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  Obesity

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Articles published in Metabolism

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Single Articles


    April 2024
  1. AWAZAWA M, Matsushita M, Nomura I, Kobayashi N, et al
    Imeglimin improves systemic metabolism by targeting brown adipose tissue and gut microbiota in obese model mice.
    Metabolism. 2024;153:155796.
    PubMed     Abstract available


  2. ROSENDO-SILVA D, Gomes PB, Rodrigues T, Viana S, et al
    Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction.
    Metabolism. 2024;153:155788.
    PubMed     Abstract available


    March 2024
  3. PENDERGRAST LA, Ashcroft SP, Ehrlich AM, Treebak JT, et al
    Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice.
    Metabolism. 2024 Mar 11:155834. doi: 10.1016/j.metabol.2024.155834.
    PubMed     Abstract available


  4. MENG M, Cao Y, Qiu J, Shan G, et al
    Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner.
    Metabolism. 2024;152:155784.
    PubMed     Abstract available


  5. KOKKINOS A, Tsilingiris D, Simati S, Stefanakis K, et al
    Bariatric surgery, through beneficial effects on underlying mechanisms, improves cardiorenal and liver metabolic risk over an average of ten years of observation: A longitudinal and a case-control study.
    Metabolism. 2024;152:155773.
    PubMed     Abstract available


  6. REGMI P, Young M, Minigo G, Milic N, et al
    Photoperiod and metabolic health: evidence, mechanism, and implications.
    Metabolism. 2024;152:155770.
    PubMed     Abstract available


  7. LAVILLE M, Robert M, Segrestin B
    Barriers to metabolic surgery and how to address them.
    Metabolism. 2024;152:155764.
    PubMed     Abstract available


    February 2024
  8. RACHELLE H, Malak G, Houry P, Marc H, et al
    Mortality risk in patients with obesity and COVID-19 infection: a systematic review and meta-analysis.
    Metabolism. 2024 Feb 13:155812. doi: 10.1016/j.metabol.2024.155812.
    PubMed     Abstract available


  9. SARABHAI T, Kahl S, Gancheva S, Mastrototaro L, et al
    Loss of mitochondrial adaptation associates with deterioration of mitochondrial turnover and structure in metabolic dysfunction-associated steatotic liver disease.
    Metabolism. 2024;151:155762.
    PubMed     Abstract available


  10. SAMARASINGHE SNS, Woods C, Miras AD
    Bariatric Surgery in Women with Polycystic Ovary Syndrome.
    Metabolism. 2024;151:155745.
    PubMed     Abstract available


  11. TSILINGIRIS D, Kokkinos A
    Advances in obesity pharmacotherapy; learning from metabolic surgery and beyond.
    Metabolism. 2024;151:155741.
    PubMed     Abstract available


  12. MURPHY E, Finucane FM
    Addressing uncertainty about the role of structured lifestyle modification for metabolic surgery patients.
    Metabolism. 2024;151:155739.
    PubMed     Abstract available


  13. BAUZA-THORBRUGGE M, Vujicic M, Chanclon B, Palsdottir V, et al
    Adiponectin stimulates Sca1(+)CD34(-)-adipocyte precursor cells associated with hyperplastic expansion and beiging of brown and white adipose tissue.
    Metabolism. 2024;151:155716.
    PubMed     Abstract available


    January 2024
  14. FUKUSHIMA T, Maetani T, Chubachi S, Tanabe N, et al
    Epicardial adipose tissue measured from analysis of adipose tissue area using chest CT imaging is the best potential predictor of COVID-19 severity.
    Metabolism. 2024;150:155715.
    PubMed     Abstract available


  15. ZIQUBU K, Dludla PV, Mabhida SE, Jack BU, et al
    Brown adipose tissue-derived metabolites and their role in regulating metabolism.
    Metabolism. 2024;150:155709.
    PubMed     Abstract available


    October 2023
  16. STEINBACH E, Masi D, Ribeiro A, Serradas P, et al
    Upper small intestine microbiome in obesity and related metabolic disorders: A new field of investigation.
    Metabolism. 2023 Oct 24:155712. doi: 10.1016/j.metabol.2023.155712.
    PubMed     Abstract available


