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Articles published in Neurobiol Dis

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    June 2021
  1. ANDREOLI L, Abbaszadeh M, Cao X, Cenci MA, et al
    Distinct patterns of dyskinetic and dystonic features following D1 or D2 receptor stimulation in a mouse model of parkinsonism.
    Neurobiol Dis. 2021 Jun 18:105429. doi: 10.1016/j.nbd.2021.105429.
    PubMed     Abstract available


    May 2021
  2. FAUSER M, Ricken M, Markert F, Weis N, et al
    Subthalamic nucleus deep brain stimulation induces sustained neurorestoration in the mesolimbic dopaminergic system in a Parkinson's disease model.
    Neurobiol Dis. 2021 May 24:105404. doi: 10.1016/j.nbd.2021.105404.
    PubMed     Abstract available


  3. TOMKINS JE, Manzoni C
    Advances in protein-protein interaction network analysis for Parkinson's disease.
    Neurobiol Dis. 2021;155:105395.
    PubMed     Abstract available


  4. BRAZHNIK E, Novikov N, McCoy AJ, Ilieva NM, et al
    Early decreases in cortical mid-gamma peaks coincide with the onset of motor deficits and precede exaggerated beta build-up in rat models for Parkinson's disease.
    Neurobiol Dis. 2021 May 14:105393. doi: 10.1016/j.nbd.2021.105393.
    PubMed     Abstract available


    April 2021
  5. YIN Z, Zhu G, Zhao B, Bai Y, et al
    Local field potentials in Parkinson's disease: a frequency-based review.
    Neurobiol Dis. 2021 Apr 28:105372. doi: 10.1016/j.nbd.2021.105372.
    PubMed     Abstract available


  6. PETERS OM, Weiss A, Metterville J, Song L, et al
    Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease.
    Neurobiol Dis. 2021 Apr 20:105368. doi: 10.1016/j.nbd.2021.105368.
    PubMed     Abstract available


    March 2021
  7. BRUMBERG J, Kuzkina A, Lapa C, Mammadova S, et al
    Dermal and cardiac autonomic fiber involvement in Parkinson's disease and multiple system atrophy.
    Neurobiol Dis. 2021 Mar 12:105332. doi: 10.1016/j.nbd.2021.105332.
    PubMed     Abstract available


  8. CHU Y, Kordower JH
    GDNF signaling in subjects with minimal motor deficits and Parkinson's disease.
    Neurobiol Dis. 2021 Mar 5:105298. doi: 10.1016/j.nbd.2021.105298.
    PubMed     Abstract available


  9. ZOU L, Zhang X, Xiong M, Meng L, et al
    Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
    Neurobiol Dis. 2021 Mar 4:105326. doi: 10.1016/j.nbd.2021.105326.
    PubMed     Abstract available


    February 2021
  10. JIANG M, Tu HT, Zhang K, Zhang W, et al
    Impaired neurogenesis in the hippocampus of an adult VPS35 mutant mouse model of Parkinson's disease through interaction with APP.
    Neurobiol Dis. 2021 Feb 23:105313. doi: 10.1016/j.nbd.2021.105313.
    PubMed     Abstract available


  11. DE MIRANDA BR, Castro SL, Rocha EM, Bodle CR, et al
    The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease.
    Neurobiol Dis. 2021 Feb 23:105312. doi: 10.1016/j.nbd.2021.105312.
    PubMed     Abstract available


  12. KINNERUP MB, Sommerauer M, Damholdt MF, Schaldemose JL, et al
    Preserved noradrenergic function in Parkinson's disease patients with rest tremor.
    Neurobiol Dis. 2021 Feb 4:105295. doi: 10.1016/j.nbd.2021.105295.
    PubMed     Abstract available


    January 2021
  13. SENCHUK MM, Van Raamsdonk JM, Moore DJ
    Multiple genetic pathways regulating lifespan extension are neuroprotective in a G2019S LRRK2 nematode model of Parkinson's disease.
    Neurobiol Dis. 2021 Jan 12:105267. doi: 10.1016/j.nbd.2021.105267.
    PubMed     Abstract available


    December 2020
  14. YANG J, Luo S, Zhang J, Yu T, et al
    Exosome-mediated delivery of antisense oligonucleotides targeting alpha-synuclein ameliorates the pathology in a mouse model of Parkinson's disease.
    Neurobiol Dis. 2020 Dec 6:105218. doi: 10.1016/j.nbd.2020.105218.
    PubMed     Abstract available


    November 2020
  15. ARASARATNAM CJ, Singh-Bains MK, Waldvogel HJ, Faull RLM, et al
    Neuroimaging and neuropathology studies of X-linked dystonia parkinsonism.
    Neurobiol Dis. 2020;148:105186.
    PubMed     Abstract available


  16. AGLIARDI C, Meloni M, Guerini FR, Zanzottera M, et al
    Oligomeric alpha-Syn and SNARE complex proteins in peripheral extracellular vesicles of neural origin are biomarkers for Parkinson's disease.
    Neurobiol Dis. 2020 Nov 17:105185. doi: 10.1016/j.nbd.2020.105185.
    PubMed     Abstract available


