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Articles published in Cancer Res

Retrieve available abstracts of 68 articles:
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Single Articles


    August 2026
  1. JIANG F, Chen L, Yang YC, Wang XM, et al
    Retraction: CYP3A5 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Regulating mTORC2/Akt Signaling.
    Cancer Res. 2026;86:4187-4188.
    PubMed    


    July 2026
  2. LI J, Ren Z, Yao J, Zhao Y, et al
    Mechanosensors Collaborate to Regulate DNA Damage Repair in Hepatocellular Carcinoma.
    Cancer Res. 2026 Jul 29. doi: 10.1158/0008-5472.CAN-25-4356.
    PubMed     Abstract available


  3. XU S, Huang JY, Wang K, Xiang YJ, et al
    ARID1A Stimulates Notch-TLL1 Signaling to Induce Cancer-Associated Fibroblast Activation and Intrahepatic Cholangiocarcinoma Development.
    Cancer Res. 2026 Jul 17. doi: 10.1158/0008-5472.CAN-25-5082.
    PubMed     Abstract available


  4. SUN T, Sun Q, Zhang X, Wang C, et al
    SEPTIN7 Enhances Tumorgenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling.
    Cancer Res. 2026 Jul 6. doi: 10.1158/0008-5472.CAN-25-5924.
    PubMed     Abstract available


  5. QIU W, Zeng Y, Fan Z, Su Y, et al
    An SLCO2B1 mRNA Isoform Acts as a Noncoding RNA to Drive Cancer Progression by Triggering Protein Biosynthesis.
    Cancer Res. 2026;86:3142-3159.
    PubMed     Abstract available


    June 2026
  6. GU H, Li F, Chen Y, Zhang M, et al
    EGFR N-Glycosylation Catalyzed by NDST2 Promotes Lenvatinib Resistance in Hepatocellular Carcinoma.
    Cancer Res. 2026 Jun 22. doi: 10.1158/0008-5472.CAN-25-4582.
    PubMed     Abstract available


  7. ZENG Y, Huang Z, Qiu J, Yuan G, et al
    HSPA6 Confers Lenvatinib Resistance in Hepatocellular Carcinoma by Promoting Phase Separation-Mediated TXNRD1 Stabilization to Suppress Ferroptosis.
    Cancer Res. 2026 Jun 18. doi: 10.1158/0008-5472.CAN-26-0314.
    PubMed     Abstract available


    May 2026
  8. SRIRAMAREDDY S, Siddarajappa N, Park JS, Nguyen T, et al
    GDF15 Reprograms the Microenvironment to Drive Liver Metastasis of Uveal Melanoma.
    Cancer Res. 2026 May 28. doi: 10.1158/0008-5472.CAN-25-0536.
    PubMed     Abstract available


    April 2026
  9. XU M, Gao X, Zhao J, Xu D, et al
    UFMylation Suppresses Hepatocellular Carcinoma Metastasis by Inhibiting beta-catenin-Driven Hybrid EMT and NK Cell Evasion.
    Cancer Res. 2026 Apr 17. doi: 10.1158/0008-5472.CAN-25-4755.
    PubMed     Abstract available


  10. GREENE E, Horvat NK, Doxie DB, Parihar VC, et al
    High-Dimensional Protein Analysis Uncovers Distinct Immunologic and Stromal Features in Primary and Metastatic Pancreatic Ductal Adenocarcinoma.
    Cancer Res. 2026;86:1753-1768.
    PubMed     Abstract available


    March 2026
  11. HAN L, Huo Y, Yang Y, Zhang L, et al
    The tRNA-Derived Fragment tRF-E Promotes Ferroptosis in Hepatocellular Carcinoma to Suppress Tumor Progression.
    Cancer Res. 2026 Mar 26. doi: 10.1158/0008-5472.CAN-25-2492.
    PubMed     Abstract available


  12. SUN Y, Luo C, Yang H, Ye J, et al
    Lactylation Converts ABHD6 into a Mitochondrial Regulator that Drives Lenvatinib Resistance in Hepatocellular Carcinoma.
    Cancer Res. 2026 Mar 20. doi: 10.1158/0008-5472.CAN-25-4282.
    PubMed     Abstract available


