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Articles published in J Clin Invest

Retrieve available abstracts of 57 articles:
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    July 2021
  1. BRANDENBURG J, Marwitz S, Tazoll SC, Waldow F, et al
    WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis.
    J Clin Invest. 2021 Jul 13. pii: e141833. doi: 10.1172/JCI141833.
    PubMed     Abstract available

    June 2021
  2. REICHMANN MT, Tezera LB, Vallejo AF, Vukmirovic M, et al
    Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets.
    J Clin Invest. 2021 Jun 15. pii: e148136. doi: 10.1172/JCI148136.
    PubMed     Abstract available

  3. MIOW QH, Vallejo AF, Wang Y, Hong JM, et al
    Doxycycline host-directed therapy in human pulmonary tuberculosis.
    J Clin Invest. 2021 Jun 15. pii: e141895. doi: 10.1172/JCI141895.
    PubMed     Abstract available

    May 2021
  4. RIOU C, Du Bruyn E, Stek C, Daroowala R, et al
    Relationship of SARS-CoV-2-specific CD4 response to COVID-19 severity and impact of HIV-1 and Tuberculosis co-infection.
    J Clin Invest. 2021 May 4. pii: 149125. doi: 10.1172/JCI149125.
    PubMed     Abstract available

    April 2021
  5. OGONGO P, Tezera LB, Ardain A, Nhamoyebonde S, et al
    Tissue resident-like CD4+ T cells secreting IL-17 control Mycobacteria tuberculosis in the human lung.
    J Clin Invest. 2021 Apr 13. pii: 142014. doi: 10.1172/JCI142014.
    PubMed     Abstract available

    March 2021
  6. ORDONEZ AA, Tucker EW, Anderson CJ, Carter CL, et al
    Visualizing the dynamics of tuberculosis pathology using molecular imaging.
    J Clin Invest. 2021;131.
    PubMed     Abstract available

  7. PATRICK GJ, Liu H, Alphonse MP, Dikeman DA, et al
    Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease.
    J Clin Invest. 2021;131.
    PubMed     Abstract available

    February 2021
  8. BOOM WH, Schaible UE, Achkar JM
    The knowns and unknowns of latent Mycobacterium tuberculosis infection.
    J Clin Invest. 2021;131.
    PubMed     Abstract available

    January 2021
  9. DESHAYES DE CAMBRONNE R, Fouet A, Picart A, Bourrel AS, et al
    CC17 Group B Streptococcus exploits integrins for neonatal meningitis development.
    J Clin Invest. 2021 Jan 19. pii: 136737. doi: 10.1172/JCI136737.
    PubMed     Abstract available

    December 2020
  10. ZHAO M, Zhang F, Zarnowski R, Barns KJ, et al
    Turbinmicin inhibits Candida biofilm growth by disrupting fungal vesicle-mediated trafficking.
    J Clin Invest. 2020 Dec 29. pii: 145123. doi: 10.1172/JCI145123.
    PubMed     Abstract available

  11. WECKEL A, Guilbert T, Lambert C, Plainvert C, et al
    Streptococcuspyogenes infects human endometrium by limiting the innate immune response.
    J Clin Invest. 2020 Dec 15. pii: 130746. doi: 10.1172/JCI130746.
    PubMed     Abstract available

  12. BHATTACHARYA B, Xiao S, Chatterjee S, Urbanowski ME, et al
    The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas.
    J Clin Invest. 2020 Dec 10. pii: 130319. doi: 10.1172/JCI130319.
    PubMed     Abstract available

  13. GUO Y, Li L, Xu T, Guo X, et al
    HUWE1 mediates inflammasome activation and promotes host defense against bacterial infection.
    J Clin Invest. 2020;130:6301-6316.
    PubMed     Abstract available

    October 2020
  14. PRENTICE S, Dockrell HM
    Antituberculosis BCG vaccination: more reasons for varying innate and adaptive immune responses.
    J Clin Invest. 2020;130:5121-5123.
    PubMed     Abstract available

  15. TAKESHIMA H, Niwa T, Yamashita S, Takamura-Enya T, et al
    TET repression and increased DNMT activity synergistically induce aberrant DNA methylation.
    J Clin Invest. 2020;130:5370-5379.
    PubMed     Abstract available

