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Articles published in Proc Natl Acad Sci U S A

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Single Articles


    May 2022
  1. SLAVIN P, Sebbane F
    Emergence and spread of ancestral Yersinia pestis in Late-Neolithic and Bronze-Age Eurasia, ca. 5,000 to 1,500 y B.P.
    Proc Natl Acad Sci U S A. 2022;119:e2204044119.
    PubMed    


    April 2022
  2. ANDRADES VALTUENA A, Neumann GU, Spyrou MA, Musralina L, et al
    Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and ecology of plague.
    Proc Natl Acad Sci U S A. 2022;119:e2116722119.
    PubMed     Abstract available


  3. CHINER-OMS A, Lopez MG, Moreno-Molina M, Furio V, et al
    Gene evolutionary trajectories in Mycobacterium tuberculosis reveal temporal signs of selection.
    Proc Natl Acad Sci U S A. 2022;119:e2113600119.
    PubMed     Abstract available


  4. KOH EI, Oluoch PO, Ruecker N, Proulx MK, et al
    Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.
    Proc Natl Acad Sci U S A. 2022;119:e2201632119.
    PubMed     Abstract available


  5. AMOR DR, Gore J
    Fast growth can counteract antibiotic susceptibility in shaping microbial community resilience to antibiotics.
    Proc Natl Acad Sci U S A. 2022;119:e2116954119.
    PubMed     Abstract available


  6. HERNANDO-AMADO S, Laborda P, Valverde JR, Martinez JL, et al
    Mutational background influences P. aeruginosa ciprofloxacin resistance evolution but preserves collateral sensitivity robustness.
    Proc Natl Acad Sci U S A. 2022;119:e2109370119.
    PubMed     Abstract available


  7. DE BEI O, Marchetti M, Ronda L, Gianquinto E, et al
    Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
    Proc Natl Acad Sci U S A. 2022;119:e2116708119.
    PubMed     Abstract available


  8. LAUGHLIN ZT, Nandi S, Dey D, Zelinskaya N, et al
    50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
    Proc Natl Acad Sci U S A. 2022;119:e2120352119.
    PubMed     Abstract available


    March 2022
  9. PEREIRA MJ, Wager B, Garrigues RJ, Gerlach E, et al
    Lipoproteome screening of the Lyme disease agent identifies inhibitors of antibody-mediated complement killing.
    Proc Natl Acad Sci U S A. 2022;119:e2117770119.
    PubMed     Abstract available


  10. SUN X, Chi H
    Tregs tango with killer cells in acute infection.
    Proc Natl Acad Sci U S A. 2022;119:e2202400119.
    PubMed    


  11. CHEN J, Byun H, Liu R, Jung IJ, et al
    A commensal-encoded genotoxin drives restriction of Vibrio cholerae colonization and host gut microbiome remodeling.
    Proc Natl Acad Sci U S A. 2022;119:e2121180119.
    PubMed     Abstract available


  12. WANG X, Li P, Singh AK, Zhang X, et al
    Remodeling Yersinia pseudotuberculosis to generate a highly immunogenic outer membrane vesicle vaccine against pneumonic plague.
    Proc Natl Acad Sci U S A. 2022;119:e2109667119.
    PubMed     Abstract available


  13. OSMAN MM, Shanahan JK, Chu F, Takaki KK, et al
    The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence.
    Proc Natl Acad Sci U S A. 2022;119:e2122161119.
    PubMed     Abstract available


  14. DOLINA JS, Lee J, Moore EL, Hope JL, et al
    Developmentally distinct CD4(+) Treg lineages shape the CD8(+) T cell response to acute Listeria infection.
    Proc Natl Acad Sci U S A. 2022;119:e2113329119.
    PubMed     Abstract available


  15. KRISHNAN M, Choi J, Jang A, Choi S, et al
    Molecular mechanism underlying the TLR4 antagonistic and antiseptic activities of papiliocin, an insect innate immune response molecule.
    Proc Natl Acad Sci U S A. 2022;119:e2115669119.
    PubMed     Abstract available


