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Articles published in Antimicrob Agents Chemother

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    July 2021
  1. VAN LOON W, Bergmann C, Habarugira F, Tacoli C, et al
    Changing pattern of Plasmodium falciparum multi-drug resistance-1 gene polymorphisms in southern Rwanda.
    Antimicrob Agents Chemother. 2021 Jul 6:AAC0090121. doi: 10.1128/AAC.00901.
    PubMed     Abstract available


    June 2021
  2. TAN S, Mudeppa DG, Kokkonda S, White J 3rd, et al
    Properties of Plasmodium falciparum with a deleted apicoplast DNA gyrase.
    Antimicrob Agents Chemother. 2021 Jun 21:AAC0058621. doi: 10.1128/AAC.00586.
    PubMed     Abstract available


  3. TABASSUM W, Singh P, Suthram N, Bhattacharyya S, et al
    Elevated DNA damage sensitivity in malaria parasite induced by the synergistic action between PfHsp90 inhibitor and PfRad51 inhibitor.
    Antimicrob Agents Chemother. 2021 Jun 7:AAC0045721. doi: 10.1128/AAC.00457.
    PubMed     Abstract available


  4. BESHIR KB, Diallo N, Some FA, Sombie S, et al
    Persistent sub-microscopic Plasmodium falciparum parasitaemia 72 hours after treatment with artemether-lumefantrine predicts 42-day treatment failure in Mali and Burkina Faso.
    Antimicrob Agents Chemother. 2021 Jun 1:AAC0087321. doi: 10.1128/AAC.00873.
    PubMed     Abstract available


    April 2021
  5. GOMES-ALVES AG, Duarte M, Cruz T, Castro H, et al
    Quinolin-(1H)-imines as a new chemotype against leishmaniasis: biological evaluation and mechanistic studies.
    Antimicrob Agents Chemother. 2021 Apr 26. pii: AAC.01513.
    PubMed     Abstract available


  6. FENG J, Xu D, Kong X, Lin K, et al
    Characterization of pfmdr1, pfcrt, pfK13, pfubp1, and pfap2mu in travelers returning from Africa with Plasmodium falciparum infections reported in China from 2014-2018.
    Antimicrob Agents Chemother. 2021 Apr 26. pii: AAC.02717.
    PubMed     Abstract available


  7. DICKIE EA, Ronin C, Sa M, Ciesielski F, et al
    Towards chemical validation of Leishmania infantum ribose 5-phosphate isomerase as a drug target.
    Antimicrob Agents Chemother. 2021 Apr 19. pii: AAC.01892.
    PubMed     Abstract available


  8. PERNAUTE-LAU L, Adegnika AA, Zhou Y, Zinsou JF, et al
    Pharmacogene sequencing of a Gabonese population with severe Plasmodium falciparum malaria reveals multiple novel variants with putative relevance for antimalarial treatment.
    Antimicrob Agents Chemother. 2021 Apr 19. pii: AAC.00275.
    PubMed     Abstract available


    March 2021
  9. BURGERT L, Zaloumis S, Dini S, Marquart L, et al
    Parasite-Host Dynamics throughout Antimalarial Drug Development Stages Complicate the Translation of Parasite Clearance.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  10. CAO Y, Sun C, Wen H, Wang M, et al
    A yeast-based drug discovery platform to identify Plasmodium falciparum type II NADH dehydrogenase inhibitors.
    Antimicrob Agents Chemother. 2021 Mar 15. pii: AAC.02470.
    PubMed     Abstract available


  11. SI Y, Zeng W, Li N, Wang C, et al
    In Vitro Susceptibility of Plasmodium falciparum Isolates from the China-Myanmar Border Area to Piperaquine and Association with Candidate Markers.
    Antimicrob Agents Chemother. 2021 Mar 8. pii: AAC.02305.
    PubMed     Abstract available


  12. CHAN CF, Liu Z, Wong ILK, Zhao X, et al
    Amine-Linked Flavonoids as Agents Against Cutaneous Leishmaniasis.
    Antimicrob Agents Chemother. 2021 Mar 8. pii: AAC.02165.
    PubMed     Abstract available


  13. ZALOUMIS SG, Whyte JM, Tarning J, Krishna S, et al
    Development and validation of an in silico decision-tool to guide optimisation of intravenous artesunate dosing regimens for severe falciparum malaria patients.
    Antimicrob Agents Chemother. 2021 Mar 8. pii: AAC.02346.
    PubMed     Abstract available


  14. MARIN AA, Murillo O, Sussmann RA, Ortolan LS, et al
    Perillyl alcohol reduces parasite sequestration and cerebrovascular dysfunction during experimental cerebral malaria.
    Antimicrob Agents Chemother. 2021 Mar 1. pii: AAC.00004.
    PubMed     Abstract available


    February 2021
  15. ANDRADE-NETO VV, Rebello KM, Pereira TM, Torres-Santos EC, et al
    Effect of Itraconazole-Ezetimibe-Miltefosine Ternary Therapy in Murine Visceral Leishmaniasis.
    Antimicrob Agents Chemother. 2021 Feb 22. pii: AAC.02676.
    PubMed     Abstract available


  16. LI H, Abraham A, Gazzola D, Hu Y, et al
    Recombinant Paraprobiotics as a New Paradigm for Treating Gastrointestinal Nematode Parasites of Humans.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  17. QUANG HH, Chavchich M, Trinh NTM, Edgel KA, et al
    Multidrug-resistant Plasmodium falciparum parasites in the Central Highlands of Vietnam jeopardize malaria control and elimination strategies.
    Antimicrob Agents Chemother. 2021 Feb 1. pii: AAC.01639.
    PubMed     Abstract available


