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By B. S. Kamps et al.


  Leukemia

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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 56 articles:
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Single Articles


    February 2025
  1. WANG JY, Gui TT, Jiao B, Liu X, et al
    Metabolomic insights into pathogenesis and therapeutic potential in adult acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2423169122.
    PubMed     Abstract available


  2. JIN GB, Rong SQ, Yin DR, Deng ZH, et al
    Neomorphic leukemia-derived mutations in the TET2 enzyme induce genome instability via a substrate shift from 5-methylcytosine to thymine.
    Proc Natl Acad Sci U S A. 2025;122:e2418318122.
    PubMed     Abstract available


    January 2025
  3. DONG Z, Sepulveda H, Arteaga-Vazquez LJ, Blouin C, et al
    A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2413302121.
    PubMed     Abstract available


    December 2024
  4. NGUYEN HN, Jeong Y, Kim Y, Kamiya M, et al
    Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis.
    Proc Natl Acad Sci U S A. 2024;121:e2401899121.
    PubMed     Abstract available


    October 2024

  5. Correction for Garzon et al., Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
    Proc Natl Acad Sci U S A. 2024;121:e2419360121.
    PubMed    


  6. FU A, Luo Z, Ziv T, Bi X, et al
    Nuclear p62 condensates stabilize the promyelocytic leukemia nuclear bodies by sequestering their ubiquitin ligase RNF4.
    Proc Natl Acad Sci U S A. 2024;121:e2414377121.
    PubMed     Abstract available


    September 2024

  7. Correction for Garzon et al., Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
    Proc Natl Acad Sci U S A. 2024;121:e2415544121.
    PubMed    


    August 2024
  8. ZHANG Y, Lou J, Liu Y, Jin P, et al
    Phase separation of PML/RARalpha and BRD4 coassembled microspeckles governs transcriptional dysregulation in acute promyelocytic leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2406519121.
    PubMed     Abstract available


  9. LUO Y, Su B, Hung V, Luo Y, et al
    IL-1 receptor antagonism reveals a yin-yang relationship between NFkappaB and interferon signaling in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2405644121.
    PubMed     Abstract available


    July 2024
  10. ZHONG X, Moresco JJ, SoRelle JA, Song R, et al
    Disruption of the ZFP574-THAP12 complex suppresses B cell malignancies in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2409232121.
    PubMed     Abstract available


    June 2024
  11. SMOLKO AE, Sullivan DW, Olsen SN, Kang H, et al
    A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes.
    Proc Natl Acad Sci U S A. 2024;121:e2405905121.
    PubMed     Abstract available


  12. WINDISCH R, Soliman S, Hoffmann A, Chen-Wichmann L, et al
    Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
    Proc Natl Acad Sci U S A. 2024;121:e2312499121.
    PubMed     Abstract available


    May 2024
  13. WOLF KMP, Maffeis V, Schoenenberger CA, Zund T, et al
    Tweaking the NRF2 signaling cascade in human myelogenous leukemia cells by artificial nano-organelles.
    Proc Natl Acad Sci U S A. 2024;121:e2219470121.
    PubMed     Abstract available


    April 2024
  14. KATERNDAHL CDS, Rogers ORS, Day RB, Xu Z, et al
    PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells.
    Proc Natl Acad Sci U S A. 2024;121:e2317690121.
    PubMed     Abstract available


  15. KRISTENSON L, Badami C, Ljungberg A, Islamagic E, et al
    Deletion of the TMEM30A gene enables leukemic cell evasion of NK cell cytotoxicity.
    Proc Natl Acad Sci U S A. 2024;121:e2316447121.
    PubMed     Abstract available


    March 2024
  16. SHICHIJO T, Yasunaga JI, Sato K, Nosaka K, et al
    Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.
    Proc Natl Acad Sci U S A. 2024;121:e2309925121.
    PubMed     Abstract available


  17. LI JF, Cheng WY, Lin XJ, Wen LJ, et al
    Aging and comprehensive molecular profiling in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2319366121.
    PubMed     Abstract available


