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  Lung Cancer

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Articles published in Cancer Res

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Single Articles


    February 2026
  1. WANG M, Song Z, Yuan H, Liu C, et al
    Protumor Macrophage Polarization Mediated by BMP2/4-ACVR1 Signaling Orchestrates an Immunosuppressive Microenvironment during Tumor Initiation.
    Cancer Res. 2026;86:954-971.
    PubMed     Abstract available


  2. JUNTTILA MR, Repellin CE, Salaniwal S, Warne R, et al
    Enozertinib Is a Selective, Brain-Penetrant EGFR Inhibitor for Treating Non-Small Cell Lung Cancers with EGFR Exon 20 and Atypical Mutations.
    Cancer Res. 2026;86:759-772.
    PubMed     Abstract available


    January 2026
  3. QI L, Dang G, Ling X, Miao Y, et al
    Targeting LRRC15 in Cancer-Associated Fibroblasts Modifies the Extracellular Matrix and Enhances Tumor Immune Responses to Suppress Lung Cancer Progression.
    Cancer Res. 2026 Jan 27. doi: 10.1158/0008-5472.CAN-25-2871.
    PubMed     Abstract available


  4. STERN YE, Ghosh P, Peroza J, Solanki HS, et al
    Targeting CDK12/13 Drives Mitotic Arrest to Overcome Resistance to KRASG12C Inhibitors.
    Cancer Res. 2026;86:485-502.
    PubMed     Abstract available


  5. MUCCIOLO G, Biffi G
    Lung Metastases in Pancreatic Cancer: Timing Their First Breath.
    Cancer Res. 2026;86:7-9.
    PubMed     Abstract available


  6. LASSE OPSAHL EL, Espinoza CE, Olivei AC, Okoye JO, et al
    Fibroblast STAT3 Activation Drives Organ-Specific Premetastatic Niche Formation.
    Cancer Res. 2026;86:22-39.
    PubMed     Abstract available


  7. HULSE M, Wang M, Xu C, Carter J, et al
    PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4-Mutated Cancers.
    Cancer Res. 2026;86:213-235.
    PubMed     Abstract available


  8. ASSIE JB, Meiller C, Stern E, Lasvergnas J, et al
    Pharmacogenomic Characterization of a Large Cohort of Patient-Derived Cell Lines Identifies Therapeutic Strategies for Pleural Mesothelioma.
    Cancer Res. 2026;86:196-212.
    PubMed     Abstract available


    December 2025
  9. PRABHAKARAN S, Gatenbee CD, Robertson-Tessi M, Gahramanli Ozturk Z, et al
    Distinct Tumor-Immune Ecologies in Lung Cancer Patients Predict Progression and Define a Clinical Biomarker of Therapy Response.
    Cancer Res. 2025 Dec 19. doi: 10.1158/0008-5472.CAN-25-1594.
    PubMed     Abstract available


  10. BOETTIGER K, Kovacs I, Horvath L, Ernhofer B, et al
    Small Cell Lung Cancer Classification: Unraveling Heterogeneity to Enable Personalized Treatments.
    Cancer Res. 2025 Dec 18. doi: 10.1158/0008-5472.CAN-25-1483.
    PubMed     Abstract available


  11. LUO H, Guo W, Luan X, Yue T, et al
    Large-Scale T-cell Receptor Repertoire Profiling Unveils Tumor-Specific Signals for Diagnosing Indeterminate Pulmonary Nodules.
    Cancer Res. 2025;85:5141-5160.
    PubMed     Abstract available


  12. HAYKAL T, Yang R, Tohme C, He Z, et al
    Surgery-Induced Neutrophil Extracellular Traps Promote Tumor Metastasis by Reprogramming Cancer Cell Lipid Metabolism.
    Cancer Res. 2025;85:4995-5014.
    PubMed     Abstract available


  13. LIU T, Huang S, Li Z, Li J, et al
    Transfer of Damaged Mitochondria from Cancer Cells to Cancer-Associated Fibroblasts Promotes Tyrosine Kinase Inhibitor Tolerance in EGFR-Mutant Lung Cancer.
    Cancer Res. 2025 Dec 2. doi: 10.1158/0008-5472.CAN-25-0433.
    PubMed     Abstract available


  14. YASSEEN BA, DeNicola GM
    Can't KEEP Up: UXS1 Dependency Exposes a Pyrimidine Vulnerability in KEAP1-Mutant Lung Cancer.
    Cancer Res. 2025;85:4582-4584.
    PubMed     Abstract available


