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COVID-19: Daily Top 10 Papers


  Pulmonary Hypertension

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Articles published in Am J Physiol Lung Cell Mol Physiol

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Single Articles


    August 2021
  1. KASSA B, Kumar R, Mickael C, Sanders L, et al
    Endothelial Cell PHD2-HIF1alpha-PFKFB3 Contributes to Right Ventricle Vascular Adaptation in Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Aug 4. doi: 10.1152/ajplung.00351.2020.
    PubMed     Abstract available


    June 2021
  2. HYE T, Dwivedi P, Li W, Lahm T, et al
    Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021;320:L1025-L1037.
    PubMed     Abstract available


    May 2021
  3. AULAK KS, Al Abdi S, Li L, Crabb JS, et al
    Disease-specific platelet signaling defects in idiopathic pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021;320:L739-L749.
    PubMed     Abstract available


  4. WOODCOCK CC, Hafeez N, Handen A, Tang Y, et al
    Matrix stiffening induces a pathogenic QKI-miR-7-SRSF1 signaling axis in pulmonary arterial endothelial cells.
    Am J Physiol Lung Cell Mol Physiol. 2021;320:L726-L738.
    PubMed     Abstract available


    March 2021
  5. HADZIC S, Wu CY, Gredic M, Kojonazarov B, et al
    The effect of long-term doxycycline treatment in a mouse model of cigarette smoke-induced emphysema and pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Mar 24. doi: 10.1152/ajplung.00048.2021
    PubMed     Abstract available


  6. RICHTER MJ, Hsu S, Yogeswaran A, Husain-Syed F, et al
    Right ventricular pressure-volume loop shape and systolic pressure change in pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Mar 3. doi: 10.1152/ajplung.00583.2020.
    PubMed     Abstract available


    January 2021
  7. VALUPARAMPIL VARGHESE M, James J, Rafikova O, Rafikov R, et al
    Glucose-6 Phosphate dehydrogenase deficiency contributes to metabolic abnormality and pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Jan 27. doi: 10.1152/ajplung.00165.2020
    PubMed     Abstract available


    December 2020
  8. SHRESTHA AK, Menon RT, El-Saie A, Barrios R, et al
    Interactive and independent effects of early lipopolysaccharide and hyperoxia exposure on developing murine lungs.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L981-L996.
    PubMed     Abstract available


    November 2020
  9. YUAN C, Chen HX, Hou HT, Wang J, et al
    Protein biomarkers and risk scores in pulmonary arterial hypertension associated with ventricular septal defect: integration of multi-omics and validation.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L810-L822.
    PubMed     Abstract available


    October 2020
  10. CALLEJO M, Mondejar-Parreno G, Morales-Cano D, Barreira B, et al
    Vitamin D deficiency downregulates TASK-1 channels and induces pulmonary vascular dysfunction.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L627-L640.
    PubMed     Abstract available


    September 2020
  11. SHEAK JR, Jones DT, Lantz BJ, Maston LD, et al
    NFATc3 Regulation of Collagen V Expression Contributes to Cellular Immunity to Collagen Type V and Hypoxic Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020 Sep 30. doi: 10.1152/ajplung.00184.2020
    PubMed     Abstract available


  12. TAN R, Li J, Liu F, Liao P, et al
    Phenylalanine Induces Pulmonary Hypertension Through Calcium-Sensing Receptor Activation.
    Am J Physiol Lung Cell Mol Physiol. 2020 Sep 23. doi: 10.1152/ajplung.00215.2020
    PubMed     Abstract available


  13. LAHM T
    Taking it to heart: dissecting cardiopulmonary interactions in diseases of the lung and the cardiovascular system.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L547-L549.
    PubMed    


  14. LIN Q, Johns RA
    Resistin family proteins in pulmonary diseases.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L422-L434.
    PubMed     Abstract available


  15. KRISHNAN S, Stearman RS, Zeng L, Fisher A, et al
    Transcriptomic modifications in developmental cardiopulmonary adaptations to chronic hypoxia using a murine model of simulated high-altitude exposure.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L456-L470.
    PubMed     Abstract available


    August 2020
  16. ALAM P, Agarwal G, Kumar R, Mishra A, et al
    Susceptibility to high-altitude pulmonary edema is associated with circulating miRNA levels under hypobaric hypoxia conditions.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L360-L368.
    PubMed     Abstract available