  17. KARAKASIS P, Patoulias D, Pamporis K, Stachteas P, et al
    Safety and efficacy of the new, oral, small-molecule, GLP-1 receptor agonists orforglipron and danuglipron for the treatment of type 2 diabetes and obesity: systematic review and meta-analysis of randomized controlled trials.
    Metabolism. 2023 Oct 16:155710. doi: 10.1016/j.metabol.2023.155710.
    PubMed     Abstract available


  18. TSUKAMOTO S, Suzuki T, Wakui H, Uehara T, et al
    Angiotensin II type 1 receptor-associated protein in immune cells: a possible key factor in the pathogenesis of visceral obesity.
    Metabolism. 2023;149:155706.
    PubMed     Abstract available


  19. ULLAH R, Shen Y, Zhou YD, Fu J, et al
    Perinatal metabolic inflammation in the hypothalamus impairs the development of homeostatic feeding circuitry.
    Metabolism. 2023;147:155677.
    PubMed     Abstract available


    September 2023
  20. KOKKORAKIS M, Katsarou A, Katsiki N, Mantzoros CS, et al
    Milestones in the journey towards addressing obesity; Past trials and triumphs, recent breakthroughs, and an exciting future in the era of emerging effective medical therapies and integration of effective medical therapies with metabolic surgery.
    Metabolism. 2023;148:155689.
    PubMed     Abstract available


  21. CHEN W, Cui W, Wu J, Zheng W, et al
    Blocking IL-6 signaling improves glucose tolerance via SLC39A5-mediated suppression of glucagon secretion.
    Metabolism. 2023;146:155641.
    PubMed     Abstract available


    August 2023
  22. POLYZOS SA, Vachliotis ID, Mantzoros CS
    Sarcopenia, sarcopenic obesity and nonalcoholic fatty liver disease.
    Metabolism. 2023 Aug 4:155676. doi: 10.1016/j.metabol.2023.155676.
    PubMed     Abstract available


  23. HOFFMANN A, Meir AY, Hagemann T, Czechowski P, et al
    A polyphenol-rich green Mediterranean diet enhances epigenetic regulatory potential: the DIRECT PLUS randomized controlled trial.
    Metabolism. 2023;145:155594.
    PubMed     Abstract available


  24. PARK SH, Helsley RN, Fadhul T, Willoughby JLS, et al
    Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD.
    Metabolism. 2023;145:155591.
    PubMed     Abstract available


    July 2023
  25. FERNANDEZ-SAEZ EM, Losarcos M, Becerril S, Valenti V, et al
    Uroguanylin prevents hepatic steatosis, mitochondrial dysfunction and fibrosis in obesity-associated NAFLD.
    Metabolism. 2023 Jul 28:155663. doi: 10.1016/j.metabol.2023.155663.
    PubMed     Abstract available


  26. MUTURI HT, Ghadieh HE, Abdolahipour R, Stankus HL, et al
    Loss of CEACAM1 in endothelial cells causes hepatic fibrosis.
    Metabolism. 2023;144:155562.
    PubMed     Abstract available


    June 2023
  27. KOSCHKER AC, Warrings B, Morbach C, Seyfried F, et al
    Effect of bariatric surgery on cardio-psycho-metabolic outcomes in severe obesity: A randomized controlled trial.
    Metabolism. 2023 Jun 30:155655. doi: 10.1016/j.metabol.2023.155655.
    PubMed     Abstract available


  28. JUNG EJ, Sung KW, Bae TH, Kim HY, et al
    The N-degron pathway mediates lipophagy: The chemical modulation of lipophagy in obesity and NAFLD.
    Metabolism. 2023 Jun 27:155644. doi: 10.1016/j.metabol.2023.155644.
    PubMed     Abstract available


  29. AXELROD CL, Dantas WS, Kirwan JP
    Sarcopenic obesity: emerging mechanisms and therapeutic potential.
    Metabolism. 2023 Jun 26:155639. doi: 10.1016/j.metabol.2023.155639.
    PubMed     Abstract available


