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Articles published in J Biol Chem

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Single Articles


    July 2020
  1. STEINAUER N, Guo C, Zhang J
    The transcriptional corepressor CBFA2T3 inhibits all-trans-retinoic acid-induced myeloid gene expression and differentiation in acute myeloid leukemia.
    J Biol Chem. 2020;295:8887-8900.
    PubMed     Abstract available


    May 2020
  2. WANG H, Shah CA, Hu L, Huang W, et al
    An aberrantly sustained emergency granulopoiesis response accelerates post chemotherapy relapse in MLL1-rearranged acute myeloid leukemia in mice.
    J Biol Chem. 2020 May 28. pii: RA120.013206. doi: 10.1074/jbc.RA120.013206.
    PubMed     Abstract available


  3. STEINAUER N, Guo C, Zhang J
    The transcriptional corepressor CBFA2T3 inhibits all-trans retinoic acid-induced myeloid gene expression and differentiation in acute myeloid leukemia.
    J Biol Chem. 2020 May 20. pii: RA120.013042. doi: 10.1074/jbc.RA120.013042.
    PubMed     Abstract available


  4. SALUSTIANO EJ, da Costa KM, Freire-de-Lima L, Mendonca-Previato L, et al
    Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differentially modulating ABC transporters in chronic myeloid leukemias.
    J Biol Chem. 2020;295:6457-6471.
    PubMed     Abstract available


    April 2020
  5. WIST M, Meier L, Gutman O, Haas J, et al
    Noncatalytic Bruton's tyrosine kinase activates PLCgamma2 variants mediating ibrutinib resistance in human chronic lymphocytic leukemia cells.
    J Biol Chem. 2020;295:5717-5736.
    PubMed     Abstract available


  6. GHAZALY EA, Miraki-Moud F, Smith P, Gnanaranjan C, et al
    Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function.
    J Biol Chem. 2020;295:5496-5508.
    PubMed     Abstract available


    March 2020
  7. GUO C, Li J, Steinauer N, Wong M, et al
    Histone deacetylase 3 preferentially binds and collaborates with the transcription factor RUNX1 to repress AML1-ETO-dependent transcription in t(8;21) AML.
    J Biol Chem. 2020;295:4212-4223.
    PubMed     Abstract available


  8. WIST M, Meier L, Gutman O, Haas J, et al
    Non-catalytic Bruton's tyrosine kinase activates PLCgamma2 variants mediating ibrutinib resistance in human chronic lymphocytic leukemia cells.
    J Biol Chem. 2020 Mar 17. pii: RA119.011946. doi: 10.1074/jbc.RA119.011946.
    PubMed     Abstract available


  9. GHAZALY EA, Miraki-Moud F, Smith P, Gnanaranjan C, et al
    Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function.
    J Biol Chem. 2020 Mar 11. pii: RA119.010467. doi: 10.1074/jbc.RA119.010467.
    PubMed     Abstract available


    August 2019
  10. DEMBITZ V, Tomic B, Kodvanj I, Simon JA, et al
    The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 kinase via pyrimidine depletion.
    J Biol Chem. 2019 Aug 20. pii: RA119.009396. doi: 10.1074/jbc.RA119.009396.
    PubMed     Abstract available


  11. DUVAL R, Bui LC, Mathieu C, Nian Q, et al
    Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling.
    J Biol Chem. 2019;294:12483-12494.
    PubMed     Abstract available


  12. KINDERMANN B, Valkova C, Kramer A, Perner B, et al
    The nuclear pore proteins Nup88/214 and T-cell acute lymphatic leukemia-associated NUP214 fusion proteins regulate Notch signaling.
    J Biol Chem. 2019;294:11741-11750.
    PubMed     Abstract available


    June 2019
  13. ZHANG X, Tu H, Yang Y, Jiang X, et al
    Bone marrow-derived mesenchymal stromal cells promote resistance to tyrosine kinase inhibitors in chronic myeloid leukemia via the IL-7/JAK1/STAT5 pathway.
    J Biol Chem. 2019 Jun 24. pii: RA119.008037. doi: 10.1074/jbc.RA119.008037.
    PubMed     Abstract available


