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  Pulmonary Hypertension

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Articles published in Am J Physiol Heart Circ Physiol

Retrieve available abstracts of 31 articles:
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Single Articles


    December 2023
  1. HANSEN TS, Karimi Galougahi K, Tang O, Tsang M, et al
    The FXYD1 protein plays a protective role against pulmonary hypertension and arterial remodelling via redox and inflammatory mechanisms.
    Am J Physiol Heart Circ Physiol. 2023 Dec 22. doi: 10.1152/ajpheart.00090.2023.
    PubMed     Abstract available


    June 2023
  2. MCNAIR BD, Polson SM, Shorthill SK, Yusifov A, et al
    Metformin protects against pulmonary hypertension-induced right ventricular dysfunction in an age- and sex-specific manner independent of cardiac AMPK.
    Am J Physiol Heart Circ Physiol. 2023 Jun 30. doi: 10.1152/ajpheart.00124.2023.
    PubMed     Abstract available


    March 2023
  3. BROWN RD, Hunter KS, Li M, Frid MG, et al
    Functional and Molecular Determinants of Right Ventricular Response to Severe Pulmonary Hypertension in a Large Animal Model.
    Am J Physiol Heart Circ Physiol. 2023 Mar 24. doi: 10.1152/ajpheart.00614.2022.
    PubMed     Abstract available


    October 2022
  4. FRIED ND, Whitehead A, Lazartigues E, Yue X, et al
    Ovarian hormones do not mediate protection against pulmonary hypertension and right ventricular remodeling in female mice exposed to chronic, inhaled nicotine.
    Am J Physiol Heart Circ Physiol. 2022 Oct 7. doi: 10.1152/ajpheart.00467.2022.
    PubMed     Abstract available


    September 2022
  5. TIAN S, Cai Z, Sen P, van Uden D, et al
    Loss of lung microvascular endothelial Piezo2 expression impairs NO synthesis, induces EndMT and is associated with pulmonary hypertension.
    Am J Physiol Heart Circ Physiol. 2022 Sep 23. doi: 10.1152/ajpheart.00220.2022.
    PubMed     Abstract available


    February 2022
  6. CHRISTOU H, Khalil RA
    Mechanisms of Pulmonary Vascular Dysfunction in Pulmonary Hypertension and Implications for Novel Therapies.
    Am J Physiol Heart Circ Physiol. 2022 Feb 25. doi: 10.1152/ajpheart.00021.2022.
    PubMed     Abstract available


    November 2021
  7. OLSEN NT, Goransson C, Vejlstrup N, Carlsen J, et al
    Myocardial adaptation and exercise performance in patients with pulmonary arterial hypertension assessed with patient-specific computer simulations.
    Am J Physiol Heart Circ Physiol. 2021;321:H865-H880.
    PubMed     Abstract available


    October 2021
  8. KWAN ED, Velez-Rendon D, Zhang X, Mu H, et al
    Distinct time courses and mechanics of right ventricular hypertrophy and diastolic stiffening in a male rat model of pulmonary arterial hypertension.
    Am J Physiol Heart Circ Physiol. 2021;321:H702-H715.
    PubMed     Abstract available


    September 2021
  9. LANG IM, Thurner S
    Computer modeling to predict balloon pulmonary angioplasty success.
    Am J Physiol Heart Circ Physiol. 2021;321:H567-H568.
    PubMed    


    July 2021
  10. SAHOO S, Li Y, de Jesus D, Sembrat JC, et al
    Notch2 Suppression Mimicking Changes in Human Pulmonary Hypertension Modulates Notch1 and Promotes Endothelial Cell Proliferation.
    Am J Physiol Heart Circ Physiol. 2021 Jul 23. doi: 10.1152/ajpheart.00125.2021.
    PubMed     Abstract available


    June 2021
  11. VU LD, Saravia J, Jaligama S, Baboeram Panday RV, et al
    Deficiency of ST2 signaling ameliorates RSV-associated pulmonary hypertension.
    Am J Physiol Heart Circ Physiol. 2021 Jun 25. doi: 10.1152/ajpheart.00018.2021.
    PubMed     Abstract available


  12. FERGUSON BS, Wennersten SA, Demos-Davies KM, Rubino M, et al
    DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy.
    Am J Physiol Heart Circ Physiol. 2021 Jun 18. doi: 10.1152/ajpheart.00115.2021.
    PubMed     Abstract available


  13. COLEBANK MJ, Qureshi MU, Rajagopal S, Krasuski RA, et al
    A multiscale model of vascular function in chronic thromboembolic pulmonary hypertension.
    Am J Physiol Heart Circ Physiol. 2021 Jun 18. doi: 10.1152/ajpheart.00086.2021.
    PubMed     Abstract available


  14. SCHAFER M, Ivy DD, Nguyen K, Boncella KL, et al
    Metalloproteinases and Their Inhibitors Are Associated with Pulmonary Arterial Stiffness and Ventricular Function in Pediatric Pulmonary Hypertension.
    Am J Physiol Heart Circ Physiol. 2021 Jun 4. doi: 10.1152/ajpheart.00750.2020.
    PubMed     Abstract available


    February 2021
  15. FRIED ND, Morris TM, Whitehead A, Lazartigues E, et al
    Angiotensin-II type 1 receptor mediates pulmonary hypertension and right ventricular remodeling induced by inhaled nicotine.
    Am J Physiol Heart Circ Physiol. 2021 Feb 12. doi: 10.1152/ajpheart.00883.2020.
    PubMed     Abstract available


