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COVID-19: Daily Top 10 Papers


  Pulmonary Hypertension

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Articles published in PLoS One

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Single Articles


    January 2021
  1. FINGROVA Z, Ambroz D, Jansa P, Kuchar J, et al
    The prevalence and clinical outcome of supraventricular tachycardia in different etiologies of pulmonary hypertension.
    PLoS One. 2021;16:e0245752.
    PubMed     Abstract available


  2. RAJARATNAM A, Rehman S, Sharma P, Singh VK, et al
    Right ventricular load and contractility in HIV-associated pulmonary hypertension.
    PLoS One. 2021;16:e0243274.
    PubMed     Abstract available


  3. IBE T, Wada H, Sakakura K, Ugata Y, et al
    Combined pre- and post-capillary pulmonary hypertension: The clinical implications for patients with heart failure.
    PLoS One. 2021;16:e0247987.
    PubMed     Abstract available


  4. HONIGBERG MC, Patel AP, Lahm T, Wood MJ, et al
    Association of premature menopause with incident pulmonary hypertension: A cohort study.
    PLoS One. 2021;16:e0247398.
    PubMed     Abstract available


  5. TAWA M, Nagata R, Sumi Y, Nakagawa K, et al
    Preventive effects of nitrate-rich beetroot juice supplementation on monocrotaline-induced pulmonary hypertension in rats.
    PLoS One. 2021;16:e0249816.
    PubMed     Abstract available


  6. MOHER ALSADY T, Kaireit TF, Behrendt L, Winther HB, et al
    Comparison of dual-energy computer tomography and dynamic contrast-enhanced MRI for evaluating lung perfusion defects in chronic thromboembolic pulmonary hypertension.
    PLoS One. 2021;16:e0251740.
    PubMed     Abstract available


  7. FUJII S, Nagayoshi S, Ogawa K, Muto M, et al
    A pilot cohort study assessing the feasibility of complete revascularization with balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension.
    PLoS One. 2021;16:e0254770.
    PubMed     Abstract available


  8. MIURA K, Katsumata Y, Kawakami T, Ikura H, et al
    Exercise tolerance and quality of life in hemodynamically partially improved patients with chronic thromboembolic pulmonary hypertension treated with balloon pulmonary angioplasty.
    PLoS One. 2021;16:e0255180.
    PubMed     Abstract available


  9. RIENGVIRODKIJ N, Roytrakul S, Jaresitthikunchai J, Phaonakrop N, et al
    Peptide barcodes in dogs affected by mitral valve disease with and without pulmonary hypertension using MALDI-TOF MS and LC-MS/MS.
    PLoS One. 2021;16:e0255611.
    PubMed     Abstract available


  10. BUTT S, Jeppesen JL, Iversen LV, Fenger M, et al
    Association of soluble urokinase plasminogen activator receptor levels with fibrotic and vascular manifestations in systemic sclerosis.
    PLoS One. 2021;16:e0247256.
    PubMed     Abstract available


    January 2020
  11. RINASTITI P, Ikeda K, Rahardini EP, Miyagawa K, et al
    Loss of family with sequence similarity 13, member A exacerbates pulmonary hypertension through accelerating endothelial-to-mesenchymal transition.
    PLoS One. 2020;15:e0226049.
    PubMed     Abstract available


  12. ZOUK AN, Gulati S, Xing D, Wille KM, et al
    Pulmonary artery enlargement is associated with pulmonary hypertension and decreased survival in severe cystic fibrosis: A cohort study.
    PLoS One. 2020;15:e0229173.
    PubMed     Abstract available


  13. SARA JDS, Maor E, Borlaug B, Lewis BR, et al
    Non-invasive vocal biomarker is associated with pulmonary hypertension.
    PLoS One. 2020;15:e0231441.
    PubMed     Abstract available


  14. CONNOLLY M, Garfield BE, Crosby A, Morrell NW, et al
    miR-1-5p targets TGF-betaR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.
    PLoS One. 2020;15:e0229409.
    PubMed     Abstract available


  15. KAISER R, Liu D, Arias-Loza P, Hu K, et al
    Right ventricular pressure overload directly affects left ventricular torsion mechanics in patients with precapillary pulmonary hypertension.
    PLoS One. 2020;15:e0232544.
    PubMed     Abstract available


  16. CASTRO MA, Piloto B, Dos Santos Fernandes CJC, Jardim C, et al
    Use of medical therapies before pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension patients with severe hemodynamic impairment.
    PLoS One. 2020;15:e0233063.
    PubMed     Abstract available


  17. SCHNEIDER M, Ran H, Pistritto AM, Gerges C, et al
    Pulmonary artery to ascending aorta ratio by echocardiography: A strong predictor for presence and severity of pulmonary hypertension.
    PLoS One. 2020;15:e0235716.
    PubMed     Abstract available


  18. NAKATSUKA Y, Chen-Yoshikawa T, Kinoshita H, Aoyama A, et al
    Nocturnal hypercapnia with daytime normocapnia in patients with advanced pulmonary arterial hypertension awaiting lung transplantation.
    PLoS One. 2020;15:e0227775.
    PubMed     Abstract available


  19. HILDE JM, Hisdal J, Skjorten I, Hansteen V, et al
    Left ventricular dysfunction in COPD without pulmonary hypertension.
    PLoS One. 2020;15:e0235075.
    PubMed     Abstract available


  20. ZOU XL, Ren Y, Feng DY, He XQ, et al
    A promising approach for screening pulmonary hypertension based on frontal chest radiographs using deep learning: A retrospective study.
    PLoS One. 2020;15:e0236378.
    PubMed     Abstract available