    September 2020
  16. IGNATIUS EH, Cohen KA, Bishai WR
    Getting to the point in point-of-care diagnostics for tuberculosis.
    J Clin Invest. 2020 Sep 28. pii: 142497. doi: 10.1172/JCI142497.
    PubMed     Abstract available

  17. PIROFSKI LA, Casadevall A
    The state of latency in microbial pathogenesis.
    J Clin Invest. 2020;130:4525-4531.
    PubMed     Abstract available

  18. BRYAN AM, You JK, McQuiston T, Lazzarini C, et al
    FTY720 reactivates cryptococcal granulomas in mice through S1P receptor 3 on macrophages.
    J Clin Invest. 2020;130:4546-4560.
    PubMed     Abstract available

    August 2020
    Treatment of latent M. tuberculosis infection and use of antiretroviral therapy to prevent tuberculosis.
    J Clin Invest. 2020 Aug 24. pii: 137294. doi: 10.1172/JCI137294.
    PubMed     Abstract available

    July 2020
  20. BROGER T, Nicol M, Sigal G, Gotuzzo E, et al
    Diagnostic accuracy of three urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients.
    J Clin Invest. 2020 Jul 21. pii: 140461. doi: 10.1172/JCI140461.
    PubMed     Abstract available

  21. HAN T, Jing X, Bao J, Zhao L, et al
    H. pylori infection alters repair of DNA double-strand breaks via SNHG17.
    J Clin Invest. 2020;130:3901-3918.
    PubMed     Abstract available

  22. ALANIO A
    Dormancy in Cryptococcus neoformans: 60 years of accumulating evidence.
    J Clin Invest. 2020;130:3353-3360.
    PubMed     Abstract available

  23. DRAGOTAKES Q, Stouffer KM, Fu MS, Sella Y, et al
    Macrophages use a bet-hedging strategy for antimicrobial activity in phagolysosomal acidification.
    J Clin Invest. 2020;130:3805-3819.
    PubMed     Abstract available

    June 2020
  24. GANATRA SR, Bucsan AN, Alvarez X, Kumar S, et al
    Anti-retroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV co-infection model.
    J Clin Invest. 2020 Jun 16. pii: 136502. doi: 10.1172/JCI136502.
    PubMed     Abstract available

  25. SHIBATA T, Makino A, Ogata R, Nakamura S, et al
    Respiratory syncytial virus infection exacerbates pneumococcal pneumonia via Gas6/Axl-mediated macrophage polarization.
    J Clin Invest. 2020;130:3021-3037.
    PubMed     Abstract available

  26. KERNER G, Rosain J, Guerin A, Al-Khabaz A, et al
    Inherited human IFN-gamma deficiency underlies mycobacterial disease.
    J Clin Invest. 2020;130:3158-3171.
    PubMed     Abstract available

  27. KIM EY, Ner-Gaon H, Varon J, Cullen AM, et al
    Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-gamma in NK cells.
    J Clin Invest. 2020;130:3238-3252.
    PubMed     Abstract available

    May 2020
  28. DORHOI A, Kotze LA, Berzofsky JA, Sui Y, et al
    Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus.
    J Clin Invest. 2020 May 18. pii: 136288. doi: 10.1172/JCI136288.
    PubMed     Abstract available

  29. SAENZ JB, Mills JC
    Helicobacter pylori: preying on SIVA for survival in the stomach.
    J Clin Invest. 2020;130:2183-2185.
    PubMed     Abstract available

    Posttreatment Lyme disease syndromes: distinct pathogenesis caused by maladaptive host responses.
    J Clin Invest. 2020;130:2148-2151.

  31. CHEN YS, Chen IB, Pham G, Shao TY, et al
    IL-17-producing gammadelta T cells protect against Clostridium difficile infection.
    J Clin Invest. 2020;130:2377-2390.
    PubMed     Abstract available

    April 2020
  32. FOWLER VG JR, Das AF, Lipka-Diamond J, Schuch R, et al
    Exebacase for Staphylococcus aureus bloodstream infection and endocarditis.
    J Clin Invest. 2020 Apr 9. pii: 136577. doi: 10.1172/JCI136577.
    PubMed     Abstract available

  33. ORVAIN C, Lin YL, Jean-Louis F, Hocini H, et al
    Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa.
    J Clin Invest. 2020 Apr 2. pii: 131180. doi: 10.1172/JCI131180.
    PubMed     Abstract available