    November 2025
  15. PAN L, Luo J, Nie C, Fan S, et al
    A Deep Learning Framework Integrating Tumor Microenvironmental Features Accurately Predicts Multiple Driver Gene Mutations in Lung Cancer Pathology Images.
    Cancer Res. 2025 Nov 25. doi: 10.1158/0008-5472.CAN-25-0582.
    PubMed     Abstract available


  16. REINECKE JB, Jimenez Garcia L, Saraf AJ, Hinckley J, et al
    Metastasis-Initiating Osteosarcoma Subpopulations Establish Paracrine Interactions with Lung and Tumor Cells to Create a Metastatic Niche.
    Cancer Res. 2025;85:4341-4358.
    PubMed     Abstract available


    October 2025
  17. SOLANKI HS, Shah H, Imbody D, Desai B, et al
    RAS-GTP Inhibition Overcomes Acquired Resistance to KRASG12C Inhibitors Mediated by Oncogenic and Wildtype RAS Activation in Non-Small Cell Lung Cancer.
    Cancer Res. 2025 Oct 30. doi: 10.1158/0008-5472.CAN-25-0600.
    PubMed     Abstract available


  18. ZHANG S, Wang S, Wang Y, Zhou T, et al
    PRMT3 Drives IDO1-Dependent Radioresistance and Immunosuppression by Promoting Kynurenine Metabolism in Non-Small Cell Lung Cancer.
    Cancer Res. 2025 Oct 23. doi: 10.1158/0008-5472.CAN-24-4162.
    PubMed     Abstract available


  19. LIN DC, Shen K
    Precision Epigenetic Reprogramming: CoREST Inhibition Sensitizes STK11-Mutant Tumors to Immune Checkpoint Blockade Therapy.
    Cancer Res. 2025;85:3821-3822.
    PubMed     Abstract available


  20. AHRONIAN LG, Sahu S, Zhang M, Patel AS, et al
    TNG260 Is a Small-Molecule CoREST Inhibitor That Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy.
    Cancer Res. 2025;85:3966-3982.
    PubMed     Abstract available


    September 2025
  21. PAN T, Zhu J, Wang X, Tang D, et al
    MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-25-0021.
    PubMed     Abstract available


  22. LIU P, Zheng J, Ma W, Lu J, et al
    Stress Promotes Lung Metastasis in Breast Cancer by Altering Neutrophil Differentiation.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-25-1763.
    PubMed     Abstract available


  23. GEBRU MT, Hoffman TE, Boudreau A, Vu N, et al
    Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer.
    Cancer Res. 2025 Sep 18. doi: 10.1158/0008-5472.CAN-24-4887.
    PubMed     Abstract available


  24. KNOLL N, Masser S, Bordas B, Ebright RY, et al
    CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-Deleted Cancer.
    Cancer Res. 2025;85:3518-3539.
    PubMed     Abstract available


  25. CAO G, Ma L, Wang X, Li G, et al
    Interaction and Reciprocal Stabilization of H3.3 and PARP1 Promotes DNA Damage Repair and Tumor Progression in Small Cell Lung Cancer.
    Cancer Res. 2025 Sep 12. doi: 10.1158/0008-5472.CAN-24-4245.
    PubMed     Abstract available


  26. AVELLINO A, Jiang X, Lee M, Yu J, et al
    An Olive Oil-Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer.
    Cancer Res. 2025 Sep 5. doi: 10.1158/0008-5472.CAN-25-0822.
    PubMed     Abstract available


  27. WU CP, Vaishnavi A
    Another Slice of the Pie Uncovered: RIT1M90I Is an Actionable Driver in Non-Small Cell Lung Cancer.
    Cancer Res. 2025;85:3186-3188.
    PubMed     Abstract available


  28. MOZZARELLI AM, Cuevas-Navarro A, Shuldiner EG, Vega M, et al
    RIT1 Drives Oncogenic Transformation and Is an Actionable Target in Lung Adenocarcinoma.
    Cancer Res. 2025;85:3196-3206.
    PubMed     Abstract available


  29. DIMARCO AV, Ravichandran M, Lau J, Lima A, et al
    RIT1M90I Is a Driver of Lung Adenocarcinoma Tumorigenesis and Resistance to Targeted Therapy.
    Cancer Res. 2025;85:3207-3218.
    PubMed     Abstract available