  21. HERNANDEZ-GONZALEZ I, Tenorio J, Palomino-Doza J, Martinez Menaca A, et al
    Clinical heterogeneity of Pulmonary Arterial Hypertension associated with variants in TBX4.
    PLoS One. 2020;15:e0232216.
    PubMed     Abstract available


  22. BOON GJAM, Rein NV, Bogaard HJ, Ende-Verhaar YM, et al
    Quality of initial anticoagulant treatment and risk of CTEPH after acute pulmonary embolism.
    PLoS One. 2020;15:e0232354.
    PubMed     Abstract available


  23. RIEG AD, Suleiman S, Bunting NA, Verjans E, et al
    Levosimendan reduces segmental pulmonary vascular resistance in isolated perfused rat lungs and relaxes human pulmonary vessels.
    PLoS One. 2020;15:e0233176.
    PubMed     Abstract available


  24. ZHANG H, Huang W, Liu H, Zheng Y, et al
    Mechanical stretching of pulmonary vein stimulates matrix metalloproteinase-9 and transforming growth factor-beta1 through stretch-activated channel/MAPK pathways in pulmonary hypertension due to left heart disease model rats.
    PLoS One. 2020;15:e0235824.
    PubMed     Abstract available


  25. SASAKI K, Yamamoto S, Mutoh T
    Noninvasive assessment of fluid responsiveness for emergency abdominal surgery in dogs with pulmonary hypertension: Insights into high-risk companion animal anesthesia.
    PLoS One. 2020;15:e0241234.
    PubMed     Abstract available


  26. JANG AY, Kim BG, Kwon S, Seo J, et al
    Prevalence and clinical features of bone morphogenetic protein receptor type 2 mutation in Korean idiopathic pulmonary arterial hypertension patients: The PILGRIM explorative cohort.
    PLoS One. 2020;15:e0238698.
    PubMed     Abstract available


  27. CZERNER CP, Schoenfeld C, Cebotari S, Renne J, et al
    Perioperative CTEPH patient monitoring with 2D phase-contrast MRI reflects clinical, cardiac and pulmonary perfusion changes after pulmonary endarterectomy.
    PLoS One. 2020;15:e0238171.
    PubMed     Abstract available


  28. VALENTE C, Guglielmini C, Domenech O, Contiero B, et al
    Symmetric dimethylarginine in dogs with myxomatous mitral valve disease at various stages of disease severity.
    PLoS One. 2020;15:e0238440.
    PubMed     Abstract available


  29. SALIBE-FILHO W, Araujo TLS, G Melo E, B C T Coimbra L, et al
    Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension.
    PLoS One. 2020;15:e0242960.
    PubMed     Abstract available


  30. CASTELLVI I, Simeon CP, Sarmiento M, Casademont J, et al
    Effect of bosentan in pulmonary hypertension development in systemic sclerosis patients with digital ulcers.
    PLoS One. 2020;15:e0243651.
    PubMed     Abstract available


  31. MOHAMMAD AM, Dawad MM, Kashmoola MA, Al-Allawi N, et al
    Doppler-defined pulmonary hypertension in beta-thalassemia major in Kurdistan, Iraq.
    PLoS One. 2020;15:e0243648.
    PubMed     Abstract available


  32. HONDA Y, Kosugi K, Fuchikami C, Kuramoto K, et al
    The selective PGI2 receptor agonist selexipag ameliorates Sugen 5416/hypoxia-induced pulmonary arterial hypertension in rats.
    PLoS One. 2020;15:e0240692.
    PubMed     Abstract available


  33. SAHAY S, Tonelli AR, Selej M, Watson Z, et al
    Risk assessment in patients with functional class II pulmonary arterial hypertension: Comparison of physician gestalt with ESC/ERS and the REVEAL 2.0 risk score.
    PLoS One. 2020;15:e0241504.
    PubMed     Abstract available


    January 2019
  34. NAITO A, Hiwasa T, Tanabe N, Sanada TJ, et al
    Elevated levels of autoantibodies against EXD2 and PHAX in the sera of patients with chronic thromboembolic pulmonary hypertension.
    PLoS One. 2019;14:e0211377.
    PubMed     Abstract available


  35. POWER AS, Norman R, Jones TLM, Hickey AJ, et al
    Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment.
    PLoS One. 2019;14:e0214740.
    PubMed     Abstract available


  36. COTTIN V, Avot D, Levy-Bachelot L, Baxter CA, et al
    Identifying chronic thromboembolic pulmonary hypertension through the French national hospital discharge database.
    PLoS One. 2019;14:e0214649.
    PubMed     Abstract available


  37. DAVIS EM, Baust JJ, O'Donnell BJ, Shah FA, et al
    Correction: A phenotype of increased sleepiness in a mouse model of pulmonary hypertension and right ventricular hypertrophy.
    PLoS One. 2019;14:e0218401.
    PubMed     Abstract available


  38. PISCHKE SE, Hestenes S, Johansen HT, Fure H, et al
    Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model.
    PLoS One. 2019;14:e0218624.
    PubMed     Abstract available


  39. HAN BG, Kim J, Jung IY, Son JW, et al
    Relationship between volume status and possibility of pulmonary hypertension in dialysis naive CKD5 patients.
    PLoS One. 2019;14:e0221970.
    PubMed     Abstract available


  40. KOMPOTIATIS P, Wiley BM, Jentzer JC, Kashani KB, et al
    Echocardiographic parameters of patients in the intensive care unit undergoing continuous renal replacement therapy.
    PLoS One. 2019;14:e0209994.
    PubMed     Abstract available


