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  Rheumatoid Arthritis

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Articles published in J Immunol

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    July 2021
  1. CARVAJAL ALEGRIA G, Cornec D, Saraux A, Devauchelle-Pensec V, et al
    Abatacept Promotes Regulatory B Cell Functions, Enhancing Their Ability to Reduce the Th1 Response in Rheumatoid Arthritis Patients through the Production of IL-10 and TGF-beta.
    J Immunol. 2021 Jul 9. pii: jimmunol.2000455. doi: 10.4049/jimmunol.2000455.
    PubMed     Abstract available

    June 2021
  2. LEE YJ, Park EH, Park JW, Jung KC, et al
    Proinflammatory Features of Stem Cell-like Memory T Cells from Human Patients with Rheumatoid Arthritis.
    J Immunol. 2021 Jun 23. pii: jimmunol.2000814. doi: 10.4049/jimmunol.2000814.
    PubMed     Abstract available

    April 2021
  3. SAKURAGI T, Yamada H, Haraguchi A, Kai K, et al
    Autoreactivity of Peripheral Helper T Cells in the Joints of Rheumatoid Arthritis.
    J Immunol. 2021 Apr 12. pii: jimmunol.2000783. doi: 10.4049/jimmunol.2000783.
    PubMed     Abstract available

    January 2021
  4. BATES NA, Li A, Fan T, Cutcliffe MP, et al
    Gut Commensal Segmented Filamentous Bacteria Fine-Tune T Follicular Regulatory Cells to Modify the Severity of Systemic Autoimmune Arthritis.
    J Immunol. 2021 Jan 18. pii: jimmunol.2000663. doi: 10.4049/jimmunol.2000663.
    PubMed     Abstract available

    December 2020
  5. KRISHNA V, Yin X, Song Q, Walsh A, et al
    Integration of the Transcriptome and Genome-Wide Landscape of BRD2 and BRD4 Binding Motifs Identifies Key Superenhancer Genes and Reveals the Mechanism of Bet Inhibitor Action in Rheumatoid Arthritis Synovial Fibroblasts.
    J Immunol. 2020 Dec 7. pii: jimmunol.2000286. doi: 10.4049/jimmunol.2000286.
    PubMed     Abstract available

  6. WANG X, Tu J, Jiang J, Zhang Q, et al
    Angiotensin II Type 2 Receptor Modulates Synovial Macrophage Polarization by Inhibiting GRK2 Membrane Translocation in a Rat Model of Collagen-Induced Arthritis.
    J Immunol. 2020;205:3141-3153.
    PubMed     Abstract available

    November 2020
  7. KORN MA, Schmitt H, Angermuller S, Chambers D, et al
    Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis.
    J Immunol. 2020;205:2595-2605.
    PubMed     Abstract available

  8. WEHRLI M, Schneider C, Cortinas-Elizondo F, Verschoor D, et al
    IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators.
    J Immunol. 2020;205:2640-2648.
    PubMed     Abstract available

  9. SUGIURA T, Kamino H, Nariai Y, Murakawa Y, et al
    Screening of a Panel of Low Molecular Weight Compounds That Inhibit Synovial Fibroblast Invasion in Rheumatoid Arthritis.
    J Immunol. 2020 Nov 11. pii: jimmunol.1901429. doi: 10.4049/jimmunol.1901429.
    PubMed     Abstract available

    September 2020
  10. WANG X, Gessier F, Perozzo R, Stojkov D, et al
    RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-alpha.
    J Immunol. 2020;205:1653-1663.
    PubMed     Abstract available

    August 2020
  11. LI M, Yang C, Wang Y, Song W, et al
    The Expression of P2X7 Receptor on Th1, Th17, and Regulatory T Cells in Patients with Systemic Lupus Erythematosus or Rheumatoid Arthritis and Its Correlations with Active Disease.
    J Immunol. 2020 Aug 31. pii: jimmunol.2000222. doi: 10.4049/jimmunol.2000222.
    PubMed     Abstract available

  12. VAN DRONGELEN V, Ali WH, Holoshitz J
    Uncovering a Shared Epitope-Activated Protein Citrullination Pathway.
    J Immunol. 2020;205:579-586.
    PubMed     Abstract available

