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Malignant Melanoma |
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Elevated Lactic Acid Levels in the Aqueous Humor May Be an Indicator of Uveal
Melanoma.
Am J Ophthalmol. 2025 Sep 11:S0002-9394(25)00485.
PubMed
Abstract available
ASO Author Reflections: Recurrence Patterns and Survival Outcomes in Clinical
Stage IIB/IIC Melanoma: Can We Stratify Patients for Consideration of Neoadjuvant
Immunotherapy?
Ann Surg Oncol. 2025 Sep 17. doi: 10.1245/s10434-025-18373.
PubMed
ASO Visual Abstract: Accuracy of PET-CT to Assess the Extent of Nodal Disease in
Patients with Clinical Stage III Melanoma Following Neoadjuvant Treatment.
Ann Surg Oncol. 2025 Sep 16. doi: 10.1245/s10434-025-18370.
PubMed
Inhibition of anti-apoptotic BCL2 overcomes adaptive resistance to co-targeting
of the protein kinase FAK and MEK in GNAQ-driven uveal melanoma.
J Biol Chem. 2025 Sep 11:110712. doi: 10.1016/j.jbc.2025.110712.
PubMed
Abstract available
NR2F1 and mTORC1 provide the bridge between melanoma dormancy and therapeutic
resistance.
J Clin Invest. 2025;135:e197764.
PubMed
Abstract available
Elevated NR2F1 underlies the persistence of invasive disease after treatment of
BRAF-mutant melanoma.
J Clin Invest. 2025;135:e178446.
PubMed
Abstract available
cGAS activation converges with intracellular acidification to promote STING
aggregation and pyroptosis in tumor models.
J Clin Invest. 2025;135:e188872.
PubMed
Abstract available
Next-Generation Oncolytic Viruses to Overcome Resistance to Anti-PD-1 Therapy in
Melanoma.
J Clin Oncol. 2025 Sep 15:JCO2501683. doi: 10.1200/JCO-25-01683.
PubMed
Hexokinase 2 is an RNA-binding protein that regulates mRNA translation
independently of glycolysis and induces melanoma cell proliferation.
PLoS Biol. 2025;23:e3003364.
PubMed
Abstract available
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