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Leukemia

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 55 articles: HTML format

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April 2021
1. RIVERA OD, Mallory MJ, Quesnel-Vallieres M, Chatrikhi R, et al
   Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   March 2021
2. OWEN N, Minko IG, Moellmer SA, Cammann SK, et al
   Enhanced cytarabine-induced killing in OGG1-deficient acute myeloid leukemia cells.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   
3. HE Y, Pasupala N, Zhi H, Dorjbal B, et al
   NF-kappaB-induced R-loop accumulation and DNA damage select for nucleotide excision repair deficiencies in adult T cell leukemia.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   February 2021
4. PAN L, Hong C, Chan LN, Xiao G, et al
   PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   
5. CHEN L, Zhu HM, Li Y, Liu QF, et al
   Arsenic trioxide replacing or reducing chemotherapy in consolidation therapy for acute promyelocytic leukemia (APL2012 trial).
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   
6. LEE YL, Ito K, Pi WC, Lin IH, et al
   Mediator subunit MED1 is required for E2A-PBX1-mediated oncogenic transcription and leukemic cell growth.
   Proc Natl Acad Sci U S A. 2021;118.
   PubMed     Abstract available
   
   
   November 2020
7. YEH JX, Schultz KLW, Calvert V, Petricoin EF, et al
   The NF-kappaB/leukemia inhibitory factor/STAT3 signaling pathway in antibody-mediated suppression of Sindbis virus replication in neurons.
   Proc Natl Acad Sci U S A. 2020 Nov 3. pii: 2016691117.
   PubMed     Abstract available
   
   
   October 2020
8. BILL M, Mrozek K, Kohlschmidt J, Eisfeld AK, et al
   Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A.
   Proc Natl Acad Sci U S A. 2020 Oct 5. pii: 2014732117.
   PubMed     Abstract available
   
   
   September 2020
9. KRENN PW, Koschmieder S, Fassler R
   Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches.
   Proc Natl Acad Sci U S A. 2020 Sep 14. pii: 2009078117.
   PubMed     Abstract available
   
   
   
10. 
    Correction for Chen et al., Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2020 Sep 8. pii: 2017617117.
    PubMed    
    
    
    August 2020
11. SEONG D, Jeong M, Seo J, Lee JY, et al
    Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formation.
    Proc Natl Acad Sci U S A. 2020;117:19982-19993.
    PubMed     Abstract available
    
    
    
12. JIANG L, Li XP, Dai YT, Chen B, et al
    Multidimensional study of the heterogeneity of leukemia cells in t(8;21) acute myelogenous leukemia identifies the subtype with poor outcome.
    Proc Natl Acad Sci U S A. 2020 Aug 3. pii: 2003900117.
    PubMed     Abstract available
    
    
    June 2020
13. QIAO X, van der Zanden SY, Wander DPA, Borras DM, et al
    Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.
    Proc Natl Acad Sci U S A. 2020;117:15182-15192.
    PubMed     Abstract available
    
    
    
14. MU L, Kang JH, Olcum S, Payer KR, et al
    Mass measurements during lymphocytic leukemia cell polyploidization decouple cell cycle- and cell size-dependent growth.
    Proc Natl Acad Sci U S A. 2020 Jun 24. pii: 1922197117.
    PubMed     Abstract available
    
    
    
15. LAMBLE AJ, Kosaka Y, Laderas T, Maffit A, et al
    Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2020 Jun 8. pii: 1916206117.
    PubMed     Abstract available
    
    
    May 2020
16. BRAUN TP, Coblentz C, Smith BM, Coleman DJ, et al
    Combined inhibition of JAK/STAT pathway and lysine-specific demethylase 1 as a therapeutic strategy in CSF3R/CEBPA mutant acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2020 May 29. pii: 1918307117.
    PubMed     Abstract available
    
    
    
17. LOVAT F, Nigita G, Distefano R, Nakamura T, et al
    Combined loss of function of two different loci of miR-15/16 drives the pathogenesis of acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2020 May 18. pii: 2003597117.
    PubMed     Abstract available
    
    
    
18. NAGASAKA M, Yamagishi M, Yagishita N, Araya N, et al
    Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis.
    Proc Natl Acad Sci U S A. 2020 May 11. pii: 1920346117.
    PubMed     Abstract available
    