    January 2021
  18. RIBBISO KA, Heller LE, Taye A, Julian E, et al
    Artemisinin - Based Drugs Target the Plasmodium falciparum heme-detoxification pathway.
    Antimicrob Agents Chemother. 2021 Jan 25. pii: AAC.02137.
    PubMed     Abstract available


  19. TEWARI SG, Rajaram K, Swift RP, Reifman J, et al
    Metabolic survival adaptations of Plasmodium falciparum exposed to sub-lethal doses of fosmidomycin.
    Antimicrob Agents Chemother. 2021 Jan 25. pii: AAC.02392.
    PubMed     Abstract available


  20. WATTANAKUL T, Baker M, Mohrle J, McWhinney B, et al
    Semi-mechanistic pharmacokinetic and pharmacodynamic modelling of piperaquine in a volunteer infection study with Plasmodium falciparum blood-stage malaria.
    Antimicrob Agents Chemother. 2021 Jan 19. pii: AAC.01583.
    PubMed     Abstract available


    December 2020
  21. PAINTER HJ, Morrisey JM, Mather MW, Orchard LM, et al
    Atypical molecular basis for drug resistance to mitochondrial function inhibitors in Plasmodium falciparum.
    Antimicrob Agents Chemother. 2020 Dec 23. pii: AAC.02143.
    PubMed     Abstract available


  22. XU L, Liu Q, Zeng Q, Wu P, et al
    Radicicol, a Novel Lead Compound Against the Migratory-stage Schistosomula of Schistosoma japonicum.
    Antimicrob Agents Chemother. 2020 Dec 23. pii: AAC.01781.
    PubMed     Abstract available


  23. LIN JT, Waltmann A, Moser KA, Park Z, et al
    Selection of cytochrome b mutants is rare among Plasmodium falciparum patients failing treatment with atovaquone-proguanil in Cambodia.
    Antimicrob Agents Chemother. 2020 Dec 23. pii: AAC.01249.
    PubMed     Abstract available


    November 2020
  24. DEBBERT SL, Hintz MJ, Bell CJ, Earl KR, et al
    Activities of Quinoxaline, Nitroquinoxaline and [1,2,4]Triazolo[4,3-a]quinoxaline Analogs of MMV007204 against Schistosoma mansoni.
    Antimicrob Agents Chemother. 2020 Nov 30. pii: AAC.01370.
    PubMed     Abstract available


  25. MCCARTHY JS, Abd-Rahman AN, Collins KA, Marquart L, et al
    Defining the antimalarial activity of cipargamin in healthy volunteers experimentally infected with blood stage Plasmodium falciparum.
    Antimicrob Agents Chemother. 2020 Nov 16. pii: AAC.01423.
    PubMed     Abstract available


  26. WITMER K, Dahalan FA, Delves MJ, Yahiya S, et al
    Transmission of artemisinin-resistant malaria parasites to mosquitoes under antimalarial drug pressure.
    Antimicrob Agents Chemother. 2020 Nov 2. pii: AAC.00898.
    PubMed     Abstract available


    October 2020
  27. FERREIRA LT, Rodrigues J, Cassiano GC, Tavella TA, et al
    Correction for Ferreira et al., "Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax".
    Antimicrob Agents Chemother. 2020;64.
    PubMed    


  28. SEN U, Nayak A, Khurana J, Sharma D, et al
    Inhibition of PfMYST HAT activity blocks Plasmodium falciparum growth and survival.
    Antimicrob Agents Chemother. 2020 Oct 12. pii: AAC.00953.
    PubMed     Abstract available


  29. ETXEBESTE-MITXELTORENA M, Plano D, Espuelas S, Moreno E, et al
    New amides containing selenium as potent leishmanicidal agents targeting trypanothione reductase.
    Antimicrob Agents Chemother. 2020 Oct 12. pii: AAC.00524.
    PubMed     Abstract available


  30. MBYE H, Bojang F, Jawara AS, Njie B, et al
    Tolerance of Gambian Plasmodium falciparum to Dihydroartemisinin and Lumefantrine detected by Ex vivo Parasite Survival Rate Assay (PSRA).
    Antimicrob Agents Chemother. 2020 Oct 5. pii: AAC.00720.
    PubMed     Abstract available


  31. NAYEBARE P, Asua V, Conrad MD, Kajubi R, et al
    Associations between malaria preventive regimens and Plasmodium falciparum drug resistance mediating polymorphisms in Ugandan pregnant women.
    Antimicrob Agents Chemother. 2020 Oct 5. pii: AAC.01047.
    PubMed     Abstract available


    September 2020
  32. DE MORAES ALVES MM, Arcanjo DDR, Figueiredo KA, Oliveira JSSM, et al
    Gallic and Ellagic acids: Promising adjuvants to conventional amphotericin B for the treatment of cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2020 Sep 14. pii: AAC.00807.
    PubMed     Abstract available


  33. SANTOS CC, Zhang H, Batista MM, de Oliveira GM, et al
    In vitro and in vivo evaluation of an adamantyl-based phenyl sulfonyl acetamide against cutaneous leishmaniasis models of L. amazonensis.
    Antimicrob Agents Chemother. 2020 Sep 14. pii: AAC.01188.
    PubMed     Abstract available


    August 2020
  34. YAN H, Kong X, Zhang T, Xiao H, et al
    Prevalence of Plasmodium falciparum Kelch 13 (PfK13) and ubiquitin-specific protease 1 (pfubp1) gene polymorphisms in returning travellers from Africa reported in Eastern China.
    Antimicrob Agents Chemother. 2020 Aug 24. pii: AAC.00981.
    PubMed     Abstract available


