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Parasitic Diseases

Free Subscription Articles published in Antimicrob Agents Chemother Retrieve available abstracts of 50 articles: HTML format

Single Articles

October 2025
1. MESQUITA JT, Moura GC, Cavalcante T, Yokoyama Yasunaka JKU, et al
   In vitro and in vivo study of the inhibition of ubiquinone biosynthesis in Leishmania (Leishmania) amazonensis using the combination of buparvaquone and 4-nitrobenzoate as a strategy for the discovery of new therapeutic targets.
   Antimicrob Agents Chemother. 2025 Oct 7:e0082425. doi: 10.1128/aac.00824.
   PubMed     Abstract available
   
   
   September 2025
2. JUNAID IT, Panda A, Deshmukh A, Sardar R, et al
   Role of novel mutations in food vacuole transporters beyond K13-mediated artemisinin resistance in Plasmodium falciparum.
   Antimicrob Agents Chemother. 2025 Sep 30:e0029325. doi: 10.1128/aac.00293.
   PubMed     Abstract available
   
   
   August 2025
3. NIKOLOVA V, Linnemannstons K, Zahoruiko A, Ganter M, et al
   Synergistic activity of RSL3 and Pyrimethamine to inhibit the proliferation of Plasmodium falciparum.
   Antimicrob Agents Chemother. 2025 Aug 18:e0047125. doi: 10.1128/aac.00471.
   PubMed     Abstract available
   
   
   July 2025
4. MAO EY, Nguyen W, Jana GP, Maity BC, et al
   Characterizing the quick-killing mechanism of action of azithromycin analogs against malaria parasites.
   Antimicrob Agents Chemother. 2025 Jul 25:e0178324. doi: 10.1128/aac.01783.
   PubMed     Abstract available
   
   
   
5. MACHADO PDA, Gomes PS, Granato JdT, Lemos ASdO, et al
   Exploring the in vitro and in vivo antileishmanial potential of Marizomib against Leishmania amazonensis and Leishmania infantum.
   Antimicrob Agents Chemother. 2025 Jul 21:e0028625. doi: 10.1128/aac.00286.
   PubMed     Abstract available
   
   
   June 2025
6. SPRINGER E, Heimsch KC, Sidiropoulos N, Krijnse Locker J, et al
   Arylmethylamino steroid compound 1o interferes with Plasmodium falciparum's hemoglobin metabolism.
   Antimicrob Agents Chemother. 2025 Jun 23:e0033225. doi: 10.1128/aac.00332.
   PubMed     Abstract available
   
   
   May 2025
7. SIDDIQUI FA, Chim-Ong A, Wang C, Miao J, et al
   The PfK13 G533S mutation confers artemisinin partial resistance in multiple genetic backgrounds of Plasmodium falciparum.
   Antimicrob Agents Chemother. 2025 May 27:e0016225. doi: 10.1128/aac.00162.
   PubMed     Abstract available
   
   
   
8. RAZZAQ S, Olmo F, Lakshminarayana SB, Ying-Bo C, et al
   Statins do not reduce the parasite burden during experimental Trypanosoma cruzi infection.
   Antimicrob Agents Chemother. 2025;69:e0013525.
   PubMed     Abstract available
   
   
   April 2025
9. VAN LOON W, Schallenberg E, Mande E, Musinguzi P, et al
   Plasmodium falciparum Kelch-13 artemisinin partial resistance markers in Fort Portal, Western Uganda, 2024.
   Antimicrob Agents Chemother. 2025 Apr 23:e0175524. doi: 10.1128/aac.01755.
   PubMed     Abstract available
   
   
   
10. PROELLOCHS NI, Andolina C, Ramjith J, Stoter R, et al
    Gametocyte production and transmission fitness of African and Asian Plasmodium falciparum isolates with differential susceptibility to artemisinins.
    Antimicrob Agents Chemother. 2025 Apr 22:e0193024. doi: 10.1128/aac.01930.
    PubMed     Abstract available
    
    
    
11. KOJOM FOKO LP, Jakhan J, Narang G, Hawadak J, et al
    Novel Plasmodium falciparum Kelch13 polymorphisms in Cameroon with structural and physicochemical impact.
    Antimicrob Agents Chemother. 2025 Apr 14:e0088424. doi: 10.1128/aac.00884.
    PubMed     Abstract available
    
    
    February 2025
12. HIRAI M, Arai M, Hayamichi S, Uchida A, et al
    Deletion of the chloroquine resistance transporter gene confers reduced piperaquine susceptibility to the rodent malaria parasite Plasmodium berghei.
    Antimicrob Agents Chemother. 2025 Feb 24:e0158924. doi: 10.1128/aac.01589.
    PubMed     Abstract available
    