  17. UNDERWOOD CF, Parr-Brownlie LC
    Primary motor cortex in Parkinson's disease: Functional changes and opportunities for neurostimulation.
    Neurobiol Dis. 2020 Nov 2:105159. doi: 10.1016/j.nbd.2020.105159.
    PubMed     Abstract available


    October 2020
  18. WILKINS KB, Parker JE, Bronte-Stewart HM
    Gait variability is linked to the atrophy of the Nucleus Basalis of Meynert and is resistant to STN DBS in Parkinson's disease.
    Neurobiol Dis. 2020;146:105134.
    PubMed     Abstract available


    September 2020
  19. BAASKE MK, Kormann E, Holt AB, Gulberti A, et al
    Parkinson's disease uncovers an underlying sensitivity of subthalamic nucleus neurons to beta-frequency cortical input in vivo.
    Neurobiol Dis. 2020 Sep 26:105119. doi: 10.1016/j.nbd.2020.105119.
    PubMed     Abstract available


    August 2020
  20. CUTILLO G, Simon DK, Eleuteri S
    VPS35 and the mitochondria: Connecting the dots in Parkinson's disease pathophysiology.
    Neurobiol Dis. 2020 Aug 24:105056. doi: 10.1016/j.nbd.2020.105056.
    PubMed     Abstract available


    July 2020
  21. PETROZZIELLO T, Mills AN, Vaine CA, Penney EB, et al
    Neuroinflammation and histone H3 citrullination are increased in X-linked Dystonia Parkinsonism post-mortem prefrontal cortex.
    Neurobiol Dis. 2020 Jul 30:105032. doi: 10.1016/j.nbd.2020.105032.
    PubMed     Abstract available


  22. KAM TI, Hinkle JT, Dawson TM, Dawson VL, et al
    Microglia and astrocyte dysfunction in parkinson's disease.
    Neurobiol Dis. 2020 Jul 28:105028. doi: 10.1016/j.nbd.2020.105028.
    PubMed     Abstract available


  23. JOERS V, Masilamoni G, Kempf D, Weiss AR, et al
    Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson's disease: A case series.
    Neurobiol Dis. 2020 Jul 23:105027. doi: 10.1016/j.nbd.2020.105027.
    PubMed     Abstract available


  24. WIEST C, Tinkhauser G, Pogosyan A, Bange M, et al
    Local field potential activity dynamics in response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease.
    Neurobiol Dis. 2020 Jul 15:105019. doi: 10.1016/j.nbd.2020.105019.
    PubMed     Abstract available


  25. LAZAROV E, Hillebrand M, Schroder S, Ternka K, et al
    Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity.
    Neurobiol Dis. 2020 Jul 9:105012. doi: 10.1016/j.nbd.2020.105012.
    PubMed     Abstract available


    June 2020
  26. ZHENG C, Xu Y, Chen G, Tan Y, et al
    Distinct anti-dyskinetic effects of amantadine and group II metabotropic glutamate receptor agonist LY354740 in a rodent model: An electrophysiological perspective.
    Neurobiol Dis. 2020;139:104807.
    PubMed     Abstract available


  27. PELLEGRINI C, Ippolito C, Segnani C, Dolfi A, et al
    Pathological remodelling of colonic wall following dopaminergic nigrostriatal neurodegeneration.
    Neurobiol Dis. 2020;139:104821.
    PubMed     Abstract available


  28. ANAND N, Holcom A, Broussalian M, Schmidt M, et al
    Dysregulated iron metabolism in C. elegans catp-6/ATP13A2 mutant impairs mitochondrial function.
    Neurobiol Dis. 2020;139:104786.
    PubMed     Abstract available


    May 2020
  29. HEATON GR, Landeck N, Mamais A, Nalls MA, et al
    Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis.
    Neurobiol Dis. 2020 May 17:104948. doi: 10.1016/j.nbd.2020.104948.
    PubMed     Abstract available


  30. HARJUHAAHTO S, Rasila TS, Molchanova SM, Woldegebriel R, et al
    ALS and Parkinson's disease genes CHCHD10 and CHCHD2 modify synaptic transcriptomes in human IPSC-derived motor neurons.
    Neurobiol Dis. 2020 May 8:104940. doi: 10.1016/j.nbd.2020.104940.
    PubMed     Abstract available


  31. ESPADAS I, Keifman E, Palomo-Garo C, Burgaz S, et al
    Beneficial effects of the phytocannabinoid Delta(9)-THCV in L-DOPA-induced dyskinesia in Parkinson's disease.
    Neurobiol Dis. 2020 May 5:104892. doi: 10.1016/j.nbd.2020.104892.
    PubMed     Abstract available


  32. FAUSTINI G, Longhena F, Bruno A, Bono F, et al
    Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate.
    Neurobiol Dis. 2020;138:104789.
    PubMed     Abstract available


    April 2020
  33. BENOIT SM, Xu H, Schmid S, Alexandrova R, et al
    Expanding the search for genetic biomarkers of Parkinson's disease into the living brain.
    Neurobiol Dis. 2020 Apr 14:104872. doi: 10.1016/j.nbd.2020.104872.
    PubMed     Abstract available


  34. VINUEZA-GAVILANES R, Inigo-Marco I, Larrea L, Lasa M, et al
    N-terminal acetylation mutants affect alpha-synuclein stability, protein levels and neuronal toxicity.
    Neurobiol Dis. 2020;137:104781.
    PubMed     Abstract available


