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Periodontology

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Articles published in Clin Oral Investig
Retrieve available abstracts of 357 articles:
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Single Articles

January 2026

GUO R, Ma N, Shi T, Wang Y, et al
Fully automatic AI diagnosis of alveolar bone defect in anterior teeth on CBCT images.
Clin Oral Investig. 2026;30:60.
PubMed Abstract available

ORUC AH, Babayigit O
Salivary asprosin, IL-39, IL-40, and IL-1beta levels in diabetic patients with periodontitis: A cross-sectional analysis.
Clin Oral Investig. 2026;30:52.
PubMed Abstract available

NUMAZAKI K, Tamahara T, Komiyama T, Numazaki T, et al
Association of anterior crossbite and open bite with the number of remaining teeth: A cross-sectional study from the Tohoku medical megabank cohort.
Clin Oral Investig. 2026;30:43.
PubMed Abstract available

LIU X, Zou Y, Jin C, Wang Y, et al
Viral infections are associated with apical periodontitis: A meta-analysis of prevalence, clinical symptoms, and lesion sizes across 31 clinical studies.
Clin Oral Investig. 2026;30:37.
PubMed Abstract available

December 2025

ZHENG Y, Wang D, Yang D, Jiang T, et al
Exploring hypoxia- and cuproptosis-related biomarkers in periodontitis based on transcriptome and single-cell analysis.
Clin Oral Investig. 2025;30:33.
PubMed Abstract available

PASALI C, Emingil G, Yilmaz B, Kantarci A, et al
Three-session non-surgical therapy stabilizes microbiological and biochemical responses in patients with stage III/IV grade C periodontitis: a randomized clinical trial.
Clin Oral Investig. 2025;30:29.
PubMed Abstract available

BABURCAN CT, Keceli HG, Ozbay Cetiner D, Corekci AU, et al
Impact of partial restoration margin level in combination with connective tissue graft on the treatment of single RT1 gingival recessions associated with non-carious cervical lesions: a 1-year randomized parallel-group trial.
Clin Oral Investig. 2025;30:16.
PubMed Abstract available

SHI R, Jamieson L, Nath S
Does non-surgical periodontal therapy improve biomarkers associated with cardiovascular disease? An umbrella review.
Clin Oral Investig. 2025;30:10.
PubMed Abstract available

MALUF CV, Hirata R, Lourenco EJV, Pegoraro LF, et al
Digital quantitative analysis of noncarious cervical Lesions, occlusal tooth Wear, and gingival recession: results from a 25-Year clinical Follow-Up study.
Clin Oral Investig. 2025;30:5.
PubMed Abstract available

AAL MA, Kern M, N Naiem S, Abdel Wahab Radi I, et al
Marginal bone loss in single implant-retained mandibular overdentures using two different healing protocols and two different types of attachments: A 2-year follow-up of a randomized controlled trial.
Clin Oral Investig. 2025;29:603.
PubMed Abstract available

HU KF, Yeh JL, Lin YC, Liu PF, et al
The correlation between body mass index and the effectiveness of non-surgical periodontal treatment in Taiwan population.
Clin Oral Investig. 2025;29:596.
PubMed Abstract available

November 2025

PREMKUMAR S, Appukuttan D, Kumar JR, Venkadassalapathy S, et al
Comparative evaluation of ferroptosis markers NCOA4, ACSL4, and Nrf2 in periodontitis with and without type 2 diabetes mellitus: a case-control study.
Clin Oral Investig. 2025;29:591.
PubMed Abstract available

DA ROCHA COSTA COELHO T, Machion Shaddox L, Nunes de Carvalho G, Damiao Costa D, et al
The association between gingivitis and SARS-CoV-2 colonization of subgingival biofilm in COVID-19 individuals: a cross-sectional preliminary study.
Clin Oral Investig. 2025;29:590.
PubMed Abstract available

ROMANO F, Baima G, Llerena-Velasquez M, Siccardi L, et al
Impact of lifestyle behaviors on clinical outcomes of steps 1 and 2 of periodontal therapy in stage iii-iv periodontitis: a cohort study.
Clin Oral Investig. 2025;29:584.
PubMed Abstract available

ELHADDAD SA, Alasfar AA, El-Shaglabow SA, Elgendy EA, et al
Local delivery of hyaluronan and minocycline as an adjunct to subgingival instrumentation in the treatment of stage II grade B diabetic periodontitis: a randomized split-mouth clinical and microbiological study.
Clin Oral Investig. 2025;29:578.
PubMed Abstract available

MOTA ME, Alves FA, Franco JB, Filho JS, et al
Systemic implications of endodontic and periodontal infections in hematopoietic stem cell transplantation: a systematic review.
Clin Oral Investig. 2025;29:576.
PubMed Abstract available

YANG Y, Peng Y, Liu L, Min Z, et al
Surgical interventions for endodontic-periodontal lesions: A Systematic Review without Meta-analysis (SWiM).
Clin Oral Investig. 2025;29:574.
PubMed Abstract available

SAITO N, Mikami R, Mizutani K, Aoyama N, et al
Income-related inequalities in the association of obesity and periodontal disease: a register-based cross-sectional analysis in the Tokyo metropolitan districts.
Clin Oral Investig. 2025;29:570.
PubMed Abstract available

BLASI A, Mauriello L, Iorio-Siciliano V, Pezzella V, et al
Long term clinical results of intrabony defects treated with periodontal regeneration. A retrospective analysis based on composite outcome measure.
Clin Oral Investig. 2025;29:568.
PubMed Abstract available

LIU J, Zhou Y, Zhang L, Wang S, et al
Effects of daily home-use water flossing as an adjunct to non-surgical periodontal therapy in the treatment of stage I-II periodontitis: a 6-month randomized controlled trial.
Clin Oral Investig. 2025;29:567.
PubMed Abstract available

KAVYA GL, Kumar KA, Penmetsa GS, Bhupathi A, et al
"Clinical and radiological evaluation of periodontal intrabony defects treated with DFDBA and 1% melatonin gel and its effect on RANKL and OPG in gingival crevicularfluid - a randomized controlled trial".
Clin Oral Investig. 2025;29:557.
PubMed Abstract available

OLCZAK-KOWALCZYK D, Studnicki M, Twetman S, Turska-Szybka A, et al
Association between vitamin D supplementation and the prevalence of dental caries and gingivitis in children. A cross-sectional study.
Clin Oral Investig. 2025;29:556.
PubMed Abstract available

KABOOSAYA B, Arunjaroensuk S, Pimkhaokham A
Influence of maximum tongue strength on implant stability and marginal bone loss in posterior mandibular implants: a preliminary prospective study.
Clin Oral Investig. 2025;29:554.
PubMed Abstract available

WATTANAWONGWAN W, Krasaesin A, Khieota T, Thongchotchat V, et al
Effects of chlorhexidine and a polyherbal mouthwash on the oral microbiome and user satisfaction: a randomized controlled trial.
Clin Oral Investig. 2025;29:555.
PubMed Abstract available

VAKAKI C, Fragkioudakis I, Patila T, Sakellari D, et al
Regular home use of dual-light photodynamic therapy as an adjunct to non-surgical periodontal treatment in smokers: a single-center randomized controlled clinical trial.
Clin Oral Investig. 2025;29:553.
PubMed Abstract available

JIANG L, Li S, Reissmann DR, Hu S, et al
Identifying subtypes of functional dentition in older adults: a population-based regression and latent class analysis.
Clin Oral Investig. 2025;29:549.
PubMed Abstract available

October 2025

CHEN K, Ren X, Du R, Lei L, et al
The site-specific subgingival microbiome across periodontal conditions and its relationship with clinical parameters.
Clin Oral Investig. 2025;29:541.
PubMed Abstract available

HELAL MH, Ali AN, Hamdy Y, Shoukheba MYM, et al
beta-tricalcium phosphate/gelatin composite scaffolds incorporated with gentamycin-loaded chitosan microspheres for periodontal regeneration in class II furcation defects in dogs.
Clin Oral Investig. 2025;29:540.
PubMed Abstract available

BIRADAR V, Mody D, Kolte AP, Lathiya V, et al
Comparative evaluation of demineralized freeze-dried bone allograft with and without doxycycline hyclate loaded proniosomal gel in the treatment of class II furcation defects: a randomized controlled trial.
Clin Oral Investig. 2025;29:520.
PubMed Abstract available

ZHANG L, Ding Y, Zhang B, Hu X, et al
Analysis of the correlation between glycemic variability indices and disease severity as well as inflammatory status in patients with type 2 diabetes mellitus and periodontitis.
Clin Oral Investig. 2025;29:508.
PubMed Abstract available

HE H, Zhu J, Li C, Shen Q, et al
Analysis of subgingival microbial community structure in MAFLD patients with periodontitis.
Clin Oral Investig. 2025;29:504.
PubMed Abstract available

THOMAS JT, Joseph B, Raisanen IT, Anil S, et al
Diagnostic accuracy of aMMP-8 levels in oral biofluids for monitoring periodontitis in patients with metabolic syndrome.
Clin Oral Investig. 2025;29:500.
PubMed Abstract available

WANG S, Jie B
AIM2 and IFI16 as nucleic acid sensors in Periodontitis-Driven systemic inflammation: emerging evidence and therapeutic implications.
Clin Oral Investig. 2025;29:486.
PubMed Abstract available

September 2025

TAYMAN MA, Kizilgun M
Effect of nonsurgical periodontal treatment on NLRP3, Nrf2, Caspase-1, interleukin-1B, interleukin-18 in gingival crevicular fluid of severe periodontitis.
Clin Oral Investig. 2025;29:474.
PubMed Abstract available

GORGULU NG, Gungormek HS, Kalkan Y, Dogan B, et al
Evaluation of chemerin, fetuin-A, interleukin-34, and interleukin-13 levels following periodontal treatment in diabetes mellitus.
Clin Oral Investig. 2025;29:448.
PubMed Abstract available

MAN Y, Fan C, Qu H, Wang C, et al
Progesterone-induced activation of progesterone receptor alleviates alveolar bone resorption and inflammatory response in periodontitis.
Clin Oral Investig. 2025;29:446.
PubMed Abstract available

PAOLANTONIO M, De Ninis P, Santamaria P, Balice G, et al
Clinical comparison of two surgical techniques in obtaining complete root coverage of single RT1 gingival recessions.
Clin Oral Investig. 2025;29:444.
PubMed Abstract available

ZHU L, Liang S, Yang Y, Su Z, et al
Association between vitamin K intake and periodontitis in American elderly population: a cross-sectional analysis of NHANES data.
Clin Oral Investig. 2025;29:442.
PubMed Abstract available

SELVARAJ T, Mahendra J, Ravi N, Dave PH, et al
Estimation of salivary protectin D1 in periodontitis patients with metabolic syndrome following non-surgical periodontal therapy.
Clin Oral Investig. 2025;29:441.
PubMed Abstract available

WARWAS FB, Thol F, Sieber MA, Spuck N, et al
Next-generation sequencing improves pathogen identification in odontogenic abscesses, could this affect clinical outcomes?
Clin Oral Investig. 2025;29:430.
PubMed Abstract available

YADAV D, Batra P, Talwar A, Sonar S, et al
A comparative assessment of orthodontically induced root resorption and alveolar bone changes in adolescent orthodontic patients undergoing Micro-Osteoperforations assisted canine retraction: A Split-Mouth randomized controlled trial.
Clin Oral Investig. 2025;29:429.
PubMed Abstract available

August 2025

LUCCHESI VH, Giorgetti APO, Correa MG, Pecorari VGA, et al
Impact of systemic resveratrol on non-surgical periodontal treatment of smokers: A 12-month randomized clinical trial.
Clin Oral Investig. 2025;29:428.
PubMed Abstract available

HUI S, Hong Y, Chen S, Bao Y, et al
Efficacy of maxillary occlusal splints on mobile posterior teeth in patients with stage III or IV periodontitis during steps 1 and 2 of periodontal therapy: a randomized parallel-controlled clinical trial.
Clin Oral Investig. 2025;29:425.
PubMed Abstract available