  13. BARROWS KM, Porat-Shliom N
    Hot Zones for Liver Cancer: Metabolic Zonation, Ferroptosis, and the Origins of HCC.
    Cancer Res. 2026;86:1347-1350.
    PubMed     Abstract available


    February 2026
  14. JO W, Park C, Kim M, Kim CS, et al
    Endotrophin and CD44-Mediated Heterotypic Signaling Mediates Tumor-Stroma Crosstalk and Facilitates Malignant Progression in Hepatocellular Carcinoma.
    Cancer Res. 2026 Feb 11. doi: 10.1158/0008-5472.CAN-25-3657.
    PubMed     Abstract available


    January 2026
  15. LIU Q, Liu Y, Zhou Y, Liang L, et al
    Intratumoral Lactobacillus johnsonii Enhances Sensitivity to PD-1 Blockade by Inducing CD8+ T Cell Expansion in Hepatocellular Carcinoma.
    Cancer Res. 2026 Jan 22. doi: 10.1158/0008-5472.CAN-25-0346.
    PubMed     Abstract available


    October 2025
  16. LIU S, Zhang Z, Wang Z, Liu C, et al
    SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.
    Cancer Res. 2025 Oct 6. doi: 10.1158/0008-5472.CAN-24-4916.
    PubMed     Abstract available


    September 2025
  17. MODL B, Zwolanek D, Schwertner K, Krauss D, et al
    TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-24-4224.
    PubMed     Abstract available


  18. CUI G, Zhou Y, Liao W, Cossu E, et al
    Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma.
    Cancer Res. 2025 Sep 12. doi: 10.1158/0008-5472.CAN-25-1615.
    PubMed     Abstract available


  19. FU C, Fu W, Huang Z, He X, et al
    Long-Chain Fatty Acid Redistribution Induced by SLC27A2 Deficiency Facilitates Hypoxic Adaptation and Immunosuppression in Hepatocellular Carcinoma.
    Cancer Res. 2025 Sep 3. doi: 10.1158/0008-5472.CAN-25-1693.
    PubMed     Abstract available


  20. WU YD, Huang XX, Zhang HX, Pan Y, et al
    TRAF3IP2-AS1 Deficiency Induces Necroptosis to Promote Pancreatic Cancer Liver Metastasis.
    Cancer Res. 2025;85:3292-3312.
    PubMed     Abstract available


    August 2025
  21. ZHENG Z, Yuan F, Li J, Zhu X, et al
    Gut Microbiota-Mediated Bile Acid Metabolism Regulates Colorectal Cancer Liver Metastasis by Altering Neutrophil Recruitment.
    Cancer Res. 2025 Aug 27. doi: 10.1158/0008-5472.CAN-24-4425.
    PubMed     Abstract available


  22. RUAN YH, Ning WR, Huang AQ, Jiang D, et al
    Intracellular Interleukin-1alpha in Peritumoral Monocytes Induces IL8 Production and Inhibits Mitophagy to Promote Stemness and Metastasis of Hepatocellular Carcinoma.
    Cancer Res. 2025 Aug 26. doi: 10.1158/0008-5472.CAN-24-3355.
    PubMed     Abstract available


  23. LIU Y, Liu FS, Liu J, Cairang D, et al
    The Acetyltransferase ARD1 Induces Glutathione Synthesis to Facilitate Ferroptosis Evasion in Hepatocellular Carcinoma.
    Cancer Res. 2025 Aug 21. doi: 10.1158/0008-5472.CAN-24-4015.
    PubMed     Abstract available


  24. GONG X, Ogino N, Leite MF, Zhang D, et al
    Adaptation to Volumetric Compression Drives an Apoptosis-Resistant and Invasive Phenotype in Liver Cancer.
    Cancer Res. 2025;85:3156-3175.
    PubMed     Abstract available


  25. CHEN K, Feng H, Zhang Y, Pei J, et al
    Tumor-derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma.
    Cancer Res. 2025 Aug 12. doi: 10.1158/0008-5472.CAN-24-4323.
    PubMed     Abstract available


