: The AMEDEO Literature Guide

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Articles published in Pain
Retrieve available abstracts of 656 articles:
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Single Articles

February 2026

LV G, Liu H, Guan Z, Liu L, et al
Inhibition of bladder sensory afferents via intrabladder injection of adenoassociated viruses-retro-mediated Gi-DREADDs alleviates bladder overactivity and pain in mice.
Pain. 2026 Feb 3. doi: 10.1097/j.pain.0000000000003923.
PubMed Abstract available

CHEN SC, Yeh CH
Heuristic bias and modality effects limit salience as a pain biomarker.
Pain. 2026;167:494-495.
PubMed

YEH CH, Chen SC
Emotional neutrality and family strain: reframing chronic pain risk among older African Americans.
Pain. 2026;167:492-493.
PubMed

DAVIS KD
Showcasing scientific discovery in PAIN: an opportunity for authors.
Pain. 2026;167:247-248.
PubMed

RIOS-LEON M, Huidobro-Labarga B, Castillo-Aguilar I, Segura A, et al
Prevalence and characterization of pediatric-onset spinal cord injury pain as reported by youth: an observational and case control association study with TRPA1 gene single nucleotide polymorphisms.
Pain. 2026;167:455-468.
PubMed Abstract available

January 2026

MURRAY CB, Goldstein SP, Palermo TM
Optimizing engagement in digital behavioral interventions for chronic pain: challenges and opportunities.
Pain. 2026 Jan 30. doi: 10.1097/j.pain.0000000000003888.
PubMed

LI Y, Uhelski ML, North RY, Elahi H, et al
Oncostatin M promotes chronic pain through direct regulation on nociceptors in rats.
Pain. 2026 Jan 30. doi: 10.1097/j.pain.0000000000003922.
PubMed Abstract available

ZHANG Y, Wei K, Tao K, Ma M, et al
Mast cell CRFR1 contributes to pancreatic cancer pain via MAPK/SPHK1 signaling.
Pain. 2026 Jan 30. doi: 10.1097/j.pain.0000000000003909.
PubMed Abstract available

RICHTER N, Schmidt S, Pigatto GR, Francis RCE, et al
Dissociating pain dimensions in cold allodynia: subanesthetic ketamine reveals heritable affective-motivational traits in mice.
Pain. 2026 Jan 29. doi: 10.1097/j.pain.0000000000003912.
PubMed Abstract available

CHOWDHURY NS, Bikson M, Gustin SM
A roadmap for transcranial direct current stimulation for chronic pain.
Pain. 2026 Jan 28. doi: 10.1097/j.pain.0000000000003893.
PubMed

MORCHIO M, Sankaranarayanan I, Tavares-Ferreira D, Wong N, et al
Spatially resolved single-cell analysis of transcriptomic changes linked with neuropathic pain in human neuromas.
Pain. 2026 Jan 22. doi: 10.1097/j.pain.0000000000003907.
PubMed Abstract available

HEWITT D, Tong S, Schreiber S, Seymour B, et al
Tonic pain modulates neural correlates of associative phasic pain memories.
Pain. 2026 Jan 21. doi: 10.1097/j.pain.0000000000003917.
PubMed Abstract available

SU W, Antonopoulos CG, Valentini E
Network reorganisation reveals somato-motor transition from segregation to integration during tonic pain.
Pain. 2026 Jan 16. doi: 10.1097/j.pain.0000000000003897.
PubMed Abstract available

BAAL JD, Ghimire P, Wagle S, Lewis M, et al
Identification of peripheral pain generators with sigma-1 receptor Positron Emission Tomography/Magnetic Resonance Imaging in complex regional pain syndrome: initial study in a prospective trial.
Pain. 2026 Jan 15:10.1097/j.pain.0000000000003913.
PubMed Abstract available

FAUCHON C, Corvin S, Faillenot I, Patural H, et al
Parenting and empathy capabilities drive brain response to pain cues in baby cries.
Pain. 2026 Jan 15. doi: 10.1097/j.pain.0000000000003914.
PubMed Abstract available

HASHMI MA, Hashmi JA
Chronic pain and the limits of artificial intelligence: why expert knowledge matters.
Pain. 2026 Jan 14. doi: 10.1097/j.pain.0000000000003891.
PubMed

TODD J, Pickup B, Ji J, Norton A, et al
Momentary assessment of mental imagery and pain-related psychological factors in youth with chronic pain.
Pain. 2026 Jan 14. doi: 10.1097/j.pain.0000000000003902.
PubMed Abstract available

HARTMANN H, Dahmen P, Bingel U, Rutgen M, et al
The effects of different types of pain modulation on social emotions and behaviour-a systematic literature review.
Pain. 2026 Jan 12. doi: 10.1097/j.pain.0000000000003919.
PubMed Abstract available

ELDESOUKY O, Seebauer L, Rukwied R, Carr R, et al
Mismatch between intact electrical excitability and lost heat pain in diabetic neuropathy.
Pain. 2026 Jan 6. doi: 10.1097/j.pain.0000000000003898.
PubMed Abstract available

CUNDIFF-O'SULLIVAN RL, Wang Y, Li J, Latypov TH, et al
Clinical pain increased with older brain age, yet placebo effects were preserved.
Pain. 2026 Jan 6. doi: 10.1097/j.pain.0000000000003901.
PubMed Abstract available

YEH CH, Chen SC
Revisiting pain inhibition in knee osteoarthritis: central dysregulation and the paradox of resilience.
Pain. 2026;167:244-245.
PubMed

December 2025

EDWARDS RR, Tarpey T, Ashburn M, Baer C, et al
A double-blind, placebo-controlled, multi-crossover trial of treatment with a chemokine antagonist for knee osteoarthritis pain.
Pain. 2025 Dec 31. doi: 10.1097/j.pain.0000000000003904.
PubMed Abstract available

TODD J, Sharpe L, Ji J, Pickup B, et al
Reimagining pain: the role of mental imagery in pain experience.
Pain. 2025 Dec 31. doi: 10.1097/j.pain.0000000000003863.
PubMed

STRAUSS S, Lotze M
From trauma to chronic pain: mapping the cellular landscape of painful trigeminal neuromas.
Pain. 2025 Dec 31. doi: 10.1097/j.pain.0000000000003908.
PubMed

MERCHANT G, Ratri A, Wolff SF, Stewart N, et al
Phenotypic characteristics of chronic pain and pain-related factors in gender minority persons: a cross-sectional study.
Pain. 2025 Dec 29. doi: 10.1097/j.pain.0000000000003900.
PubMed Abstract available

WANG S, Eccleston C, Wilmut K, Keefe F, et al
Why can we hurt ourselves? Human agency and embodied action in the attenuation of self-induced pain.
Pain. 2025 Dec 26. doi: 10.1097/j.pain.0000000000003899.
PubMed Abstract available

MILLER CJ, Conroy A, Bilker WB, Stephens-Shields AJ, et al
The impact of opioid withdrawal symptoms on pain outcomes in enriched enrollment randomized withdrawal trials: a mediation meta-analysis of trials submitted to the US Food and Drug Administration.
Pain. 2025 Dec 24. doi: 10.1097/j.pain.0000000000003895.
PubMed Abstract available

ANG D, Kaplan S, Keefe F, Rice W, et al
Duloxetine and cognitive behavioral therapy with phone-based support for the treatment of chronic musculoskeletal pain: a randomized controlled trial.
Pain. 2025 Dec 23. doi: 10.1097/j.pain.0000000000003861.
PubMed Abstract available

EBERHARDT E, Namer B, Neureiter A, Korner J, et al
Spontaneous activity in pain patient stem cell-derived sensory neurons arises from one functional subclass.
Pain. 2025 Dec 19. doi: 10.1097/j.pain.0000000000003865.
PubMed Abstract available

HASHEMI H, Cohen E, Garvey N, Lebovic A, et al
Understanding maternal perspectives of skin-to-skin contact for the management of acute pain in very and extremely preterm infants.
Pain. 2025 Dec 15. doi: 10.1097/j.pain.0000000000003885.
PubMed Abstract available

MATHEVE T, Danneels L, Meulders A, Bogaerts K, et al
Assessing self-reported fear of movement in chronic low back pain: how specific should we be?
Pain. 2025 Dec 10. doi: 10.1097/j.pain.0000000000003894.
PubMed Abstract available

ROBINSON-PAPP J, Rathmell JP, Tarpey T, Troxel AB, et al
When do platform trials in chronic pain make sense?
Pain. 2025 Dec 9. doi: 10.1097/j.pain.0000000000003882.
PubMed

DO J, Kutcher SA, McGregor E, Sucha E, et al
Pain management guidelines reduce opioids in post-operative and mechanically ventilated neonates.
Pain. 2025 Dec 9. doi: 10.1097/j.pain.0000000000003875.
PubMed Abstract available

DEHGHANI A, Gantz DM, Murphy EK, Nitsche MA, et al
Transcranial direct current stimulation of primary motor cortex reduces thermal pain.
Pain. 2025 Dec 4. doi: 10.1097/j.pain.0000000000003851.
PubMed Abstract available

O'DONNELL ML, Arjmand HA, Lumley MA, Seal K, et al
Systematic review and meta-analyses of nonpharmacological interventions for co-occurring chronic pain and posttraumatic stress disorder.
Pain. 2025 Dec 3. doi: 10.1097/j.pain.0000000000003880.
PubMed Abstract available

HARRISON LE, Berger AS, Hess CW, Ma RS, et al
Unequal burden: chronic pain disparities in sexual and gender minority adolescents.
Pain. 2025 Dec 3. doi: 10.1097/j.pain.0000000000003874.
PubMed Abstract available

STAEDTLER ES, Sapio MR, Mannes AJ, Iadarola MJ, et al
Peppers and poppies: a perspective on nociceptors and pain control.
Pain. 2025 Dec 2. doi: 10.1097/j.pain.0000000000003867.
PubMed

PICKUP B, Sharpe L, Menzies RE, Todd J, et al
The pelvic pain bias assessment: a new assessment of interpretation bias specific to pelvic pain.
Pain. 2025 Dec 2. doi: 10.1097/j.pain.0000000000003873.
PubMed Abstract available

JOSEPH M, Sharpe L, Kaiko I, Pickup B, et al
Pain, emotional distress, and fear of recurrence or progression in people with endometriosis: a network approach.
Pain. 2025 Dec 2. doi: 10.1097/j.pain.0000000000003864.
PubMed Abstract available

KARRASCH JF, O'Neil TR, Baharlou H, Dong O, et al
Spatial imaging analysis of cutaneous nerve-myeloid cell interactions in chronic complex regional pain syndrome.
Pain. 2025 Dec 1. doi: 10.1097/j.pain.0000000000003845.
PubMed Abstract available

CHEN SC, Chen CC
Bridging structural gaps in pain research: missed insights from recruitment data on underrepresented populations.
Pain. 2025;166:e864.
PubMed

BOUHASSIRA D
Thermal grill-induced pain: further evidence for its pathophysiological and clinical relevance.
Pain. 2025;166:2683-2684.
PubMed

November 2025

SCHREPF A
Towards symptom-defined patient profiles in chronic pelvic pain: what's in a label?
Pain. 2025 Nov 26. doi: 10.1097/j.pain.0000000000003858.
PubMed

BUDZISZ A, Adamczyk WM, Luedtke K
Perceiving pain alters body perception: the effects of acute pain on body image and sensory testing.
Pain. 2025 Nov 26. doi: 10.1097/j.pain.0000000000003872.
PubMed Abstract available

YUAN R, Cole M, Gewandter J, Markman J, et al
Clinical phenotype matters: structural and functional thalamic changes in neuropathic low-back pain.
Pain. 2025 Nov 25. doi: 10.1097/j.pain.0000000000003843.
PubMed Abstract available

PAYNE LA, Handy AB, Seidman LC, Mitchell CM, et al
Multisensory sensitivity predicts menstrual pain and widespread pain trajectories over 12 months in adolescents with and without primary dysmenorrhea.
Pain. 2025 Nov 24. doi: 10.1097/j.pain.0000000000003868.
PubMed Abstract available

FATEMI SA, Abssy SS, Bourke SL, Murray KB, et al
The contribution of baseline circulating endocannabinoids to individual differences in human pain sensitivity: a quantitative sensory testing study.
Pain. 2025 Nov 24. doi: 10.1097/j.pain.0000000000003850.
PubMed Abstract available

WALTERS ET
Fundamental electrophysiological mechanisms for driving ongoing pain found in human nociceptors.
Pain. 2025 Nov 24. doi: 10.1097/j.pain.0000000000003866.
PubMed

SPILDREJORDE M, Dunker O, Allen SM, Kvaloy MB, et al
Genome-wide association study of neuropathic pain.
Pain. 2025 Nov 21. doi: 10.1097/j.pain.0000000000003848.
PubMed Abstract available

TAN Y, Kashyap Y, De La Toba E, Croslow SW, et al
Hemorphins, atypical endogenous opiate peptides, in sickle cell disease and their association with pain.
Pain. 2025 Nov 19. doi: 10.1097/j.pain.0000000000003859.
PubMed Abstract available

KUHLMANN L, Olesen SS, Dugic A, Phillips AE, et al
Beyond Ammann's pain classification: multidimensional pain phenotyping and cluster analysis in chronic pancreatitis.
Pain. 2025 Nov 13. doi: 10.1097/j.pain.0000000000003839.
PubMed Abstract available

HARRISON LE, Revol J, Lafit G, Ceulemans E, et al
It's all relative: parent pain-related distress and acceptance as predictors of youth outcomes in chronic pain dyads.
Pain. 2025 Nov 13. doi: 10.1097/j.pain.0000000000003846.
PubMed Abstract available

BUTRY L, Angelova M, Belavy DL, Doding R, et al
Lumbar tactile acuity associated with S1-thalamic functional connectivity and S1 microstructure in patients with low back pain and pain-free controls.
Pain. 2025 Nov 13. doi: 10.1097/j.pain.0000000000003841.
PubMed Abstract available

GAMBETA E, Salter MW
Microglia, sex, and pain: even more twists and turns ahead?
Pain. 2025;166.
PubMed Abstract available

SHARMA S, Chala MB, Resende de Jesus-Moraleida F, Than VQ, et al
Tackling the growing burden of pain in low/middle-income countries.
Pain. 2025;166.
PubMed Abstract available

GREEN CR, Villalta FV, Garcia-Almonte EE
Decolonizing pain and health-related research to advance research and optimize health.
Pain. 2025;166.
PubMed Abstract available

CASHIN AG, Sterling M
Optimising physical rehabilitation for people with musculoskeletal pain.
Pain. 2025;166.
PubMed Abstract available

MOHABIR V, Lalloo C, Briggs AM, Eccleston C, et al
The transformative potential of digital therapeutics in pediatrics.
Pain. 2025;166.
PubMed Abstract available

CIAMPI DE ANDRADE D, Shirvalkar P
The future of pain research: neuromodulation and surgery.
Pain. 2025;166.
PubMed Abstract available

MACKEY S, Darnall B, Kao MC
Digital twin learning health systems and multimodal biomarkers transform pain care.
Pain. 2025;166.
PubMed Abstract available

HUTCHINSON MR, Barratt D, Johnston CH, Humphries MA, et al
Biomarkers to predict, prevent, and treat persistent pain: omics.
Pain. 2025;166.
PubMed Abstract available

CRUZ-ALMEIDA Y
Integrated biopsychosocial signatures: moving beyond isolated biomarkers to predict, prevent, and treat persistent pain.
Pain. 2025;166.
PubMed Abstract available

WAGER TD, Sutherland SP, Lindquist MA, Sluka KA, et al
Accelerating discovery in pain science: the Acute to Chronic Pain Signatures program.
Pain. 2025;166.
PubMed Abstract available

BOVA G, De Paepe AL, Nicholson KM, Wandner LD, et al
Moving beyond pain intensity as the primary outcome measure: the INTEGRATE pain framework and beyond.
Pain. 2025;166.
PubMed Abstract available

PETERSEN KK, Hughes S, Vollert J
The use of quantitative sensory testing for personalized pain medicine in the age of AI.
Pain. 2025;166.
PubMed Abstract available

GIERTHMUHLEN J, Bouhassira D
Patient-reported outcomes and quantitative sensory testing: are they useful to investigate neuropathic pain mechanisms and predict therapeutic response?
Pain. 2025;166.
PubMed Abstract available

MAHAJAN P, Seymour B
Forward and reverse engineering the pain system: from computational neuroscience to neuro-engineering.
Pain. 2025;166.
PubMed Abstract available

LOGGIA ML, Brugarolas P, Catana C, Hooker JM, et al
How the next 50 years of positron emission tomography can transform our understanding of chronic pain.
Pain. 2025;166.
PubMed Abstract available

GARCIA-LARREA L, Andre-Obadia N
Electroencephalography, magnetoencephalography and pain: where do we stand, and where are we going.
Pain. 2025;166.
PubMed Abstract available

BORTSOV A, Esfahani SJ, Lima LV, Ji RR, et al
How people resolve pain: insights from human transcriptomics into immune activation and therapeutic innovations.
Pain. 2025;166.
PubMed Abstract available

BANNISTER K, Patel R, Hughes S
The descending modulation of pain.
Pain. 2025;166.
PubMed Abstract available

SLUKA KA, Sowers LP, Fairbanks CA, Lascelles BDX, et al
Moving beyond measures of pain intensity in preclinical models.
Pain. 2025;166.
PubMed Abstract available

FIELDS HL
Lost in translation: past, present, and future of pain research.
Pain. 2025;166.
PubMed Abstract available

DE MORGAN S, Blyth FM, Slater H, Walker P, et al
Leveraging technologies to upskill primary care providers in person-centred pain care.
Pain. 2025;166.
PubMed Abstract available

GHASEMLOU N
Rethinking the temporal dynamics of pain: from 3 months to 3 hours?
Pain. 2025;166.
PubMed Abstract available

BORSOOK D
Allostatic load and pain: instability of a bio-social ecosystem.
Pain. 2025;166.
PubMed Abstract available

GRACE PM, Watkins LR
Reordering neuroimmune signaling to prevent and resolve chronic pain.
Pain. 2025;166.
PubMed Abstract available

RODRIGUEZ-PALMA EJ, Allen HN, Nelson TS, Khanna R, et al
Innovating pain research: bridging gaps and shaping the future.
Pain. 2025;166.
PubMed Abstract available

DAVIS KD
A special supplement to celebrate the 50th anniversary of PAIN: advancing pain research and management for the next 50 years.
Pain. 2025;166.
PubMed

JING H
Advancing understanding of opioid mortality risks beyond initial findings in noncancer pain patients.
Pain. 2025;166:e675-e676.
PubMed

CHEN R, Wei X, Chen C
Potential effect of minocycline for neuroinflammation in chronic low back pain.
Pain. 2025;166:e674-e675.
PubMed

WILSON MV, Davis A, Braithwaite FA, Arnold JB, et al
Co-design of novel resources for pain science education implementation: PainPLaN (Personalised Learning and Navigation to pain education resources).
Pain. 2025;166:e606-e622.
PubMed Abstract available

ROBERSON PNE, Brady KP, Thakur B, Booker S, et al
Family support as a pain protective factor for African American older adults: latent class analyses across 2 national longitudinal data sets.
Pain. 2025;166:2588-2595.
PubMed Abstract available

STUCKY CL
Preclinical spontaneous pain measures may predict clinical analgesic efficacy better than von Frey assays.
Pain. 2025;166:2445-2446.
PubMed

October 2025

ZENG X, Lin J, Liu B, Su Z, et al
Hydrogen-rich water alleviates neuropathic pain through the modulation of bile acid/Takeda G-protein-coupled receptor 5-mediated autophagy.
Pain. 2025 Oct 24. doi: 10.1097/j.pain.0000000000003830.
PubMed Abstract available

DE PAEPE AL, Gibby A, Oporto-Lisboa L, Ehrhardt B, et al
Building causal models in pain research: the case of executive functioning and transitions in pain states.
Pain. 2025 Oct 22. doi: 10.1097/j.pain.0000000000003833.
PubMed Abstract available

PAPIC C, Wyborn J, Schultz R, Kifley A, et al
Prevalence, predictors, and treatment of chronic pain after complicated mild to severe traumatic brain injury: a systematic review and meta-analysis.
Pain. 2025 Oct 21. doi: 10.1097/j.pain.0000000000003831.
PubMed Abstract available

AMORIM AB, Gianola M, Barrows D, Zeidan F, et al
Mindfulness meditation reduces pain more effectively than slow-breathing meditation: the mediating role of respiration.
Pain. 2025 Oct 20. doi: 10.1097/j.pain.0000000000003832.
PubMed Abstract available

AULENKAMP JL, Pawlik RJ, Guddat C, Engler H, et al
Unraveling nocebo effects in visceral pain: negative suggestion and adverse treatment experience uniquely shape visceral pain unpleasantness.
Pain. 2025 Oct 20. doi: 10.1097/j.pain.0000000000003827.
PubMed Abstract available

