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Articles published in Cancer Res

Retrieve available abstracts of 68 articles:
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    July 2021
  1. MAIFREDE S, Le BV, Nieborowska-Skorska M, Golovine K, et al
    TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors.
    Cancer Res. 2021 Jul 2. pii: 0008-5472.CAN-20-3761.
    PubMed     Abstract available

    February 2021
  2. O'HAGAN HM, Rassool FV, Nephew KP
    How Epigenetic Therapy Beats Adverse Genetics in Monosomy Karyotype AML.
    Cancer Res. 2021;81:813-815.
    PubMed     Abstract available

  3. GREVE G, Schuler J, Gruning BA, Berberich B, et al
    Decitabine Induces Gene Derepression on Monosomic Chromosomes: In Vitro and In Vivo Effects in Adverse-Risk Cytogenetics AML.
    Cancer Res. 2021;81:834-846.
    PubMed     Abstract available

    January 2021
  4. DING H, Vincelette ND, McGehee CD, Kohorst MA, et al
    CDK2-mediated upregulation of TNFa as a mechanism of selective cytotoxicity in acute leukemia.
    Cancer Res. 2021 Jan 7. pii: 0008-5472.CAN-20-1504.
    PubMed     Abstract available

  5. TAMIRO F, Weng AP, Giambra V
    Targeting leukemia-initiating cells in acute lymphoblastic leukemia (ALL).
    Cancer Res. 2021 Jan 7. pii: 0008-5472.CAN-20-2571.
    PubMed     Abstract available

    December 2020
  6. ORAVECZ-WILSON K, Rossi C, Zajac C, Sun Y, et al
    ATG5-dependent autophagy uncouples T cell proliferative and effector functions and separates graft-versus-host disease from graft-versus-leukemia.
    Cancer Res. 2020 Dec 4. pii: 0008-5472.CAN-20-1346.
    PubMed     Abstract available

    October 2020
  7. SAINT FLEUR-LOMINY S, Evensen NA, Bhatla T, Sethia G, et al
    Evolution of the epigenetic landscape in childhood B acute lymphoblastic leukemia and its role in drug resistance.
    Cancer Res. 2020 Oct 16. pii: 0008-5472.CAN-20-1145.
    PubMed     Abstract available

    September 2020
  8. STIEHL T, Wang W, Lutz C, Marciniak-Czochra A, et al
    Mathematical Modeling Provides Evidence for Niche Competition in Human AML and Serves as a Tool to Improve Risk Stratification.
    Cancer Res. 2020;80:3983-3992.
    PubMed     Abstract available

  9. NGUYEN CH, Schlerka A, Grandits AM, Koller E, et al
    IL2RA promotes aggressiveness and stem cell-related properties of acute myeloid leukemia.
    Cancer Res. 2020 Sep 1. pii: 0008-5472.CAN-20-0531.
    PubMed     Abstract available

  10. TOHUMEKEN S, Baur R, Bottcher M, Stoll A, et al
    Palmitoylated Proteins on AML-Derived Extracellular Vesicles Promote Myeloid-Derived Suppressor Cell Differentiation via TLR2/Akt/mTOR Signaling.
    Cancer Res. 2020;80:3663-3676.
    PubMed     Abstract available

    August 2020
    Predicting Cancer Evolution Using Cell State Dynamics.
    Cancer Res. 2020;80:3072-3073.
    PubMed     Abstract available

    July 2020
  12. YANG F, Feng W, Wang H, Wang L, et al
    Monocyte-derived leukemia-associated macrophages facilitate extramedullary distribution of T-cell acute lymphoblastic leukemia cells.
    Cancer Res. 2020 Jul 10. pii: 0008-5472.CAN-20-0034.
    PubMed     Abstract available

    June 2020
  13. HAHNEL T, Baldow C, Guilhot J, Guilhot F, et al
    Model-Based Inference and Classification of Immunologic Control Mechanisms from TKI Cessation and Dose Reduction in Patients with CML.
    Cancer Res. 2020;80:2394-2406.
    PubMed     Abstract available

