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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 30 articles:
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Single Articles


    July 2025
  1. ZHANG W, Shichijo T, Chen X, Watanabe M, et al
    JunB-HBZ nuclear translocation by TGF-beta is a key driver in HTLV-1-mediated leukemogenesis.
    Proc Natl Acad Sci U S A. 2025;122:e2420756122.
    PubMed     Abstract available


    June 2025
  2. MOBACH S, Bergkamp ND, Ma Z, Haselager MV, et al
    Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.
    Proc Natl Acad Sci U S A. 2025;122:e2424186122.
    PubMed     Abstract available


    May 2025
  3. HOSSEINI A, Qiu X, Xiong Y, Chiang KHN, et al
    Discovery of an LSD1 PROTAC degrader.
    Proc Natl Acad Sci U S A. 2025;122:e2425812122.
    PubMed     Abstract available


  4. SAKAMOTO T, Leca J, Zhang X, Meydan C, et al
    Mutant IDH1 cooperates with NPM1c or FLT3(ITD) to drive distinct myeloid diseases and molecular outcomes.
    Proc Natl Acad Sci U S A. 2025;122:e2415779122.
    PubMed     Abstract available


    April 2025
  5. BERTULFO K, Perez-Duran P, Miller H, Ma C, et al
    Therapeutic targeting of the NOTCH1 and neddylation pathways in T cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2426742122.
    PubMed     Abstract available



  6. Correction to Supporting Information for Wang et al., Metabolomic insights into pathogenesis and therapeutic potential in adult acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2504173122.
    PubMed    


    March 2025
  7. XU S, Hong J, Dongye M, Lin J, et al
    The synergistic effect of c-Myb hyperactivation and Pu.1 deficiency induces Pelger-Huet anomaly and promotes sAML.
    Proc Natl Acad Sci U S A. 2025;122:e2416121122.
    PubMed     Abstract available


    February 2025
  8. LIU B, Yasunaga JI, Liang Y, Zhou R, et al
    Identification of AK4 and RHOC as potential oncogenes addicted by adult T cell leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2416412122.
    PubMed     Abstract available


  9. WANG JY, Gui TT, Jiao B, Liu X, et al
    Metabolomic insights into pathogenesis and therapeutic potential in adult acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2423169122.
    PubMed     Abstract available


  10. JIN GB, Rong SQ, Yin DR, Deng ZH, et al
    Neomorphic leukemia-derived mutations in the TET2 enzyme induce genome instability via a substrate shift from 5-methylcytosine to thymine.
    Proc Natl Acad Sci U S A. 2025;122:e2418318122.
    PubMed     Abstract available


    January 2025
  11. DONG Z, Sepulveda H, Arteaga-Vazquez LJ, Blouin C, et al
    A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2413302121.
    PubMed     Abstract available


    December 2024
  12. NGUYEN HN, Jeong Y, Kim Y, Kamiya M, et al
    Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis.
    Proc Natl Acad Sci U S A. 2024;121:e2401899121.
    PubMed     Abstract available


    October 2024

  13. Correction for Garzon et al., Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
    Proc Natl Acad Sci U S A. 2024;121:e2419360121.
    PubMed    


  14. FU A, Luo Z, Ziv T, Bi X, et al
    Nuclear p62 condensates stabilize the promyelocytic leukemia nuclear bodies by sequestering their ubiquitin ligase RNF4.
    Proc Natl Acad Sci U S A. 2024;121:e2414377121.
    PubMed     Abstract available


    September 2024

  15. Correction for Garzon et al., Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
    Proc Natl Acad Sci U S A. 2024;121:e2415544121.
    PubMed    


    August 2024
  16. ZHANG Y, Lou J, Liu Y, Jin P, et al
    Phase separation of PML/RARalpha and BRD4 coassembled microspeckles governs transcriptional dysregulation in acute promyelocytic leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2406519121.
    PubMed     Abstract available


  17. LUO Y, Su B, Hung V, Luo Y, et al
    IL-1 receptor antagonism reveals a yin-yang relationship between NFkappaB and interferon signaling in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2405644121.
    PubMed     Abstract available


    July 2024
  18. ZHONG X, Moresco JJ, SoRelle JA, Song R, et al
    Disruption of the ZFP574-THAP12 complex suppresses B cell malignancies in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2409232121.
    PubMed     Abstract available


    June 2024
  19. SMOLKO AE, Sullivan DW, Olsen SN, Kang H, et al
    A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes.
    Proc Natl Acad Sci U S A. 2024;121:e2405905121.
    PubMed     Abstract available


  20. WINDISCH R, Soliman S, Hoffmann A, Chen-Wichmann L, et al
    Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
    Proc Natl Acad Sci U S A. 2024;121:e2312499121.
    PubMed     Abstract available


    May 2024
  21. WOLF KMP, Maffeis V, Schoenenberger CA, Zund T, et al
    Tweaking the NRF2 signaling cascade in human myelogenous leukemia cells by artificial nano-organelles.
    Proc Natl Acad Sci U S A. 2024;121:e2219470121.
    PubMed     Abstract available


    April 2024
  22. KATERNDAHL CDS, Rogers ORS, Day RB, Xu Z, et al
    PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells.
    Proc Natl Acad Sci U S A. 2024;121:e2317690121.
    PubMed     Abstract available


  23. KRISTENSON L, Badami C, Ljungberg A, Islamagic E, et al
    Deletion of the TMEM30A gene enables leukemic cell evasion of NK cell cytotoxicity.
    Proc Natl Acad Sci U S A. 2024;121:e2316447121.
    PubMed     Abstract available


    March 2024
  24. SHICHIJO T, Yasunaga JI, Sato K, Nosaka K, et al
    Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.
    Proc Natl Acad Sci U S A. 2024;121:e2309925121.
    PubMed     Abstract available


  25. LI JF, Cheng WY, Lin XJ, Wen LJ, et al
    Aging and comprehensive molecular profiling in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2319366121.
    PubMed     Abstract available


  26. ROSELLE C, Horikawa I, Chen L, Kelly AR, et al
    Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Delta133p53alpha.
    Proc Natl Acad Sci U S A. 2024;121:e2317735121.
    PubMed     Abstract available


  27. KATSUMURA KR, Liu P, Kim JA, Mehta C, et al
    Pathogenic GATA2 genetic variants utilize an obligate enhancer mechanism to distort a multilineage differentiation program.
    Proc Natl Acad Sci U S A. 2024;121:e2317147121.
    PubMed     Abstract available


    February 2024
  28. MOTTAGHINIA S, Stenzel S, Tsangaras K, Nikolaidis N, et al
    A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea.
    Proc Natl Acad Sci U S A. 2024;121:e2220392121.
    PubMed     Abstract available


    October 2023
  29. FERLITA A, Nigita G, Tsyba L, Palamarchuk A, et al
    Expression signature of human endogenous retroviruses in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2023;120:e2307593120.
    PubMed     Abstract available


  30. NG A, Lovat F, Shih AJ, Ma Y, et al
    Complete miRNA-15/16 loss in mice promotes hematopoietic progenitor expansion and a myeloid-biased hyperproliferative state.
    Proc Natl Acad Sci U S A. 2023;120:e2308658120.
    PubMed     Abstract available


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