    March 2019
  14. SANDOVAL JE, Huang YH, Muise A, Goodell MA, et al
    Mutations in the DNMT3A DNA methyltransferase in acute myeloid leukemia patients cause both loss and gain of function and differential regulation by protein partners.
    J Biol Chem. 2019;294:4898-4910.
    PubMed     Abstract available


    February 2019
  15. SONG P, Yang S, Hua H, Zhang H, et al
    The regulatory protein GADD34 inhibits TRAIL-induced apoptosis via TRAF6/ERK-dependent stabilization of myeloid cell leukemia 1 in liver cancer cells.
    J Biol Chem. 2019 Feb 19. pii: RA118.006029. doi: 10.1074/jbc.RA118.006029.
    PubMed     Abstract available


    November 2018
  16. NIE M, Wang Y, Guo C, Li X, et al
    CARM1-mediated methylation of protein arginine methyltransferase 5 represses human gamma-globin gene expression in erythroleukemia cells.
    J Biol Chem. 2018;293:17454-17463.
    PubMed     Abstract available


    October 2018
  17. DUGGIMPUDI S, Kloetgen A, Maney SK, Munch PC, et al
    Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling.
    J Biol Chem. 2018;293:15359-15369.
    PubMed     Abstract available


    September 2018
  18. WU W, Hatterschide J, Syu YC, Cantara WA, et al
    Human T-cell leukemia virus type 1 Gag domains have distinct RNA-binding specificities with implications for RNA packaging and dimerization.
    J Biol Chem. 2018 Sep 14. pii: RA118.005531. doi: 10.1074/jbc.RA118.005531.
    PubMed     Abstract available


    June 2018
  19. MIYANOKOSHI M, Yokosawa T, Wakasugi K
    Tryptophanyl-tRNA synthetase mediates high-affinity tryptophan uptake into human cells.
    J Biol Chem. 2018;293:8428-8438.
    PubMed     Abstract available


    May 2018
  20. BRUINSMA S, James DJ, Quintana Serrano M, Esquibel J, et al
    Small molecules that inhibit the late stage of Munc13-4-dependent secretory granule exocytosis in mast cells.
    J Biol Chem. 2018;293:8217-8229.
    PubMed     Abstract available


  21. ZHANG H, Coblentz C, Watanabe-Smith K, Means S, et al
    Gain-of-function mutations in granulocyte colony-stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation.
    J Biol Chem. 2018;293:7387-7396.
    PubMed     Abstract available


    March 2018
  22. CHERIAN MA, Olson S, Sundaramoorthi H, Cates K, et al
    An activating mutation of interferon regulatory factor 4 (IRF4) in adult T cell leukemia.
    J Biol Chem. 2018 Mar 14. pii: RA117.000164. doi: 10.1074/jbc.RA117.000164.
    PubMed     Abstract available


    September 2017
  23. BROWN LM, Hanna DT, Khaw SL, Ekert PG, et al
    Dysregulation of BCL-2 family proteins by leukemia fusion genes.
    J Biol Chem. 2017;292:14325-14333.
    PubMed     Abstract available


    August 2017
  24. HIRBAWI J, Bialkowska K, Bledzka KM, Liu J, et al
    The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.
    J Biol Chem. 2017;292:14258-14269.
    PubMed     Abstract available


    February 2017
  25. QIU Y, Zhang Y, Hu N, Dong F, et al
    A Truncated Granulocyte Colony-stimulating Factor Receptor (G-CSFR) Inhibits Apoptosis Induced by Neutrophil Elastase G185R Mutant: IMPLICATION FOR UNDERSTANDING CSF3R GENE MUTATIONS IN SEVERE CONGENITAL NEUTROPENIA.
    J Biol Chem. 2017;292:3496-3505.
    PubMed     Abstract available


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