:1025-1028.
    PubMed    


    June 2019
  54. BLOT S, Poulakou G, Timsit JF
    Catheter-associated bloodstream infection rates: how low can you go?
    Intensive Care Med. 2019;45:896-897.
    PubMed    


  55. YOUNG PJ, Delaney A, Venkatesh B
    Vasopressin in septic shock: what we know and where to next?
    Intensive Care Med. 2019;45:902-903.
    PubMed    


  56. NAGENDRAN M, Russell JA, Walley KR, Brett SJ, et al
    Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials.
    Intensive Care Med. 2019;45:844-855.
    PubMed     Abstract available


  57. EGGIMANN P, Pagani JL, Dupuis-Lozeron E, Ms BE, et al
    Sustained reduction of catheter-associated bloodstream infections with enhancement of catheter bundle by chlorhexidine dressings over 11 years.
    Intensive Care Med. 2019;45:823-833.
    PubMed     Abstract available


  58. MARTIN-LOECHES I, Antonelli M, Cuenca-Estrella M, Dimopoulos G, et al
    ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients.
    Intensive Care Med. 2019;45:789-805.
    PubMed     Abstract available


    May 2019
  59. DUCLOS G, Cantaloube M, Medam S, Resseguier N, et al
    Preliminary results of synergy between norepinephrine and terlipressin during septic shock.
    Intensive Care Med. 2019;45:730-732.
    PubMed    


    April 2019
  60. DE BACKER D, Cecconi M, Lipman J, Machado F, et al
    Challenges in the management of septic shock: a narrative review.
    Intensive Care Med. 2019;45:420-433.
    PubMed     Abstract available


  61. PAPAROUPA M, Yan Y, Moller M, Schuppert F, et al
    Nasogastric tube ending in the right pleura of an intubated patient.
    Intensive Care Med. 2019;45:523-524.
    PubMed    


    February 2019
  62. CLERE-JEHL R, Merdji H, Derhy D, Helms J, et al
    Blindness as an uncommon complication of Streptococcus pneumoniae systemic infection.
    Intensive Care Med. 2019;45:263-265.
    PubMed    


  63. BOS LDJ, Azoulay E, Martin-Loeches I
    Future of the ICU: finding treatable needles in the data haystack.
    Intensive Care Med. 2019;45:240-242.
    PubMed    


    January 2019
  64. BRIASSOULIS G, Briassoulis P, Miliaraki M, Ilia S, et al
    Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on "Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study".
    Intensive Care Med. 2019 Jan 7. pii: 10.1007/s00134-018-5451.
    PubMed    


    December 2018
  65. PICKKERS P, Russell JA
    Treatment with a polymyxin B filter to capture endotoxin in sepsis patients: is there a signal for therapeutic efficacy?
    Intensive Care Med. 2018 Dec 3. pii: 10.1007/s00134-018-5481.
    PubMed    


  66. SWENSON ER, Porcher R, Piagnerelli M
    Iron deficiency and infection: another pathway to explore in critically ill patients?
    Intensive Care Med. 2018;44:2260-2262.
    PubMed    


    November 2018
  67. MALLAT J, Reddi BJ
    Do not abandon monitoring the central venous pressure during fluid resuscitation of septic shock patients.
    Intensive Care Med. 2018;44:2012-2013.
    PubMed    


    October 2018
  68. MACDONALD SPJ, Keijzers G, Taylor DM, Kinnear F, et al
    Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial.
    Intensive Care Med. 2018 Oct 31. pii: 10.1007/s00134-018-5433.
    PubMed     Abstract available


  69. REILLY JP, Wang F, Jones TK, Palakshappa JA, et al
    Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis.
    Intensive Care Med. 2018 Oct 21. pii: 10.1007/s00134-018-5328.
    PubMed     Abstract available


  70. TIMSIT JF, Ruppe E, Ferrer R
    Focus on sepsis: new concepts and findings in sepsis care.
    Intensive Care Med. 2018 Oct 10. pii: 10.1007/s00134-018-5406.
    PubMed    


