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Adult Acute Lymphoblastic Leukemia: 2025 Update on Diagnosis, Therapy, and
Monitoring.
Am J Hematol. 2025 May 16. doi: 10.1002/ajh.27708.
PubMed
Abstract available
Optimal Depth of the Treatment Response Before Allogeneic Hematopoietic
Transplantation for Chronic Myeloid Leukemia in Chronic Phase.
Am J Hematol. 2025 May 12. doi: 10.1002/ajh.27706.
PubMed
TP53 -Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk-Stratification,
and Management.
Am J Hematol. 2025;100 Suppl 4.
PubMed
Abstract available
Inotuzumab therapy resulted in molecular remission of relapsed/resistant B-cell
acute lymphoblastic leukemia with BCR::ABL1 Lys404Glu mutation.
Ann Hematol. 2025 May 16. doi: 10.1007/s00277-025-06385.
PubMed
Abstract available
Rituximab efficacy for minimal residual disease eradication in
philadelphia-negative acute lymphoblastic leukemia CD20.
Ann Hematol. 2025 May 16. doi: 10.1007/s00277-025-06332.
PubMed
Abstract available
Prognostic value of CD47 overexpression measured by flow cytometry in acute
myeloid leukemia.
Ann Hematol. 2025 May 15. doi: 10.1007/s00277-025-06401.
PubMed
Abstract available
Connectivity-map unveils Gemcitabine's efficacy in overcoming nelarabine
resistance in T-cell acute lymphoblastic leukemia.
Biochem Biophys Res Commun. 2025;769:151971.
PubMed
Abstract available
FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable
for human hematopoietic stem cells.
Blood. 2025 Jan 22:blood.2024025886. doi: 10.1182/blood.2024025886.
PubMed
Abstract available
How I Treat: Revisiting the myth of second remission in acute lymphoblastic
leukemia in the era of immunotherapy.
Blood. 2025 May 12:blood.2024027267. doi: 10.1182/blood.2024027267.
PubMed
Abstract available
Transcriptional remodeling shapes therapeutic vulnerability to necroptosis in
acute lymphoblastic leukemia.
Blood. 2025 May 13:blood.2025028938. doi: 10.1182/blood.2025028938.
PubMed
Abstract available
Adult T-cell leukemia/lymphoma coexistent with immune dysregulation-associated
EBV+ lymphoproliferative disorder.
Blood. 2025;145:2396.
PubMed
A phase 2 Trial of CHOP with Anti-CCR4 Antibody Mogamulizumab for older Patients
with Adult T-Cell Leukemia/Lymphoma.
Blood. 2025 May 15:blood.2024027902. doi: 10.1182/blood.2024027902.
PubMed
Abstract available
Addition of mycophenolate mofetil to a calcineurin inhibitor and post-transplant
cyclophosphamide results in lower incidence of extensive chronic
graft-versus-host disease in HLA-matched allogeneic hematopoietic stem cell
transplantation for acute mye
Bone Marrow Transplant. 2025 May 13. doi: 10.1038/s41409-025-02610.
PubMed
Abstract available
Survival outcomes between haploidentical stem cell transplantation and
chemotherapy for blastic plasmacytoid dendritic cell neoplasm.
Bone Marrow Transplant. 2025 Feb 12. doi: 10.1038/s41409-025-02528.
PubMed
Abstract available
The IKZF1 N159S mutation is associated with poor outcome and a distinct molecular
profile in adult patients with AML.
Br J Haematol. 2025;206:1373-1379.
PubMed
Abstract available
Therapeutic drug monitoring of imatinib in paediatric chronic myeloid leukaemia:
Data from a real-world setting.
Br J Haematol. 2025;206:1397-1405.
PubMed
Abstract available
Monitoring the KMT2A gene post-chemotherapy independently predicts the relapse
and survival risk after allogeneic haematopoietic stem cell transplantation.
Br J Haematol. 2025;206:1418-1429.
PubMed
Abstract available
RNA-sequencing: A reliable tool to unveil transcriptional landscape of paediatric
B-other acute lymphoblastic leukaemia.
Br J Haematol. 2025;206:1355-1365.
PubMed
Abstract available
The mechanism of EZH2/H3K27me3 downregulating CXCL10 to affect CD8(+) T cell
exhaustion to participate in the transformation from myelodysplastic syndrome to
acute myeloid leukaemia.
