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By B. S. Kamps et al.


  Obesity

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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 51 articles:
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Single Articles


    December 2024
  1. WOODIE LN, Alberto AJ, Krusen BM, Melink LC, et al
    Genetic synchronization of the brain and liver molecular clocks defend against chrono-metabolic disease.
    Proc Natl Acad Sci U S A. 2024;121:e2417678121.
    PubMed     Abstract available


    November 2024
  2. SCHNEIDER EL, Hangasky JA, Fernandez RDV, Ashley GW, et al
    The limitation of lipidation: Conversion of semaglutide from once-weekly to once-monthly dosing.
    Proc Natl Acad Sci U S A. 2024;121:e2415815121.
    PubMed     Abstract available


    October 2024
  3. PANDEY A, Ye Y, Wells CR, Singer BH, et al
    Estimating the lives that could be saved by expanded access to weight-loss drugs.
    Proc Natl Acad Sci U S A. 2024;121:e2412872121.
    PubMed     Abstract available


  4. TANG R, Harasymowicz NS, Wu CL, Choi YR, et al
    Gene therapy for fat-1 prevents obesity-induced metabolic dysfunction, cellular senescence, and osteoarthritis.
    Proc Natl Acad Sci U S A. 2024;121:e2402954121.
    PubMed     Abstract available


    September 2024
  5. FRIEDMAN JM
    The discovery and development of GLP-1 based drugs that have revolutionized the treatment of obesity.
    Proc Natl Acad Sci U S A. 2024;121:e2415550121.
    PubMed     Abstract available


    August 2024
  6. DU W, Jiang S, Yin S, Wang R, et al
    The microbiota-dependent tryptophan metabolite alleviates high-fat diet-induced insulin resistance through the hepatic AhR/TSC2/mTORC1 axis.
    Proc Natl Acad Sci U S A. 2024;121:e2400385121.
    PubMed     Abstract available


    July 2024
  7. LEE J, Wellenstein K, Rahnavard A, Nelson AT, et al
    Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice.
    Proc Natl Acad Sci U S A. 2024;121:e2318691121.
    PubMed     Abstract available


    May 2024
  8. CHEN J, Liu X, Zou Y, Gong J, et al
    A high-fat diet promotes cancer progression by inducing gut microbiota-mediated leucine production and PMN-MDSC differentiation.
    Proc Natl Acad Sci U S A. 2024;121:e2306776121.
    PubMed     Abstract available


    April 2024
  9. ORELLANA SC, Bethlehem RAI, Simpson-Kent IL, van Harmelen AL, et al
    Childhood maltreatment influences adult brain structure through its effects on immune, metabolic, and psychosocial factors.
    Proc Natl Acad Sci U S A. 2024;121:e2304704121.
    PubMed     Abstract available


  10. CUI A, Xue Y, Su W, Lin J, et al
    Glucose regulation of adipose tissue browning by CBP/p300- and HDAC3-mediated reversible acetylation of CREBZF.
    Proc Natl Acad Sci U S A. 2024;121:e2318935121.
    PubMed     Abstract available


    February 2024
  11. VUJICIC M, Broderick I, Salmantabar P, Perian C, et al
    A macrophage-collagen fragment axis mediates subcutaneous adipose tissue remodeling in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2313185121.
    PubMed     Abstract available


    January 2024
  12. MUNOZ-ROJAS AR, Wang G, Benoist C, Mathis D, et al
    Adipose-tissue regulatory T cells are a consortium of subtypes that evolves with age and diet.
    Proc Natl Acad Sci U S A. 2024;121:e2320602121.
    PubMed     Abstract available


  13. GARCIA-LOPEZ MA, Mora A, Corrales P, Pons T, et al
    DIDO is necessary for the adipogenesis that promotes diet-induced obesity.
    Proc Natl Acad Sci U S A. 2024;121:e2300096121.
    PubMed     Abstract available


  14. YUAN Y, Li K, Ye X, Wen S, et al
    CLCF1 inhibits energy expenditure via suppressing brown fat thermogenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2310711121.
    PubMed     Abstract available


