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  Malignant Lymphoma

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Articles published in Proc Natl Acad Sci U S A

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    June 2021
  1. FANGAZIO M, Ladewig E, Gomez K, Garcia-Ibanez L, et al
    Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  2. PATIL K, Jordan EJ, Park JH, Suresh K, et al
    Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2020
  3. HOLMES DL, Vogt DT, Lagunoff M
    A CRISPR-Cas9 screen identifies mitochondrial translation as an essential process in latent KSHV infection of human endothelial cells.
    Proc Natl Acad Sci U S A. 2020;117:28384-28392.
    PubMed     Abstract available


  4. WANG Q, Lin YY, Zhang B, Wu J, et al
    A mosaic analysis system with Cre or Tomato expression in the mouse.
    Proc Natl Acad Sci U S A. 2020;117:28212-28220.
    PubMed     Abstract available


  5. SONG Z, Wei W, Xiao W, Al-Saleem ED, et al
    Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma.
    Proc Natl Acad Sci U S A. 2020 Nov 2. pii: 2014470117.
    PubMed     Abstract available


    August 2020
  6. PARK A, Oh S, Jung KL, Choi UY, et al
    Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional MYC superenhancers and enhancer RNAs.
    Proc Natl Acad Sci U S A. 2020 Aug 18. pii: 1922216117.
    PubMed     Abstract available


    June 2020
  7. SOMMERMANN T, Yasuda T, Ronen J, Wirtz T, et al
    Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
    Proc Natl Acad Sci U S A. 2020;117:14421-14432.
    PubMed     Abstract available


  8. HIGUCHI Y, Yasunaga JI, Mitagami Y, Tsukamoto H, et al
    HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling.
    Proc Natl Acad Sci U S A. 2020;117:13740-13749.
    PubMed     Abstract available


    May 2020
  9. NAGASAKA M, Yamagishi M, Yagishita N, Araya N, et al
    Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis.
    Proc Natl Acad Sci U S A. 2020 May 11. pii: 1920346117.
    PubMed     Abstract available


    March 2020
  10. CHOI J, Phelan JD, Wright GW, Haupl B, et al
    Regulation of B cell receptor-dependent NF-kappaB signaling by the tumor suppressor KLHL14.
    Proc Natl Acad Sci U S A. 2020;117:6092-6102.
    PubMed     Abstract available


  11. LION M, Muhire B, Namiki Y, Tolstorukov MY, et al
    Alterations in chromatin at antigen receptor loci define lineage progression during B lymphopoiesis.
    Proc Natl Acad Sci U S A. 2020;117:5453-5462.
    PubMed     Abstract available


    February 2020
  12. BRUNO PM, Lu M, Dennis KA, Inam H, et al
    The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning.
    Proc Natl Acad Sci U S A. 2020 Feb 10. pii: 1921649117.
    PubMed     Abstract available


    January 2020
  13. LUCHTEL RA, Bhagat T, Pradhan K, Jacobs WR Jr, et al
    High-dose ascorbic acid synergizes with anti-PD1 in a lymphoma mouse model.
    Proc Natl Acad Sci U S A. 2020 Jan 7. pii: 1908158117.
    PubMed     Abstract available


    November 2019
  14. MULAZZANI M, Frassle SP, von Mucke-Heim I, Langer S, et al
    Long-term in vivo microscopy of CAR T cell dynamics during eradication of CNS lymphoma in mice.
    Proc Natl Acad Sci U S A. 2019 Nov 11. pii: 1903854116.
    PubMed     Abstract available


    August 2019
  15. LOPEZ-MOYADO IF, Tsagaratou A, Yuita H, Seo H, et al
    Paradoxical association of TET loss of function with genome-wide DNA hypomethylation.
    Proc Natl Acad Sci U S A. 2019;116:16933-16942.
    PubMed     Abstract available


  16. FAURE A, Hayes M, Sugden B
    How Kaposi's sarcoma-associated herpesvirus stably transforms peripheral B cells towards lymphomagenesis.
    Proc Natl Acad Sci U S A. 2019;116:16519-16528.
    PubMed     Abstract available


  17. SCUOPPO C, Wang J, Persaud M, Mittan SK, et al
    Repurposing dasatinib for diffuse large B cell lymphoma.
    Proc Natl Acad Sci U S A. 2019 Aug 5. pii: 1905239116.
    PubMed     Abstract available