RANATHUNGA N, Sterling M, Sierra-Silvestre E, Chen J, et al
Small nerve fibre pathology in non-neuropathic chronic pain conditions: a systematic review and meta-analysis.
Pain. 2025 Oct 17. doi: 10.1097/j.pain.0000000000003826.
PubMed Abstract available

BAK AB, Moghaddamjou A, Arnold PM, Harrop JS, et al
Chronic pain after decompression for degenerative cervical myelopathy: a pooled trajectory analysis of individual participant data.
Pain. 2025 Oct 15. doi: 10.1097/j.pain.0000000000003828.
PubMed Abstract available

GLASS J, Long-Mills E, Tumin D, Guillen-Hernandez J, et al
Caregiver-reported chronic pain among children born preterm.
Pain. 2025 Oct 15. doi: 10.1097/j.pain.0000000000003829.
PubMed Abstract available

BROWN MC, Kosinski AS, Fillipo R, Howell G, et al
Patterns and trajectories of peripheral inflammatory cytokines, immune tolerance, and lymphocyte differentiation predict transition from acute to chronic low back pain in a sex- and age-specific manner.
Pain. 2025 Oct 10. doi: 10.1097/j.pain.0000000000003811.
PubMed Abstract available

CERMAK S, Sekerkova G, Martina M, Apkarian AV, et al
The role of corticolimbic perineuronal nets in mice with chronic neuropathic pain.
Pain. 2025 Oct 9. doi: 10.1097/j.pain.0000000000003825.
PubMed Abstract available

LOUIS MH, Legrain V, Aron V, Filbrich L, et al
Complex regional pain syndrome evolution is determined by both biological and psychosocial factors: a 1-year prospective observational study.
Pain. 2025 Oct 8. doi: 10.1097/j.pain.0000000000003815.
PubMed Abstract available

ENDERS JD, Prodoehl EK, Sriram A, Penn SM, et al
Episodic pain in Fabry disease is mediated by a heat shock protein-transient receptor potential cation channel A1 axis.
Pain. 2025 Oct 3. doi: 10.1097/j.pain.0000000000003814.
PubMed Abstract available

VERBRUGGHE J, Meeus M, O'Keeffe M, Hoegh M, et al
Can a suggested physical activity paradox explain pain in workers?
Pain. 2025;166:e487-e488.
PubMed

HASSAN IN
Beyond the bedside: a critical perspective on early prediction of chronic pain after mTBI.
Pain. 2025;166:2440-2441.
PubMed

RICH JJ, Kollas CD
Marijuana may not be an effective substitute for many chronic pain medications: unobserved variable bias in G-method marginal standardization.
Pain. 2025;166:2439-2440.
PubMed

WILLIAMS ACC, Nicholas MK
The psychology of pain: Frank Keefe as Editor-in-Chief of PAIN 2013-2022.
Pain. 2025;166:2205-2212.
PubMed Abstract available

ASSEFA DZ, Xia T, Tefera YG, Jung M, et al
Impacts of opioid stewardship in surgical settings: a scoping review.
Pain. 2025;166:2249-2260.
PubMed Abstract available

SUMMIT AG, Lin HC, Wisner KM, Chen C, et al
Assessing the association between child maltreatment and chronic pain: a cross-sectional co-twin control study.
Pain. 2025 Oct 1. doi: 10.1097/j.pain.0000000000003809.
PubMed Abstract available

September 2025

CIAMPI DE ANDRADE D, Petersen KK
Syndrome-based classifications: the case for paradigm shifts in the assessment of people with pain.
Pain. 2025 Sep 26. doi: 10.1097/j.pain.0000000000003812.
PubMed

GALIMBERTI G, Franchi S, Amodeo G, Romualdi P, et al
The prokineticin system and glia cells as pharmacological targets to control neuroinflammation and to relieve pain in a murine model of Fabry-Anderson disease.
Pain. 2025 Sep 25. doi: 10.1097/j.pain.0000000000003818.
PubMed Abstract available

RENZ MP, Schmidt H, Drusko A, Berhe O, et al
Neural, psychological, and daily life evidence for a transdiagnostic process of affective dysregulation in depression and chronic widespread pain.
Pain. 2025 Sep 19. doi: 10.1097/j.pain.0000000000003800.
PubMed Abstract available

MIRBEYK M, Misra S, Koneru G, Funaro MC, et al
Blood-based protein biomarkers of sickle cell disease pain: a systematic review and meta-analysis.
Pain. 2025 Sep 19. doi: 10.1097/j.pain.0000000000003773.
PubMed Abstract available

SULLIVAN MD, de C Williams AC
Questioning the boundary between pain and suffering.
Pain. 2025 Sep 12. doi: 10.1097/j.pain.0000000000003767.
PubMed Abstract available

MARTIN-HERRERO L, Sunol M, Stewart HJ, Pascual-Diaz S, et al
Brain mechanisms supporting nonpainful multisensory hypersensitivities associated with core disease symptoms in youth with chronic primary pain.
Pain. 2025 Sep 10. doi: 10.1097/j.pain.0000000000003778.
PubMed Abstract available

GIBBY A, Braun M, Bertram W, Crombez G, et al
Changes in problem-solving style when pain does not resolve. A longitudinal analysis of adults with chronic pain after total knee replacement.
Pain. 2025 Sep 9. doi: 10.1097/j.pain.0000000000003799.
PubMed Abstract available

PACKER R, Coley K, Williams AT, Shrine N, et al
Genome-wide association study of neuropathic pain phenotypes implicates loci involved in neural cell adhesion, channels, collagen matrix formation, and immune regulation.
Pain. 2025 Sep 3. doi: 10.1097/j.pain.0000000000003785.
PubMed Abstract available

LI Y, Squillace S, Schafer R, Giancotti LA, et al
Contribution of S1pr1-featured astrocyte subpopulation to cisplatin-induced neuropathic pain in male mice.
Pain. 2025 Sep 3. doi: 10.1097/j.pain.0000000000003780.
PubMed Abstract available

VOLLERT J, Spivack J, Adamson B, Baron R, et al
Real-world data and evidence in pain research: an IMMPACT comprehensive review and best practice recommendations.
Pain. 2025 Sep 3. doi: 10.1097/j.pain.0000000000003798.
PubMed Abstract available

DILDINE TC, Janevic MR, Hood AM, Meints SM, et al
The "External Validity Crisis": now is the time to address the attack on diversity, equity, and inclusion in pain science.
Pain. 2025 Sep 3. doi: 10.1097/j.pain.0000000000003788.
PubMed

VAN DEN BROEKE EN, Deckers L, De Meutter Z, O'Neill F, et al
The effect of acute stress on high-frequency electrical stimulation-induced pain and pinprick hypersensitivity in healthy women.
Pain. 2025 Sep 3. doi: 10.1097/j.pain.0000000000003790.
PubMed Abstract available

SANDSTROM A, Kim M, Weerasekera A, Lin Y, et al
Brain levels of the neurotransmitter gamma-aminobutyric acid are reduced in people with HIV-related neuropathic pain.
Pain. 2025 Sep 3. doi: 10.1097/j.pain.0000000000003794.
PubMed Abstract available

SHEN J, Chen J, Wang Z, Yang L, et al
The role of rostral ventromedial medulla astrocytes in the pathogenesis and modulation of diabetic neuropathic pain.
Pain. 2025 Sep 3. doi: 10.1097/j.pain.0000000000003782.
PubMed Abstract available

August 2025

ROLLET C, Bonnet MP, Viaud M, Lelong N, et al
Frequency and risk factors for acute pain during vaginal birth with epidural analgesia: a nationwide population-based study from the 2021 French National Perinatal Survey.
Pain. 2025 Aug 29. doi: 10.1097/j.pain.0000000000003710.
PubMed Abstract available

REICHMAN O, Sahar T, Ashar YK
Dyspareunia: a novel clinical approach for diagnosis based on pain mechanisms.
Pain. 2025 Aug 27. doi: 10.1097/j.pain.0000000000003807.
PubMed

HOMS AF, Pionnier R, Cohen-Aknine G, Torre K, et al
Task-specific vs general measures of pain-related fear relative associations with spinal motor behaviour: a systematic review and meta-analysis.
Pain. 2025 Aug 27. doi: 10.1097/j.pain.0000000000003797.
PubMed Abstract available

EL-SAYED R, Sanmugananthan VV, Cheng JC, Rogachov A, et al
Individual differences in conditioned pain modulation are associated with alpha oscillations.
Pain. 2025 Aug 27. doi: 10.1097/j.pain.0000000000003804.
PubMed Abstract available

O'CONNELL NE, Abdel-Shaheed C, Qureshi R, Richards GC, et al
To do no harm, we must first "know harms". The challenge of measuring and reporting adverse events in interventions for pain.
Pain. 2025 Aug 26. doi: 10.1097/j.pain.0000000000003796.
PubMed

BRUNEAU A, Sirois A, Spiegler G, Bi J, et al
Factors associated with opioid craving, opioid intake, and opioid misuse in patients with chronic pain: insights from an ecological momentary assessment study.
Pain. 2025 Aug 22. doi: 10.1097/j.pain.0000000000003753.
PubMed Abstract available

GORMSEN L, Fink P, Butler SH, Henningsen P, et al
Can the pain field learn from the functional somatic disorder field?
Pain. 2025 Aug 21. doi: 10.1097/j.pain.0000000000003733.
PubMed

CHANDRA SS, Bisby MA, Scott AJ, Titov N, et al
The endometriosis pain course: a randomized controlled trial of an internet-delivered psychological pain management program for endometriosis.
Pain. 2025 Aug 21. doi: 10.1097/j.pain.0000000000003784.
PubMed Abstract available

ROMAN-JUAN J, Mychasiuk R, Macfarlane GJ, Hood AM, et al
National income inequality and adolescent chronic pain: a time series analysis of 29 countries.
Pain. 2025 Aug 18. doi: 10.1097/j.pain.0000000000003756.
PubMed Abstract available

SHAKERI H, Vueghs C, Benoliel R, May A, et al
Development and validation of the International Classification for Orofacial Pain Algorithm.
Pain. 2025 Aug 13. doi: 10.1097/j.pain.0000000000003783.
PubMed Abstract available

PAMPIRI LM, Hjorthoj C, Kirtley O, Hinze V, et al
Pain and suicidality during adolescence: a Danish National Cohort Study.
Pain. 2025 Aug 13. doi: 10.1097/j.pain.0000000000003769.
PubMed Abstract available

SUN F, Yang Y, Nahin RL
Prevalence and correlates of "undiagnosed pain"-Evidence from the US national Medical Expenditure Panel Survey.
Pain. 2025 Aug 11. doi: 10.1097/j.pain.0000000000003754.
PubMed Abstract available

WEINRICH JAP, Liu CD, Jewell ME, Andolina CR, et al
Paradoxical increases in anterior cingulate cortex activity during nitrous oxide-induced analgesia reveal a signature of pain affect.
Pain. 2025 Aug 11. doi: 10.1097/j.pain.0000000000003771.
PubMed Abstract available

HADJIS GE, Barnett A, Yu A, Lin AY, et al
Salience or value: what drives priority in pain-cognition interactions?
Pain. 2025 Aug 8. doi: 10.1097/j.pain.0000000000003747.
PubMed Abstract available

DALBAGNO D, Betti S, Garofalo S, Mannari V, et al
Learning the time of pain in the human motor system.
Pain. 2025 Aug 6. doi: 10.1097/j.pain.0000000000003730.
PubMed Abstract available

CHEN SP, Lien CC
More is less: enhanced cortical activity and reduced pain under nitrous oxide.
Pain. 2025 Aug 6. doi: 10.1097/j.pain.0000000000003772.
PubMed

ZAJACOVA A, Grol-Prokopczyk H, Nahin RL
Pain among US adults before, during, and after the COVID-19 pandemic: a study using the 2019 to 2023 National Health Interview Survey.
Pain. 2025 Aug 5:10.1097/j.pain.0000000000003764.
PubMed Abstract available

GIANCOTTI LA, Squillace S, Chen Z, Lauro F, et al
Ozanimod, a functional sphingosine-1-phosphate receptor 1 antagonist, restores brainstem descending pain pathways in murine models of neuropathic pain.
Pain. 2025 Aug 4. doi: 10.1097/j.pain.0000000000003770.
PubMed Abstract available

KALINGEL LEVI M, Gal E, Weissman-Fogel I, Bar-Shalita T, et al
Autonomic modulation of pain perception in autism spectrum disorder: unraveling the role of parasympathetic activity among autistic adults.
Pain. 2025 Aug 4. doi: 10.1097/j.pain.0000000000003750.
PubMed Abstract available

SU PP, He L, Zhang L, Yu J, et al
Saphenous-sural nerve injury: a sensory-specific rodent model of neuropathic pain without motor deficits.
Pain. 2025 Aug 4:10.1097/j.pain.0000000000003722.
PubMed Abstract available

RICCIARDI F, Morace AM, Fusco A, Perrone M, et al
Modulatory activity of N-palmitoyl-D-glucosamine in bridging gut dysbiosis and pain mechanisms.
Pain. 2025 Aug 1. doi: 10.1097/j.pain.0000000000003759.
PubMed Abstract available

July 2025

MEYER AR, Garcia G, Mikesell AR, O'Flanagan S, et al
Translational control by general control nonderepressible 2 kinase regulates methylglyoxal-induced pain in mice.
Pain. 2025 Jul 30. doi: 10.1097/j.pain.0000000000003761.
PubMed Abstract available

BREE D, Zhao J, Stratton J, Levy D, et al
Cortical astrocyte activation triggers meningeal nociception and migraine-like pain.
Pain. 2025 Jul 30:10.1097/j.pain.0000000000003737.
PubMed Abstract available

TRAXLER J, Gaggini E, Philips RV, Warny A, et al
Measurement instruments of pain-related avoidance in chronic pain: a systematic review of psychometric properties.
Pain. 2025 Jul 30. doi: 10.1097/j.pain.0000000000003765.
PubMed Abstract available

ZAMORANO AM, Kleber B, De Martino E, Insausti-Delgado A, et al
Prior use-dependent plasticity triggers different individual corticomotor responses during persistent musculoskeletal pain.
Pain. 2025 Jul 30. doi: 10.1097/j.pain.0000000000003749.
PubMed Abstract available

TAYLOR S, Grundy L
Commentary on: A catheter-associated urinary tract infection (CAUTI) mouse model to study bladder dysfunction and pain.
Pain. 2025 Jul 30. doi: 10.1097/j.pain.0000000000003739.
PubMed

BARAKAT A, Doncheva NT, Prado J, Moll L, et al
A ligand-receptor interactome of the bone tumor microenvironment in multiple myeloma bone pain.
Pain. 2025 Jul 29. doi: 10.1097/j.pain.0000000000003746.
PubMed Abstract available

RAWAT A, Vu DT, Erbacher C, Stigloher C, et al
Proteomic analysis of isolated nerve terminals from NaV1.9 knockout mice reveals pathways relevant for pain perception.
Pain. 2025 Jul 29. doi: 10.1097/j.pain.0000000000003743.
PubMed Abstract available

HAMMOND DL
Allan Basbaum: third Editor-in-Chief of PAIN and finding joy in pain research.
Pain. 2025;166:1961-1968.
PubMed Abstract available

ROMAN-JUAN J, Hood AM, Marbil MG, Birnie KA, et al
Borders that hurt: the link between anti-immigration attitudes in Europe and the epidemic of chronic pain in immigrant adolescents.
Pain. 2025 Jul 24. doi: 10.1097/j.pain.0000000000003755.
PubMed Abstract available

ORR JE, Bosompra NO, Norby B, Velazquez J, et al
Chronic pain is associated with sleep apnea severity but attenuated by intermittent hypoxemia in people using opioids.
Pain. 2025 Jul 24. doi: 10.1097/j.pain.0000000000003760.
PubMed Abstract available

HUERTA MA, Roza P, Cisneros E, Alique M, et al
Enhancing clinical translation of analgesics for neuropathic pain: a systematic review and meta-analysis on the role of non-evoked pain assessment in preclinical trials.
Pain. 2025 Jul 24. doi: 10.1097/j.pain.0000000000003697.
PubMed Abstract available

DE C WILLIAMS AC, Azadi A, McGrigor H
Experience of endometriosis pain: a qualitative study.
Pain. 2025 Jul 24. doi: 10.1097/j.pain.0000000000003763.
PubMed Abstract available

HARRISON R, van Reekum CM, Adams G, Gandhi W, et al
Stable individual differences in habituation and sensitization to prolonged painful stimulation are underpinned by activity in the hippocampus, amygdala, and sensorimotor cortices.
Pain. 2025 Jul 24. doi: 10.1097/j.pain.0000000000003636.
PubMed Abstract available

ISLER M, Chu Sin Chung P, Deftu AF, Kirschmann G, et al
A combined activity of peripheral nociceptive and nonnociceptive neurons is necessary to trigger spinal microglial reactivity and sustained pain.
Pain. 2025 Jul 23. doi: 10.1097/j.pain.0000000000003725.
PubMed Abstract available

MORGAN Z, Scott A, Bisby MA, Chandra S, et al
Understanding the untreated course of adults with chronic pain seeking psychological intervention: a systematic review and meta-analysis.
Pain. 2025 Jul 23. doi: 10.1097/j.pain.0000000000003702.
PubMed Abstract available

RODRIGUEZ-PALMA EJ, Khanna R
Ribosomes under stress: GCN2 integrates translational dysfunction and pain signaling.
Pain. 2025 Jul 21:10.1097/j.pain.0000000000003762.
PubMed

SCHILLEBEECKX L, Caldwell A, Luyten K, Sliwinska M, et al
A catheter-associated urinary tract infection mouse model to study bladder dysfunction and pain.
Pain. 2025 Jul 18. doi: 10.1097/j.pain.0000000000003738.
PubMed Abstract available

SAIKA F, Uta D, Fukazawa Y, Hino Y, et al
Androgen receptors expressed in the primary sensory neurons regulate mechanical pain sensitivity.
Pain. 2025 Jul 16. doi: 10.1097/j.pain.0000000000003736.
PubMed Abstract available

BANERJEE G, Brown J, McMichael A, Ben Abdallah A, et al
Androgen levels and experimental pain sensitivity in healthy young adolescent girls.
Pain. 2025 Jul 11:10.1097/j.pain.0000000000003704.
PubMed Abstract available

DAVIS OC, Ferland S, Lorenzo LE, Murray-Lawson C, et al
Decreased KCC2 expression in the human spinal dorsal horn associated with chronic pain and long-term opioid use.
Pain. 2025 Jul 11:10.1097/j.pain.0000000000003700.
PubMed Abstract available

CLARK JD, Kingery WS
Autoantibody-driven pain-Challenges and opportunities.
Pain. 2025 Jul 11. doi: 10.1097/j.pain.0000000000003735.
PubMed

MILIANO C, Chen I, Brown B, Murdaugh LB, et al
12/15-lipoxygenases mediate toll-like receptor 4-dependent nociplastic pain hypersensitivity in female mice.
Pain. 2025 Jul 10:10.1097/j.pain.0000000000003711.
PubMed Abstract available

LIU X, Gao W, Li P, Fan X, et al
Addressing algorithmic bias in AI-based pain management: a comparative analysis of inference models and pretrained large language models.
Pain. 2025;166:2196-2197.
PubMed

COLLIER L, Seah C, Hicks EM, Holtzheimer PE, et al
The impact of chronic pain on brain gene expression.
Pain. 2025 Jul 7:10.1097/j.pain.0000000000003707.
PubMed Abstract available

JIN Y, Aravamudhan A, Cebulla N, Schirmer D, et al
Diminished transient receptor vanilloid 1 on skin nerve fibers in painful bortezomib-induced peripheral neuropathy.
Pain. 2025 Jul 7. doi: 10.1097/j.pain.0000000000003709.
PubMed Abstract available

WEI T, Guo TZ, Shi X, Li WW, et al
Spinal disk injury induces germinal center formation, pronociceptive antibody production, and chronic nociceptive sensitization in a male mouse back pain model.
Pain. 2025 Jul 7:10.1097/j.pain.0000000000003706.
PubMed Abstract available

BEVERIDGE JK, Noel M, McArthur BA, Madigan S, et al
Identifying risk and protective factors in the transmission of chronic pain from mothers to children: a longitudinal cohort study.
Pain. 2025 Jul 7. doi: 10.1097/j.pain.0000000000003698.
PubMed Abstract available

PALERMO TM, Bouhassira D, Davis KD, Hemmings HC Jr, et al
Editorial commitment to trust and integrity in science: implications for pain and anesthesiology research.
Pain. 2025 Jul 3. doi: 10.1097/j.pain.0000000000003681.
PubMed

GOMEZ K, Khanna R
"N-credible" how a tiny viral protein is turning pain into a long-term gig.
Pain. 2025 Jul 3:10.1097/j.pain.0000000000003727.
PubMed