  14. SUN L, Li CW, Chung EM, Yang R, et al
    Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity.
    Cancer Res. 2020;80:2298-2310.
    PubMed     Abstract available

    May 2020
  15. ROCKNE RC, Branciamore S, Qi J, Frankhouser DE, et al
    State-transition analysis of time-sequential gene expression identifies critical points that predict development of acute myeloid leukemia.
    Cancer Res. 2020 May 15. pii: 0008-5472.CAN-20-0354.
    PubMed     Abstract available

    January 2020
  16. KLINGER M, Zugmaier G, Nagele V, Goebeler ME, et al
    Adhesion of T Cells to Endothelial Cells Facilitates Blinatumomab-Associated Neurologic Adverse Events.
    Cancer Res. 2020;80:91-101.
    PubMed     Abstract available

    December 2019
  17. ROBINSON AJ, Hopkins GL, Rastogi N, Hodges M, et al
    Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3.
    Cancer Res. 2019 Dec 20. pii: 0008-5472.CAN-19-1920.
    PubMed     Abstract available

  18. SHU Y, Wang Y, Lv WQ, Peng DY, et al
    ARRB1-promoted NOTCH1 degradation is suppressed by oncomiR miR-223 in T cell acute lymphoblastic leukemia.
    Cancer Res. 2019 Dec 10. pii: 0008-5472.CAN-19-1471.
    PubMed     Abstract available

    November 2019
  19. SACHS K, Sarver AL, Noble-Orcutt KE, LaRue RS, et al
    Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia.
    Cancer Res. 2019 Nov 29. pii: 0008-5472.CAN-18-2932.
    PubMed     Abstract available

  20. KONDO T, Ando M, Nagai N, Tomisato W, et al
    The NOTCH-FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory-like CAR-T Cells.
    Cancer Res. 2019 Nov 25. pii: 0008-5472.CAN-19-1196.
    PubMed     Abstract available

    September 2019
  21. LY M, Rentas S, Vujovic A, Wong N, et al
    Diminished AHR signaling drives human acute myeloid leukemia stem cell maintenance.
    Cancer Res. 2019 Sep 13. pii: 0008-5472.CAN-19-0274.
    PubMed     Abstract available

    July 2019
  22. HOSSEINI M, Rezvani H, Aroua N, Bosc C, et al
    Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia.
    Cancer Res. 2019 Jul 29. pii: 0008-5472.CAN-19-0515.
    PubMed     Abstract available

  23. BURSLEM GM, Schultz AR, Bondeson DP, Eide CA, et al
    Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-mediated Targeted Protein Degradation.
    Cancer Res. 2019 Jul 16. pii: 0008-5472.CAN-19-1236.
    PubMed     Abstract available

  24. ROSS J, Rashkovan M, Fraszczak J, Joly Beauparlant C, et al
    Deletion of the Miz-1 POZ domain increases efficacy of cytarabine treatment in T- and B-ALL/lymphoma mouse models.
    Cancer Res. 2019 Jul 4. pii: 0008-5472.CAN-18-3038.
    PubMed     Abstract available

  25. DAS B, Pal B, Bhuyan R, Li H, et al
    MYC regulates the HIF-2alpha stemness pathway via Nanog and Sox2 to maintain self-renewal in cancer stem cells versus non-stem cancer cells.
    Cancer Res. 2019 Jul 2. pii: 0008-5472.CAN-18-2847.
    PubMed     Abstract available

    June 2019
  26. AQAQE N, Yassin M, Yassin AA, Ershaid N, et al
    An ERG enhancer-based reporter identifies leukemia cells with elevated leukemogenic potential driven by ERG-USP9X feed-forward regulation.
    Cancer Res. 2019 Jun 7. pii: 0008-5472.CAN-18-3215.
    PubMed     Abstract available

    May 2019
  27. RABE JL, Gardner L, Hunter R, Fonseca JA, et al
    IL-12 abrogates calcineurin-dependent immune evasion during leukemia progression.
    Cancer Res. 2019 May 29. pii: 0008-5472.CAN-18-3800.
    PubMed     Abstract available