  35. BAASKE MK, Kramer ER, Meka DP, Engler G, et al
    Parkin deficiency perturbs striatal circuit dynamics.
    Neurobiol Dis. 2020;137:104737.
    PubMed     Abstract available


    March 2020
  36. MOREAU C, Rolland AS, Pioli E, Li Q, et al
    Intraventricular dopamine infusion alleviates motor symptoms in a primate model of Parkinson's disease.
    Neurobiol Dis. 2020 Mar 20:104846. doi: 10.1016/j.nbd.2020.104846.
    PubMed     Abstract available


  37. PEREIRA JB, Hall S, Jalakas M, Grothe MJ, et al
    Longitudinal degeneration of the basal forebrain predicts subsequent dementia in Parkinson's disease.
    Neurobiol Dis. 2020 Mar 4:104831. doi: 10.1016/j.nbd.2020.104831.
    PubMed     Abstract available


    February 2020
  38. AMAN JE, Johnson LA, Sanabria DE, Wang J, et al
    Directional deep brain stimulation leads reveal spatially distinct oscillatory activity in the globus pallidus internus of Parkinson's disease patients.
    Neurobiol Dis. 2020 Feb 20:104819. doi: 10.1016/j.nbd.2020.104819.
    PubMed     Abstract available


  39. FAIVRE F, Sanchez-Catalan MJ, Dovero S, Bido S, et al
    Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease.
    Neurobiol Dis. 2020 Feb 19:104818. doi: 10.1016/j.nbd.2020.104818.
    PubMed     Abstract available


  40. STOYKA LE, Arrant AE, Thrasher DR, Russell DL, et al
    Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded alpha-synuclein inclusions.
    Neurobiol Dis. 2020;134:104708.
    PubMed     Abstract available


  41. AFGHAH Z, Chen X, Geiger JD
    Role of endolysosomes and inter-organellar signaling in brain disease.
    Neurobiol Dis. 2020;134:104670.
    PubMed     Abstract available


  42. CHEN C, Vincent AE, Blain AP, Smith AL, et al
    Investigation of mitochondrial biogenesis defects in single substantia nigra neurons using post-mortem human tissues.
    Neurobiol Dis. 2020;134:104631.
    PubMed     Abstract available


  43. ALBERQUILLA S, Gonzalez-Granillo A, Martin ED, Moratalla R, et al
    Dopamine regulates spine density in striatal projection neurons in a concentration-dependent manner.
    Neurobiol Dis. 2020;134:104666.
    PubMed     Abstract available


  44. SOLTI K, Kuan WL, Forizs B, Kustos G, et al
    DJ-1 can form beta-sheet structured aggregates that co-localize with pathological amyloid deposits.
    Neurobiol Dis. 2020;134:104629.
    PubMed     Abstract available


  45. YANG SY, Gegg M, Chau D, Schapira A, et al
    Glucocerebrosidase activity, cathepsin D and monomeric alpha-synuclein interactions in a stem cell derived neuronal model of a PD associated GBA1 mutation.
    Neurobiol Dis. 2020;134:104620.
    PubMed     Abstract available


  46. MEZIAS C, Rey N, Brundin P, Raj A, et al
    Neural connectivity predicts spreading of alpha-synuclein pathology in fibril-injected mouse models: Involvement of retrograde and anterograde axonal propagation.
    Neurobiol Dis. 2020;134:104623.
    PubMed     Abstract available


  47. CRESTO N, Gaillard MC, Gardier C, Gubinelli F, et al
    The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo.
    Neurobiol Dis. 2020;134:104614.
    PubMed     Abstract available


    January 2020
  48. BANDRES-CIGA S, Diez-Fairen M, Kim JJ, Singleton AB, et al
    Genetics of Parkinson's disease: An introspection of its journey towards precision medicine.
    Neurobiol Dis. 2020 Jan 25:104782. doi: 10.1016/j.nbd.2020.104782.
    PubMed     Abstract available


  49. SCHWAB AD, Thurston MJ, Machhi J, Olson KE, et al
    Immunotherapy for Parkinson's disease.
    Neurobiol Dis. 2020;137:104760.
    PubMed     Abstract available


  50. HULME H, Fridjonsdottir E, Gunnarsdottir H, Vallianatou T, et al
    Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy.
    Neurobiol Dis. 2020 Jan 9:104738. doi: 10.1016/j.nbd.2020.104738.
    PubMed     Abstract available


  51. AIME P, Karuppagounder SS, Rao A, Chen Y, et al
    The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson's disease.
    Neurobiol Dis. 2020 Jan 3:104725. doi: 10.1016/j.nbd.2019.104725.
    PubMed     Abstract available


    December 2019
  52. MARMOR O, Rappel P, Valsky D, Bick AS, et al
    Movement context modulates neuronal activity in motor and limbic-associative domains of the human parkinsonian subthalamic nucleus.
    Neurobiol Dis. 2019;136:104716.
    PubMed     Abstract available


  53. HENDERSON MX, Covell DJ, Chung CH, Pitkin RM, et al
    Characterization of novel conformation-selective alpha-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease.
    Neurobiol Dis. 2019 Dec 11:104712. doi: 10.1016/j.nbd.2019.104712.
    PubMed     Abstract available