  71. SHANKAR-HARI M, Datta D, Wilson J, Assi V, et al
    Early PREdiction of sepsis using leukocyte surface biomarkers: the ExPRES-sepsis cohort study.
    Intensive Care Med. 2018 Oct 5. pii: 10.1007/s00134-018-5389.
    PubMed     Abstract available


  72. SINHA P, Delucchi KL, Thompson BT, McAuley DF, et al
    Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study.
    Intensive Care Med. 2018 Oct 5. pii: 10.1007/s00134-018-5378.
    PubMed     Abstract available


  73. FLEISCHMANN-STRUZEK C, Mikolajetz A, Schwarzkopf D, Cohen J, et al
    Challenges in assessing the burden of sepsis and understanding the inequalities of sepsis outcomes between National Health Systems: secular trends in sepsis and infection incidence and mortality in Germany.
    Intensive Care Med. 2018 Oct 4. pii: 10.1007/s00134-018-5377.
    PubMed     Abstract available


    September 2018
  74. KAPLAN JM, Zingarelli B, Krallman K, Tang Girdwood S, et al
    Phase 1 safety and pharmacokinetic study on the use of pioglitazone in critically ill patients with sepsis: a randomized clinical trial.
    Intensive Care Med. 2018 Sep 25. pii: 10.1007/s00134-018-5374.
    PubMed    


  75. LAVILLEGRAND JR, Dumas G, Bige N, Zafimahazo D, et al
    Should we treat mild hypotension in septic patients in the absence of peripheral tissue hypoperfusion?
    Intensive Care Med. 2018;44:1593-1594.
    PubMed    


    August 2018
  76. LUECK C, Stadler M, Koenecke C, Hoeper MM, et al
    Improved short- and long-term outcome of allogeneic stem cell recipients admitted to the intensive care unit: a retrospective longitudinal analysis of 942 patients.
    Intensive Care Med. 2018 Aug 23. pii: 10.1007/s00134-018-5347.
    PubMed     Abstract available


  77. LAW AC, Sahetya S, Walkey AJ, Delaney A, et al
    Low-dose corticosteroids and septic shock resolution: implications for randomized trial design?
    Intensive Care Med. 2018;44:1366-1367.
    PubMed    


  78. MOHUS RM, Paulsen J, Gustad L, Askim A, et al
    Association of iron status with the risk of bloodstream infections: results from the prospective population-based HUNT Study in Norway.
    Intensive Care Med. 2018;44:1276-1283.
    PubMed     Abstract available


    July 2018
  79. KERRIGAN SW, Martin-Loeches I
    Public awareness of sepsis is still poor: we need to do more.
    Intensive Care Med. 2018 Jul 19. pii: 10.1007/s00134-018-5307.
    PubMed    


  80. HODGSON CL, Walsh TS, Lone N
    The long road home: are outcomes different for patients with sepsis?
    Intensive Care Med. 2018 Jul 18. pii: 10.1007/s00134-018-5301.
    PubMed    


  81. COOPERSMITH CM, De Backer D, Deutschman CS, Ferrer R, et al
    Surviving sepsis campaign: research priorities for sepsis and septic shock.
    Intensive Care Med. 2018 Jul 3. pii: 10.1007/s00134-018-5175.
    PubMed     Abstract available


  82. RYGARD SL, Butler E, Granholm A, Moller MH, et al
    Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis.
    Intensive Care Med. 2018;44:1003-1016.
    PubMed     Abstract available


    June 2018
  83. PARLATO M, Philippart F, Rouquette A, Moucadel V, et al
    Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study.
    Intensive Care Med. 2018 Jun 30. pii: 10.1007/s00134-018-5228.
    PubMed     Abstract available


