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Articles published in PLoS Biol

Retrieve available abstracts of 51 articles:
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Single Articles


    June 2026
  1. AGA ONL, Moyo SJ, Manyahi J, Kibwana U, et al
    Evolutionary inference reveals global natural histories and predicted pathways of antimicrobial resistance in Klebsiella pneumoniae.
    PLoS Biol. 2026;24:e3003848.
    PubMed     Abstract available


    May 2026
  2. RISTOW LC, Blackburn EE, Jezewski AJ, Lin X, et al
    Cryptococcus neoformans adapts to host CO2 concentrations via metabolic and stress-response remodeling.
    PLoS Biol. 2026;24:e3003561.
    PubMed     Abstract available


  3. TODD K, Schneider O, Lawrence JM, Aronoff JL, et al
    Environmental redox conditions and strain variation define phenazine-mediated antagonism in co-infecting bacteria.
    PLoS Biol. 2026;24:e3003809.
    PubMed     Abstract available


    April 2026
  4. DINSHAW KM, Lien KA, Knight M, Ouonkap SVY, et al
    High-throughput characterization of Mycobacterium tuberculosis gene function across diverse conditions.
    PLoS Biol. 2026;24:e3003529.
    PubMed     Abstract available


    March 2026
  5. HSIEH YP, O'Keefe IP, Wang Z, Sun W, et al
    Magnesium depletion by Candida albicans unleashes two unusual modes of colistin resistance in Pseudomonas aeruginosa with different fitness costs.
    PLoS Biol. 2026;24:e3003673.
    PubMed     Abstract available


  6. CERCKEL G, Dereinne D, Ledesma-Garcia L, Meuric V, et al
    Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci.
    PLoS Biol. 2026;24:e3003718.
    PubMed     Abstract available


  7. ALI N, Voorhies M, Rodriguez RA, Sil A, et al
    The Rpd3 histone deacetylase is a critical regulator of temperature-mediated morphogenesis and virulence in the human fungal pathogen Histoplasma.
    PLoS Biol. 2026;24:e3003341.
    PubMed     Abstract available


    February 2026
  8. ZHOU X, Hilk A, Solis NV, Scott N, et al
    Recurrent mutations in the stress regulator Cap1 reveal a trade-off between azole resistance and oxidative stress response in Candida albicans.
    PLoS Biol. 2026;24:e3003631.
    PubMed     Abstract available


  9. MASSOL F
    An ecological model of vaginal dysbiosis provides new research leads.
    PLoS Biol. 2026;24:e3003604.
    PubMed     Abstract available


  10. KAMIYA T, Sofonea MT, France M, Tessandier N, et al
    Resource landscape shapes the composition and stability of the human vaginal microbiota.
    PLoS Biol. 2026;24:e3003575.
    PubMed     Abstract available


  11. SON YE, Perez-Arques C, Heitman J
    Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in pathogenic Mucor fungi.
    PLoS Biol. 2026;24:e3003598.
    PubMed     Abstract available


  12. FENG C, Wang G, Wang Y, Gao X, et al
    Microglia sense fungal infections through capsular components from capillary-bound Cryptococcus neoformans via endothelial nucleotide signaling.
    PLoS Biol. 2026;24:e3003642.
    PubMed     Abstract available


  13. QUINN-BOHMANN N, Carr AV, Gibbons SM
    Metabolic modeling reveals determinants of prebiotic and probiotic treatment efficacy across multiple human intervention trials.
    PLoS Biol. 2026;24:e3003638.
    PubMed     Abstract available


    January 2026
  14. HEATER S, Voorhies M, Rodriguez RA, English BC, et al
    Rapid gain and loss of a chromosome drives key morphology and virulence phenotypes in the fungal pathogen Histoplasma.
    PLoS Biol. 2026;24:e3003224.
    PubMed     Abstract available


  15. GOWDY G, Prince A
    How do immunometabolites shape bacterial infections?
    PLoS Biol. 2026;24:e3003585.
    PubMed     Abstract available


  16. SANG Y, Ren J, Aballay A
    A gut-activated NHR-86-CYP pathway mediates the neuroprotective effects of Enterococcus faecium probiotics in a nematode model of amyotrophic lateral sclerosis.
    PLoS Biol. 2026;24:e3003627.
    PubMed     Abstract available


    December 2025
  17. VEZINA B, Cooper HB, Barlow CK, Rethoret-Pasty M, et al
    A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and capacity for intra-species co-operation.
    PLoS Biol. 2025;23:e3003559.
    PubMed     Abstract available


