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  Obesity

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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 29 articles:
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Single Articles


    September 2025
  1. WEED L, Zeitzer JM
    Circadian-informed modeling predicts regional variation in obesity and stroke outcomes under different permanent US time policies.
    Proc Natl Acad Sci U S A. 2025;122:e2508293122.
    PubMed     Abstract available


    July 2025
  2. MCGROSKY A, Luke A, Arab L, Bedu-Addo K, et al
    Energy expenditure and obesity across the economic spectrum.
    Proc Natl Acad Sci U S A. 2025;122:e2420902122.
    PubMed     Abstract available


    May 2025
  3. GUNTER CC, Treadwell DD, Resende MFR Jr, Whitaker VM, et al
    Food Rx: Integrating horticulture research to improve nutrition and health.
    Proc Natl Acad Sci U S A. 2025;122:e2501723122.
    PubMed     Abstract available


    April 2025
  4. NISHIO M, Yamaguchi K, Otani J, Yuguchi K, et al
    MOB1 deletion in murine mature adipocytes ameliorates obesity and diabetes.
    Proc Natl Acad Sci U S A. 2025;122:e2424741122.
    PubMed     Abstract available


  5. ARIYANI W, Yoshikawa C, Tsuneoka H, Amano I, et al
    Dopaminergic neurons in the paraventricular hypothalamus extend the food consumption phase.
    Proc Natl Acad Sci U S A. 2025;122:e2411069122.
    PubMed     Abstract available


  6. CHAIKIN CA, Thakkar AV, Steffeck AWT, Pfrender EM, et al
    Control of circadian muscle glucose metabolism through the BMAL1-HIF axis in obesity.
    Proc Natl Acad Sci U S A. 2025;122:e2424046122.
    PubMed     Abstract available


    February 2025
  7. BARKER DH, Carskadon MA, Gredvig-Ardito C, Hart CN, et al
    Independent effects of the human circadian system and sleep/eating cycles on caloric intake in adolescents vary by weight status.
    Proc Natl Acad Sci U S A. 2025;122:e2407907122.
    PubMed     Abstract available


    December 2024
  8. WOODIE LN, Alberto AJ, Krusen BM, Melink LC, et al
    Genetic synchronization of the brain and liver molecular clocks defend against chrono-metabolic disease.
    Proc Natl Acad Sci U S A. 2024;121:e2417678121.
    PubMed     Abstract available


    November 2024
  9. SCHNEIDER EL, Hangasky JA, Fernandez RDV, Ashley GW, et al
    The limitation of lipidation: Conversion of semaglutide from once-weekly to once-monthly dosing.
    Proc Natl Acad Sci U S A. 2024;121:e2415815121.
    PubMed     Abstract available


    October 2024
  10. PANDEY A, Ye Y, Wells CR, Singer BH, et al
    Estimating the lives that could be saved by expanded access to weight-loss drugs.
    Proc Natl Acad Sci U S A. 2024;121:e2412872121.
    PubMed     Abstract available


  11. TANG R, Harasymowicz NS, Wu CL, Choi YR, et al
    Gene therapy for fat-1 prevents obesity-induced metabolic dysfunction, cellular senescence, and osteoarthritis.
    Proc Natl Acad Sci U S A. 2024;121:e2402954121.
    PubMed     Abstract available


    September 2024
  12. FRIEDMAN JM
    The discovery and development of GLP-1 based drugs that have revolutionized the treatment of obesity.
    Proc Natl Acad Sci U S A. 2024;121:e2415550121.
    PubMed     Abstract available


    August 2024
  13. DU W, Jiang S, Yin S, Wang R, et al
    The microbiota-dependent tryptophan metabolite alleviates high-fat diet-induced insulin resistance through the hepatic AhR/TSC2/mTORC1 axis.
    Proc Natl Acad Sci U S A. 2024;121:e2400385121.
    PubMed     Abstract available


    July 2024
  14. LEE J, Wellenstein K, Rahnavard A, Nelson AT, et al
    Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice.
    Proc Natl Acad Sci U S A. 2024;121:e2318691121.
    PubMed     Abstract available