  28. POLONEN P, Mehtonen J, Lin J, Liuksiala T, et al
    Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies.
    Cancer Res. 2019;79:2466-2479.
    PubMed     Abstract available

  29. HAN Z, Li Y, Zhang J, Liu J, et al
    Molecular Imaging of Deoxycytidine Kinase Activity Using Deoxycytidine-Enhanced CEST MRI.
    Cancer Res. 2019;79:2775-2783.
    PubMed     Abstract available

  30. BARTELS L, de Jong G, Gillissen MA, Yasuda E, et al
    A chemo-enzymatically linked bispecific antibody retargets T cells to a sialylated epitope on CD43 in acute myeloid leukemia.
    Cancer Res. 2019 May 7. pii: 0008-5472.CAN-18-0189.
    PubMed     Abstract available

    March 2019
  31. DIAZ-FLORES E, Comeaux EQ, Kim KL, Melnik EM, et al
    BCL-2 is a Therapeutic Target For Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.
    Cancer Res. 2019 Mar 12. pii: 0008-5472.CAN-18-0236.
    PubMed     Abstract available

    February 2019
  32. JIA B, Zhao C, Rakszawski KL, Claxton DF, et al
    Eomes+T-betlow CD8+ T cells are functionally impaired and are associated with poor clinical outcome in patients with acute myeloid leukemia (AML).
    Cancer Res. 2019 Feb 1. pii: 0008-5472.CAN-18-3107.
    PubMed     Abstract available

    January 2019
  33. CARTER BZ, Mak PY, Wang X, Tao W, et al
    An ARC-regulated IL1beta/Cox-2/PGE2/beta-catenin/ARC circuit controls leukemia-microenvironment interactions and confers drug resistance in AML.
    Cancer Res. 2019 Jan 23. pii: 0008-5472.CAN-18-0921.
    PubMed     Abstract available

  34. DADASHIAN EL, McAuley EM, Liu D, Shaffer AL 3rd, et al
    TLR Signaling Is Activated in Lymph Node-Resident CLL Cells and Is Only Partially Inhibited by Ibrutinib.
    Cancer Res. 2019;79:360-371.
    PubMed     Abstract available

  35. SULIMA SO, Kampen KR, Vereecke S, Pepe D, et al
    Ribosomal Lesions Promote Oncogenic Mutagenesis.
    Cancer Res. 2019;79:320-327.
    PubMed     Abstract available

  36. HU T, Chong Y, Lu S, Qin H, et al
    Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice.
    Cancer Res. 2019;79:114-124.
    PubMed     Abstract available

    December 2018
  37. TAKAM KAMGA P, Dal Collo G, Midolo M, Adamo A, et al
    Inhibition of Notch signaling enhances chemosensitivity in B cell precursor acute lymphoblastic leukemia.
    Cancer Res. 2018 Dec 18. pii: 0008-5472.CAN-18-1617.
    PubMed     Abstract available

  38. WARDA W, Larosa F, Neto Da Rocha M, Trad R, et al
    CML hematopoietic stem cells expressing IL-1RAP can be targeted by chimeric antigen receptor (CAR)-engineered T cells.
    Cancer Res. 2018 Dec 4. pii: 0008-5472.CAN-18-1078.
    PubMed     Abstract available

    October 2018
  39. SPICIARICH DR, Oh ST, Foley A, Hughes SB, et al
    A novel germline variant in CSF3R reduces N-glycosylation and exerts potent oncogenic effects in leukemia.
    Cancer Res. 2018 Oct 22. pii: 0008-5472.CAN-18-1638.
    PubMed     Abstract available

  40. DE GRANDIS M, Mancini SJC, Vey N, Aurrand-Lions M, et al
    JAM-C Expression as a Biomarker to Predict Outcome of Patients with Acute Myeloid Leukemia-Response.
    Cancer Res. 2018 Oct 17. pii: 0008-5472.CAN-18-0834.