    October 2025
  18. FU C, Xiong EH, Kupczok L, Archambault LS, et al
    Expansion of the functional genomics GRACE library reveals genes relevant for temperature-dependent fitness in Candida albicans.
    PLoS Biol. 2025;23:e3003409.
    PubMed     Abstract available


    September 2025
  19. MEADE RK, Adefisayo OO, Gontijo MTP, Harris SJ, et al
    Cathepsin Z is a conserved susceptibility factor underlying tuberculosis severity.
    PLoS Biol. 2025;23:e3003377.
    PubMed     Abstract available


  20. POKHREL A, Chisholm L, Costas A, Pittorino M, et al
    Uropathogenic Escherichia coli proliferate as a coccoid morphotype inside human host cells.
    PLoS Biol. 2025;23:e3003366.
    PubMed     Abstract available


    August 2025
  21. KRISHNA A, Tonkin-Hill G, Morel-Journel T, Bentley S, et al
    Quantifying the effects of antibiotic resistance and within-host competition on strain fitness in Streptococcus pneumoniae.
    PLoS Biol. 2025;23:e3003300.
    PubMed     Abstract available


  22. BABU SAIT MR, Jachmann LH, Turkoz G, Milivojevic M, et al
    Genome-wide identification of modulators of Chlamydia trachomatis parasitophorous vacuole stability highlights an important role for sphingolipid supply.
    PLoS Biol. 2025;23:e3003297.
    PubMed     Abstract available


    July 2025
  23. RAVISHANKAR S, Tuohey SM, Ramos NO, Uchiyama S, et al
    Group B Streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model.
    PLoS Biol. 2025;23:e3003236.
    PubMed     Abstract available


  24. YEK KQ, Hodgson ER, Ang CS, Palmer CS, et al
    Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins.
    PLoS Biol. 2025;23:e3003261.
    PubMed     Abstract available


    May 2025
  25. SWISTAK L, Albert M, Valenzuela C, Gokerkucuk EB, et al
    The bacterial type three secretion system induces mechanoporation of vacuolar membranes.
    PLoS Biol. 2025;23:e3003135.
    PubMed     Abstract available


  26. BILLMYRE RB, Craig CJ, Lyon JW, Reichardt C, et al
    Landscape of essential growth and fluconazole-resistance genes in the human fungal pathogen Cryptococcus neoformans.
    PLoS Biol. 2025;23:e3003184.
    PubMed     Abstract available


    April 2025
  27. CHOW SH, Jeon Y, Deo P, Yeung ATY, et al
    Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid.
    PLoS Biol. 2025;23:e3003080.
    PubMed     Abstract available


  28. HU T, Zheng Q, Cao C, Li S, et al
    An agricultural triazole induces genomic instability and haploid cell formation in the human fungal pathogen Candida tropicalis.
    PLoS Biol. 2025;23:e3003062.
    PubMed     Abstract available


  29. OLANDER M, Rea Vazquez D, Meier K, Singh A, et al
    A multi-strategy antimicrobial discovery approach reveals new ways to treat Chlamydia.
    PLoS Biol. 2025;23:e3003123.
    PubMed     Abstract available


  30. HOMER CM, Voorhies M, Walcott K, Ochoa E, et al
    Transcriptomic atlas throughout Coccidioides development reveals key phase-enriched transcripts of this important fungal pathogen.
    PLoS Biol. 2025;23:e3003066.
    PubMed     Abstract available


    February 2025
  31. PONCIN K, McKeand SA, Lavender H, Kurzyp K, et al
    Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis.
    PLoS Biol. 2025;23:e3003001.
    PubMed     Abstract available


  32. SINGH DND, Roberts ARE, Wang X, Li G, et al
    Toll-1-dependent immune evasion induced by fungal infection leads to cell loss in the Drosophila brain.
    PLoS Biol. 2025;23:e3003020.
    PubMed     Abstract available


    January 2025
  33. WIELERT I, Kraus-Romer S, Volkmann TE, Craig L, et al
    Pilin antigenic variants impact gonococcal lifestyle and antibiotic tolerance by modulating interbacterial forces.
    PLoS Biol. 2025;23:e3003022.
    PubMed     Abstract available


    December 2024
  34. MALHOTRA N, Oh S, Finin P, Medrano J, et al
    Environmental fungi target thiol homeostasis to compete with Mycobacterium tuberculosis.
    PLoS Biol. 2024;22:e3002852.
    PubMed     Abstract available