  84. THOMPSON K, Taylor C, Jan S, Li Q, et al
    Health-related outcomes of critically ill patients with and without sepsis.
    Intensive Care Med. 2018 Jun 27. pii: 10.1007/s00134-018-5274.
    PubMed     Abstract available


  85. SINGH K, Mayo P
    Transthoracic echocardiography and mortality in sepsis: are we there yet?
    Intensive Care Med. 2018 Jun 25. pii: 10.1007/s00134-018-5261.
    PubMed    


  86. MAHLA RS, Vincent JL, Sakr Y
    Sepsis is a global burden to human health: incidences are underrepresented : Discussion on " Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)".
    Intensive Care Med. 2018 Jun 19. pii: 10.1007/s00134-018-5239.
    PubMed    


  87. TEXTORIS J, Gordon AC
    Sepsis: who will shoot first? Pharma or diagnostics?
    Intensive Care Med. 2018 Jun 14. pii: 10.1007/s00134-018-5234.
    PubMed    


  88. ANNANE D, Ouanes-Besbes L, de Backer D, DU B, et al
    A global perspective on vasoactive agents in shock.
    Intensive Care Med. 2018;44:833-846.
    PubMed     Abstract available


    May 2018
  89. WENG L, Zeng XY, Yin P, Wang LJ, et al
    Sepsis-related mortality in China: a descriptive analysis.
    Intensive Care Med. 2018 May 30. pii: 10.1007/s00134-018-5203.
    PubMed     Abstract available


  90. FENG M, McSparron JI, Kien DT, Stone DJ, et al
    Transthoracic echocardiography and mortality in sepsis: analysis of the MIMIC-III database.
    Intensive Care Med. 2018 May 28. pii: 10.1007/s00134-018-5208.
    PubMed     Abstract available


  91. MONNIER-CHOLLEY L, Roux A, Pacanowski J, Arrive L, et al
    Myocardial calcifications following sepsis.
    Intensive Care Med. 2018 May 14. pii: 10.1007/s00134-018-5168.
    PubMed    


  92. HERNANDEZ G, Bellomo R, Bakker J
    The ten pitfalls of lactate clearance in sepsis.
    Intensive Care Med. 2018 May 12. pii: 10.1007/s00134-018-5213.
    PubMed    


  93. MANKOWSKI RT, Yende S, Angus DC
    Long-term impact of sepsis on cardiovascular health.
    Intensive Care Med. 2018 May 8. pii: 10.1007/s00134-018-5173.
    PubMed    


  94. HARIRI G, Joffre J, Deryckere S, Bige N, et al
    Albumin infusion improves endothelial function in septic shock patients: a pilot study.
    Intensive Care Med. 2018;44:669-671.
    PubMed    


    April 2018
  95. PERNER A, Cecconi M, Cronhjort M, Darmon M, et al
    Expert statement for the management of hypovolemia in sepsis.
    Intensive Care Med. 2018 Apr 25. pii: 10.1007/s00134-018-5177.
    PubMed     Abstract available


  96. LEVY MM, Evans LE, Rhodes A
    The Surviving Sepsis Campaign Bundle: 2018 update.
    Intensive Care Med. 2018 Apr 19. pii: 10.1007/s00134-018-5085.
    PubMed    


  97. ISHII J, Ohshimo S, Shime N, Lamontagne F, et al
    Target blood pressure for septic and vasodilatory shock: what is optimal?
    Intensive Care Med. 2018;44:548-549.
    PubMed    


  98. ARGENT AC, Chisti MJ, Ranjit S
    What's new in PICU in resource limited settings?
    Intensive Care Med. 2018;44:467-469.
    PubMed    


  99. COLOMBO J, Elzi L, Treglia G, Perren A, et al
    Light in the dark: (18)F-FDG PET/CT in Staphylococcus aureus bacteremia of unknown origin.
    Intensive Care Med. 2018;44:488-489.
    PubMed    