  26. ZHANG X, Su T, Wu Y, Cai Y, et al
    Correction: N6-Methyladenosine Reader YTHDF1 Promotes Stemness and Therapeutic Resistance in Hepatocellular Carcinoma by Enhancing NOTCH1 Expression.
    Cancer Res. 2025;85:2953.
    PubMed    


    July 2025
  27. LI RZ, Pan GQ, Xiong C, Ding ZN, et al
    Hypoxia-Induced Creatine Uptake Reprograms Metabolism to Antagonize PARP1-Mediated Cell Death and Facilitate Tumor Progression in Hepatocellular Carcinoma.
    Cancer Res. 2025 Jul 31. doi: 10.1158/0008-5472.CAN-25-0301.
    PubMed     Abstract available


  28. YANG H, Cui J, Su P, Cui X, et al
    Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis.
    Cancer Res. 2025 Jul 31. doi: 10.1158/0008-5472.CAN-24-3405.
    PubMed     Abstract available


  29. LU J, Chan TT, Wang Y, Wang J, et al
    FADD Activation in Hepatocellular Carcinoma Potentiates CD8+T Cell Responses and Sensitizes to Immune Checkpoint Inhibitors.
    Cancer Res. 2025 Jul 14. doi: 10.1158/0008-5472.CAN-24-3854.
    PubMed     Abstract available


    May 2025
  30. PAPARGYRIOU A, Reichert M
    The Biology in the Pattern: Metastatic Organotropism and Clinical Outcome Depend on DNA Damage Response and Immune Interactions in Pancreatic Cancer.
    Cancer Res. 2025;85:1571-1573.
    PubMed     Abstract available


    March 2025
  31. LEE TKW, Ma S
    PROX1: a key regulator of hepatocyte identity and tumorigenesis.
    Cancer Res. 2025 Mar 31. doi: 10.1158/0008-5472.CAN-25-1377.
    PubMed     Abstract available


  32. CHANG Y, Wang N, Li S, Zhang J, et al
    SLC3A2-Mediated Lysine Uptake by Cancer Cells Restricts T cell Activity in Hepatocellular Carcinoma.
    Cancer Res. 2025 Mar 24. doi: 10.1158/0008-5472.CAN-24-3180.
    PubMed     Abstract available


  33. WANG M, Zou F, Wang S, Yang Y, et al
    CRTC2 Forms Co-condensates with YTHDF2 that Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance.
    Cancer Res. 2025 Mar 4. doi: 10.1158/0008-5472.CAN-24-3196.
    PubMed     Abstract available


    January 2025
  34. CHEN R, Ma C, Qian H, Xie X, et al
    Mutant KRAS and CK2 Cooperatively Stimulate SLC16A3 Activity to Drive Intrahepatic Cholangiocarcinoma Progression.
    Cancer Res. 2025 Jan 24. doi: 10.1158/0008-5472.CAN-24-2097.
    PubMed     Abstract available


  35. XIE P, Guo L, Yu Q, Zhao Y, et al
    ACE2 Enhances Sensitivity to PD-L1 Blockade by Inhibiting Macrophage-Induced Immunosuppression and Angiogenesis.
    Cancer Res. 2025;85:299-313.
    PubMed     Abstract available


  36. LUO YW, Fang Y, Zeng HX, Ji YC, et al
    HIF1alpha Counteracts TGFbeta1-Driven TSP1 Expression in Endothelial Cells to Stimulate Angiogenesis in the Hypoxic Tumor Microenvironment.
    Cancer Res. 2025;85:69-83.
    PubMed     Abstract available


    December 2024
  37. XUE S, Chen X, Qiu G, Liao H, et al
    CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis.
    Cancer Res. 2024 Dec 18. doi: 10.1158/0008-5472.CAN-24-0147.
    PubMed     Abstract available


  38. TURNHAM RE, Pitea A, Jang GM, Xu Z, et al
    HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.
    Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-0456.
    PubMed     Abstract available