  35. DE BRITO MG, Mengarda AC, Oliveira GL, Cirino ME, et al
    Therapeutic effect of diminazene aceturate on parasitic blood fluke Schistosoma mansoni infection.
    Antimicrob Agents Chemother. 2020 Aug 17. pii: AAC.01372.
    PubMed     Abstract available


    July 2020
  36. CUU G, Asua V, Tukwasibwe S, Nsobya S, et al
    Associations between aminoquinoline resistance genotypes and clinical presentations of Plasmodium falciparum infection in Uganda.
    Antimicrob Agents Chemother. 2020 Jul 13. pii: AAC.00721.
    PubMed     Abstract available


  37. BUSTINDUY AL, Kolamunnage-Dona R, Mirochnick MH, Capparelli EV, et al
    Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women infected with Schistosoma japonicum.
    Antimicrob Agents Chemother. 2020 Jul 6. pii: AAC.00566.
    PubMed     Abstract available


    June 2020
  38. FERREIRA LT, Rodrigues J, Cassiano GC, Tavella TA, et al
    Computational chemogenomics drug repositioning strategy enables the discovery of Epirubicin as a new repurposed hit for P. falciparum and P. vivax.
    Antimicrob Agents Chemother. 2020 Jun 29. pii: AAC.02041.
    PubMed     Abstract available


  39. ALVAREZ MG, Ramirez JC, Bertocchi G, Fernandez M, et al
    New scheme of intermittent benznidazole administration in patients chronically infected with Trypanosoma cruzi: Clinical, parasitological and serological assessment after three years of follow-up.
    Antimicrob Agents Chemother. 2020 Jun 22. pii: AAC.00439.
    PubMed     Abstract available


    May 2020
  40. YADAV S, Kuldeep J, Siddiqi MI, Goyal N, et al
    TCP1gamma subunit is indispensable for growth and infectivity of Leishmania donovani.
    Antimicrob Agents Chemother. 2020 May 26. pii: AAC.00669.
    PubMed     Abstract available


  41. FEHLING H, Choy SL, Ting F, Landschulze D, et al
    Anti-leishmanial effects of synthetic EhPIb analogs derived from the Entamoeba histolytica lipopeptidephosphoglycan.
    Antimicrob Agents Chemother. 2020 May 11. pii: AAC.00161.
    PubMed     Abstract available


  42. KASHIF M, Paladhi A, Singh R, Bhattacharyya S, et al
    Evaluation of leishmanicidal activity of an in silico screened novel inhibitor against ascorbate peroxidase of Leishmania donovani.
    Antimicrob Agents Chemother. 2020 May 4. pii: AAC.01766.
    PubMed     Abstract available


  43. VANHEER LN, Zhang H, Lin G, Kafsack BFC, et al
    Activity of epigenetic inhibitors against Plasmodium falciparum asexual and sexual blood stages.
    Antimicrob Agents Chemother. 2020 May 4. pii: AAC.02523.
    PubMed     Abstract available


    April 2020
  44. WATTANAKUL T, Ogutu B, Kabanywanyi AM, Asante KP, et al
    Cardiovascular safety and population pharmacokinetic properties of piperaquine in African patients with uncomplicated falciparum malaria - a pooled multicentre analysis.
    Antimicrob Agents Chemother. 2020 Apr 20. pii: AAC.01848.
    PubMed     Abstract available


  45. DOS SANTOS CCP, Ramos GS, De Paula RC, Faria KF, et al
    Therapeutic efficacy of a mixed formulation of conventional and PEGylated liposomes containing meglumine antimoniate, combined with allopurinol, in dogs naturally infected with Leishmania infantum.
    Antimicrob Agents Chemother. 2020 Apr 13. pii: AAC.00234.
    PubMed     Abstract available


    March 2020
  46. VANTAUX A, Kim S, Piv E, Chy S, et al
    Significant efficacy of single low dose primaquine compared to stand alone artemisinin combination therapy in reducing gametocyte carriage in Cambodian patients with uncomplicated multidrug resistant Plasmodium falciparum malaria.
    Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02108.
    PubMed     Abstract available


  47. CHAN A, Dziedziech A, Kirkman LA, Deitsch KW, et al
    A histone methyltransferase inhibitor can reverse epigenetically acquired drug resistance in the malaria parasite Plasmodium falciparum.
    Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02021.
    PubMed     Abstract available


    February 2020
  48. PATRA AT, Hingmire TB, Belekar M, Xiong A, et al
    Whole Cell Phenotypic Screening Of MMV Pathogen Box identifies Specific Inhibitors of Plasmodium falciparum late-stage development and egress.
    Antimicrob Agents Chemother. 2020 Feb 18. pii: AAC.01802.
    PubMed     Abstract available


  49. ROTTMANN M, Jonat B, Gumpp C, Dhingra SK, et al
    Preclinical Antimalarial Combination Studies: The Case of M5717, a P. falciparum Elongation Factor 2 Inhibitor and Pyronaridine, a Hemozoin Formation Inhibitor.
    Antimicrob Agents Chemother. 2020 Feb 10. pii: AAC.02181.
    PubMed     Abstract available


    January 2020
  50. MENSAH BA, Aydemir O, Myers-Hansen JL, Opoku M, et al
    Antimalarial drug resistance profiling of Plasmodium falciparum infections in Ghana using molecular inversion probes and next generation sequencing.
    Antimicrob Agents Chemother. 2020 Jan 13. pii: AAC.01423.
    PubMed     Abstract available