    February 2022
  16. CHADDA A, Jensen D, Tomko EJ, Ruiz Manzano A, et al
    Mycobacterium tuberculosis DNA repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  17. TUFFS SW, Goncheva MI, Xu SX, Craig HC, et al
    Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  18. WANG L, Asare E, Shetty AC, Sanchez-Tumbaco F, et al
    Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  19. MEHDIRATTA K, Singh S, Sharma S, Bhosale RS, et al
    Kupyaphores are zinc homeostatic metallophores required for colonization of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  20. SUN S, Roth C, Floyd Averette A, Magwene PM, et al
    Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  21. COOPER C, Peterson EJR, Bailo R, Pan M, et al
    MadR mediates acyl CoA-dependent regulation of mycolic acid desaturation in mycobacteria.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  22. ERCOLI MF, Luu DD, Rim EY, Shigenaga A, et al
    Plant immunity: Rice XA21-mediated resistance to bacterial infection.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  23. SORGELOOS F, Peeters M, Hayashi Y, Borghese F, et al
    A case of convergent evolution: Several viral and bacterial pathogens hijack RSK kinases through a common linear motif.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  24. CHEN X, Schneewind O, Missiakas D
    Engineered human antibodies for the opsonization and killing of Staphylococcus aureus.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  25. VAN HAUWERMEIREN F, Van Opdenbosch N, Van Gorp H, de Vasconcelos N, et al
    Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  26. LEWIN GR, Stocke KS, Lamont RJ, Whiteley M, et al
    A quantitative framework reveals traditional laboratory growth is a highly accurate model of human oral infection.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  27. DAS S, Saqib M, Meng RC, Chittur SV, et al
    Hemochromatosis drives acute lethal intestinal responses to hyperyersiniabactin-producing Yersinia pseudotuberculosis.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  28. ZHANG Y, Fu J, Liu S, Wang L, et al
    Coxiella burnetii inhibits host immunity by a protein phosphatase adapted from glycolysis.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    December 2021
  29. LI J, Claudi B, Fanous J, Chicherova N, et al
    Tissue compartmentalization enables Salmonella persistence during chemotherapy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  30. MARGOLIS SR, Dietzen PA, Hayes BM, Wilson SC, et al
    The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemone Nematostella vectensis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  31. WOLINSKA KW, Vannier N, Thiergart T, Pickel B, et al
    Tryptophan metabolism and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    November 2021
  32. MARTIN MJ, Corey BW, Sannio F, Hall LR, et al
    Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  33. MONTGOMERY MG, Petri J, Spikes TE, Walker JE, et al
    Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  34. ALQARZAEE AA, Chaudhari SS, Islam MM, Kumar V, et al
    Staphylococcal ClpXP protease targets the cellular antioxidant system to eliminate fitness-compromised cells in stationary phase.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  35. BARNIER JP, Meyer J, Kolappan S, Bouzinba-Segard H, et al
    The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  36. SALAMAGA B, Kong L, Pasquina-Lemonche L, Lafage L, et al
    Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  37. PRICE SL, Vadyvaloo V, DeMarco JK, Brady A, et al
    Yersiniabactin contributes to overcoming zinc restriction during Yersinia pestis infection of mammalian and insect hosts.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2021
  38. GRISON CM, Lambey P, Jeannot S, Del Nero E, et al
    Molecular insights into mechanisms of GPCR hijacking by Staphylococcus aureus.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available