    
    February 2020
19. MAITY PC, Bilal M, Koning MT, Young M, et al
    IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling.
    Proc Natl Acad Sci U S A. 2020;117:4320-4327.
    PubMed     Abstract available
    
    
    January 2020
20. KOSLOVA A, Trefil P, Mucksova J, Reinisova M, et al
    Precise CRISPR/Cas9 editing of the NHE1 gene renders chickens resistant to the J subgroup of avian leukosis virus.
    Proc Natl Acad Sci U S A. 2020;117:2108-2112.
    PubMed     Abstract available
    
    
    November 2019
21. AGARWAL A, Bolosky WJ, Wilson DB, Eide CA, et al
    Differentiation of leukemic blasts is not completely blocked in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2019 Nov 21. pii: 1904091116.
    PubMed     Abstract available
    
    
    
22. VENEZIANO D, Tomasello L, Balatti V, Palamarchuk A, et al
    Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2019 Nov 13. pii: 1913695116.
    PubMed     Abstract available
    
    
    September 2019
23. GE C, Huang H, Huang F, Yang T, et al
    Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload.
    Proc Natl Acad Sci U S A. 2019 Sep 5. pii: 1908998116.
    PubMed     Abstract available
    
    
    July 2019
24. KIM JH, Penson AV, Taylor BS, Petrini JHJ, et al
    Nbn-Mre11 interaction is required for tumor suppression and genomic integrity.
    Proc Natl Acad Sci U S A. 2019;116:15178-15183.
    PubMed     Abstract available
    
    
    May 2019
25. MA L, Pak ML, Ou J, Yu J, et al
    Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells.
    Proc Natl Acad Sci U S A. 2019 May 8. pii: 1903550116.
    PubMed     Abstract available
    
    
    
26. HORIBATA S, Gui G, Lack J, DeStefano CB, et al
    Heterogeneity in refractory acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2019 May 7. pii: 1902375116.
    PubMed     Abstract available
    
    
    March 2019
27. SCHIAVON V, Duchez S, Branchtein M, How-Kit A, et al
    Microenvironment tailors nTreg structure and function.
    Proc Natl Acad Sci U S A. 2019;116:6298-6307.
    PubMed     Abstract available
    
    
    February 2019
28. POULARD C, Kim HN, Fang M, Kruth K, et al
    Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 1816254116.
    PubMed     Abstract available
    
    
    
29. CHEN XJ, Zhang WN, Chen B, Xi WD, et al
    Homoharringtonine deregulates MYC transcriptional expression by directly binding NF-kappaB repressing factor.
    Proc Natl Acad Sci U S A. 2019;116:2220-2225.
    PubMed     Abstract available
    
    
    January 2019
30. LEUNG KK, Nguyen A, Shi T, Tang L, et al
    Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.
    Proc Natl Acad Sci U S A. 2019;116:695-700.
    PubMed     Abstract available
    
    
    December 2018
31. LIU N, Song J, Xie Y, Wang XL, et al
    Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.
    Proc Natl Acad Sci U S A. 2018 Dec 28. pii: 1809327116.
    PubMed     Abstract available
    
    
    November 2018
32. LI JF, Dai YT, Lilljebjorn H, Shen SH, et al
    Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases.
    Proc Natl Acad Sci U S A. 2018 Nov 28. pii: 1814397115.
    PubMed     Abstract available
    
    
    
33. QU K, Glass B, Dolezal M, Schur FKM, et al
    Structure and architecture of immature and mature murine leukemia virus capsids.
    Proc Natl Acad Sci U S A. 2018 Nov 26. pii: 1811580115.
    PubMed     Abstract available
    
    
    
34. LOVAT F, Fassan M, Sacchi D, Ranganathan P, et al
    Knockout of both miR-15/16 loci induces acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2018 Nov 26. pii: 1814980115.
    PubMed     Abstract available
    
    
    October 2018
35. KNECHT KM, Buzovetsky O, Schneider C, Thomas D, et al
    The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1.
    Proc Natl Acad Sci U S A. 2018;115:E10022-E10031.
    PubMed     Abstract available
    
    
    
36. DAS P, Veazey KJ, Van HT, Kaushik S, et al
    Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches.
    Proc Natl Acad Sci U S A. 2018;115:E10137-E10146.
    PubMed     Abstract available
    
    
    