MESAROLI G, Davis AM, Perruccio AV, Davidge KM, et al
Reliability and validity of the Pediatric PainSCAN: a screening tool for pediatric neuropathic pain and complex regional pain syndrome.
Pain. 2025 Jul 2. doi: 10.1097/j.pain.0000000000003682.
PubMed Abstract available

SURI P, Korpak AM, Timmons AK, Tanus AD, et al
Convergent validity of a person-dependent definition of a low back pain flare.
Pain. 2025 Jul 2:10.1097/j.pain.0000000000003703.
PubMed Abstract available

June 2025

GROL-PROKOPCZYK H, Huang R, Yu C, Chen YA, et al
Over 50 years of research on social disparities in pain and pain treatment: a scoping review of reviews.
Pain. 2025 Jun 24. doi: 10.1097/j.pain.0000000000003676.
PubMed Abstract available

ABDELKADER B, Shi XQ, Zhou WBS, Castano JD, et al
Rejuvenation alleviates prolonged postsurgical pain in aging mice by mitigating inflammaging.
Pain. 2025 Jun 24. doi: 10.1097/j.pain.0000000000003684.
PubMed Abstract available

KENNEDY KV, Tupetz A, Boone W, Eucker S, et al
Factors influencing the recruitment of diverse populations into pain research: findings from a qualitative study with underrepresented participants.
Pain. 2025 Jun 20. doi: 10.1097/j.pain.0000000000003641.
PubMed Abstract available

ALTER BJ, Maurer M, O'Connell B, Sanchez AG, et al
Deficits in temporal pain inhibition are associated with greater pain and functional impairment in osteoarthritis.
Pain. 2025 Jun 19. doi: 10.1097/j.pain.0000000000003648.
PubMed Abstract available

MCKIBBEN LA, Woolard A, McLean SA, Zhao Y, et al
Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.
Pain. 2025 Jun 18. doi: 10.1097/j.pain.0000000000003555.
PubMed Abstract available

JONES L, Batalle D, Meek J, Edwards AD, et al
Differential maturation of the brain networks required for the sensory, emotional, and cognitive aspects of pain in human newborns.
Pain. 2025 Jun 18. doi: 10.1097/j.pain.0000000000003619.
PubMed Abstract available

MCKIBBEN LA, Woolard A, McLean SA, Zhao Y, et al
Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.
Pain. 2025;166:2103-2115.
PubMed Abstract available

CLAUW DJ
Quantitative sensory testing in nociplastic pain: what should we be looking for and what does it tell us?
Pain. 2025 Jun 17. doi: 10.1097/j.pain.0000000000003668.
PubMed

WILLIAMS ACC
Commentary: social disparities in pain.
Pain. 2025 Jun 17. doi: 10.1097/j.pain.0000000000003677.
PubMed

ARMFIELD NR, Sterling M
Regarding chronic pain in European adult populations: a systematic review of prevalence and associated clinical features by Rometsch, Caroline et al.
Pain. 2025;166:2194.
PubMed

BILLENS A, De Groote A, Syx D, Meeus M, et al
The influence of genetic and epigenetic variations on dynamic experimental pain measures in adults with and without chronic musculoskeletal pain: a systematic review.
Pain. 2025 Jun 12. doi: 10.1097/j.pain.0000000000003608.
PubMed Abstract available

CLARK JR, Assimakopoulos D, Mailis A
Nociplastic pain criteria must evolve to reduce the problem of "not-classifiable" pain.
Pain. 2025 Jun 11. doi: 10.1097/j.pain.0000000000003667.
PubMed

OSAGIE RO, Tufa I, Angarita-Fonseca A, Page MG, et al
Impact of different acute low back pain definitions on the predictors and on the risk of transition to chronic low back pain: a prospective longitudinal cohort study.
Pain. 2025 Jun 11. doi: 10.1097/j.pain.0000000000003669.
PubMed Abstract available

LIU JK, Zhou ZS, Wang SH, Zuo SY, et al
SARS-CoV-2 N protein interacts with Nav1.7 to promote pathological pain.
Pain. 2025 Jun 4. doi: 10.1097/j.pain.0000000000003675.
PubMed Abstract available

BHATT K, Forget P
Challenges affecting access to pain care in India: why is it different?
Pain. 2025;166:1461-1462.
PubMed

ALCANTARA MONTERO A
Pain in functional gastrointestinal disorders: nociplastic pain or something else?
Pain. 2025;166:1460-1461.
PubMed

WANG C, Ji J, Chen C
From acute injury to chronic pain: key factors and future research directions.
Pain. 2025;166:1459.
PubMed

ZHANG L, Pan L
Long-term impact of physiotherapy attendance on rehabilitation of workers with low back pain.
Pain. 2025;166:1457.
PubMed

May 2025

PESSANO FIALHO MF, Thanigai Arasu GS, Chen S, Imlach WL, et al
Endophilin A1 and synaptojanin 1-dependent endocytosis of synaptic vesicles in nociceptive spinal circuits maintains postoperative and cancer pain.
Pain. 2025 May 27. doi: 10.1097/j.pain.0000000000003657.
PubMed Abstract available

ADAMCZYK WM, Berendt N, Trillenberg P, Hanssen J, et al
Disrupted spatial but not temporal aspects of nociceptive processing determine painful polyneuropathies.
Pain. 2025 May 23. doi: 10.1097/j.pain.0000000000003666.
PubMed Abstract available

LI H, Fan JW, Baldwin E, Luo W, et al
Progression trajectories of chronic overlapping pain conditions unveiled across two large clinical data warehouses.
Pain. 2025 May 23. doi: 10.1097/j.pain.0000000000003650.
PubMed Abstract available

NISHIMURA H, Layne J, Yamaura K, Marcucio R, et al
A bad break: mechanisms and assessment of acute and chronic pain after bone fracture.
Pain. 2025 May 21. doi: 10.1097/j.pain.0000000000003646.
PubMed Abstract available

RUNGE N, Ahmed I, Perea J, Labie C, et al
Terminology and definitions of sleep problems and disorders used in chronic musculoskeletal pain research-a scoping review with recommendations for future research.
Pain. 2025 May 20. doi: 10.1097/j.pain.0000000000003655.
PubMed Abstract available

LI R, Rogers AH, Sujan AC, Zhou C, et al
Psychosocial mechanisms underlying the transition from acute to chronic postsurgical pain in youth following spinal fusion: a 6-month longitudinal study.
Pain. 2025 May 20. doi: 10.1097/j.pain.0000000000003631.
PubMed Abstract available

FINAN PH, Colloca L
Expectations and patient outcomes: a framework for intervention development in chronic pain management.
Pain. 2025 May 19. doi: 10.1097/j.pain.0000000000003654.
PubMed

SIRUCEK L, De Schoenmacker I, Gorrell LM, Lutolf R, et al
The periaqueductal gray in chronic low back pain: dysregulated neurotransmitters and function.
Pain. 2025 May 15. doi: 10.1097/j.pain.0000000000003617.
PubMed Abstract available

DRUMMOND PD, Rossen-Abercromby M, Quartermaine A, Ye D, et al
Spatial distribution of pain in complex regional pain syndrome.
Pain. 2025 May 15. doi: 10.1097/j.pain.0000000000003623.
PubMed Abstract available

SUNAVSKY A, Hashmi MA, Robertson JW, Veinot J, et al
The nucleus accumbens-prefrontal connectivity as a predictor of chronic low back pain.
Pain. 2025 May 15. doi: 10.1097/j.pain.0000000000003620.
PubMed Abstract available

OSTERMANN PN, Madden VJ, Kemp HI, Ciampi de Andrade D, et al
Relevance of chronic pain related to infection for the ICD-11.
Pain. 2025 May 14. doi: 10.1097/j.pain.0000000000003596.
PubMed

TREEDE RD
How to classify patients suffering from chronic pain associated with infectious diseases.
Pain. 2025 May 14. doi: 10.1097/j.pain.0000000000003644.
PubMed

OSTERMANN PN, Madden VJ, Kemp HI, Ciampi de Andrade D, et al
Relevance of chronic pain related to infection for the ICD-11.
Pain. 2025;166:e160-e165.
PubMed Abstract available

LUEPTOW L, Shashkova L, Twombly E, Greenhill H, et al
Chronic pain selectively reduces the motivation to work for remifentanil but not food reward.
Pain. 2025 May 13. doi: 10.1097/j.pain.0000000000003606.
PubMed Abstract available

PETERSON CD, Fairbanks CA
Reduced motivation to seek opioid reward in preclinical studies of pain: a commentary on Lueptow et al.
Pain. 2025 May 13. doi: 10.1097/j.pain.0000000000003607.
PubMed

XU J, Vancleef LMG, Bongaerts E, Van Ryckeghem DML, et al
The association between pain-related cognitive biases and their impact upon task interference by anticipating pain: a virtual reality approach.
Pain. 2025 May 13. doi: 10.1097/j.pain.0000000000003640.
PubMed Abstract available

BRASK-THOMSEN PK, Itani M, Karlsson P, Kristensen AG, et al
Neuropathic pain in diabetic polyneuropathy: a 5-year prospective study.
Pain. 2025 May 13. doi: 10.1097/j.pain.0000000000003649.
PubMed Abstract available

GILRON I, Elkerdawy H, Tu D, Holden RR, et al
Melatonin for neuropathic pain: a double-blind, placebo-controlled, randomized, crossover trial.
Pain. 2025 May 13. doi: 10.1097/j.pain.0000000000003651.
PubMed Abstract available

COHEN M, Quintner J, Weisman A
"Primary" and "nociplastic" pain must not be conflated.
Pain. 2025;166:1949.
PubMed

LUEPTOW L, Shashkova L, Twombly E, Greenhill H, et al
Chronic pain selectively reduces the motivation to work for remifentanil but not food reward.
Pain. 2025;166:e212-e232.
PubMed Abstract available

MILLER CJ, Bilker WB, DeLorey I, Argoff CE, et al
Minimum clinically important differences in acute pain: a patient-level re-analysis of randomized controlled analgesic trials submitted to the US Food and Drug Administration.
Pain. 2025 May 9. doi: 10.1097/j.pain.0000000000003645.
PubMed Abstract available

KAROAM HA, Bruss J, Champoux K, Lemos MD, et al
Neuroanatomy and lesion networks of central poststroke pain.
Pain. 2025 May 9. doi: 10.1097/j.pain.0000000000003618.
PubMed Abstract available

GERA O, Ginzburg K, Gur N, Defrin R, et al
Effects of acute stress exposure on pain sensitivity: the role of individual stress responsiveness and orientation to pain and stress.
Pain. 2025 May 9. doi: 10.1097/j.pain.0000000000003622.
PubMed Abstract available

SPARBER P, Zernov N, Markova T, Sharkova I, et al
Clinical features and functional analysis of novel SCN9A variants causing congenital insensitivity to pain.
Pain. 2025 May 9. doi: 10.1097/j.pain.0000000000003628.
PubMed Abstract available

KAROAM HA, Bruss J, Champoux K, Lemos MD, et al
Neuroanatomy and lesion networks of central poststroke pain.
Pain. 2025;166:e303-e313.
PubMed Abstract available

STEMPER B, Lowen S, Fritsch A, Hoffmann A, et al
The bradykinin-1 receptor antagonist fulmetibant in patients with diabetic neuropathic pain: the randomized, crossover, placebo-controlled, double-blind, phase 2a BRADiNP study.
Pain. 2025 May 6. doi: 10.1097/j.pain.0000000000003642.
PubMed Abstract available

TAKAOKA S, Saito H, Kawate M, Tanaka C, et al
Exploring the presence of long COVID-like symptoms in patients with chronic pain: a large-scale internet-based cross-sectional study in Japan.
Pain. 2025 May 6. doi: 10.1097/j.pain.0000000000003643.
PubMed Abstract available

JONES SA, Bango CI, Shao S, Del Rubin DY, et al
White matter microstructural associations with pain experiences in a large community sample of youth.
Pain. 2025 May 2. doi: 10.1097/j.pain.0000000000003580.
PubMed Abstract available

DILDINE TC
Is a career in science still viable for emerging scholars in pain and health equity?
Pain. 2025;166:1214.
PubMed

ZHANG J, Jiao H
Enhancing precision in pain management for inflammatory arthritis: exploring the potential role of lidocaine in pain mechanism differentiation.
Pain. 2025;166:1213.
PubMed

YANG X
Advancing menopausal pain management: the necessity of multidimensional analysis and interdisciplinary collaboration.
Pain. 2025;166:1212.
PubMed

LIU S, Crawford J, Maltezos H, Sun Y, et al
A glutamatergic brain neural circuit is critical for modulating trigeminal neuropathic pain.
Pain. 2025 May 1. doi: 10.1097/j.pain.0000000000003647.
PubMed Abstract available

April 2025

PHAM TL, Sharma R, Neupane C, Gao F, et al
Neuronal STING-GAT1 signaling maintains paclitaxel-induced neuropathic pain in the spinal cord.
Pain. 2025 Apr 29. doi: 10.1097/j.pain.0000000000003593.
PubMed Abstract available

ZHENG XX, Wang F, Ding H, Li HT, et al
cGMP-dependent protein kinase I in the dorsal hippocampus protects against synaptic plasticity and cognitive deficit induced by chronic pain.
Pain. 2025 Apr 29. doi: 10.1097/j.pain.0000000000003624.
PubMed Abstract available

OSBORNE NR, Hellman KM, Burda EM, Darnell SE, et al
Multimodal hypersensitivity and somatic symptoms predict adolescent postmenarchal widespread pain.
Pain. 2025 Apr 29. doi: 10.1097/j.pain.0000000000003597.
PubMed Abstract available

DREWES AM
Unraveling the puzzle of pain in pancreatic diseases.
Pain. 2025 Apr 29. doi: 10.1097/j.pain.0000000000003603.
PubMed

GEHA P, Sulovari A, Freeman R, Gewandter JS, et al
Dopaminergic modulation: revisiting a promising novel pathway for pharmacologic treatment of chronic pain.
Pain. 2025 Apr 25. doi: 10.1097/j.pain.0000000000003598.
PubMed

JIANG YP, Wen JJ, Ma X, Yuan CR, et al
CRMP2 phosphorylation regulates polarization and spinal infiltration of CD4+ T lymphocytes, inhibits spinal glial activation, and arthritic pain.
Pain. 2025 Apr 22. doi: 10.1097/j.pain.0000000000003599.
PubMed Abstract available

TODD J, Pickup B, Coutts-Bain D, Duijzings M, et al
Interpretation bias and its relationship with pain: a systematic review and meta-analysis.
Pain. 2025 Apr 17. doi: 10.1097/j.pain.0000000000003612.
PubMed Abstract available

KARRAN EL, Cashin AG, Barker T, Boyd MA, et al
Developing consensus on the most important equity-relevant items to include in pain research: a modified e-Delphi study.
Pain. 2025 Apr 16. doi: 10.1097/j.pain.0000000000003621.
PubMed Abstract available

VAN RYCKEGHEM DML, Mac Goris J
Beyond the ambiguity of interpretation bias for pain-related information.
Pain. 2025 Apr 16. doi: 10.1097/j.pain.0000000000003613.
PubMed

CRAWFORD LS, Yang S, Meylakh N, Sattarov L, et al
Forebrain networks driving brainstem pain modulatory circuits during nocebo hyperalgesia in healthy humans.
Pain. 2025 Apr 15. doi: 10.1097/j.pain.0000000000003604.
PubMed Abstract available

ZENG J, Zhou Z
Expanding the smoking-chronic musculoskeletal pain nexus: beyond toxicants to behavioral and psychological factors.
Pain. 2025;166:1707-1708.
PubMed

MOHAMMADIAN M, Morrissey EJ, Knight PC, Brusaferri L, et al
Investigating the potential of minocycline in reducing brain inflammation in chronic low back pain: a randomized, placebo-controlled mechanistic clinical trial.
Pain. 2025 Apr 9. doi: 10.1097/j.pain.0000000000003543.
PubMed Abstract available

GOLTL P, Merz P, Schneider A, Ebert MP, et al
Somatosensory profiling to differentiate distinct painful diseases of the pancreas-a quantitative sensory testing case-control study.
Pain. 2025 Apr 4. doi: 10.1097/j.pain.0000000000003601.
PubMed Abstract available

DE LA PENA JB, Garcia G, Campbell ZT
Ribosome profiling reveals that post-transcriptional control of Nalf1 by heterogeneous nuclear ribonucleoprotein L is required for paclitaxel-induced neuropathic pain.
Pain. 2025 Apr 2. doi: 10.1097/j.pain.0000000000003577.
PubMed Abstract available

DAGENAIS P, Courteau M, Courteau J, Martel G, et al
Care trajectories for musculoskeletal disorders following a new episode of low back pain.
Pain. 2025;166:835-846.
PubMed Abstract available

KEY B, Brown D
Thoughts explain but do not cause pain.
Pain. 2025;166:960.
PubMed

ANDRASSY B, Mukhdomi J
Contextualizing skin changes in acute complex regional pain syndrome.
Pain. 2025;166:956.
PubMed

ROMETSCH C, Martin A, Junne F, Cosci F, et al
Chronic pain in European adult populations: a systematic review of prevalence and associated clinical features.
Pain. 2025;166:719-731.
PubMed Abstract available

CHEN J, Farrell SF, Huang WI, Cagnie B, et al
Differences in the clinical presentation of chronic whiplash-associated disorders and nontraumatic neck pain: a systematic review and meta-analysis.
Pain. 2025 Apr 1. doi: 10.1097/j.pain.0000000000003554.
PubMed Abstract available

SU IW, Hung CH, Lin JH, Chen CC, et al
A revisit of soreness and acidosis-related pain.
Pain. 2025 Apr 1. doi: 10.1097/j.pain.0000000000003595.
PubMed

March 2025

MUN CJ, Tsang S, Reid MJ, Tennen H, et al
Effects of sleep and circadian rest-activity rhythms on daily pain severity in women with temporomandibular disorders.
Pain. 2025 Mar 28. doi: 10.1097/j.pain.0000000000003578.
PubMed Abstract available

BADZINSKA J, Zeglen M, Kryst L, Babel P, et al
What you don't know can hurt others. A systematic review on calibration of stimulus intensity in pain research.
Pain. 2025 Mar 27. doi: 10.1097/j.pain.0000000000003588.
PubMed Abstract available

STERLING M, Hodges P
Pain Commentary on Spinal hyperexcitability in patients with chronic musculoskeletal pain or headache as evidenced by alterations in the nociceptive withdrawal reflex: a systematic review and meta-analysis.
Pain. 2025 Mar 25. doi: 10.1097/j.pain.0000000000003567.
PubMed

CHANG JR, Kwan RLC, Sun ER, Li SX, et al
Differential pain perception among females with or without nonspecific chronic low back pain and comorbid insomnia: a quantitative sensory testing analysis.
Pain. 2025 Mar 20. doi: 10.1097/j.pain.0000000000003591.
PubMed Abstract available

RYU J, Kao JC, Bari A
Spontaneous pain dynamics characterized by stochasticity in neural recordings of awake humans with chronic pain.
Pain. 2025 Mar 20. doi: 10.1097/j.pain.0000000000003592.
PubMed Abstract available

SIMONS LE
Validation of ICD-11 chronic pain severity specifiers for children and adolescents: an important step forward.
Pain. 2025 Mar 20. doi: 10.1097/j.pain.0000000000003585.
PubMed

RYU J, Kao JC, Bari A
Spontaneous pain dynamics characterized by stochasticity in neural recordings of awake humans with chronic pain.
Pain. 2025;166:e261-e275.
PubMed Abstract available

SIMONS LE
Validation of ICD-11 chronic pain severity specifiers for children and adolescents: an important step forward.
Pain. 2025;166:1957-1958.
PubMed

VLAEYEN JWS, Milde C
The precarious use of group data to understand individual processes in pain science.
Pain. 2025 Mar 19. doi: 10.1097/j.pain.0000000000003574.
PubMed

RAU LM, Korwisi B, Barke A, Claus BB, et al
International Classification of Diseases-11 chronic pain severity specifiers for children and adolescents: a validation study.
Pain. 2025 Mar 18. doi: 10.1097/j.pain.0000000000003584.
PubMed Abstract available

SUNDSTROM FTA, Lavefjord A, Buhrman M, McCracken LM, et al
Are people with chronic pain more diverse than we think? An investigation of ergodicity.
Pain. 2025 Mar 18. doi: 10.1097/j.pain.0000000000003573.
PubMed Abstract available

NASTAJ J, Skalski J, Nowak D, Kruszyna N, et al
Pain distribution can be determined by classical conditioning.
Pain. 2025 Mar 18. doi: 10.1097/j.pain.0000000000003586.
PubMed Abstract available

ALAYOUBI M, Rodrigues A, Wu C, Whitehouse E, et al
Elucidating interplay between myrcene and cannabinoid receptor 1 receptors to produce antinociception in mouse models of neuropathic pain.
Pain. 2025 Mar 18. doi: 10.1097/j.pain.0000000000003558.
PubMed Abstract available