  41. VON BONIN M, Moll K, Kramer M, Oelschlagel U, et al
    JAM-C Expression as a Biomarker to Predict Outcome of Patients with Acute Myeloid Leukemia-Letter.
    Cancer Res. 2018 Oct 17. pii: 0008-5472.CAN-18-0642.

    September 2018
  42. DUQUE-AFONSO J, Lin CH, Han K, Morgens DW, et al
    CBP modulates sensitivity to dasatinib in pre-BCR+ acute lymphoblastic leukemia.
    Cancer Res. 2018 Sep 27. pii: 0008-5472.CAN-18-1703.
    PubMed     Abstract available

  43. Correction: Carbonyl Reductase 1 Offers a Novel Therapeutic Target to Enhance Leukemia Treatment by Arsenic Trioxide.
    Cancer Res. 2018;78:5464.

  44. SOEGAARD SH, Rostgaard K, Skogstrand K, Wiemels JL, et al
    Neonatal Inflammatory Markers Are Associated with Childhood B-cell Precursor Acute Lymphoblastic Leukemia.
    Cancer Res. 2018;78:5458-5463.
    PubMed     Abstract available

    August 2018
  45. INSELMANN S, Wang Y, Saussele S, Fritz L, et al
    Development, function and clinical significance of plasmacytoid dendritic cells in chronic myeloid leukemia.
    Cancer Res. 2018 Aug 30. pii: 0008-5472.CAN-18-1477.
    PubMed     Abstract available

  46. MINIERI V, De Dominici M, Porazzi P, Mariani SA, et al
    Targeting STAT5 or STAT5-regulated pathways suppresses leukemogenesis of Ph+ acute lymphoblastic leukemia.
    Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0195.
    PubMed     Abstract available

    June 2018
  47. OSUMI T, Tsujimoto SI, Tamura M, Uchiyama M, et al
    Recurrent RARB Translocations in Acute Promyelocytic Leukemia lacking RARA Translocation.
    Cancer Res. 2018 Jun 19. pii: 0008-5472.CAN-18-0840.
    PubMed     Abstract available

    May 2018
  48. HU T, Chong Y, Lu S, Wang R, et al
    MicroRNA 339 promotes development of Stem Cell Leukemia/Lymphoma syndrome via downregulation of the BCL2L11 and BAX pro-apoptotic genes.
    Cancer Res. 2018 May 7. pii: 0008-5472.CAN-17-4049.
    PubMed     Abstract available

    April 2018
  49. ZHOU M, Zhou K, Cheng L, Chen X, et al
    MBD2 Ablation Impairs Lymphopoiesis and Impedes Progression and Maintenance of T-ALL.
    Cancer Res. 2018;78:1632-1642.
    PubMed     Abstract available

    March 2018

  50. Correction: The Multikinase Inhibitor Sorafenib Potentiates TRAIL Lethality in Human Leukemia Cells in Association with Mcl-1 and cFLIPL Down-regulation.
    Cancer Res. 2018;78:1575.

    February 2018
  51. HE L, Tang J, Andersson EI, Timonen S, et al
    Patient-customized Drug Combination Prediction and Testing for T-cell Prolymphocytic Leukemia Patients.
    Cancer Res. 2018 Feb 26. pii: 0008-5472.CAN-17-3644.
    PubMed     Abstract available

    January 2018
  52. LIU C, Nie D, Li J, Du X, et al
    Antitumor effects of blocking protein neddylation in T315I-BCR-ABL leukemia cells and leukemia stem cells.
    Cancer Res. 2018 Jan 10. pii: 0008-5472.CAN-17-1733.
    PubMed     Abstract available

    December 2017
  53. DE DOMINICI M, Porazzi P, Soliera AR, Mariani SA, et al
    Targeting CDK6 and BCL2 exploits the "MYB addiction" of Ph+ acute lymphoblastic leukemia.
    Cancer Res. 2017 Dec 12. pii: 0008-5472.CAN-17-2644.
    PubMed     Abstract available