    June 2020
  17. SZULCEK R, Grune J, Kuebler WM
    The updated cancer paradigm of PAH: recognizing complexity.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1111-L1114.
    PubMed    


  18. LEE JY, Francis CM, Bauer NN, Gassman NR, et al
    A cancer amidst us: the plexiform lesion in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1142-L1144.
    PubMed    


  19. FRUMP AL, Lai YC, Lahm T
    Assessing the cancer hypothesis of pulmonary arterial hypertension: the devil is in the detail.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1140-L1141.
    PubMed    


  20. CONDON D, Agarwal S, Chakraborty A, de Jesus Perez VA, et al
    The cancer hypothesis of pulmonary arterial hypertension: the next ten years.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1138-L1139.
    PubMed    


  21. COOL CD, Kuebler WM, Bogaard HJ, Spiekerkoetter E, et al
    The hallmarks of severe pulmonary arterial hypertension: the cancer hypothesis-ten years later.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1115-L1130.
    PubMed     Abstract available


    May 2020
  22. AGARWAL S, Sharma H, Chen L, Dhillon NK, et al
    NADPH oxidase-mediated endothelial injury in HIV- and opioid-induced pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1097-L1108.
    PubMed     Abstract available


  23. GIE AG, Salaets T, Vignero J, Regin Y, et al
    Intermittent CPAP limits hyperoxia-induced lung damage in a rabbit model of bronchopulmonary dysplasia.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L976-L987.
    PubMed     Abstract available


    April 2020
  24. MORTY RE
    World health days in May 2020: Pulmonary hypertension, asthma, and tobacco-, smoking-, and vaping-related disease in focus.
    Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1. doi: 10.1152/ajplung.00115.2020.
    PubMed    


  25. SHIMODA LA
    Know Your Enemy: Understanding the Pathophysiology of Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1. doi: 10.1152/ajplung.00111.2020.
    PubMed    


  26. CORRIS PA, Seeger W
    Call it by the correct name - pulmonary hypertension not pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1. doi: 10.1152/ajplung.00098.2020.
    PubMed    


    March 2020
  27. TUDER RM, Stenmark KR
    Perspective: Pathobiological paradigms in pulmonary hypertension, time for reappraisal.
    Am J Physiol Lung Cell Mol Physiol. 2020 Mar 18. doi: 10.1152/ajplung.00067.2020
    PubMed    


  28. JOSHI SR, Kitagawa A, Jacob C, Hashimoto R, et al
    Hypoxic Activation of G6PD Controls the Expression of Genes Involved in the Pathogenesis of Pulmonary Hypertension Through the Regulation of DNA Methylation.
    Am J Physiol Lung Cell Mol Physiol. 2020 Mar 11. doi: 10.1152/ajplung.00001.2020
    PubMed     Abstract available


  29. MCDOWELL RE, Aulak KS, Almoushref A, Melillo CA, et al
    Platelet glycolytic metabolism correlates with hemodynamic severity in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L562-L569.
    PubMed     Abstract available


    February 2020
  30. DIKALOVA A, Aschner JL, Kaplowitz MR, Cunningham G, et al
    Combined L-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
    Am J Physiol Lung Cell Mol Physiol. 2020 Feb 19. doi: 10.1152/ajplung.00280.2019
    PubMed     Abstract available


    January 2020
  31. ARJAANS S, Wagner BD, Mourani PM, Mandell EW, et al
    Early Angiogenic Proteins Associated with High Risk for Bronchopulmonary Dysplasia and Pulmonary Hypertension in Preterm Infants.
    Am J Physiol Lung Cell Mol Physiol. 2020 Jan 22. doi: 10.1152/ajplung.00131.2019
    PubMed     Abstract available


  32. HASHIMOTO R, Lanier GM, Dhagia V, Joshi S, et al
    Pluripotent HSCs Augment a-Adrenergic Receptor-Mediated Contraction of Pulmonary Artery and Contribute to the Pathogenesis of Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020 Jan 8. doi: 10.1152/ajplung.00327.2019.
    PubMed     Abstract available


  33. ELINOFF JM, Mazer AJ, Cai R, Lu M, et al
    Meta-analysis of blood genome-wide expression profiling studies in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L98-L111.
    PubMed     Abstract available