WEI YJ, Schmidt S, Fillingim RB, Brock G, et al
Unrelieved pain and risk of opioid use disorder or overdose in older adults prescribed opioids.
Pain. 2025 Mar 18. doi: 10.1097/j.pain.0000000000003589.
PubMed Abstract available

MASCIO G, Notartomaso S, Ginerete RP, Imbriglio T, et al
Formation of perineuronal nets within a thalamocortical circuit shapes mechanical and thermal pain thresholds in mice with neuropathic pain.
Pain. 2025 Mar 17. doi: 10.1097/j.pain.0000000000003563.
PubMed Abstract available

LIBERATI G
Neural biomarkers of pain: defining perspectives and limitations of peak alpha frequency.
Pain. 2025 Mar 14. doi: 10.1097/j.pain.0000000000003572.
PubMed

PALERMO TM, Srinakarin K, Zhou C, Lalloo C, et al
Moderators of digital cognitive-behavioral therapy for youth with sickle cell disease pain: secondary analysis of a randomized controlled trial.
Pain. 2025 Mar 13. doi: 10.1097/j.pain.0000000000003583.
PubMed Abstract available

GOLDFARB C, King CD
Exploring the interactions between circadian rhythms and sleep on pain: a call to action.
Pain. 2025 Mar 13. doi: 10.1097/j.pain.0000000000003579.
PubMed

ATTIAS S, Ramon-Gonen R, Erez Y, Bosak N, et al
Deep learning modelling of structural brain MRI in chronic head and neck pain after mild TBI.
Pain. 2025 Mar 12. doi: 10.1097/j.pain.0000000000003587.
PubMed Abstract available

MAY ES, Tiemann L, Gil Avila C, Bott FS, et al
Assessing the predictive value of peak alpha frequency for the sensitivity to pain.
Pain. 2025 Mar 11. doi: 10.1097/j.pain.0000000000003571.
PubMed Abstract available

DORFMAN CS, Heapy AA, de C Williams AC, Keefe FJ, et al
Maintenance of treatment gains from psychological treatments for chronic pain: what (little) we know, and the urgent need to extend it.
Pain. 2025 Mar 11. doi: 10.1097/j.pain.0000000000003552.
PubMed

LI H, Han L, Li P, Lu D, et al
Pain sensation and emotion induced by aromatase inhibitors: a new mouse model.
Pain. 2025 Mar 5. doi: 10.1097/j.pain.0000000000003505.
PubMed Abstract available

DE SOUZA S, Laumet S, Hua H, Inyang KE, et al
Mast cell-derived chymases are essential for the resolution of inflammatory pain in mice.
Pain. 2025 Mar 4. doi: 10.1097/j.pain.0000000000003565.
PubMed Abstract available

SHAFIR R, Watson L, Felix RB, Muhammed S, et al
Factors influencing the hypoalgesic effects of virtual reality.
Pain. 2025;166:1836-1846.
PubMed Abstract available

YANG J, Xie YF, Smith R, Ratte S, et al
Discordance between preclinical and clinical testing of Na V 1.7-selective inhibitors for pain.
Pain. 2025;166:481-501.
PubMed Abstract available

HUANG F, Chen R
Relationship between the age at menopause and chronic pain in postmenopausal women.
Pain. 2025;166:710.
PubMed

SHEN CY, Li CP, Gau SY, Chang HC, et al
Real-world evidence regarding the causal effect of pain on mortality.
Pain. 2025;166:708.
PubMed

February 2025

BERGERIA CL, Mun CJ, Speed TJ, Huhn AS, et al
A within-subject, double-blind, placebo-controlled randomized evaluation of the combined effects of cannabidiol and hydromorphone in a human laboratory pain model.
Pain. 2025 Feb 28. doi: 10.1097/j.pain.0000000000003561.
PubMed Abstract available

TAYLOR J, Travaglini L, O'Connell M, Carreno PK, et al
Inequities time-to-follow-up care and administrative action after low back pain diagnosis in active duty service members.
Pain. 2025 Feb 28. doi: 10.1097/j.pain.0000000000003559.
PubMed Abstract available

EVANS DW, Liew BXW, Andersen JH, Mose S, et al
Where is the pain? Spatial patterns of pain co-occurrence in a population-based study of 4833 pain drawings incorporating network analysis.
Pain. 2025 Feb 25. doi: 10.1097/j.pain.0000000000003551.
PubMed Abstract available

SESSLE BJ
Ronald Dubner: pioneer in pain research, founding member of the International Association for the Study of Pain, and Former Editor-in-Chief of PAIN.
Pain. 2025 Feb 25. doi: 10.1097/j.pain.0000000000003548.
PubMed Abstract available

NEUGEBAUER V, Antenucci N
Perineuronal nets in the brain: new vistas in pain mechanisms.
Pain. 2025 Feb 25. doi: 10.1097/j.pain.0000000000003564.
PubMed

KAPPESSER J, Williams ACC
Give and take: an evolutionary framework for social transactions in pain.
Pain. 2025 Feb 21. doi: 10.1097/j.pain.0000000000003520.
PubMed

BIRKINSHAW H, de C Williams AC, Friedrich C, Lee C, et al
Interpersonal dyadic influences on transitions between pain states: a narrative review and synthesis.
Pain. 2025 Feb 21. doi: 10.1097/j.pain.0000000000003544.
PubMed Abstract available

GALOSI E, Falco P, Di Pietro G, Esposito N, et al
Epidermal Transient Receptor Potential Vanilloid 1 innervation is increased in patients with painful diabetic polyneuropathy experiencing ongoing burning pain.
Pain. 2025 Feb 19. doi: 10.1097/j.pain.0000000000003541.
PubMed Abstract available

DAVIS KD
The value of equity, diversity, and inclusion principles and sex/gender considerations in pain research.
Pain. 2025 Feb 19. doi: 10.1097/j.pain.0000000000003569.
PubMed

LIN CJ, Hsueh HW, Chiang MC, Hsieh ST, et al
Cortical reorganization in neuropathic pain due to peripheral nerve degeneration: altered cortical surface morphometry and hierarchical topography.
Pain. 2025 Feb 18. doi: 10.1097/j.pain.0000000000003557.
PubMed Abstract available

SHI Y, Wu W
Advancements and prospects of transcranial focused ultrasound in pain neuromodulation.
Pain. 2025 Feb 18. doi: 10.1097/j.pain.0000000000003556.
PubMed Abstract available

BAUMBACH P, Zaslansky R, Dreiling J, Komann M, et al
Early opioid administration and pain-related patient-reported outcomes on the first postoperative day: an analysis of data from 111,693 patients in 392 surgical wards in Germany.
Pain. 2025 Feb 18. doi: 10.1097/j.pain.0000000000003545.
PubMed Abstract available

FINAN PH
Set and setting in mind-body interventions for pain: lessons from an experimental evaluation of virtual reality.
Pain. 2025 Feb 18. doi: 10.1097/j.pain.0000000000003550.
PubMed

RODRIGUEZ-PALMA EJ, Khanna R
Mast cell chymases: essential for preventing the transition from acute to chronic pain.
Pain. 2025 Feb 18. doi: 10.1097/j.pain.0000000000003566.
PubMed

PREMACHANDRAN S, Ocay DD, Beaulieu C, Balduzzi J, et al
Pain experience of children with Christianson syndrome.
Pain. 2025 Feb 6. doi: 10.1097/j.pain.0000000000003522.
PubMed Abstract available

GARFINKEL SN, Eccleston C
Interoception and pain: body-mind integration, rupture, and repair.
Pain. 2025 Feb 6. doi: 10.1097/j.pain.0000000000003515.
PubMed

KAPITZA C, Ballenberger N, Luedtke K, Schmid AB, et al
Somatosensory and clinical profiles of patients with spine-related and clinical framework-based neck-arm pain.
Pain. 2025 Feb 5. doi: 10.1097/j.pain.0000000000003516.
PubMed Abstract available

GAULTNEY W, Jimenez N, Correa-Medina A, Campbell CM, et al
Social determinants of health in pediatric chronic postsurgical pain research.
Pain. 2025 Feb 5. doi: 10.1097/j.pain.0000000000003510.
PubMed

LAUTENBACHER S, Horn-Hofmann C, Kunz M
Conditioned pain modulation: controlling for the order of baseline and conditioning.
Pain. 2025 Feb 4. doi: 10.1097/j.pain.0000000000003494.
PubMed Abstract available

JIANG W, Yu P, Yang Y, Cai MT, et al
PI3K-mediated Kif1a DNA methylation contributes to neuropathic pain: an in vivo study.
Pain. 2025 Feb 4. doi: 10.1097/j.pain.0000000000003536.
PubMed Abstract available

DJADE CD, Diorio C, Laurin D, Talbot D, et al
An examination of acrylamide and cadmium as possible mediators of the association between cigarette smoking and chronic musculoskeletal pain.
Pain. 2025 Feb 3. doi: 10.1097/j.pain.0000000000003517.
PubMed Abstract available

SUN Q, Weng RX, Li YC, Jia SM, et al
Potentiation of visualized exosomal miR-1306-3p from primary sensory neurons contributes to chronic visceral pain via spinal P2X3 receptors.
Pain. 2025 Feb 3. doi: 10.1097/j.pain.0000000000003537.
PubMed Abstract available

BAUTIN P, Fortier MA, Sean M, Little G, et al
What has brain diffusion magnetic resonance imaging taught us about chronic primary pain: a narrative review.
Pain. 2025;166:243-261.
PubMed Abstract available

Astrocytic phosphatase and tensin homolog deleted on chromosome 10 regulates neuropathic pain by facilitating 3-hydroxy-3-methylglutaryl-CoA reductase-dependent cholesterol biosynthesis: Erratum.
Pain. 2025;166:467.
PubMed

Noninvasive targeted modulation of pain circuits with focused ultrasonic waves: Erratum.
Pain. 2025;166:466.
PubMed

SUN L, Feng Y
Chronic postsurgical pain in pediatric patients: perioperative risk factors and preventive actions.
Pain. 2025;166:461-462.
PubMed

January 2025

BALLANTYNE JC
Another piece in the marijuana for pain quandary.
Pain. 2025 Jan 28. doi: 10.1097/j.pain.0000000000003507.
PubMed

WILSON MV, Braithwaite FA, Arnold JB, Stanton TR, et al
Real-world implementation of pain science education and barriers to use in private practice physiotherapy settings: an Australia-wide cross-sectional survey.
Pain. 2025 Jan 28. doi: 10.1097/j.pain.0000000000003521.
PubMed Abstract available

YI W, Palmer C, Serian A, Roy M, et al
Individualizing musical tempo to spontaneous rates maximizes music-induced hypoalgesia.
Pain. 2025;166:1761-1768.
PubMed Abstract available

WASAN AD, O'Connell B, DeSensi R, Bernstein C, et al
The comparative effectiveness of medicinal cannabis for chronic pain versus prescription medication treatment.
Pain. 2025 Jan 24. doi: 10.1097/j.pain.0000000000003506.
PubMed Abstract available

SOUSA SHIMAMURA LK, Bettiol H, Moura da Silva AA, Nogueira AA, et al
Incidence of chronic pelvic pain after childbirth and its causal association with C-section.
Pain. 2025 Jan 22. doi: 10.1097/j.pain.0000000000003519.
PubMed Abstract available

GRANT AR, Westhorp G, Murray CM, de la Perrelle L, et al
Increasing access to pain care services to improve rural pain management: a realist review investigating factors affecting uptake, implementation, and sustainability.
Pain. 2025 Jan 21. doi: 10.1097/j.pain.0000000000003482.
PubMed Abstract available

HUBSCHMID F, Flury ML, Loffler M, Desch S, et al
Mechanisms of increased pain discrimination by contingent reinforcement: a perceptual decision-making and instrumental learning account.
Pain. 2025 Jan 21. doi: 10.1097/j.pain.0000000000003514.
PubMed Abstract available

GRAHAM H, Razaz N, Hakansson S, Blomqvist YT, et al
Pain in very preterm infants-prevalence, causes, assessment, and treatment. A nationwide cohort study.
Pain. 2025 Jan 21. doi: 10.1097/j.pain.0000000000003528.
PubMed Abstract available

SLATER H, Waller R, Briggs AM, Lord SM, et al
Characterizing phenotypes and clinical and health utilization associations of young people with chronic pain: latent class analysis using the electronic Persistent Pain Outcomes Collaboration database.
Pain. 2025;166:67-86.
PubMed Abstract available

DUFFEE C
Conceptual and historical blind spots of large language models in research on pain-related suffering.
Pain. 2025;166:222.
PubMed

DEVOR M
Experiencing pain: perspectives of Patrick D. Wall-founding editor of the journal PAIN.
Pain. 2025;166:11-19.
PubMed Abstract available

DAVIS KD, Ballantyne JC
The 50th anniversary of PAIN: a celebration and introducing Pain Essays.
Pain. 2025;166:1-2.
PubMed

December 2024

BARON M, Vaso K, Ibraheem A, Minert A, et al
Molecular and cellular targets of GABAergic anesthetics in the mesopontine tegmentum that enable pain-free surgery.
Pain. 2024 Dec 31. doi: 10.1097/j.pain.0000000000003504.
PubMed Abstract available

RESCH FJ, Heber S, Shahi F, Zauner M, et al
Human cold pain: a randomized crossover trial.
Pain. 2024 Dec 17. doi: 10.1097/j.pain.0000000000003503.
PubMed Abstract available

LATYPOV TH, Wolfensohn A, Yakubov R, Li J, et al
Signatures of chronic pain in multiple sclerosis: a machine learning approach to investigate trigeminal neuralgia.
Pain. 2024 Dec 13. doi: 10.1097/j.pain.0000000000003497.
PubMed Abstract available

MELLADO LAGARDE MM, Wilbraham D, Martins RF, Zhao HS, et al
Clinical proof-of-concept results with a novel TRPA1 antagonist (LY3526318) in 3 chronic pain states.
Pain. 2024 Dec 13. doi: 10.1097/j.pain.0000000000003487.
PubMed Abstract available

HARRISON LE, Boerner KE, Black W, Nelson S, et al
A call to action to integrate best practice assessment of sexual orientation and gender identity in pain research and clinical care.
Pain. 2024 Dec 13. doi: 10.1097/j.pain.0000000000003481.
PubMed

LIBERATI G
Advancements in noninvasive brain stimulation: exploring repetitive transcranial magnetic stimulation of the posterior superior insula for pain relief.
Pain. 2024 Dec 12. doi: 10.1097/j.pain.0000000000003489.
PubMed

CHOWDHURY NS, Millard SK, de Martino E, Larsen DB, et al
Posterior-superior insula repetitive transcranial magnetic stimulation reduces experimental tonic pain and pain-related cortical inhibition in humans.
Pain. 2024 Dec 11. doi: 10.1097/j.pain.0000000000003488.
PubMed Abstract available

CARDOSO-CRUZ H, Monteiro C, Galhardo V
Reorganization of lateral habenula neuronal connectivity underlies pain-related impairment in spatial memory encoding.
Pain. 2024 Dec 11. doi: 10.1097/j.pain.0000000000003493.
PubMed Abstract available

CAMERONE EM, Tosi G, Romano D
The role of pain expectancy and its confidence in placebo hypoalgesia and nocebo hyperalgesia.
Pain. 2024 Dec 10. doi: 10.1097/j.pain.0000000000003495.
PubMed Abstract available

STEVENS B, Bueno M, Barwick M, Campbell-Yeo M, et al
The implementation of infant pain practice change resource to improve infant procedural pain practices: a hybrid type 1 effectiveness-implementation study.
Pain. 2024 Dec 6. doi: 10.1097/j.pain.0000000000003496.
PubMed Abstract available

NAEINI MK, Cecelja M, Freidin MB, Smith IG, et al
Chronic widespread musculoskeletal pain shares a highly heritable latent pathway with atherosclerosis and arterial stiffness.
Pain. 2024 Dec 3. doi: 10.1097/j.pain.0000000000003486.
PubMed Abstract available

CHOWDHURY NS, Taseen KJ, Chiang AK, Chang WJ, et al
A 5-day course of repetitive transcranial magnetic stimulation before pain onset ameliorates future pain and increases sensorimotor peak alpha frequency.
Pain. 2024 Dec 3. doi: 10.1097/j.pain.0000000000003484.
PubMed Abstract available

ADAMCZYK WM, Ramu V, Jackson C, Schulze G, et al
Radiation of pain: psychophysical evidence for a population coding mechanism in humans.
Pain. 2024 Dec 2. doi: 10.1097/j.pain.0000000000003474.
PubMed Abstract available

PEYRON R, Raffin E
Dimming chronic pain with ultrasound: hope for the future?
Pain. 2024;165:2660-2661.
PubMed

STURGEON JA, Ziadni M, Trost Z, Hassett AL, et al
Scratching the surface: the complex interface of chronic pain and mental health treatment needs in the United States.
Pain. 2024;165:2657-2659.
PubMed

KAYA B, Boerner KE, Lord RC, Potter E, et al
Body image, sex, gender, and pain: towards an improved understanding of pain mechanisms.
Pain. 2024;165:2673-2678.
PubMed

November 2024

SANDY-HINDMARCH OP, Chang PS, Scheuren PS, De Schoenmacker I, et al
The local molecular signature of human peripheral neuropathic pain.
Pain. 2024 Nov 25. doi: 10.1097/j.pain.0000000000003472.
PubMed Abstract available

KUTCH JJ
Preparing the brain for pain: new insights and potential biomarkers.
Pain. 2024 Nov 21. doi: 10.1097/j.pain.0000000000003485.
PubMed

LI JZ, Mills EP, Osborne NR, Cheng JC, et al
Individual differences in conditioned pain modulation are associated with functional connectivity within the descending antinociceptive pathway.
Pain. 2024 Nov 19. doi: 10.1097/j.pain.0000000000003478.
PubMed Abstract available

GNALL KE, Jochimsen KN, Brewer JR, Bakhshaie J, et al
Pain catastrophizing and pain anxiety mediate changes in physical function in a mind-body intervention for adults with traumatic orthopedic injuries.
Pain. 2024 Nov 19. doi: 10.1097/j.pain.0000000000003477.
PubMed Abstract available

DI DONATO M
A realist review of rural pain management: comprehensive and practical.
Pain. 2024 Nov 19. doi: 10.1097/j.pain.0000000000003483.
PubMed

MUNNEKE W, De Kooning M, Nijs J, Morin C, et al
Enhancing healthcare professionals' biopsychosocial perspective to chronic pain: assessing the impact of implementing an interdisciplinary training program.
Pain. 2024 Nov 12. doi: 10.1097/j.pain.0000000000003403.
PubMed Abstract available

EDWARDS KA, Merlin JS, Webster F, Mackey SC, et al
Breaking barriers: addressing opioid stigma in chronic pain and opioid use disorder.
Pain. 2024 Nov 12. doi: 10.1097/j.pain.0000000000003475.
PubMed

O'BRIEN JA, Price TJ
Gaining a new footing on molecular mechanisms of neuropathic pain in patients.
Pain. 2024 Nov 12. doi: 10.1097/j.pain.0000000000003473.
PubMed

REDDY P, Narayan Prajapati J, Chaterji S, Varughese A, et al
Converging inputs compete at the lateral parabrachial nuclei to dictate the affective-motivational responses to cold pain.
Pain. 2024 Nov 12. doi: 10.1097/j.pain.0000000000003468.
PubMed Abstract available

MARTIN MK, Rodriguez R, Guerrero G, Sheehan GD, et al
Pharmacologically enabling the degradation of NaV1.8 channels to reduce neuropathic pain.
Pain. 2024 Nov 8. doi: 10.1097/j.pain.0000000000003470.
PubMed Abstract available

FLYNN DM, Ransom JC, Steffen AD, Orr KP, et al
Complementary, integrative, and standard rehabilitative therapies in a military population with chronic predominantly musculoskeletal pain: a pragmatic clinical trial with SMART design.
Pain. 2024 Nov 8. doi: 10.1097/j.pain.0000000000003462.
PubMed Abstract available

RHUDY JL, Kell PA, Brown TV, Ventresca HM, et al
Mechanisms of the Native American pain inequity: predicting chronic pain onset prospectively at 5 years in the Oklahoma Study of Native American Pain Risk.
Pain. 2024 Nov 7. doi: 10.1097/j.pain.0000000000003442.
PubMed Abstract available

FARRAR JT, Locke KT Jr, Clemens JQ, Griffith JW, et al
Widespread pain phenotypes impact treatment efficacy results in randomized clinical trials for interstitial cystitis/bladder pain syndrome: a Multidisciplinary Approach to the Study of Chronic Pelvic Pain network study.
Pain. 2024 Nov 5. doi: 10.1097/j.pain.0000000000003455.
PubMed Abstract available