MENSI M, Scotti E, Marchetti S, Sordillo A, et al
Clinical and microbiological effectiveness of limosilactobacillus reuteri in supportive periodontal therapy: randomized clinical trial.
Clin Oral Investig. 2025;29:422.
PubMed Abstract available

LAZARIDI I, Choong E, Mercier T, Decosterd LA, et al
A comparison between venous blood sampling and capillary volumetric absorptive microsampling for antibiotics levels monitoring in individuals with and without periodontal disease.
Clin Oral Investig. 2025;29:420.
PubMed Abstract available

PEDROSA ME, Martin V, Fernandes MH, Gomes PS, et al
Gingipain inhibitors as an innovative therapy for periodontal and associated-systemic diseases: a systematic review.
Clin Oral Investig. 2025;29:418.
PubMed Abstract available

LIU Y, Liu Y, Yin T, He M, et al
Association of tooth loss with circadian syndrome in US adults: the mediated role of systemic inflammation.
Clin Oral Investig. 2025;29:416.
PubMed Abstract available

GUNPINAR S, Gundogdu Ezer U, Gonulay S, Tasmektepligil AA, et al
Effects of periodontal disease prediction system on oral hygiene motivation in patients with periodontitis: a prospective randomized controlled clinical study.
Clin Oral Investig. 2025;29:412.
PubMed Abstract available

PSG P, Sanjeev K, Subramanian S, Thanigaimalai A, et al
Clinical, radiographic and molecular efficacy of LLLT along with minimally invasive flaps in regeneration of periodontal intrabony defects: a randomized controlled clinical trial.
Clin Oral Investig. 2025;29:404.
PubMed Abstract available

YASAR CC, Ates S, Aksoy T, Yabaci Tak A, et al
Annexin A1 levels in polycystic ovary syndrome: impact of professional mechanical plaque removal.
Clin Oral Investig. 2025;29:406.
PubMed Abstract available

July 2025

MATEA T, Matea B, Martina Z, Anbo D, et al
Effect of chlorhexidine mouthwash on subgingival bacterial endotoxin activity and periodontal status during treatment with metal and non-metal fixed orthodontic appliance: a randomized controlled trial.
Clin Oral Investig. 2025;29:387.
PubMed Abstract available

SENER A, Dede FO, Avci B, Balli U, et al
Effect of 0.8% Hyaluronic Acid-Based Gel on Clinical and Biomolecular parameters in the surgical periodontal treatment of Stage III periodontitis patients: a randomized, split-mouth clinical trial.
Clin Oral Investig. 2025;29:381.
PubMed Abstract available

ELKERSH NM, Hassan MG, Zakaria O
Pseudo-color enhancement of CBCT images as a diagnostic tool for radicular cysts and periapical granulomas: A clinical feasibility study.
Clin Oral Investig. 2025;29:371.
PubMed Abstract available

June 2025

AHMAD P, Estrin N, Farshidfar N, Zhang Y, et al
Mechanistic insights into periodontal ligament stem cell-derived exosomes in tissue regeneration.
Clin Oral Investig. 2025;29:357.
PubMed Abstract available

KADAYIF A, Tasci OE, Karaduman B
Effects of non-surgical periodontal therapy on gingival crevicular fluid CTRP-1, TNF-alpha, and IL-10 levels.
Clin Oral Investig. 2025;29:345.
PubMed Abstract available

DE OLIVEIRA ALVES R, Garcia Orsi C, Alves Oliveira J, de Rezende Barbosa GL, et al
Adjuvant effects of injectable platelet-rich fibrin (i-PRF) in the non-surgical periodontal therapy: a split-mouth randomized controlled clinical trial.
Clin Oral Investig. 2025;29:341.
PubMed Abstract available

VAN GENNIP LLA, Bulthuis MS, Thomas RZ, Bronkhorst EM, et al
The effect of conditioning regimen intensity on periodontal health in haematopoietic cell transplantation recipients: a 5-year multicentre prospective cohort study.
Clin Oral Investig. 2025;29:338.
PubMed Abstract available

SIGUSCH B, Kranz S, Heyder M, Weber A, et al
Peridontopathogenic key species in correlation to the current classification system.
Clin Oral Investig. 2025;29:339.
PubMed Abstract available

MANDIL O, Alrmali A, Kalani K, Ray B, et al
Effect of single-visit full-mouth non-surgical therapy and risk factor analysis on long-term periodontal treatment outcomes: aretrospective study.
Clin Oral Investig. 2025;29:333.
PubMed Abstract available

YURDAKURBAN E, Bayirli AB, Uytun M, Suceken O, et al
Automated periodontal assessment in orthodontic patients: a dual CNN framework.
Clin Oral Investig. 2025;29:328.
PubMed Abstract available

May 2025

GOMES-MOURA AP, Araujo LDC, Lucisano MP, Lima RB, et al
Probiotic-based irrigation solution reduces neutrophil extracellular trap formation and stimulates CRAMP antimicrobial peptide expression in rat teeth with induced periapical lesions.
Clin Oral Investig. 2025;29:317.
PubMed Abstract available

SIMONELLI A, Farina R, Minenna L, Scapoli C, et al
Factors influencing pocket closure in surgically-treated intraosseous defects. A retrospective analysis.
Clin Oral Investig. 2025;29:316.
PubMed Abstract available

BORGES GA, Borges MHR, Dini C, Marcello-Machado RM, et al
Prognosis of removable complete dentures considering the level of mandibular residual ridge resorption: a systematic review and meta-analysis.
Clin Oral Investig. 2025;29:307.
PubMed Abstract available

XIONG Y, Liu B, Li W, Chen J, et al
Causal association between female reproductive factors and periodontitis: evidence from Mendelian randomization study.
Clin Oral Investig. 2025;29:293.
PubMed Abstract available

QUINTAS-HIJOS J, Perez-Pevida E
Influence of intermediate abutment height and timing of placement on marginal bone loss in single implant-supported crowns: a 12-month follow-up randomized clinical trial.
Clin Oral Investig. 2025;29:291.
PubMed Abstract available

DIN F, Kabalak MO, Yilmaz BT, Baris E, et al
Efficacy of different gingival graft de-epithelialization methods: A parallel-group randomized clinical trial.
Clin Oral Investig. 2025;29:289.
PubMed Abstract available

BRITOS M, Hernandez M, Fernandez A, Pellegrini E, et al
Bacterial translocation signatures and subgingival microbiome in individuals with periodontitis.
Clin Oral Investig. 2025;29:288.
PubMed Abstract available

AL-AGOOZ A, Ata F, Saleh W, Elmeadawy S, et al
Clinical and radiographic evaluation of melatonin and chitosan loaded nanoparticles in the treatment of periodontal intra-bony defects: A Randomized controlled clinical trial.
Clin Oral Investig. 2025;29:280.
PubMed Abstract available

April 2025

FU L, Chang JJ, Al Hezaimi K, Sasi L, et al
In vivo periodontal ultrasound imaging via a hockey-stick transducer and comparison to periodontal probing: a proof-of-concept study.
Clin Oral Investig. 2025;29:275.
PubMed Abstract available

DERVISBEGOVIC S, Lettner S, Tur D, Laky M, et al
Adjunctive low-level laser therapy in periodontal treatment - A randomized clinical split-mouth trial.
Clin Oral Investig. 2025;29:273.
PubMed Abstract available

JUNG J, Lee J, Lee S, Koo KT, et al
The impact of selcopintide on periodontal regeneration in a class II furcation defect model: a radiographic and histomorphometric analysis.
Clin Oral Investig. 2025;29:265.
PubMed Abstract available

MUNDT T, Jaghsi AA, Heinemann F, Schwahn C, et al
Mini-implant placement under existing removable partial dentures decreased the mobility of remaining teeth in a randomized controlled 3-year clinical trial.
Clin Oral Investig. 2025;29:266.
PubMed Abstract available

FERNANDEZ A, Bendek MJ, Bordagaray MJ, Ramirez V, et al
Exploring the regulatory roles of MicroRNAs on NF- KappaB target genes in individuals with apical periodontitis.
Clin Oral Investig. 2025;29:251.
PubMed Abstract available

SHARMA G, Tanwar N, Tewari S, Arora R, et al
Comparative evaluation of efficacy of volume stable collagen matrix in interdental papilla reconstruction as compared to connective tissue graft in maxillary esthetic region: a randomized controlled clinical trial.
Clin Oral Investig. 2025;29:235.
PubMed Abstract available

DE OLIVEIRA ICV, Alencar-Junior HS, Campos HRSS, Rodrigues VP, et al
Influence of antidepressant use on periodontal status: a systematic review and meta-analysis.
Clin Oral Investig. 2025;29:229.
PubMed Abstract available

CHEN X, You X, Chen C, Yang Y, et al
Presumed periodontitis and multimorbidity patterns: a prospective cohort study in the UK Biobank.
Clin Oral Investig. 2025;29:222.
PubMed Abstract available

MA LS, Jia XT, Hu FQ, Zheng YJ, et al
Mechanism of Lycium barbarum in treating periodontitis based on network pharmacology, molecular docking, and experimental validation.
Clin Oral Investig. 2025;29:219.
PubMed Abstract available

March 2025

DE OLIVEIRA ROCHA A, Goebel MC, Cardoso K, Dos Anjos LM, et al
Does the early loss of primary teeth impact the oral health-related quality of life of children? A systematic review and meta-analysis.
Clin Oral Investig. 2025;29:213.
PubMed Abstract available

KANG TG, Kim NY, Lee SM, Chung KH, et al
Atherogenic index of plasma and periodontitis in non-dyslipidemic adults: a nationwide study.
Clin Oral Investig. 2025;29:208.
PubMed Abstract available

YING X, Dai Y, Bai G, Cheng Z, et al
Varying responses to periodontal treatment in different extent of plaque-induced gingivitis: a prospective cohort study.
Clin Oral Investig. 2025;29:204.
PubMed Abstract available

SERDAR CC, Guney Z, Balci N, Altingoz SM, et al
Salivary trimethylamine N-oxide: a novel non-invasive marker for periodontal inflammation.
Clin Oral Investig. 2025;29:206.
PubMed Abstract available

GAO L, Zhu H, Kou Y, Hu H, et al
The effects of beta-TCP and/or xenogeneic bone substitute on alveolar ridge preservation: a randomized clinical trial.
Clin Oral Investig. 2025;29:200.
PubMed Abstract available

CASSIANO LBA, da Silva JPC, Martins AA, Barbosa MT, et al
Evaluation of an artificial intelligence-based model in diagnosing periodontal radiographic bone loss.
Clin Oral Investig. 2025;29:195.
PubMed Abstract available

RODRIGUEZ-A M, Montiel-Company JM, Alpiste-Illueca F, Rodriguez-A L, et al
Comparision of crosslinked hyaluronic acid vs. enamel matrix derivative for periodontal regeneration: an 18-month follow-up randomized clinical trial.
Clin Oral Investig. 2025;29:197.
PubMed Abstract available

LUO B, Xiao J, Yan F, Li Y, et al
Changes in creeping attachment for soft tissue augmentation surgery.
Clin Oral Investig. 2025;29:191.
PubMed Abstract available

SOKOLOWSKI A, Lorenzoni M, Steyer E, Marschner F, et al
In-patient comparison of marginal bone loss after 4 months in immediately loaded, submucosal, and transmucosal dental implants using 3D scanning: a prospective clinical trial.
Clin Oral Investig. 2025;29:186.
PubMed Abstract available

PARDINAS LOPEZ S, Garcia-Caro ME, Vallejo JA, Aja-Macaya P, et al
Anti-inflammatory and antimicrobial efficacy of coconut oil for periodontal pathogens: a triple-blind randomized clinical trial.
Clin Oral Investig. 2025;29:182.
PubMed Abstract available

ZAMPARINI F, Spinelli A, Lenzi J, Peters OA, et al
Retreatment or replacement of previous endodontically treated premolars with recurrent apical periodontitis? An 8-year historical cohort study.
Clin Oral Investig. 2025;29:181.
PubMed Abstract available