  18. ROSELLE C, Horikawa I, Chen L, Kelly AR, et al
    Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Delta133p53alpha.
    Proc Natl Acad Sci U S A. 2024;121:e2317735121.
    PubMed     Abstract available


  19. KATSUMURA KR, Liu P, Kim JA, Mehta C, et al
    Pathogenic GATA2 genetic variants utilize an obligate enhancer mechanism to distort a multilineage differentiation program.
    Proc Natl Acad Sci U S A. 2024;121:e2317147121.
    PubMed     Abstract available


    February 2024
  20. MOTTAGHINIA S, Stenzel S, Tsangaras K, Nikolaidis N, et al
    A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea.
    Proc Natl Acad Sci U S A. 2024;121:e2220392121.
    PubMed     Abstract available


    October 2023
  21. FERLITA A, Nigita G, Tsyba L, Palamarchuk A, et al
    Expression signature of human endogenous retroviruses in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2023;120:e2307593120.
    PubMed     Abstract available


  22. NG A, Lovat F, Shih AJ, Ma Y, et al
    Complete miRNA-15/16 loss in mice promotes hematopoietic progenitor expansion and a myeloid-biased hyperproliferative state.
    Proc Natl Acad Sci U S A. 2023;120:e2308658120.
    PubMed     Abstract available


    August 2023
  23. SAUNDERSON EA, Encabo HH, Devis J, Rouault-Pierre K, et al
    CRISPR/dCas9 DNA methylation editing is heritable during human hematopoiesis and shapes immune progeny.
    Proc Natl Acad Sci U S A. 2023;120:e2300224120.
    PubMed     Abstract available


  24. BEAUVOIS A, Gazon H, Chauhan PS, Jamakhani M, et al
    The helicase-like transcription factor redirects the autophagic flux and restricts human T cell leukemia virus type 1 infection.
    Proc Natl Acad Sci U S A. 2023;120:e2216127120.
    PubMed     Abstract available


    April 2023
  25. WRIGHT S, Hu J, Wang H, Hyle J, et al
    Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens.
    Proc Natl Acad Sci U S A. 2023;120:e2220134120.
    PubMed     Abstract available


    March 2023
  26. HUANG D, Zhang C, Xiao M, Li X, et al
    Redox metabolism maintains the leukemogenic capacity and drug resistance of AML cells.
    Proc Natl Acad Sci U S A. 2023;120:e2210796120.
    PubMed     Abstract available


    February 2023
  27. YUITA H, Lopez-Moyado IF, Jeong H, Cheng AX, et al
    Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch.
    Proc Natl Acad Sci U S A. 2023;120:e2214824120.
    PubMed     Abstract available


    December 2022
  28. CHENG WY, Li JF, Zhu YM, Lin XJ, et al
    Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2022;119:e2211429119.
    PubMed     Abstract available


    October 2022
  29. CHEN Q, Cevher MA, Jiang Q, Wang S, et al
    LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML.
    Proc Natl Acad Sci U S A. 2022;119:e2213718119.
    PubMed     Abstract available


    September 2022
  30. RAHMAN S, Hoffmann NA, Worden EJ, Smith ML, et al
    Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
    Proc Natl Acad Sci U S A. 2022;119:e2205691119.
    PubMed     Abstract available


    August 2022
  31. ARNOVITZ S, Mathur P, Tracy M, Mohsin A, et al
    Tcf-1 promotes genomic instability and T cell transformation in response to aberrant beta-catenin activation.
    Proc Natl Acad Sci U S A. 2022;119:e2201493119.
    PubMed     Abstract available


    July 2022
  32. KOGAN AA, Topper MJ, Dellomo AJ, Stojanovic L, et al
    Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2022;119:e2123227119.
    PubMed     Abstract available


  33. LAFFEY KG, Stiles RJ, Ludescher MJ, Davis TR, et al
    Early expression of mature alphabeta TCR in CD4(-)CD8(-) T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations.
    Proc Natl Acad Sci U S A. 2022;119:e2118529119.
    PubMed     Abstract available