  41. SIEREN MM, Berlin C, Oechtering TH, Hunold P, et al
    Comparison of 4D Flow MRI to 2D Flow MRI in the pulmonary arteries in healthy volunteers and patients with pulmonary hypertension.
    PLoS One. 2019;14:e0224121.
    PubMed     Abstract available


  42. LEHA A, Hellenkamp K, Unsold B, Mushemi-Blake S, et al
    A machine learning approach for the prediction of pulmonary hypertension.
    PLoS One. 2019;14:e0224453.
    PubMed     Abstract available


  43. WERTHEIM BM, Lin YD, Zhang YY, Samokhin AO, et al
    Isolating pulmonary microvascular endothelial cells ex vivo: Implications for pulmonary arterial hypertension, and a caution on the use of commercial biomaterials.
    PLoS One. 2019;14:e0211909.
    PubMed     Abstract available


  44. CHIDA-NAGAI A, Shintani M, Sato H, Nakayama T, et al
    Role of BRCA1-associated protein (BRAP) variant in childhood pulmonary arterial hypertension.
    PLoS One. 2019;14:e0211450.
    PubMed     Abstract available


  45. AL-ZAHRANI K, Licknack T, Watson DL, Anthony NB, et al
    Further investigation of mitochondrial biogenesis and gene expression of key regulators in ascites- susceptible and ascites- resistant broiler research lines.
    PLoS One. 2019;14:e0205480.
    PubMed     Abstract available


  46. WAKASUGI T, Shimizu I, Yoshida Y, Hayashi Y, et al
    Role of smooth muscle cell p53 in pulmonary arterial hypertension.
    PLoS One. 2019;14:e0212889.
    PubMed     Abstract available


  47. HAYABUCHI Y, Homma Y, Kagami S
    Optical coherence tomography for observing development of pulmonary arterial vasa vasorum after bidirectional cavopulmonary connection in children.
    PLoS One. 2019;14:e0215146.
    PubMed     Abstract available


  48. CHUNCHARUNEE S, Teawtrakul N, Siritanaratkul N, Chueamuangphan N, et al
    Review of disease-related complications and management in adult patients with thalassemia: A multi-center study in Thailand.
    PLoS One. 2019;14:e0214148.
    PubMed     Abstract available


  49. BHAGWANI AR, Hultman S, Farkas D, Moncayo R, et al
    Endothelial cells are a source of Nestin expression in Pulmonary Arterial Hypertension.
    PLoS One. 2019;14:e0213890.
    PubMed     Abstract available


  50. SHAH NB, Mitchell RE, Proctor ST, Choi L, et al
    High rates of medication adherence in patients with pulmonary arterial hypertension: An integrated specialty pharmacy approach.
    PLoS One. 2019;14:e0217798.
    PubMed     Abstract available


  51. TSUTSUMI T, Nagaoka T, Yoshida T, Wang L, et al
    Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation.
    PLoS One. 2019;14:e0214697.
    PubMed     Abstract available


  52. WILSON JL, Wang L, Zhang Z, Hill NS, et al
    Participation of PLK1 and FOXM1 in the hyperplastic proliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension.
    PLoS One. 2019;14:e0221728.
    PubMed     Abstract available


  53. SEKI M, Furukawa N, Koitabashi N, Obokata M, et al
    Periostin-expressing cell-specific transforming growth factor-beta inhibition in pulmonary artery prevents pulmonary arterial hypertension.
    PLoS One. 2019;14:e0220795.
    PubMed     Abstract available


  54. BRUNS DR, Tatman PD, Kalkur RS, Brown RD, et al
    The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation.
    PLoS One. 2019;14:e0220573.
    PubMed     Abstract available


  55. NGUYEN QL, Wang Y, Helbling N, Simon MA, et al
    Alterations in platelet bioenergetics in Group 2 PH-HFpEF patients.
    PLoS One. 2019;14:e0220490.
    PubMed     Abstract available


  56. BERGOT E, De Leotoing L, Bendjenana H, Tournier C, et al
    Hospital burden of pulmonary arterial hypertension in France.
    PLoS One. 2019;14:e0221211.
    PubMed     Abstract available


  57. ABSI M, Eid BG, Ashton N, Hart G, et al
    Simvastatin causes pulmonary artery relaxation by blocking smooth muscle ROCK and calcium channels: Evidence for an endothelium-independent mechanism.
    PLoS One. 2019;14:e0220473.
    PubMed     Abstract available


  58. CHAU Y, Li FS, Levsh O, Weng JK, et al
    Exploration of icariin analog structure space reveals key features driving potent inhibition of human phosphodiesterase-5.
    PLoS One. 2019;14:e0222803.
    PubMed     Abstract available


  59. AXELSEN JB, Andersen S, Sun XQ, Ringgaard S, et al
    Effects of 6-mercaptopurine in pressure overload induced right heart failure.
    PLoS One. 2019;14:e0225122.
    PubMed     Abstract available


    January 2018
  60. DEY S, Parveen A, Tarrant KJ, Licknack T, et al
    Whole genome resequencing identifies the CPQ gene as a determinant of ascites syndrome in broilers.
    PLoS One. 2018;13:e0189544.
    PubMed     Abstract available


  61. GREINER S, Jud A, Aurich M, Geisenberger C, et al
    Prognostic relevance of elevated pulmonary arterial pressure assessed non-invasively: Analysis in a large patient cohort with invasive measurements in near temporal proximity.
    PLoS One. 2018;13:e0191206.
    PubMed     Abstract available