KREDIG C, Peuckert E, Schmidtmann I, Drechsler T, et al
Oral health in adolescents: periodontal inflammatory biomarkers during orthodontic clear aligner therapy.
Clin Oral Investig. 2025;29:168.
PubMed Abstract available

MOHAMMADI M, Baker E, Chrcanovic BR
Clinical and radiographic outcomes of mini-implant-retained maxillary and mandibular overdentures: a systematic review and meta-analysis.
Clin Oral Investig. 2025;29:164.
PubMed Abstract available

SILVA CMPC, Massoni VV, Araujo LDC, Lima RB, et al
Correlation between REDOX enzymes and NET markers expression during the development of periapical lesions in mice.
Clin Oral Investig. 2025;29:166.
PubMed Abstract available

February 2025

JI C, Chen Y, Si M, Chen X, et al
The impact of biocorrosion and titanium ions release on peri-implantitis.
Clin Oral Investig. 2025;29:155.
PubMed Abstract available

CUOZZO A, Blasi A, Canfora F, Iorio-Siciliano V, et al
Tissue autofluorescence system as an aid for Dental Hygienist to screening oral mucosa alterations during supportive periodontal care. An observational single-arm study.
Clin Oral Investig. 2025;29:144.
PubMed Abstract available

HASHIM D, Courvoisier D, Cionca N
A randomised clinical trial comparing a surgical approach for treatment of peri-implantitis to non-surgical debridement with adjunctive diode laser therapy.
Clin Oral Investig. 2025;29:142.
PubMed Abstract available

SAGLAM E, Toraman A, Savran L, Saglam M, et al
Meteorin-like levels of oral fluids in periodontal health and diseases: a comparative cross-sectional study.
Clin Oral Investig. 2025;29:137.
PubMed Abstract available

GAO C, Iles MM, Bishop DT, Larvin H, et al
Genetic risk factors for periodontitis: a genome-wide association study using UK Biobank data.
Clin Oral Investig. 2025;29:129.
PubMed Abstract available

YANG L, Wang L, Zheng YB, Liu Y, et al
Causal relationship between periodontitis and prostate diseases: a bidirectional Mendelian randomization study.
Clin Oral Investig. 2025;29:127.
PubMed Abstract available

XU Q, Cao G, Huang S, Dai D, et al
Peripheral blood immune cell levels differ with the stage and grade of periodontitis in systemically healthy individuals.
Clin Oral Investig. 2025;29:125.
PubMed Abstract available

COSTA R, Rios-Carrasco B, Lopez-Jarana P, Cabral C, et al
Periodontal status and risk factors in patients with type 1 diabetes mellitus.
Clin Oral Investig. 2025;29:113.
PubMed Abstract available

January 2025

KETENCI CAY F, Yesil C, Cay O, Yilmaz BG, et al
DeepLabv3 + method for detecting and segmenting apical lesions on panoramic radiography.
Clin Oral Investig. 2025;29:101.
PubMed Abstract available

BUTI J, Ronca F, Burgess PW, Gallagher J, et al
Association between periodontitis and physical fitness in law enforcement workers.
Clin Oral Investig. 2025;29:99.
PubMed Abstract available

GORSKI B, Skurska A, Roguljic M, Gelemanovic A, et al
Difficulty score for the treatment of multiple gingival recessions with the Modified Coronally Advanced Tunnel technique: a preliminary reliability study.
Clin Oral Investig. 2025;29:91.
PubMed Abstract available

MARGARYAN V, Aghasyan E, Yessayan L, Khachatryan H, et al
Adjunctive therapea - a promising method in the treatment of periodontal disease.
Clin Oral Investig. 2025;29:78.
PubMed Abstract available

FURUKAWA MV, Oliveira MF, da Silva RA, Maximo PM, et al
Salivary proteomic analysis in patients with type 2 diabetes mellitus and periodontitis.
Clin Oral Investig. 2025;29:77.
PubMed Abstract available

LIPOVEC T, Kapadia N, Antonoglou GN, Lu EMC, et al
Autologous platelet concentrates as adjuncts to non-surgical periodontal therapy: a systematic review and meta-analysis.
Clin Oral Investig. 2025;29:74.
PubMed Abstract available

PETEAN IBF, Gaeta-Araujo H, Mazzi-Chaves JF, Silva-Sousa AC, et al
Clinical and imaging aspects associated with persistent apical periodontitis: subsides for the treatment decision-making process.
Clin Oral Investig. 2025;29:71.
PubMed Abstract available

ZHU Y, Shrestha A
Metabolic syndrome and its effect on immune cells in apical periodontitis- a narrative review.
Clin Oral Investig. 2025;29:67.
PubMed Abstract available

PESCE P, Canullo L, Testori T, Mastroianni A, et al
The clinical effect of bone perforations in periodontal regeneration and alveolar socket preservation: a systematic review with meta-analysis.
Clin Oral Investig. 2025;29:64.
PubMed Abstract available

HEUZEROTH G, Kaufmann ME, Herter-Aeberli I, Schlagenauf U, et al
Weighing up the potential of "superfoods" compounds of green tea or turmeric as adjuncts in comparison to established therapeutical approaches for periodontal disease.
Clin Oral Investig. 2025;29:61.
PubMed Abstract available

LI S, Li S, Meng L, Gao R, et al
Immunopathogenesis and immunotherapy of diabetes-associated periodontitis.
Clin Oral Investig. 2025;29:44.
PubMed Abstract available

FAN RY, Chen JX, Chen LL, Sun WL, et al
Assessing periodontitis risk from specific dietary patterns: a systematic review and meta-analysis.
Clin Oral Investig. 2025;29:43.
PubMed Abstract available

December 2024

WANG Z, Pu R, Zhang J, Wang Y, et al
Association between life's essential 8 and periodontitis: evidence from NHANES 2009-2014.
Clin Oral Investig. 2024;29:37.
PubMed Abstract available

HUANG J, Zhang H, Fan X, Wang Y, et al
Therapeutic potential of farnesoid X receptor agonists for modulating inflammation and periodontal regeneration.
Clin Oral Investig. 2024;29:10.
PubMed Abstract available

OZDEN C, Afacan B, Ilhan HA, Kose T, et al
Oral biofluid levels of Activin-A and interleukin-1beta in stage III periodontitis.
Clin Oral Investig. 2024;29:7.
PubMed Abstract available

BARBOZA EP, Panariello B
Letter to the editor in response to "Microbial colonization in the partially exposed nonabsorbable membrane during alveolar ridge preservation" (Braz et al., clinical oral Investigations, https://doi.org/10.1007/s00784-024-05763-7.).
Clin Oral Investig. 2024;28:685.
PubMed Abstract available

JIANG S, Sheng R, Yuan Q, Yang X, et al
Efficacy of reactive soft tissue for alveolar ridge preservation: a prospective cohort study.
Clin Oral Investig. 2024;28:684.
PubMed Abstract available

HE J, Liu Y, Xu H, Wei X, et al
Insights into the variations in microbial community structure during the development of periodontitis and its pathogenesis.
Clin Oral Investig. 2024;28:675.
PubMed Abstract available

November 2024

AL-KARADSHEH OA, Zabadi SJ, Waleed MF, Al-Abedalla KA, et al
Diagnostic delays of periodontitis and associated factors: a cross-sectional study.
Clin Oral Investig. 2024;28:671.
PubMed Abstract available

SEKER C, Yildiran BM, Haylaz E, Geduk G, et al
Assessment of periodontal dehiscence and fenestration using ultrasonography and cone-beam computed tomography: an in vitro study.
Clin Oral Investig. 2024;28:665.
PubMed Abstract available

AZADI A, Eftekhari-Moghadam P, Atarbashi-Moghadam F, Hazrati P, et al
Adjunctive therapy for root coverage with concentrated growth factor versus platelet-rich fibrin membranes: a systematic review and bayesian network meta-analysis.
Clin Oral Investig. 2024;28:654.
PubMed Abstract available

ARIKAN NS, Hepsenoglu YE, Ersahan S, Ozcelik F, et al
Periradicular repair after single-visit root canal treatment using sonic irrigant activation of teeth with apical periodontitis.
Clin Oral Investig. 2024;28:656.
PubMed Abstract available

STOLF CS, Pereira AGS, Almeida BC, Paz HES, et al
Association of RS1126478 (LTF) with molar-incisor and generalized periodontitis.
Clin Oral Investig. 2024;28:653.
PubMed Abstract available

JOSIC U, Maravic T, Mazzitelli C, Rinaldi L, et al
The clinical and microbiological efficacy of a zinc-citrate/hydroxyapatite/potassium-citrate containing toothpaste: a double-blind randomized controlled clinical trial.
Clin Oral Investig. 2024;28:652.
PubMed Abstract available

SALEH W, Ata F, Nosser NA, Mowafey B, et al
Correlation of serum vitamin D and IL-8 to stages of periodontitis: a case-control analysis.
Clin Oral Investig. 2024;28:645.
PubMed Abstract available

ZHANG H, Liu S, Hao R, Yao J, et al
Comparative evaluation of autologous dental bone powder and deproteinized bovine bone mineral allografts for oral implant bone deficits.
Clin Oral Investig. 2024;28:637.
PubMed Abstract available

SEN DO, Sengul BI, Yarkac FU, Oncu E, et al
Impact of platelet-rich fibrin derivatives on patient morbidity and quality of life in palatal donor sites following free gingival graft surgery: a randomized clinical trial.
Clin Oral Investig. 2024;28:631.
PubMed Abstract available

OUTATZIS A, Nickles K, Petsos H, Eickholz P, et al
Periodontal and peri-implant bleeding on probing in patients undergoing supportive maintenance: a cross-sectional study.
Clin Oral Investig. 2024;28:633.
PubMed Abstract available

LIU Y, Yin T, He M, Fang C, et al
The association of reproductive health factors with periodontitis in 45-80 years old US women from NHANES 2009-2014.
Clin Oral Investig. 2024;28:623.
PubMed Abstract available

October 2024

MATOS YR, de Carvalho Leal I, da Silva ABA, de Oliveira NF, et al
Effect of chloramine T and chlorhexidine in reducing gingivitis in patients admitted to a reference hospital for cardiopulmonary care: a randomized, controlled clinical trial.
Clin Oral Investig. 2024;28:619.
PubMed Abstract available

VIGIL MSA, Gowri V, Ramesh SSS, Praba MSB, et al
ADGRU: Adaptive DenseNet with gated recurrent unit for automatic diagnosis of periodontal bone loss and stage periodontitis with tooth segmentation mechanism.
Clin Oral Investig. 2024;28:614.
PubMed Abstract available

IGLHAUT G, Fretwurst T, Schulte L, Sculean A, et al
Digital workflow to assess gingival recession coverage independently of the cemento-enamel Junction: a prospective clinical study using the modified coronally advanced tunnel technique with porcine dermal matrix.
Clin Oral Investig. 2024;28:613.
PubMed Abstract available

RIEGER S, Walker H, Mittelhamm F, Frisch E, et al
Tooth loss during long-term periodontal therapy in specialized practices - a retrospective cohort study from a periodontal practice-based research network (Perio-PBRN).
Clin Oral Investig. 2024;28:607.
PubMed Abstract available

BASSO A, Salas F, Hernandez M, Fernandez A, et al
Machine learning and deep learning models for the diagnosis of apical periodontitis: a scoping review.
Clin Oral Investig. 2024;28:600.
PubMed Abstract available

JIANG L, Li J, Luo M, Yang Z, et al
Analysis of factors associated with tooth loss in older adults from 1995 to 2015: a population-based cross-sectional survey in Guangdong, China.
Clin Oral Investig. 2024;28:601.
PubMed Abstract available

PEIKERT SA, Metzger S, Kruse AB, Mittelhamm F, et al
The seasonal occurrence of periodontitis - a retrospective cohort study from a practice-based research network.
Clin Oral Investig. 2024;28:596.
PubMed Abstract available