  30. WEI F, Gu Y, He L, Kapoor A, et al
    HSD17B6 delays type 2 diabetes development via inhibiting SREBP activation.
    Metabolism. 2023;145:155631.
    PubMed     Abstract available


  31. BOUTARI C, Hill MA, Procaccini C, Matarese G, et al
    The key role of inflammation in the pathogenesis and management of obesity and CVD.
    Metabolism. 2023 Jun 9:155627. doi: 10.1016/j.metabol.2023.155627.
    PubMed    


  32. OH J, Park C, Kim S, Kim M, et al
    High levels of intracellular endotrophin in adipocytes mediate COPII vesicle supplies to autophagosome to impair autophagic flux and contribute to systemic insulin resistance in obesity.
    Metabolism. 2023 Jun 9:155629. doi: 10.1016/j.metabol.2023.155629.
    PubMed     Abstract available


  33. DE OLIVEIRA MC, Silveira ALM, de Oliveira ACC, Lana JP, et al
    Eosinophils protect from metabolic alterations triggered by obesity.
    Metabolism. 2023 Jun 7:155613. doi: 10.1016/j.metabol.2023.155613.
    PubMed     Abstract available


  34. LIU B, Zhong Y, Huang D, Yang L, et al
    LncRNA Nron deficiency protects mice from diet-induced adiposity and hepatic steatosis.
    Metabolism. 2023 Jun 3:155609. doi: 10.1016/j.metabol.2023.155609.
    PubMed     Abstract available


  35. WANG H, Xiong Q, He G, Tang J, et al
    Hepatic IDH2 regulates glycolysis and gluconeogenesis.
    Metabolism. 2023;143:155559.
    PubMed     Abstract available


  36. BARAZZONI R, Cederholm T, Zanetti M, Gortan Cappellari G, et al
    Defining and diagnosing sarcopenia: Is the glass now half full?
    Metabolism. 2023;143:155558.
    PubMed     Abstract available


  37. BRETHVAD AO, Zakariassen HL, Holt J, Lundgren JR, et al
    Increased meal-induced neurotensin response predicts successful maintenance of weight loss - Data from a randomized controlled trial.
    Metabolism. 2023;143:155534.
    PubMed     Abstract available


    May 2023
  38. CAPPELLARI GG, Semolic A, Zanetti M, Vinci P, et al
    Sarcopenic obesity in free-living older adults detected by the ESPEN-EASO consensus diagnostic algorithm: Validation in an Italian cohort and predictive value of insulin resistance and altered plasma ghrelin profile.
    Metabolism. 2023 May 26:155595. doi: 10.1016/j.metabol.2023.155595.
    PubMed     Abstract available


  39. JAVAID HMA, Ko E, Joo EJ, Kwon SH, et al
    TNFalpha-induced NLRP3 inflammasome mediates adipocyte dysfunction and activates macrophages through adipocyte-derived lipocalin 2.
    Metabolism. 2023;142:155527.
    PubMed     Abstract available


    April 2023
  40. PARK MJ, Choi KM
    Interplay of skeletal muscle and adipose tissue: sarcopenic obesity.
    Metabolism. 2023 Apr 29:155577. doi: 10.1016/j.metabol.2023.155577.
    PubMed     Abstract available


  41. GUO X, Hu J, He G, Chen J, et al
    Loss of APOO (MIC26) aggravates obesity-related whitening of brown adipose tissue via PPARalpha-mediated functional interplay between mitochondria and peroxisomes.
    Metabolism. 2023 Apr 21:155564. doi: 10.1016/j.metabol.2023.155564.
    PubMed     Abstract available


  42. CHONG B, Kong G, Shankar K, Chew HSJ, et al
    The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000-2019.
    Metabolism. 2023;141:155402.
    PubMed     Abstract available


  43. REBELOS E, Mari A, Oikonen V, Iida H, et al
    Evaluation of renal glucose uptake with [(18)F]FDG-PET: Methodological advancements and metabolic outcomes.
    Metabolism. 2023;141:155382.
    PubMed     Abstract available