  54. NOBREGA-PEREIRA S, Caiado F, Carvalho T, Matias I, et al
    VEGFR-2-mediated reprogramming of mitochondrial metabolism regulates the sensitivity of acute myeloid leukemia to chemotherapy.
    Cancer Res. 2017 Dec 11. pii: 0008-5472.CAN-17-1166.
    PubMed     Abstract available

    November 2017
  55. LE SOMMER S, Morrice N, Pesaresi M, Thompson D, et al
    Deficiency in protein tyrosine phosphatase PTP1B shortens lifespan and leads to development of acute leukemia.
    Cancer Res. 2017 Nov 9. pii: canres.0946.2017.
    PubMed     Abstract available

    October 2017
  56. BRUNER JK, Ma HS, Li L, Qin ACR, et al
    Adaptation to TKI Treatment Reactivates ERK Signaling in Tyrosine Kinase-Driven Leukemias and Other Malignancies.
    Cancer Res. 2017;77:5554-5563.
    PubMed     Abstract available

  57. SABA NS, Wong DH, Tanios G, Iyer JR, et al
    MALT1 inhibition is efficacious in both naive and ibrutinib-resistant chronic lymphocytic leukemia.
    Cancer Res. 2017 Oct 9. pii: canres.2485.2017.
    PubMed     Abstract available

    September 2017
  58. DE GRANDIS M, Bardin F, Fauriat C, Zemmour C, et al
    JAM-C identifies Src family kinase-activated leukemia-initiating cells and predicts poor prognosis in acute myeloid leukemia.
    Cancer Res. 2017 Sep 28. pii: canres.1223.2017.
    PubMed     Abstract available

  59. JING W, Gershan JA, Holzhauer S, Weber J, et al
    T cells deficient in diacylglycerol kinase-zeta are resistant to PD-1 inhibition and help create persistent host immunity to leukemia.
    Cancer Res. 2017 Sep 15. pii: canres.1309.2017.
    PubMed     Abstract available

    August 2017
  60. ZHANG H, Means S, Schultz AR, Watanabe-Smith K, et al
    Unpaired Extracellular Cysteine Mutations of CSF3R Mediate Gain or Loss of Function.
    Cancer Res. 2017;77:4258-4267.
    PubMed     Abstract available

  61. HOU P, Wu C, Wang Y, Qi R, et al
    A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.
    Cancer Res. 2017;77:4402-4413.
    PubMed     Abstract available

    June 2017
  62. GREEN AM, Budagyan K, Hayer KE, Reed MA, et al
    Cytosine deaminase APOBEC3A sensitizes leukemia cells to inhibition of the DNA replication checkpoint.
    Cancer Res. 2017 Jun 27. pii: canres.3394.2016.
    PubMed     Abstract available

  63. TAMAI H, Yamaguchi H, Miyake K, Takatori M, et al
    Amlexanox downregulates S100A6 to sensitize KMT2A/AFF1-positive acute lymphoblastic leukemia to TNF-alpha treatment.
    Cancer Res. 2017 Jun 23. pii: canres.2974.2016.
    PubMed     Abstract available

  64. RODRIGUEZ-HERNANDEZ G, Hauer J, Martin-Lorenzo A, Schafer D, et al
    Infection exposure promotes ETV6-RUNX1 precursor B cell leukemia via impaired H3K4 demethylases.
    Cancer Res. 2017 Jun 19. pii: canres.0701.2017.
    PubMed     Abstract available

    April 2017

  65. Correction: Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia.
    Cancer Res. 2017;77:2174.

  66. DRENBERG CD, Gibson AA, Pounds SB, Shi L, et al
    OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues.
    Cancer Res. 2017;77:2102-2111.
    PubMed     Abstract available

  67. VALERIO DG, Xu H, Chen CW, Hoshii T, et al
    Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.
    Cancer Res. 2017;77:1753-1762.
    PubMed     Abstract available

    January 2017
  68. EISFELD AK, Kohlschmidt J, Mrozek K, Volinia S, et al
    Mutational Landscape and Gene Expression Patterns in Adult Acute Myeloid Leukemias with Monosomy 7 as a Sole Abnormality.
    Cancer Res. 2017;77:207-218.
    PubMed     Abstract available

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