    August 2025
  30. DING W, Zhu J, Mo J, Ouyang S, et al
    Neuropeptide Precursor VGF Promotes Neuroendocrine Differentiation and Cancer-Associated Fibroblast Activation in Small Cell Lung Cancer.
    Cancer Res. 2025 Aug 26. doi: 10.1158/0008-5472.CAN-25-0405.
    PubMed     Abstract available


  31. ZHAO J, Zhang W, Zeng Y, Lu D, et al
    Targeting ATP7A-Dependent Copper Metabolic Homeostasis Induces Cuproptosis and Suppresses the Progression of Mutant KRAS-Driven Lung Cancer.
    Cancer Res. 2025 Aug 21. doi: 10.1158/0008-5472.CAN-24-2558.
    PubMed     Abstract available


  32. QIN N, Wang Z, Xu X, Xie Y, et al
    Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients.
    Cancer Res. 2025;85:2905-2920.
    PubMed     Abstract available


    July 2025
  33. REDIN E, Otegui N, Santos M, Leon S, et al
    Dasatinib Remodels the Tumor Microenvironment and Sensitizes Small Cell Lung Cancer to Immunotherapy.
    Cancer Res. 2025 Jul 25. doi: 10.1158/0008-5472.CAN-24-2772.
    PubMed     Abstract available


  34. SEN U, Coleman C, Gandhi N, Jethalia V, et al
    SCD1 Inhibition Blocks the AKT-NRF2-SLC7A11 Pathway to Induce Lipid Metabolism Remodeling and Ferroptosis Priming in Lung Adenocarcinoma.
    Cancer Res. 2025;85:2485-2503.
    PubMed     Abstract available


    June 2025
  35. WANG Y, Meraz IM, Qudratullah M, Kotagiri S, et al
    Mutation of SMARCA4 Induces Cancer Cell-Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy.
    Cancer Res. 2025;85:1997-2013.
    PubMed     Abstract available


    May 2025
  36. TONG X, Lin G, Ji H
    "Dr. Jekyll and Mr. Hyde": AT2 Cells in Lung Regeneration and Tumor Development.
    Cancer Res. 2025;85:1753-1754.
    PubMed     Abstract available


  37. WANG K, Li J, Zhang H, Ma H, et al
    Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression.
    Cancer Res. 2025 May 14. doi: 10.1158/0008-5472.CAN-24-3525.
    PubMed     Abstract available


  38. QU T, Song L, Xu J, Lu X, et al
    MYLK-AS1 Enhances Glutamine Metabolism to Promote EGFR Inhibitor Resistance in Non-Small Cell Lung Cancer.
    Cancer Res. 2025 May 14. doi: 10.1158/0008-5472.CAN-23-3748.
    PubMed     Abstract available


  39. THOMAS-JARDIN S, Suresh S, Arce A, Novaresi N, et al
    The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer.
    Cancer Res. 2025 May 6. doi: 10.1158/0008-5472.CAN-24-3844.
    PubMed     Abstract available


  40. PAPARGYRIOU A, Reichert M
    The Biology in the Pattern: Metastatic Organotropism and Clinical Outcome Depend on DNA Damage Response and Immune Interactions in Pancreatic Cancer.
    Cancer Res. 2025;85:1571-1573.
    PubMed     Abstract available


  41. HAN J, Du J, Li X, Zhou Q, et al
    The Glycosyltransferase XYLT1 Activates NF-kappaB Signaling to Promote Metastasis of Early-Stage Lung Adenocarcinoma.
    Cancer Res. 2025;85:1628-1643.
    PubMed     Abstract available


    April 2025
  42. CAI L, Wu F, Zhou Q, Gao Y, et al
    The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models.
    Cancer Res. 2025 Apr 29:OF1-OF15. doi: 10.1158/0008-5472.CAN-24-1607.
    PubMed     Abstract available


  43. LIU C, Du H, Yu G, Qi J, et al
    Chronic Stress Stimulates Protumor Macrophage Polarization to Propel Lung Cancer Progression.
    Cancer Res. 2025 Apr 9. doi: 10.1158/0008-5472.CAN-24-3481.
    PubMed     Abstract available


  44. EIGENBROOD J, Wong N, Mallory P, Pereira JS, et al
    Spatial Profiling Identifies Regionally Distinct Microenvironments and Targetable Immunosuppressive Mechanisms in Pediatric Osteosarcoma Pulmonary Metastases.
    Cancer Res. 2025 Apr 2. doi: 10.1158/0008-5472.CAN-24-3723.
    PubMed     Abstract available