    July 2020
  13. YEUNG L, Anderson JML, Wee JL, Demaria MC, et al
    Leukocyte Tetraspanin CD53 Restrains alpha3 Integrin Mobilization and Facilitates Cytoskeletal Remodeling and Transmigration in Mice.
    J Immunol. 2020;205:521-532.
    PubMed     Abstract available

  14. XU J, Jiang C, Wang X, Geng M, et al
    Upregulated PKM2 in Macrophages Exacerbates Experimental Arthritis via STAT1 Signaling.
    J Immunol. 2020;205:181-192.
    PubMed     Abstract available

    June 2020
  15. VANARSA K, Henderson J, Soomro S, Qin L, et al
    Upregulation of Proinflammatory Bradykinin Peptides in Systemic Lupus Erythematosus and Rheumatoid Arthritis.
    J Immunol. 2020 Jun 15. pii: jimmunol.1801167. doi: 10.4049/jimmunol.1801167.
    PubMed     Abstract available

    April 2020
  16. VOGT LM, Kwasniewicz E, Talens S, Scavenius C, et al
    Apolipoprotein E Triggers Complement Activation in Joint Synovial Fluid of Rheumatoid Arthritis Patients by Binding C1q.
    J Immunol. 2020 Apr 6. pii: jimmunol.1900372. doi: 10.4049/jimmunol.1900372.
    PubMed     Abstract available

    March 2020
  17. CORSIERO E, Carlotti E, Jagemann L, Perretti M, et al
    H and L Chain Affinity Maturation and/or Fab N-Glycosylation Influence Immunoreactivity toward Neutrophil Extracellular Trap Antigens in Rheumatoid Arthritis Synovial B Cell Clones.
    J Immunol. 2020 Mar 27. pii: jimmunol.1901457. doi: 10.4049/jimmunol.1901457.
    PubMed     Abstract available

    January 2020
  18. DURKIN A, Vu HY, Lee H
    The VR23 Antitumor Compound Also Shows Strong Anti-Inflammatory Effects in a Human Rheumatoid Arthritis Cell Model and Acute Lung Inflammation in Mice.
    J Immunol. 2020 Jan 8. pii: jimmunol.1900531. doi: 10.4049/jimmunol.1900531.
    PubMed     Abstract available

    September 2019
  19. PAOLETTI A, Rohmer J, Ly B, Pascaud J, et al
    Monocyte/Macrophage Abnormalities Specific to Rheumatoid Arthritis Are Linked to miR-155 and Are Differentially Modulated by Different TNF Inhibitors.
    J Immunol. 2019 Sep 4. pii: jimmunol.1900386. doi: 10.4049/jimmunol.1900386.
    PubMed     Abstract available

    July 2019
  20. DU Y, Lu C, Morgan RL, Stinson WA, et al
    Angiogenic and Arthritogenic Properties of the Soluble Form of CD13.
    J Immunol. 2019;203:360-369.
    PubMed     Abstract available

    June 2019
  21. KRISHNAMURTHY A, Ytterberg AJ, Sun M, Sakuraba K, et al
    Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts.
    J Immunol. 2019;202:3143-3150.
    PubMed     Abstract available

    April 2019
  22. HASELMAYER P, Camps M, Liu-Bujalski L, Nguyen N, et al
    Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models.
    J Immunol. 2019 Apr 15. pii: jimmunol.1800583. doi: 10.4049/jimmunol.1800583.
    PubMed     Abstract available

  23. SHEN F, Verma AH, Volk A, Jones B, et al
    Combined Blockade of TNF-alpha and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice.
    J Immunol. 2019;202:2017-2026.
    PubMed     Abstract available

    March 2019
  24. TIAN J, Rui K, Hong Y, Wang X, et al
    Increased GITRL Impairs the Function of Myeloid-Derived Suppressor Cells and Exacerbates Primary Sjogren Syndrome.
    J Immunol. 2019;202:1693-1703.
    PubMed     Abstract available