  54. CHEN Z, Li G, Liu J
    Autonomic dysfunction in Parkinson's disease: Implications for pathophysiology, diagnosis, and treatment.
    Neurobiol Dis. 2019 Dec 3:104700. doi: 10.1016/j.nbd.2019.104700.
    PubMed     Abstract available


    November 2019
  55. SIKORA J, Kieffer BL, Paoletti P, Ouagazzal AM, et al
    Synaptic zinc contributes to motor and cognitive deficits in 6-hydroxydopamine mouse models of Parkinson's disease.
    Neurobiol Dis. 2019;134:104681.
    PubMed     Abstract available


  56. GIANGRASSO DM, Furlong TM, Keefe KA
    Characterization of striatum-mediated behavior and neurochemistry in the DJ-1 knock-out rat model of Parkinson's disease.
    Neurobiol Dis. 2019 Nov 14:104673. doi: 10.1016/j.nbd.2019.104673.
    PubMed     Abstract available


  57. MAASS F, Michalke B, Willkommen D, Leha A, et al
    Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease.
    Neurobiol Dis. 2019 Nov 13:104677. doi: 10.1016/j.nbd.2019.104677.
    PubMed     Abstract available


  58. BELVISI D, Pellicciari R, Fabbrini G, Tinazzi M, et al
    Modifiable risk and protective factors in disease development, progression and clinical subtypes of Parkinson's disease: What do prospective studies suggest?
    Neurobiol Dis. 2019;134:104671.
    PubMed     Abstract available


  59. MILLOT M, Saga Y, Duperrier S, Metereau E, et al
    Prior MDMA administration aggravates MPTP-induced Parkinsonism in macaque monkeys.
    Neurobiol Dis. 2019 Nov 2:104643. doi: 10.1016/j.nbd.2019.104643.
    PubMed     Abstract available


    October 2019
  60. AFLAKI E, Stubblefield BK, McGlinchey RP, McMahon B, et al
    A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson's disease.
    Neurobiol Dis. 2019 Oct 26:104647. doi: 10.1016/j.nbd.2019.104647.
    PubMed     Abstract available


  61. ROCHA EM, De Miranda BR, Castro S, Drolet R, et al
    LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease.
    Neurobiol Dis. 2019 Oct 13:104626. doi: 10.1016/j.nbd.2019.104626.
    PubMed     Abstract available


    September 2019
  62. CHEN CC, Yeh CH, Chan HL, Chang YJ, et al
    Subthalamic nucleus oscillations correlate with vulnerability to freezing of gait in patients with Parkinson's disease.
    Neurobiol Dis. 2019 Sep 5:104605. doi: 10.1016/j.nbd.2019.104605.
    PubMed     Abstract available


  63. RUSSO I, Kaganovich A, Ding J, Landeck N, et al
    Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with alpha-synuclein fibrils.
    Neurobiol Dis. 2019;129:67-78.
    PubMed     Abstract available


  64. FENYI A, Leclair-Visonneau L, Clairembault T, Coron E, et al
    Detection of alpha-synuclein aggregates in gastrointestinal biopsies by protein misfolding cyclic amplification.
    Neurobiol Dis. 2019;129:38-43.
    PubMed     Abstract available


    August 2019
  65. CHATTERJEE D, Kordower JH
    Immunotherapy in Parkinson's disease: Current status and future directions.
    Neurobiol Dis. 2019 Aug 24:104587. doi: 10.1016/j.nbd.2019.104587.
    PubMed     Abstract available


  66. CALABRESI P, Standaert DG
    Dystonia and levodopa-induced dyskinesias in Parkinson's disease: Is there a connection?
    Neurobiol Dis. 2019;132:104579.
    PubMed     Abstract available


  67. DUTTA D, Kundu M, Mondal S, Roy A, et al
    RANTES-induced invasion of Th17 cells into substantia nigra potentiates dopaminergic cell loss in MPTP mouse model of Parkinson's disease.
    Neurobiol Dis. 2019;132:104575.
    PubMed     Abstract available


  68. YOO SW, Oh YS, Hwang EJ, Ryu DW, et al
    "Depressed" caudate and ventral striatum dopamine transporter availability in de novo Depressed Parkinson's disease.
    Neurobiol Dis. 2019 Aug 1:104563. doi: 10.1016/j.nbd.2019.104563.
    PubMed     Abstract available


  69. STEFANI A, Galati S
    PPN-DBS: A utopic vision or a realistic perspective?
    Neurobiol Dis. 2019;128:1-2.
    PubMed    


  70. STEFANI A, Grandi LC, Galati S
    Deep brain stimulation of the pedunculopontine nucleus modulates subthalamic pathological oscillations.
    Neurobiol Dis. 2019;128:49-52.
    PubMed     Abstract available


  71. GUT NK, Mena-Segovia J
    Dichotomy between motor and cognitive functions of midbrain cholinergic neurons.
    Neurobiol Dis. 2019;128:59-66.
    PubMed     Abstract available


  72. NOWACKI A, Galati S, Ai-Schlaeppi J, Bassetti C, et al
    Pedunculopontine nucleus: An integrative view with implications on Deep Brain Stimulation.
    Neurobiol Dis. 2019;128:75-85.
    PubMed     Abstract available