  39. YANG Y, Luo J, Wang Z, Liu K, et al
    Energy Stress-induced CircEPB41(2) Promotes Lipogenesis in Hepatocellular Carcinoma.
    Cancer Res. 2024 Dec 5. doi: 10.1158/0008-5472.CAN-24-1630.
    PubMed     Abstract available


    November 2024
  40. ZHANG Q, Zhang Y, Fu C, He X, et al
    CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A Modification Evasion of PGK1 to Enhance Glycolysis.
    Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-2283.
    PubMed     Abstract available


    October 2024
  41. CUI Y, Chang Y, Ma X, Sun M, et al
    Ephrin A1 Stimulates CCL2 Secretion to Facilitate Pre-metastatic Niche Formation and Promote Gastric Cancer Liver Metastasis.
    Cancer Res. 2024 Oct 16. doi: 10.1158/0008-5472.CAN-24-1254.
    PubMed     Abstract available


    September 2024
  42. CONNER SJ, Borges HB, Guarin JR, Gerton TJ, et al
    Obesity Induces Temporally Regulated Alterations in the Extracellular Matrix That Drive Breast Tumor Invasion and Metastasis.
    Cancer Res. 2024;84:2761-2775.
    PubMed     Abstract available


  43. SHU Y, Jin X, Ji M, Zhang Z, et al
    Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and Tumorigenesis.
    Cancer Res. 2024;84:2836-2855.
    PubMed     Abstract available


  44. HOU PP, Zheng CM, Wu SH, Liu XX, et al
    Extracellular Vesicle-Packaged ACSL4 Induces Hepatocyte Senescence to Promote Hepatocellular Carcinoma Progression.
    Cancer Res. 2024 Sep 3. doi: 10.1158/0008-5472.CAN-24-0832.
    PubMed     Abstract available


    August 2024
  45. ZHANG S, Deshpande A, Verma BK, Wang H, et al
    Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery.
    Cancer Res. 2024;84:2734-2748.
    PubMed     Abstract available


    July 2024
  46. LIAO S, Deng J, Deng M, Chen C, et al
    AFDN deficiency promotes liver tropism of metastatic colorectal cancer.
    Cancer Res. 2024 Jul 24. doi: 10.1158/0008-5472.CAN-23-3140.
    PubMed     Abstract available


    June 2024
  47. SHIRANI M, Levin S, Shebl B, Requena D, et al
    Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1.
    Cancer Res. 2024 Jun 18. doi: 10.1158/0008-5472.CAN-23-4110.
    PubMed     Abstract available


  48. LI L, Xie D, Yu S, Ma M, et al
    WNK1 Interaction with KEAP1 Promotes NRF2 Stabilization to Enhance the Oxidative Stress Response in Hepatocellular Carcinoma.
    Cancer Res. 2024 Jun 17. doi: 10.1158/0008-5472.CAN-23-1167.
    PubMed     Abstract available


    May 2024
  49. RETTIG AR, Ganesh K
    Cancer Cells Hijack Physiologic Metabolic Signals to Seed Liver Metastasis.
    Cancer Res. 2024;84:1548-1549.
    PubMed     Abstract available


  50. HE W, Wang M, Zhang X, Wang Y, et al
    Estrogen induces LCAT to maintain cholesterol homeostasis and suppress hepatocellular carcinoma development.
    Cancer Res. 2024 May 8. doi: 10.1158/0008-5472.CAN-23-3966.
    PubMed     Abstract available


  51. ZHANG R, Li S, Schippers K, Li Y, et al
    Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate beta-Catenin Signaling.
    Cancer Res. 2024;84:1443-1459.
    PubMed     Abstract available


    April 2024
  52. YANG S, Zhang D, Sun Q, Nie H, et al
    Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
    Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-3264.
    PubMed     Abstract available


    March 2024
  53. HUANG J, Tsang WY, Fang XN, Zhang Y, et al
    FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma.
    Cancer Res. 2024;84:855-871.
    PubMed     Abstract available


  54. WENG J, Wang Z, Hu Z, Xu W, et al
    Repolarization of immunosuppressive macrophages by targeting SLAMF7-regulated CCL2 signaling sensitizes hepatocellular carcinoma to immunotherapy.
    Cancer Res. 2024 Mar 14. doi: 10.1158/0008-5472.CAN-23-3106.
    PubMed     Abstract available