    March 2023
  44. PAPADOPOULOS G, Legaki AI, Georgila K, Vorkas P, et al
    Integrated omics analysis for characterization of the contribution of high fructose corn syrup to non-alcoholic fatty liver disease in obesity.
    Metabolism. 2023 Mar 28:155552. doi: 10.1016/j.metabol.2023.155552.
    PubMed     Abstract available


  45. BIANZANO S, Henrich A, Herich L, Kalsch B, et al
    Efficacy and safety of the ghrelin-O-acyltransferase inhibitor BI 1356225 in overweight/obesity: Data from two Phase I, randomised, placebo-controlled studies.
    Metabolism. 2023 Mar 21:155550. doi: 10.1016/j.metabol.2023.155550.
    PubMed     Abstract available


  46. XU H, Yu W, Sun M, Bi Y, et al
    Syntaxin17 contributes to obesity cardiomyopathy through promoting mitochondrial Ca(2+) overload in a Parkin-MCUb-dependent manner.
    Metabolism. 2023 Mar 20:155551. doi: 10.1016/j.metabol.2023.155551.
    PubMed     Abstract available


  47. LUO X, Li Z, Chen L, Zhang X, et al
    Monocarboxylate transporter 1 in the liver modulates high-fat diet-induced obesity and hepatic steatosis in mice.
    Metabolism. 2023 Mar 16:155537. doi: 10.1016/j.metabol.2023.155537.
    PubMed     Abstract available


  48. MARLENE C, Christos MS
    Advances in physiology, design and development of novel medications changing the landscape of obesity pharmacotherapy.
    Metabolism. 2023 Mar 2:155531. doi: 10.1016/j.metabol.2023.155531.
    PubMed    


    February 2023
  49. MILBANK E, Dragano N, Vidal-Gomez X, Rivas-Limeres V, et al
    Small extracellular vesicle targeting of hypothalamic AMPKalpha1 promotes weight loss in leptin receptor deficient mice.
    Metabolism. 2023;139:155350.
    PubMed     Abstract available


    January 2023
  50. BENEDICTE G, Sara F, Paul L, Laetitia N, et al
    Early humoral response to COVID-19 vaccination in patients living with obesity and diabetes in France. The COVPOP OBEDIAB study with results from the ANRS0001S COV-POPART cohort.
    Metabolism. 2023 Jan 30:155412. doi: 10.1016/j.metabol.2023.155412.
    PubMed     Abstract available


  51. AHMED M, Makinen VP, Lumsden A, Boyle T, et al
    Metabolic profile predicts incident cancer: A large-scale population study in the UK Biobank.
    Metabolism. 2023;138:155342.
    PubMed     Abstract available


  52. DISCHINGER U, Kotzner L, Kovatcheva-Datchary P, Kleinschmidt H, et al
    Hypothalamic integrity is necessary for sustained weight loss after bariatric surgery: A prospective, cross-sectional study.
    Metabolism. 2023;138:155341.
    PubMed     Abstract available


    December 2022
  53. RAJAN S, Hofer P, Christiano A, Stevenson M, et al
    Microsomal triglyceride transfer protein regulates intracellular lipolysis in adipocytes independent of its lipid transfer activity.
    Metabolism. 2022;137:155331.
    PubMed     Abstract available


  54. LARSSON SC, Spyrou N, Mantzoros CS
    Body fatness associations with cancer: evidence from recent epidemiological studies and future directions.
    Metabolism. 2022;137:155326.
    PubMed     Abstract available


    November 2022
  55. XIE H, Wang YH, Liu X, Gao J, et al
    SUMOylation of ERp44 enhances Ero1alpha ER retention contributing to the pathogenesis of obesity and insulin resistance.
    Metabolism. 2022 Nov 22:155351. doi: 10.1016/j.metabol.2022.155351.
    PubMed     Abstract available