    
    
13. KIBOI D, Sa JM, Nayak A, Micchelli CE, et al
    Isolation and characterization of Plasmodium falciparum blood-stage persisters by improved selection protocols using dihydroartemisinin alone.
    Antimicrob Agents Chemother. 2025 Feb 10:e0005324. doi: 10.1128/aac.00053.
    PubMed     Abstract available
    
    
    
14. PALOQUE L, Mathieu L, Laurent M, Coppee R, et al
    Artemisinin pressure in field isolates can select highly resistant Plasmodium falciparum parasites with unconventional phenotype and no K13 mutation.
    Antimicrob Agents Chemother. 2025 Feb 4:e0154124. doi: 10.1128/aac.01541.
    PubMed     Abstract available
    
    
    January 2025
15. KAR PP, Araveti PB, Saxena K, Borah A, et al
    Erratum for Kar et al., "Cimicifugin, a broad-spectrum inhibitor of Theileria annulata and Plasmodium falciparum CDK7".
    Antimicrob Agents Chemother. 2025 Jan 24:e0178224. doi: 10.1128/aac.01782.
    PubMed    
    
    
    December 2024
16. OBONYO CO, Were VO, Wamae P, Muok EMO, et al
    Efficacy and safety of praziquantel plus artemisinin-based combinations versus praziquantel in the treatment of Kenyan children with Schistosoma mansoni infection: open-label, randomized, head-to-head, non-inferiority trial.
    Antimicrob Agents Chemother. 2024 Dec 19:e0073924. doi: 10.1128/aac.00739.
    PubMed     Abstract available
    
    
    
17. SAYEED A, Atkinson R, Vekilov PG, Rimer JD, et al
    Stage-specific pharmacodynamic chloroquine and pyronaridine action on artemisinin ring-stage resistant Kelch C580Y mutation Plasmodium falciparum correlates to hemozoin inhibition process.
    Antimicrob Agents Chemother. 2024 Dec 12:e0120824. doi: 10.1128/aac.01208.
    PubMed     Abstract available
    
    
    November 2024
18. OKITWI M, Shoue DA, Checkley LA, Orena S, et al
    The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates.
    Antimicrob Agents Chemother. 2024 Nov 15:e0118324. doi: 10.1128/aac.01183.
    PubMed     Abstract available
    
    
    
19. PIERRE-LOUIS E, Kelley J, Patel D, Carlson C, et al
    Geo-classification of drug-resistant travel-associated Plasmodium falciparum using Pfs47 and Pfcpmp gene sequences (USA, 2018-2021).
    Antimicrob Agents Chemother. 2024 Nov 12:e0120324. doi: 10.1128/aac.01203.
    PubMed     Abstract available
    
    
    October 2024
20. HASSANI-ABHARIAN P, Hejazi Dehaghani S, Shahmoradi Z, Hejazi SH, et al
    Therapeutic effect of topical tamoxifen in murine cutaneous leishmaniasis caused by Leishmania major.
    Antimicrob Agents Chemother. 2024 Oct 24:e0035824. doi: 10.1128/aac.00358.
    PubMed     Abstract available
    
    
    
21. RIBEIRO JM, Teixeira EdM, Alves LL, Alves EAR, et al
    Can letrozole be repurposed for the treatment of visceral leishmaniasis?
    Antimicrob Agents Chemother. 2024 Oct 10:e0075624. doi: 10.1128/aac.00756.
    PubMed     Abstract available
    
    
    
22. AMARAL M, Romanelli MM, Asiki H, Bicker J, et al
    Synthesis of a dehydrodieugenol B derivative as a lead compound for visceral leishmaniasis-mechanism of action and in vivo pharmacokinetic studies.
    Antimicrob Agents Chemother. 2024 Oct 9:e0083124. doi: 10.1128/aac.00831.
    PubMed     Abstract available
    
    
    
23. LOOS JA, Negro PS, Ortega HH, Salinas FJ, et al
    Anti-echinococcal effect of metformin in advanced experimental cystic echinococcosis: reprogrammed intermediary carbon metabolism in the parasite.
    Antimicrob Agents Chemother. 2024;68:e0094124.
    PubMed     Abstract available
    
    
    September 2024
24. AHMED AOA, Nkhoma SC, Zaman S, Rashid S, et al
    In vitro antimalarial susceptibility profile of Plasmodium falciparum isolates in the BEI Resources repository.
    Antimicrob Agents Chemother. 2024 Sep 13:e0118923. doi: 10.1128/aac.01189.
    PubMed     Abstract available
    
    
    