TIMMINS KA, Hales TG, Macfarlane GJ
Childhood maltreatment and chronic "all over" body pain in adulthood: a counterfactual analysis using UK Biobank.
Pain. 2024 Nov 5. doi: 10.1097/j.pain.0000000000003457.
PubMed Abstract available

BAUM E, Abdi S, Hattendorf J, van Eeuwijk P, et al
Burden of chronic pain among adult pastoralists in Ethiopia: a cross-sectional household survey.
Pain. 2024;165:2629-2643.
PubMed Abstract available

LI CP, Tsai RY, Chang HC, Gau SY, et al
Musculoskeletal pain during menopausal transition.
Pain. 2024;165:2655.
PubMed

HERTEL E, Ciampi de Andrade D, Kjaer-Staal Petersen K
An attempt to identify nociceptive and nociplastic pain profiles using a clinical test for joint pain.
Pain. 2024;165:2398-2400.
PubMed

HEATHCOTE LC
Pain after cancer: navigating the complexities and embracing psychological insights.
Pain. 2024;165:2396-2397.
PubMed

SLATER H, Briggs AM
Strengthening the pain care ecosystem to support equitable, person-centered, high-value musculoskeletal pain care.
Pain. 2024;165.
PubMed Abstract available

BOERNER KE, Schechter NL, Oberlander TF
Pain and development: interacting phenomena.
Pain. 2024;165.
PubMed Abstract available

HAYTHORNTHWAITE JA, Campbell CM, Edwards RR
When thinking about pain contributes to suffering: the example of pain catastrophizing.
Pain. 2024;165.
PubMed Abstract available

LOGGIA ML
"Neuroinflammation": does it have a role in chronic pain? Evidence from human imaging.
Pain. 2024;165.
PubMed Abstract available

KOSEK E
The concept of nociplastic pain-where to from here?
Pain. 2024;165.
PubMed Abstract available

CARDOSA MS
Promoting multidisciplinary pain management in low- and middle-income countries-challenges and achievements.
Pain. 2024;165.
PubMed Abstract available

FITZGERALD M
On the relation of injury to pain-an infant perspective.
Pain. 2024;165.
PubMed Abstract available

LANGEVIN HM
Addressing gaps in pain research from an integrated whole person perspective.
Pain. 2024;165.
PubMed Abstract available

LOBBEZOO F, Parisius KGH, Verhoeff MC
Orofacial pain and dysfunction in patients with special needs, with a focus on interdisciplinarity.
Pain. 2024;165.
PubMed Abstract available

BALLANTYNE JC, Basbaum AI
It all began in Issaquah 50 years ago.
Pain. 2024;165.
PubMed Abstract available

STERLING M, Davis KD
Introduction to the biennial review of pain.
Pain. 2024;165.
PubMed

October 2024

ROMAN-JUAN J, Ceniza-Bordallo G, Sanchez-Rodriguez E, Jensen MP, et al
Fatigue, sleep disturbance, and pain interference in children and adolescents with chronic pain: a longitudinal study.
Pain. 2024 Oct 30. doi: 10.1097/j.pain.0000000000003432.
PubMed Abstract available

GOMEZ K, Calderon-Rivera A, Khanna R
Pain's puzzle pieces: MAGI-1, NaV1.8, degradation, analgesia.
Pain. 2024 Oct 30. doi: 10.1097/j.pain.0000000000003471.
PubMed

AKERLUND M, Baskozos G, Li W, Themistocleous AC, et al
Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort.
Pain. 2024 Oct 29. doi: 10.1097/j.pain.0000000000003463.
PubMed Abstract available

VAN OOSTERWIJCK S, Billens A, Cnockaert E, Danneels L, et al
Spinal hyperexcitability in patients with chronic musculoskeletal pain or headache as evidenced by alterations in the nociceptive withdrawal reflex: a systematic review and meta-analysis.
Pain. 2024 Oct 29. doi: 10.1097/j.pain.0000000000003436.
PubMed Abstract available

JANI M, Girard N, Bates DW, Buckeridge DL, et al
Comparative risk of mortality in new users of prescription opioids for noncancer pain: results from the International Pharmacosurveillance Study.
Pain. 2024 Oct 29. doi: 10.1097/j.pain.0000000000003446.
PubMed Abstract available

HUERTA MA, Molina-Alvarez M, Garcia MM, Tejada MA, et al
The role of neutrophils in pain: systematic review and meta-analysis of animal studies.
Pain. 2024 Oct 25. doi: 10.1097/j.pain.0000000000003450.
PubMed Abstract available

SHI WG, Yao Y, Liang YJ, Lei J, et al
Activation of TGR5 in the injured nerve site according to a prevention protocol mitigates partial sciatic nerve ligation-induced neuropathic pain by alleviating neuroinflammation.
Pain. 2024 Oct 25. doi: 10.1097/j.pain.0000000000003460.
PubMed Abstract available

RAMIREZ MEDINA CR, Lyon M, Davies E, McCarthy D, et al
Clinical indications associated with new opioid use for pain management in the United Kingdom: using national primary care data.
Pain. 2024 Oct 24. doi: 10.1097/j.pain.0000000000003402.
PubMed Abstract available

YANG J, Xie YF, Smith R, Ratte S, et al
Discordance between preclinical and clinical testing of NaV1.7-selective inhibitors for pain.
Pain. 2024 Oct 23. doi: 10.1097/j.pain.0000000000003425.
PubMed Abstract available

KLEM NR, Slater H, Rowbotham S, Chua J, et al
Lived and care experiences of young people with chronic musculoskeletal pain and mental health conditions. A systematic review with qualitative evidence synthesis.
Pain. 2024 Oct 22. doi: 10.1097/j.pain.0000000000003407.
PubMed Abstract available

PENTIADO JUNIOR JAM, Barbosa MM, Kubota GT, Martins PN, et al
METHA-NeP: effectiveness and safety of methadone for neuropathic pain: a controlled randomized trial.
Pain. 2024 Oct 22. doi: 10.1097/j.pain.0000000000003413.
PubMed Abstract available

TOYE F, Hannink E, Woolverton A, Barker KL, et al
Understanding what it is like to experience pain as you grow up: a poetic meta-ethnography.
Pain. 2024 Oct 18. doi: 10.1097/j.pain.0000000000003420.
PubMed Abstract available

O'BRIEN MS, Richter E, Woodward T, Bradshaw HB, et al
Visual exposure to green light therapy reduces knee joint pain and alters the lipidome in osteoarthritic rats.
Pain. 2024 Oct 18. doi: 10.1097/j.pain.0000000000003458.
PubMed Abstract available

SCHMELZ M
Peripheral or central origin of chronic pain? Mu!
Pain. 2024 Oct 17. doi: 10.1097/j.pain.0000000000003444.
PubMed

LI X, Jin R, Lu X, Zhan Y, et al
Alpha transcranial alternating current stimulation modulates pain anticipation and perception in a context-dependent manner.
Pain. 2024 Oct 16. doi: 10.1097/j.pain.0000000000003452.
PubMed Abstract available

LEECH KA, Kettlety SA, Mack WJ, Kreder KJ, et al
Brain predicted age in chronic pelvic pain: a study by the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network.
Pain. 2024 Oct 16. doi: 10.1097/j.pain.0000000000003424.
PubMed Abstract available

VILLA S, Aasvang EK, Attal N, Baron R, et al
Harmonizing neuropathic pain research: outcomes of the London consensus meeting on peripheral tissue studies.
Pain. 2024 Oct 16. doi: 10.1097/j.pain.0000000000003445.
PubMed Abstract available

EATHER CE, Sterling M, Sullivan C, Elphinston RA, et al
Leveraging value-based health principles to improve translation and impact of digital psychological interventions for people with chronic pain.
Pain. 2024 Oct 15. doi: 10.1097/j.pain.0000000000003441.
PubMed

GRANVIKEN F, Meisingset I, Bach K, Bones AF, et al
Personalised decision support in the management of patients with musculoskeletal pain in primary physiotherapy care: a cluster randomised controlled trial (the SupportPrim project).
Pain. 2024 Oct 15. doi: 10.1097/j.pain.0000000000003456.
PubMed Abstract available

CHEN X, Mi W, Gao T, Ding F, et al
Astrocytes in the rostral ventromedial medulla mediate the analgesic effect of electroacupuncture in a rodent model of chemotherapy-induced peripheral neuropathic pain.
Pain. 2024 Oct 15. doi: 10.1097/j.pain.0000000000003433.
PubMed Abstract available

GILRON I, Xiao MZX, Carley M, Salter MW, et al
Glial-modulating agents for the treatment of pain: a systematic review.
Pain. 2024 Oct 15. doi: 10.1097/j.pain.0000000000003447.
PubMed Abstract available

MORRIS MC, Moradi H, Aslani M, Sun S, et al
Haves and have-nots: socioeconomic position improves accuracy of machine learning algorithms for predicting high-impact chronic pain.
Pain. 2024 Oct 11. doi: 10.1097/j.pain.0000000000003451.
PubMed Abstract available

ZHAI M, Peng B, Zhu H, Xiao J, et al
Wnt5a/Ryk signaling contributes to bone cancer pain by sensitizing the peripheral nociceptors through JNK-mediated TRPV1 pathway in rats.
Pain. 2024 Oct 8. doi: 10.1097/j.pain.0000000000003426.
PubMed Abstract available

ZHOU F, Engel P, Ruth P, Lukowski R, et al
Slack potassium channels in spinal dorsal horn neurons control neuropathic pain and acute itch.
Pain. 2024 Oct 8. doi: 10.1097/j.pain.0000000000003427.
PubMed Abstract available

ALVES-SIMOES M, Teege L, Tomni C, Lurkens M, et al
NaV1.8/NaV1.9 double deletion mildly affects acute pain responses in mice.
Pain. 2024 Oct 4. doi: 10.1097/j.pain.0000000000003411.
PubMed Abstract available

ZHAO W, Lu X, Tu Y
Child maltreatment elevated the risk of late-life chronic pain: a biopsychosocial framework from the UK Biobank cohort.
Pain. 2024 Oct 3. doi: 10.1097/j.pain.0000000000003417.
PubMed Abstract available

ROMAN-JUAN J, Sole E, Sanchez-Rodriguez E, Castarlenas E, et al
The revised pediatric chronic pain grading: built on outdated foundations, overlooking newer pediatric versions.
Pain. 2024;165:2389-2390.
PubMed

WIDEMAN TH, Stilwell P, Gagnon-Mailhot M, Hudon A, et al
Defining pain-related suffering requires partnership with people living with pain and careful critical thought: a commentary on the proposed definition by Noe-Steinmuller et al.
Pain. 2024;165:2387.
PubMed

ADAMCZYK WM, Szikszay TM
Spatial illusion of pain: the influence of nociception on body ownership.
Pain. 2024;165:2139-2140.
PubMed

OLIVA V, Riegner G, Dean J, Khatib LA, et al
I feel your pain: higher empathy is associated with higher posterior default mode network activity.
Pain. 2024 Oct 1. doi: 10.1097/j.pain.0000000000003434.
PubMed Abstract available

September 2024

DAGENAIS P, Courteau M, Courteau J, Martel G, et al
Care trajectories for musculoskeletal disorders following a new episode of low back pain.
Pain. 2024 Sep 27. doi: 10.1097/j.pain.0000000000003409.
PubMed Abstract available

RAMON-GONEN R, Granovsky Y, Shelly S
Predicting chronic post-traumatic head and neck pain: the role of bedside parameters.
Pain. 2024 Sep 27. doi: 10.1097/j.pain.0000000000003431.
PubMed Abstract available

MORADO-URBINA CE, Kato J, Sandor K, Vazquez-Mora JA, et al
Sex-dependent effects of the targeted NGF mutation (R100E) on pain behavior, joint inflammation, and bone erosion in mice.
Pain. 2024 Sep 25. doi: 10.1097/j.pain.0000000000003343.
PubMed Abstract available

LEE DH, Lee S, Woo CW
Decoding pain: uncovering the factors that affect the performance of neuroimaging-based pain models.
Pain. 2024 Sep 25. doi: 10.1097/j.pain.0000000000003392.
PubMed Abstract available

RAVEH A, Pen Y, Silberman A, Peretz A, et al
Dual Kv7.2/3-TRPV1 modulators inhibit nociceptor hyperexcitability and alleviate pain without target-related side effects.
Pain. 2024 Sep 24. doi: 10.1097/j.pain.0000000000003390.
PubMed Abstract available

MARTIN LF, Almuslim M, Ismail KA, Ibrahim MM, et al
The conotoxin Contulakin-G reverses hypersensitivity observed in rodent models of cancer-induced bone pain without inducing tolerance or motor disturbance.
Pain. 2024 Sep 19. doi: 10.1097/j.pain.0000000000003391.
PubMed Abstract available

DIB-HAJJ SD, Waxman SG
Species-specific differences and the role of Nav1.9 in pain pathophysiology.
Pain. 2024 Sep 19. doi: 10.1097/j.pain.0000000000003395.
PubMed

GIORDANO R, Arendt-Nielsen L, Gerra MC, Kappel A, et al
Pain mechanistic networks: the development using supervised multivariate data analysis and implications for chronic pain.
Pain. 2024 Sep 18. doi: 10.1097/j.pain.0000000000003410.
PubMed Abstract available

PHILLIPS N, Brown BT, Jones MP, Magson N, et al
The association between bullying victimization and back pain in young people: a systematic literature review and meta-analysis.
Pain. 2024 Sep 18. doi: 10.1097/j.pain.0000000000003398.
PubMed Abstract available

PAPADOMANOLAKIS-PAKIS N, Haroutounian S, Sorensen JK, Runge C, et al
Development and internal validation of a clinical risk tool to predict chronic postsurgical pain in adults: a prospective multicentre cohort study.
Pain. 2024 Sep 18. doi: 10.1097/j.pain.0000000000003405.
PubMed Abstract available

ROSA-CASILLAS M, Basbaum AI
Rostral ventral medulla circuits regulate both the sensory and affective dimensions of neuropathic pain: a commentary on Dogrul et al.
Pain. 2024 Sep 18. doi: 10.1097/j.pain.0000000000003375.
PubMed

GILRON I
Randomized controlled trials of pain treatment: essential research tools, a framework for clinical care.
Pain. 2024 Sep 18. doi: 10.1097/j.pain.0000000000003414.
PubMed

PLONER M
Developing neuroimaging-based biomarkers of pain: systematic and coordinated approaches.
Pain. 2024 Sep 17. doi: 10.1097/j.pain.0000000000003393.
PubMed

SON E, Gaither R, Lobo J, Zhao Y, et al
Further evidence that peritraumatic 17beta-estradiol levels influence chronic posttraumatic pain outcomes in women, data from both humans and animals.
Pain. 2024 Sep 13. doi: 10.1097/j.pain.0000000000003408.
PubMed Abstract available

HU XY, Young B, Santer M, Everitt H, et al
Self-management interventions for chronic widespread pain including fibromyalgia: a systematic review and qualitative evidence synthesis.
Pain. 2024 Sep 12. doi: 10.1097/j.pain.0000000000003379.
PubMed Abstract available

PRATT ML, Plumb AN, Manjrekar A, Cardona LM, et al
Microbiome contributions to pain: a review of the preclinical literature.
Pain. 2024 Sep 10. doi: 10.1097/j.pain.0000000000003376.
PubMed Abstract available

RAU LM, Korwisi B, Barke A, Frosch M, et al
11th revision of the International Classification of Diseases chronic primary pain diagnoses in children and adolescents: representation of pediatric patients in the new classification system.
Pain. 2024 Sep 6. doi: 10.1097/j.pain.0000000000003386.
PubMed Abstract available

YOUNG CC, Enichen E, Rao A, Succi MD, et al
Racial, ethnic, and sex bias in large language model opioid recommendations for pain management.
Pain. 2024 Sep 6. doi: 10.1097/j.pain.0000000000003388.
PubMed Abstract available

LENDARO E, Van der Sluis CK, Hermansson L, Bunketorp-Kall L, et al
Extended reality used in the treatment of phantom limb pain: a multicenter, double-blind, randomized controlled trial.
Pain. 2024 Sep 5. doi: 10.1097/j.pain.0000000000003384.
PubMed Abstract available

BUCHMAN DZ
AI and the ethics of techno-solutionism in pain management.
Pain. 2024 Sep 5. doi: 10.1097/j.pain.0000000000003389.
PubMed

GAUNTLETT-GILBERT J, Greco C
More work to do: ICD-11 pain diagnoses in children.
Pain. 2024 Sep 3. doi: 10.1097/j.pain.0000000000003387.
PubMed

AYOUB LJ, Honigman L, Barnett AJ, McAndrews MP, et al
Mechanical pain sensitivity is associated with hippocampal structural integrity.
Pain. 2024;165:2079-2086.
PubMed Abstract available

DEVOR M
An alternative perspective on the causes of pain in osteoarthritis of the knee and its persistence after total knee replacement surgery.
Pain. 2024;165:2135.
PubMed

KARRI J, Cohen SP
Dilemmas with denervation: to do or not to do (that is the question).
Pain. 2024;165:1904-1906.
PubMed

PHAM QTT, Weng HJ
Uncovering the missing mutations in pain.
Pain. 2024;165:1901-1903.
PubMed

FINAN PH
Advances in the analysis of intensive longitudinal pain data: a commentary on Leroux et al.
Pain. 2024;165:1895-1896.
PubMed

LIU Y, Sun J, Wu C, Ren J, et al
Characterizing the opioidergic mechanisms of repetitive transcranial magnetic stimulation-induced analgesia: a randomized controlled trial.
Pain. 2024;165:2035-2043.
PubMed Abstract available

August 2024

GERHART J, Burns JW, Thorn B, Jensen M, et al
Treatment mechanism and outcome decoupling effects in cognitive therapy, mindfulness-based stress reduction, and behavior therapy for chronic pain.
Pain. 2024 Aug 30. doi: 10.1097/j.pain.0000000000003374.
PubMed Abstract available

LI C, Liu C, Ye C, Lian Z, et al
Education, gender, and frequent pain among middle-aged and older adults in the United States, England, China, and India.
Pain. 2024 Aug 26. doi: 10.1097/j.pain.0000000000003349.
PubMed Abstract available

SCHMIDT H, Drusko A, Renz MP, Schlomp L, et al
Application of the grading system for "nociplastic pain" in chronic primary and chronic secondary pain conditions: a field study.
Pain. 2024 Aug 26. doi: 10.1097/j.pain.0000000000003355.
PubMed Abstract available

FJELD MK, Arnes AP, Engdahl B, Morseth B, et al
The physical activity paradox; exploring the relationship with pain outcomes. The Tromso Study 2015-2016.
Pain. 2024 Aug 26. doi: 10.1097/j.pain.0000000000003344.
PubMed Abstract available

SGOURDOU P, Schaffler M, Choi K, McCall NM, et al
Impaired pain in mice lacking first-order posterior medial thalamic neurons.
Pain. 2024 Aug 23. doi: 10.1097/j.pain.0000000000003325.
PubMed Abstract available

KOECHLIN H, Locher C, Barke A, Korwisi B, et al
Retrospective identification of the diagnosis of chronic primary musculoskeletal pain: a pragmatic suggestion by The Pain Net.
Pain. 2024 Aug 22. doi: 10.1097/j.pain.0000000000003380.
PubMed

BAUTIN P, Fortier MA, Sean M, Little G, et al
What has brain diffusion magnetic resonance imaging taught us about chronic primary pain: a narrative review.
Pain. 2024 Aug 21. doi: 10.1097/j.pain.0000000000003345.
PubMed Abstract available

RUBENSTEIN D, Green MJ, Sweitzer MM, Keefe FJ, et al
Bidirectional relationships between pain and patterns of cannabis and tobacco use in a US nationally representative sample.
Pain. 2024 Aug 21. doi: 10.1097/j.pain.0000000000003381.
PubMed Abstract available

BIGGS EE, Timmers I, Heathcote LC, Tremblay-McGaw AG, et al
Emotional memory bias in adolescents with chronic pain: examining the relationship with neural, stress, and psychological factors.
Pain. 2024 Aug 21. doi: 10.1097/j.pain.0000000000003382.
PubMed Abstract available

NEUMANN N, Domin M, Lotze M
Gray matter volume of limbic brain structures during the development of chronic back pain: a longitudinal cohort study.
Pain. 2024 Aug 20. doi: 10.1097/j.pain.0000000000003351.
PubMed Abstract available

GIERE C, Thevenot A, Menger Y, Gazzo G, et al
Between Scylla and Charybdis: assessing the multidimensional aspects of pain behaviors in rats using a double avoidance place preference paradigm.
Pain. 2024 Aug 20. doi: 10.1097/j.pain.0000000000003383.
PubMed Abstract available

RAGHURAMAN N, Colloca L
Expectations and transcranial direct current stimulation-induced brain modulation: independent and additive effects on experimental pain.
Pain. 2024 Aug 15. doi: 10.1097/j.pain.0000000000003339.
PubMed