  51. URSING J, Rombo L, Eksborg S, Larson L, et al
    High-dose chloroquine for uncomplicated Plasmodium falciparum malaria is well tolerated and causes similar QT prolongation as standard dose chloroquine in children.
    Antimicrob Agents Chemother. 2020 Jan 6. pii: AAC.01846.
    PubMed     Abstract available


    December 2019
  52. RIEZK A, Raynes JG, Yardley V, Murdan S, et al
    Activity of chitosan and its derivatives against Leishmania major and L. mexicana in vitro.
    Antimicrob Agents Chemother. 2019 Dec 23. pii: AAC.01772.
    PubMed     Abstract available


  53. VIEIRA JLF, Rivera JGB, de Sena LWP, Ferreira MVD, et al
    Association of lipid levels with mefloquine and carboxy-mefloquine concentrations in patients with uncomplicated falciparum malaria.
    Antimicrob Agents Chemother. 2019 Dec 16. pii: AAC.01731.
    PubMed     Abstract available


  54. ONYAMBOKO MA, Hoglund RM, Lee SJ, Kabedi C, et al
    A randomised controlled trial of 3 versus 5 days artemether-lumefantrine regimen for uncomplicated Plasmodium falciparum treatment in pregnancy in Africa.
    Antimicrob Agents Chemother. 2019 Dec 9. pii: AAC.01140.
    PubMed     Abstract available


    November 2019
  55. MCCARTHY JS, Ruckle T, Elliott SL, Ballard E, et al
    A single dose combination study with the experimental antimalarials artefenomel and DSM265 to determine safety and antimalarial activity against blood-stage Plasmodium falciparum in healthy volunteers.
    Antimicrob Agents Chemother. 2019 Nov 4. pii: AAC.01371.
    PubMed     Abstract available


    October 2019
  56. SHAW CD, Imamura H, Downing T, Blackburn G, et al
    Genomic and metabolomic polymorphism among experimentally selected paromomycin-resistant Leishmania donovani strains.
    Antimicrob Agents Chemother. 2019 Oct 28. pii: AAC.00904.
    PubMed     Abstract available


  57. HENRICI RC, van Schalkwyk DA, Sutherland CJ
    Modification of pfap2mu and pfubp1 markedly reduces ring-stage susceptibility of Plasmodium falciparum to artemisinin in vitro.
    Antimicrob Agents Chemother. 2019 Oct 21. pii: AAC.01542.
    PubMed     Abstract available


  58. WAMAE K, Okanda D, Ndwiga L, Osoti V, et al
    No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type parasites.
    Antimicrob Agents Chemother. 2019 Oct 7. pii: AAC.01067.
    PubMed     Abstract available


    September 2019
  59. ROQUINI DB, Cogo RM, Mengarda AC, Mazloum SF, et al
    Promethazine exhibits antiparasitic properties in vitro and reduces worm burden, egg production, hepato-, and splenomegaly in a schistosomiasis animal model.
    Antimicrob Agents Chemother. 2019 Sep 16. pii: AAC.01208.
    PubMed     Abstract available


    August 2019
  60. CATON E, Nenortas E, Bakshi RP, Shapiro TA, et al
    Kinetic Driver of Antibacterial Drugs Against Plasmodium falciparum: Implications for Clinical Dosing.
    Antimicrob Agents Chemother. 2019 Aug 26. pii: AAC.00416.
    PubMed     Abstract available


  61. MATREVI SA, Opoku-Agyeman P, Quashie NB, Bruku S, et al
    Plasmodium falciparum kelch propeller polymorphisms in clinical isolates from Ghana: 2007-2016.
    Antimicrob Agents Chemother. 2019 Aug 19. pii: AAC.00802.
    PubMed     Abstract available


  62. PETT H, Bradley J, Okebe J, Dicko A, et al
    CYP2D6 polymorphisms and the safety and gametocytocidal activity of single dose primaquine for P. falciparum.
    Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.00538.
    PubMed     Abstract available


    July 2019
  63. ZHOU R, Yang C, Li S, Zhao Y, et al
    Molecular surveillance of drug resistance of Plasmodium falciparum isolates imported from Angola in Henan Province, China.
    Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.00552.
    PubMed     Abstract available


  64. CONRAD MD, Nsobya SL, Rosenthal PJ
    The diversity of the Plasmodium falciparum K13 propeller domain did not increase after implementation of artemisinin-based combination therapy in Uganda.
    Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.01234.
    PubMed     Abstract available


  65. EGUI A, Thomas MC, Fernandez-Villegas A, Perez-Anton E, et al
    A parasite biomarker set for evaluating benznidazole treatment efficacy in patients with chronic asymptomatic Trypanosoma cruzi infection.
    Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.02436.
    PubMed     Abstract available


  66. CHAKRABARTI R, White J, Babar PH, Kumar S, et al
    Decreased in vitro artemisinin sensitivity of Plasmodium falciparum across India.
    Antimicrob Agents Chemother. 2019 Jul 22. pii: AAC.00101.
    PubMed     Abstract available


  67. WIJNANT GJ, Croft SL, de la Flor R, Alavijeh M, et al
    Pharmacokinetics and pharmacodynamics of the nitroimidazole DNDI-0690 in mouse models of cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2019 Jul 1. pii: AAC.00829.
    PubMed     Abstract available