    September 2024
  35. MAYFIELD JA, Raman S, Ramnarine AK, Mishra VK, et al
    Mycobacteria that cause tuberculosis have retained ancestrally acquired genes for the biosynthesis of chemically diverse terpene nucleosides.
    PLoS Biol. 2024;22:e3002813.
    PubMed     Abstract available


  36. MASS S, Cohen H, Podicheti R, Rusch DB, et al
    The coral pathogen Vibrio coralliilyticus uses a T6SS to secrete a group of novel anti-eukaryotic effectors that contribute to virulence.
    PLoS Biol. 2024;22:e3002734.
    PubMed     Abstract available


    August 2024
  37. KRISHNAN N, Priestman M, Uhia I, Charitakis N, et al
    A noninvasive BCG skin challenge model for assessing tuberculosis vaccine efficacy.
    PLoS Biol. 2024;22:e3002766.
    PubMed     Abstract available


  38. KRISHNAKANT KUSHWAHA S, Wu Y, Leonardo Avila H, Anand A, et al
    Comprehensive blueprint of Salmonella genomic plasticity identifies hotspots for pathogenicity genes.
    PLoS Biol. 2024;22:e3002746.
    PubMed     Abstract available


  39. MIKI T, Uemura T, Kinoshita M, Ami Y, et al
    Salmonella Typhimurium exploits host polyamines for assembly of the type 3 secretion machinery.
    PLoS Biol. 2024;22:e3002731.
    PubMed     Abstract available


  40. WOODWARD SE, Neufeld LMP, Pena-Diaz J, Feng W, et al
    Both pathogen and host dynamically adapt pH responses along the intestinal tract during enteric bacterial infection.
    PLoS Biol. 2024;22:e3002761.
    PubMed     Abstract available


  41. PEDERSEN BH, Simoes FB, Pogrebnyakov I, Welch M, et al
    Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
    PLoS Biol. 2024;22:e3002781.
    PubMed     Abstract available


    July 2024
  42. ANTUNES B, Zanchi C, Johnston PR, Maron B, et al
    The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures.
    PLoS Biol. 2024;22:e3002692.
    PubMed     Abstract available


  43. YAMAMOTO R, Miki H, Itani A, Takeshita N, et al
    Hyphae of the fungus Aspergillus nidulans demonstrate chemotropism to nutrients and pH.
    PLoS Biol. 2024;22:e3002726.
    PubMed     Abstract available


    June 2024
  44. RAI LS, Chauvel M, Sanchez H, van Wijlick L, et al
    Metabolic reprogramming during Candida albicans planktonic-biofilm transition is modulated by the transcription factors Zcf15 and Zcf26.
    PLoS Biol. 2024;22:e3002693.
    PubMed     Abstract available


  45. CHERRAK Y, Salazar MA, Yilmaz K, Kreuzer M, et al
    Commensal E. coli limits Salmonella gut invasion during inflammation by producing toxin-bound siderophores in a tonB-dependent manner.
    PLoS Biol. 2024;22:e3002616.
    PubMed     Abstract available


  46. COELHO MA, David-Palma M, Shea T, Bowers K, et al
    Comparative genomics of the closely related fungal genera Cryptococcus and Kwoniella reveals karyotype dynamics and suggests evolutionary mechanisms of pathogenesis.
    PLoS Biol. 2024;22:e3002682.
    PubMed     Abstract available


    May 2024
  47. BLAND DM, Long D, Rosenke R, Hinnebusch BJ, et al
    Yersinia pestis can infect the Pawlowsky glands of human body lice and be transmitted by louse bite.
    PLoS Biol. 2024;22:e3002625.
    PubMed     Abstract available


    April 2024
  48. MAURE A, Lawaree E, Fiorentino F, Pawlik A, et al
    A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection.
    PLoS Biol. 2024;22:e3002259.
    PubMed     Abstract available


  49. ZAMORA PF, Reidy TG, Armbruster CR, Sun M, et al
    Lytic bacteriophages induce the secretion of antiviral and proinflammatory cytokines from human respiratory epithelial cells.
    PLoS Biol. 2024;22:e3002566.
    PubMed     Abstract available


  50. ERNST C, Andreassen PR, Giger GH, Nguyen BD, et al
    Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution.
    PLoS Biol. 2024;22:e3002597.
    PubMed     Abstract available


    March 2024
  51. GROVER M, Gang SS, Troemel ER, Barkoulas M, et al
    Proteasome inhibition triggers tissue-specific immune responses against different pathogens in C. elegans.
    PLoS Biol. 2024;22:e3002543.
    PubMed     Abstract available


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