GOEBEL A
Nociplastic pain-grading the unknown.
Pain. 2024 Aug 9. doi: 10.1097/j.pain.0000000000003356.
PubMed

DU L, Zhu J, Liu S, Yang W, et al
Transient receptor potential melastatin 8 contributes to the interleukin-33-mediated cold allodynia in a mouse model of neuropathic pain.
Pain. 2024 Aug 8. doi: 10.1097/j.pain.0000000000003346.
PubMed Abstract available

RADER L, Wager TD, Friedman NP
Chronic pain is specifically associated with updating working memory: a longitudinal twin study.
Pain. 2024 Aug 6. doi: 10.1097/j.pain.0000000000003347.
PubMed Abstract available

SCHOLTEN S, Herzog P, Glombiewski JA, Kaiser T, et al
Is personalization of psychological pain treatments necessary? Evidence from a Bayesian variance ratio meta-analysis.
Pain. 2024 Aug 2. doi: 10.1097/j.pain.0000000000003363.
PubMed Abstract available

YANG QH, Lu JY
Enhancing virtual reality for chronic pain management.
Pain. 2024;165:1892.
PubMed

KAJIWARA K, Kako J, Ito Y, Tsubaki M, et al
The effect of music-based caregiving intervention on pain intensity in nursing home patients with dementia.
Pain. 2024;165:1890.
PubMed

ECCLESTON C, Fisher E, Keefe FJ, Palermo TM, et al
Digital therapeutics and behavioral chronic pain management: closing the gap between innovation and effective use.
Pain. 2024 Aug 1. doi: 10.1097/j.pain.0000000000003348.
PubMed

July 2024

SYPEK EI, Tassou A, Collins HY, Huang K, et al
Diversity of microglial transcriptional responses during opioid exposure and neuropathic pain.
Pain. 2024 Jul 30. doi: 10.1097/j.pain.0000000000003275.
PubMed Abstract available

WALLWORK SB, Shenk C, McMurtry CM, Hood AM, et al
"I hear you". Validation in the context of children's pain as an untapped opportunity to prevent chronic pain.
Pain. 2024 Jul 30. doi: 10.1097/j.pain.0000000000003350.
PubMed

DE LA ROSA JS, Brady BR, Herder KE, Wallace JS, et al
The unmet mental health needs of U.S. adults living with chronic pain.
Pain. 2024 Jul 30. doi: 10.1097/j.pain.0000000000003340.
PubMed Abstract available

RIIS TS, Feldman DA, Losser AJ, Okifuji A, et al
Noninvasive targeted modulation of pain circuits with focused ultrasonic waves.
Pain. 2024 Jul 30. doi: 10.1097/j.pain.0000000000003322.
PubMed Abstract available

FREYNHAGEN R, Fullen BM, Reneman MF, Treede RD, et al
Functioning in chronic pain: a call for a global definition.
Pain. 2024 Jul 30. doi: 10.1097/j.pain.0000000000003307.
PubMed

DOGRUL BN, Machado Kopruszinski C, Dolatyari Eslami M, Watanabe M, et al
Descending facilitation from rostral ventromedial medulla mu opioid receptor-expressing neurons is necessary for maintenance of sensory and affective dimensions of chronic neuropathic pain.
Pain. 2024 Jul 26. doi: 10.1097/j.pain.0000000000003360.
PubMed Abstract available

QUIDE Y, Jahanshad N, Andoh J, Antoniou G, et al
ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain.
Pain. 2024 Jul 26. doi: 10.1097/j.pain.0000000000003317.
PubMed

LUND CI, Rosseland LA, Steingrimsdottir OA, Engdahl BL, et al
How is age at menopause and reproductive lifespan associated with chronic pain outcomes in postmenopausal women?
Pain. 2024 Jul 26. doi: 10.1097/j.pain.0000000000003333.
PubMed Abstract available

HESTEHAVE S, Allen HN, Gomez K, Duran P, et al
Small molecule targeting NaV1.7 via inhibition of CRMP2-Ubc9 interaction reduces pain-related outcomes in a rodent osteoarthritic model.
Pain. 2024 Jul 26. doi: 10.1097/j.pain.0000000000003357.
PubMed Abstract available

MCDOUGALL JJ
NaViGating arthritis pain.
Pain. 2024 Jul 25. doi: 10.1097/j.pain.0000000000003358.
PubMed

TOZZO MC, Reis FJJ, Alaiti RK, Hotta GH, et al
Association between perception of harm and valence of shoulder movement images with disability levels related to chronic shoulder pain.
Pain. 2024 Jul 23. doi: 10.1097/j.pain.0000000000003337.
PubMed Abstract available

MASER D, Mussgens D, Kleine-Borgmann J, Kincses B, et al
Setting the stage for pain relief: how treatment setting impacts interdisciplinary multimodal pain treatment for patients with chronic back pain.
Pain. 2024 Jul 19. doi: 10.1097/j.pain.0000000000003318.
PubMed Abstract available

PAYNE LA, Seidman LC, Napadow V, Nickerson LD, et al
Functional connectivity associations with menstrual pain characteristics in adolescents: an investigation of the triple network model.
Pain. 2024 Jul 18. doi: 10.1097/j.pain.0000000000003334.
PubMed Abstract available

CROFT P, Hill JC, Foster NE, Dunn KM, et al
Stratified health care for low back pain using the STarT Back approach: Holy Grail or doomed to fail?
Pain. 2024 Jul 18. doi: 10.1097/j.pain.0000000000003319.
PubMed Abstract available

DEHGHANI A, Bango C, Murphy EK, Halter RJ, et al
Independent effects of transcranial direct current stimulation and social influence on pain.
Pain. 2024 Jul 12. doi: 10.1097/j.pain.0000000000003338.
PubMed Abstract available

RAJI MA, Shah R, Westra JR, Kuo YF, et al
Central nervous system active medication use in Medicare enrollees receiving home health care: association with chronic pain and anxiety level.
Pain. 2024 Jul 10. doi: 10.1097/j.pain.0000000000003331.
PubMed Abstract available

JIN S, Cho HJ
Cerebral hemodynamics as biomarkers for neuropathic pain in rats: a longitudinal study using a spinal nerve ligation model.
Pain. 2024 Jul 10. doi: 10.1097/j.pain.0000000000003332.
PubMed Abstract available

HEUKAMP NJ, Moliadze V, Misic M, Usai K, et al
Beyond the chronic pain stage: default mode network perturbation depends on years lived with back pain.
Pain. 2024 Jul 10. doi: 10.1097/j.pain.0000000000003335.
PubMed Abstract available

CENIZA-BORDALLO G, Gomez Fraile A, Martin-Casas P, Rabbitts JA, et al
Prevalence, pain trajectories, and presurgical predictors for chronic postsurgical pain in a pediatric sample in Spain with a 24-month follow-up.
Pain. 2024 Jul 10. doi: 10.1097/j.pain.0000000000003330.
PubMed Abstract available

OCAY DD, Lobo K, Kim A, Halpin M, et al
Development and validation of a home quantitative sensory testing tool-kit to assess changes in sensory and pain processing: a study in healthy young adults.
Pain. 2024 Jul 9. doi: 10.1097/j.pain.0000000000003320.
PubMed Abstract available

RYAN E, Grol-Prokopczyk H, Dennison CR, Zajacova A, et al
Is the relationship between chronic pain and mortality causal? A propensity score analysis.
Pain. 2024 Jul 9. doi: 10.1097/j.pain.0000000000003336.
PubMed Abstract available

ALBERTS NM, Leisenring W, Whitton J, Stratton K, et al
Characterization of chronic pain, pain interference, and daily pain experiences in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study.
Pain. 2024 Jul 9. doi: 10.1097/j.pain.0000000000003284.
PubMed Abstract available

FEINSTEIN AB, Brown K, Dunn AL, Neville AJ, et al
Where do we start? Health care transition in adolescents and young adults with chronic primary pain.
Pain. 2024 Jul 9. doi: 10.1097/j.pain.0000000000003324.
PubMed

LEESE C, Gupte D, Christogianni A, Higgins C, et al
Barriers and facilitators for physical activity in people living with chronic pain: a systematic review and combined analysis.
Pain. 2024 Jul 9. doi: 10.1097/j.pain.0000000000003314.
PubMed Abstract available

GIERTHMUHLEN J, Attal N, Baskozos G, Bennedsgaard K, et al
What is associated with painful polyneuropathy? A cross-sectional analysis of symptoms and signs in patients with painful and painless polyneuropathy.
Pain. 2024 Jul 3. doi: 10.1097/j.pain.0000000000003310.
PubMed Abstract available

LIN N, Cavaleri R, Rio E, Stanton TR, et al
The relationship between sustained hamstring pain and reorganisation of somatosensory representations: a randomised, controlled study.
Pain. 2024 Jul 2. doi: 10.1097/j.pain.0000000000003312.
PubMed Abstract available

ROSENBERGER DC, Mennicken E, Schmieg I, Medkour T, et al
A systematic literature review on patient-reported outcome domains and measures in nonsurgical efficacy trials related to chronic pain associated with endometriosis: an urgent call to action.
Pain. 2024 Jul 2. doi: 10.1097/j.pain.0000000000003290.
PubMed Abstract available

FRANCIOSA F, Acuna MA, Nevian NE, Nevian T, et al
A cellular mechanism contributing to pain-induced analgesia.
Pain. 2024 Jul 2. doi: 10.1097/j.pain.0000000000003315.
PubMed Abstract available

ROSENSTROM AHC, Ahmed AS, Kultima K, Freyhult E, et al
Unraveling the neuroimmune interface in chronic pain-the association between cytokines in the cerebrospinal fluid and pain in patients with lumbar disk herniation or degenerative disk disease.
Pain. 2024;165:e65-e79.
PubMed Abstract available

Comparing the prevalence of chronic pain in school-aged children in the United States from 2019 to 2020: a nationally representative study examining differences associated with the COVID-19 pandemic: erratum.
Pain. 2024;165:1655.
PubMed

MEHLING K, Becker J, Chen J, Scriba S, et al
Bilateral deficiency of Meissner corpuscles and papillary microvessels in patients with acute complex regional pain syndrome.
Pain. 2024;165:1613-1624.
PubMed Abstract available

June 2024

KAYA B, Boerner KE, Lord RC, Potter E, et al
Body image, sex, gender, and pain: towards an improved understanding of pain mechanisms.
Pain. 2024 Jun 28. doi: 10.1097/j.pain.0000000000003309.
PubMed

MURRAY CB, Li R, Kashikar-Zuck S, Zhou C, et al
Adolescent predictors of young adult pain and health outcomes: results from a 6-year prospective follow-up study.
Pain. 2024 Jun 25. doi: 10.1097/j.pain.0000000000003308.
PubMed Abstract available

WILSON MV, Braithwaite FA, Arnold JB, Crouch SM, et al
The effectiveness of peer support interventions for community-dwelling adults with chronic musculoskeletal pain: a systematic review and meta-analysis of randomised trials.
Pain. 2024 Jun 25. doi: 10.1097/j.pain.0000000000003293.
PubMed Abstract available

BETTI S, Badioli M, Dalbagno D, Garofalo S, et al
Topographically selective motor inhibition under threat of pain.
Pain. 2024 Jun 22. doi: 10.1097/j.pain.0000000000003301.
PubMed Abstract available

CHENG S, Cao J, Hou L, Li S, et al
Temporal trends and projections in the global burden of neck pain: findings from the Global Burden of Disease Study 2019.
Pain. 2024 Jun 19. doi: 10.1097/j.pain.0000000000003298.
PubMed Abstract available

BERUBE M, Verret M, Bourque L, Cote C, et al
Educational needs and preferences of adult patients with acute pain: a mixed-methods systematic review.
Pain. 2024 Jun 18. doi: 10.1097/j.pain.0000000000003288.
PubMed Abstract available

RUTTER-LOCHER Z, Norton S, Denk F, McMahon S, et al
A randomised controlled trial of the effect of intra-articular lidocaine on pain scores in inflammatory arthritis.
Pain. 2024 Jun 17. doi: 10.1097/j.pain.0000000000003291.
PubMed Abstract available

MILLER A, Candido KD, Knezevic NN, Rivera J, et al
A randomized, placebo-controlled trial of long-acting dexamethasone viscous gel delivered by transforaminal injection for lumbosacral radicular pain.
Pain. 2024 Jun 14. doi: 10.1097/j.pain.0000000000003287.
PubMed Abstract available

ATTAL N, Branders S, Pereira A, Bouhassira D, et al
Prediction of the response to repetitive transcranial magnetic stimulation of the motor cortex in peripheral neuropathic pain and validation of a new algorithm.
Pain. 2024 Jun 14. doi: 10.1097/j.pain.0000000000003297.
PubMed Abstract available

BAUM E, Abdi S, Hattendorf J, van Eeuwijk P, et al
Burden of chronic pain among adult pastoralists in Ethiopia: a cross-sectional household survey.
Pain. 2024 Jun 5. doi: 10.1097/j.pain.0000000000003282.
PubMed Abstract available

FISHER E, Monsell F, Clinch J, Eccleston C, et al
Who develops chronic pain after an acute lower limb injury? A longitudinal study of children and adolescents.
Pain. 2024 Jun 5. doi: 10.1097/j.pain.0000000000003274.
PubMed Abstract available

LONG-MILLS E, Tumin D
Pediatric chronic pain and exposure to bullying as perpetrator or victim.
Pain. 2024;165:1425.
PubMed

FERLAND S, Wang F, De Koninck Y, Ferrini F, et al
An improved conflict avoidance assay reveals modality-specific differences in pain hypersensitivity across sexes.
Pain. 2024;165:1304-1316.
PubMed Abstract available

May 2024

LI S, Ren X, Guan Y, Zhao F, et al
Genetic etiology study in a large cohort with congenital insensitivity to pain with anhidrosis.
Pain. 2024 May 31. doi: 10.1097/j.pain.0000000000003252.
PubMed Abstract available

LI R, Groenewald C, Tham SW, Rabbitts JA, et al
Influence of chronotype on pain incidence during early adolescence.
Pain. 2024 May 28. doi: 10.1097/j.pain.0000000000003271.
PubMed Abstract available

RUNGE N, Ahmed I, Saueressig T, Perea J, et al
The bidirectional relationship between sleep problems and chronic musculoskeletal pain: a systematic review with meta-analysis.
Pain. 2024 May 28. doi: 10.1097/j.pain.0000000000003279.
PubMed Abstract available

HUBNER FCL, Telles RW, Giatti L, Machado LAC, et al
Job stress and chronic low back pain: incidence, number of episodes, and severity in a 4-year follow-up of the ELSA-Brasil Musculoskeletal cohort.
Pain. 2024 May 24. doi: 10.1097/j.pain.0000000000003276.
PubMed Abstract available

HUANG F, Fan Y, Tang R, Xie Z, et al
Musculoskeletal pain among Chinese women during the menopausal transition: findings from a longitudinal cohort study.
Pain. 2024 May 23. doi: 10.1097/j.pain.0000000000003283.
PubMed Abstract available

JAGTIANI A, Chou E, Gillespie SE, Liu K, et al
High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES).
Pain. 2024 May 23. doi: 10.1097/j.pain.0000000000003262.
PubMed Abstract available

YOO CH, Rani N, Shen S, Loggia ML, et al
Investigating neuroepigenetic alterations in chronic low back pain with positron emission tomography.
Pain. 2024 May 21. doi: 10.1097/j.pain.0000000000003272.
PubMed Abstract available

HICKLING LM, Allani S, Cella M, Scott W, et al
A systematic review with meta-analyses of the association between stigma and chronic pain outcomes.
Pain. 2024 May 16. doi: 10.1097/j.pain.0000000000003243.
PubMed Abstract available

CHANG NHS, Nim C, Harsted S, Young JJ, et al
Data-driven identification of distinct pain drawing patterns and their association with clinical and psychological factors: a study of 21,123 patients with spinal pain.
Pain. 2024 May 15. doi: 10.1097/j.pain.0000000000003261.
PubMed Abstract available

CHAMBERS CT, Dol J, Tutelman PR, Langley CL, et al
The prevalence of chronic pain in children and adolescents: a systematic review update and meta-analysis.
Pain. 2024 May 15. doi: 10.1097/j.pain.0000000000003267.
PubMed Abstract available

LANGFORD DJ, Mark RP, France FO, Nishtar M, et al
Use of patient-reported global assessment measures in clinical trials of chronic pain treatments: ACTTION systematic review and considerations.
Pain. 2024 May 14. doi: 10.1097/j.pain.0000000000003270.
PubMed Abstract available

LEVY GIGI E, Rachmani M, Defrin R
The relationship between traumatic exposure and pain perception in children: the moderating role of posttraumatic symptoms.
Pain. 2024 May 8. doi: 10.1097/j.pain.0000000000003266.
PubMed Abstract available

WAUTERS A, Van Ryckeghem DML, Noel M, Mueri K, et al
Parental narrative style moderates the relation between pain-related attention and memory biases in youth with chronic pain.
Pain. 2024 May 8. doi: 10.1097/j.pain.0000000000003263.
PubMed Abstract available

TIMMERS I, Biggs EE, Bruckert L, Tremblay-McGaw AG, et al
Probing white matter microstructure in youth with chronic pain and its relation to catastrophizing using neurite orientation dispersion and density imaging.
Pain. 2024 May 8. doi: 10.1097/j.pain.0000000000003269.
PubMed Abstract available

FALCO P, Litewczuk D, Di Stefano G, Galosi E, et al
Small fibre neuropathy frequently underlies the painful long-COVID syndrome.
Pain. 2024 May 7. doi: 10.1097/j.pain.0000000000003259.
PubMed Abstract available

LEROUX A, Crainiceanu C, Zeger S, Taub M, et al
Statistical modeling of acute and chronic pain patient-reported outcomes obtained from ecological momentary assessment.
Pain. 2024 May 7. doi: 10.1097/j.pain.0000000000003214.
PubMed Abstract available

EMVALOMENOS GM, Kang JWM, Jupp B, Mychasiuk R, et al
Recent developments and challenges in positron emission tomography imaging of gliosis in chronic neuropathic pain.
Pain. 2024 May 7. doi: 10.1097/j.pain.0000000000003247.
PubMed Abstract available

RAU LM, Humberg C, Konning A, Rosenthal N, et al
Longitudinal examination of associations with the onset of pediatric chronic pain at different pain locations.
Pain. 2024 May 7. doi: 10.1097/j.pain.0000000000003237.
PubMed Abstract available

COLL MP, Walden Z, Bourgoin PA, Taylor V, et al
Pain reflects the informational value of nociceptive inputs.
Pain. 2024 May 7. doi: 10.1097/j.pain.0000000000003254.
PubMed Abstract available

HOHENSCHURZ-SCHMIDT D, Cherkin D, Rice ASC, Dworkin RH, et al
Methods for pragmatic randomized clinical trials of pain therapies: IMMPACT statement.
Pain. 2024 May 3. doi: 10.1097/j.pain.0000000000003249.
PubMed Abstract available

SCHWARZ AM, Keresztes A, Bui T, Hecksel R, et al
Terpenes from Cannabis sativa induce antinociception in a mouse model of chronic neuropathic pain via activation of adenosine A2A receptors.
Pain. 2024 May 2. doi: 10.1097/j.pain.0000000000003265.
PubMed Abstract available

KORWISI B, Hay G, Forget P, Ryan D, et al
Patients' perspective on the chronic pain classification in the 11th revision of the International Classification of Diseases (ICD-11): results from an international web-based survey.
Pain. 2024 May 2. doi: 10.1097/j.pain.0000000000003248.
PubMed Abstract available

CROMBEZ G, Kang S, Van Ryckeghem DML, De Paepe AL, et al
Reply to Cohen et al. (2024): Conditioned pain: fact or fiction?
Pain. 2024;165:1190.
PubMed

COHEN M, Quintner J, Weisman A
"Conditioned pain" remains unproven and unlikely (comment on Kang et al. PAIN 2023; 164: 2596-2605).
Pain. 2024;165:1189-1190.
PubMed

ESPOSTO M, Cioeta M
Was it "conditioned" or "suggested" pain? Reply to S. Kang et al.
Pain. 2024;165:1187.
PubMed

April 2024

PAGLIUSI M JR, Amorim-Marques AP, Lobo MK, Guimaraes FS, et al
The rostral ventromedial medulla modulates pain and depression-related behaviors caused by social stress.
Pain. 2024 Apr 23. doi: 10.1097/j.pain.0000000000003257.
PubMed Abstract available

SULLIVAN MD, de C Williams AC
The social nature of human pain.
Pain. 2024 Apr 19. doi: 10.1097/j.pain.0000000000003250.
PubMed

GILANYI YL, Shah B, Cashin AG, Gibbs MT, et al
Barriers and enablers to exercise adherence in people with nonspecific chronic low back pain: a systematic review of qualitative evidence.
Pain. 2024 Apr 16. doi: 10.1097/j.pain.0000000000003234.
PubMed Abstract available