  56. ANGELIDI AM, Kokkinos A, Sanoudou D, Connelly MA, et al
    Early metabolomic, lipid and lipoprotein changes in response to medical and surgical therapeutic approaches to obesity.
    Metabolism. 2022 Nov 11:155346. doi: 10.1016/j.metabol.2022.155346.
    PubMed     Abstract available


  57. YANG HM, Kim J, Shin D, Kim JY, et al
    Resistin impairs mitochondrial homeostasis via cyclase-associated protein 1-mediated fission, leading to obesity-induced metabolic diseases.
    Metabolism. 2022;138:155343.
    PubMed     Abstract available


  58. HEIANZA Y, Wang X, Rood J, Clish CB, et al
    Changes in circulating bile acid subtypes in response to weight-loss diets are associated with improvements in glycemic status and insulin resistance: The POUNDS Lost trial.
    Metabolism. 2022;136:155312.
    PubMed     Abstract available


    October 2022
  59. DEMARSILIS A, Reddy N, Boutari C, Filippaios A, et al
    Pharmacotherapy of type 2 diabetes: An update and future directions.
    Metabolism. 2022 Oct 11:155332. doi: 10.1016/j.metabol.2022.155332.
    PubMed     Abstract available


    August 2022
  60. CHAO Y, Gao L, Wang X, Cai Y, et al
    Dysregulated adipose tissue expansion and impaired adipogenesis in Prader-Willi syndrome children before obesity-onset.
    Metabolism. 2022 Aug 22:155295. doi: 10.1016/j.metabol.2022.155295.
    PubMed     Abstract available


  61. FERNANDEZ-GARCIA JC, Barrios-Rodriguez R, Asenjo-Plaza M, Ramos-Molina B, et al
    Metformin, testosterone, or both in men with obesity and low testosterone: A double-blind, parallel-group, randomized controlled trial.
    Metabolism. 2022 Aug 16:155290. doi: 10.1016/j.metabol.2022.155290.
    PubMed     Abstract available


  62. SHIN J, Toyoda S, Nishitani S, Onodera T, et al
    SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1.
    Metabolism. 2022;133:155236.
    PubMed     Abstract available


    July 2022
  63. CHEN KW, Chen YS, Chen PJ, Yeh SH, et al
    Androgen receptor functions in pericentral hepatocytes to decrease gluconeogenesis and avoid hyperglycemia and obesity in male mice.
    Metabolism. 2022 Jul 29:155269. doi: 10.1016/j.metabol.2022.155269.
    PubMed     Abstract available


    June 2022
  64. DU M, Li X, Xiao F, Fu Y, et al
    Serine active site containing protein 1 depletion alters lipid metabolism and protects against high fat diet-induced obesity in mice.
    Metabolism. 2022 Jun 24:155244. doi: 10.1016/j.metabol.2022.155244.
    PubMed     Abstract available


  65. VALENZUELA-VALLEJO L, Chrysafi P, Bello-Ramos J, Bsata S, et al
    Circulating total and intact GDF-15 levels are not altered in response to weight loss induced by liraglutide or lorcaserin treatment in humans with obesity.
    Metabolism. 2022 Jun 11:155237. doi: 10.1016/j.metabol.2022.155237.
    PubMed     Abstract available


    May 2022
  66. BOUTARI C, Mantzoros CS
    A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on.
    Metabolism. 2022 May 15:155217. doi: 10.1016/j.metabol.2022.155217.
    PubMed     Abstract available


  67. CAO C, Koh HE, Van Vliet S, Patterson BW, et al
    Increased plasma fatty acid clearance, not fatty acid concentration, is associated with muscle insulin resistance in people with obesity.
    Metabolism. 2022 May 13:155216. doi: 10.1016/j.metabol.2022.155216.
    PubMed     Abstract available


  68. KIM YJ, Kim HJ, Lee SG, Kim DH, et al
    Aerobic exercise for eight weeks provides protective effects towards liver and cardiometabolic health and adipose tissue remodeling under metabolic stress for one week: A study in mice.
    Metabolism. 2022;130:155178.
    PubMed     Abstract available