  62. CHAMORRO V, Morales-Cano D, Milara J, Barreira B, et al
    Riociguat versus sildenafil on hypoxic pulmonary vasoconstriction and ventilation/perfusion matching.
    PLoS One. 2018;13:e0191239.
    PubMed     Abstract available


  63. KHIRFAN G, Naal T, Abuhalimeh B, Newman J, et al
    Hypoxemia in patients with idiopathic or heritable pulmonary arterial hypertension.
    PLoS One. 2018;13:e0191869.
    PubMed     Abstract available


  64. ALENCAR AK, Carvalho FI, Silva AM, Martinez ST, et al
    Synergistic interaction between a PDE5 inhibitor (sildenafil) and a new adenosine A2A receptor agonist (LASSBio-1359) improves pulmonary hypertension in rats.
    PLoS One. 2018;13:e0195047.
    PubMed     Abstract available


  65. LAUNAY D, Montani D, Hassoun PM, Cottin V, et al
    Clinical phenotypes and survival of pre-capillary pulmonary hypertension in systemic sclerosis.
    PLoS One. 2018;13:e0197112.
    PubMed     Abstract available


  66. KHIRFAN G, Tejwani V, Wang X, Li M, et al
    Plasma levels of high density lipoprotein cholesterol and outcomes in chronic thromboembolic pulmonary hypertension.
    PLoS One. 2018;13:e0197700.
    PubMed     Abstract available


  67. CARAVITA S, Faini A, Carolino D'Araujo S, Dewachter C, et al
    Clinical phenotypes and outcomes of pulmonary hypertension due to left heart disease: Role of the pre-capillary component.
    PLoS One. 2018;13:e0199164.
    PubMed     Abstract available


  68. SOUZA R, Channick RN, Delcroix M, Galie N, et al
    Association between six-minute walk distance and long-term outcomes in patients with pulmonary arterial hypertension: Data from the randomized SERAPHIN trial.
    PLoS One. 2018;13:e0193226.
    PubMed     Abstract available


  69. DONDA K, Zambrano R, Moon Y, Percival J, et al
    Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth.
    PLoS One. 2018;13:e0199927.
    PubMed     Abstract available


  70. STEPNOWSKA E, Lewicka E, Dabrowska-Kugacka A, Danilowicz-Szymanowicz L, et al
    Predictors of poor outcome in patients with pulmonary arterial hypertension: A single center study.
    PLoS One. 2018;13:e0193245.
    PubMed     Abstract available


  71. MIHARA K, Ogawa A, Matsubara H, Terao T, et al
    Investigation of safety and efficacy of the new more thermostable formulation of Flolan (epoprostenol) in Japanese patients with pulmonary arterial hypertension (PAH)-An open-label, single-arm study.
    PLoS One. 2018;13:e0195195.
    PubMed     Abstract available


  72. GROSSE A, Grosse C, Lang I
    Evaluation of the CT imaging findings in patients newly diagnosed with chronic thromboembolic pulmonary hypertension.
    PLoS One. 2018;13:e0201468.
    PubMed     Abstract available


  73. VIJARNSORN C, Durongpisitkul K, Chungsomprasong P, Bositthipichet D, et al
    Contemporary survival of patients with pulmonary arterial hypertension and congenital systemic to pulmonary shunts.
    PLoS One. 2018;13:e0195092.
    PubMed     Abstract available


  74. WILSON JL, Warburton R, Taylor L, Toksoz D, et al
    Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension.
    PLoS One. 2018;13:e0195780.
    PubMed     Abstract available


  75. SHAH AC, Ma K, Faraoni D, Oh DCS, et al
    Self-reported functional status predicts post-operative outcomes in non-cardiac surgery patients with pulmonary hypertension.
    PLoS One. 2018;13:e0201914.
    PubMed     Abstract available


  76. SONNWEBER T, Nairz M, Theurl I, Petzer V, et al
    The crucial impact of iron deficiency definition for the course of precapillary pulmonary hypertension.
    PLoS One. 2018;13:e0203396.
    PubMed     Abstract available


  77. ROLIM JV, Ota-Arakaki JS, Ferreira EVM, Figliolino GAM, et al
    Inspiratory muscle weakness contributes to exertional dyspnea in chronic thromboembolic pulmonary hypertension.
    PLoS One. 2018;13:e0204072.
    PubMed     Abstract available


  78. KRIECHBAUM SD, Wiedenroth CB, Keller T, Wolter JS, et al
    Dynamics of high-sensitivity cardiac troponin T during therapy with balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension.
    PLoS One. 2018;13:e0204683.
    PubMed     Abstract available


  79. GUAY CA, Morin-Thibault LV, Bonnet S, Lacasse Y, et al
    Pulmonary hypertension-targeted therapies in heart failure: A systematic review and meta-analysis.
    PLoS One. 2018;13:e0204610.
    PubMed     Abstract available


  80. TAKAHASHI T, Yoshihisa A, Sugimoto K, Yokokawa T, et al
    Associations between diabetes mellitus and pulmonary hypertension in chronic respiratory disease patients.
    PLoS One. 2018;13:e0205008.
    PubMed     Abstract available


  81. DRIESSEN MMP, Leiner T, Sieswerda GT, van Dijk APJ, et al
    RV adaptation to increased afterload in congenital heart disease and pulmonary hypertension.
    PLoS One. 2018;13:e0205196.
    PubMed     Abstract available