    March 2025
  45. LEE TR, Ahn JM, Lee J, Kim D, et al
    Integrating Plasma Cell-Free DNA Fragment End Motif and Size with Genomic Features Enables Lung Cancer Detection.
    Cancer Res. 2025 Mar 26:OF1-OF12. doi: 10.1158/0008-5472.CAN-24-1517.
    PubMed     Abstract available


  46. SCORTEGAGNA M, Murad R, Bina P, Feng Y, et al
    Age-Associated Modulation of TREM1/2-Expressing Macrophages Promotes Melanoma Progression and Metastasis.
    Cancer Res. 2025 Mar 24. doi: 10.1158/0008-5472.CAN-24-4317.
    PubMed     Abstract available


  47. SOS ML, Koker M, Weir BA, Heynck S, et al
    Editor's Note: PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR.
    Cancer Res. 2025;85:1003.
    PubMed    


    February 2025
  48. BADO IL
    Deterministic Role of FOXF2 in Organ-Specific Macrometastasis Transition.
    Cancer Res. 2025;85:639-641.
    PubMed     Abstract available


  49. CHEN YC, Hsu CL, Wang HM, Wu SG, et al
    Multiomics Analysis Reveals Molecular Changes during Early Progression of Precancerous Lesions to Lung Adenocarcinoma in Never-Smokers.
    Cancer Res. 2025;85:602-617.
    PubMed     Abstract available


  50. ZHANG Y, Song X, Feng Y, Qian Y, et al
    The circRNA cEMSY Induces Immunogenic Cell Death and Boosts Immunotherapy Efficacy in Lung Adenocarcinoma.
    Cancer Res. 2025;85:497-514.
    PubMed     Abstract available


    January 2025
  51. DALEY BR, Sealover NE, Finniff BA, Hughes JM, et al
    SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma.
    Cancer Res. 2025;85:118-133.
    PubMed     Abstract available


    December 2024
  52. CHEN SY, He PL, Lu LY, Lin MC, et al
    ST6GAL1-Mediated Sialylation of PECAM-1 Promotes a Transcellular Diapedesis-Like Process that Directs Lung Tropism of Metastatic Breast Cancer.
    Cancer Res. 2024 Dec 30. doi: 10.1158/0008-5472.CAN-24-1550.
    PubMed     Abstract available


  53. SAAL J, Klumper N, Holzel M
    C-Reactive Protein Facilitates Premetastatic Niche Formation in the Lungs.
    Cancer Res. 2024;84:4121-4123.
    PubMed     Abstract available


  54. FENG JR, Li X, Han C, Chang Y, et al
    C-Reactive Protein Induces Immunosuppression by Activating FcgammaR2B in Pulmonary Macrophages to Promote Lung Metastasis.
    Cancer Res. 2024;84:4184-4198.
    PubMed     Abstract available


    November 2024
  55. JIANG WJ, Zhou TH, Huang HJ, Li LS, et al
    Breast Cancer Subtype-Specific Organotropism is Dictated by FOXF2-Regulated Metastatic Dormancy and Recovery.
    Cancer Res. 2024 Nov 26. doi: 10.1158/0008-5472.CAN-24-0479.
    PubMed     Abstract available


  56. WANG S, Lai JC, Li Y, Tang C, et al
    Loss of CDKN2A Enhances the Efficacy of Immunotherapy in EGFR Mutant Non-Small Cell Lung Cancer.
    Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-1817.
    PubMed     Abstract available


    October 2024
  57. XU H, Yue M, Zhou R, Wang P, et al
    A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis.
    Cancer Res. 2024;84:3173-3188.
    PubMed     Abstract available


    September 2024
  58. MAY L, Hu B, Jerajani P, Jagdeesh A, et al
    The Innate Immune System and TRAIL-BCL-XL Axis Mediate a Sex Bias in Lung Cancer and Confer a Therapeutic Vulnerability in Females.
    Cancer Res. 2024 Sep 23. doi: 10.1158/0008-5472.CAN-24-0585.
    PubMed     Abstract available


  59. SMITH MR, Dixon CB, Wang Y, Liu Y, et al
    Targeting NTRK1 Enhances Immune Checkpoint Inhibitor Efficacy in NTRK1 Wild-type Non-Small Cell Lung Cancer.
    Cancer Res. 2024 Sep 9. doi: 10.1158/0008-5472.CAN-24-0658.
    PubMed     Abstract available


  60. CONNER SJ, Borges HB, Guarin JR, Gerton TJ, et al
    Obesity Induces Temporally Regulated Alterations in the Extracellular Matrix That Drive Breast Tumor Invasion and Metastasis.
    Cancer Res. 2024;84:2761-2775.
    PubMed     Abstract available