  69. SHE QY, Bao JF, Wang HZ, Liang H, et al
    Fibroblast growth factor 21: A "rheostat" for metabolic regulation?
    Metabolism. 2022;130:155166.
    PubMed     Abstract available


  70. ZITTING KM, Vetrivelan R, Yuan RK, Vujovic N, et al
    Chronic circadian disruption on a high-fat diet impairs glucose tolerance.
    Metabolism. 2022;130:155158.
    PubMed     Abstract available


    April 2022
  71. CHENG Y, Han J, Li Q, Shi Y, et al
    Metabolic obesity phenotypes: a friend or foe of digestive polyps?-An observational study based on National Inpatient Database.
    Metabolism. 2022 Apr 12:155201. doi: 10.1016/j.metabol.2022.155201.
    PubMed     Abstract available


  72. UM JH, Park SY, Hur JH, Lee HY, et al
    Bone morphogenic protein 9 is a novel thermogenic hepatokine secreted in response to cold exposure.
    Metabolism. 2022;129:155139.
    PubMed     Abstract available


    March 2022
  73. DU K, Sun L, Luo Z, Cao Y, et al
    Reduced DMPC and PMPC in lung surfactant promote SARS-CoV-2 infection in obesity.
    Metabolism. 2022 Mar 17:155181. doi: 10.1016/j.metabol.2022.155181.
    PubMed     Abstract available


  74. FRUHBECK G, Becerril S, Martin M, Ramirez B, et al
    High plasma and lingual uroguanylin as potential contributors to changes in food preference after sleeve gastrectomy.
    Metabolism. 2022;128:155119.
    PubMed     Abstract available


  75. KAPLANIAN M, Philippe C, Eid SA, Hackl MT, et al
    Deciphering metformin action in obese mice: A critical re-evaluation of established protocols.
    Metabolism. 2022;128:154956.
    PubMed     Abstract available


    February 2022
  76. SON Y, Choi C, Saha A, Park JH, et al
    REEP6 knockout leads to defective beta-adrenergic signaling in adipocytes and promotes obesity-related metabolic dysfunction.
    Metabolism. 2022 Feb 9:155159. doi: 10.1016/j.metabol.2022.155159.
    PubMed     Abstract available


    January 2022
  77. QU HQ, Qu J, Glessner J, Hakonarson H, et al
    Mendelian randomization study of obesity and type 2 diabetes in hospitalized COVID-19 patients.
    Metabolism. 2022 Jan 28:155156. doi: 10.1016/j.metabol.2022.155156.
    PubMed     Abstract available


  78. PORFLITT-RODRIGUEZ M, Guzman-Arriagada V, Sandoval-Valderrama R, Tam CS, et al
    Effects of aerobic exercise on fibroblast growth factor 21 in overweight and obesity. A systematic review.
    Metabolism. 2022 Jan 14:155137. doi: 10.1016/j.metabol.2022.155137.
    PubMed     Abstract available


  79. GONZALEZ-GARCIA I, Freire-Agulleiro O, Nakaya N, Ortega FJ, et al
    Olfactomedin 2 deficiency protects against diet-induced obesity.
    Metabolism. 2022 Jan 10:155122. doi: 10.1016/j.metabol.2021.155122.
    PubMed     Abstract available


  80. SANOUDOU D, Hill MA, Belanger MJ, Arao K, et al
    Editorial: Obesity, metabolic phenotypes and COVID-19.
    Metabolism. 2022 Jan 10:155121. doi: 10.1016/j.metabol.2021.155121.
    PubMed    


  81. LO T, Lee Y, Tseng CY, Hu Y, et al
    Daily transient coating of the intestine leads to weight loss and improved glucose tolerance.
    Metabolism. 2022;126:154917.
    PubMed     Abstract available


  82. TAN EX, Lee JW, Jumat NH, Chan WK, et al
    Non-obese non-alcoholic fatty liver disease (NAFLD) in Asia: an international registry study.
    Metabolism. 2022;126:154911.
    PubMed     Abstract available