  82. SATO T, Hatano M, Iwasaki Y, Maki H, et al
    Prevalence of primary Sjogren's syndrome in patients undergoing evaluation for pulmonary arterial hypertension.
    PLoS One. 2018;13:e0197297.
    PubMed     Abstract available


  83. IGATA S, Tahara N, Sugiyama Y, Bekki M, et al
    Utility of the amplitude of RV1+SV5/6 in assessment of pulmonary hypertension.
    PLoS One. 2018;13:e0206856.
    PubMed     Abstract available


  84. GHIO S, Crimi G, Pica S, Temporelli PL, et al
    Correction: Persistent abnormalities in pulmonary arterial compliance after heart transplantation in patients with combined post-capillary and pre-capillary pulmonary hypertension.
    PLoS One. 2018;13:e0208863.
    PubMed     Abstract available


  85. DAVIS EM, Baust JJ, O'Donnell BJ, Shah FA, et al
    A phenotype of increased sleepiness in a mouse model of pulmonary hypertension and right ventricular hypertrophy.
    PLoS One. 2018;13:e0208540.
    PubMed     Abstract available


  86. TROMEUR C, Jais X, Mercier O, Couturaud F, et al
    Factors predicting outcome after pulmonary endarterectomy.
    PLoS One. 2018;13:e0198198.
    PubMed     Abstract available


  87. KURDYUKOV S, Eccles CA, Desai AA, Gonzalez-Garay M, et al
    New cases of Glucose-6-Phosphate Dehydrogenase deficiency in Pulmonary Arterial Hypertension.
    PLoS One. 2018;13:e0203493.
    PubMed     Abstract available


  88. NAKAMURA K, Sakaguchi M, Matsubara H, Akagi S, et al
    Crucial role of RAGE in inappropriate increase of smooth muscle cells from patients with pulmonary arterial hypertension.
    PLoS One. 2018;13:e0203046.
    PubMed     Abstract available


  89. FUJITA N, Yamasaki N, Eto K, Asaeda M, et al
    Oxygen therapy may worsen the survival rate in rats with monocrotaline-induced pulmonary arterial hypertension.
    PLoS One. 2018;13:e0204254.
    PubMed     Abstract available


  90. ZANTE B, Reichenspurner H, Kubik M, Kluge S, et al
    Base excess is superior to lactate-levels in prediction of ICU mortality after cardiac surgery.
    PLoS One. 2018;13:e0205309.
    PubMed     Abstract available


  91. LAMBERS C, Kornauth C, Oberndorfer F, Boehm PM, et al
    Mechanism of anti-remodelling action of treprostinil in human pulmonary arterial smooth muscle cells.
    PLoS One. 2018;13:e0205195.
    PubMed     Abstract available


  92. HOFFMANN-VOLD AM, Weigt SS, Palchevskiy V, Volkmann E, et al
    Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis.
    PLoS One. 2018;13:e0206545.
    PubMed     Abstract available


  93. SONG S, Lee SE, Oh SK, Jeon SA, et al
    Demographics, treatment trends, and survival rate in incident pulmonary artery hypertension in Korea: A nationwide study based on the health insurance review and assessment service database.
    PLoS One. 2018;13:e0209148.
    PubMed     Abstract available


    January 2017
  94. GOTTING M, Schwarzer M, Gerber A, Klingelhofer D, et al
    Pulmonary Hypertension: Scientometric Analysis and Density-Equalizing Mapping.
    PLoS One. 2017;12:e0169238.
    PubMed     Abstract available


  95. HIMORI K, Abe M, Tatebayashi D, Lee J, et al
    Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension.
    PLoS One. 2017;12:e0169146.
    PubMed     Abstract available


  96. DUMAS DE LA ROQUE E, Smeralda G, Quignard JF, Freund-Michel V, et al
    Altered vasoreactivity in neonatal rats with pulmonary hypertension associated with bronchopulmonary dysplasia: Implication of both eNOS phosphorylation and calcium signaling.
    PLoS One. 2017;12:e0173044.
    PubMed     Abstract available


  97. WANG X, Shults NV, Suzuki YJ
    Oxidative profiling of the failing right heart in rats with pulmonary hypertension.
    PLoS One. 2017;12:e0176887.
    PubMed     Abstract available


  98. TANAKA H, Kataoka M, Isobe S, Yamamoto T, et al
    Therapeutic impact of dietary vitamin D supplementation for preventing right ventricular remodeling and improving survival in pulmonary hypertension.
    PLoS One. 2017;12:e0180615.
    PubMed     Abstract available


  99. PEREZ M, Lee KJ, Cardona HJ, Taylor JM, et al
    Aberrant cGMP signaling persists during recovery in mice with oxygen-induced pulmonary hypertension.
    PLoS One. 2017;12:e0180957.
    PubMed     Abstract available


  100. SZEMA AM, Forsyth E, Ying B, Hamidi SA, et al
    NFATc3 and VIP in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease.
    PLoS One. 2017;12:e0170606.
    PubMed     Abstract available


  101. MIDDLETON RC, Fournier M, Xu X, Marban E, et al
    Therapeutic benefits of intravenous cardiosphere-derived cell therapy in rats with pulmonary hypertension.
    PLoS One. 2017;12:e0183557.
    PubMed     Abstract available


  102. LOOMIS Z, Eigenberger P, Redinius K, Lisk C, et al
    Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation.
    PLoS One. 2017;12:e0171219.
    PubMed     Abstract available


  103. POOR HD, Kawut SM, Liu CY, Smith BM, et al
    Pulmonary hyperinflation due to gas trapping and pulmonary artery size: The MESA COPD Study.
    PLoS One. 2017;12:e0176812.
    PubMed     Abstract available