    June 2019
  68. COLLETT CF, Kitson C, Baker N, Steele-Stallard HB, et al
    Chemogenomic profiling of anti-leishmanial efficacy and resistance in the related kinetoplastid parasite Trypanosoma brucei.
    Antimicrob Agents Chemother. 2019 Jun 3. pii: AAC.00795.
    PubMed     Abstract available


    May 2019
  69. PESSANHA DE CARVALHO L, Sandri TL, Jose Tenorio de Melo E, Fendel R, et al
    Ivermectin impairs the development of sexual and asexual stages of Plasmodium falciparum in vitro.
    Antimicrob Agents Chemother. 2019 May 20. pii: AAC.00085.
    PubMed     Abstract available


  70. PACHECO MA, Kadakia ER, Chaudhary Z, Perkins DJ, et al
    Evolution and genetic diversity of the k13 gene associated with artemisinin delayed parasite clearance in Plasmodium falciparum.
    Antimicrob Agents Chemother. 2019 May 13. pii: AAC.02550.
    PubMed     Abstract available


  71. ROBERT MG, Foguim Tsombeng F, Gendrot M, Diawara S, et al
    Baseline Ex Vivo and Molecular Responses of Plasmodium falciparum Isolates to Piperaquine before Implementation of Dihydroartemisinin-Piperaquine in Senegal.
    Antimicrob Agents Chemother. 2019;63.
    PubMed     Abstract available


    April 2019
  72. PALIC S, Bhairosing P, Beijnen JH, Dorlo TPC, et al
    Host-mediated activity of miltefosine in leishmaniasis through immunomodulation: a systematic review.
    Antimicrob Agents Chemother. 2019 Apr 29. pii: AAC.02507.
    PubMed     Abstract available


  73. GRESTY K, Anderson K, Pasay C, Waters NC, et al
    Polymorphisms in P. falciparum Kelch13 and P. vivax Kelch12 genes in parasites collected from three South Pacific countries prior to extensive exposure to artemisinin combination therapies.
    Antimicrob Agents Chemother. 2019 Apr 29. pii: AAC.00536.
    PubMed     Abstract available


    March 2019
  74. COLLINS KA, Ruckle T, Elliott S, Marquart L, et al
    DSM265 400 mg clears asexual stage parasites but not mature gametocytes from the blood of healthy subjects experimentally infected with Plasmodium falciparum.
    Antimicrob Agents Chemother. 2019 Mar 11. pii: AAC.01837.
    PubMed     Abstract available


  75. DE ARAUJO CB, de Lima LP, Calderano SG, Damasceno FS, et al
    Pep5, a fragment of cyclin D2, shows antiparasitic effects in different stages of the Trypanosoma cruzi life cycle and blocks parasite infectivity.
    Antimicrob Agents Chemother. 2019 Mar 4. pii: AAC.01806.
    PubMed     Abstract available


    February 2019
  76. XU C, Sun H, Wei Q, Li J, et al
    Mutation profile of pfdhfr and pfdhps in Plasmodium falciparum among returned migrant workers in China from Africa.
    Antimicrob Agents Chemother. 2019 Feb 25. pii: AAC.01927.
    PubMed     Abstract available


  77. MIRA-MARTINEZ S, Pickford AK, Rovira-Graells N, Guetens P, et al
    Identification of antimalarial compounds that require CLAG3 for their uptake by P. falciparum-infected erythrocytes.
    Antimicrob Agents Chemother. 2019 Feb 19. pii: AAC.00052.
    PubMed     Abstract available


  78. DIAZ M, de Lucio H, Moreno E, Espuelas S, et al
    NOVEL UREA, THIOUREA AND SELENOUREA DERIVATIVES OF DISELENIDES: SYNTHESIS AND LEISHMANICIDAL ACTIVITY.
    Antimicrob Agents Chemother. 2019 Feb 19. pii: AAC.02200.
    PubMed     Abstract available


  79. TONG JX, Ang SEL, Tan EHN, Tan KSW, et al
    Viability Screen of LOPAC(1280) Reveals Tyrosine Kinase Inhibitor Tyrphostin A9 as a Novel Partner Drug for Artesunate Combinations to Target the Plasmodium falciparum Ring Stage.
    Antimicrob Agents Chemother. 2019 Feb 4. pii: AAC.02389.
    PubMed     Abstract available


    January 2019
  80. LEANG R, Mairet-Khedim M, Chea H, Huy R, et al
    Efficacy and safety of pyronaridine-artesunate plus single-dose primaquine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Cambodia.
    Antimicrob Agents Chemother. 2019 Jan 2. pii: AAC.02242.
    PubMed     Abstract available


    December 2018
  81. GILSON PR, Nguyen W, Poole WA, Teixeira JE, et al
    Evaluation of 4-amino 2-anilinoquinazolines against Plasmodium and other apicomplexan parasites in vitro and in a P. falciparum humanized NOD-scid IL2Rgamma(null) mouse model of malaria.
    Antimicrob Agents Chemother. 2018 Dec 17. pii: AAC.01804.
    PubMed     Abstract available


    November 2018
  82. FERNANDEZ-RUBIO C, Larrea E, Pena Guerrero J, Sesma Herrero E, et al
    LEISHMANICIDAL ACTIVITY OF ISOSELENOCYANATE DERIVATIVES.
    Antimicrob Agents Chemother. 2018 Nov 26. pii: AAC.00904.
    PubMed     Abstract available


  83. BREGLIO KF, Rahman RS, Sa JM, Hott A, et al
    Correction for Breglio et al., "Kelch Mutations in Plasmodium falciparum Protein K13 Do Not Modulate Dormancy after Artemisinin Exposure and Sorbitol Selection In Vitro".
    Antimicrob Agents Chemother. 2018;62.
    PubMed    