    March 2018
  100. RUSSELL JA, Spronk P, Walley KR
    Using multiple 'omics strategies for novel therapies in sepsis.
    Intensive Care Med. 2018 Mar 15. pii: 10.1007/s00134-018-5122.
    PubMed    


  101. SAITO H, Kilpatrick C, Pittet D
    The 2018 World Health Organization SAVE LIVES: Clean Your Hands Campaign targets sepsis in health care.
    Intensive Care Med. 2018 Mar 2. pii: 10.1007/s00134-018-5097.
    PubMed    


  102. WEISS SL, Deutschman CS
    Are septic children really just "septic little adults"?
    Intensive Care Med. 2018;44:392-394.
    PubMed    


  103. DE GROOTH HJ, Postema J, Loer SA, Parienti JJ, et al
    Unexplained mortality differences between septic shock trials: a systematic analysis of population characteristics and control-group mortality rates.
    Intensive Care Med. 2018;44:311-322.
    PubMed     Abstract available


  104. VINCENT JL, Lefrant JY, Kotfis K, Nanchal R, et al
    Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP).
    Intensive Care Med. 2018;44:337-344.
    PubMed     Abstract available


  105. WINISZEWSKI H, Labro G, Navellou JC, Piton G, et al
    Septic shock with round necrotic skin lesions.
    Intensive Care Med. 2018;44:374-375.
    PubMed    


    February 2018
  106. VIEILLARD-BARON A, Evrard B, Repesse X, Maizel J, et al
    Limited value of end-expiratory inferior vena cava diameter to predict fluid responsiveness impact of intra-abdominal pressure.
    Intensive Care Med. 2018;44:197-203.
    PubMed     Abstract available


  107. AU SY, Fong KM, Chan KLL, Sin KC, et al
    Diagnosing catheter associated blood-stream infection by transesophageal echocardiogram.
    Intensive Care Med. 2018;44:251.
    PubMed    


    January 2018
  108. SHANKAR-HARI M, Madsen MB, Turgeon AF
    Immunoglobulins and sepsis.
    Intensive Care Med. 2018 Jan 18. pii: 10.1007/s00134-018-5047.
    PubMed    


  109. FUJII T, Ganeko R, Kataoka Y, Furukawa TA, et al
    Correction to: Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.
    Intensive Care Med. 2018 Jan 16. pii: 10.1007/s00134-018-5055.
    PubMed     Abstract available


  110. LAMONTAGNE F, Day AG, Meade MO, Cook DJ, et al
    Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.
    Intensive Care Med. 2018;44:12-21.
    PubMed     Abstract available


  111. VAN DER KOOI T, Sax H, Pittet D, van Dissel J, et al
    Prevention of hospital infections by intervention and training (PROHIBIT): results of a pan-European cluster-randomized multicentre study to reduce central venous catheter-related bloodstream infections.
    Intensive Care Med. 2018;44:48-60.
    PubMed     Abstract available


  112. DEPRET F, Sitbon A, Soussi S, De Tymowski C, et al
    Intravenous iloprost to recruit the microcirculation in septic shock patients?
    Intensive Care Med. 2018;44:121-122.
    PubMed    


    December 2017
  113. SCHLAPBACH LJ, Straney L, Bellomo R, MacLaren G, et al
    Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit.
    Intensive Care Med. 2017 Dec 19. pii: 10.1007/s00134-017-5021.
    PubMed     Abstract available


  114. FUJII T, Ganeko R, Kataoka Y, Furukawa TA, et al
    Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.
    Intensive Care Med. 2017 Dec 4. pii: 10.1007/s00134-017-5004.
    PubMed     Abstract available


  115. MARX G
    Correction to: Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study.
    Intensive Care Med. 2017 Dec 1. pii: 10.1007/s00134-017-4980.
    PubMed     Abstract available


    November 2017
  116. VIEILLARD-BARON A, Boyd J
    Non-antiarrhythmic interventions in new onset and paroxysmal sepsis-related atrial fibrillation.
    Intensive Care Med. 2017 Nov 7. doi: 10.1007/s00134-017-4986.
    PubMed    