APATZIDOU DA, Violesti A, Konstantinidis A, Bao K, et al
Protein profile at newly restored implants compared to contralateral teeth over 12-months: a pilot study.
Clin Oral Investig. 2024;28:590.
PubMed Abstract available

ABOUSHADI MM, Albelasy EH, Ordinola-Zapata R
Association between endodontic symptoms and root canal microbiota: a systematic review and meta-analysis of bacteroidetes, spirochaetes and fusobacteriales.
Clin Oral Investig. 2024;28:593.
PubMed Abstract available

WANG J, Sun Z, Zhong Y, Ye Y, et al
Hypertensive patients with periodontitis as predictors of cardiovascular and all-cause mortality: a long-term cohort study.
Clin Oral Investig. 2024;28:582.
PubMed Abstract available

IMAMURA K, Yoshida W, Seshima F, Aoki H, et al
Periodontal regenerative therapy using recombinant human fibroblast growth factor (rhFGF)-2 in combination with carbonate apatite granules or rhFGF-2 alone: 12-month randomized controlled trial.
Clin Oral Investig. 2024;28:574.
PubMed Abstract available

BERTL K, Burisch J, Pandis N, Klinge B, et al
Oral health in patients with inflammatory bowel disease: A cross-sectional survey in Sweden.
Clin Oral Investig. 2024;28:573.
PubMed Abstract available

DAVIDOVICH E, Sarne H, Shmueli A, Polak D, et al
Is there an association between salivary immune and microbial profile with dental health in systematically healthy children?
Clin Oral Investig. 2024;28:564.
PubMed Abstract available

September 2024

VESALA T, Venta I, Snall J, Ekholm M, et al
Radiographic identification of symptomless mandibular third molars without clinical pericoronitis.
Clin Oral Investig. 2024;28:561.
PubMed Abstract available

LEE CT, Meng HW, Tran D, Brandon R, et al
Using precision periodontal health care chart (PPHCC) to improve periodontal health.
Clin Oral Investig. 2024;28:542.
PubMed Abstract available

FRIEDMANN A, Jung R, Bilhan H, Ghawi-Begovic HA, et al
Reconstructive surgical therapy of peri-implant defects with ribose cross-linked collagen matrix and crosslinked hyaluronic acid - a prospective case series.
Clin Oral Investig. 2024;28:536.
PubMed Abstract available

LELES CR, de Resende GP, de Oliveira Martins N, Nascimento LN, et al
Mandibular overdentures retained by 1 or 2 implants: a 5-year randomized clinical trial on implant stability and peri-implant outcomes.
Clin Oral Investig. 2024;28:527.
PubMed Abstract available

SIM NCW, Al-Maleki AR, Sulaiman E, Mohamad-Hassan NH, et al
Clinical outcomes and supragingival microbiota analysis around dental implants and teeth in patients with a history of periodontitis: a preliminary study of 6 months follow-up.
Clin Oral Investig. 2024;28:528.
PubMed Abstract available

WERNER N, Frasheri I, Heck K, Ern C, et al
The association between periodontal microbial biomarkers and primary therapy outcome.
Clin Oral Investig. 2024;28:523.
PubMed Abstract available

LIMA L, Gaspar S, Rocha BS, Alves R, et al
Current clinical framework on nitric oxide role in periodontal disease and blood pressure.
Clin Oral Investig. 2024;28:521.
PubMed Abstract available

YE H, Gao X, Ma Y, He S, et al
Role of CD86 on granulocyte in mediating the effect of Genus Roseburia on periodontitis.
Clin Oral Investig. 2024;28:522.
PubMed Abstract available

LIAT C, Haim T
Long-term inflammatory outcome after placement of a novel two-piece dental implant in a dog model experimental peri-implantitis.
Clin Oral Investig. 2024;28:519.
PubMed Abstract available

REYES GARITA P, Tran VT, Chatzopoulou E, Toko-Kamga L, et al
Oral hygiene behaviors and periodontitis among patients with chronic diseases and its impact on tooth loss and oral health-related quality of life: a cross-sectional study of data from the ComPaRe e-cohort.
Clin Oral Investig. 2024;28:518.
PubMed Abstract available

DA SILVA BARBIRATO D, Nogueira NS, Guimaraes TC, Zajdenverg L, et al
Improvement of post-periodontitis-therapy inflammatory state in diabetics: a meta-analysis of randomized controlled trials.
Clin Oral Investig. 2024;28:514.
PubMed Abstract available

BENYEI L, Friedmann A, Ostermann T, Diehl D, et al
Non-surgical treatment of residual periodontal pockets using sodium hypochlorite/amino acid gel and cross-linked hyaluronic acid-a 9-month pilot randomized controlled clinical trial.
Clin Oral Investig. 2024;28:513.
PubMed Abstract available

August 2024

GROENEWEGEN H, Borjas-Howard JF, Meijer K, Lisman T, et al
Association of periodontitis with cardiometabolic and haemostatic parameters.
Clin Oral Investig. 2024;28:506.
PubMed Abstract available

SAHRMANN P, Tarsch J, Schmidlin PR
Comparison of clinical parameters of peri-implantitis and parameters related to tissue macrophage sensitization on TiO(2).
Clin Oral Investig. 2024;28:499.
PubMed Abstract available

BUREEKANCHAN K, Leepong N, Suttapreyasri S
Competence of allogenic demineralized tooth matrix in socket seal surgery for alveolar ridge preservation: a randomized control clinical trial.
Clin Oral Investig. 2024;28:484.
PubMed Abstract available

ABDELKAWY M, Tarrad NAF, Shaker OG, Hassan S, et al
Expression of microRNA-223 and microRNA-214 in gingival crevicular fluid of smoker and nonsmoker periodontitis patients, an observational diagnostic accuracy study.
Clin Oral Investig. 2024;28:480.
PubMed Abstract available

ROMEIRO K, Gominho LF, Rocas IN, Siqueira JF Jr, et al
Postoperative pain in oncological patients subjected to nonsurgical root canal treatment: a prospective case-control study.
Clin Oral Investig. 2024;28:472.
PubMed Abstract available

July 2024

ERDURAN NE, Guncu GN, Akman AC, Acar B, et al
Evaluation of the effect of adjunctive diode laser application on peri-implant crevicular fluid biomarker levels: a randomized controlled trial.
Clin Oral Investig. 2024;28:459.
PubMed Abstract available

CEBESOY EI, Altaca M, Kocak-Oztug NA, Bingul I, et al
Associations between interleukin-10, -12, and - 18 and periodontal health and disease: a cross-sectional study.
Clin Oral Investig. 2024;28:458.
PubMed Abstract available

SAYGUN I, Slezovic MO, Ozkan CK, Bengi VU, et al
Anti-proliferative impact of resveratrol on gingival fibroblasts from juvenile hyaline fibromatosis.
Clin Oral Investig. 2024;28:448.
PubMed Abstract available

SALEH MHA, Mallala D, Alrmali A, Shah B, et al
Residual vertical defects: risk of disease progression, retreatment rates, and cost: a retrospective analysis.
Clin Oral Investig. 2024;28:446.
PubMed Abstract available

SAVRAN L, Saglam M
Clinical effects of omega-3 fatty acids supplementation in the periodontal treatment of smokers and non-smokers with periodontitis: a retrospective study.
Clin Oral Investig. 2024;28:437.
PubMed Abstract available

CETINER DO, Isler SC, Ilikci-Sagkan R, Sengul J, et al
The adjunctive use of antimicrobial photodynamic therapy, light-emitting-diode photobiomodulation and ozone therapy in regenerative treatment of stage III/IV grade C periodontitis: a randomized controlled clinical trial.
Clin Oral Investig. 2024;28:426.
PubMed Abstract available

STAHLI A, De Ry SP, Roccuzzo A, Imber JC, et al
Effect of Coenzyme Q10 on early wound healing after recession coverage surgery with the modified coronally advanced tunnel technique and a connective tissue graft: A 6-month, triple-blinded, randomized, placebo-controlled pilot trial.
Clin Oral Investig. 2024;28:424.
PubMed Abstract available

June 2024

TASTAN EROGLU Z, Babayigit O, Ozkan Sen D, Ucan Yarkac F, et al
Performance of ChatGPT in classifying periodontitis according to the 2018 classification of periodontal diseases.
Clin Oral Investig. 2024;28:407.
PubMed Abstract available

ONDER YB, Alpaslan NZ
Peri-implant phenotype, calprotectin and MMP-8 levels in cases diagnosed with peri-implant disease.
Clin Oral Investig. 2024;28:404.
PubMed Abstract available

DE DAVID SC, Ferreira TGM, da Rocha JM, Moreira CHC, et al
Association between cognitive rumination and periodontal disease, tooth loss and oral health-related quality of life in a rural Southern Brazil population.
Clin Oral Investig. 2024;28:397.
PubMed Abstract available

DIEHL D, Bespalov A, Yildiz MS, Friedmann A, et al
Restoration of posterior teeth by narrow diameter implants in hyperglycemic and normoglycemic patients - 4-year results of a case-control study.
Clin Oral Investig. 2024;28:392.
PubMed Abstract available

KALANI K, Hoang K, Chinam N, Saleh MHA, et al
Factors associated with furcation involvement and fixed prostheses: A cross-sectional study.
Clin Oral Investig. 2024;28:387.
PubMed Abstract available

DA SILVA AMP, Horta Dos Santos FA, Mota RF, Teixeira MKS, et al
Clinical and radiographic outcomes of a two-piece ceramic implant: one year results from a prospective clinical trial.
Clin Oral Investig. 2024;28:380.
PubMed Abstract available

YIN D, Zhan S, Liu Y, Yan L, et al
Experimental models for peri-implant diseases: a narrative review.
Clin Oral Investig. 2024;28:378.
PubMed Abstract available

DOGAN MU, Aricioglu B, Kose TE, Cikman AS, et al
Association between the irrigation-agitation techniques and Periapical Healing of large periapical lesions: a Randomized Controlled Trial.
Clin Oral Investig. 2024;28:376.
PubMed Abstract available

ZHAO J, Zhao P
Association between serum neurofilament light chain and periodontitis.
Clin Oral Investig. 2024;28:369.
PubMed Abstract available

ANGIN AE, Ozkan HD, Saral IP, Aydin B, et al
The incidence and intensity of postoperative pain and Flare-up following the use of three different intracanal medicaments in teeth with posttreatment apical periodontitis: a randomized clinical trial.
Clin Oral Investig. 2024;28:362.
PubMed Abstract available

MATTHES R, Jablonowski L, Pitchika V, Holtfreter B, et al
Training in the use of the water jet and cold atmospheric plasma jet for the decontamination of dental implants.
Clin Oral Investig. 2024;28:355.
PubMed Abstract available

GRAZIANI F, Izzetti R, Peric M, Marhl U, et al
Early periodontal wound healing after chlorhexidine rinsing: a randomized clinical trial.
Clin Oral Investig. 2024;28:354.
PubMed Abstract available

May 2024

LU L, Zhao D, Li C, Sun Y, et al
The role of periodontitis in the development of atherosclerotic cardiovascular disease in participants with the components of metabolic syndrome: a systematic review and meta-analysis.
Clin Oral Investig. 2024;28:339.
PubMed Abstract available

NINI W, Chen L, Jinmei Z, Lufei W, et al
The association between halitosis and periodontitis: a systematic review and meta-analysis.
Clin Oral Investig. 2024;28:341.
PubMed Abstract available

OZCELIK F, Ersahan S, Sirin DA, Ozcelik IK, et al
The importance of mechanosensitive cell mediated prostaglandin and nitric oxide synthesis in the pathogenesis of apical periodontitis: comparative with chronic periodontitis.
Clin Oral Investig. 2024;28:337.
PubMed Abstract available

KALIMERI E, Roccuzzo A, Stahli A, Oikonomou I, et al
Adjunctive use of hyaluronic acid in the treatment of gingival recessions: a systematic review and meta-analysis.
Clin Oral Investig. 2024;28:329.
PubMed Abstract available