    January 2019
  25. DORRIS ER, Tazzyman SJ, Moylett J, Ramamoorthi N, et al
    The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation.
    J Immunol. 2019 Jan 18. pii: jimmunol.1801155. doi: 10.4049/jimmunol.1801155.
    PubMed     Abstract available

  26. NIKITIN PA, Rose EL, Byun TS, Parry GC, et al
    C1s Inhibition by BIVV009 (Sutimlimab) Prevents Complement-Enhanced Activation of Autoimmune Human B Cells In Vitro.
    J Immunol. 2019 Jan 11. pii: jimmunol.1800998. doi: 10.4049/jimmunol.1800998.
    PubMed     Abstract available

    December 2018
  27. CLANCY RM, Halushka M, Rasmussen SE, Lhakhang T, et al
    Siglec-1 Macrophages and the Contribution of IFN to the Development of Autoimmune Congenital Heart Block.
    J Immunol. 2018 Dec 5. pii: jimmunol.1800357. doi: 10.4049/jimmunol.1800357.
    PubMed     Abstract available

    September 2018
  28. CHEN Z, Wang H, Xia Y, Yan F, et al
    Therapeutic Potential of Mesenchymal Cell-Derived miRNA-150-5p-Expressing Exosomes in Rheumatoid Arthritis Mediated by the Modulation of MMP14 and VEGF.
    J Immunol. 2018 Sep 17. pii: jimmunol.1800304. doi: 10.4049/jimmunol.1800304.
    PubMed     Abstract available

    June 2018
  29. MUSTERS A, Klarenbeek PL, Doorenspleet ME, Balzaretti G, et al
    In Rheumatoid Arthritis, Synovitis at Different Inflammatory Sites Is Dominated by Shared but Patient-Specific T Cell Clones.
    J Immunol. 2018 Jun 11. pii: jimmunol.1800421. doi: 10.4049/jimmunol.1800421.
    PubMed     Abstract available

    May 2018
  30. PANNETON V, Bagherzadeh Yazdchi S, Witalis M, Chang J, et al
    ICOS Signaling Controls Induction and Maintenance of Collagen-Induced Arthritis.
    J Immunol. 2018;200:3067-3076.
    PubMed     Abstract available

    April 2018
  31. ZHONG Q, Gong FY, Gong Z, Hua SH, et al
    IgG Immunocomplexes Sensitize Human Monocytes for Inflammatory Hyperactivity via Transcriptomic and Epigenetic Reprogramming in Rheumatoid Arthritis.
    J Immunol. 2018 Apr 30. pii: jimmunol.1701756. doi: 10.4049/jimmunol.1701756.
    PubMed     Abstract available

    March 2018
  32. MCNAUGHTON EF, Eustace AD, King S, Sessions RB, et al
    Novel Anti-Inflammatory Peptides Based on Chemokine-Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis.
    J Immunol. 2018 Mar 23. pii: jimmunol.1701187. doi: 10.4049/jimmunol.1701187.
    PubMed     Abstract available

  33. STOPFORTH RJ, Oldham RJ, Tutt AL, Duriez P, et al
    Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcgammaRIIB.
    J Immunol. 2018;200:1937-1950.
    PubMed     Abstract available

    February 2018
  34. ALMHOLT K, Hebsgaard JB, Nansen A, Andersson C, et al
    Antibody-Mediated Neutralization of uPA Proteolytic Function Reduces Disease Progression in Mouse Arthritis Models.
    J Immunol. 2018;200:957-965.
    PubMed     Abstract available

    January 2018
  35. HUANG QQ, Birkett R, Doyle R, Shi B, et al
    The Role of Macrophages in the Response to TNF Inhibition in Experimental Arthritis.
    J Immunol. 2018;200:130-138.
    PubMed     Abstract available

    December 2017
  36. TANAKA Y, Sotome T, Inoue A, Mukozu T, et al
    SATB1 Conditional Knockout Results in Sjogren's Syndrome in Mice.
    J Immunol. 2017;199:4016-4022.
    PubMed     Abstract available