    January 2021
  16. INAGAKI T, Pearson JT, Tsuchimochi H, Schwenke DO, et al
    Evaluation of right coronary vascular dysfunction in severe pulmonary hypertensive rats using synchrotron radiation microangiography.
    Am J Physiol Heart Circ Physiol. 2021 Jan 22. doi: 10.1152/ajpheart.00327.2020.
    PubMed     Abstract available


  17. MUNDO W, Wolfson G, Moore LG, Houck JA, et al
    Hypoxia-induced inhibition of mTORC1 activity in the developing lung: a possible mechanism for the developmental programming of pulmonary hypertension.
    Am J Physiol Heart Circ Physiol. 2021 Jan 8. doi: 10.1152/ajpheart.00520.2020.
    PubMed     Abstract available


    October 2020
  18. FUKUMITSU M, Westerhof BE, Ruigrok D, Braams NJ, et al
    Early return of reflected waves increases right ventricular wall stress in chronic thromboembolic pulmonary hypertension.
    Am J Physiol Heart Circ Physiol. 2020 Oct 9. doi: 10.1152/ajpheart.00442.2020.
    PubMed     Abstract available


    September 2020
  19. YAMANAKA R, Hoshino A, Fukai K, Urata R, et al
    TIGAR reduces smooth muscle cell autophagy to prevent pulmonary hypertension.
    Am J Physiol Heart Circ Physiol. 2020 Sep 18. doi: 10.1152/ajpheart.00314.2020.
    PubMed     Abstract available


    August 2020
  20. LEI S, Peng F, Li ML, Duan WB, et al
    LncRNA-SMILR modulates RhoA/ROCK signaling by targeting miR-141 to regulate vascular remodeling in pulmonary arterial hypertension.
    Am J Physiol Heart Circ Physiol. 2020;319:H377-H391.
    PubMed     Abstract available


    May 2020
  21. HANSEN T, Galougahi KK, Besnier M, Genetzakis E, et al
    The Novel P2X7 Receptor PKT100 Improves Right Ventricular Function and Survival in Pulmonary Hypertension.
    Am J Physiol Heart Circ Physiol. 2020 May 29. doi: 10.1152/ajpheart.00580.2019.
    PubMed     Abstract available


    April 2020
  22. KANG Y, Zhang G, Huang EC, Huang J, et al
    Sulforaphane prevents right ventricular injury and reduces pulmonary vascular remodeling in pulmonary arterial hypertension.
    Am J Physiol Heart Circ Physiol. 2020;318:H853-H866.
    PubMed     Abstract available


    February 2020
  23. FRANK BS, Schafer M, Douwes JM, Ivy DD, et al
    Novel measures of left ventricular electromechanical discoordination predict clinical outcomes in children with pulmonary arterial hypertension.
    Am J Physiol Heart Circ Physiol. 2020;318:H401-H412.
    PubMed     Abstract available


    December 2019
  24. ALENEZI F, Rajagopal S, Kutty S
    Assessing Right Atrial Function in Pulmonary Hypertension -a Window to the Soul of the Right Heart?
    Am J Physiol Heart Circ Physiol. 2019 Dec 20. doi: 10.1152/ajpheart.00739.2019.
    PubMed    


    November 2019
  25. TELLO K, Dalmer A, Vanderpool RR, Ghofrani HA, et al
    Right ventricular function correlates of right atrial strain in pulmonary hypertension: a combined cardiac magnetic resonance and conductance catheter study.
    Am J Physiol Heart Circ Physiol. 2019 Nov 22. doi: 10.1152/ajpheart.00485.2019.
    PubMed     Abstract available


  26. FINSBERG HNT, Sundnes JS, Xi C, Lee LC, et al
    Computational quantification of patient specific changes in ventricular dynamics associated with pulmonary hypertension.
    Am J Physiol Heart Circ Physiol. 2019 Nov 1. doi: 10.1152/ajpheart.00094.2019.
    PubMed     Abstract available


    September 2019
  27. SU J, Hughes AD, Simonsen U, Nielsen-Kudsk JE, et al
    Impact of pulmonary endarterectomy on pulmonary arterial wave propagation and reservoir function.
    Am J Physiol Heart Circ Physiol. 2019;317:H505-H516.
    PubMed     Abstract available


    May 2019
  28. SCHMUCK EG, Hacker TA, Schreier DA, Chesler NC, et al
    Beneficial effects of mesenchymal stem cell delivery via a novel cardiac bioscaffold on right ventricles of pulmonary arterial hypertensive rats.
    Am J Physiol Heart Circ Physiol. 2019;316:H1005-H1013.
    PubMed     Abstract available


  29. SCHAFER M, Ivy DD, Abman SH, Stenmark K, et al
    Differences in pulmonary arterial flow hemodynamics between children and adults with pulmonary arterial hypertension as assessed by 4D-flow CMR studies.
    Am J Physiol Heart Circ Physiol. 2019;316:H1091-H1104.
    PubMed     Abstract available


  30. PHILIP JL, Murphy TM, Schreier DA, Stevens S, et al
    Pulmonary vascular mechanical consequences of ischemic heart failure and implications for right ventricular function.
    Am J Physiol Heart Circ Physiol. 2019;316:H1167-H1177.
    PubMed     Abstract available


  31. VANDEN EYNDEN F, El-Oumeiri B, Bove T, Van Nooten G, et al
    Proximal pressure reducing effect of wave reflection in the pulmonary circulation disappear in obstructive disease: insight from a rabbit model.
    Am J Physiol Heart Circ Physiol. 2019;316:H992-H1004.
    PubMed     Abstract available


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