MACINTYRE E, Braithwaite FA, Stanton TR
Painful distortions: people with painful knee osteoarthritis have biased visuospatial perception of the environment.
Pain. 2024 Apr 16. doi: 10.1097/j.pain.0000000000003231.
PubMed Abstract available

PULLING BW, Braithwaite FA, Mignone J, Butler DS, et al
People with painful knee osteoarthritis hold negative implicit attitudes towards activity.
Pain. 2024 Apr 16. doi: 10.1097/j.pain.0000000000003210.
PubMed Abstract available

LI L, Yao H, Mo R, Xu L, et al
Blocking proteinase-activated receptor 2 signaling relieves pain, suppresses nerve sprouting, improves tissue repair, and enhances analgesic effect of B vitamins in rats with Achilles tendon injury.
Pain. 2024 Apr 9. doi: 10.1097/j.pain.0000000000003229.
PubMed Abstract available

RODRIGUEZ-PALMA EJ, Huerta de la Cruz S, Islas-Espinoza AM, Castaneda-Corral G, et al
Nociplastic pain mechanisms and toll-like receptors as promising targets for its management.
Pain. 2024 Apr 5. doi: 10.1097/j.pain.0000000000003238.
PubMed Abstract available

GROTHUS S, Sommer A, Stahlschmidt L, Hirschfeld G, et al
Pediatric chronic pain grading-a revised classification of the severity of pediatric chronic pain.
Pain. 2024 Apr 5. doi: 10.1097/j.pain.0000000000003226.
PubMed Abstract available

NELSON S, Mitcheson M, Nestor B, Bosquet Enlow M, et al
Biomarkers of stress as mind-body intervention outcomes for chronic pain: an evaluation of constructs and accepted measurement.
Pain. 2024 Apr 2. doi: 10.1097/j.pain.0000000000003241.
PubMed

FLORES I, Torres-Reveron A, Navarro E, Nieves-Vazquez CI, et al
Uncovering moderators of pain perception by women with endometriosis from Latin America and Spain: the roles of sociodemographics, racial self-identity, and pain catastrophizing.
Pain. 2024 Apr 2. doi: 10.1097/j.pain.0000000000003230.
PubMed Abstract available

GHIASI M, Chang C, Shafrir AL, Vitonis AF, et al
Subgroups of pelvic pain are differentially associated with endometriosis and inflammatory comorbidities: a latent class analysis.
Pain. 2024 Apr 2. doi: 10.1097/j.pain.0000000000003218.
PubMed Abstract available

DI DONATO M, Sheehan LR, Iles R, Gray S, et al
Patterns of physiotherapy attendance in compensated Australian workers with low back pain: a retrospective cohort study.
Pain. 2024 Apr 2. doi: 10.1097/j.pain.0000000000003228.
PubMed Abstract available

March 2024

AYOUB LJ, Honigman L, Barnett AJ, McAndrews MP, et al
Mechanical pain sensitivity is associated with hippocampal structural integrity.
Pain. 2024 Mar 28. doi: 10.1097/j.pain.0000000000003221.
PubMed Abstract available

NAHMAN-AVERBUCH H, Piche M, Bannister K, Coghill RC, et al
Involvement of propriospinal processes in conditioned pain modulation.
Pain. 2024 Mar 27. doi: 10.1097/j.pain.0000000000003217.
PubMed

CORMIER A, Mueri K, Pavlova M, Hood A, et al
The sociocultural context of adolescent pain: portrayals of pain in popular adolescent media.
Pain. 2024 Mar 27. doi: 10.1097/j.pain.0000000000003216.
PubMed Abstract available

KRYPOTOS AM, Crombez G, Vlaeyen JWS
The dynamics of pain avoidance: the exploration-exploitation dilemma.
Pain. 2024 Mar 22. doi: 10.1097/j.pain.0000000000003222.
PubMed

STRIGO IA, Kadlec M, Mitchell JM, Simmons AN, et al
Identification of group differences in predictive anticipatory biasing of pain during uncertainty: preparing for the worst but hoping for the best.
Pain. 2024 Mar 15. doi: 10.1097/j.pain.0000000000003207.
PubMed Abstract available

ZHOU Y, Sun W, Fu Y, Wang J, et al
Effect of esketamine combined with pregabalin on acute postsurgical pain in patients who underwent resection of spinal neoplasms: a randomized controlled trial.
Pain. 2024 Mar 15. doi: 10.1097/j.pain.0000000000003211.
PubMed Abstract available

DUPORT A, Morel P, Leonard G, Devanne H, et al
The influence of pain and kinesiophobia on motor control of the upper limb: how pointing task paradigms can point to new avenues of understanding.
Pain. 2024 Mar 13. doi: 10.1097/j.pain.0000000000003213.
PubMed Abstract available

HELLMAN KM, Tu FF
Hal, how many types of pelvic pain are there?
Pain. 2024 Mar 12. doi: 10.1097/j.pain.0000000000003219.
PubMed

CEKO M, Baeuerle T, Webster L, Wager TD, et al
The effects of virtual reality neuroscience-based therapy on clinical and neuroimaging outcomes in patients with chronic back pain: a randomized clinical trial.
Pain. 2024 Mar 8. doi: 10.1097/j.pain.0000000000003198.
PubMed Abstract available

CHEN O, Jiang C, Berta T, Powell Gray B, et al
MicroRNA let-7b enhances spinal cord nociceptive synaptic transmission and induces acute and persistent pain through neuronal and microglial signaling.
Pain. 2024 Mar 6. doi: 10.1097/j.pain.0000000000003206.
PubMed Abstract available

MARDON AK, Chalmers KJ, Heathcote LC, Curtis LA, et al
"I wish I knew then what I know now" - pain science education concepts important for female persistent pelvic pain: a reflexive thematic analysis.
Pain. 2024 Mar 6. doi: 10.1097/j.pain.0000000000003205.
PubMed Abstract available

MOREAU N, Korai SA, Sepe G, Panetsos F, et al
Peripheral and central neurobiological effects of botulinum toxin A (BoNT/A) in neuropathic pain: a systematic review.
Pain. 2024 Mar 5. doi: 10.1097/j.pain.0000000000003204.
PubMed Abstract available

PATTISON LA, Cloake A, Chakrabarti S, Hilton H, et al
Digging deeper into pain: an ethological behavior assay correlating well-being in mice with human pain experience.
Pain. 2024 Mar 5. doi: 10.1097/j.pain.0000000000003190.
PubMed Abstract available

NOE-STEINMULLER N, Scherbakov D, Zhuravlyova A, Wager TD, et al
Defining suffering in pain. A systematic review on pain-related suffering using natural language processing.
Pain. 2024 Mar 5. doi: 10.1097/j.pain.0000000000003195.
PubMed Abstract available

JAMISON RN
Unlocking the secrets of daily diary data: can we improve our understanding of the reinforcing effects of pain medication?
Pain. 2024 Mar 5. doi: 10.1097/j.pain.0000000000003163.
PubMed

ARNES AP, Fjeld MK, Stigum H, Nielsen CS, et al
Does pain tolerance mediate the effect of physical activity on chronic pain in the general population? The Tromso Study.
Pain. 2024 Mar 5. doi: 10.1097/j.pain.0000000000003209.
PubMed Abstract available

WONG JJ, Cote P, Tricco AC, Watson T, et al
Characterizing high-cost healthcare users among adults with back pain in Ontario, Canada: a population-based cohort study.
Pain. 2024 Mar 5. doi: 10.1097/j.pain.0000000000003200.
PubMed Abstract available

BLOMQVIST A, Evrard HC
The thalamic projection of pain sensations to the posterior dorsal fundus in the insula: comment on Mandonnet et al.
Pain. 2024;165:e15-e16.
PubMed

FARINELLA R, Falchi F, Tavanti A, Tuoni C, et al
The genetic variant SLC2A1 -rs1105297 is associated with the differential analgesic response to a glucose-based treatment in newborns.
Pain. 2024;165:657-665.
PubMed Abstract available

February 2024

PARK M, Koh CS, Chang H, Kim TJ, et al
Low-frequency (5-Hz) stimulation of ventrolateral periaqueductal gray modulates the descending serotonergic system in the peripheral neuropathic pain.
Pain. 2024 Feb 28. doi: 10.1097/j.pain.0000000000003185.
PubMed Abstract available

PAVY F, Zaman J, Van den Noortgate W, Scarpa A, et al
The effect of unpredictability on the perception of pain: a systematic review and meta-analysis.
Pain. 2024 Feb 28. doi: 10.1097/j.pain.0000000000003199.
PubMed Abstract available

MCKERNAN LC, McGonigle T, Vandekar SN, Crofford LJ, et al
A randomized-controlled pilot trial of telemedicine-delivered cognitive-behavioral therapy tailored for interstitial cystitis/bladder pain syndrome.
Pain. 2024 Feb 27. doi: 10.1097/j.pain.0000000000003188.
PubMed

WU PY, Caceres AI, Chen J, Sokoloff J, et al
Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice.
Pain. 2024 Feb 27. doi: 10.1097/j.pain.0000000000003181.
PubMed Abstract available

HIRSCH SJ, Budig A, Husam S, Birklein F, et al
Aged females unilaterally hypersensitize, lack descending inhibition, and overexpress alpha1D adrenergic receptors in a murine posttraumatic chronic pain model.
Pain. 2024 Feb 27. doi: 10.1097/j.pain.0000000000003197.
PubMed Abstract available

KEEFE FJ, Winger JG, Kelleher SA
Pain-related suffering: new insights into what it means and new opportunities for research and clinical practice.
Pain. 2024 Feb 27. doi: 10.1097/j.pain.0000000000003196.
PubMed

STAGG AL, Madan I, Fear N, Stevens MJ, et al
Do current methods of measuring the impact of chronic pain on work reflect the experience of working-age adults? An integrated mixed-methods systematic narrative review.
Pain. 2024 Feb 20. doi: 10.1097/j.pain.0000000000003169.
PubMed Abstract available

HERTEL E, Arendt-Nielsen L, Olesen AE, Andersen MS, et al
Quantitative sensory testing, psychological factors, and quality of life as predictors of current and future pain in patients with knee osteoarthritis.
Pain. 2024 Feb 20. doi: 10.1097/j.pain.0000000000003194.
PubMed Abstract available

MEHLING K, Becker J, Chen J, Scriba S, et al
Bilateral deficiency of Meissner corpuscles and papillary microvessels in patients with acute complex regional pain syndrome.
Pain. 2024 Feb 7. doi: 10.1097/j.pain.0000000000003168.
PubMed Abstract available

SCHNEIDER P, Lautenbacher S, Kunz M
Sex differences in facial expressions of pain: results from a combined sample.
Pain. 2024 Feb 7. doi: 10.1097/j.pain.0000000000003180.
PubMed Abstract available

BURNS JW, Gerhart J, Smith DA, Porter L, et al
Concurrent and lagged associations among pain medication use, pain, and negative affect: a daily diary study of people with chronic low back pain.
Pain. 2024 Feb 7. doi: 10.1097/j.pain.0000000000003162.
PubMed Abstract available

VAN LEEUWEN GJ, van den Heuvel MM, Bindels PJE, Bierma-Zeinstra SMA, et al
Musculoskeletal pain in 13-year-old children: the generation R study.
Pain. 2024 Feb 7. doi: 10.1097/j.pain.0000000000003182.
PubMed Abstract available

CHOWDHURY AR, Graham PL, Schofield D, Costa DSJ, et al
Productivity outcomes from chronic pain management interventions in the working age population; a systematic review.
Pain. 2024 Feb 6. doi: 10.1097/j.pain.0000000000003149.
PubMed Abstract available

OVERSTREET DS, Strath LJ, Sorge RE, Thomas PA, et al
Race-specific associations: inflammatory mediators and chronic low back pain.
Pain. 2024 Feb 6. doi: 10.1097/j.pain.0000000000003154.
PubMed Abstract available

LI CP, Gau SY, Yu JT, Tsai RY, et al
Correspondence on "The dose-dependent effects of transcutaneous electrical nerve stimulation for pain relief in individuals with fibromyalgia: a systematic review and meta-analysis".
Pain. 2024;165:489-490.
PubMed

LEGON W, Strohman A, In A, Payne B, et al
Noninvasive neuromodulation of subregions of the human insula differentially affect pain processing and heart-rate variability: a within-subjects pseudo-randomized trial.
Pain. 2024 Feb 1. doi: 10.1097/j.pain.0000000000003171.
PubMed Abstract available

SALABASIDOU E, Binder T, Volkmann J, Kuzkina A, et al
Pain in Parkinson disease: a deep phenotyping study.
Pain. 2024 Feb 1. doi: 10.1097/j.pain.0000000000003173.
PubMed Abstract available

CLAUW DJ
Why don't we use a body map in every chronic pain patient yet?
Pain. 2024 Feb 1. doi: 10.1097/j.pain.0000000000003184.
PubMed

January 2024

CUENCA-MARTINEZ F, Herranz-Gomez A, Varangot-Reille C, Bajcar EA, et al
Pain memory in children: a systematic review and meta-analysis with a meta-regression.
Pain. 2024 Jan 31. doi: 10.1097/j.pain.0000000000003170.
PubMed Abstract available

FERLAND S, Wang F, De Koninck Y, Ferrini F, et al
An improved conflict avoidance assay reveals modality-specific differences in pain hypersensitivity across sexes.
Pain. 2024 Jan 26. doi: 10.1097/j.pain.0000000000003132.
PubMed Abstract available

MARTEL RD, Papafragou G, Weigand S, Rolke R, et al
Interindividual variability in cold-pressor pain sensitivity is not explained by peripheral vascular responding and generalizes to a C-nociceptor-specific pain phenotype.
Pain. 2024 Jan 26. doi: 10.1097/j.pain.0000000000003049.
PubMed Abstract available

SUN F, Zajacova A, Grol-Prokopczyk H
The geography of arthritis-attributable pain outcomes: a county-level spatial analysis.
Pain. 2024 Jan 25. doi: 10.1097/j.pain.0000000000003155.
PubMed Abstract available

VAN DER VAART M, Hauck AGV, Mansfield R, Adams E, et al
Parental experience of neonatal pain research while participating in the Parental touch trial (Petal).
Pain. 2024 Jan 25. doi: 10.1097/j.pain.0000000000003177.
PubMed Abstract available

DOMENECH-GARCIA V, Skovlund SV, Bellosta-Lopez P, Calatayud J, et al
Does the distribution of musculoskeletal pain shape the fate of long-term sick leave? A prospective cohort study with register follow-up.
Pain. 2024 Jan 24. doi: 10.1097/j.pain.0000000000003176.
PubMed Abstract available

CORMIE MA, Moayedi M
Selective noninvasive modulation of insular subregions supports differential functions in the pain experience.
Pain. 2024 Jan 23. doi: 10.1097/j.pain.0000000000003172.
PubMed

TROST Z, Sturgeon J, Agtarap S, McMinn K, et al
The impact of perceived injustice on pain and psychological outcomes after traumatic injury: a longitudinal analysis.
Pain. 2024 Jan 19. doi: 10.1097/j.pain.0000000000003160.
PubMed Abstract available

MYLIUS V, Moisset X, Rukavina K, Rosner J, et al
New ICD-11 diagnostic criteria for chronic secondary musculoskeletal pain associated with Parkinson disease.
Pain. 2024 Jan 11. doi: 10.1097/j.pain.0000000000003138.
PubMed

NAKAMURA M, Yoshimi A, Tokura T, Kimura H, et al
Duloxetine improves chronic orofacial pain and comorbid depressive symptoms in association with reduction of serotonin transporter protein through upregulation of ubiquitinated serotonin transporter protein.
Pain. 2024 Jan 11. doi: 10.1097/j.pain.0000000000003124.
PubMed Abstract available

MOORE A, Karadag P, Fisher E, Crombez G, et al
Narrative bias ("spin") is common in randomised trials and systematic reviews of cannabinoids for pain.
Pain. 2024 Jan 11. doi: 10.1097/j.pain.0000000000003140.
PubMed Abstract available

WU J, Yuan T, Fu D, Xu R, et al
An experimental model for primary neuropathic corneal pain induced by long ciliary nerve ligation in rats.
Pain. 2024 Jan 11. doi: 10.1097/j.pain.0000000000003141.
PubMed Abstract available

TOLEDO TA, Vore CN, Huber FA, Rhudy JL, et al
The effect of emotion regulation on the emotional modulation of pain and nociceptive flexion reflex.
Pain. 2024 Jan 11. doi: 10.1097/j.pain.0000000000003127.
PubMed Abstract available

VLAEYEN JWS
Wearable sensor data for chronic pain: moving forward.
Pain. 2024 Jan 11. doi: 10.1097/j.pain.0000000000003135.
PubMed

PEDERSEN JR, Strijkers R, Gerger H, Koes B, et al
Clinical improvements due to specific effects and placebo effects in conservative interventions and changes observed with no treatment in randomized controlled trials of patients with chronic nonspecific low back pain: a systematic review and meta-ana
Pain. 2024 Jan 10. doi: 10.1097/j.pain.0000000000003151.
PubMed Abstract available

LOU W, Li X, Jin R, Peng W, et al
Time-varying phase synchronization of resting-state functional magnetic resonance imaging reveals a shift toward self-referential processes during sustained pain.
Pain. 2024 Jan 9. doi: 10.1097/j.pain.0000000000003152.
PubMed Abstract available

SURI P, Heagerty PJ, Timmons A, Jensen MP, et al
Description and initial validation of a novel measure of pain intensity: the Numeric Rating Scale of Underlying Pain without concurrent Analgesic use.
Pain. 2024 Jan 2. doi: 10.1097/j.pain.0000000000003150.
PubMed Abstract available

ROMAN-JUAN J, Sanchez-Rodriguez E, Sole E, Castarlenas E, et al
Immigration background as a risk factor of chronic pain and high-impact chronic pain in children and adolescents living in Spain: differences as a function of age.
Pain. 2024 Jan 2. doi: 10.1097/j.pain.0000000000003142.
PubMed Abstract available

MYRENGET ME, Rustoen T, Myskja A, Smastuen M, et al
The effect of a music-based caregiving intervention on pain intensity in nursing home patients with dementia. A cluster-randomized controlled study.
Pain. 2024 Jan 2. doi: 10.1097/j.pain.0000000000003156.
PubMed Abstract available

VITALI D, Olugbade T, Eccleston C, Keogh E, et al
Sensing behavior change in chronic pain: A scoping review of sensor technology for use in daily life.
Pain. 2024 Jan 2. doi: 10.1097/j.pain.0000000000003134.
PubMed Abstract available

MICKLE AM, Sibille KT
Deciphering relationships between stress biomarkers and fibromyalgia syndrome with implications relevant to other chronic pain conditions.
Pain. 2024;165:243-245.
PubMed

CHARRON A, Pepino L, Malapert P, Debrauwer V, et al
Sex-related exacerbation of injury-induced mechanical hypersensitivity in GAD67 haplodeficient mice.
Pain. 2024;165:192-201.
PubMed Abstract available

December 2023

GEORGE DS, Jayaraj ND, Pacifico P, Ren D, et al
The Mas-related G protein-coupled receptor d (Mrgprd) mediates pain hypersensitivity in painful diabetic neuropathy.
Pain. 2023 Dec 22. doi: 10.1097/j.pain.0000000000003120.
PubMed Abstract available

MICLESCU A, Ronngren C, Bengtsson M, Gordh T, et al
Increased risk of persistent neuropathic pain after traumatic nerve injury and surgery for carriers of a human leukocyte antigen haplotype.
Pain. 2023 Dec 22. doi: 10.1097/j.pain.0000000000003143.
PubMed Abstract available

JUNG M, Xia T, Ilomaki J, Pearce C, et al
Opioid characteristics and nonopioid interventions associated with successful opioid taper in patients with chronic noncancer pain.
Pain. 2023 Dec 19. doi: 10.1097/j.pain.0000000000003133.
PubMed Abstract available

MARDON AK, Leake HB, Szeto K, Moseley GL, et al
Recommendations for patient education in the management of persistent pelvic pain: a systematic review of clinical practice guidelines.
Pain. 2023 Dec 19. doi: 10.1097/j.pain.0000000000003137.
PubMed Abstract available

HAROUTOUNIAN S, Holzer KJ, Kerns RD, Veasley C, et al
Patient engagement in designing, conducting, and disseminating clinical pain research: IMMPACT recommended considerations.
Pain. 2023 Dec 19. doi: 10.1097/j.pain.0000000000003121.
PubMed Abstract available

ZADRO JR, Ferreira GE, Muller R, Sousa Filho LF, et al
Education can reassure people with rotator cuff-related shoulder pain: a 3-arm, randomised, online experiment.
Pain. 2023 Dec 15. doi: 10.1097/j.pain.0000000000003102.
PubMed Abstract available