  104. SOKUNBI OJ, Ekure EN, Temiye EO, Anyanwu R, et al
    Pulmonary hypertension among 5 to 18 year old children with sickle cell anaemia in Nigeria.
    PLoS One. 2017;12:e0184287.
    PubMed     Abstract available


  105. LAN CC, Peng CK, Tang SE, Huang KL, et al
    Carbonic anhydrase inhibitor attenuates ischemia-reperfusion induced acute lung injury.
    PLoS One. 2017;12:e0179822.
    PubMed     Abstract available


  106. FUCHS H, Rossmann N, Schmid MB, Hoenig M, et al
    Permissive hypercapnia for severe acute respiratory distress syndrome in immunocompromised children: A single center experience.
    PLoS One. 2017;12:e0179974.
    PubMed     Abstract available


  107. REVUZ S, Decullier E, Ginon I, Lamblin N, et al
    Pulmonary hypertension subtypes associated with hereditary haemorrhagic telangiectasia: Haemodynamic profiles and survival probability.
    PLoS One. 2017;12:e0184227.
    PubMed     Abstract available


  108. JERNIGAN NL, Naik JS, Weise-Cross L, Detweiler ND, et al
    Contribution of reactive oxygen species to the pathogenesis of pulmonary arterial hypertension.
    PLoS One. 2017;12:e0180455.
    PubMed     Abstract available


  109. ZUNGU-EDMONDSON M, Shults NV, Melnyk O, Suzuki YJ, et al
    Natural reversal of pulmonary vascular remodeling and right ventricular remodeling in SU5416/hypoxia-treated Sprague-Dawley rats.
    PLoS One. 2017;12:e0182551.
    PubMed     Abstract available


  110. LE GOUELLEC N, Duhamel A, Perez T, Hachulla AL, et al
    Predictors of lung function test severity and outcome in systemic sclerosis-associated interstitial lung disease.
    PLoS One. 2017;12:e0181692.
    PubMed     Abstract available


  111. SUGIMOTO K, Nakazato K, Sato A, Suzuki S, et al
    Autoimmune disease mouse model exhibits pulmonary arterial hypertension.
    PLoS One. 2017;12:e0184990.
    PubMed     Abstract available


  112. VENTETUOLO CE, Hess E, Austin ED, Baron AE, et al
    Sex-based differences in veterans with pulmonary hypertension: Results from the veterans affairs-clinical assessment reporting and tracking database.
    PLoS One. 2017;12:e0187734.
    PubMed     Abstract available


  113. SATO T, Tsujino I, Ohira H, Oyama-Manabe N, et al
    Accuracy of echocardiographic indices for serial monitoring of right ventricular systolic function in patients with precapillary pulmonary hypertension.
    PLoS One. 2017;12:e0187806.
    PubMed     Abstract available


  114. GHIO S, Crimi G, Pica S, Temporelli PL, et al
    Persistent abnormalities in pulmonary arterial compliance after heart transplantation in patients with combined post-capillary and pre-capillary pulmonary hypertension.
    PLoS One. 2017;12:e0188383.
    PubMed     Abstract available


  115. LOPEZ-MESEGUER M, Quezada CA, Ramon MA, Lazaro M, et al
    Lung and heart-lung transplantation in pulmonary arterial hypertension.
    PLoS One. 2017;12:e0187811.
    PubMed     Abstract available


    January 2016
  116. XI Q, Liu Z, Zhao Z, Luo Q, et al
    High Frequency of Pulmonary Hypertension-Causing Gene Mutation in Chinese Patients with Chronic Thromboembolic Pulmonary Hypertension.
    PLoS One. 2016;11:e0147396.
    PubMed     Abstract available


  117. GUBRIJ IB, Pangle AK, Pang L, Johnson LG, et al
    Reversal of MicroRNA Dysregulation in an Animal Model of Pulmonary Hypertension.
    PLoS One. 2016;11:e0147827.
    PubMed     Abstract available


  118. LI Q, Mao M, Qiu Y, Liu G, et al
    Key Role of ROS in the Process of 15-Lipoxygenase/15-Hydroxyeicosatetraenoiccid-Induced Pulmonary Vascular Remodeling in Hypoxia Pulmonary Hypertension.
    PLoS One. 2016;11:e0149164.
    PubMed     Abstract available


  119. RAFIKOVA O, Meadows ML, Kinchen JM, Mohney RP, et al
    Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung.
    PLoS One. 2016;11:e0150480.
    PubMed     Abstract available


  120. RICHTER MJ, Milger K, Haase S, Sommer N, et al
    The Clinical Significance of HbA1c in Operable Chronic Thromboembolic Pulmonary Hypertension.
    PLoS One. 2016;11:e0152580.
    PubMed     Abstract available


  121. YIN X, Wang L, Qin G, Luo H, et al
    Rats with Chronic, Stable Pulmonary Hypertension Tolerate Low Dose Sevoflurane Inhalation as Well as Normal Rats Do.
    PLoS One. 2016;11:e0154154.
    PubMed     Abstract available


  122. PAGANO JJ, Chow K, Khan A, Michelakis E, et al
    Reduced Right Ventricular Native Myocardial T1 in Anderson-Fabry Disease: Comparison to Pulmonary Hypertension and Healthy Controls.
    PLoS One. 2016;11:e0157565.
    PubMed     Abstract available


