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Pancreatitis

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 48 articles: HTML format

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July 2021
1. KING ME, Zhang J, Lin JQ, Garza KY, et al
   Rapid diagnosis and tumor margin assessment during pancreatic cancer surgery with the MasSpec Pen technology.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   June 2021
2. YANG Y, Wang H, He J, Shi W, et al
   A single-cell-resolution fate map of endoderm reveals demarcation of pancreatic progenitors by cell cycle.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   May 2021
3. CHENG DK, Oni TE, Thalappillil JS, Park Y, et al
   Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   March 2021
4. TSAI PY, Lee MS, Jadhav U, Naqvi I, et al
   Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   February 2021
5. MOORE AM, Zhou L, Cui J, Li L, et al
   NAD(+) depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   
6. MUKHOPADHYAY S, Biancur DE, Parker SJ, Yamamoto K, et al
   Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   
7. 
   Correction to Supporting Information for Qadir et al., Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed    
   
   
   
8. MUCCIOLO G, Curcio C, Roux C, Li WY, et al
   IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   November 2020
9. GRBOVIC-HUEZO O, Pitter KL, Lecomte N, Saglimbeni J, et al
   Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma.
   Proc Natl Acad Sci U S A. 2020 Nov 16. pii: 1920240117.
   PubMed     Abstract available
   
   
   October 2020
10. BIASCI D, Smoragiewicz M, Connell CM, Wang Z, et al
    CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response.
    Proc Natl Acad Sci U S A. 2020 Oct 30. pii: 2013644117.
    PubMed     Abstract available
    
    
    
11. WANG B, Lin H, Li X, Lu W, et al
    The adaptor protein APPL2 controls glucose-stimulated insulin secretion via F-actin remodeling in pancreatic beta-cells.
    Proc Natl Acad Sci U S A. 2020 Oct 29. pii: 2016997117.
    PubMed     Abstract available
    
    
    
12. WEI X, Yang J, Adair SJ, Ozturk H, et al
    Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells.
    Proc Natl Acad Sci U S A. 2020 Oct 23. pii: 2009899117.
    PubMed     Abstract available
    
    
    May 2020
13. GUPTA R, Malvi P, Parajuli KR, Janostiak R, et al
    KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity.
    Proc Natl Acad Sci U S A. 2020 May 19. pii: 2005156117.
    PubMed     Abstract available
    
    
    
14. SOMERVILLE TDD, Xu Y, Wu XS, Maia-Silva D, et al
    ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2020 May 8. pii: 1921484117.
    PubMed     Abstract available
    
    
    April 2020
15. QADIR MMF, Alvarez-Cubela S, Klein D, van Dijk J, et al
    Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020 Apr 30. pii: 1918314117.
    PubMed     Abstract available
    
    
    
16. GONZALEZ-MORO I, Olazagoitia-Garmendia A, Colli ML, Cobo-Vuilleumier N, et al
    The T1D-associated lncRNA Lnc13 modulates human pancreatic beta cell inflammation by allele-specific stabilization of STAT1 mRNA.
    Proc Natl Acad Sci U S A. 2020 Apr 13. pii: 1914353117.
    PubMed     Abstract available
    
    
    March 2020
17. WASYLISHEN AR, Sun C, Chau GP, Qi Y, et al
    Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress.
    Proc Natl Acad Sci U S A. 2020;117:6622-6629.
    PubMed     Abstract available
    
    
    January 2020
18. PETRENKO V, Gandasi NR, Sage D, Tengholm A, et al
    In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis.
    Proc Natl Acad Sci U S A. 2020 Jan 21. pii: 1916539117.
    PubMed     Abstract available
    
    
    
19. 
    Correction for Porter et al., Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2020 Jan 13. pii: 1922469117.
    PubMed    
    
    
    December 2019
20. PORTER RL, Magnus NKC, Thapar V, Morris R, et al
    Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2019 Dec 16. pii: 1914915116.
    PubMed     Abstract available
    
    
    
21. DRIEHUIS E, van Hoeck A, Moore K, Kolders S, et al
    Pancreatic cancer organoids recapitulate disease and allow personalized drug screening.
    Proc Natl Acad Sci U S A. 2019 Dec 9. pii: 1911273116.
    PubMed     Abstract available
    
    
    October 2019
22. WEN CL, Huang K, Jiang LL, Lu XX, et al
    An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2019 Oct 29. pii: 1914557116.
    PubMed     Abstract available
    
    
    September 2019
23. MAMEISHVILI E, Serafimidis I, Iwaszkiewicz S, Lesche M, et al
    Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.
    Proc Natl Acad Sci U S A. 2019 Sep 23. pii: 1901075116.
    PubMed     Abstract available
    
    
    
24. BINGER KJ, Neukam M, Tattikota SG, Qadri F, et al
    Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic beta cells.
    Proc Natl Acad Sci U S A. 2019 Sep 16. pii: 1903678116.
    PubMed     Abstract available
    
    
    
25. TIAN C, Clauser KR, Ohlund D, Rickelt S, et al
    Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells.
    Proc Natl Acad Sci U S A. 2019 Sep 4. pii: 1908626116.
    PubMed     Abstract available
    
    
    August 2019
26. HASHIMOTO S, Furukawa S, Hashimoto A, Tsutaho A, et al
    ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer.
    Proc Natl Acad Sci U S A. 2019 Aug 9. pii: 1901765116.
    PubMed     Abstract available
    