25. TULLY MK, Dini S, Flegg JA, McCarthy JS, et al
    Evaluation of a Bayesian hierarchical pharmacokinetic-pharmacodynamic model for predicting parasitological outcomes in Phase 2 studies of new antimalarial drugs.
    Antimicrob Agents Chemother. 2024;68:e0086324.
    PubMed     Abstract available
    
    
    August 2024
26. MIN H, Lucky AB, Madsen JJ, Chim-Ong A, et al
    Onametostat, a PfPRMT5 inhibitor, exhibits antimalarial activity to Plasmodium falciparum.
    Antimicrob Agents Chemother. 2024 Aug 28:e0017624. doi: 10.1128/aac.00176.
    PubMed     Abstract available
    
    
    
27. VYDYAM P, Chand M, Gihaz S, Renard I, et al
    In vitro efficacy of next-generation dihydrotriazines and biguanides against babesiosis and malaria parasites.
    Antimicrob Agents Chemother. 2024 Aug 13:e0042324. doi: 10.1128/aac.00423.
    PubMed     Abstract available
    
    
    
28. KREUTZFELD O, Orena S, Okitwi M, Tumwebaze PK, et al
    Ex vivo susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan Plasmodium falciparum isolates.
    Antimicrob Agents Chemother. 2024 Aug 13:e0046624. doi: 10.1128/aac.00466.
    PubMed     Abstract available
    
    
    
29. THALOENGSOK S, Chaisatit C, Saingam P, Lertsethtakarn P, et al
    Prevalence and dynamics of antimalarial drug resistance mutations among the Plasmodium falciparum isolates in TAK Province, Thailand, during the period of 1998-2001.
    Antimicrob Agents Chemother. 2024 Aug 13:e0077924. doi: 10.1128/aac.00779.
    PubMed     Abstract available
    
    
    
30. OGWANG R, Osoti V, Wamae K, Ndwiga L, et al
    A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda.
    Antimicrob Agents Chemother. 2024 Aug 13:e0157623. doi: 10.1128/aac.01576.
    PubMed     Abstract available
    
    
    July 2024
31. KABECHE S, Braukmann T, Doenier J, Meister T, et al
    A picomolar inhibitor of the Plasmodium falciparum IPP pathway.
    Antimicrob Agents Chemother. 2024 Jul 22:e0123823. doi: 10.1128/aac.01238.
    PubMed     Abstract available
    
    
    
32. AWOR P, Coppee R, Khim N, Rondepierre L, et al
    Indigenous emergence and spread of kelch13 C469Y artemisinin-resistant Plasmodium falciparum in Uganda.
    Antimicrob Agents Chemother. 2024 Jul 19:e0165923. doi: 10.1128/aac.01659.
    PubMed     Abstract available
    
    
    
33. KAR PP, Araveti PB, Saxena K, Borah A, et al
    Cimicifugin, a broad-spectrum inhibitor of Theileria annulata and Plasmodium falciparum CDK7.
    Antimicrob Agents Chemother. 2024 Jul 18:e0044024. doi: 10.1128/aac.00440.
    PubMed     Abstract available
    
    
    June 2024
34. ANNAMALAI SUBRAMANI P, Tipthara P, Kolli SK, Nicholas J, et al
    Efficacy of ivermectin and its metabolites against Plasmodium falciparum liver stages in primary human hepatocytes.
    Antimicrob Agents Chemother. 2024 Jun 21:e0127223. doi: 10.1128/aac.01272.
    PubMed     Abstract available
    
    
    May 2024
35. CAJAS RA, Santos SSB, Espirito-Santo MCC, Garedaghi Y, et al
    In vitro and in vivo efficacy of the amiodarone and praziquantel combination against the blood fluke Schistosoma mansoni.
    Antimicrob Agents Chemother. 2024 May 23:e0011424. doi: 10.1128/aac.00114.
    PubMed     Abstract available
    
    
    April 2024
36. SAITO M, Wilaisrisak P, Pimanpanarak M, Viladpai-Nguen J, et al
    Comparison of lumefantrine, mefloquine, and piperaquine concentrations between capillary plasma and venous plasma samples in pregnant women with uncomplicated falciparum and vivax malaria.
    Antimicrob Agents Chemother. 2024 Apr 10:e0009324. doi: 10.1128/aac.00093.
    PubMed     Abstract available
    
    
    
37. AL KHOURY C, Thoumi S, Tokajian S, Sinno A, et al
    ABC transporter inhibition by beauvericin partially overcomes drug resistance in Leishmania tropica.
    Antimicrob Agents Chemother. 2024 Apr 4:e0136823. doi: 10.1128/aac.01368.
    PubMed     Abstract available
    
    
    March 2024
38. SPRINGER E, Heimsch KC, Rahlfs S, Becker K, et al
    Real-time measurements of ATP dynamics via ATeams in Plasmodium falciparum reveal drug-class-specific response patterns.
    Antimicrob Agents Chemother. 2024 Mar 19:e0169023. doi: 10.1128/aac.01690.
    PubMed     Abstract available
    