  73. DI GIOVANNI G, Chagraoui A, Puginier E, Galati S, et al
    Reciprocal interaction between monoaminergic systems and the pedunculopontine nucleus: Implication in the mechanism of L-DOPA.
    Neurobiol Dis. 2019;128:9-18.
    PubMed     Abstract available


  74. GARCIA-RILL E, Mahaffey S, Hyde JR, Urbano FJ, et al
    Bottom-up gamma maintenance in various disorders.
    Neurobiol Dis. 2019;128:31-39.
    PubMed     Abstract available


    July 2019
  75. BURBULLA LF, Krainc D
    The role of dopamine in the pathogenesis of GBA1-linked Parkinson's disease.
    Neurobiol Dis. 2019 Jul 25:104545. doi: 10.1016/j.nbd.2019.104545.
    PubMed     Abstract available


  76. CICCHETTI F, David LS, Siddu A, Denis HL, et al
    Cysteamine as a novel disease-modifying compound for Parkinson's disease: Over a decade of research supporting a clinical trial.
    Neurobiol Dis. 2019 Jul 10:104530. doi: 10.1016/j.nbd.2019.104530.
    PubMed     Abstract available


  77. SHEHADEH J, Double KL, Murphy KE, Bobrovskaya L, et al
    Expression of tyrosine hydroxylase isoforms and phosphorylation at serine 40 in the human nigrostriatal system in Parkinson's disease.
    Neurobiol Dis. 2019 Jul 2:104524. doi: 10.1016/j.nbd.2019.104524.
    PubMed     Abstract available


  78. SINCLAIR NC, McDermott HJ, Fallon JB, Perera T, et al
    Deep brain stimulation for Parkinson's disease modulates high-frequency evoked and spontaneous neural activity.
    Neurobiol Dis. 2019 Jul 2:104522. doi: 10.1016/j.nbd.2019.104522.
    PubMed     Abstract available


  79. FISCHER P, Pogosyan A, Green AL, Aziz TZ, et al
    Beta synchrony in the cortico-basal ganglia network during regulation of force control on and off dopamine.
    Neurobiol Dis. 2019;127:253-263.
    PubMed     Abstract available


    June 2019
  80. MARIANI LL, Longueville S, Girault JA, Herve D, et al
    Differential enhancement of ERK, PKA and Ca(2+) signaling in direct and indirect striatal neurons of Parkinsonian mice.
    Neurobiol Dis. 2019 Jun 17:104506. doi: 10.1016/j.nbd.2019.104506.
    PubMed     Abstract available


    May 2019
  81. BOOTH HDE, Wessely F, Connor-Robson N, Rinaldi F, et al
    RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes.
    Neurobiol Dis. 2019 May 11. pii: S0969-9961(19)30120.
    PubMed     Abstract available


  82. SHETTY AS, Bhatia KP, Lang AE
    Dystonia and Parkinson's disease: What is the relationship?
    Neurobiol Dis. 2019 May 9. pii: S0969-9961(19)30107.
    PubMed     Abstract available


    April 2019
  83. CHOI DJ, An J, Jou I, Park SM, et al
    A Parkinson's disease gene, DJ-1, regulates anti-inflammatory roles of astrocytes through prostaglandin D2 synthase expression.
    Neurobiol Dis. 2019;127:482-491.
    PubMed     Abstract available


    March 2019
  84. LOFREDI R, Tan H, Neumann WJ, Yeh CH, et al
    Beta bursts during continuous movements accompany the velocity decrement in Parkinson's disease patients.
    Neurobiol Dis. 2019 Mar 18. pii: S0969-9961(19)30068.
    PubMed     Abstract available


  85. SAMPSON T
    The impact of indigenous microbes on Parkinson's disease.
    Neurobiol Dis. 2019 Mar 15. pii: S0969-9961(19)30069.
    PubMed     Abstract available


    February 2019
  86. SHAHID M, Kim J, Leaver K, Hendershott T, et al
    An increased rate of longitudinal cognitive decline is observed in Parkinson's disease patients with low CSF Ass42 and an APOE epsilon4 allele.
    Neurobiol Dis. 2019 Feb 28. pii: S0969-9961(18)30655.
    PubMed     Abstract available


  87. KIRKLEY KS, Popichak KA, Hammond SL, Davies C, et al
    Genetic suppression of IKK2/NF-kappaB in astrocytes inhibits neuroinflammation and reduces neuronal loss in the MPTP-Probenecid model of Parkinson's disease.
    Neurobiol Dis. 2019 Feb 25. pii: S0969-9961(19)30050.
    PubMed     Abstract available


  88. SABIR MS, Blauwendraat C, Ahmed S, Serrano GE, et al
    Assessment of APOE in atypical parkinsonism syndromes.
    Neurobiol Dis. 2019 Feb 21. pii: S0969-9961(19)30046.
    PubMed     Abstract available


  89. MEIDAHL AC, Moll CKE, van Wijk B, Gulberti A, et al
    Synchronised spiking activity underlies phase amplitude coupling in the subthalamic nucleus of Parkinson's disease patients.
    Neurobiol Dis. 2019 Feb 9. pii: S0969-9961(19)30037.
    PubMed     Abstract available