  34. NORVIK C, Westoo CK, Peruzzi N, Lovric G, et al
    Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L65-L75.
    PubMed     Abstract available


  35. BABICHEVA A, Ayon RJ, Zhao T, Ek Vitorin JF, et al
    MicroRNA-mediated downregulation of K(+) channels in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L10-L26.
    PubMed     Abstract available


    December 2019
  36. HE S, Ma C, Zhang L, Bai J, et al
    GLI1 mediated pulmonary artery smooth muscle cell pyroptosis contributes to hypoxia induced pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019 Dec 23. doi: 10.1152/ajplung.00405.2019
    PubMed     Abstract available


    November 2019
  37. CUSSAC LA, Cardouat G, Tiruchellvam Pillai N, Campagnac M, et al
    TRPV4 channel mediates adventitial fibroblast activation and adventitial remodeling in pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019 Nov 6. doi: 10.1152/ajplung.00084.2019.
    PubMed     Abstract available


    October 2019
  38. JALCE G, Guignabert C
    The Multiple Roles of Macrophage Migration Inhibitory Factor in Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019 Oct 2. doi: 10.1152/ajplung.00234.2019.
    PubMed     Abstract available


    August 2019
  39. GEORGE PM, Mitchell J
    Defining a pathological role for the vasculature in the development of fibrosis and pulmonary hypertension in interstitial lung disease.
    Am J Physiol Lung Cell Mol Physiol. 2019 Aug 21. doi: 10.1152/ajplung.00330.2019
    PubMed    


  40. PAUL T, Blanco I, Aguilar D, Tura-Ceide O, et al
    Therapeutic effects of soluble guanylate cyclase stimulation on pulmonary hemodynamics and emphysema development in guinea pigs chronically exposed to cigarette smoke.
    Am J Physiol Lung Cell Mol Physiol. 2019;317:L222-L234.
    PubMed     Abstract available


    July 2019
  41. OLIVEIRA AC, Fu C, Lu Y, Williams MA, et al
    Chemokine signaling axis between endothelial and myeloid cells regulates development of pulmonary hypertension associated with pulmonary fibrosis and hypoxia.
    Am J Physiol Lung Cell Mol Physiol. 2019 Jul 31. doi: 10.1152/ajplung.00156.2019
    PubMed     Abstract available


  42. LACHANT D, Meoli DF, Haight D, Staicu S, et al
    Combination Therapy Improves Vascular Volume in Female Rats with Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019 Jul 19. doi: 10.1152/ajplung.00450.2018
    PubMed     Abstract available


  43. CHANG CJ, Hsu HC, Ho WJ, Chang GJ, et al
    Cathepsin S promotes the development of pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019;317:L1-L13.
    PubMed     Abstract available


    June 2019
  44. HAO R, Song Y, Li R, Wu Y, et al
    MLN4924 protects against interleukin-17A-induced pulmonary inflammation by disrupting ACT1-mediated signaling.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L1070-L1080.
    PubMed     Abstract available


  45. KIPFMUELLER F, Heindel K, Geipel A, Berg C, et al
    Expression of soluble receptor for advanced glycation end products is associated with disease severity in congenital diaphragmatic hernia.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L1061-L1069.
    PubMed     Abstract available


    May 2019
  46. XIAO R, Zhu L, Su Y, Zhang J, et al
    Monocrotaline pyrrole induces pulmonary endothelial damage through binding to and release from erythrocytes in lung during venous blood reoxygenation.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L798-L809.
    PubMed     Abstract available


  47. HOGAN SE, Rodriguez Salazar MP, Cheadle J, Glenn R, et al
    Mesenchymal stromal cell-derived exosomes improve mitochondrial health in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L723-L737.
    PubMed     Abstract available


    March 2019
  48. UDJUS C, Cero FT, Halvorsen B, Behmen D, et al
    Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25. doi: 10.1152/ajplung.00322.2018
    PubMed     Abstract available


  49. NOVELLI EM, Little-Ihrig L, Knupp HE, Rogers NM, et al
    Vascular TSP1-CD47 Signaling Promotes Sickle Cell-Associated Arterial Vasculopathy and Pulmonary Hypertension in Mice.
    Am J Physiol Lung Cell Mol Physiol. 2019 Mar 20. doi: 10.1152/ajplung.00302.2018
    PubMed     Abstract available