    October 2017
  37. EMORI T, Hirose J, Ise K, Yomoda JI, et al
    Constitutive Activation of Integrin alpha9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis.
    J Immunol. 2017 Oct 16. pii: ji1700941. doi: 10.4049/jimmunol.1700941.
    PubMed     Abstract available

  38. KIM S, Easterling ER, Price LC, Smith SL, et al
    The Role of Leukocyte-Associated Ig-like Receptor-1 in Suppressing Collagen-Induced Arthritis.
    J Immunol. 2017;199:2692-2700.
    PubMed     Abstract available

  39. MATSUDA S, Hammaker D, Topolewski K, Briegel KJ, et al
    Regulation of the Cell Cycle and Inflammatory Arthritis by the Transcription Cofactor LBH Gene.
    J Immunol. 2017;199:2316-2322.
    PubMed     Abstract available

    September 2017
  40. BANDA NK, Acharya S, Scheinman RI, Mehta G, et al
    Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.
    J Immunol. 2017;199:1835-1845.
    PubMed     Abstract available

    July 2017
  41. LIU S, Hasegawa H, Takemasa E, Suzuki Y, et al
    Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft Models.
    J Immunol. 2017 Jul 17. pii: ji1700192. doi: 10.4049/jimmunol.1700192.
    PubMed     Abstract available

    June 2017
  42. VOGT LM, Talens S, Kwasniewicz E, Scavenius C, et al
    Activation of Complement by Pigment Epithelium-Derived Factor in Rheumatoid Arthritis.
    J Immunol. 2017 Jun 21. pii: ji1700018. doi: 10.4049/jimmunol.1700018.
    PubMed     Abstract available

  43. LEFEVRE S, Schwarz M, Meier FMP, Zimmermann-Geller B, et al
    Disease-Specific Effects of Matrix and Growth Factors on Adhesion and Migration of Rheumatoid Synovial Fibroblasts.
    J Immunol. 2017;198:4588-4595.
    PubMed     Abstract available

    May 2017
  44. LEE MC, McCubbin JA, Christensen AD, Poole DP, et al
    G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease.
    J Immunol. 2017;198:3565-3575.
    PubMed     Abstract available

  45. BINDER N, Miller C, Yoshida M, Inoue K, et al
    Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.
    J Immunol. 2017;198:3436-3447.
    PubMed     Abstract available

    April 2017
  46. GUO Y, Walsh AM, Fearon U, Smith MD, et al
    CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression.
    J Immunol. 2017 Apr 28. pii: 1601988. doi: 10.4049/jimmunol.1601988.
    PubMed     Abstract available

  47. TYKOCINSKI LO, Lauffer AM, Bohnen A, Kaul NC, et al
    Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.
    J Immunol. 2017;198:3109-3117.
    PubMed     Abstract available

    March 2017
  48. BASDEO SA, Cluxton D, Sulaimani J, Moran B, et al
    Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells.
    J Immunol. 2017;198:2249-2259.
    PubMed     Abstract available

    January 2017
  49. NASKAR D, Teng F, Felix KM, Bradley CP, et al
    Synthetic Retinoid AM80 Ameliorates Lung and Arthritic Autoimmune Responses by Inhibiting T Follicular Helper and Th17 Cell Responses.
    J Immunol. 2017 Jan 27. pii: 1601776. doi: 10.4049/jimmunol.1601776.
    PubMed     Abstract available

  50. BOUCHAREYCHAS L, Grossinger EM, Kang M, Qiu H, et al
    Critical Role of LTB4/BLT1 in IL-23-Induced Synovial Inflammation and Osteoclastogenesis via NF-kappaB.
    J Immunol. 2017;198:452-460.
    PubMed     Abstract available

  51. FALKENBURG WJ, van Schaardenburg D, Ooijevaar-de Heer P, Tsang-A-Sjoe MW, et al
    Anti-Hinge Antibodies Recognize IgG Subclass- and Protease-Restricted Neoepitopes.
    J Immunol. 2017;198:82-93.
    PubMed     Abstract available

    June 2016
  52. SOOD S, Brownlie RJ, Garcia C, Cowan G, et al
    Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice.
    J Immunol. 2016 Jun 10. pii: 1502656.
    PubMed     Abstract available

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