    January 2019
  90. BADEN P, Yu C, Deleidi M
    Insights into GBA Parkinson's disease pathology and therapy with induced pluripotent stem cell model systems.
    Neurobiol Dis. 2019 Jan 31. pii: S0969-9961(19)30032.
    PubMed     Abstract available


  91. GLAAB E, Trezzi JP, Greuel A, Jager C, et al
    Integrative analysis of blood metabolomics and PET brain neuroimaging data for Parkinson's disease.
    Neurobiol Dis. 2019 Jan 9. pii: S0969-9961(19)30002.
    PubMed     Abstract available


  92. MELLONE M, Zianni E, Stanic J, Campanelli F, et al
    NMDA receptor GluN2D subunit participates to levodopa-induced dyskinesia pathophysiology.
    Neurobiol Dis. 2019;121:338-349.
    PubMed     Abstract available


  93. GUNDNER AL, Duran-Pacheco G, Zimmermann S, Ruf I, et al
    Path mediation analysis reveals GBA impacts Lewy body disease status by increasing alpha-synuclein levels.
    Neurobiol Dis. 2019;121:205-213.
    PubMed     Abstract available


    December 2018
  94. DODIYA HB, Forsyth CB, Voigt RM, Engen PA, et al
    Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease.
    Neurobiol Dis. 2018 Dec 20. pii: S0969-9961(18)30768.
    PubMed     Abstract available


  95. MUS L, Siani F, Giuliano C, Ghezzi C, et al
    Development and biochemical characterization of a mouse model of Parkinson's disease bearing defective glucocerebrosidase activity.
    Neurobiol Dis. 2018 Dec 3. pii: S0969-9961(18)30756.
    PubMed     Abstract available


    November 2018
  96. HUANG YR, Xie XX, Ji M, Yu XL, et al
    Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease.
    Neurobiol Dis. 2018 Nov 24. pii: S0969-9961(18)30401.
    PubMed     Abstract available


  97. CHO SS, Christopher L, Koshimori Y, Li C, et al
    Decreased pallidal vesicular monoamine transporter type 2 availability in Parkinson's disease: The contribution of the nigropallidal pathway.
    Neurobiol Dis. 2018;124:176-182.
    PubMed     Abstract available


  98. REED X, Bandres-Ciga S, Blauwendraat C, Cookson MR, et al
    The role of monogenic genes in idiopathic Parkinson's disease.
    Neurobiol Dis. 2018 Nov 15. pii: S0969-9961(18)30668.
    PubMed     Abstract available


  99. IKEDA-MATSUO Y, Miyata H, Mizoguchi T, Ohama E, et al
    Microsomal prostaglandin E synthase-1 is a critical factor in dopaminergic neurodegeneration in Parkinson's disease.
    Neurobiol Dis. 2018 Nov 10. pii: S0969-9961(18)30741.
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  100. SAMPEDRO F, Marin-Lahoz J, Martinez-Horta S, Pagonabarraga J, et al
    Dopaminergic degeneration induces early posterior cortical thinning in Parkinson's disease.
    Neurobiol Dis. 2018 Nov 5. pii: S0969-9961(18)30544.
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  101. LAMONTAGNE-PROULX J, St-Amour I, Labib R, Pilon J, et al
    Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease.
    Neurobiol Dis. 2018 Nov 5. pii: S0969-9961(18)30534.
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  102. MILOSEVIC L, Gramer R, Kim TH, Algarni M, et al
    Modulation of inhibitory plasticity in basal ganglia output nuclei of patients with Parkinson's disease.
    Neurobiol Dis. 2018 Nov 1. pii: S0969-9961(18)30593.
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    October 2018
  103. WEIHOFEN A, Liu Y, Arndt JW, Huy C, et al
    Development of an aggregate-selective, human-derived alpha-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.
    Neurobiol Dis. 2018 Oct 28. pii: S0969-9961(18)30448.
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  104. HERNANDO S, Requejo C, Herran E, Ruiz-Ortega JA, et al
    Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation.
    Neurobiol Dis. 2018 Oct 5. pii: S0969-9961(18)30292.
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    September 2018
  105. SOYAL SM, Zara G, Ferger B, Felder TK, et al
    The PPARGC1A locus and CNS-specific PGC-1alpha isoforms are associated with Parkinson's Disease.
    Neurobiol Dis. 2018 Sep 17. pii: S0969-9961(18)30591.
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  106. PINA-FUENTES D, van Zijl JC, van Dijk JMC, Little S, et al
    The characteristics of pallidal low-frequency and beta bursts could help implementing adaptive brain stimulation in the parkinsonian and dystonic internal globus pallidus.
    Neurobiol Dis. 2018 Sep 15. pii: S0969-9961(18)30391.
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  107. MAMMADOVA N, Summers CM, Kokemuller RD, He Q, et al
    Accelerated accumulation of retinal alpha-synuclein (pSer129) and tau, neuroinflammation and autophagic dysregulation in a seeded mouse model of Parkinson's disease.
    Neurobiol Dis. 2018 Sep 12. pii: S0969-9961(18)30204.
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  108. ANIDI CM, O'Day JJ, Anderson RW, Afzal MF, et al
    Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease.
    Neurobiol Dis. 2018 Sep 6. pii: S0969-9961(18)30548.
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    August 2018
  109. TUBERT C, Galtieri D, James Surmeier D
    The pedunclopontine nucleus and Parkinson's disease.
    Neurobiol Dis. 2018 Aug 29. pii: S0969-9961(18)30493.
    PubMed     Abstract available


