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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 26 articles:
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Single Articles


    May 2026
  1. TESTA E, Dezi C, Lovat F, Piro G, et al
    Fra-2 controls the response to the KRAS inhibitor MRTX-1133 in pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2026;123:e2601788123.
    PubMed     Abstract available


  2. MILCAREK AT, Yeon M, Esposito C, Kulkarni P, et al
    Mitochondrial double-stranded RNA fuels pancreatic cancer growth via RIG-I/TLR3 inflammation.
    Proc Natl Acad Sci U S A. 2026;123:e2528281123.
    PubMed     Abstract available



  3. Retraction for Liaki et al., A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance.
    Proc Natl Acad Sci U S A. 2026;123:e2612385123.
    PubMed    


    March 2026
  4. RAMSEY EL, Dobersch S, Freie B, Hong NH, et al
    MondoA mediates transcriptional coordination between the MYC network and the integrated stress response in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2524659123.
    PubMed     Abstract available


    February 2026
  5. ZHAO H, Chen H, Kang Z, Huang X, et al
    Genetic recording of pancreatic beta cell proliferation.
    Proc Natl Acad Sci U S A. 2026;123:e2507877123.
    PubMed     Abstract available


    January 2026
  6. ANTONUCCI L, Watari K, Feng Y, Qi J, et al
    Selective targeting of NRF2-high pancreatic ductal adenocarcinoma with an NQO1-activatable prodrug.
    Proc Natl Acad Sci U S A. 2026;123:e2511733123.
    PubMed     Abstract available


  7. LU H, Liu Y, Chiang HY, Zhang H, et al
    Exploring the interplay between protein conformational changes and phosphorylation in a pancreatic cancer cell and stellate cell coculture system.
    Proc Natl Acad Sci U S A. 2026;123:e2511839122.
    PubMed     Abstract available


    December 2025
  8. LIAKI V, Barrambana S, Kostopoulou M, Lechuga CG, et al
    A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance.
    Proc Natl Acad Sci U S A. 2025;122:e2523039122.
    PubMed     Abstract available


    November 2025
  9. LI YR, Shen X, Zhu E, Li Z, et al
    Targeting orthotopic and metastatic pancreatic cancer with allogeneic stem cell-engineered mesothelin-redirected CAR-NKT cells.
    Proc Natl Acad Sci U S A. 2025;122:e2517786122.
    PubMed     Abstract available


  10. YANG X, Wang Y, Zhou J, Li S, et al
    Engineering a spatiotemporal macrophage circuit via STING phase separation to override immune suppression in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2504718122.
    PubMed     Abstract available


    September 2025
  11. CHUANG PK, Chung C, Liao KS, Wong CH, et al
    Improving the efficacy of anti-SSEA4 antibody in pancreatic cancer immunotherapy with glyco-optimization and immune checkpoint blockade.
    Proc Natl Acad Sci U S A. 2025;122:e2517415122.
    PubMed     Abstract available


    August 2025
  12. YUAN S, Yang X, Bremmer AM, Wang Y, et al
    Programmable immunoprobiotics orchestrate antitumor immune response with Pin1 inhibition for pancreatic cancer treatment.
    Proc Natl Acad Sci U S A. 2025;122:e2507711122.
    PubMed     Abstract available


    July 2025
  13. MORESCO P, Kastan JP, Yang JI, Prabakar R, et al
    Signal peptide-independent secretion of keratin-19 by pancreatic cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2426218122.
    PubMed     Abstract available


    April 2025
  14. VINAIXA J, Martinez-Bosch N, Gibert J, Manero-Ruperez N, et al
    Nuclear Galectin-1 promotes KRAS-dependent activation of pancreatic cancer stellate cells.
    Proc Natl Acad Sci U S A. 2025;122:e2424051122.
    PubMed     Abstract available


    March 2025
  15. ZHU Q, Yu C, Chen Y, Luo W, et al
    Dual mRNA nanoparticles strategy for enhanced pancreatic cancer treatment and beta-elemene combination therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2418306122.
    PubMed     Abstract available


    October 2024
  16. YANG Y, Wang B, Dong H, Lin H, et al
    The mitochondrial enzyme pyruvate carboxylase restricts pancreatic beta-cell senescence by blocking p53 activation.
    Proc Natl Acad Sci U S A. 2024;121:e2401218121.
    PubMed     Abstract available


    August 2024
  17. KITAMURA RA, Hummel D, Ustione A, Piston DW, et al
    Dual role of neuroplastin in pancreatic beta cells: Regulating insulin secretion and promoting islet inflammation.
    Proc Natl Acad Sci U S A. 2024;121:e2411234121.
    PubMed     Abstract available


  18. SU W, Kochen Rossi J, Nuevo-Tapioles C, Chen T, et al
    UPF1 deficiency enhances mitochondrial ROS which promotes an immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2024;121:e2401996121.
    PubMed     Abstract available


    July 2024
  19. AMIT U, Uslu U, Verginadis II, Kim MM, et al
    Proton radiation boosts the efficacy of mesothelin-targeting chimeric antigen receptor T cell therapy in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2403002121.
    PubMed     Abstract available


  20. LI J, Moresco P, Fearon DT
    Intratumoral NKT cell accumulation promotes antitumor immunity in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2403917121.
    PubMed     Abstract available


    April 2024
  21. HIYOSHI H, Sakuma K, Asano S, Napier SC, et al
    Identification and removal of unexpected proliferative off-target cells emerging after iPSC-derived pancreatic islet cell implantation.
    Proc Natl Acad Sci U S A. 2024;121:e2320883121.
    PubMed     Abstract available


  22. MURTHY D, Attri KS, Suresh V, Rajacharya GH, et al
    The MUC1-HIF-1alpha signaling axis regulates pancreatic cancer pathogenesis through polyamine metabolism remodeling.
    Proc Natl Acad Sci U S A. 2024;121:e2315509121.
    PubMed     Abstract available


    August 2023
  23. DASGUPTA A, Gibbard DF, Schmitt RE, Arneson-Wissink PC, et al
    A TGF-beta/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2023;120:e2215095120.
    PubMed     Abstract available


    May 2023
  24. CHANDA D, Thoudam T, Sinam IS, Lim CW, et al
    Upregulation of the ERRgamma-VDAC1 axis underlies the molecular pathogenesis of pancreatitis.
    Proc Natl Acad Sci U S A. 2023;120:e2219644120.
    PubMed     Abstract available


    March 2023

  25. Correction for Taylor et al., Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.
    Proc Natl Acad Sci U S A. 2023;120:e2302726120.
    PubMed    


  26. MELLO SS, Flowers BM, Mazur PK, Lee JJ, et al
    Multifaceted role for p53 in pancreatic cancer suppression.
    Proc Natl Acad Sci U S A. 2023;120:e2211937120.
    PubMed     Abstract available


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