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  Malaria

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Articles published in J Biol Chem

Retrieve available abstracts of 22 articles:
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Single Articles


    January 2024
  1. CHUNG Z, Lin J, Wirjanata G, Dziekan JM, et al
    Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848.
    J Biol Chem. 2024;300:105586.
    PubMed     Abstract available


    September 2023
  2. VAN NIEKERK DD, du Toit F, Green K, Palm D, et al
    A detailed kinetic model of glycolysis in Plasmodium falciparum-infected red blood cells for antimalarial drug target identification.
    J Biol Chem. 2023;299:105111.
    PubMed     Abstract available


    May 2023
  3. GODIN MJ, Sebastian A, Albert I, Lindner SE, et al
    Long-Read Genome Assembly and Gene Model Annotations for the Rodent Malaria Parasite Plasmodium yoelii 17XNL.
    J Biol Chem. 2023 May 27:104871. doi: 10.1016/j.jbc.2023.104871.
    PubMed     Abstract available


  4. RAMELOW J, Keleta Y, Niu G, Wang X, et al
    Plasmodium parasitophorous vacuole membrane protein Pfs16 promotes malaria transmission by silencing mosquito immunity.
    J Biol Chem. 2023 May 15:104824. doi: 10.1016/j.jbc.2023.104824.
    PubMed     Abstract available


  5. CHOI JY, Lopes L, Ben Mamoun C, Voelker DR, et al
    Maturation of the malarial phosphatidylserine decarboxylase is mediated by high affinity binding to anionic phospholipids.
    J Biol Chem. 2023;299:104659.
    PubMed     Abstract available


    September 2022
  6. ALDER A, Wilcke L, Pietsch E, von Thien H, et al
    Functional inactivation of Plasmodium falciparum glycogen synthase kinase GSK3 modulates erythrocyte invasion and blocks gametocyte maturation.
    J Biol Chem. 2022;298:102360.
    PubMed     Abstract available


  7. POLINO AJ, Miller JJ, Bhakat S, Mukherjee S, et al
    The nepenthesin insert in the Plasmodium falciparum aspartic protease plasmepsin V is necessary for enzyme function.
    J Biol Chem. 2022;298:102355.
    PubMed     Abstract available


  8. KUMAR H, Jimah JR, Misal SA, Salinas ND, et al
    Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration.
    J Biol Chem. 2022;298:102241.
    PubMed     Abstract available


    May 2022
  9. RAJARAM K, Tewari SG, Wallqvist A, Prigge ST, et al
    Metabolic changes accompanying the loss of fumarate hydratase and malate-quinone oxidoreductase in the asexual blood stage of Plasmodium falciparum.
    J Biol Chem. 2022;298:101897.
    PubMed     Abstract available


    April 2022
  10. SMITH LB, Duge E, Valenzuela-Leon PC, Brooks S, et al
    Novel salivary anti-hemostatic activities of long-form D7 proteins from the malaria vector Anopheles gambiae facilitate hematophagy.
    J Biol Chem. 2022 Apr 20:101971. doi: 10.1016/j.jbc.2022.101971.
    PubMed     Abstract available


    March 2022
  11. TEHLAN A, Bhowmick K, Kumar A, Subbarao N, et al
    The tetrameric structure of Plasmodium falciparum phosphoglycerate mutase is critical for optimal enzymatic activity.
    J Biol Chem. 2022;298:101713.
    PubMed     Abstract available


  12. BYUN JA, VanSchouwen B, Huang J, Baryar U, et al
    Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G.
    J Biol Chem. 2022;298:101691.
    PubMed     Abstract available


    February 2022
  13. LU J, Chu R, Yin Y, Yu H, et al
    Glycosylphosphatidylinositol-anchored micronemal antigen (GAMA) interacts with the band 3 receptor to promote erythrocyte invasion by malaria parasites.
    J Biol Chem. 2022 Feb 21:101765. doi: 10.1016/j.jbc.2022.101765.
    PubMed     Abstract available


    December 2021
  14. FRASSE PM, Miller JJ, Polino AJ, Soleimani E, et al
    Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites.
    J Biol Chem. 2021 Dec 29:101550. doi: 10.1016/j.jbc.2021.101550.
    PubMed     Abstract available


  15. SPLIID CB, Toledo AG, Sanderson P, Mao Y, et al
    The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility.
    J Biol Chem. 2021;297:101391.
    PubMed     Abstract available


    March 2021
  16. WU X, Brombacher F, Chroneos ZC, Norbury CC, et al
    IL-4Ralpha signaling by CD8alpha(+) dendritic cells contributes to cerebral malaria by enhancing inflammatory, Th1, and cytotoxic CD8(+) T cell responses.
    J Biol Chem. 2021 Mar 30:100615. doi: 10.1016/j.jbc.2021.100615.
    PubMed     Abstract available


    January 2021
  17. JABEENA CA, Govindaraju G, Rawat M, Gopi S, et al
    Dynamic association of the H3K64 trimethylation mark with genes encoding exported proteins in Plasmodium falciparum.
    J Biol Chem. 2021;296:100614.
    PubMed     Abstract available


  18. MINNOW YVT, Harijan RK, Schramm VL
    A resistant mutant of Plasmodium falciparum purine nucleoside phosphorylase uses wild-type neighbors to maintain parasite survival.
    J Biol Chem. 2021;296:100342.
    PubMed     Abstract available


  19. MA W, Balta VA, West R, Newlin KN, et al
    A second mechanism employed by artemisinins to suppress Plasmodium falciparum hinges on inhibition of hematin crystallization.
    J Biol Chem. 2021;296:100123.
    PubMed     Abstract available


    December 2020
  20. BEWLEY MC, Gautam L, Jagadeeshaprasad MG, Gowda DC, et al
    Molecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding.
    J Biol Chem. 2020;295:18589-18603.
    PubMed     Abstract available


    October 2020
  21. BEWLEY MC, Gautam L, Jagadeeshaprasad MG, Gowda DC, et al
    Molecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding.
    J Biol Chem. 2020 Oct 29. pii: RA120.014676. doi: 10.1074/jbc.RA120.014676.
    PubMed     Abstract available


    May 2020
  22. LING L, Mulaka M, Munro J, Dass S, et al
    Genetic ablation of the mitoribosome in the malaria parasite Plasmodium falciparum sensitizes it to antimalarials that target mitochondrial functions.
    J Biol Chem. 2020;295:7235-7248.
    PubMed     Abstract available


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