  110. MOLONEY EB, Moskites A, Ferrari EJ, Isacson O, et al
    The glycoprotein GPNMB is selectively elevated in the substantia nigra of Parkinson's disease patients and increases after lysosomal stress.
    Neurobiol Dis. 2018 Aug 24. pii: S0969-9961(18)30484.
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  111. GOETZ L, Piallat B, Bhattacharjee M, Mathieu H, et al
    Spike discharge characteristic of the caudal mesencephalic reticular formation and pedunculopontine nucleus in MPTP-induced primate model of Parkinson disease.
    Neurobiol Dis. 2018 Aug 4. pii: S0969-9961(18)30394.
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    June 2018
  112. THEVATHASAN W, Moro E
    What is the therapeutic mechanism of pedunculopontine nucleus stimulation in Parkinson's disease?
    Neurobiol Dis. 2018 Jun 19. pii: S0969-9961(18)30193.
    PubMed     Abstract available


  113. TINKHAUSER G, Torrecillos F, Duclos Y, Tan H, et al
    Beta burst coupling across the motor circuit in Parkinson's disease.
    Neurobiol Dis. 2018 Jun 14. pii: S0969-9961(18)30182.
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  114. TOZZI A, Durante V, Bastioli G, Mazzocchetti P, et al
    Dopamine D2 receptor activation potently inhibits striatal glutamatergic transmission in a G2019S LRRK2 genetic model of Parkinson's disease.
    Neurobiol Dis. 2018 Jun 13. pii: S0969-9961(18)30185.
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    May 2018
  115. POLAR CA, Gupta R, Lehmkuhle MJ, Dorval AD, et al
    Correlation between cortical beta power and gait speed is suppressed in a parkinsonian model, but restored by therapeutic deep brain stimulation.
    Neurobiol Dis. 2018 May 30. pii: S0969-9961(18)30151.
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    April 2018
  116. PAN PY, Zhu Y, Shen Y, Yue Z, et al
    Crosstalk between presynaptic trafficking and autophagy in Parkinson's disease.
    Neurobiol Dis. 2018 Apr 30. pii: S0969-9961(18)30136.
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  117. WANG H, Atik A, Stewart T, Ginghina C, et al
    Plasma alpha-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study.
    Neurobiol Dis. 2018 Apr 26. pii: S0969-9961(18)30123.
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  118. ANDERSEN MA, Christensen KV, Badolo L, Smith GP, et al
    Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-alpha-synuclein is normalized by LRRK2 modulation.
    Neurobiol Dis. 2018 Apr 19. pii: S0969-9961(18)30119.
    PubMed     Abstract available


  119. DE MIRANDA BR, Rocha EM, Bai Q, El Ayadi A, et al
    Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson's disease.
    Neurobiol Dis. 2018 Apr 9. pii: S0969-9961(18)30116.
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    March 2018
  120. GLEAVE JA, Arathoon LR, Trinh D, Lizal KE, et al
    Corrigendum to "Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant alpha-synuclein rat model of parkinsonism" [Neurobiol. Dis. 106 (2018) 133-146].
    Neurobiol Dis. 2018 Mar 20. pii: S0969-9961(18)30054.
    PubMed    