    August 2024
  61. KOO J, Seong CS, Parker RE, Herrera A, et al
    Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer.
    Cancer Res. 2024 Aug 29. doi: 10.1158/0008-5472.CAN-23-2631.
    PubMed     Abstract available


  62. LIN W, Wang N, Wu S, Diao M, et al
    NUAK1-Mediated Phosphorylation of NADK Mitigates ROS Accumulation to Promote Osimertinib Resistance in Non-Small Cell Lung Carcinoma.
    Cancer Res. 2024 Aug 19. doi: 10.1158/0008-5472.CAN-24-0249.
    PubMed     Abstract available


  63. ZHANG C, Zhou L, Zhang M, Du Y, et al
    H3K18 Lactylation Potentiates Immune Escape of Non-Small Cell Lung Cancer.
    Cancer Res. 2024 Aug 13. doi: 10.1158/0008-5472.CAN-23-3513.
    PubMed     Abstract available


  64. FU M, Gao Q, Xiao M, Li RF, et al
    Extracellular Vesicles Containing circMYBL1 Induce CD44 in Adenoid Cystic Carcinoma Cells and Pulmonary Endothelial Cells to Promote Lung Metastasis.
    Cancer Res. 2024;84:2484-2500.
    PubMed     Abstract available


    July 2024
  65. WANG X, Qu Y, Xu Q, Jiang Z, et al
    NQO1 Triggers Neutrophil Recruitment and NET formation to Drive Lung Metastasis of Invasive Breast Cancer.
    Cancer Res. 2024 Jul 29. doi: 10.1158/0008-5472.CAN-24-0291.
    PubMed     Abstract available


  66. LI J, Luo L, He J, Yu J, et al
    A Virus-Inspired Inhalable Liponanogel Induces Potent Antitumor Immunity and Regression in Metastatic Lung Tumors.
    Cancer Res. 2024;84:2352-2363.
    PubMed     Abstract available


    June 2024
  67. OATMAN N, Gawali MV, Congrove S, Caceres R, et al
    A multimodal drug-diet-immunotherapy combination restrains melanoma progression and metastasis.
    Cancer Res. 2024 Jun 17. doi: 10.1158/0008-5472.CAN-23-1635.
    PubMed     Abstract available


  68. HUANG CY, Jiang N, Shen M, Lai GG, et al
    Oncogene-Driven Non-Small Cell Lung Cancers in Patients with a History of Smoking Lack Smoking-Induced Mutations.
    Cancer Res. 2024;84:2009-2020.
    PubMed     Abstract available


  69. HERZOG C, Jones A, Evans I, Raut JR, et al
    Cigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis.
    Cancer Res. 2024;84:1898-1914.
    PubMed     Abstract available


    May 2024
  70. RAINERO E
    Overcoming Nutrient Stress: Integrin alphavbeta3-Driven Metabolic Adaptation Supports Tumor Initiation.
    Cancer Res. 2024;84:1543-1545.
    PubMed     Abstract available


  71. PARK SJ, Ju S, Goh SH, Yoon BH, et al
    Proteogenomic Characterization Reveals Estrogen Signaling as a Target for Never-Smoker Lung Adenocarcinoma Patients without EGFR or ALK Alterations.
    Cancer Res. 2024;84:1491-1503.
    PubMed     Abstract available


  72. XIANG H, Pan Y, Sze MA, Wlodarska M, et al
    Single-Cell Analysis Identifies NOTCH3-Mediated Interactions between Stromal Cells That Promote Microenvironment Remodeling and Invasion in Lung Adenocarcinoma.
    Cancer Res. 2024;84:1410-1425.
    PubMed     Abstract available


    April 2024
  73. BOUMELHA J, de Castro A, Bah N, Cha H, et al
    CRISPR-Cas9 screening identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2627.
    PubMed     Abstract available


  74. RUMDE PH, Burns TF
    A Path to Persistence after EGFR Inhibition.
    Cancer Res. 2024;84:1188-1190.
    PubMed     Abstract available


  75. PETRONI G, Pillozzi S, Antonuzzo L
    Exploiting Tertiary Lymphoid Structures to Stimulate Antitumor Immunity and Improve Immunotherapy Efficacy.
    Cancer Res. 2024;84:1199-1209.
    PubMed     Abstract available