    
    
39. YAN M, Liu H, Su Y, Bi X, et al
    Inhibition of AMPK activation in Echinococcus granulosus sensu stricto limits the parasite's glucose metabolism and survival.
    Antimicrob Agents Chemother. 2024;68:e0120223.
    PubMed     Abstract available
    
    
    February 2024
40. SOME AF, Conrad MD, Kabre Z, Fofana A, et al
    Ex vivo drug susceptibility and resistance mediating genetic polymorphisms of Plasmodium falciparum in Bobo-Dioulasso, Burkina Faso.
    Antimicrob Agents Chemother. 2024 Feb 27:e0153423. doi: 10.1128/aac.01534.
    PubMed     Abstract available
    
    
    
41. ROMAN-ALAMO L, Avalos-Padilla Y, Bouzon-Arnaiz I, Iglesias V, et al
    Effect of the aggregated protein dye YAT2150 on Leishmania parasite viability.
    Antimicrob Agents Chemother. 2024 Feb 13:e0112723. doi: 10.1128/aac.01127.
    PubMed     Abstract available
    
    
    January 2024
42. CHEVALIER FD, Le Clec'h W, Berriman M, Anderson TJ, et al
    A single locus determines praziquantel response in Schistosoma mansoni.
    Antimicrob Agents Chemother. 2024 Jan 30:e0143223. doi: 10.1128/aac.01432.
    PubMed     Abstract available
    
    
    
43. GREYLING N, van der Watt M, Gwarinda H, van Heerden A, et al
    Genetic complexity alters drug susceptibility of asexual and gametocyte stages of Plasmodium falciparum to antimalarial candidates.
    Antimicrob Agents Chemother. 2024 Jan 23:e0129123. doi: 10.1128/aac.01291.
    PubMed     Abstract available
    
    
    
44. CHERY-KARSCHNEY L, Patrapuvich R, Mudeppa DG, Kokkonda S, et al
    Tartrolon E, a secondary metabolite of a marine symbiotic bacterium, is a potent inhibitor of asexual and sexual Plasmodium falciparum.
    Antimicrob Agents Chemother. 2024 Jan 9:e0068423. doi: 10.1128/aac.00684.
    PubMed     Abstract available
    
    
    December 2023
45. VAN LOON W, Schallenberg E, Igiraneza C, Habarugira F, et al
    Escalating Plasmodium falciparum K13 marker prevalence indicative of artemisinin resistance in southern Rwanda.
    Antimicrob Agents Chemother. 2023 Dec 11:e0129923. doi: 10.1128/aac.01299.
    PubMed     Abstract available
    
    
    
46. CRUZ MGFDML, Santi AMM, Morais-Teixeira Ed, Caldeira ASP, et al
    Anti-Leishmania compounds can be screened using Leishmania spp. expressing red fluorescence (tdTomato).
    Antimicrob Agents Chemother. 2023 Dec 8:e0050923. doi: 10.1128/aac.00509.
    PubMed     Abstract available
    
    
    November 2023
47. WATANABE N, Saito-Nakano Y, Kurisawa N, Otomo K, et al
    Fumagillin inhibits growth of the enteric protozoan parasite Entamoeba histolytica by covalently binding to and selectively inhibiting methionine aminopeptidase 2.
    Antimicrob Agents Chemother. 2023;67:e0056023.
    PubMed     Abstract available
    
    
    
48. NKEMNGO FN, Raissa LW, Nguete DN, Ndo C, et al
    Geographical emergence of sulfadoxine-pyrimethamine drug resistance-associated P. falciparum and P. malariae alleles in co-existing Anopheles mosquito and asymptomatic human populations across Cameroon.
    Antimicrob Agents Chemother. 2023 Nov 10:e0058823. doi: 10.1128/aac.00588.
    PubMed     Abstract available
    
    
    October 2023
49. TOMAZ KCP, Tavella TA, Borba JVB, Salazar-Alvarez LC, et al
    Identification of potential inhibitors of casein kinase 2 alpha of Plasmodium falciparum with potent in vitro activity.
    Antimicrob Agents Chemother. 2023 Oct 11:e0058923. doi: 10.1128/aac.00589.
    PubMed     Abstract available
    
    
    September 2023
50. LUCKY AB, Wang C, Shakri AR, Kalamuddin M, et al
    Plasmodium falciparum GCN5 plays a key role in regulating artemisinin resistance-related stress responses.
    Antimicrob Agents Chemother. 2023 Sep 13:e0057723. doi: 10.1128/aac.00577.
    PubMed     Abstract available
    
    

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