    December 2023
  15. WU Y, Wu C, Shi T, Cai Q, et al
    FAP expression in adipose tissue macrophages promotes obesity and metabolic inflammation.
    Proc Natl Acad Sci U S A. 2023;120:e2303075120.
    PubMed     Abstract available


  16. LI M, Macro J, Meadows K, Mishra D, et al
    Late-life shift in caloric intake affects fly metabolism and longevity.
    Proc Natl Acad Sci U S A. 2023;120:e2311019120.
    PubMed     Abstract available


    September 2023
  17. RAGHANTI MA, Miller EN, Jones DN, Smith HN, et al
    Hedonic eating, obesity, and addiction result from increased neuropeptide Y in the nucleus accumbens during human brain evolution.
    Proc Natl Acad Sci U S A. 2023;120:e2311118120.
    PubMed     Abstract available


    August 2023
  18. DING M, Xu HY, Zhou WY, Xia YF, et al
    CLCF1 signaling restrains thermogenesis and disrupts metabolic homeostasis by inhibiting mitochondrial biogenesis in brown adipocytes.
    Proc Natl Acad Sci U S A. 2023;120:e2305717120.
    PubMed     Abstract available


  19. ADAM RC, Pryce DS, Lee JS, Zhao Y, et al
    Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice.
    Proc Natl Acad Sci U S A. 2023;120:e2309967120.
    PubMed     Abstract available


  20. FANG LZ, Linehan V, Licursi M, Alberto CO, et al
    Prostaglandin E(2) activates melanin-concentrating hormone neurons to drive diet-induced obesity.
    Proc Natl Acad Sci U S A. 2023;120:e2302809120.
    PubMed     Abstract available


    May 2023
  21. HOSOYA T, Oba S, Komiya Y, Kawata D, et al
    Apple-shaped obesity: A risky soil for cytokine-accelerated severity in COVID-19.
    Proc Natl Acad Sci U S A. 2023;120:e2300155120.
    PubMed     Abstract available


    April 2023
  22. BASSE AL, Nielsen KN, Karavaeva I, Ingerslev LR, et al
    NAMPT-dependent NAD(+) biosynthesis controls circadian metabolism in a tissue-specific manner.
    Proc Natl Acad Sci U S A. 2023;120:e2220102120.
    PubMed     Abstract available


    January 2023
  23. DE SIQUEIRA MK, Andrade-Oliveira V, Stacy A, Pedro Torres Guimaraes J, et al
    Infection-elicited microbiota promotes host adaptation to nutrient restriction.
    Proc Natl Acad Sci U S A. 2023;120:e2214484120.
    PubMed     Abstract available


  24. FOURNIER F, Diaz-Marin R, Pilon F, Neault M, et al
    Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis.
    Proc Natl Acad Sci U S A. 2023;120:e2209973120.
    PubMed     Abstract available


    December 2022
  25. JUNG YH, Wang HV, Ruiz D, Bixler BJ, et al
    Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of BPA-induced obesity.
    Proc Natl Acad Sci U S A. 2022;119:e2214988119.
    PubMed     Abstract available


    November 2022
  26. OSBORN LJ, Schultz K, Massey W, DeLucia B, et al
    A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis.
    Proc Natl Acad Sci U S A. 2022;119:e2202934119.
    PubMed     Abstract available


    October 2022
  27. BANKS MA
    Brown fat holds promise for addressing obesity and a host of related ills.
    Proc Natl Acad Sci U S A. 2022;119:e2216435119.
    PubMed    


  28. ROY R, Yang J, Shimura T, Merritt L, et al
    Escape from breast tumor dormancy: The convergence of obesity and menopause.
    Proc Natl Acad Sci U S A. 2022;119:e2204758119.
    PubMed     Abstract available


  29. DU Q, Wu J, Fischer C, Seki T, et al
    Generation of mega brown adipose tissue in adults by controlling brown adipocyte differentiation in vivo.
    Proc Natl Acad Sci U S A. 2022;119:e2203307119.
    PubMed     Abstract available