  121. PITCAIRN C, Wani WY, Mazzulli JR
    Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease.
    Neurobiol Dis. 2018 Mar 14. pii: S0969-9961(18)30074.
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  122. PUSKA G, Lutz MI, Molnar K, Regelsberger G, et al
    Lysosomal response in relation to alpha-synuclein pathology differs between Parkinson's disease and multiple system atrophy.
    Neurobiol Dis. 2018 Mar 2. pii: S0969-9961(18)30061.
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    February 2018
  123. RIZZI N, Brunialti E, Cerri S, Cermisoni G, et al
    In vivo imaging of early signs of dopaminergic neuronal death in an animal model of Parkinson's disease.
    Neurobiol Dis. 2018 Feb 24. pii: S0969-9961(18)30037.
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  124. PIERCE SE, Tyson T, Booms A, Prahl J, et al
    Parkinson's disease genetic risk in a midbrain neuronal cell line.
    Neurobiol Dis. 2018 Feb 24. pii: S0969-9961(18)30039.
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  125. WU HM, Li T, Wang ZF, Huang SS, et al
    Mitochondrial DNA variants modulate genetic susceptibility to Parkinson's disease in Han Chinese.
    Neurobiol Dis. 2018 Feb 24. pii: S0969-9961(18)30047.
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    January 2018
  126. ALCALAY RN, Wolf P, Levy OA, Kang UJ, et al
    Alpha galactosidase A activity in Parkinson's disease.
    Neurobiol Dis. 2018 Jan 21. pii: S0969-9961(18)30018.
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  127. MERCADO G, Castillo V, Soto P, Lopez N, et al
    Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease.
    Neurobiol Dis. 2018 Jan 17. pii: S0969-9961(18)30004.
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  128. SHAROTT A, Gulberti A, Hamel W, Koppen JA, et al
    Spatio-temporal dynamics of cortical drive to human subthalamic nucleus neurons in Parkinson's disease.
    Neurobiol Dis. 2018 Jan 4. pii: S0969-9961(18)30001.
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  129. ALDRIN-KIRK P, Heuer A, Rylander Ottosson D, Davidsson M, et al
    Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum.
    Neurobiol Dis. 2018;109.
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    December 2017
  130. NELSON MP, Boutin M, Tse TE, Lu H, et al
    The lysosomal enzyme alpha-Galactosidase A is deficient in Parkinson's disease brain in association with the pathologic accumulation of alpha-synuclein.
    Neurobiol Dis. 2017;110:68-81.
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    October 2017
  131. SPIGOLON G, Cavaccini A, Trusel M, Tonini R, et al
    cJun N-terminal kinase (JNK) mediates cortico-striatal signaling in a model of Parkinson's disease.
    Neurobiol Dis. 2017 Oct 28. pii: S0969-9961(17)30243.
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    September 2017
  132. SYRKIN-NIKOLAU J, Koop MM, Prieto T, Anidi C, et al
    Subthalamic neural entropy is a feature of freezing of gait in freely moving people with Parkinson's disease.
    Neurobiol Dis. 2017 Sep 7. pii: S0969-9961(17)30214.
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    August 2017
  133. BIOSA A, Sandrelli F, Beltramini M, Greggio E, et al
    Recent findings on the physiological function of DJ-1: Beyond Parkinson's disease.
    Neurobiol Dis. 2017 Aug 17. pii: S0969-9961(17)30186.
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    July 2017
  134. RYDBIRK R, Elfving B, Andersen MD, Langbol MA, et al
    Cytokine profiling in the prefrontal cortex of Parkinson's Disease and Multiple System Atrophy patients.
    Neurobiol Dis. 2017;106:269-278.
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    June 2017
  135. ARATHOON LR, Gleave JA, Trinh D, Lizal KE, et al
    Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant alpha-synuclein rat model of parkinsonism.
    Neurobiol Dis. 2017 Jun 30. pii: S0969-9961(17)30136.
    PubMed     Abstract available


    May 2017
  136. GIESERT F, Glasl L, Zimprich A, Ernst L, et al
    The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse.
    Neurobiol Dis. 2017 May 30. pii: S0969-9961(17)30123.
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    April 2017
  137. JULIENNE H, Buhl E, Leslie DS, Hodge JJL, et al
    Drosophila PINK1 and parkin loss-of-function mutants display a range of non-motor Parkinson's disease phenotypes.
    Neurobiol Dis. 2017 Apr 20. pii: S0969-9961(17)30088.
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  138. CAVALIERE F, Cerf L, Dehay B, Ramos-Gonzalez P, et al
    In vitro alpha-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains.
    Neurobiol Dis. 2017;103:101-112.
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  139. ROCHA EM, De Miranda B, Sanders LH
    Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson's disease.
    Neurobiol Dis. 2017 Apr 8. pii: S0969-9961(17)30080.
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    March 2017
  140. LALOUX C, Gouel F, Lachaud C, Timmerman K, et al
    Continuous cerebroventricular administration of dopamine: A new treatment for severe dyskinesia in Parkinson's disease?
    Neurobiol Dis. 2017 Mar 28. pii: S0969-9961(17)30061.
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    December 2016
  141. SONG L, McMackin M, Nguyen A, Cortopassi G, et al
    Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism.
    Neurobiol Dis. 2016 Dec 29. pii: S0969-9961(16)30314.
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  142. MASILAMONI GJ, Groover O, Smith Y
    Reduced noradrenergic innervation of ventral midbrain dopaminergic cell groups and the subthalamic nucleus in MPTP-treated parkinsonian monkeys.
    Neurobiol Dis. 2016 Dec 29. pii: S0969-9961(16)30315.
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  143. VAINE CA, Shin D, Liu C, Hendriks W, et al
    X-linked Dystonia-Parkinsonism patient cells exhibit altered signaling via nuclear factor-kappa B.
    Neurobiol Dis. 2016 Dec 22. pii: S0969-9961(16)30299.
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  144. GENG X, Zhang J, Jiang Y, Ashkan K, et al
    Comparison of oscillatory activity in subthalamic nucleus in Parkinson's disease and dystonia.
    Neurobiol Dis. 2016;98:100-107.
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  145. KOZINA EA, Kim AR, Kurina AY, Ugrumov MV, et al
    Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism.
    Neurobiol Dis. 2016;98:108-121.
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    September 2016
  146. NKILIZA A, Mutez E, Simonin C, Lepretre F, et al
    RNA-binding disturbances as a continuum from spinocerebellar ataxia type 2 to Parkinson disease.
    Neurobiol Dis. 2016 Sep 20. pii: S0969-9961(16)30230.
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  147. KIRIK D, Cederfjall E, Halliday G, Petersen A, et al
    Gene therapy for Parkinson's disease: Disease modification by GDNF family of ligands.
    Neurobiol Dis. 2016 Sep 8. pii: S0969-9961(16)30222.
    PubMed     Abstract available


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