REINIGER APP, Cr Tavares R, Ortigara GB, Tatsch KF, et al
Effectiveness of dental floss in the management of gingival health: A 6-month follow-up of a randomized controlled clinical trial.
Clin Oral Investig. 2024;28:319.
PubMed Abstract available

SOLDERER A, Hicklin SP, Assenmacher M, Ender A, et al
Influence of an allogenic collagen scaffold on implant sites with thin supracrestal tissue height: a randomized clinical trial.
Clin Oral Investig. 2024;28:313.
PubMed Abstract available

TARRAD NAF, Shaker OG, Elbanna RMH, AbdelKawy M, et al
"Outcome of non-surgical periodontal treatment on Gal-1 and Gal-3 GCF levels in periodontitis patients: a case-control study".
Clin Oral Investig. 2024;28:309.
PubMed Abstract available

NGUYEN BT, Nguyen-Le CT, Nguyen BT, Le SH, et al
Risk factors associated with the severity of pericoronitis of mandibular third molar.
Clin Oral Investig. 2024;28:307.
PubMed Abstract available

LI Y, Xiang Y, Ren H, Zhang C, et al
Association between periodontitis and dental caries: a systematic review and meta-analysis.
Clin Oral Investig. 2024;28:306.
PubMed Abstract available

MAYR A, Ciper N, Wahl G, Wildenhof J, et al
Longitudinal analysis of microcirculatory parameters in gingival tissues after tooth extraction in patients with different risk profiles for wound healing disorders - a pilot study.
Clin Oral Investig. 2024;28:303.
PubMed Abstract available

XUE Y, Tang Y, Ren Z, Linke L, et al
Association between blood ethylene oxide levels and the prevalence of periodontitis: evidence from NHANES 2013-2014.
Clin Oral Investig. 2024;28:293.
PubMed Abstract available

YAVUZ A, Gungormek HS, Kuru L, Dogan B, et al
Treatment of multiple adjacent gingival recessions using leucocyte- and platelet-rich fibrin with coronally advanced flap: a 12-month split-mouth controlled randomized clinical trial.
Clin Oral Investig. 2024;28:291.
PubMed Abstract available

SOYSAL F, Unsal B, Isler SC, Akca G, et al
Evaluation of salivary stress markers and inflammatory cytokine levels in peri-implantitis patients.
Clin Oral Investig. 2024;28:290.
PubMed Abstract available

BUMM CV, Ern C, Folwaczny J, Wolfle UC, et al
Periodontal grading-estimation of responsiveness to therapy and progression of disease.
Clin Oral Investig. 2024;28:289.
PubMed Abstract available

April 2024

PUCINELLI CM, da Silva RAB, Nelson-Filho P, Lima RB, et al
The effects of NLRP3 inflammasome inhibition or knockout in experimental apical periodontitis induced in mice.
Clin Oral Investig. 2024;28:285.
PubMed Abstract available

SONNENSCHEIN SK, Kilian S, Ruetters M, Ciardo A, et al
Changes in periodontal parameters of splinted versus non-splinted posterior teeth during ten years of supportive periodontal therapy - A retrospective evaluation.
Clin Oral Investig. 2024;28:283.
PubMed Abstract available

RUIZ-ROMERO V, Figueiredo R, Toledano-Serrabona J, Abdelazim Y, et al
Peri-implantitis in patients without regular supportive therapy: Prevalence and risk indicators.
Clin Oral Investig. 2024;28:278.
PubMed Abstract available

WEBER J, Scholz KJ, Schenke IM, Pfab F, et al
Randomized controlled clinical trial on the efficacy of a novel antimicrobial chewing gum in reducing plaque and gingivitis in adolescent orthodontic patients.
Clin Oral Investig. 2024;28:272.
PubMed Abstract available

GURBUZ ES, Guney Z, Kurgan S, Balci N, et al
Oxidative Stress and FOXO-1 Relationship in Stage III Periodontitis.
Clin Oral Investig. 2024;28:270.
PubMed Abstract available

March 2024

DURAISAMY AK, Logani A, Kumar V, Chawla A, et al
Influence of the severity of periodontal disease on the outcome of non-surgical endodontic therapy: A prospective cohort study.
Clin Oral Investig. 2024;28:217.
PubMed Abstract available

ELENA RD, Miren VF, Ana-Maria GD, Xabier MM, et al
Analysis of the treatment of RT2 recessions with a xenogeneic collagen matrix vs. connective tissue graft combined with a coronally advanced flap. A double-blinded randomized clinical trial.
Clin Oral Investig. 2024;28:215.
PubMed Abstract available

LA ROSA GRM, Priolo CY, Abiad RS, Romeo VR, et al
Assessment of bone regeneration after maxillary radicular cyst enucleation with or without bone grafting materials: a retrospective cohort study.
Clin Oral Investig. 2024;28:213.
PubMed Abstract available

ISSA DR, Nassar M, Elamrousy W
Immediately placed implants using simvastatin and autogenous tooth graft combination in periodontally compromised sites: a randomized controlled clinical trial.
Clin Oral Investig. 2024;28:210.
PubMed Abstract available

KAYAR NA, Celik I, Gozlu M, Ustun K, et al
Immunologic burden links periodontitis to acute coronary syndrome: levels of CD4 + and CD8 + T cells in gingival granulation tissue.
Clin Oral Investig. 2024;28:199.
PubMed Abstract available

CAPUCHA T, Krasovsky A, Aslan RA, Ginini JG, et al
Central giant cell granuloma of the jaws-long-term clinical and radiological outcomes of surgical and pharmacological management.
Clin Oral Investig. 2024;28:200.
PubMed Abstract available

CHEN X, Li X, Yang K, Fang J, et al
Maternal periodontitis may cause lower birth weight in children: genetic evidence from a comprehensive Mendelian randomization study on periodontitis and pregnancy.
Clin Oral Investig. 2024;28:194.
PubMed Abstract available

IRANI D, Jungbauer G, Sculean A, Eick S, et al
Effect of sodium hypochlorite gel on bacteria associated with periodontal disease.
Clin Oral Investig. 2024;28:190.
PubMed Abstract available

DONG X, Su Q, Li W, Yang J, et al
The outcome of combined use of iRoot BP Plus and iRoot SP for root-end filling in endodontic microsurgery: a randomized controlled trial.
Clin Oral Investig. 2024;28:188.
PubMed Abstract available

ROJO MG, Lloret MRP, Girones JG
Oral manifestations in women using hormonal contraceptive methods: a systematic review.
Clin Oral Investig. 2024;28:184.
PubMed Abstract available

February 2024

COSTA MSC, Daltro Rosa CDDR, Bento VAA, da Silva Costa SM, et al
Efficacy of acellular xenogeneic dermal matrix graft in the treatment of multiple gingival recessions: systematic review and meta-analysis.
Clin Oral Investig. 2024;28:177.
PubMed Abstract available

DE OLIVEIRA NETO RS, Souza TM, Rosa SJ, Vivan RR, et al
Biological response to endodontic treatment in one versus two-visit: a systematic review and meta-analysis of animal studies.
Clin Oral Investig. 2024;28:173.
PubMed Abstract available

FAHIM SZ, Ghali RM, Hashem AA, Farid MM, et al
The efficacy of 2780 nm Er,Cr;YSGG and 940 nm Diode Laser in root canal disinfection: A randomized clinical trial.
Clin Oral Investig. 2024;28:175.
PubMed Abstract available

LIU Y, Yin T, He M, Fang C, et al
The relationship of dietary flavonoids and periodontitis in US population: a cross-sectional NHANES analysis.
Clin Oral Investig. 2024;28:168.
PubMed Abstract available

BERTL K, Vlachou S, Pandis N, Zampelis A, et al
Repeated local delivery of hyaluronic acid gel as adjunctive treatment of residual pockets in periodontitis patients undergoing supportive periodontal care. A randomized controlled clinical trial.
Clin Oral Investig. 2024;28:158.
PubMed Abstract available

VAZAO AR, Claudino L, Pimpinato PP, Sampaio LV, et al
Experimental apical periodontitis alters salivary biochemical composition and induces local redox state disturbances in the salivary glands of male rats.
Clin Oral Investig. 2024;28:154.
PubMed Abstract available

ZHANG Y, Tang P, Yang Q, Li C, et al
Efficacy of scaling and root planing with and without adjunct Nd:YAG laser therapy on glucose control and periodontal microecological imbalance in periodontitis patients with type 2 diabetes mellitus: a randomized controlled trial.
Clin Oral Investig. 2024;28:143.
PubMed Abstract available

AMARAL RR, Love RM, Braga T, Souza Cortes MI, et al
Impact of root canal preparation using two single-file systems on the intra-radicular microbiome of teeth with primary apical periodontitis.
Clin Oral Investig. 2024;28:139.
PubMed Abstract available

ULIANA JC, Del' Agnese CC, Antoniazzi RP, Kantorski KZ, et al
Autistic individuals have worse oral status than neurotypical controls: a systematic review and meta-analysis of observational studies.
Clin Oral Investig. 2024;28:137.
PubMed Abstract available

OSPINA-CH MV, Acevedo-Godoy M, Perdomo SJ, Chila-Moreno L, et al
Gene variants for the WNT pathway are associated with severity in periodontal disease.
Clin Oral Investig. 2024;28:135.
PubMed Abstract available

LUO S, Liu Z, Jiao R, Li W, et al
The associations of two novel inflammation indexes, systemic immune-inflammation index (SII) and system inflammation response index (SIRI), with periodontitis: evidence from NHANES 2009-2014.
Clin Oral Investig. 2024;28:129.
PubMed Abstract available

January 2024

HASSAN SS, Abdelkawy M, Shaker OG, Tarrad NAF, et al
IL-39 and IL-35 gingival crevicular fluid levels in diabetic patients with generalized periodontitis.
Clin Oral Investig. 2024;28:124.
PubMed Abstract available

HOEFER KC, Weber LT, Barbe AG, Graf I, et al
The tongue microbiome of young patients with chronic kidney disease and their healthy mothers.
Clin Oral Investig. 2024;28:110.
PubMed Abstract available

ROTH JVS, Guarenghi GG, Ferro RM, Valenga HM, et al
Gingival bleeding as a predictor of handgrip strength-an observational study and a pilot randomized clinical trial.
Clin Oral Investig. 2024;28:109.
PubMed Abstract available

GURSOY UK, Gursoy M, Loimaranta V, Rautava J, et al
Salivary Th17 cytokine, human beta-defensin 1-3, and salivary scavenger and agglutinin levels in Crohn's disease.
Clin Oral Investig. 2024;28:108.
PubMed Abstract available

CHENG Z, Gao L, Huang P, Luo D, et al
Genetic causal association between rheumatoid arthritis and periodontitis: a bidirectional two-sample Mendelian randomization analysis.
Clin Oral Investig. 2024;28:107.
PubMed Abstract available

GUL SNS, Eminoglu DO, Laloglu E, Aydin T, et al
Salivary and serum asprosin hormone levels in the 2018 EFP/AAP classification of periodontitis stages and body mass index status: a case-control study.
Clin Oral Investig. 2024;28:91.
PubMed Abstract available

MONTESANI L, Montesani L, Mateo L, Daep C, et al
Antibacterial and clinical effectiveness of a mouthwash with a novel active system of amine + zinc lactate + fluoride: a randomized controlled trial.
Clin Oral Investig. 2024;28:90.
PubMed Abstract available

OZDEMIR EC, Bozkurt E, Yazar FM, Bozan MB, et al
Can delta neutrophil index values predict the success of periodontal treatment in patients with periodontitis?
Clin Oral Investig. 2024;28:82.
PubMed Abstract available

JARDINI MAN, Pedroso JF, Ferreira CL, Nunes CMM, et al
Effect of adjuvant probiotic therapy (Lactobacillus reuteri) in the treatment of periodontitis associated with diabetes mellitus: clinical, controlled, and randomized study.
Clin Oral Investig. 2024;28:80.
PubMed Abstract available