37. FEI DL, Zhen T, Durham B, Ferrarone J, et al
    Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1.
    Proc Natl Acad Sci U S A. 2018 Oct 15. pii: 1812669115.
    PubMed     Abstract available
    
    
    
38. KATSUMURA KR, Mehta C, Hewitt KJ, Soukup AA, et al
    Human leukemia mutations corrupt but do not abrogate GATA-2 function.
    Proc Natl Acad Sci U S A. 2018 Oct 9. pii: 1813015115.
    PubMed     Abstract available
    
    
    September 2018
39. JAMROG L, Chemin G, Fregona V, Coster L, et al
    PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice.
    Proc Natl Acad Sci U S A. 2018 Sep 26. pii: 1721678115.
    PubMed     Abstract available
    
    
    May 2018
40. ANCHANG B, Davis KL, Fienberg HG, Williamson BD, et al
    DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity.
    Proc Natl Acad Sci U S A. 2018;115:E4294-E4303.
    PubMed     Abstract available
    
    
    April 2018
41. WEI J, Bera TK, Liu XF, Zhou Q, et al
    Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity.
    Proc Natl Acad Sci U S A. 2018;115:E3501-E3508.
    PubMed     Abstract available
    
    
    March 2018
42. POLLOCK SB, Hu A, Mou Y, Martinko AJ, et al
    Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.
    Proc Natl Acad Sci U S A. 2018;115:2836-2841.
    PubMed     Abstract available
    
    
    February 2018
43. ZEISIG BB, So CWE
    MLL-AF4, a double-edged sword for iPSC respecification into HSPCs.
    Proc Natl Acad Sci U S A. 2018;115:1964-1966.
    PubMed    
    
    
    
44. MAHGOUB M, Yasunaga JI, Iwami S, Nakaoka S, et al
    Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells.
    Proc Natl Acad Sci U S A. 2018;115:E1269-E1278.
    PubMed     Abstract available
    
    
    
45. MULLER F, Cunningham T, Stookey S, Tai CH, et al
    5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox.
    Proc Natl Acad Sci U S A. 2018 Feb 5. pii: 1714512115.
    PubMed     Abstract available
    
    
    January 2018
46. TAN Q, Brunetti L, Rousseaux MWC, Lu HC, et al
    Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
    Proc Natl Acad Sci U S A. 2018 Jan 30. pii: 1716452115.
    PubMed     Abstract available
    
    
    
47. MAZOR R, King EM, Onda M, Cuburu N, et al
    Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity.
    Proc Natl Acad Sci U S A. 2018;115:E733-E742.
    PubMed     Abstract available
    
    
    December 2017
48. CHEN B, Jiang L, Zhong ML, Li JF, et al
    Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2017 Dec 26. pii: 1717125115.
    PubMed     Abstract available
    
    
    October 2017
49. KANJEE U, Gruring C, Chaand M, Lin KM, et al
    CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent erythrocyte determinants of Plasmodium falciparum invasion.
    Proc Natl Acad Sci U S A. 2017;114:E9356-E9365.
    PubMed     Abstract available
    
    
    September 2017
50. RASSENTI LZ, Balatti V, Ghia EM, Palamarchuk A, et al
    MicroRNA dysregulation to identify therapeutic target combinations for chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2017 Sep 18. pii: 201708264.
    PubMed     Abstract available
    
    
    May 2017
51. PAPAIOANNOU D, Shen C, Nicolet D, McNeil B, et al
    Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2017 May 22. pii: 201703142.
    PubMed     Abstract available
    
    
    
52. DAI YJ, Wang YY, Huang JY, Xia L, et al
    Conditional knockin of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement.
    Proc Natl Acad Sci U S A. 2017 May 1. pii: 201703476.
    PubMed     Abstract available
    
    
    
53. SCHWARTZMAN O, Savino AM, Gombert M, Palmi C, et al
    Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome.
    Proc Natl Acad Sci U S A. 2017 May 1. pii: 201702489.
    PubMed     Abstract available
    
    
    March 2017
54. FABBRI G, Holmes AB, Viganotti M, Scuoppo C, et al
    Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2017 Mar 17. pii: 201702564.
    PubMed     Abstract available
    
    
    December 2016
55. LEMONNIER F, Cairns RA, Inoue S, Li WY, et al
    The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
    Proc Natl Acad Sci U S A. 2016 Dec 12. pii: 201617929.
    PubMed     Abstract available
    
    

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