    December 2021
  83. KAUR V, Dimitriadis GK, Perez-Pevida B, Bansi DS, et al
    Mechanisms of action of duodenal mucosal resurfacing in insulin resistant women with polycystic ovary syndrome.
    Metabolism. 2021;125:154908.
    PubMed     Abstract available


    November 2021
  84. HJORTEBJERG R, Bojsen-Moller KN, Soeby M, Oxvig C, et al
    Metabolic improvement after gastric bypass correlates with changes in IGF-regulatory proteins stanniocalcin-2 and IGFBP-4.
    Metabolism. 2021;124:154886.
    PubMed     Abstract available


    September 2021
  85. KOUVARI M, Chrysohoou C, Skoumas J, Pitsavos C, et al
    The presence of NAFLD influences the transition of metabolically healthy to metabolically unhealthy obesity and the ten-year cardiovascular disease risk: a population-based cohort study.
    Metabolism. 2021 Sep 30:154893. doi: 10.1016/j.metabol.2021.154893.
    PubMed     Abstract available


  86. KIM NH, Kim KJ, Choi J, Kim SG, et al
    Metabolically unhealthy individuals, either with obesity or not, have a higher risk of critical coronavirus disease 2019 outcomes than metabolically healthy individuals without obesity.
    Metabolism. 2021 Sep 30:154894. doi: 10.1016/j.metabol.2021.154894.
    PubMed     Abstract available


  87. PEI Z, Liu Y, Liu S, Jin W, et al
    FUNDC1 insufficiency sensitizes high fat diet intake-induced cardiac remodeling and contractile anomaly through ACSL4-mediated ferroptosis.
    Metabolism. 2021;122:154840.
    PubMed     Abstract available


    August 2021
  88. ZHU Y, Kim SQ, Zhang Y, Liu Q, et al
    Pharmacological inhibition of acyl-coenzyme A:cholesterol acyltransferase alleviates obesity and insulin resistance in diet-induced obese mice by regulating food intake.
    Metabolism. 2021 Aug 6:154861. doi: 10.1016/j.metabol.2021.154861.
    PubMed     Abstract available


  89. LANDRY T, Shookster D, Huang H
    Circulating alpha-klotho regulates metabolism via distinct central and peripheral mechanisms.
    Metabolism. 2021;121:154819.
    PubMed     Abstract available


    July 2021
  90. VAN GALEN KA, Booij J, Schrantee A, Adriaanse SM, et al
    The response to prolonged fasting in hypothalamic serotonin transporter availability is blunted in obesity.
    Metabolism. 2021 Jul 28:154839. doi: 10.1016/j.metabol.2021.154839.
    PubMed     Abstract available


    June 2021
  91. WANG Y, Xu J, Wang Y, Hou H, et al
    Obesity and COVID-19 mortality.
    Metabolism. 2021 Jun 22:154820. doi: 10.1016/j.metabol.2021.154820.
    PubMed    


  92. CLEMENTE-OLIVO MP, Habibe JJ, Vos M, Ottenhoff R, et al
    Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity.
    Metabolism. 2021 Jun 10:154815. doi: 10.1016/j.metabol.2021.154815.
    PubMed     Abstract available


  93. PICHE ME, Clavel MA, Auclair A, Rodriguez-Flores M, et al
    Early benefits of bariatric surgery on subclinical cardiac function: Contribution of visceral fat mobilization.
    Metabolism. 2021;119:154773.
    PubMed     Abstract available


  94. ZHANG Z, Lin T, Meng Y, Hu M, et al
    FOS/GOS attenuates high-fat diet induced bone loss via reversing microbiota dysbiosis, high intestinal permeability and systemic inflammation in mice.
    Metabolism. 2021;119:154767.
    PubMed     Abstract available


    May 2021
  95. FREUER D, Linseisen J, Meisinger C
    Impact of body composition on COVID-19 susceptibility and severity: A two-sample multivariable Mendelian randomization study.
    Metabolism. 2021;118:154732.
    PubMed     Abstract available


  96. HARRIS DA, Subramaniam R, Brenner T, Tavakkoli A, et al
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