  84. BRUNSCHWIG C, Lawrence N, Taylor D, Abay E, et al
    Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".
    Antimicrob Agents Chemother. 2018;62.
    PubMed    


    October 2018
  85. LIMA ML, Abengozar MA, Nacher-Vazquez M, Martinez-Alcazar MP, et al
    Drug repurposing for Leishmania. Molecular basis of the leishmanicidal activity of the antidepressant sertraline.
    Antimicrob Agents Chemother. 2018 Oct 8. pii: AAC.01928.
    PubMed     Abstract available


  86. DEEP DK, Singh R, Kulshrestha A, Wajid S, et al
    Lipase precursor like protein promotes miltefosine tolerance in Leishmania donovani by enhancing parasite infectivity and eliciting anti-inflammatory responses in host macrophages.
    Antimicrob Agents Chemother. 2018 Oct 8. pii: AAC.00666.
    PubMed     Abstract available


    September 2018
  87. LOZANO S, Gamallo P, Gonzalez-Cortes C, Presa Matilla JL, et al
    Gametocytes from K13-propeller mutant Plasmodium falciparum clinical isolates demonstrate reduced susceptibility to dihydroartemisinin in the male gamete exflagellation inhibition assay.
    Antimicrob Agents Chemother. 2018 Sep 17. pii: AAC.01426.
    PubMed     Abstract available


    August 2018
  88. BANDA CG, Dzinjalamala F, Mukaka M, Mallewa J, et al
    Impact of efavirenz, ritonavir-boosted lopinavir and nevirapine based antiretroviral regimens on the pharmacokinetics of lumefantrine and safety of artemether-lumefantrine in falciparum-negative HIV-infected Malawian adults stabilized on antiretrovira
    Antimicrob Agents Chemother. 2018 Aug 27. pii: AAC.01162.
    PubMed     Abstract available


  89. DINI S, Zaloumis S, Cao P, Price RN, et al
    Investigating the efficacy of triple artemisinin-based combination therapies (TACTs) for treating Plasmodium falciparum malaria patients using mathematical modelling.
    Antimicrob Agents Chemother. 2018 Aug 27. pii: AAC.01068.
    PubMed     Abstract available


  90. SEBASTIAN-PEREZ V, Hendrickx S, Munday JC, Kalejaiye T, et al
    Cyclic nucleotide specific phosphodiesterases as potential drug targets for anti-Leishmania therapy.
    Antimicrob Agents Chemother. 2018 Aug 13. pii: AAC.00603.
    PubMed     Abstract available


  91. WIJNANT GJ, Van Bocxlaer K, Fortes Francisco A, Yardley V, et al
    Local skin inflammation in cutaneous leishmaniasis as a source of variable pharmacokinetics and therapeutic efficacy of liposomal amphotericin B.
    Antimicrob Agents Chemother. 2018 Aug 6. pii: AAC.00631.
    PubMed     Abstract available


    July 2018
  92. RODRIGUES GOMES L, Lavigne A, Peterka CL, Brasil P, et al
    Absence of K13 Polymorphism in Plasmodium falciparum Parasites from Brazilian Endemic Areas.
    Antimicrob Agents Chemother. 2018 Jul 30. pii: AAC.00354.
    PubMed     Abstract available


  93. DAS JL, Rulisa S, de Vries PJ, Mens PF, et al
    Population pharmacokinetics of artemether, dihydroartemisinin and lumefantrine in Rwandese pregnant women treated for uncomplicated Plasmodium falciparum malaria.
    Antimicrob Agents Chemother. 2018 Jul 30. pii: AAC.00518.
    PubMed     Abstract available


  94. SOUSA-BATISTA AJ, Escrivani-Oliveira D, Falcao CAB, Philippon CIMDS, et al
    Broad spectrum and safety of oral treatment with a promising nitrosylated chalcone in murine leishmaniasis.
    Antimicrob Agents Chemother. 2018 Jul 16. pii: AAC.00792.
    PubMed     Abstract available


    June 2018
  95. MANHAS R, Tandon S, Sen SS, Tiwari N, et al
    Leishmania parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.00079.
    PubMed     Abstract available


  96. YAO Y, Wu K, Xu M, Yang Y, et al
    Surveillance of genetic variations associated with antimalarial resistance of Plasmodium falciparum from returned migrant workers in Wuhan, Central China.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.02387.
    PubMed     Abstract available


  97. BRUNSCHWIG C, Lawrence N, Taylor D, Abay E, et al
    UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.00012.
    PubMed     Abstract available


  98. KATO KC, de Morais-Teixeira E, Islam A, Leite MF, et al
    Efficacy of Meglumine Antimoniate under Low Polymerization State Orally Administrated in Murine Model of Visceral Leishmaniasis.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00539.
    PubMed     Abstract available


  99. SANTOS SOUZA S, L'Episcopia M, Severini C, Udhayakumar V, et al
    PET-PCR for Detection of Plasmodium falciparum Plasmepsin 2 Gene copy number.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00317.
    PubMed     Abstract available


  100. COERTZEN D, Reader J, van der Watt M, Nondaba SH, et al
    Artemisone and artemiside - potent pan-reactive antimalarial agents that also synergize redox imbalance in P. falciparum transmissible gametocyte stages.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.02214.
    PubMed     Abstract available


  101. MEYER KJ, Caton E, Shapiro TA
    Model system identifies kinetic driver of Hsp90 inhibitor activity against African trypanosomes and Plasmodium falciparum.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00056.
    PubMed     Abstract available