    
    July 2019
27. TORRES C, Mancinelli G, Cordoba-Chacon J, Viswakarma N, et al
    p110gamma deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity.
    Proc Natl Acad Sci U S A. 2019 Jul 2. pii: 1813012116.
    PubMed     Abstract available
    
    
    June 2019
28. CROTTES D, Lin YT, Peters CJ, Gilchrist JM, et al
    TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis.
    Proc Natl Acad Sci U S A. 2019 Jun 10. pii: 1900703116.
    PubMed     Abstract available
    
    
    March 2019
29. ELLIOTT IA, Dann AM, Xu S, Kim SS, et al
    Lysosome inhibition sensitizes pancreatic cancer to replication stress by aspartate depletion.
    Proc Natl Acad Sci U S A. 2019 Mar 20. pii: 1812410116.
    PubMed     Abstract available
    
    
    January 2019
30. BLANDO J, Sharma A, Higa MG, Zhao H, et al
    Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2019 Jan 11. pii: 1811067116.
    PubMed     Abstract available
    
    
    December 2018
31. HAMDAN FH, Johnsen SA
    DeltaNp63-dependent super enhancers define molecular identity in pancreatic cancer by an interconnected transcription factor network.
    Proc Natl Acad Sci U S A. 2018 Dec 12. pii: 1812915116.
    PubMed     Abstract available
    
    
    August 2018
32. PLUGIS NM, Weng N, Zhao Q, Palanski BA, et al
    Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin.
    Proc Natl Acad Sci U S A. 2018;115:8781-8786.
    PubMed     Abstract available
    
    
    April 2018
33. JIAN X, Felsenfeld G
    Insulin promoter in human pancreatic beta cells contacts diabetes susceptibility loci and regulates genes affecting insulin metabolism.
    Proc Natl Acad Sci U S A. 2018 Apr 30. pii: 1803146115.
    PubMed     Abstract available
    
    
    
34. TAMURA K, Yu J, Hata T, Suenaga M, et al
    Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer.
    Proc Natl Acad Sci U S A. 2018 Apr 18. pii: 1720588115.
    PubMed     Abstract available
    
    
    
35. OROZCO CA, Martinez-Bosch N, Guerrero PE, Vinaixa J, et al
    Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.
    Proc Natl Acad Sci U S A. 2018 Apr 3. pii: 1722434115.
    PubMed     Abstract available
    
    
    March 2018
36. MA H, Wert KJ, Shvartsman D, Melton DA, et al
    Establishment of human pluripotent stem cell-derived pancreatic beta-like cells in the mouse pancreas.
    Proc Natl Acad Sci U S A. 2018 Mar 29. pii: 1702059115.
    PubMed     Abstract available
    
    
    January 2018
37. DJUREC M, Grana O, Lee A, Troule K, et al
    Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.
    Proc Natl Acad Sci U S A. 2018 Jan 19. pii: 1717802115.
    PubMed     Abstract available
    
    
    November 2017
38. CARRERO JA, McCarthy DP, Ferris ST, Wan X, et al
    Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice.
    Proc Natl Acad Sci U S A. 2017 Nov 13. pii: 201713543.
    PubMed     Abstract available
    
    
    October 2017
39. RIBEIRO D, Horvath I, Heath N, Hicks R, et al
    Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation.
    Proc Natl Acad Sci U S A. 2017 Oct 2. pii: 201711389.
    PubMed     Abstract available
    
    
    September 2017
40. COHEN JD, Javed AA, Thoburn C, Wong F, et al
    Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers.
    Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201704961.
    PubMed     Abstract available
    
    
    August 2017
41. VLAHOS AE, Cober N, Sefton MV
    Modular tissue engineering for the vascularization of subcutaneously transplanted pancreatic islets.
    Proc Natl Acad Sci U S A. 2017 Aug 16. pii: 201619216.
    PubMed     Abstract available
    
    
    July 2017
42. 
    Correction for Li et al., Targeting reactive nitrogen species suppresses hereditary pancreatic cancer.
    Proc Natl Acad Sci U S A. 2017 Jul 17. pii: 201711704.
    PubMed    
    
    
    June 2017
43. LI M, Chen Q, Ma T, Yu X, et al
    Targeting reactive nitrogen species suppresses hereditary pancreatic cancer.
    Proc Natl Acad Sci U S A. 2017 Jun 19. pii: 201702156.
    PubMed     Abstract available
    
    
    May 2017
44. SHEN J, Ha DP, Zhu G, Rangel DF, et al
    GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice.
    Proc Natl Acad Sci U S A. 2017 May 1. pii: 201616060.
    PubMed     Abstract available
    
    
    April 2017
45. HAO W, Komar HM, Hart PA, Conwell DL, et al
    Mathematical model of chronic pancreatitis.
    Proc Natl Acad Sci U S A. 2017 Apr 24. pii: 201620264.
    PubMed     Abstract available
    
    
    January 2017
46. SHERMAN MH, Yu RT, Tseng TW, Sousa CM, et al
    Stromal cues regulate the pancreatic cancer epigenome and metabolome.
    Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201620164.
    PubMed     Abstract available
    
    
    December 2016
47. DEMIR IE, Kujundzic K, Pfitzinger PL, Saricaoglu OC, et al
    Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells.
    Proc Natl Acad Sci U S A. 2016 Dec 16. pii: 201606909.
    PubMed     Abstract available
    
    
    September 2016
48. SONCINI M, Corna G, Moresco M, Coltella N, et al
    24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development.
    Proc Natl Acad Sci U S A. 2016 Sep 26. pii: 201613332.
    PubMed     Abstract available
    
    

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