    October 2017
  117. NUNES C, Carvalho R, Ribeiro L, Lencastre L, et al
    When acrocyanosis in intensive care unit is not due to vasopressor support.
    Intensive Care Med. 2017 Oct 7. doi: 10.1007/s00134-017-4952.
    PubMed    


    September 2017
  118. ANNANE D, Pastores SM, Rochwerg B, Arlt W, et al
    Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.
    Intensive Care Med. 2017 Sep 21. doi: 10.1007/s00134-017-4919.
    PubMed     Abstract available


    August 2017
  119. TEBOUL JL, Duranteau J, Russell JA
    Intensive care medicine in 2050: vasopressors in sepsis.
    Intensive Care Med. 2017 Aug 31. doi: 10.1007/s00134-017-4909.
    PubMed    


  120. BAHLOUL M, Chtara K, Turki O, Khlaf Bouaziz N, et al
    Yarrowia lipolytica fungemia in patients with severe polytrauma requiring intensive care admission: analysis of 32 cases.
    Intensive Care Med. 2017 Aug 5. doi: 10.1007/s00134-017-4900.
    PubMed    


    July 2017
  121. AZOULAY E, Schellongowski P, Darmon M, Bauer PR, et al
    The Intensive Care Medicine research agenda on critically ill oncology and hematology patients.
    Intensive Care Med. 2017 Jul 19. doi: 10.1007/s00134-017-4884.
    PubMed     Abstract available


  122. GAUDRY S, Hajage D, Dreyfuss D, Joannidis M, et al
    Optimal timing of renal replacement therapy in patients with acute kidney injury in the context of sepsis : Discussion on "Sepsis: frontiers in supportive care, organisation and research".
    Intensive Care Med. 2017 Jul 12. doi: 10.1007/s00134-017-4856.
    PubMed    


    June 2017
  123. YAMAGA S, Shime N, Sonneville R, de Montmollin E, et al
    Risk factors for sepsis-associated encephalopathy.
    Intensive Care Med. 2017 Jun 29. doi: 10.1007/s00134-017-4875.
    PubMed    


  124. MER M, Schultz MJ, Adhikari NK
    Core elements of general supportive care for patients with sepsis and septic shock in resource-limited settings.
    Intensive Care Med. 2017 Jun 15. doi: 10.1007/s00134-017-4831.
    PubMed    


  125. YAMAGUCHI RS, Noritomi DT, Degaspare NV, Munoz GOC, et al
    Peripherally inserted central catheters are associated with lower risk of bloodstream infection compared with central venous catheters in paediatric intensive care patients: a propensity-adjusted analysis.
    Intensive Care Med. 2017 Jun 5. doi: 10.1007/s00134-017-4852.
    PubMed     Abstract available


    May 2017
  126. PERNER A, Gordon AC, Angus DC, Lamontagne F, et al
    The intensive care medicine research agenda on septic shock.
    Intensive Care Med. 2017 May 12. doi: 10.1007/s00134-017-4821.
    PubMed     Abstract available


  127. BLOOS F, Ruddel H, Thomas-Ruddel D, Schwarzkopf D, et al
    Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial.
    Intensive Care Med. 2017 May 2. doi: 10.1007/s00134-017-4782.
    PubMed     Abstract available


  128. SONNEVILLE R, de Montmollin E, Poujade J, Garrouste-Orgeas M, et al
    Potentially modifiable factors contributing to sepsis-associated encephalopathy.
    Intensive Care Med. 2017 May 2. doi: 10.1007/s00134-017-4807.
    PubMed     Abstract available


  129. LORTHOLARY O, Renaudat C, Sitbon K, Desnos-Ollivier M, et al
    The risk and clinical outcome of candidemia depending on underlying malignancy.
    Intensive Care Med. 2017;43:652-662.
    PubMed     Abstract available