  102. KOVAC J, Meister I, Neodo A, Panic G, et al
    Pharmacokinetics of praziquantel in Schistosoma mansoni and Schistosoma haematobium infected school- and preschool- aged children.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.02253.
    PubMed     Abstract available


    May 2018
  103. YAN HB, Smout MJ, Ju C, Folley AE, et al
    Developmental sensitivity in Schistosoma mansoni to puromycin to establish drug selection of transgenic schistosomes.
    Antimicrob Agents Chemother. 2018 May 14. pii: AAC.02568.
    PubMed     Abstract available


    March 2018
  104. DEMBELE L, Gupta DK, Lim MY, Ang X, et al
    Imidazolopiperazines (IPZ) kill both rings and dormant rings in wild type and K13 artemisinin resistant Plasmodium falciparum in vitro.
    Antimicrob Agents Chemother. 2018 Mar 12. pii: AAC.02235.
    PubMed     Abstract available


  105. VAN BOCXLAER K, Gaukel E, Hauser D, Park SH, et al
    Topical treatment for cutaneous leishmaniasis - dermato-pharmacokinetic led optimisation of benzoxaboroles.
    Antimicrob Agents Chemother. 2018 Mar 5. pii: AAC.02419.
    PubMed     Abstract available


    February 2018
  106. ARMITAGE EG, Alqaisi AQI, Godzien J, Pena I, et al
    A complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the Leishmania metabolome caused by miltefosine.
    Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02095.
    PubMed     Abstract available


  107. BREGLIO KF, Rahman RS, Sa JM, Roberts DJ, et al
    Kelch mutations in Plasmodium falciparum protein K13 do not modulate dormancy after artemisinin exposure and sorbitol selection in vitro.
    Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02256.
    PubMed     Abstract available


  108. MUKHERJEE A, Gagnon D, Wirth DF, Richard D, et al
    Inactivation of Plasmepsin 2 and 3 sensitizes Plasmodium falciparum to the antimalarial drug piperaquine.
    Antimicrob Agents Chemother. 2018 Feb 12. pii: AAC.02309.
    PubMed     Abstract available


    January 2018
  109. KOBASA T, Talundzic E, Sug-Aram R, Boondat P, et al
    The emergence and spread of kelch 13 mutations associated with artemisinin resistance in Plasmodium falciparum parasites in twelve Thai provinces from 2007 - 2016.
    Antimicrob Agents Chemother. 2018 Jan 29. pii: AAC.02141.
    PubMed     Abstract available


  110. DUVALSAINT M, Kyle DE
    Phytohormones, isoprenoids and role of the apicoplast in recovery from dihydroartemisinin-induced dormancy of Plasmodium falciparum.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01771.
    PubMed     Abstract available


  111. TONG JX, Chandramohanadas R, Tan KS
    High-Content Screening of MMV Pathogen Box for Plasmodium falciparum Digestive Vacuole Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.02031.
    PubMed     Abstract available


  112. HARRIS LM, Monsell KR, Noulin F, Famodimu MT, et al
    G-quadruplex DNA motifs in the malaria parasite Plasmodium falciparum and their potential as novel antimalarial drug targets.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01828.
    PubMed     Abstract available


    December 2017
  113. WIJNANT GJ, Van Bocxlaer K, Yardley V, Harris A, et al
    AmBisome(R) treatment of murine cutaneous leishmaniasis: relation between skin pharmacokinetics and efficacy.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.02009.
    PubMed     Abstract available


  114. DE JESUS SOUSA-BATISTA A, Pacienza-Lima W, Arruda-Costa N, Falcao CAB, et al
    Depot subcutaneous injection with chalcone CH8-loaded PLGA microspheres aiming at a single-dose treatment of cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.01822.
    PubMed     Abstract available


  115. MALVY D, Torrentino-Madamet M, L'Ollivier C, Receveur MC, et al
    Plasmodium falciparum Recrudescence Two Years after a First Treated Uncomplicated Infection without Return in a Malaria Endemic Area.
    Antimicrob Agents Chemother. 2017 Dec 11. pii: AAC.01892.
    PubMed     Abstract available


    November 2017
  116. BHALLA P, Sultana S, Chiranjivi AK, Saikia AK, et al
    Synthesis of Methyl 4-(7-hydroxy-4,4,8-trimethyl-3-oxabicyclo[3.3.1]nonan-2-yl)benzoate and their evaluation as anti-leishmanial: Synergistic effect with Miltefosine.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01810.
    PubMed     Abstract available


  117. UDDIN T, McFadden GI, Goodman CD
    Validation of putative apicoplast targeting drugs using a chemical supplementation assay in cultured human malaria parasites.
    Antimicrob Agents Chemother. 2017 Nov 6. pii: AAC.01161.
    PubMed     Abstract available


    October 2017
  118. KONG D, Zhou C, Guo H, Wang W, et al
    Praziquantel targets M1 macrophages and ameliorates splenomegaly in chronic schistosomiasis.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00005.
    PubMed     Abstract available


  119. DAS S, Giri S, Sundar S, Shaha C, et al
    Leishmania donovani Tryparedoxin Peroxidases: functional involvement during infection and drug treatment.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00806.
    PubMed     Abstract available


  120. GARGANO N, Madrid L, Valentini G, D'Alessandro U, et al
    A new water-dispersible paediatric formulation of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in African infants: efficacy and tolerability outcomes of a phase II, randomized, open label, multicenter
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00596.
    PubMed     Abstract available