Br J Haematol. 2025;206:1335-1349.
PubMed
Abstract available
Cord blood transplants: Advancing leukaemia treatments and addressing health
disparities.
Br J Haematol. 2025;206:1312-1314.
PubMed
Abstract available
Has the time for treatment-free remission in Philadelphia chromosome-positive
acute lymphoblastic leukemia arrived?
Cancer. 2025;131:e35880.
PubMed
Modeling the PAX5P80R Mutation Reveals HIF2alpha Activation as a Common Feature and
Therapeutic Target in B-Cell Acute Lymphoblastic Leukemia.
Cancer Res. 2025 May 12. doi: 10.1158/0008-5472.CAN-24-1698.
PubMed
Abstract available
A Machine Learning-Based Strategy Predicts Selective and Synergistic Drug
Combinations for Relapsed Acute Myeloid Leukemia.
Cancer Res. 2025 May 12. doi: 10.1158/0008-5472.CAN-24-3840.
PubMed
Abstract available
Notch1 activation and inhibition in T cell acute lymphoblastic leukemia subtypes.
Exp Hematol. 2025 May 8:104771. doi: 10.1016/j.exphem.2025.104771.
PubMed
Abstract available
High-Dose Methotrexate in Children and Young Adults With ALL and Lymphoblastic
Lymphoma: Results of the Randomized Phase III Study UKALL 2011.
J Clin Oncol. 2025 Apr 7:JCO2401851. doi: 10.1200/JCO-24-01851.
PubMed
Abstract available
Comparison of Consolidation Strategies for Pediatric Patients With Acute Myeloid
Leukemia: Results of the Randomized GATLA 8-LMA-P'07 Trial.
J Pediatr Hematol Oncol. 2025 May 12. doi: 10.1097/MPH.0000000000003028.
PubMed
Abstract available
Intake of benzodiazepines in treatment naive chronic lymphocytic leukemia
patients is associate with a shorter time to first treatment.
Leuk Lymphoma. 2025 May 15:1-6. doi: 10.1080/10428194.2025.2504155.
PubMed
Abstract available
Clinical impact of tyrosine kinases related mutations in NPM1 mutated acute
myeloid leukaemia: A report from the Northern Italy Leukaemia Group (NILG)
multicentre randomized trial 02/06.
Leuk Res. 2025;153:107702.
PubMed
Abstract available
The evolving landscape of epigenetic target molecules and therapies in myeloid
cancers: focus on acute myeloid leukemia and myeloproliferative neoplasms.
Leukemia. 2025 May 15. doi: 10.1038/s41375-025-02639.
PubMed
Abstract available
Acute myeloid leukemia stem cells remodel the bone marrow niche via
TGF-beta-activated Alcam(+) bone lining cells, creating a self-sustaining
environment.
Leukemia. 2025 May 13. doi: 10.1038/s41375-025-02640.
PubMed
Heterogeneity of IKZF1 genomic alterations and risk of relapse in childhood
B-cell precursor acute lymphoblastic leukemia.
Leukemia. 2025 May 13. doi: 10.1038/s41375-025-02633.
PubMed
Abstract available
Characteristics and outcomes of newly diagnosed acute myeloid Leukemia with KMT2A
rearrangements.
Leukemia. 2025 May 9. doi: 10.1038/s41375-025-02634.
PubMed
Abstract available
Ph-Positive Acute Lymphoblastic Leukemia - 25 Years of Progress.
N Engl J Med. 2025;392:1941-1952.
PubMed
WTAP-mediated m(6)A methylation of PHF19 facilitates cell cycle progression by
remodeling the accessible chromatin landscape in t(8;21) AML.
Oncogene. 2025;44:1504-1516.
PubMed
Abstract available
SNX10 regulates the proliferation, apoptosis and cell cycle of acute B
lymphoblastic leukemia cells via the PI3K/Akt signaling pathway.
Oncol Rep. 2025;54:78.
PubMed
Abstract available
Discovery of an LSD1 PROTAC degrader.
Proc Natl Acad Sci U S A. 2025;122:e2425812122.
PubMed
Abstract available
Thank you for your interest in scientific medicine.