  39. Correction for Whitworth et al., Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  40. YU HB, Yang H, Allaire JM, Ma C, et al
    Vasoactive intestinal peptide promotes host defense against enteric pathogens by modulating the recruitment of group 3 innate lymphoid cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  41. SAECKER RM, Chen J, Chiu CE, Malone B, et al
    Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  42. LOPEZ-PEREZ M, Jayakumar JM, Grant TA, Zaragoza-Solas A, et al
    Ecological diversification reveals routes of pathogen emergence in endemic Vibrio vulnificus populations.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  43. QIN H, Zou Z, Anderson D, Sang Y, et al
    The transcription regulator BrsR serves as a network hub of natural competence protein-protein interactions in Streptococcus mutans.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  44. BARBIERI R
    Origin, transmission, and evolution of plague over 400 y in Europe.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  45. KESHARI RS, Popescu NI, Silasi R, Regmi G, et al
    Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  46. PEI S, Liljeros F, Shaman J
    Identifying asymptomatic spreaders of antimicrobial-resistant pathogens in hospital settings.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  47. JONES CS, Anderson AC, Clarke AJ
    Mechanism of Staphylococcus aureus peptidoglycan O-acetyltransferase A as an O-acyltransferase.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  48. BRAMANTI B, Wu Y, Yang R, Cui Y, et al
    Assessing the origins of the European Plagues following the Black Death: A synthesis of genomic, historical, and ecological information.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    August 2021
  49. LIM J, Lee JJ, Lee SK, Kim S, et al
    Phosphoenolpyruvate depletion mediates both growth arrest and drug tolerance of Mycobacterium tuberculosis in hypoxia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  50. GOUZY A, Healy C, Black KA, Rhee KY, et al
    Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  51. BARTH VC, Chauhan U, Zeng J, Su X, et al
    Mycobacterium tuberculosis VapC4 toxin engages small ORFs to initiate an integrated oxidative and copper stress response.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  52. LUIZET JB, Raymond J, Lacerda TLS, Barbieux E, et al
    The Brucella effector BspL targets the ER-associated degradation (ERAD) pathway and delays bacterial egress from infected cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  53. KADRY NA, Porsch EA, Shen H, St Geme JW 3rd, et al
    Immunization with HMW1 and HMW2 adhesins protects against colonization by heterologous strains of nontypeable Haemophilus influenzae.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  54. VINCENT CM, Dionne MS
    Disparate regulation of IMD signaling drives sex differences in infection pathology in Drosophila melanogaster.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  55. SHRESTHA E, Coulter JB, Guzman W, Ozbek B, et al
    Oncogenic gene fusions in nonneoplastic precursors as evidence that bacterial infection can initiate prostate cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    July 2021
  56. XI R, Montague J, Lin X, Lu C, et al
    Up-regulation of gasdermin C in mouse small intestine is associated with lytic cell death in enterocytes in worm-induced type 2 immunity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  57. SUN W, Ma X, Wang H, Du Y, et al
    MYO1F regulates antifungal immunity by regulating acetylation of microtubules.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  58. YANG WH, Westman JS, Heithoff DM, Sperandio M, et al
    Neu3 neuraminidase induction triggers intestinal inflammation and colitis in a model of recurrent human food-poisoning.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  59. CHEN KW, Demarco B, Ramos S, Heilig R, et al
    RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    June 2021
  60. ARAGAW WW, Lee BM, Yang X, Zimmerman MD, et al
    Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H2-dependent reduction.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  61. WU C, Chen YW, Scheible M, Chang C, et al
    Genetic and molecular determinants of polymicrobial interactions in Fusobacterium nucleatum.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  62. YAN Q, Zhang W, Lin M, Teymournejad O, et al
    Iron robbery by intracellular pathogen via bacterial effector-induced ferritinophagy.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  63. RAYNAUD C, Sheppard D, Berry JL, Gurung I, et al
    PilB from Streptococcus sanguinis is a bimodular type IV pilin with a direct role in adhesion.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  64. DI IULIO J, Bartha I, Spreafico R, Virgin HW, et al
    Transfer transcriptomic signatures for infectious diseases.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  65. DROTT MT, Rush TA, Satterlee TR, Giannone RJ, et al
    Microevolution in the pansecondary metabolome of Aspergillus flavus and its potential macroevolutionary implications for filamentous fungi.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  66. LABUDA JC, Pham OH, Depew CE, Fong KD, et al
    Circulating immunity protects the female reproductive tract from Chlamydia infection.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  67. LOFFREDO MR, Savini F, Bobone S, Casciaro B, et al
    Inoculum effect of antimicrobial peptides.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  68. MASISON J, Beezley J, Mei Y, Ribeiro H, et al
    A modular computational framework for medical digital twins.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  69. IM H, Hwang SH, Kim BS, Choi SH, et al
    Pathogenic potential assessment of the Shiga toxin-producing Escherichia coli by a source attribution-considered machine learning model.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  70. ZHANG W, Lin M, Yan Q, Budachetri K, et al
    An intracellular nanobody targeting T4SS effector inhibits Ehrlichia infection.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  71. LIU Q, Liu H, Shi L, Gan M, et al
    Local adaptation of Mycobacterium tuberculosis on the Tibetan Plateau.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  72. LI C, Zhou Z, Lumey LH
    Early-life exposure to the Chinese famine and tuberculosis risk: Unrecognized biases from different measures of famine intensity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    