  50. HEWES JL, Bauer NN
    Extracellular Vesicles in Pulmonary Hypertension: Lessons from Mesenchymal Stromal Cell-Derived Exosomes.
    Am J Physiol Lung Cell Mol Physiol. 2019 Mar 13. doi: 10.1152/ajplung.00107.2019
    PubMed    


  51. MOURADIAN GC JR, Alvarez-Argote S, Gorzek R, Thuku G, et al
    Acute and chronic changes in the control of breathing in a rat model of bronchopulmonary dysplasia.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L506-L518.
    PubMed     Abstract available


  52. QUATREDENIERS M, Nakhleh MK, Dumas SJ, Courboulin A, et al
    Functional interaction between PDGFbeta and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L445-L455.
    PubMed     Abstract available


    February 2019
  53. BARMAN SA, Li X, Haigh S, Kondrikov D, et al
    Galectin-3 is Expressed in Vascular Smooth Muscle Cells and Promotes Pulmonary Hypertension through changes in Proliferation, Apoptosis and Fibrosis.
    Am J Physiol Lung Cell Mol Physiol. 2019 Feb 6. doi: 10.1152/ajplung.00186.2018.
    PubMed     Abstract available


    January 2019
  54. ZHANG R, Su H, Ma X, Xu X, et al
    MiRNA let-7b promotes the development of hypoxic pulmonary hypertension by targeting ACE2.
    Am J Physiol Lung Cell Mol Physiol. 2019 Jan 10. doi: 10.1152/ajplung.00387.2018
    PubMed     Abstract available


  55. RAFIKOV R, McBride ML, Zemskova M, Kurdyukov S, et al
    INOSITOL MONOPHOSPHATASE 1 (IMPA1) AS A NOVEL INTERACTING PARTNER OF RAGE IN PULMONARY HYPERTENSION.
    Am J Physiol Lung Cell Mol Physiol. 2019 Jan 3. doi: 10.1152/ajplung.00393.2018.
    PubMed     Abstract available


  56. RASHID J, Nozik-Grayck E, McMurtry IF, Stenmark KR, et al
    Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L119-L130.
    PubMed     Abstract available


    October 2018
  57. WANG Z, Yang K, Zheng Q, Zhang C, et al
    Divergent Changes of p53 in Pulmonary Arterial Endothelial and Smooth Muscle Cells Involved in the Development of Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2018 Oct 25. doi: 10.1152/ajplung.00538.2017
    PubMed     Abstract available


    September 2018
  58. STAM K, van Duin RWB, Uitterdijk A, Krabbendam-Peters I, et al
    Pulmonary microvascular remodeling in chronic thrombo-embolic pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2018 Sep 27. doi: 10.1152/ajplung.00043.2018
    PubMed     Abstract available


  59. SIKARWAR AS, Hinton M, Santhosh KT, Dhanaraj P, et al
    Hypoxia Inhibits Adenylyl Cyclase Catalytic Activity in a Porcine Model of Persistent Pulmonary Hypertension of the Newborn.
    Am J Physiol Lung Cell Mol Physiol. 2018 Sep 20. doi: 10.1152/ajplung.00130.2018
    PubMed     Abstract available


  60. RATSEP MT, Moore SD, Jafri S, Mitchell M, et al
    Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency.
    Am J Physiol Lung Cell Mol Physiol. 2018 Sep 20. doi: 10.1152/ajplung.00477.2017
    PubMed     Abstract available


    August 2018
  61. LA FRANO M, Fahrmann J, Grapov D, Pedersen T, et al
    Umbilical Cord Blood Metabolomics Reveal Distinct Signatures of Dyslipidemia Prior to Bronchopulmonary Dysplasia and Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2018 Aug 16. doi: 10.1152/ajplung.00283.2017
    PubMed     Abstract available


  62. JANKOV RP, Daniel KL, Iny S, Kantores C, et al
    Sodium nitrite augments lung S-nitrosylation and reverses chronic hypoxic pulmonary hypertension in juvenile rats.
    Am J Physiol Lung Cell Mol Physiol. 2018 Aug 9. doi: 10.1152/ajplung.00184.2018.
    PubMed     Abstract available