  130. BOISSIER F, Razazi K, Seemann A, Bedet A, et al
    Left ventricular systolic dysfunction during septic shock: the role of loading conditions.
    Intensive Care Med. 2017;43:633-642.
    PubMed     Abstract available


    April 2017
  131. SCHLAPBACH LJ, Javouhey E, Jansen NJG
    Paediatric sepsis: old wine in new bottles?
    Intensive Care Med. 2017 Apr 22. doi: 10.1007/s00134-017-4800.
    PubMed    


  132. MARTIN-LOECHES I, Garnacho-Montero J, Nseir S
    Focus on infection and sepsis 2017.
    Intensive Care Med. 2017 Apr 4. doi: 10.1007/s00134-017-4787.
    PubMed    


  133. BASSETTI M, Peghin M, Carnelutti A, Righi E, et al
    Clinical characteristics and predictors of mortality in cirrhotic patients with candidemia and intra-abdominal candidiasis: a multicenter study.
    Intensive Care Med. 2017;43:509-518.
    PubMed     Abstract available


    March 2017
  134. BELLOMO R, Kellum JA, Ronco C, Wald R, et al
    Acute kidney injury in sepsis.
    Intensive Care Med. 2017 Mar 31. doi: 10.1007/s00134-017-4755.
    PubMed     Abstract available


  135. FORWARD E, Konecny P, Burston J, Adhikari S, et al
    Predictive validity of the qSOFA criteria for sepsis in non-ICU inpatients.
    Intensive Care Med. 2017 Mar 29. doi: 10.1007/s00134-017-4776.
    PubMed    


  136. SCHULTZ MJ, Dunser MW, Dondorp AM, Adhikari NK, et al
    Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future.
    Intensive Care Med. 2017 Mar 27. doi: 10.1007/s00134-017-4750.
    PubMed     Abstract available


  137. GENGA KR, Russell JA
    How much excess fluid impairs outcome of sepsis?
    Intensive Care Med. 2017 Mar 27. doi: 10.1007/s00134-017-4746.
    PubMed    


  138. SCULLY T, Clancy D, McLean AS, Orde S, et al
    Reversal in order of ventricular filling is associated with a positive fluid balance in sepsis.
    Intensive Care Med. 2017 Mar 23. doi: 10.1007/s00134-017-4769.
    PubMed    


  139. PICKKERS P, Payen D
    What's new in the extracorporeal treatment of sepsis?
    Intensive Care Med. 2017 Mar 17. doi: 10.1007/s00134-017-4738.
    PubMed    


  140. BASSETTI M, Garnacho-Montero J, Calandra T, Kullberg B, et al
    Intensive care medicine research agenda on invasive fungal infection in critically ill patients.
    Intensive Care Med. 2017 Mar 2. doi: 10.1007/s00134-017-4731.
    PubMed     Abstract available


    February 2017
  141. WONG HR
    Intensive care medicine in 2050: precision medicine.
    Intensive Care Med. 2017 Feb 24. doi: 10.1007/s00134-017-4727.
    PubMed    


  142. ESTEBAN E, Belda S, Garcia-Soler P, Rodriguez-Nunez A, et al
    A multifaceted educational intervention shortened time to antibiotic administration in children with severe sepsis and septic shock: ABISS Edusepsis pediatric study.
    Intensive Care Med. 2017 Feb 20. doi: 10.1007/s00134-017-4721.
    PubMed    


  143. SCHLAPBACH LJ, MacLaren G, Festa M, Alexander J, et al
    Prediction of pediatric sepsis mortality within 1 h of intensive care admission.
    Intensive Care Med. 2017 Feb 20. doi: 10.1007/s00134-017-4701.
    PubMed     Abstract available


  144. LEVI M, Schultz MJ
    What do sepsis-induced coagulation test result abnormalities mean to intensivists?
    Intensive Care Med. 2017 Feb 20. doi: 10.1007/s00134-017-4725.
    PubMed    