  123. WANG Q, Guo YZ, Zhang YT, Xue JJ, et al
    The Effects and Mechanism of Atorvastatin on Pulmonary Hypertension Due to Left Heart Disease.
    PLoS One. 2016;11:e0157171.
    PubMed     Abstract available


  124. YANG L, Yu D, Mo R, Zhang J, et al
    The Succinate Receptor GPR91 Is Involved in Pressure Overload-Induced Ventricular Hypertrophy.
    PLoS One. 2016;11:e0147597.
    PubMed     Abstract available


  125. HUANG WC, Ke MW, Cheng CC, Chiou SH, et al
    Therapeutic Benefits of Induced Pluripotent Stem Cells in Monocrotaline-Induced Pulmonary Arterial Hypertension.
    PLoS One. 2016;11:e0142476.
    PubMed     Abstract available


  126. NIELSEN EA, Sun M, Honjo O, Hjortdal VE, et al
    Dual Endothelin Receptor Blockade Abrogates Right Ventricular Remodeling and Biventricular Fibrosis in Isolated Elevated Right Ventricular Afterload.
    PLoS One. 2016;11:e0146767.
    PubMed     Abstract available


  127. WEST JD, Carrier EJ, Bloodworth NC, Schroer AK, et al
    Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension.
    PLoS One. 2016;11:e0148657.
    PubMed     Abstract available


  128. PARIKH RV, Ma Y, Scherzer R, Heringer AS, et al
    Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection.
    PLoS One. 2016;11:e0146355.
    PubMed     Abstract available


  129. GALAMBOS C, Minic AD, Bush D, Nguyen D, et al
    Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension.
    PLoS One. 2016;11:e0159005.
    PubMed     Abstract available


  130. AL-ALLAWI N, Mohammad AM, Jamal S
    Doppler-Defined Pulmonary Hypertension in Sickle Cell Anemia in Kurdistan, Iraq.
    PLoS One. 2016;11:e0162036.
    PubMed     Abstract available


  131. JUJO T, Tanabe N, Sakao S, Ishibashi-Ueda H, et al
    Severe Pulmonary Arteriopathy Is Associated with Persistent Hypoxemia after Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension.
    PLoS One. 2016;11:e0161827.
    PubMed     Abstract available


  132. RENGIER F, Worz S, Melzig C, Ley S, et al
    Automated 3D Volumetry of the Pulmonary Arteries based on Magnetic Resonance Angiography Has Potential for Predicting Pulmonary Hypertension.
    PLoS One. 2016;11:e0162516.
    PubMed     Abstract available


  133. COLLACO JM, Dadlani GH, Nies MK, Leshko J, et al
    Risk Factors and Clinical Outcomes in Preterm Infants with Pulmonary Hypertension.
    PLoS One. 2016;11:e0163904.
    PubMed     Abstract available


  134. RICHTER MJ, Tiede SL, Sommer N, Schmidt T, et al
    Circulating Angiopoietin-1 Is Not a Biomarker of Disease Severity or Prognosis in Pulmonary Hypertension.
    PLoS One. 2016;11:e0165982.
    PubMed     Abstract available


  135. SUGIMOTO K, Yoshihisa A, Nakazato K, Jin Y, et al
    Pulmonary Arterial Capacitance Predicts Cardiac Events in Pulmonary Hypertension Due to Left Heart Disease.
    PLoS One. 2016;11:e0165603.
    PubMed     Abstract available


  136. JANKOWICH M, Elston B, Evans SK, Wu WC, et al
    Relationship of Iron Deficiency and Serum Ferritin Levels with Pulmonary Hypertension: The Jackson Heart Study.
    PLoS One. 2016;11:e0167987.
    PubMed     Abstract available


  137. KOVACS G, Avian A, Foris V, Tscherner M, et al
    Use of ECG and Other Simple Non-Invasive Tools to Assess Pulmonary Hypertension.
    PLoS One. 2016;11:e0168706.
    PubMed     Abstract available


  138. WANG L, Qu M, Chen Y, Zhou Y, et al
    Statins Have No Additional Benefit for Pulmonary Hypertension: A Meta-Analysis of Randomized Controlled Trials.
    PLoS One. 2016;11:e0168101.
    PubMed     Abstract available


  139. PARK DW, Sebastiani A, Yap CH, Simon MA, et al
    Quantification of Coupled Stiffness and Fiber Orientation Remodeling in Hypertensive Rat Right-Ventricular Myocardium Using 3D Ultrasound Speckle Tracking with Biaxial Testing.
    PLoS One. 2016;11:e0165320.
    PubMed     Abstract available


  140. FARHA S, Hu B, Comhair S, Zein J, et al
    Mitochondrial Haplogroups and Risk of Pulmonary Arterial Hypertension.
    PLoS One. 2016;11:e0156042.
    PubMed     Abstract available


  141. SAHOO S, Meijles DN, Al Ghouleh I, Tandon M, et al
    MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension.
    PLoS One. 2016;11:e0153780.
    PubMed     Abstract available


  142. WU Y, Adi D, Long M, Wang J, et al
    4-Phenylbutyric Acid Induces Protection against Pulmonary Arterial Hypertension in Rats.
    PLoS One. 2016;11:e0157538.
    PubMed     Abstract available


  143. ROSE JA, Wanner N, Cheong HI, Queisser K, et al
    Flow Cytometric Quantification of Peripheral Blood Cell beta-Adrenergic Receptor Density and Urinary Endothelial Cell-Derived Microparticles in Pulmonary Arterial Hypertension.
    PLoS One. 2016;11:e0156940.
    PubMed     Abstract available