    June 2022
  30. BYUN S, Lee CH, Jeong H, Kim H, et al
    Loss of adipose TET proteins enhances beta-adrenergic responses and protects against obesity by epigenetic regulation of beta3-AR expression.
    Proc Natl Acad Sci U S A. 2022;119:e2205626119.
    PubMed     Abstract available


    March 2022
  31. JOUFFE C, Weger BD, Martin E, Atger F, et al
    Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
    Proc Natl Acad Sci U S A. 2022;119:e2200083119.
    PubMed     Abstract available


  32. RADFORD-SMITH DE, Probert F, Burnet PWJ, Anthony DC, et al
    Modifying the maternal microbiota alters the gut-brain metabolome and prevents emotional dysfunction in the adult offspring of obese dams.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    February 2022
  33. COX MA
    Countering obesity with eosinophils and sympathetic fat.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed    


    December 2021
  34. SUN W, Dong H, Wolfrum C
    Local acetate inhibits brown adipose tissue function.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  35. YONG Y, Cakir I, Lining Pan P, Biddinger JE, et al
    Endogenous cannabinoids are required for MC4R-mediated control of energy homeostasis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  36. RAVINDRAN S
    Profile of John R. Speakman.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    July 2021

  37. Correction for Edwards et al., Exhaled aerosol increases with COVID-19 infection, age, and obesity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    April 2021
  38. YANG YC, Walsh CE, Johnson MP, Belsky DW, et al
    Life-course trajectories of body mass index from adolescence to old age: Racial and educational disparities.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  39. KAJIMURA S
    The epigenetic regulation of adipose tissue plasticity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


    March 2021
  40. GENG J, Ji B, Li G, Lopez-Isunza F, et al
    CODY enables quantitatively spatiotemporal predictions on in vivo gut microbial variability induced by diet intervention.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  41. PARK YJ, Lee S, Lim S, Nahmgoong H, et al
    DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  42. EDWARDS DA, Ausiello D, Salzman J, Devlin T, et al
    Exhaled aerosol increases with COVID-19 infection, age, and obesity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  43. DING L, Zhang E, Yang Q, Jin L, et al
    Vertical sleeve gastrectomy confers metabolic improvements by reducing intestinal bile acids and lipid absorption in mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  44. PRICE NL, Zhang X, Fernandez-Tussy P, Singh AK, et al
    Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  45. GAO Y, Chen X, He Q, Gimple RC, et al
    Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin.
    Proc Natl Acad Sci U S A. 2020;117:33295-33304.
    PubMed     Abstract available


  46. YUEH MF, He F, Chen C, Vu C, et al
    Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced nonalcoholic fatty liver disease.
    Proc Natl Acad Sci U S A. 2020;117:31259-31266.
    PubMed     Abstract available


  47. JAIN S, Pydi SP, Toti KS, Robaye B, et al
    Lack of adipocyte purinergic P2Y6 receptor greatly improves whole body glucose homeostasis.
    Proc Natl Acad Sci U S A. 2020;117:30763-30774.
    PubMed     Abstract available


    November 2020
  48. BARUCH A, Wong C, Chinn LW, Vaze A, et al
    Antibody-mediated activation of the FGFR1/Klothobeta complex corrects metabolic dysfunction and alters food preference in obese humans.
    Proc Natl Acad Sci U S A. 2020;117:28992-29000.
    PubMed     Abstract available


  49. GERA S, Sant D, Haider S, Korkmaz F, et al
    First-in-class humanized FSH blocking antibody targets bone and fat.
    Proc Natl Acad Sci U S A. 2020;117:28971-28979.
    PubMed     Abstract available


    October 2020
  50. RAPUANO KM, Laurent JS, Hagler DJ Jr, Hatton SN, et al
    Nucleus accumbens cytoarchitecture predicts weight gain in children.
    Proc Natl Acad Sci U S A. 2020;117:26977-26984.
    PubMed     Abstract available


  51. BONOMO RR, Cook TM, Gavini CK, White CR, et al
    Fecal transplantation and butyrate improve neuropathic pain, modify immune cell profile, and gene expression in the PNS of obese mice.
    Proc Natl Acad Sci U S A. 2020 Oct 5. pii: 2006065117.
    PubMed     Abstract available


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