  55. LIAO H, Chen X, Wang H, Lin Y, et al
    Whole-genome DNA methylation profiling of intrahepatic cholangiocarcinoma reveals prognostic subtypes with distinct biological drivers.
    Cancer Res. 2024 Mar 12. doi: 10.1158/0008-5472.CAN-23-3298.
    PubMed     Abstract available


  56. WAN S, He QY, Yang Y, Liu F, et al
    SPARC stabilizes ApoE to induce cholesterol-dependent invasion and sorafenib resistance in hepatocellular carcinoma.
    Cancer Res. 2024 Mar 12. doi: 10.1158/0008-5472.CAN-23-2889.
    PubMed     Abstract available


    February 2024
  57. WANG Y, Cheng C, Lu Y, Lian Z, et al
    beta-catenin Activation Reprograms Ammonia Metabolism to Promote Senescence Resistance in Hepatocellular Carcinoma.
    Cancer Res. 2024 Feb 28. doi: 10.1158/0008-5472.CAN-23-0673.
    PubMed     Abstract available


  58. SONG M, Zhang C, Cheng S, Ouyang D, et al
    DNA of neutrophil extracellular traps binds TMCO6 to impair CD8+ T-cell immunity in hepatocellular carcinoma.
    Cancer Res. 2024 Feb 21. doi: 10.1158/0008-5472.CAN-23-2986.
    PubMed     Abstract available


  59. LIU X, Wang X, Yang Q, Luo L, et al
    Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis.
    Cancer Res. 2024 Feb 9. doi: 10.1158/0008-5472.CAN-23-2123.
    PubMed     Abstract available


    January 2024
  60. ZHANG X, Su T, Wu Y, Cai Y, et al
    N6-methyladenosine reader YTHDF1 promotes stemness and therapeutic resistance in hepatocellular carcinoma by enhancing NOTCH1 expression.
    Cancer Res. 2024 Jan 19. doi: 10.1158/0008-5472.CAN-23-1916.
    PubMed     Abstract available


  61. MU M, Huang CX, Qu C, Li PL, et al
    Targeting ferroptosis-elicited inflammation suppresses hepatocellular carcinoma metastasis and enhances sorafenib efficacy.
    Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1796.
    PubMed     Abstract available


    December 2023
  62. DATTA J, Kutay H, Nasser MW, Nuovo GJ, et al
    Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis.
    Cancer Res. 2023;83:4181.
    PubMed    


  63. MAJUMDER S, Roy S, Kaffenberger T, Wang B, et al
    Retraction: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-kappaB Target Genes.
    Cancer Res. 2023;83:4179.
    PubMed    


    November 2023
  64. ZHUANG Q, Dai Z, Xu X, Bai S, et al
    RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion.
    Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-2049.
    PubMed     Abstract available


  65. CHEN Z, Zhang G, Ren X, Yao Z, et al
    Cross-talk between Myeloid and B Cells Shapes the Distinct Microenvironments of Primary and Secondary Liver Cancer.
    Cancer Res. 2023;83:3544-3561.
    PubMed     Abstract available


    September 2023
  66. SU T, Zhang N, Wang T, Zeng J, et al
    Super enhancer-regulated lncRNA LINC01089 induces alternative splicing of DIAPH3 to drive hepatocellular carcinoma metastasis.
    Cancer Res. 2023 Sep 26. doi: 10.1158/0008-5472.CAN-23-0544.
    PubMed     Abstract available


  67. HUNG MH, Wang XW
    Targeting WNT/beta-catenin via modulating EZH2 function - a new chapter in the treatment of beta-catenin mutant hepatocellular carcinoma?
    Cancer Res. 2023 Sep 25. doi: 10.1158/0008-5472.CAN-23-2921.
    PubMed     Abstract available


    August 2023
  68. ZHENG Y, Zhou R, Cai J, Yang N, et al
    Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases.
    Cancer Res. 2023 Aug 23:CAN-23-0025. doi: 10.1158/0008-5472.CAN-23-0025.
    PubMed     Abstract available


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