    July 2018
  63. SHRESTHA AK, Gopal VYN, Menon R, Hagan JL, et al
    Lung Omics Signatures in a Bronchopulmonary Dysplasia and Pulmonary Hypertension-like Murine Model.
    Am J Physiol Lung Cell Mol Physiol. 2018 Jul 26. doi: 10.1152/ajplung.00183.2018
    PubMed     Abstract available


  64. SHEN YS, Goncharova EA
    TWISTed HIF: Re-visiting Smooth Muscle HIF-1alpha Signaling in Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2018 Jul 5. doi: 10.1152/ajplung.00285.2018.
    PubMed    


    May 2018
  65. CHAUDHARY KR, Stewart DJ
    Go with the (back) flow: what can retrograde perfusion teach us about arterial remodeling in pulmonary arterial hypertension?
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L797-L798.
    PubMed    


  66. YADAV VR, Song T, Mei L, Joseph L, et al
    PLCgamma1-PKCepsilon-IP3R1 signaling plays an important role in hypoxia-induced calcium response in pulmonary artery smooth muscle cells.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L724-L735.
    PubMed     Abstract available


  67. SURESH K, Servinsky L, Jiang H, Bigham Z, et al
    Reactive oxygen species induced Ca(2+) influx via TRPV4 and microvascular endothelial dysfunction in the SU5416/hypoxia model of pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L893-L907.
    PubMed     Abstract available


  68. LU Q, Gottlieb E, Rounds S
    Effects of cigarette smoke on pulmonary endothelial cells.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L743-L756.
    PubMed     Abstract available


  69. ZHOU C, Crockett ES, Batten L, McMurtry IF, et al
    Pulmonary vascular dysfunction secondary to pulmonary arterial hypertension: insights gained through retrograde perfusion.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L835-L845.
    PubMed     Abstract available


  70. YEE M, Cohen ED, Domm W, Porter GA Jr, et al
    Neonatal hyperoxia depletes pulmonary vein cardiomyocytes in adult mice via mitochondrial oxidation.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L846-L859.
    PubMed     Abstract available


    April 2018
  71. ZHANG C, Ma C, Yao H, Zhang L, et al
    12-Lipoxygenase and 12-hydroxyeicosatetraenoic acid regulate hypoxic angiogenesis and survival of pulmonary artery endothelial cells via PI3K/Akt pathway.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L606-L616.
    PubMed     Abstract available


    March 2018
  72. ZHONG Y, Catheline D, Houeijeh A, Sharma D, et al
    Maternal PUFA omega-3 supplementation prevents hyperoxia-induced pulmonary hypertension in the offspring.
    Am J Physiol Lung Cell Mol Physiol. 2018 Mar 29. doi: 10.1152/ajplung.00527.2017
    PubMed     Abstract available


  73. SYSOL JR, Chen J, Singla S, Zhao S, et al
    Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L461-L472.
    PubMed     Abstract available


  74. LI HH, Hsu HH, Chang GJ, Chen IC, et al
    Prostanoid EP4 agonist L-902,688 activates PPARgamma and attenuates pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L349-L359.
    PubMed     Abstract available


    February 2018
  75. HENSLEY MK, Levine A, Gladwin MT, Lai YC, et al
    Emerging Therapeutics in Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1. doi: 10.1152/ajplung.00259.2017.
    PubMed     Abstract available


    January 2018
  76. MARSHALL JD, Bazan I, Zhang Y, Fares WH, et al
    Mitochondrial dysfunction and pulmonary hypertension: Cause, Effect or Both.
    Am J Physiol Lung Cell Mol Physiol. 2018 Jan 18. doi: 10.1152/ajplung.00331.2017
    PubMed     Abstract available


  77. DELANEY C, Sherlock L, Fisher S, Maltzahn JK, et al
    Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice.
    Am J Physiol Lung Cell Mol Physiol. 2018 Jan 18. doi: 10.1152/ajplung.00215.2017
    PubMed     Abstract available


  78. BLISSENBACH B, Nakas CT, Kronke M, Geiser T, et al
    Hypoxia-induced changes in plasma micro-RNAs correlate with pulmonary artery pressure at high altitude.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L157-L164.
    PubMed     Abstract available


  79. SUZUKI T, Carrier EJ, Talati MH, Rathinasabapathy A, et al
    Isolation and characterization of endothelial-to-mesenchymal transition cells in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L118-L126.
    PubMed     Abstract available