HECK T, Lohana D, Mallela D, Mandil O, et al
Hyperbaric oxygen therapy as an adjunct treatment of periodontitis, MRONJ, and ONJ: a systematic literature review.
Clin Oral Investig. 2024;28:77.
PubMed Abstract available

HUANG B, Liu C, Yang J, Xiang E, et al
Saliva biofilm-derived outer membrane vesicles regulate biofilm formation and immune response of oral epithelial cells on titanium surfaces.
Clin Oral Investig. 2024;28:75.
PubMed Abstract available

AHMED Z, Degroat W, Abdelhalim H, Zeeshan S, et al
Deciphering genomic signatures associating human dental oral craniofacial diseases with cardiovascular diseases using machine learning approaches.
Clin Oral Investig. 2024;28:52.
PubMed Abstract available

December 2023

KARADURAN K, Aydogdu A, Gelisin O, Gunpinar S, et al
Investigating the potential clinical impact of periodontitis on the progression of Alzheimer's disease: a prospective cohort study.
Clin Oral Investig. 2023;28:67.
PubMed Abstract available

RECKELKAMM SL, Kaminska I, Baumeister SE, Ponce-de-Leon M, et al
Targeted proteomics in a population-based study identifies serum PECAM-1 and TRIM21 as inflammation markers for periodontitis.
Clin Oral Investig. 2023;28:59.
PubMed Abstract available

KHUNTHANANITHI P, Lertpimonchai A, Sritara C, Srithanyarat SS, et al
Decreased bone mineral density is associated with an increased number of teeth with periodontitis progression: a 5-year retrospective cohort study.
Clin Oral Investig. 2023;28:51.
PubMed Abstract available

YOLDAS O, Nogueira AVB, Kantar PM, Ziskoven PC, et al
Gingival crevicular fluid levels of apelin correlates with clinical periodontal diagnosis.
Clin Oral Investig. 2023;28:50.
PubMed Abstract available

TORUMTAY CIN G, Lektemur Alpan A, Cevik O
Efficacy of injectable platelet-rich fibrin on clinical and biochemical parameters in non-surgical periodontal treatment: a split-mouth randomized controlled trial.
Clin Oral Investig. 2023;28:46.
PubMed Abstract available

KO YC, Lee J, Lee D, Seol YJ, et al
Diagnostic performance of a point-of-care test device for periodontitis using human saliva: a single-center, single-blinded, confirmatory study.
Clin Oral Investig. 2023;28:27.
PubMed Abstract available

JOSEPH P, Prabhakar P, Holtfreter B, Pink C, et al
Systematic review and meta-analysis of randomized controlled trials evaluating the efficacy of non-surgical periodontal treatment in patients with concurrent systemic conditions.
Clin Oral Investig. 2023;28:21.
PubMed Abstract available

WANG CW, Di Gianfilippo R, Kaciroti N, Ou A, et al
Stability of peri-implantitis surgical reconstructive therapy-a (> 2 years) follow-up of a randomized clinical trial.
Clin Oral Investig. 2023;28:30.
PubMed Abstract available

CUI X, Zhu G, Lin J, Chu CH, et al
The association of aldehyde exposure with the risk of periodontitis: NHANES 2013-2014.
Clin Oral Investig. 2023;28:29.
PubMed Abstract available

PAOLANTONI G, Tatullo M, Miniello A, Sammartino G, et al
Influence of crestal and sub-crestal implant position on development of peri-implant diseases: a 5-year retrospective analysis.
Clin Oral Investig. 2023;28:16.
PubMed Abstract available

FLYBORG J, Renvert S, Anderberg P, Larsson T, et al
Results of objective brushing data recorded from a powered toothbrush used by elderly individuals with mild cognitive impairment related to values for oral health.
Clin Oral Investig. 2023;28:8.
PubMed Abstract available

GUZELDEMIR-AKCAKANAT E, Sunnetci-Akkoyunlu D, Balta-Uysal VM, Ozer T, et al
Differentially expressed miRNAs associated with generalized aggressive periodontitis.
Clin Oral Investig. 2023;28:7.
PubMed Abstract available

PABST A, Becker P, Kuchen R, Schumann S, et al
A comparative study of cyanoacrylate-based tissue adhesive and surgical sutures on marginal flap stability following coronally advanced flap.
Clin Oral Investig. 2023;28:5.
PubMed Abstract available

DE RABELLO DGD, Valera MC, Corazza BJM, Dos Santos LM, et al
Clinical efficacy of endodontic protocols on reducing cultivable bacteria and endotoxin in infected root canal in patients submitted to head and neck radiotherapy: a randomised clinical trial.
Clin Oral Investig. 2023;27:7199-7207.
PubMed Abstract available

SABRI H, SamavatiJame F, Sarkarat F, Wang HL, et al
Clinical efficacy of Vestibular Incision Subperiosteal Tunnel Access (VISTA) for treatment of multiple gingival recession defects: a systematic review, meta-analysis and meta-regression.
Clin Oral Investig. 2023;27:7171-7187.
PubMed Abstract available

ALVES-COSTA S, Leite FRM, Ladeira LLC, Lima-Soares F, et al
Behavioral and metabolic risk factors associated with periodontitis in Brazil, 1990-2019: a multidimensional analysis for the Global Burden of Disease Study 2019.
Clin Oral Investig. 2023;27:7909-7917.
PubMed Abstract available

KOLERMAN R, Abu-Rabie H, Sculean A, Chaushu L, et al
Simultaneous implant placement and restoration with guided bone regeneration in the mandibular anterior region.
Clin Oral Investig. 2023;27:7821-7832.
PubMed Abstract available

BEZERRA DE MELO N, Sobreira Duarte LN, Maia Vieira Pereira C, da Silva Barbosa J, et al
Thermographic examination of gingival phenotypes: correlation between morphological and thermal parameters.
Clin Oral Investig. 2023;27:7705-7714.
PubMed Abstract available

CORBELLA S, Morandi B, Calciolari E, Alberti A, et al
The influence of implant position and of prosthetic characteristics on the occurrence of peri-implantitis: a retrospective study on periapical radiographs.
Clin Oral Investig. 2023;27:7261-7271.
PubMed Abstract available

LU J, Kahler B, Jiang X, Lu Z, et al
Treatment outcomes of regenerative endodontic procedures in nonvital mature permanent teeth: a retrospective study.
Clin Oral Investig. 2023;27:7531-7543.
PubMed Abstract available

DE JESUS OLIVEIRA LS, de Figueiredo FED, Dantas JA, Ribeiro MAG, et al
Impact XP-endo finisher on the 1-year follow-up success of posterior root canal treatments: a randomized clinical trial.
Clin Oral Investig. 2023;27:7595-7603.
PubMed Abstract available

CAMPONOGARA JG, de Ferreira TGM, Pelissari TR, Anversa AM, et al
Demographics, smoking status, and systemic health factors associated with apical periodontitis in a Brazilian rural population: a cross-sectional study.
Clin Oral Investig. 2023;27:7319-7325.
PubMed Abstract available

PARLAK HM, Yilmaz BT, Durmaz MH, Toz H, et al
The effects of vertically coronally advanced flap and free gingival graft techniques on shallow vestibule: a randomized comparative prospective trial.
Clin Oral Investig. 2023;27:7425-7436.
PubMed Abstract available

CEKICI A, Sahinkaya S, Donmez MF, Turkmen E, et al
Sirtuin6 and Lipoxin A4 levels are decreased in severe periodontitis.
Clin Oral Investig. 2023;27:7407-7415.
PubMed Abstract available

SAREMI L, Esmaeili S, Ghaffari ME, Shahbazi S, et al
Evaluation of matrix metalloproteinase-1, -2, -3, -7, and -13 gene polymorphisms in patients with chronic periodontitis and healthy controls.
Clin Oral Investig. 2023;27:7417-7423.
PubMed Abstract available

KARATAS E, Kul A, Camilleri J, Yonel Z, et al
Association between rheumatoid arthritis and pulpal-periapical pathology: a systematic review.
Clin Oral Investig. 2023;27:7019-7028.
PubMed Abstract available

November 2023

LOMBARDO G, D'Agostino A, Nocini PF, Signoriello A, et al
Clinical outcomes and periodontal conditions of dental implants placed in free fibula flaps (FFF): a retrospective study with a mean follow-up of 6 years.
Clin Oral Investig. 2023 Nov 2. doi: 10.1007/s00784-023-05364.
PubMed Abstract available

MIKHAIL FF, El Menoufy H, El Kilani NS
Assessment of clinical outcomes and patient response to gingival depigmentation using a scalpel, ceramic bur, and diode laser 980 nm.
Clin Oral Investig. 2023;27:6939-6950.
PubMed Abstract available

WEHNER C, Tur D, Durstberger G, Laky M, et al
Effects of enamel matrix derivative in nonsurgical periodontal therapy on pro-inflammatory profiles, microbial environment and clinical outcome: a randomized clinical trial.
Clin Oral Investig. 2023;27:6493-6502.
PubMed Abstract available

ALVES JM, Germano DB, Kim YJ, Fonseca FAH, et al
Modulation of monocyte subtypes in diabetes after non-surgical periodontal treatment.
Clin Oral Investig. 2023;27:6847-6854.
PubMed Abstract available

MARKOU N, Pepelassi E, Madianos P, Simopoulou M, et al
Systemic inflammatory markers following adjunctive Nd:YAG (1064 nm) laser irradiation to step 2 of periodontal therapy: a 12-month, randomized, controlled trial.
Clin Oral Investig. 2023;27:6925-6935.
PubMed Abstract available

GUNEY Z, Kurgan S, Onder C, Tayman MA, et al
Wnt signaling in periodontitis.
Clin Oral Investig. 2023;27:6801-6812.
PubMed Abstract available

ISOLA G, Polizzi A, Mascitti M, Santonocito S, et al
Impact of periodontitis on circulating cell-free DNA levels as a measure of cardiovascular disease.
Clin Oral Investig. 2023;27:6855-6863.
PubMed Abstract available

DE VASCONCELOS GURGEL BC, Peixe PG, Queiroz SIML, de Almeida Freitas R, et al
Comparison of immunoexpression of dendritic cells, mast cells and blood vessels in periodontal disease between adults and elderly.
Clin Oral Investig. 2023;27:6823-6833.
PubMed Abstract available

RAMANAUSKAITE A, Kruger N, Obreja K, Borchert F, et al
Influence of antiresorptive/antiangiogenic therapy on the surgical treatment outcomes of experimentally induced peri-implantitis lesions.
Clin Oral Investig. 2023;27:6657-6666.
PubMed Abstract available

YANG Q, Fan Z, Tang P, Jiang Y, et al
Characteristics of mandibular anterior alveolar bone in patients with different degrees of periodontitis: a retrospective study based on CBCT.
Clin Oral Investig. 2023;27:6709-6721.
PubMed Abstract available

LI M, Zhang Y, Zhang A, Cai H, et al
Association between polymorphisms of anti-inflammatory gene alleles and periodontitis risk in a Chinese Han population.
Clin Oral Investig. 2023;27:6689-6700.
PubMed Abstract available

FERRAROTTI F, Baima G, Rendinelli M, Citterio F, et al
Pocket closure after repeated subgingival instrumentation: a stress test to the EFP guideline for stage III-IV periodontitis.
Clin Oral Investig. 2023;27:6701-6708.
PubMed Abstract available

BUMM CV, Wolfle UC, Kessler A, Werner N, et al
Influence of decision-making algorithms on the diagnostic accuracy using the current classification of periodontal diseases-a randomized controlled trial.
Clin Oral Investig. 2023;27:6589-6596.
PubMed Abstract available

RAMANAUSKAITE E, Machiulskiene V, Shirakata Y, Dvyliene UM, et al
Clinical evaluation of sodium hypochlorite/amino acids and cross-linked hyaluronic acid adjunctive to non-surgical periodontal treatment: a randomized controlled clinical trial.
Clin Oral Investig. 2023;27:6645-6656.
PubMed Abstract available