    July 2019
  18. WONG JP, Stuhlmiller TJ, Giffin LC, Lin C, et al
    Kinome profiling of non-Hodgkin lymphoma identifies Tyro3 as a therapeutic target in primary effusion lymphoma.
    Proc Natl Acad Sci U S A. 2019 Jul 25. pii: 1903991116.
    PubMed     Abstract available


    May 2019
  19. SANG P, Zhang M, Shi Y, Li C, et al
    Inhibition of beta-catenin/B cell lymphoma 9 protein-protein interaction using alpha-helix-mimicking sulfono-gamma-AApeptide inhibitors.
    Proc Natl Acad Sci U S A. 2019 May 14. pii: 1819663116.
    PubMed     Abstract available


    December 2018
  20. ZELLA D, Curreli S, Benedetti F, Krishnan S, et al
    Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperon protein, has broad oncogenic properties.
    Proc Natl Acad Sci U S A. 2018;115:E12005-E12014.
    PubMed     Abstract available


    November 2018
  21. BIGI R, Landis JT, An H, Caro-Vegas C, et al
    Epstein-Barr virus enhances genome maintenance of Kaposi sarcoma-associated herpesvirus.
    Proc Natl Acad Sci U S A. 2018;115:E11379-E11387.
    PubMed     Abstract available


  22. TAGAWA T, Gao S, Koparde VN, Gonzalez M, et al
    Discovery of Kaposi's sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA.
    Proc Natl Acad Sci U S A. 2018 Nov 19. pii: 1816183115.
    PubMed     Abstract available


  23. LIU Y, Mondello P, Erazo T, Tannan NB, et al
    NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death.
    Proc Natl Acad Sci U S A. 2018 Nov 7. pii: 1806928115.
    PubMed     Abstract available


    September 2018
  24. TOPTAN T, Abere B, Nalesnik MA, Swerdlow SH, et al
    Circular DNA tumor viruses make circular RNAs.
    Proc Natl Acad Sci U S A. 2018;115:E8737-E8745.
    PubMed     Abstract available


    April 2018
  25. HUANG Q, Chen L, Yang L, Xie X, et al
    MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis.
    Proc Natl Acad Sci U S A. 2018;115:E3368-E3377.
    PubMed     Abstract available


    March 2018
  26. POLLOCK SB, Hu A, Mou Y, Martinko AJ, et al
    Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.
    Proc Natl Acad Sci U S A. 2018;115:2836-2841.
    PubMed     Abstract available


    January 2018
  27. TAN Q, Brunetti L, Rousseaux MWC, Lu HC, et al
    Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
    Proc Natl Acad Sci U S A. 2018 Jan 30. pii: 1716452115.
    PubMed     Abstract available


  28. FADEEV A, Mendoza-Garcia P, Irion U, Guan J, et al
    ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells.
    Proc Natl Acad Sci U S A. 2018;115:E630-E638.
    PubMed     Abstract available


  29. CHOI IK, Wang Z, Ke Q, Hong M, et al
    Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
    Proc Natl Acad Sci U S A. 2018;115:E686-E695.
    PubMed     Abstract available


  30. LU L, Zhu F, Zhang M, Li Y, et al
    Gene regulation and suppression of type I interferon signaling by STAT3 in diffuse large B cell lymphoma.
    Proc Natl Acad Sci U S A. 2018 Jan 2. pii: 1715118115.
    PubMed     Abstract available


    October 2017
  31. DUCKER GS, Ghergurovich JM, Mainolfi N, Suri V, et al
    Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
    Proc Natl Acad Sci U S A. 2017;114:11404-11409.
    PubMed     Abstract available


    August 2017
  32. TANG J, Salloum D, Carney B, Brand C, et al
    Targeted PET imaging strategy to differentiate malignant from inflamed lymph nodes in diffuse large B-cell lymphoma.
    Proc Natl Acad Sci U S A. 2017 Aug 21. pii: 201705013.
    PubMed     Abstract available


    April 2017
  33. FISH K, Longnecker R
    EBV germinates lymphoma from the germinal center in a battle with T and NK cells.
    Proc Natl Acad Sci U S A. 2017 Apr 25. pii: 201704102.
    PubMed    


    March 2017
  34. CHEN J, Zhang Y, Petrus MN, Xiao W, et al
    Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.
    Proc Natl Acad Sci U S A. 2017 Mar 29. pii: 201700682.
    PubMed     Abstract available


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