  73. DONG W, Nie X, Zhu H, Liu Q, et al
    Mycobacterial fatty acid catabolism is repressed by FdmR to sustain lipogenesis and virulence.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  74. KOBAYASHI J, Kawakubo M, Fujii C, Arisaka N, et al
    Cholestenone functions as an antibiotic against Helicobacter pylori by inhibiting biosynthesis of the cell wall component CGL.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  75. SAMPERIO VENTAYOL P, Geiser P, Di Martino ML, Florbrant A, et al
    Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  76. LE VOYER T, Neehus AL, Yang R, Ogishi M, et al
    Inherited deficiency of stress granule ZNFX1 in patients with monocytosis and mycobacterial disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  77. AGGARWAL SD, Lloyd AJ, Yerneni SS, Narciso AR, et al
    A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  78. TEOH WP, Chen X, Laczkovich I, Alonzo F 3rd, et al
    Staphylococcus aureus adapts to the host nutritional landscape to overcome tissue-specific branched-chain fatty acid requirement.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  79. ANGST DC, Tepekule B, Sun L, Bogos B, et al
    Comparing treatment strategies to reduce antibiotic resistance in an in vitro epidemiological setting.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  80. RIMBARA E, Suzuki M, Matsui H, Nakamura M, et al
    Isolation and characterization of Helicobacter suis from human stomach.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  81. SINGH-BABAK SD, Babak T, Fraser HB, Johnson AD, et al
    Lineage-specific selection and the evolution of virulence in the Candida clade.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  82. FIEBIG A, Vrentas CE, Le T, Huebner M, et al
    Quantification of Brucella abortus population structure in a natural host.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  83. WHITWORTH LJ, Troll R, Pagan AJ, Roca FJ, et al
    Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  84. BERRYHILL BA, Huseby DL, McCall IC, Hughes D, et al
    Evaluating the potential efficacy and limitations of a phage for joint antibiotic and phage therapy of Staphylococcus aureus infections.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  85. WU J, Bao C, Reinhardt RL, Abraham SN, et al
    Local induction of bladder Th1 responses to combat urinary tract infections.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  86. CHIANG N, de la Rosa X, Libreros S, Pan H, et al
    Cysteinyl-specialized proresolving mediators link resolution of infectious inflammation and tissue regeneration via TRAF3 activation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  87. CHANG YL, Rossetti M, Gjertson DW, Rubbi L, et al
    Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  88. RAFFA N, Won TH, Sukowaty A, Candor K, et al
    Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  89. HUEMER M, Mairpady Shambat S, Bergada-Pijuan J, Soderholm S, et al
    Molecular reprogramming and phenotype switching in Staphylococcus aureus lead to high antibiotic persistence and affect therapy success.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  90. CRUZ AR, Boer MAD, Strasser J, Zwarthoff SA, et al
    Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    January 2021
  91. HANNA CC, Ashhurst AS, Quan D, Maxwell JWC, et al
    Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  92. WANG Y, He K, Sheng B, Lei X, et al
    The RNA helicase Dhx15 mediates Wnt-induced antimicrobial protein expression in Paneth cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  93. EZENWA VO, Budischak SA, Buss P, Seguel M, et al
    Natural resistance to worms exacerbates bovine tuberculosis severity independently of worm coinfection.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  94. HOU P, Jia P, Yang K, Li Z, et al
    An unconventional role of an ASB family protein in NF-kappaB activation and inflammatory response during microbial infection and colitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  95. SU H, Liu Q, Bian X, Wang S, et al
    Synthesis and delivery of Streptococcus pneumoniae capsular polysaccharides by recombinant attenuated Salmonella vaccines.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  96. SATERIALE A, Gullicksrud JA, Engiles JB, McLeod BI, et al
    The intestinal parasite Cryptosporidium is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  97. TOWELL AM, Feuillie C, Vitry P, Da Costa TM, et al
    Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  98. PRASAD JM, Negron O, Du X, Mullins ES, et al
    Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  99. OLDENKAMP R, Schultsz C, Mancini E, Cappuccio A, et al
    Filling the gaps in the global prevalence map of clinical antimicrobial resistance.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  100. INOMATA M, Xu S, Chandra P, Meydani SN, et al
    Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host aging.
    Proc Natl Acad Sci U S A. 2020;117:33561-33569.
    PubMed     Abstract available


  101. MAN K, Bowman C, Braverman KN, Escalante V, et al
    A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance.
    Proc Natl Acad Sci U S A. 2020;117:32029-32037.
    PubMed     Abstract available


  102. D'MELLO A, Riegler AN, Martinez E, Beno SM, et al
    An in vivo atlas of host-pathogen transcriptomes during Streptococcus pneumoniae colonization and disease.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2010428117.
    PubMed     Abstract available


  103. ZHONG W, Shi Z, Mahadevegowda SH, Liu B, et al
    Designer broad-spectrum polyimidazolium antibiotics.
    Proc Natl Acad Sci U S A. 2020;117:31376-31385.
    PubMed     Abstract available


  104. AUNINS TR, Erickson KE, Chatterjee A
    Transcriptome-based design of antisense inhibitors potentiates carbapenem efficacy in CRE Escherichia coli.
    Proc Natl Acad Sci U S A. 2020;117:30699-30709.
    PubMed     Abstract available


  105. LIM C, Berk JM, Blaise A, Bircher J, et al
    Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi.
    Proc Natl Acad Sci U S A. 2020;117:30380-30390.
    PubMed     Abstract available


    November 2020
  106. AKHADE AS, Atif SM, Lakshmi BS, Dikshit N, et al
    Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
    Proc Natl Acad Sci U S A. 2020;117:29811-29822.
    PubMed     Abstract available


  107. ZHANG H, Zoued A, Liu X, Sit B, et al
    Type I interferon remodels lysosome function and modifies intestinal epithelial defense.
    Proc Natl Acad Sci U S A. 2020;117:29862-29871.
    PubMed     Abstract available


  108. ZULAUF KE, Kirby JE
    Discovery of small-molecule inhibitors of multidrug-resistance plasmid maintenance using a high-throughput screening approach.
    Proc Natl Acad Sci U S A. 2020;117:29839-29850.
    PubMed     Abstract available


  109. HENRIQUES P, Dello Iacono L, Gimeno A, Biolchi A, et al
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