  144. BUJAK R, Mateo J, Blanco I, Izquierdo-Garcia JL, et al
    New Biochemical Insights into the Mechanisms of Pulmonary Arterial Hypertension in Humans.
    PLoS One. 2016;11:e0160505.
    PubMed     Abstract available


    January 2015
  145. LAI YJ, Chang GJ, Yeh YH, Pang JH, et al
    Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase.
    PLoS One. 2015;10:e0137426.
    PubMed     Abstract available


  146. KOHYAMA T, Moriyama K, Kanai R, Kotani M, et al
    Correction: Accuracy of Pulse Oximeters in Detecting Hypoxemia in Patients with Chronic Thromboembolic Pulmonary Hypertension.
    PLoS One. 2015;10:e0141944.
    PubMed     Abstract available


  147. HOEPER MM, Behr J, Held M, Grunig E, et al
    Pulmonary Hypertension in Patients with Chronic Fibrosing Idiopathic Interstitial Pneumonias.
    PLoS One. 2015;10:e0141911.
    PubMed     Abstract available


  148. MCCULLAGH BN, Costello CM, Li L, O'Connell C, et al
    Elevated Plasma CXCL12alpha Is Associated with a Poorer Prognosis in Pulmonary Arterial Hypertension.
    PLoS One. 2015;10:e0123709.
    PubMed     Abstract available


  149. OTSUKI S, Sawada H, Yodoya N, Shinohara T, et al
    Potential contribution of phenotypically modulated smooth muscle cells and related inflammation in the development of experimental obstructive pulmonary vasculopathy in rats.
    PLoS One. 2015;10:e0118655.
    PubMed     Abstract available


  150. AGUERO J, Ishikawa K, Fish KM, Hammoudi N, et al
    Combination proximal pulmonary artery coiling and distal embolization induces chronic elevations in pulmonary artery pressure in Swine.
    PLoS One. 2015;10:e0124526.
    PubMed     Abstract available


  151. PROVENCHER S, Paruchuru P, Spezzi A, Waterhouse B, et al
    Quality of life, safety and efficacy profile of thermostable flolan in pulmonary arterial hypertension.
    PLoS One. 2015;10:e0120657.
    PubMed     Abstract available


  152. SWIFT AJ, Capener D, Hammerton C, Thomas SM, et al
    Right ventricular sex differences in patients with idiopathic pulmonary arterial hypertension characterised by magnetic resonance imaging: pair-matched case controlled study.
    PLoS One. 2015;10:e0127415.
    PubMed     Abstract available


  153. KIMURA M, Tamura Y, Takei M, Yamamoto T, et al
    Rapid initiation of intravenous epoprostenol infusion is the favored option in patients with advanced pulmonary arterial hypertension.
    PLoS One. 2015;10:e0121894.
    PubMed     Abstract available


  154. WILSON JL, Yu J, Taylor L, Polgar P, et al
    Hyperplastic Growth of Pulmonary Artery Smooth Muscle Cells from Subjects with Pulmonary Arterial Hypertension Is Activated through JNK and p38 MAPK.
    PLoS One. 2015;10:e0123662.
    PubMed     Abstract available


  155. VIALES RR, Eichstaedt CA, Ehlken N, Fischer C, et al
    Mutation in BMPR2 Promoter: A 'Second Hit' for Manifestation of Pulmonary Arterial Hypertension?
    PLoS One. 2015;10:e0133042.
    PubMed     Abstract available


  156. ZHAO YD, Chu L, Lin K, Granton E, et al
    A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung.
    PLoS One. 2015;10:e0134958.
    PubMed     Abstract available


  157. YAMAMURA A, Ohara N, Tsukamoto K
    Inhibition of Excessive Cell Proliferation by Calcilytics in Idiopathic Pulmonary Arterial Hypertension.
    PLoS One. 2015;10:e0138384.
    PubMed     Abstract available


  158. HAN QJ, Witschey WR, Fang-Yen CM, Arkles JS, et al
    Altered Right Ventricular Kinetic Energy Work Density and Viscous Energy Dissipation in Patients with Pulmonary Arterial Hypertension: A Pilot Study Using 4D Flow MRI.
    PLoS One. 2015;10:e0138365.
    PubMed     Abstract available


  159. ELGENDI M, Kumar S, Guo L, Rutledge J, et al
    Detection of Heart Sounds in Children with and without Pulmonary Arterial Hypertension-Daubechies Wavelets Approach.
    PLoS One. 2015;10:e0143146.
    PubMed     Abstract available


    January 2014
  160. POUSADA G, Baloira A, Vilarino C, Cifrian JM, et al
    Novel Mutations in BMPR2, ACVRL1 and KCNA5 Genes and Hemodynamic Parameters in Patients with Pulmonary Arterial Hypertension.
    PLoS One. 2014;9:e100261.
    PubMed     Abstract available


  161. SADAMURA-TAKENAKA Y, Ito T, Noma S, Oyama Y, et al
    HMGB1 Promotes the Development of Pulmonary Arterial Hypertension in Rats.
    PLoS One. 2014;9:e102482.
    PubMed     Abstract available


  162. SUN LY, Zhao H, Kang Y, Shen XD, et al
    Two-dimensional echocardiography in the assessment of long-term prognosis in patients with pulmonary arterial hypertension.
    PLoS One. 2014;9:e114443.
    PubMed     Abstract available


  163. BREDA AP, Pereira de Albuquerque AL, Jardim C, Morinaga LK, et al
    Skeletal muscle abnormalities in pulmonary arterial hypertension.
    PLoS One. 2014;9:e114101.
    PubMed     Abstract available


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