GUO F, Lin SD, Du Y, Hu TT, et al
Secondary somatosensory cortex glutamatergic innervation of the thalamus facilitates pain.
Pain. 2023 Dec 15. doi: 10.1097/j.pain.0000000000003117.
PubMed Abstract available

PALERMO TM, Li R, Birnie KA, Crombez G, et al
Updated recommendations on measures for clinical trials in pediatric chronic pain: a multiphase approach from the Core Outcomes in Pediatric Persistent Pain (Core-OPPP) Workgroup.
Pain. 2023 Dec 15. doi: 10.1097/j.pain.0000000000003105.
PubMed Abstract available

KUMAR A, Soliman N, Gan Z, Cullinan P, et al
A systematic review of the prevalence of postamputation and chronic neuropathic pain associated with combat injury in military personnel.
Pain. 2023 Dec 15. doi: 10.1097/j.pain.0000000000003094.
PubMed Abstract available

BEVERIDGE JK, Noel M, Soltani S, Neville A, et al
The association between parent mental health and pediatric chronic pain: a systematic review and meta-analysis.
Pain. 2023 Dec 6. doi: 10.1097/j.pain.0000000000003125.
PubMed Abstract available

Chronic pain among U.S. sexual minority adults who identify as gay, lesbian, bisexual, or "something else": Erratum.
Pain. 2023;164:2865.
PubMed

QUEME LF
A novel potential strategy for the treatment of inflammatory and neuropathic pain.
Pain. 2023;164:2625-2626.
PubMed

November 2023

NUNEZ-CORTES R, Salazar-Mendez J, Calatayud J, Malfliet A, et al
The optimal dose of pain neuroscience education added to an exercise programme for patients with chronic spinal pain: A systematic review and dose-response meta-analysis.
Pain. 2023 Nov 30. doi: 10.1097/j.pain.0000000000003126.
PubMed Abstract available

FITZCHARLES MA, Cohen SP, Hauser W
A step towards better understanding chronic overlapping pain conditions.
Pain. 2023 Nov 30. doi: 10.1097/j.pain.0000000000003129.
PubMed

HO RLM, Park J, Wang WE, Thomas JS, et al
Lower individual alpha frequency in individuals with chronic low back pain and fear of movement.
Pain. 2023 Nov 29. doi: 10.1097/j.pain.0000000000003098.
PubMed Abstract available

AO X, Parisien M, Fillingim RB, Ohrbach R, et al
Whole-genome methylation profiling reveals regions associated with painful temporomandibular disorders and active recovery processes.
Pain. 2023 Nov 28. doi: 10.1097/j.pain.0000000000003104.
PubMed Abstract available

SOLE E, Roman-Juan J, Sanchez-Rodriguez E, Castarlenas E, et al
School bullying and peer relationships in children with chronic pain.
Pain. 2023 Nov 28. doi: 10.1097/j.pain.0000000000003118.
PubMed Abstract available

SMITH BH, Belton JL
Patient engagement in pain research: no gain without the people in pain.
Pain. 2023 Nov 28. doi: 10.1097/j.pain.0000000000003122.
PubMed

CLEMENS KS, Vang M, Colloca L, Sieg M, et al
The desire for side-effect information in pain treatment: an experimental analysis of contextual and individual difference factors.
Pain. 2023 Nov 16. doi: 10.1097/j.pain.0000000000003025.
PubMed Abstract available

GOODE DJ
Immunotherapy, a new approach for the treatment of human pain.
Pain. 2023 Nov 16. doi: 10.1097/j.pain.0000000000003107.
PubMed

LIU PW, Zhang H, Werley CA, Pichler M, et al
A phenotypic screening platform for chronic pain therapeutics using all-optical electrophysiology.
Pain. 2023 Nov 14. doi: 10.1097/j.pain.0000000000003090.
PubMed Abstract available

O'BRIEN JA, Karrasch JF, Huang Y, Vine EE, et al
Nerve-myeloid cell interactions in persistent human pain: a reappraisal using updated cell subset classifications.
Pain. 2023 Nov 14. doi: 10.1097/j.pain.0000000000003106.
PubMed Abstract available

ZHANG H, Zhao L, Lu X, Peng W, et al
Multimodal covarying brain patterns mediate genetic and psychological contributions to individual differences in pain sensitivity.
Pain. 2023 Nov 9. doi: 10.1097/j.pain.0000000000003103.
PubMed Abstract available

REZZONICO JOST T, Lozito A, Mangani D, Raimondi A, et al
CD304+ adipose tissue-derived mesenchymal stem cell abundance in autologous fat grafts highly correlates with improvement of localized pain syndromes.
Pain. 2023 Nov 9. doi: 10.1097/j.pain.0000000000003092.
PubMed Abstract available

BERGMANS RS, Clauw DJ, Flint C, Harris H, et al
Chronic overlapping pain conditions increase the risk of long COVID features, regardless of acute COVID status.
Pain. 2023 Nov 9. doi: 10.1097/j.pain.0000000000003110.
PubMed Abstract available

LIU SS, Pickens S, Barta Z, Rice M, et al
Neuroinflammation drives sex-dependent effects on pain and negative affect in a murine model of repeated mild traumatic brain injury.
Pain. 2023 Nov 8. doi: 10.1097/j.pain.0000000000003084.
PubMed Abstract available

SOMMER C, Calvo M, Cervero F, Loeser JD, et al
Future perspectives: the next fifty years of the International Association for the Study of Pain.
Pain. 2023;164.
PubMed Abstract available

SOYANNWO O, Chaudakshetrin P, Garcia JB
The value of the International Association for the Study of Pain to developing countries.
Pain. 2023;164.
PubMed Abstract available

SHARMA S, Birnie KA, Wang S, Fernandes Gomes FI, et al
The value of the International Association for the Study of Pain to career development: perspectives of trainee and early career members.
Pain. 2023;164.
PubMed Abstract available

DAVIS KD, Basbaum AI, Bushnell MC, Yarnitsky D, et al
International Association for the Study of Pain publications over the 50-year span.
Pain. 2023;164.
PubMed Abstract available

ARENDT NIELSEN L, Belton J, Cardosa M
Beyond the study of pain: the evolving role of the International Association for the Study of Pain in global advocacy.
Pain. 2023;164.
PubMed Abstract available

FLOR H, Noguchi K, Treede RD, Turk DC, et al
The role of evolving concepts and new technologies and approaches in advancing pain research, management, and education since the establishment of the International Association for the Study of Pain.
Pain. 2023;164.
PubMed Abstract available

BASBAUM AI, Jensen TS, Keefe FJ
Fifty years of pain research and clinical advances: highlights and key trends.
Pain. 2023;164.
PubMed Abstract available

NICHOLAS MK, Cardosa M, Turner J
Educational initiatives and achievements of the International Association for the Study of Pain.
Pain. 2023;164.
PubMed Abstract available

SESSLE BJ
Introduction and a brief historical overview of the International Association for the Study of Pain.
Pain. 2023;164.
PubMed Abstract available

DAVIS KD, Sessle BJ
A PAIN supplement commemorating the 50th anniversary of the International Association for the Study of Pain.
Pain. 2023;164.
PubMed

Message from the president of the International Association for the Study of Pain.
Pain. 2023;164.
PubMed

October 2023

ERDOGAN O, Michot B, Xia J, Alabdulaaly L, et al
Neuronal-immune axis alters pain and sensory afferent damage during dental pulp injury.
Pain. 2023 Oct 30. doi: 10.1097/j.pain.0000000000003029.
PubMed Abstract available

DOSHI TL, Sandbrink F, Cohen SP
Postamputation limb pain in military personnel: separate but equal or separate and never equal?
Pain. 2023 Oct 30. doi: 10.1097/j.pain.0000000000003095.
PubMed

HAN S, Ren J, Li Z, Wen J, et al
Deactivation of dorsal CA1 pyramidal neurons projecting to medial prefrontal cortex contributes to neuropathic pain and short-term memory impairment.
Pain. 2023 Oct 27. doi: 10.1097/j.pain.0000000000003100.
PubMed Abstract available

BOYSE JB, Sharpe L, Richmond B, Dear B, et al
Benign or painful? The interpretation of pain and fear of progression in rheumatoid arthritis.
Pain. 2023 Oct 26. doi: 10.1097/j.pain.0000000000003081.
PubMed Abstract available

NEUGEBAUER V, Kiritoshi T
Corticolimbic plasticity in pain: hippocampus joins the party.
Pain. 2023 Oct 26. doi: 10.1097/j.pain.0000000000003101.
PubMed

BEKAURI T, Fischer S, Honn KV, Maddipati KR, et al
Inflammation, lipid dysregulation, and transient receptor potential cation channel subfamily V member 4 signaling perpetuate chronic vulvar pain.
Pain. 2023 Oct 26. doi: 10.1097/j.pain.0000000000003088.
PubMed Abstract available

MAZAHERI A, Furman AJ, Seminowicz DA
Fear and pain slow the brain.
Pain. 2023 Oct 26. doi: 10.1097/j.pain.0000000000003099.
PubMed

ALBERTS NM, Gilbert A, Kang G, Okhomina VI, et al
Agreement between youth and caregiver report of pain and functioning in pediatric sickle cell disease: PedsQL sickle cell disease module.
Pain. 2023 Oct 25. doi: 10.1097/j.pain.0000000000003079.
PubMed Abstract available

SOENS MA, Sesso HD, Manson JE, Fields KG, et al
The effect of vitamin D and omega-3 fatty acid supplementation on pain prevalence and severity in older adults: a large-scale ancillary study of the VITamin D and OmegA-3 triaL (VITAL).
Pain. 2023 Oct 25. doi: 10.1097/j.pain.0000000000003044.
PubMed Abstract available

TESARZ J, Herpel C, Meischner M, Drusko A, et al
Effects of virtual reality on psychophysical measures of pain: superiority to imagination and nonimmersive conditions.
Pain. 2023 Oct 25. doi: 10.1097/j.pain.0000000000003083.
PubMed Abstract available

MIKKELSEN MB, Neumann H, Buskbjerg CR, Johannsen M, et al
The effect of experimental emotion induction on experimental pain: a systematic review and meta-analysis.
Pain. 2023 Oct 25. doi: 10.1097/j.pain.0000000000003073.
PubMed Abstract available

NOYEK S, Jessa JS, Faulkner V, Boerner KE, et al
A systematic review of self and observer assessment of pain and related functioning in youth with brain-based developmental disabilities.
Pain. 2023 Oct 23. doi: 10.1097/j.pain.0000000000003066.
PubMed Abstract available

LASCURAIN-AGUIRREBENA I, Dominguez L, Villanueva-Ruiz I, Ballesteros J, et al
Effectiveness of neural mobilisation for the treatment of nerve-related cervicobrachial pain: a systematic review with subgroup meta-analysis.
Pain. 2023 Oct 23. doi: 10.1097/j.pain.0000000000003071.
PubMed Abstract available

GOMEZ K, Allen HN, Duran P, Loya-Lopez S, et al
Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain.
Pain. 2023 Oct 20. doi: 10.1097/j.pain.0000000000003080.
PubMed Abstract available

MANDONNET V, Obaid S, Descoteaux M, St-Onge E, et al
Electrostimulation of the white matter of the posterior insula and medial operculum: perception of vibrations, heat, and pain.
Pain. 2023 Oct 20. doi: 10.1097/j.pain.0000000000003069.
PubMed Abstract available

NIEDERER D, Schiller J, Groneberg DA, Behringer M, et al
Machine learning-based identification of determinants for rehabilitation success and future healthcare use prevention in patients with high-grade, chronic, nonspecific low back pain: an individual data 7-year follow-up analysis on 154,167 individuals.
Pain. 2023 Oct 19. doi: 10.1097/j.pain.0000000000003087.
PubMed Abstract available

SCHONNAGEL L, Muellner M, Suwalski P, Guven AE, et al
Association of abdominal aortic calcification and lower back pain in patients with degenerative spondylolisthesis.
Pain. 2023 Oct 19. doi: 10.1097/j.pain.0000000000003018.
PubMed Abstract available

SALOMONS TV, Moayedi M
How should we measure the relationship between pain and interoception?
Pain. 2023 Oct 19. doi: 10.1097/j.pain.0000000000003033.
PubMed

CHEN L, Jiang J, Dou B, Feng H, et al
Machine learning study of the extended drug-target interaction network informed by pain related voltage-gated sodium channels.
Pain. 2023 Oct 18. doi: 10.1097/j.pain.0000000000003089.
PubMed Abstract available

STIJIC M, Messerer B, Meissner W, Avian A, et al
Numeric rating scale for pain should be used in an ordinal but not interval manner. A retrospective analysis of 346,892 patient reports of the quality improvement in postoperative pain treatment registry.
Pain. 2023 Oct 18. doi: 10.1097/j.pain.0000000000003078.
PubMed Abstract available

BOUHASSIRA D, Tesfaye S, Sarkar A, Soisalon-Soininen S, et al
Efficacy and safety of eliapixant in diabetic neuropathic pain and prediction of placebo responders with an exploratory novel algorithm: results from the randomized controlled phase 2a PUCCINI study.
Pain. 2023 Oct 18. doi: 10.1097/j.pain.0000000000003085.
PubMed Abstract available

BOUHASSIRA D, Jazat-Poindessous F, Farnes N, Franchisseur C, et al
Comparison of the analgesic effects of "superficial" and "deep" repetitive transcranial magnetic stimulation in patients with central neuropathic pain: a randomized sham-controlled multicenter international crossover study.
Pain. 2023 Oct 18. doi: 10.1097/j.pain.0000000000003082.
PubMed Abstract available

VAN DER MIESEN MM, Joosten EA, Kaas AL, Linden DEJ, et al
Habituation to pain: self-report, electroencephalography, and functional magnetic resonance imaging in healthy individuals. A scoping review and future recommendations.
Pain. 2023 Oct 17. doi: 10.1097/j.pain.0000000000003052.
PubMed Abstract available

MOORE DJ
Commentary on: A systematic review of self and observer assessment of pain and related functioning in youth with brain-based developmental disabilities.
Pain. 2023 Oct 17. doi: 10.1097/j.pain.0000000000003067.
PubMed

TARGOWSKA-DUDA KM, Peters D, Marcus JL, Zribi G, et al
Functional and anatomical analyses of active spinal circuits in a mouse model of chronic pain.
Pain. 2023 Oct 10. doi: 10.1097/j.pain.0000000000003068.
PubMed Abstract available

GODBOUT-PARENT M, Julien N, Nguena Nguefack HL, Page MG, et al
Changing society, changing research: integrating gender to better understand physical and psychological treatments use in chronic pain management.
Pain. 2023 Oct 9. doi: 10.1097/j.pain.0000000000003072.
PubMed Abstract available

Fibromyalgia predicts increased odds of pain-related addiction exacerbation among individuals with pain and opioid use disorder: erratum.
Pain. 2023;164:2382.
PubMed

ALI S
Practical nonpharmacologic pain interventions for hospitalized cancer patients.
Pain. 2023;164:2380.
PubMed

September 2023

OLIVEIRA I, Vaz Garrido M, Carvalho H, Figueira Bernardes S, et al
Sensing the body matters: profiles of interoceptive sensibility in chronic pain adjustment.
Pain. 2023 Sep 27. doi: 10.1097/j.pain.0000000000003032.
PubMed Abstract available

GERVASON S, Meleine M, Lolignier S, Meynier M, et al
Antihyperalgesic properties of gut microbiota: Parabacteroides distasonis as a new probiotic strategy to alleviate chronic abdominal pain.
Pain. 2023 Sep 27. doi: 10.1097/j.pain.0000000000003075.
PubMed Abstract available

DA SILVA JT, Hernandez-Rojas LG, Mekonen HK, Hanson S, et al
Sex differences in visceral sensitivity and brain activity in a rat model of comorbid pain: a longitudinal study.
Pain. 2023 Sep 27. doi: 10.1097/j.pain.0000000000003074.
PubMed Abstract available

GARCIA-LARREA L
Under the insula: a commentary on "electrostimulation of the white matter of the posterior insula and medial operculum: perception of vibrations, heat, and pain".
Pain. 2023 Sep 27. doi: 10.1097/j.pain.0000000000003070.
PubMed

ESPIRITO SANTO CM, Santos VS, Kamper SJ, Williams CM, et al
Overview of the economic burden of musculoskeletal pain in children and adolescents: a systematic review with meta-analysis.
Pain. 2023 Sep 26. doi: 10.1097/j.pain.0000000000003037.
PubMed Abstract available

LOYA-LOPEZ SI, Allen HN, Duran P, Calderon-Rivera A, et al
Intranasal CRMP2-Ubc9 inhibitor regulates NaV1.7 to alleviate trigeminal neuropathic pain.
Pain. 2023 Sep 26. doi: 10.1097/j.pain.0000000000003053.
PubMed Abstract available

MATTHIAS MS, Daggy JK, Perkins AJ, Adams J, et al
Communication and activation in pain to enhance relationships and treat pain with equity (COOPERATE): a randomized clinical trial.
Pain. 2023 Sep 21. doi: 10.1097/j.pain.0000000000003021.
PubMed Abstract available

NEGM A, Stobbe K, Ben Fradj S, Sanchez C, et al
Acid-sensing ion channel 3 mediates pain hypersensitivity associated with high-fat diet consumption in mice.
Pain. 2023 Sep 21. doi: 10.1097/j.pain.0000000000003030.
PubMed Abstract available

PALERMO TM, Lalloo C, Zhou C, Dampier C, et al
A cognitive-behavioral digital health intervention for sickle cell disease pain in adolescents: a randomized, controlled, multicenter trial.
Pain. 2023 Sep 21. doi: 10.1097/j.pain.0000000000003009.
PubMed Abstract available

KASHYAP Y, Wang ZJ
Gut microbiota dysbiosis alters chronic pain behaviors in a humanized transgenic mouse model of sickle cell disease.
Pain. 2023 Sep 21. doi: 10.1097/j.pain.0000000000003034.
PubMed Abstract available

DE LA ROSA JS, Brady BR, Ibrahim MM, Herder KE, et al
Co-occurrence of chronic pain and anxiety/depression symptoms in U.S. adults: prevalence, functional impacts, and opportunities.
Pain. 2023 Sep 21. doi: 10.1097/j.pain.0000000000003056.
PubMed Abstract available

PAVY F, Zaman J, Von Leupoldt A, Torta DM, et al
Expectations underlie the effects of unpredictable pain: a behavioral and electroencephalogram study.
Pain. 2023 Sep 13. doi: 10.1097/j.pain.0000000000003046.
PubMed Abstract available

POGATZKI-ZAHN EM, Segelcke D
Searching for the rainbow: biomarkers relevant for chronic postsurgical pain.
Pain. 2023 Sep 13. doi: 10.1097/j.pain.0000000000003043.
PubMed

WIECH K, Bingel U
Alzheimer disease may compromise patients' ability for expectancy-based pain modulation. Now what?
Pain. 2023 Sep 13. doi: 10.1097/j.pain.0000000000003036.
PubMed

OPDENSTEINEN KD, Rach H, Gruszka P, Schaan L, et al
"The mere imagination scares me"-evidence for fear responses during mental imagery of pain-associated interoceptive sensations in adolescents with chronic pain.
Pain. 2023 Sep 8. doi: 10.1097/j.pain.0000000000003041.
PubMed Abstract available

GILRON I, Robb S, Tu D, Holden RR, et al
Randomized, double-blind, controlled trial of a combination of alpha-lipoic acid and pregabalin for neuropathic pain: the PAIN-CARE trial.
Pain. 2023 Sep 7. doi: 10.1097/j.pain.0000000000003038.
PubMed Abstract available

INYANG KE, Evans CM, Heussner M, Petroff M, et al
HPV+ head and neck cancer-derived small extracellular vesicles communicate with TRPV1+ neurons to mediate cancer pain.
Pain. 2023 Sep 6. doi: 10.1097/j.pain.0000000000003045.
PubMed Abstract available

OJALA J, Suvilehto JT, Nummenmaa L, Kalso E, et al
Bodily maps of emotions and pain: tactile and hedonic sensitivity in healthy controls and patients experiencing chronic pain.
Pain. 2023 Sep 6. doi: 10.1097/j.pain.0000000000003027.
PubMed Abstract available

GIORDANO R, Ghafouri B, Arendt-Nielsen L, Petersen KK, et al
Inflammatory biomarkers in patients with painful knee osteoarthritis: exploring the potential link to chronic postoperative pain after total knee arthroplasty-a secondary analysis.
Pain. 2023 Sep 6. doi: 10.1097/j.pain.0000000000003042.
PubMed Abstract available

GREEN CR
Improving the art and science of communication in people living with chronic pain.
Pain. 2023 Sep 6. doi: 10.1097/j.pain.0000000000003022.
PubMed

ANTUNES FTT, Zamponi GW
UnCRMPing Nav1.7 to treat trigeminal neuropathic pain.
Pain. 2023 Sep 6. doi: 10.1097/j.pain.0000000000003054.
PubMed

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