  76. LAU A, Blenis J, Burgos-Barragan G
    Decoding Serine Metabolism: Unveiling Novel Pathways for Evolving Cancer Therapies.
    Cancer Res. 2024;84:1191-1194.
    PubMed     Abstract available


  77. ZHU X, Fu Z, Dutchak K, Arabzadeh A, et al
    Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer.
    Cancer Res. 2024;84:1333-1351.
    PubMed     Abstract available


  78. NAM A, Jain S, Wu C, Campos A, et al
    Integrin alphavbeta3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity.
    Cancer Res. 2024 Apr 8:OF1-OF13. doi: 10.1158/0008-5472.CAN-23-2700.
    PubMed     Abstract available


  79. LIU Y, Murazzi I, Fuller AM, Pan H, et al
    Sarcoma Cells Secrete Hypoxia-Modified Collagen VI to Weaken the Lung Endothelial Barrier and Promote Metastasis.
    Cancer Res. 2024;84:977-993.
    PubMed     Abstract available


  80. XU Y, Deng C, Chen H, Song Y, et al
    Osteosarcoma Cells Secrete CXCL14 That Activates Integrin alpha11beta1 on Fibroblasts to Form a Lung Metastatic Niche.
    Cancer Res. 2024;84:994-1012.
    PubMed     Abstract available


    March 2024
  81. GAI X, Liu Y, Lan X, Chen L, et al
    Oncogenic KRAS induces arginine auxotrophy and confers a therapeutic vulnerability to SLC7A1 inhibition in non-small cell lung cancer.
    Cancer Res. 2024 Mar 19. doi: 10.1158/0008-5472.CAN-23-2095.
    PubMed     Abstract available


  82. WANG H, Zhang Y, Tian Y, Yang W, et al
    DNA-PK-Mediated Cytoplasmic DNA Sensing Stimulates Glycolysis to Promote Lung Squamous Cell Carcinoma Malignancy and Chemoresistance.
    Cancer Res. 2024;84:688-702.
    PubMed     Abstract available


    February 2024
  83. HU B, Wiesehofer M, de Miguel FJ, Liu Z, et al
    ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts.
    Cancer Res. 2024 Feb 15. doi: 10.1158/0008-5472.CAN-23-0438.
    PubMed     Abstract available


  84. ALEWINE C
    Macrophages Under the Influence of Tumor Mesothelin Weaken Host Defenses against Pancreatic Cancer Metastasis.
    Cancer Res. 2024;84:513-514.
    PubMed     Abstract available


  85. RIGAMONTI A, Viatore M, Polidori R, Rahal D, et al
    Integrating AI-powered digital pathology and imaging mass cytometry identifies key classifiers of tumor cells, stroma, and immune cells in non-small cell lung cancer.
    Cancer Res. 2024 Feb 5. doi: 10.1158/0008-5472.CAN-23-1698.
    PubMed     Abstract available


    January 2024
  86. MU M, Huang CX, Qu C, Li PL, et al
    Targeting ferroptosis-elicited inflammation suppresses hepatocellular carcinoma metastasis and enhances sorafenib efficacy.
    Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1796.
    PubMed     Abstract available


  87. SAGGESE P, Pandey A, Alcaraz M Jr, Fung E, et al
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma.
    Cancer Res. 2024;84:305-327.
    PubMed     Abstract available


    December 2023
  88. NIU X, Martinez L
    Harnessing p53 to Improve Immunotherapy for Lung Cancer Treatment.
    Cancer Res. 2023 Dec 21:OF1-OF2. doi: 10.1158/0008-5472.CAN-23-3929.
    PubMed     Abstract available


  89. DU M, Xin J, Zheng R, Yuan Q, et al
    CYP2A6 activity and cigarette consumption interact in smoking-related lung cancer susceptibility.
    Cancer Res. 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-0900.
    PubMed     Abstract available


  90. MUKHOPADHYAY S, Huang HY, Lin Z, Ranieri M, et al
    Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy.
    Cancer Res. 2023;83:4095-4111.
    PubMed     Abstract available


  91. NIU X, Martinez L
    Harnessing p53 to improve immunotherapy for lung cancer treatment.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-3929.
    PubMed     Abstract available


  92. XIA L, Liu JY, Yang MY, Zhang XH, et al
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-1632.
    PubMed     Abstract available


  93. MICHAUD DE, Guerriero JL
    Myeloid cells pave the metastatic road in breast cancer.
    Cancer Res. 2023 Dec 6. doi: 10.1158/0008-5472.CAN-23-3803.
    PubMed     Abstract available


    November 2023
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