  121. PINTO-MARTINEZ AK, Rodriguez-Duran J, Serrano-Martin X, Hernandez-Rodriguez V, et al
    Mechanism of action of miltefosine on Leishmania donovani involves the impairment of acidocalcisomes function and the activation of the sphingosine-dependent plasma membrane Ca2+ channel.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.01614.
    PubMed     Abstract available


  122. CAO P, Klonis N, Zaloumis S, Dogovski C, et al
    A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum.
    Antimicrob Agents Chemother. 2017 Oct 9. pii: AAC.00618.
    PubMed     Abstract available


  123. ARCARI T, Manzano JI, Gamarro F
    ABCI3, a new mitochondrial ABC transporter from Leishmania major involved in susceptibility to antimonials and infectivity.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01115.
    PubMed     Abstract available


  124. PANIC G, Ruf MT, Keiser J
    Immunohistochemical investigations of treatment with Ro 13-3978, praziquantel, oxamniquine and mefloquine in Schistosoma mansoni-infected mice.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01142.
    PubMed     Abstract available


  125. AMAMBUA-NGWA A, Okebe J, Mbye H, Ceesay S, et al
    Sustained ex vivo susceptibility of Plasmodium falciparum to artemisinin derivatives but increasing tolerance to ACT partner quinolines in The Gambia.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.00759.
    PubMed     Abstract available


    September 2017
  126. MONTENEGRO M, Neal AT, Posada M, De Las Salas B, et al
    K13-propeller Alleles, Mdr1 Polymorphism, and Drug Effectiveness at Day 3 after Artemether-lumefantrine Treatment for Plasmodium falciparum Malaria in Colombia, 2014-2015.
    Antimicrob Agents Chemother. 2017 Sep 25. pii: AAC.01036.
    PubMed     Abstract available


  127. BOYLE MJ, Skidmore M, Dickerman B, Cooper L, et al
    Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.00709.
    PubMed     Abstract available


    June 2017
  128. VOAK AA, Harris A, Qaiser Z, Croft SL, et al
    Treatment of experimental visceral leishmaniasis with single-dose liposomal amphotericin B - pharmacodynamics and biodistribution at different stages of disease.
    Antimicrob Agents Chemother. 2017 Jun 19. pii: AAC.00497.
    PubMed     Abstract available


  129. IMAN M, Huang Z, Alavizadeh SH, Szoka FC Jr, et al
    Study of Biodistribution and in vivo Anti-leishmanial Activity of a Distigmasterylhemisuccinoyl-glycero-phosphocholine Liposome-intercalated Amphotericin B.
    Antimicrob Agents Chemother. 2017 Jun 19. pii: AAC.02525.
    PubMed     Abstract available


  130. WIJNANT GJ, Van Bocxlaer K, Yardley V, Murdan S, et al
    Efficacy of a Paromomycin plus Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis.
    Antimicrob Agents Chemother. 2017 Jun 12. pii: AAC.00358.
    PubMed     Abstract available


  131. BLAKE LD, Johnson ME, Siegel SV, McQueen A, et al
    Menoctone resistance in malaria parasites is conferred by M133I mutations in cytochrome b that are transmissible through mosquitos.
    Antimicrob Agents Chemother. 2017 Jun 5. pii: AAC.00689.
    PubMed     Abstract available


    May 2017
  132. WIRJANATA G, Handayuni I, Prayoga P, Leonardo L, et al
    Plasmodium falciparum and P. vivax demonstrate contrasting chloroquine resistance reversal phenotypes.
    Antimicrob Agents Chemother. 2017 May 22. pii: AAC.00355.
    PubMed     Abstract available


  133. VELASQUEZ AMA, Ribeiro WC, Venn V, Castelli S, et al
    Efficacy of a Binuclear Cyclopalladated Compound Therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on Topoisomerase 1B.
    Antimicrob Agents Chemother. 2017 May 15. pii: AAC.00688.
    PubMed     Abstract available


  134. TELLEZ J, Romero I, Soares MJ, Steindel M, et al
    KNOCKDOWN OF HOST ANTIOXIDANT DEFENSE GENES ENHANCES THE EFFECT OF GLUCANTIME ON INTRACELLULAR Leishmania braziliensis IN HUMAN MACROPHAGES.
    Antimicrob Agents Chemother. 2017 May 1. pii: AAC.02099.
    PubMed     Abstract available


    April 2017
  135. CHENET SM, Akinyi Okoth S, Kelley J, Lucchi N, et al
    Molecular profile of malaria drug resistance markers of Plasmodium falciparum in Suriname.
    Antimicrob Agents Chemother. 2017 Apr 24. pii: AAC.02655.
    PubMed     Abstract available


    March 2017
  136. MOREIRA VR, de Jesus LC, Soares RP, Silva LD, et al
    Glucantime(R) causes oxidative stress-derived DNA damage in Balb/c mice infected by Leishmania (Leishmania) infantum.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02360.
    PubMed     Abstract available


  137. MARTIN-MONTES A, Plano D, Martin-Escolano R, Alcolea V, et al
    A library of seleno-compounds and Leishmania species: Rising evidences towards novel agents.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02546.
    PubMed     Abstract available


  138. TALUNDZIC E, Ndiaye YD, Deme AB, Olsen C, et al
    Molecular Epidemiology of Plasmodium falciparum kelch13 Mutations in Senegal Determined by Using Targeted Amplicon Deep Sequencing.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


    February 2017
  139. SZAJNMAN SH, Galaka T, Li ZH, Li C, et al
    In Vitro and In Vivo Activities of Sulfur-Containing Linear Bisphosphonates against Apicomplexan Parasites.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


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