LONGO BC, Rohling IB, Silva PLMOE, de Morais MEF, et al
Antineoplastic therapy in childhood cancer patients presents a negative impact in the periodontal tissues: a cohort study.
Clin Oral Investig. 2023;27:6637-6644.
PubMed Abstract available

SFREDDO CS, Oliveira LM, Gomes BZ, Ardenghi TM, et al
Discriminant validity of the current gingivitis classification in adolescents: a cohort study.
Clin Oral Investig. 2023;27:6513-6521.
PubMed Abstract available

BAIMA G, Shin HS, Arrica M, Lafori A, et al
The co-occurrence of the two main oral diseases: periodontitis and dental caries.
Clin Oral Investig. 2023;27:6483-6492.
PubMed Abstract available

LU X, Li P, Li J, Hu J, et al
Clinical diagnostic value of IL-14, 1L-16 and SAA in periodontitis.
Clin Oral Investig. 2023;27:6627-6635.
PubMed Abstract available

PAMUK F, Lutfioglu M, Paksoy T, Koyuncuoglu CZ, et al
Impact of low-level laser therapy as an adjunct to non-surgical periodontal treatment on the levels of tissue plasminogen activator and plasminogen activator inhibitor 1 in Stage 3-4, Grade C periodontitis patients: a split-mouth, randomized control s
Clin Oral Investig. 2023;27:6439-6449.
PubMed Abstract available

October 2023

GADZO N, Ioannidis A, Naenni N, Husler J, et al
Survival and complication rates of two dental implant systems supporting fixed restorations: 10-year data of a randomized controlled clinical study.
Clin Oral Investig. 2023 Oct 31. doi: 10.1007/s00784-023-05323.
PubMed Abstract available

GURBUZ S, Altikat M
The association between periodontitis patients' chief complaints and the stage of periodontitis: A clinical retrospective study.
Clin Oral Investig. 2023;27:6261-6272.
PubMed Abstract available

BRINAR S, Skvarca A, Gaspirc B, Schara R, et al
The effect of antimicrobial photodynamic therapy on periodontal disease and glycemic control in patients with type 2 diabetes mellitus.
Clin Oral Investig. 2023;27:6235-6244.
PubMed Abstract available

September 2023

ALAMRI MM, Antonoglou GN, Proctor G, Balsa-Castro C, et al
Biomarkers for diagnosis of stage III, grade C with molar incisor pattern periodontitis in children and young adults: a systematic review and meta-analysis.
Clin Oral Investig. 2023;27:4929-4955.
PubMed Abstract available

GUVENC KK, Fentoglu O, Calapoglu M, Aksoy F, et al
Periodontal and cardiovascular therapies modify specialized pro-resolving lipid mediator (sPRLM) (LPXA4, PD1, RvE1, RvD1, and MaR1)-mediated pathway: the first pilot clinical study.
Clin Oral Investig. 2023;27:5549-5558.
PubMed Abstract available

RAMIREZ V, Weber L, Hernandez M, Realini O, et al
Obesity is related to maternal periodontitis severity in pregnancy: a cross-sectional study.
Clin Oral Investig. 2023;27:5509-5518.
PubMed Abstract available

GINESIN O, Mayer Y, Gabay E, Rotenberg D, et al
Revealing leukocyte populations in human peri-implantitis and periodontitis using flow cytometry.
Clin Oral Investig. 2023;27:5499-5508.
PubMed Abstract available

PIEDRA-HERNANDEZ L, Batista-Cardenas D, Gomez-Fernandez A, Ramirez K, et al
Dental anxiety and oral health-related quality of life before and after non-surgical periodontal treatment.
Clin Oral Investig. 2023;27:5459-5474.
PubMed Abstract available

GOUSOPOULOU E, Bakopoulou A, Laskaris D, Gousopoulos E, et al
Characterization of the soft-tissue wall lining residual periodontal pockets and implications in periodontal wound healing.
Clin Oral Investig. 2023;27:5031-5040.
PubMed Abstract available

FEUERRIEGEL GC, Burian E, Sollmann N, Leonhardt Y, et al
Evaluation of 3D MRI for early detection of bone edema associated with apical periodontitis.
Clin Oral Investig. 2023;27:5403-5412.
PubMed Abstract available

CHACKARTCHI T, Bosshardt DD, Imber JC, Stahli A, et al
Histological evaluation following treatment of recession-type defects with coronally advanced flap and a novel human recombinant amelogenin.
Clin Oral Investig. 2023;27:5041-5048.
PubMed Abstract available

ROSER CJ, Zenthofer A, Lux CJ, Rues S, et al
A new CAD/CAM tooth mobility simulating model for dental in vitro investigations.
Clin Oral Investig. 2023;27:5131-5140.
PubMed Abstract available

August 2023

WU Q
Regenerative endodontic treatment using autologous blood from alveolar bone for mature permanent premolar with apical periodontitis: a case report.
Clin Oral Investig. 2023;27:4869-4874.
PubMed Abstract available

GOMES BPFA, Berber VB, Chiarelli-Neto VM, Aveiro E, et al
Microbiota present in combined endodontic-periodontal diseases and its risks for endocarditis.
Clin Oral Investig. 2023;27:4757-4771.
PubMed Abstract available

CAO R, Zhang S, Zhang J, Miao D, et al
Association between serum HE4 and poor periodontal health in adult women.
Clin Oral Investig. 2023;27:4809-4816.
PubMed Abstract available

BAUMEISTER SE, Reckelkamm SL, Ehmke B, Nolde M, et al
Physical activity and the risk of periodontitis: an instrumental variable study.
Clin Oral Investig. 2023;27:4803-4808.
PubMed Abstract available

STAHLI A, Parkanyi L, Aroca S, Stavropoulos A, et al
The effect of connective tissue graft or a collagen matrix on epithelial differentiation around teeth and implants: a preclinical study in minipigs.
Clin Oral Investig. 2023;27:4553-4566.
PubMed Abstract available

LIU X, Dai B, Chuai Y, Hu M, et al
Associations between vitamin D levels and periodontal attachment loss.
Clin Oral Investig. 2023;27:4727-4733.
PubMed Abstract available

LI Q, Li S, Xiao Q, Hu W, et al
Clinical investigation of gingival papilla recession after orthodontic treatment in adults.
Clin Oral Investig. 2023;27:4425-4432.
PubMed Abstract available

XU X, Zhou Y, Liu C, Zhao L, et al
Effects of water flossing on gingival inflammation and supragingival plaque microbiota: a 12-week randomized controlled trial.
Clin Oral Investig. 2023;27:4567-4577.
PubMed Abstract available

XUE F, Zhang R, Liu J, Duan J, et al
Digitally measured exposed root surface area for predicting the effectiveness of modified coronally advanced tunnel combined de-epithelialized gingival grafting in the treatment of multiple adjacent gingival recessions.
Clin Oral Investig. 2023;27:4503-4512.
PubMed Abstract available

EL-SIOUFI I, Oikonomou I, Koletsi D, Bobetsis YA, et al
Clinical evaluation of different alveolar ridge preservation techniques after tooth extraction: a randomized clinical trial.
Clin Oral Investig. 2023;27:4471-4480.
PubMed Abstract available

LU JW, Huang SH, Lei XX, Deng L, et al
Clinical outcomes of diode laser as an adjunct to nonsurgical periodontal therapy for residual periodontal pockets in mandibular second molars-a randomized controlled clinical trial.
Clin Oral Investig. 2023;27:4493-4501.
PubMed Abstract available

MAINAS G, Santamaria P, Ide M, Longo V, et al
Could dietary restrictions affect periodontal disease? A systematic review.
Clin Oral Investig. 2023;27:4107-4116.
PubMed Abstract available

July 2023

CASTELLAR-MENDOZA C, Castillo DM, Chila-Moreno L, Bautista-Molano W, et al
Porphyromonas gulae and PPAD antibodies are not related to citrullination in rheumatoid arthritis.
Clin Oral Investig. 2023;27:3509-3519.
PubMed Abstract available

NAZIKER Y, Ertugrul AS
Aesthetic evaluation of free gingival graft applied by partial de-epithelialization and free gingival graft applied by conventional method: a randomized controlled clinical study.
Clin Oral Investig. 2023;27:4029-4038.
PubMed Abstract available

CHEN D, Li Z, Li Z, Sun Y, et al
Transcriptome analysis of human peri-implant soft tissue and periodontal gingiva: a paired design study.
Clin Oral Investig. 2023;27:3937-3948.
PubMed Abstract available

LIMIROLI E, Calo A, Cortellini P, Eickholz P, et al
The influence of interradicular anatomy on the predictability of periodontal regenerative therapy of furcation defects: a retrospective, multicenter clinical study.
Clin Oral Investig. 2023;27:3779-3786.
PubMed Abstract available

BURIAN E, Feuerriegel G, Sollmann N, Burian G, et al
Visualization of clinically silent, odontogenic maxillary sinus mucositis originating from periapical inflammation using MRI: a feasibility study.
Clin Oral Investig. 2023;27:3705-3712.
PubMed Abstract available

AFACAN B, Ilhan HA, Kose T, Emingil G, et al
Gingival crevicular fluid galectin-3 and interleukin-1 beta levels in stage 3 periodontitis with grade B and C.
Clin Oral Investig. 2023;27:3749-3758.
PubMed Abstract available

VAZQUEZ-REZA M, Lopez-Dequidt I, Ouro A, Iglesias-Rey R, et al
Periodontitis is associated with subclinical cerebral and carotid atherosclerosis in hypertensive patients: A cross-sectional study.
Clin Oral Investig. 2023;27:3489-3498.
PubMed Abstract available

ALSHOIBY MM, Fawzy El-Sayed KM, Elbattawy W, Hosny MM, et al
Injectable platelet-rich fibrin with demineralized freeze-dried bone allograft compared to demineralized freeze-dried bone allograft in intrabony defects of patients with stage-III periodontitis: a randomized controlled clinical trial.
Clin Oral Investig. 2023;27:3457-3467.
PubMed Abstract available

GONZALEZ-FEBLES J, Romandini M, Laciar-Oudshoorn F, Noguerol F, et al
Tunnel vs. coronally advanced flap in combination with a connective tissue graft for the treatment of multiple gingival recessions: a multi-center randomized clinical trial.
Clin Oral Investig. 2023;27:3627-3638.
PubMed Abstract available

ROMANO F, Bebars A, Ortu V, Bottone M, et al
Effect of psychosocial stress and coping strategies on non-surgical periodontal therapy in patients with generalized stage III/IV periodontitis: a longitudinal intervention study.
Clin Oral Investig. 2023;27:3479-3487.
PubMed Abstract available

TEODORO DE CARVALHO VA, Mattedi MAM, Vergara-Buenaventura A, Muniz FWMG, et al
Influence of graft thickness on tunnel technique procedures for root coverage: a pilot split-mouth randomized controlled trial.
Clin Oral Investig. 2023;27:3469-3477.
PubMed Abstract available

SANTAMARIA P, Paolantonio M, Romano L, Serroni M, et al
Gingival phenotype changes after different periodontal plastic surgical techniques: a single-masked randomized controlled clinical trial.
Clin Oral Investig. 2023;27:3423-3435.
PubMed Abstract available

June 2023

CHEN S, Darby I
Inter-implant distance and buccal bone thickness for a novel implant design: a preclinical study.
Clin Oral Investig. 2023;27:3261-3274.
PubMed Abstract available

MANASA B, Baiju KV, Ambili R
Efficacy of injectable platelet-rich fibrin (i-PRF) for gingival phenotype modification: a split-mouth randomized controlled clinical trial.
Clin Oral Investig. 2023;27:3275-3283.
PubMed Abstract available

LAFAURIE GI, Castillo DM, Iniesta M, Sanz M, et al
Differential analysis of culturable and unculturable subgingival target microorganisms according to the stages of periodontitis.
Clin Oral Investig. 2023;27:3029-3043.
PubMed Abstract available