  80. BARRETO ORTIZ S, Hori D, Nomura Y, Yun X, et al
    Opsin 3 and 4 mediate light-induced pulmonary vasorelaxation that is potentiated by G protein-coupled receptor kinase 2 inhibition.
    Am J Physiol Lung Cell Mol Physiol. 2018;314:L93-L106.
    PubMed     Abstract available


    December 2017
  81. TANNENBERG P, Chang YT, Muhl L, Lavina B, et al
    Extracellular Retention of PDGF-B Directs Vascular Remodeling in Mouse Hypoxia-induced Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2017 Dec 6:ajplung.00054.2017.
    PubMed     Abstract available


    November 2017
  82. ZHANG YX, Li JF, Yang YH, Zhai ZG, et al
    Renin-angiotensin system regulates pulmonary arterial smooth muscle cell migration in chronic thromboembolic pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2017 Nov 9:ajplung.00515.2016.
    PubMed     Abstract available


  83. FRUMP AL, Bonnet S, de Jesus Perez VA, Lahm T, et al
    The emerging role of angiogenesis in adaptive and maladaptive right ventricular remodeling in pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2017 Nov 2:ajplung.00374.2017.
    PubMed     Abstract available


  84. CHEN R, Zhong W, Shao C, Liu P, et al
    Docosahexaenoic acid inhibits monocrotaline-induced pulmonary hypertension via attenuating endoplasmic reticulum stress and inflammation.
    Am J Physiol Lung Cell Mol Physiol. 2017 Nov 2:ajplung.00046.2017.
    PubMed     Abstract available


  85. KATO F, Sakao S, Takeuchi T, Suzuki T, et al
    Endothelial cell-related autophagic pathways in Sugen/hypoxia-exposed pulmonary arterial hypertensive rats.
    Am J Physiol Lung Cell Mol Physiol. 2017;313:L899-L915.
    PubMed     Abstract available


  86. YUN X, Jiang H, Lai N, Wang J, et al
    Aquaporin 1-mediated changes in pulmonary arterial smooth muscle cell migration and proliferation involve beta-catenin.
    Am J Physiol Lung Cell Mol Physiol. 2017;313:L889-L898.
    PubMed     Abstract available


    October 2017
  87. TANG H, Babicheva A, McDermott KM, Gu Y, et al
    Endothelial HIF-2alpha Contributes to Severe Pulmonary Hypertension by Inducing Endothelial-to-Mesenchymal Transition.
    Am J Physiol Lung Cell Mol Physiol. 2017 Oct 26:ajplung.00096.2017.
    PubMed     Abstract available


    September 2017
  88. DIEFFENBACH PB, Haeger CM, Coronata AMF, Choi KM, et al
    Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2.
    Am J Physiol Lung Cell Mol Physiol. 2017;313:L628-L647.
    PubMed     Abstract available


    August 2017
  89. SCHREIBER C, Eilenberg MS, Kiss A, Bergmeister H, et al
    PRESERVED RIGHT VENTRICULAR INTEGRITY IN A NEW TELEMETRIC RAT MODEL OF SEVERE PULMONARY HYPERTENSION.
    Am J Physiol Lung Cell Mol Physiol. 2017 Aug 10:ajplung.00278.2017.
    PubMed     Abstract available


  90. PENUMATSA KC, Toksoz D, Warburton RR, Kharnaf M, et al
    Transglutaminase 2 in Pulmonary and Cardiac Tissue Remodeling in Experimental Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2017 Aug 3:ajplung.00170.2017.
    PubMed     Abstract available


  91. GREEN DE, Murphy TC, Kang BY, Bedi B, et al
    Peroxisome proliferator-activated receptor-gamma enhances human pulmonary artery smooth muscle cell apoptosis through microRNA-21 and programmed cell death 4.
    Am J Physiol Lung Cell Mol Physiol. 2017;313:L371-L383.
    PubMed     Abstract available


  92. ORCHOLSKI ME, Khurshudyan A, Shamskhou EA, Yuan K, et al
    Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2017;313:L252-L266.
    PubMed     Abstract available


    July 2017
  93. NAGY BM, Nagaraj C, Meinitzer A, Sharma N, et al
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    May 2016
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