  145. MEZIANI F, Gando S, Vincent JL
    Should all patients with sepsis receive anticoagulation? Yes.
    Intensive Care Med. 2017 Feb 13. doi: 10.1007/s00134-016-4621.
    PubMed    


  146. ZHANG Z, Hong Y, Liu N, Chen Y, et al
    Association of do-not-resuscitate order and survival in patients with severe sepsis and/or septic shock.
    Intensive Care Med. 2017 Feb 2. doi: 10.1007/s00134-017-4690.
    PubMed    


  147. KERHUEL L, Valade S, Donay JL, Canet E, et al
    Angina, back pain and septic shock.
    Intensive Care Med. 2017;43:269-270.
    PubMed    


    January 2017
  148. MARLAIS M, Lyttle MD, Inwald D
    Erratum to: Ten concerns about blood pressure measurement and targets in paediatric sepsis.
    Intensive Care Med. 2017 Jan 31. doi: 10.1007/s00134-017-4692.
    PubMed    


  149. MARIK PE, Linde-Zwirble WT, Bittner EA, Sahatjian J, et al
    Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database.
    Intensive Care Med. 2017 Jan 27. doi: 10.1007/s00134-016-4675.
    PubMed     Abstract available


  150. PERNER A, Rhodes A, Venkatesh B, Angus DC, et al
    Sepsis: frontiers in supportive care, organisation and research.
    Intensive Care Med. 2017 Jan 27. doi: 10.1007/s00134-017-4677.
    PubMed     Abstract available


  151. RHODES A, Evans LE, Alhazzani W, Levy MM, et al
    Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
    Intensive Care Med. 2017 Jan 18. doi: 10.1007/s00134-017-4683.
    PubMed     Abstract available


  152. DELLINGER RP, Schorr CA, Levy MM
    A users' guide to the 2016 Surviving Sepsis Guidelines.
    Intensive Care Med. 2017 Jan 18. doi: 10.1007/s00134-017-4681.
    PubMed    


  153. LANKELMA JM, van Vught LA, Belzer C, Schultz MJ, et al
    Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study.
    Intensive Care Med. 2017;43:59-68.
    PubMed     Abstract available


    December 2016
  154. AUBRY A, Allouch P, Squara P, Vieillard-Baron A, et al
    A "UFO" in the right pulmonary artery after cardiac surgery.
    Intensive Care Med. 2016 Dec 24. doi: 10.1007/s00134-016-4644.
    PubMed    


  155. MARLAIS M, Lyttle MD, Inwald D
    Ten concerns about blood pressure measurement and targets in paediatric sepsis.
    Intensive Care Med. 2016.
    PubMed    


    November 2016
  156. IBA T, Thachil J
    Is protein C zymogen really ineffective for ALL cases of sepsis including septic DIC?
    Intensive Care Med. 2016.
    PubMed    


  157. SPRUNG CL, Schein RM, Balk RA
    The new sepsis consensus definitions: the good, the bad and the ugly.
    Intensive Care Med. 2016.
    PubMed    


  158. SINGER M
    The new sepsis consensus definitions (Sepsis-3): the good, the not-so-bad, and the actually-quite-pretty.
    Intensive Care Med. 2016.
    PubMed    


    October 2016
  159. TIMSIT JF, Perner A
    Sepsis: find me, manage me, and stop me!
    Intensive Care Med. 2016.
    PubMed    


  160. KRUGER PS, Terblanche M
    Statins in patients with sepsis and ARDS: is it over? No.
    Intensive Care Med. 2016.
    PubMed    


  161. MCAULEY D, Charles PE, Papazian L
    Statins in patients with sepsis and ARDS: is it over? We are not sure.
    Intensive Care Med. 2016.
    PubMed    


  162. ALHAZZANI W, Truwit J
    Statins in patients with sepsis and ARDS: is it over? Yes.
    Intensive Care Med. 2016.
    PubMed    