    May 2024
  15. CHEN J, Liu X, Zou Y, Gong J, et al
    A high-fat diet promotes cancer progression by inducing gut microbiota-mediated leucine production and PMN-MDSC differentiation.
    Proc Natl Acad Sci U S A. 2024;121:e2306776121.
    PubMed     Abstract available


    April 2024
  16. ORELLANA SC, Bethlehem RAI, Simpson-Kent IL, van Harmelen AL, et al
    Childhood maltreatment influences adult brain structure through its effects on immune, metabolic, and psychosocial factors.
    Proc Natl Acad Sci U S A. 2024;121:e2304704121.
    PubMed     Abstract available


  17. CUI A, Xue Y, Su W, Lin J, et al
    Glucose regulation of adipose tissue browning by CBP/p300- and HDAC3-mediated reversible acetylation of CREBZF.
    Proc Natl Acad Sci U S A. 2024;121:e2318935121.
    PubMed     Abstract available


    February 2024
  18. VUJICIC M, Broderick I, Salmantabar P, Perian C, et al
    A macrophage-collagen fragment axis mediates subcutaneous adipose tissue remodeling in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2313185121.
    PubMed     Abstract available


    January 2024
  19. MUNOZ-ROJAS AR, Wang G, Benoist C, Mathis D, et al
    Adipose-tissue regulatory T cells are a consortium of subtypes that evolves with age and diet.
    Proc Natl Acad Sci U S A. 2024;121:e2320602121.
    PubMed     Abstract available


  20. GARCIA-LOPEZ MA, Mora A, Corrales P, Pons T, et al
    DIDO is necessary for the adipogenesis that promotes diet-induced obesity.
    Proc Natl Acad Sci U S A. 2024;121:e2300096121.
    PubMed     Abstract available


  21. YUAN Y, Li K, Ye X, Wen S, et al
    CLCF1 inhibits energy expenditure via suppressing brown fat thermogenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2310711121.
    PubMed     Abstract available


    December 2023
  22. WU Y, Wu C, Shi T, Cai Q, et al
    FAP expression in adipose tissue macrophages promotes obesity and metabolic inflammation.
    Proc Natl Acad Sci U S A. 2023;120:e2303075120.
    PubMed     Abstract available


  23. LI M, Macro J, Meadows K, Mishra D, et al
    Late-life shift in caloric intake affects fly metabolism and longevity.
    Proc Natl Acad Sci U S A. 2023;120:e2311019120.
    PubMed     Abstract available


    September 2023
  24. RAGHANTI MA, Miller EN, Jones DN, Smith HN, et al
    Hedonic eating, obesity, and addiction result from increased neuropeptide Y in the nucleus accumbens during human brain evolution.
    Proc Natl Acad Sci U S A. 2023;120:e2311118120.
    PubMed     Abstract available


    August 2023
  25. DING M, Xu HY, Zhou WY, Xia YF, et al
    CLCF1 signaling restrains thermogenesis and disrupts metabolic homeostasis by inhibiting mitochondrial biogenesis in brown adipocytes.
    Proc Natl Acad Sci U S A. 2023;120:e2305717120.
    PubMed     Abstract available


  26. ADAM RC, Pryce DS, Lee JS, Zhao Y, et al
    Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice.
    Proc Natl Acad Sci U S A. 2023;120:e2309967120.
    PubMed     Abstract available


  27. FANG LZ, Linehan V, Licursi M, Alberto CO, et al
    Prostaglandin E(2) activates melanin-concentrating hormone neurons to drive diet-induced obesity.
    Proc Natl Acad Sci U S A. 2023;120:e2302809120.
    PubMed     Abstract available


    May 2023
  28. HOSOYA T, Oba S, Komiya Y, Kawata D, et al
    Apple-shaped obesity: A risky soil for cytokine-accelerated severity in COVID-19.
    Proc Natl Acad Sci U S A. 2023;120:e2300155120.
    PubMed     Abstract available


    April 2023
  29. BASSE AL, Nielsen KN, Karavaeva I, Ingerslev LR, et al
    NAMPT-dependent NAD(+) biosynthesis controls circadian metabolism in a tissue-specific manner.
    Proc Natl Acad Sci U S A. 2023;120:e2220102120.
    PubMed     Abstract available


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