    June 2022
  34. MIYAKE A, Ngo MH, Wulandari S, Shimojima M, et al
    Convergent evolution of antiviral machinery derived from endogenous retrovirus truncated envelope genes in multiple species.
    Proc Natl Acad Sci U S A. 2022;119:e2114441119.
    PubMed     Abstract available


  35. DONG H, Ham JD, Hu G, Xie G, et al
    Memory-like NK cells armed with a neoepitope-specific CAR exhibit potent activity against NPM1 mutated acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2022;119:e2122379119.
    PubMed     Abstract available


    April 2022
  36. HOANG DH, Zhao D, Branciamore S, Maestrini D, et al
    MicroRNA networks in FLT3-ITD acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2022;119:e2112482119.
    PubMed     Abstract available


  37. DAI YT, Zhang F, Fang H, Li JF, et al
    Transcriptome-wide subtyping of pediatric and adult T cell acute lymphoblastic leukemia in an international study of 707 cases.
    Proc Natl Acad Sci U S A. 2022;119:e2120787119.
    PubMed     Abstract available


    March 2022
  38. CHAN LH, Yan Q
    Awakening KDM5B to defeat leukemia.
    Proc Natl Acad Sci U S A. 2022;119:e2202245119.
    PubMed    


  39. REN Z, Kim A, Huang YT, Pi WC, et al
    A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  40. PEPE F, Rassenti LZ, Pekarsky Y, Labanowska J, et al
    A large fraction of trisomy 12, 17p(-), and 11q(-) CLL cases carry unidentified microdeletions of miR-15a/16-1.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  41. GUO B, Pomicter AD, Li F, Bhatt S, et al
    Trident cold atmospheric plasma blocks three cancer survival pathways to overcome therapy resistance.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  42. FERRARO F, Miller CA, Christensen KA, Helton NM, et al
    Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  43. LYCZEK A, Berger BT, Rangwala AM, Paung Y, et al
    Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  44. GARCIA-GARCIA A, Klein T, Born G, Hilpert M, et al
    Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  45. BENSBERG M, Rundquist O, Selimovic A, Lagerwall C, et al
    TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  46. YANG L, Yin J, Wu J, Qiao L, et al
    Engineering genetic devices for in vivo control of therapeutic T cell activity triggered by the dietary molecule resveratrol.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  47. WU A, Zhi J, Tian T, Cihan A, et al
    DOT1L complex regulates transcriptional initiation in human erythroleukemic cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  48. O'SULLIVAN D, Stanczak MA, Villa M, Uhl FM, et al
    Fever supports CD8(+) effector T cell responses by promoting mitochondrial translation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  49. CHRETIEN AS, Devillier R, Granjeaud S, Cordier C, et al
    High-dimensional mass cytometry analysis of NK cell alterations in AML identifies a subgroup with adverse clinical outcome.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  50. RIVERA OD, Mallory MJ, Quesnel-Vallieres M, Chatrikhi R, et al
    Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  51. KU Y, Park JH, Cho R, Lee Y, et al
    Noncanonical immune response to the inhibition of DNA methylation by Staufen1 via stabilization of endogenous retrovirus RNAs.
    Proc Natl Acad Sci U S A. 2021;118:e2016289118.
    PubMed     Abstract available


  52. OWEN N, Minko IG, Moellmer SA, Cammann SK, et al
    Enhanced cytarabine-induced killing in OGG1-deficient acute myeloid leukemia cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  53. LOVAT F, Gasparini P, Nigita G, Larkin K, et al
    Loss of expression of both miR-15/16 loci in CML transition to blast crisis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  54. WU K, Huynh KQ, Lu I, Moustakim M, et al
    Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  55. PAN L, Hong C, Chan LN, Xiao G, et al
    PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  56. LEE YL, Ito K, Pi WC, Lin IH, et al
    Mediator subunit MED1 is required for E2A-PBX1-mediated oncogenic transcription and leukemic cell growth.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


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