  163. THWAITES CL, Lundeg G, Dondorp AM
    Infection management in patients with sepsis and septic shock in resource-limited settings.
    Intensive Care Med. 2016.
    PubMed    


  164. ROSHDY A
    Infection management in patients with sepsis and septic shock in resource-limited settings: focus on appropriate antimicrobial.
    Intensive Care Med. 2016.
    PubMed    


  165. SILVERSIDES JA, Major E, Ferguson AJ, Mann EE, et al
    Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical illness: a systematic review and meta-analysis.
    Intensive Care Med. 2016.
    PubMed     Abstract available


  166. MORIN L, Ray S, Wilson C, Remy S, et al
    Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition.
    Intensive Care Med. 2016.
    PubMed     Abstract available


  167. VINCENT JL, Martin-Loeches I, Annane D
    What patient data should be collected in this randomized controlled trial in sepsis?
    Intensive Care Med. 2016.
    PubMed    


  168. PERNER A, Gordon AC, De Backer D, Dimopoulos G, et al
    Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy.
    Intensive Care Med. 2016.
    PubMed     Abstract available


    September 2016
  169. DELANEY A, Machado F
    In sepsis, everything old is new again.
    Intensive Care Med. 2016.
    PubMed    



  170. Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study.
    Intensive Care Med. 2016.
    PubMed     Abstract available


  171. JENSEN JU, Bouadma L
    Why biomarkers failed in sepsis.
    Intensive Care Med. 2016.
    PubMed    


  172. BLOCH A, Berger D, Takala J
    Understanding circulatory failure in sepsis.
    Intensive Care Med. 2016.
    PubMed    


    April 2016
  173. ALLINGSTRUP M, Wetterslev J, Ravn FB, Moller AM, et al
    Antithrombin III for critically ill patients: a systematic review with meta-analysis and trial sequential analysis.
    Intensive Care Med. 2016;42:505-20.
    PubMed     Abstract available


  174. BAILLY S, Pirracchio R, Timsit JF
    What's new in the quantification of causal effects from longitudinal cohort studies: a brief introduction to marginal structural models for intensivists.
    Intensive Care Med. 2016;42:576-9.
    PubMed    


    March 2016
  175. DE MOURA EB, Amorim FF, da Cruz Santana AN, Kanhouche G, et al
    Skin mottling score as a predictor of 28-day mortality in patients with septic shock.
    Intensive Care Med. 2016;42:479-80.
    PubMed    


  176. DEPUYDT PO, Kress JP, Salluh JI
    The ten "diseases" that are not true diseases.
    Intensive Care Med. 2016;42:411-4.
    PubMed    


    February 2016
  177. CLARK E, Kumar A, Langote A, Lapinsky S, et al
    Septic shock in chronic dialysis patients: clinical characteristics, antimicrobial therapy and mortality.
    Intensive Care Med. 2016;42:222-32.
    PubMed     Abstract available


  178. FALCONE M, Russo A, Farcomeni A, Pieralli F, et al
    Septic shock from community-onset pneumonia: is there a role for aspirin plus macrolides combination?
    Intensive Care Med. 2016;42:301-2.
    PubMed    


  179. OSPINA-TASCON GA, Umana M, Bermudez WF, Bautista-Rincon DF, et al
    Can venous-to-arterial carbon dioxide differences reflect microcirculatory alterations in patients with septic shock?
    Intensive Care Med. 2016;42:211-21.
    PubMed     Abstract available


  180. HAAS SA, Lange T, Saugel B, Petzoldt M, et al
    Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients.
    Intensive Care Med. 2016;42:202-10.
    PubMed     Abstract available


    January 2016
  181. HSU CW, Lin CS, Chen SJ, Lin SH, et al
    Risk of type 2 diabetes mellitus in patients with acute critical illness: a population-based cohort study.
    Intensive Care Med. 2016;42:38-45.
    PubMed     Abstract available


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