DEMIRCI MB, Daltaban O, Ustun K
Salivary bactericidal/permeability-increasing protein: A novel inflammatory marker associated with periodontitis.
Clin Oral Investig. 2023;27:3159-3167.
PubMed Abstract available

ARANGO JIMENEZ N, Morales Vera DZ, Latorre Uriza C, Velosa-Porras J, et al
Relationship of obstructive sleep apnea with periodontal condition and its local and systemic risk factors.
Clin Oral Investig. 2023;27:2823-2832.
PubMed Abstract available

TORRES-MONJARAS AP, Sanchez-Gutierrez R, Hernandez-Castro B, Gonzalez-Baranda L, et al
Bacteria associated with apical periodontitis promotes in vitro the differentiation of macrophages to osteoclasts.
Clin Oral Investig. 2023;27:3139-3148.
PubMed Abstract available

SCHWARZ F, Becker K, Lukman F, Muller KM, et al
Influence of antiresorptive/antiangiogenic therapy on the extension of experimentally induced peri-implantitis lesions.
Clin Oral Investig. 2023;27:3009-3019.
PubMed Abstract available

MARKOU N, Papadelli A, Nikolidakis D, Pepelassi E, et al
Adjunctive Nd:YAG laser irradiation in the treatment of stage III/IV periodontitis: a 12-month, randomized, controlled trial.
Clin Oral Investig. 2023;27:3045-3056.
PubMed Abstract available

VILARRASA J, Soldini MC, Pons R, Valles C, et al
Outcome indicators of non-surgical therapy of peri-implantitis: a prospective case series analysis.
Clin Oral Investig. 2023;27:3125-3138.
PubMed Abstract available

TURKMEN E, Uzun EV, Bozaba F, Balci N, et al
Salivary irisin level is higher and related with interleukin-6 in generalized periodontitis.
Clin Oral Investig. 2023;27:3001-3008.
PubMed Abstract available

MORON-CONEJO B, Sanz-Sanchez I, Salido MP, Martinez-Rus F, et al
The effect of a convergent transmucosal neck on soft tissues and radiographic outcomes: a 1-year follow-up randomized controlled trial.
Clin Oral Investig. 2023;27:2923-2933.
PubMed Abstract available

DING M, Zhang Z, Chen Z, Song J, et al
Association between periodontitis and breast cancer: two-sample Mendelian randomization study.
Clin Oral Investig. 2023;27:2843-2849.
PubMed Abstract available

BULIGON MP, Marin JA, Wolle CFB, Liedke GS, et al
Apical periodontitis and associated factors in a rural population of southern Brazil: a multilevel analysis.
Clin Oral Investig. 2023;27:2887-2897.
PubMed Abstract available

EL-WAKEEL NM, Shalaby ZF, Abdulmaguid RF, Elhamed SSA, et al
Local gingival crevicular fluid, synovial fluid, and circulating levels of prolactin hormone in patients with moderately active rheumatoid arthritis and stage III and IV periodontitis before and after non-surgical periodontal treatment-a controlled tr
Clin Oral Investig. 2023;27:2813-2821.
PubMed Abstract available

ISMAIL HH, Obeid M, Hassanien E
Efficiency of diode laser in control of post-endodontic pain: a randomized controlled trial.
Clin Oral Investig. 2023;27:2797-2804.
PubMed Abstract available

TOY VE, Ataoglu T, Eltas A, Otlu HG, et al
Obesity as a modifying factor of periodontal therapy outcomes: local and systemic adipocytokines and oxidative stress markers.
Clin Oral Investig. 2023;27:2763-2773.
PubMed Abstract available

MENSI M, Caselli E, D'Accolti M, Soffritti I, et al
Efficacy of the additional use of subgingival air-polishing with erythritol powder in the treatment of periodontitis patients: a randomized controlled clinical trial. Part II: effect on sub-gingival microbiome.
Clin Oral Investig. 2023;27:2547-2563.
PubMed Abstract available

DE JESUS OLIVEIRA LS, de Figueiredo FED, Correa MB, Faria-E-Silva AL, et al
Supplementary use of the XP-endo Finisher on postoperative pain in posterior teeth with periapical lesions: a randomized clinical trial.
Clin Oral Investig. 2023;27:2565-2572.
PubMed Abstract available

HERRERA D, Serrano J, Roldan S, Alonso B, et al
Oral and systemic health: is there a "new" link with COVID-19?
Clin Oral Investig. 2023;27.
PubMed Abstract available

May 2023

WIESMULLER V, Kasslatter M, Zengin B, Zotz D, et al
Cleansing efficacy of an oral irrigator with microburst technology in orthodontic patients-a randomized-controlled crossover study.
Clin Oral Investig. 2023;27:2089-2095.
PubMed Abstract available

KUCIC AC, Gaspersic R
Minimally invasive non-surgical therapy (MINST) in stage III periodontitis patients: 6-month results of a split-mouth, randomised controlled clinical trial.
Clin Oral Investig. 2023;27:2075-2087.
PubMed Abstract available

YU L, Firatli Y, Elmanfi S, Gursoy M, et al
Localization and expression profiles of gingival monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) and mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT-1).
Clin Oral Investig. 2023;27:2065-2074.
PubMed Abstract available

GODOI-JR EP, Bronzato JD, Francisco PA, Bicego-Pereira EC, et al
Microbiological profile of root canals indicated for endodontic retreatment due to secondary endodontic infections or for prosthetic reasons.
Clin Oral Investig. 2023;27:2049-2064.
PubMed Abstract available

TRULLENQUE-ERIKSSON A, Derks J, Andersson JS
Onset of periodontitis - a registry-based cohort study.
Clin Oral Investig. 2023;27:2187-2195.
PubMed Abstract available

DA SILVA BARBIRATO D, Fogacci MF, Guimaraes TC, de Carvalho DP, et al
Protective effect of Chromobacterium violaceum and violacein against bone resorption by periodontitis.
Clin Oral Investig. 2023;27:2175-2186.
PubMed Abstract available

BINGOL AC, Bingol M, Pandis N, Stolz S, et al
Dietary and metabolic effects on the oral status of patients with phenylketonuria: a nation-based cross-sectional study.
Clin Oral Investig. 2023;27:1981-1991.
PubMed Abstract available

GORSKI B, Skierska I, Szerszen M, Manka-Malara K, et al
Tunnel technique with cross-linked hyaluronic acid in addition to subepithelial connective tissue graft, compared with connective tissue graft alone, for the treatment of multiple gingival recessions: 6-month outcomes of a randomized clinical trial.
Clin Oral Investig. 2023;27:2395-2406.
PubMed Abstract available

ANNUNZIATA M, Donnarumma G, Guida A, Nastri L, et al
Clinical and microbiological efficacy of indocyanine green-based antimicrobial photodynamic therapy as an adjunct to non-surgical treatment of periodontitis: a randomized controlled clinical trial.
Clin Oral Investig. 2023;27:2385-2394.
PubMed Abstract available

CHEW RJJ, Tang YL, Lin XYS, Oh FJB, et al
Toll-like receptor-4 activation by subgingival biofilm and periodontal treatment response.
Clin Oral Investig. 2023;27:2139-2147.
PubMed Abstract available

OZENER HO, Kuru L, Kadir T, Kuru B, et al
Bifidobacterium animalis subsp. lactis as adjunct to non-surgical periodontal treatment in periodontitis: a randomized controlled clinical trial.
Clin Oral Investig. 2023;27:1965-1972.
PubMed Abstract available

JIANG Y, Cui W, Chen J, Wu Q, et al
Clinical, radiographic characterizations and complications of maxillary molar in a periodontitis population: a retrospective study based on CBCT radiography.
Clin Oral Investig. 2023;27:2335-2346.
PubMed Abstract available

OSTOS-AGUILAR BI, Pinheiro Furquim C, Muniz FWMG, Faveri M, et al
Clinical efficacy of hyaluronic acid in the treatment of periodontal intrabony defect: a systematic review and meta-analysis.
Clin Oral Investig. 2023;27:1923-1935.
PubMed Abstract available

April 2023

CORBELLA S, Calciolari E, Donos N, Alberti A, et al
Laser treatments as an adjunct to non-surgical periodontal therapy in subjects with periodontitis and type 2 diabetes mellitus: a systematic review and meta-analysis.
Clin Oral Investig. 2023;27:1311-1327.
PubMed Abstract available

TANG P, Meng Z, Song X, Huang J, et al
Influence of different mucosal phenotype on early and long-term marginal bone loss around implants: a systematic review and meta-analysis.
Clin Oral Investig. 2023;27:1391-1407.
PubMed Abstract available

GREGGIANIN BF, Marques AEM, Amato AA, de Lima CL, et al
Effect of periodontal therapy on insulin resistance in adults with dysglycemia and periodontitis: a systematic review and meta-analysis.
Clin Oral Investig. 2023;27:1329-1342.
PubMed Abstract available

LIMIROLI E, Calo A, Limiroli A, Cortinovis I, et al
Radiographic ratios for classifying furcation anatomy: proposal of a new evaluation method and an intra-rater and inter-rater operator reliability study.
Clin Oral Investig. 2023;27:1541-1546.
PubMed Abstract available

MUNDT T, Heinemann F, Muller J, Schwahn C, et al
Survival and stability of strategic mini-implants with immediate or delayed loading under removable partial dentures: a 3-year randomized controlled clinical trial.
Clin Oral Investig. 2023;27:1767-1779.
PubMed Abstract available

MATHIAS-SANTAMARIA IF, Santamaria MP, Silveira CA, Martinho FC, et al
Evaluation of a novel restorative protocol to treat non-carious cervical lesion associated with gingival recession: a 2-year follow-up randomized clinical trial.
Clin Oral Investig. 2023;27:1781-1792.
PubMed Abstract available

SAMARTH G, Kolte A, Kolte R, Bajaj V, et al
Comparative evaluation of demineralized freeze-dried bone allograft with and without concentrated growth factor membrane in the treatment of periodontal intrabony defects: a randomized controlled clinical trial.
Clin Oral Investig. 2023;27:1645-1657.
PubMed Abstract available

DRITSAS K, Halazonetis D, Ghamri M, Sculean A, et al
Accurate gingival recession quantification using 3D digital dental models.
Clin Oral Investig. 2023;27:1697-1705.
PubMed Abstract available

March 2023

CHATZOPOULOS GS, Koidou VP, Tsalikis L
Local drug delivery in the treatment of furcation defects in periodontitis: a systematic review.
Clin Oral Investig. 2023;27:955-970.
PubMed Abstract available

BOSTANCI N, Belibasakis GN
Precision periodontal care: from omics discoveries to chairside diagnostics.
Clin Oral Investig. 2023;27:971-978.
PubMed Abstract available

MACHADO A, Pereira I, Costa F, Brandao A, et al
Randomized clinical study of injectable dextrin-based hydrogel as a carrier of a synthetic bone substitute.
Clin Oral Investig. 2023;27:979-994.
PubMed Abstract available

GROENEWEGEN H, Delli K, Vissink A, Spijkervet FKL, et al
Immune markers and microbial factors are related with periodontitis severity in people with HIV.
Clin Oral Investig. 2023;27:1255-1263.
PubMed Abstract available

RUP AG, Izquierdo CM, Rios FS, Costa RDSA, et al
Classification of a patient's caries activity based on lesion activity assessment among adults: findings from a prospective cohort study.
Clin Oral Investig. 2023;27:1123-1131.
PubMed Abstract available

LAKSHMI MR, Gottumukkala SNVS, Penmetsa GS, Ramesh KSV, et al
Clinical outcomes of root coverage using porcine-derived collagen matrix with modified coronally advanced tunnel technique (MCAT) in multiple gingival recessions in smokers - a randomized controlled clinical trial.
Clin Oral Investig. 2023;27:1101-1111.
PubMed Abstract available

January 2023

AYELE S, Sharo N, Chrcanovic BR
Marginal bone loss around dental implants: comparison between diabetic and non-diabetic patients-a retrospective clinical study.
Clin Oral Investig. 2023 Jan 30. doi: 10.1007/s00784-023-04872.
PubMed Abstract available

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