  34. ORTIZ-MUNOZ G, Yu MA, Lefrancais E, Mallavia B, et al
    Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation.
    J Clin Invest. 2020;130:2041-2053.
    PubMed     Abstract available

    March 2020
  35. SCOTT NR, Swanson RV, Al-Hammadi N, Domingo-Gonzalez R, et al
    S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis.
    J Clin Invest. 2020 Mar 5. pii: 130546. doi: 10.1172/JCI130546.
    PubMed     Abstract available

  36. DINARDO A, Rajapakshe K, Nishiguchi T, Mtetwa G, et al
    DNA hyper-methylation during Tuberculosis dampens host immune responsiveness.
    J Clin Invest. 2020 Mar 3. pii: 134622. doi: 10.1172/JCI134622.
    PubMed     Abstract available

  37. SATOH TK, Mellett M, Meier-Schiesser B, Fenini G, et al
    IL-36gamma drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes.
    J Clin Invest. 2020;130:1417-1430.
    PubMed     Abstract available

    January 2020
  38. CHEN T, Blanc C, Liu Y, Ishida E, et al
    Capsular glycan recognition provides antibody-mediated immunity against tuberculosis.
    J Clin Invest. 2020 Jan 14. pii: 128459. doi: 10.1172/JCI128459.
    PubMed     Abstract available

  39. FLAK MB, Koenis DS, Sobrino A, Smith J, et al
    GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections.
    J Clin Invest. 2020;130:359-373.
    PubMed     Abstract available

  40. MALERBA M, Louis S, Cuvellier S, Shambat SM, et al
    Epidermal hepcidin is required for neutrophil response to bacterial infection.
    J Clin Invest. 2020;130:329-334.
    PubMed     Abstract available

  41. LIN WC, Gowdy KM, Madenspacher JH, Zemans RL, et al
    Epithelial membrane protein 2 governs transepithelial migration of neutrophils into the airspace.
    J Clin Invest. 2020;130:157-170.
    PubMed     Abstract available

    December 2019
  42. LEE B, Olaniyi R, Kwiecinski J, Bubeck Wardenburg J, et al
    Staphylococcus aureus alpha-toxin suppresses antigen-specific T cell responses.
    J Clin Invest. 2019 Dec 24. pii: 130728. doi: 10.1172/JCI130728.
    PubMed     Abstract available

    November 2019
  43. OGONGO P, Steyn AJ, Karim F, Dullabh KJ, et al
    Differential skewing of donor-unrestricted and gammadelta T cell repertoires in tuberculosis-infected human lungs.
    J Clin Invest. 2019 Nov 25. pii: 130711. doi: 10.1172/JCI130711.
    PubMed     Abstract available

  44. KULICKE CA, Lewinsohn DA, Lewinsohn DM
    Clonal enrichments of Vdelta2- gammadelta T cells in Mycobacterium tuberculosis-infected human lungs.
    J Clin Invest. 2019 Nov 25. pii: 133119. doi: 10.1172/JCI133119.
    PubMed     Abstract available

    October 2019
  45. FATIMA S, Kamble SS, Dwivedi VP, Bhattacharya D, et al
    Mycobacterium tuberculosis Programs Mesenchymal Stem Cells to Establish Dormancy and Persistence.
    J Clin Invest. 2019 Oct 24. pii: 128043. doi: 10.1172/JCI128043.
    PubMed     Abstract available

    September 2019
  46. JORCH SK, Surewaard BG, Hossain M, Peiseler M, et al
    Peritoneal GATA6+ macrophages function as a portal for Staphylococcus aureus dissemination.
    J Clin Invest. 2019 Sep 23. pii: 127286. doi: 10.1172/JCI127286.
    PubMed     Abstract available

  47. BUCSAN AN, Chatterjee A, Singh DK, Foreman TW, et al
    Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection.
    J Clin Invest. 2019 Sep 3. pii: 125810. doi: 10.1172/JCI125810.
    PubMed     Abstract available

  48. KHADER SA, Divangahi M, Hanekom W, Hill PC, et al
    Targeting innate immunity for tuberculosis vaccination.
    J Clin Invest. 2019;129:3482-3491.
    PubMed     Abstract available

    April 2019
  49. COHEN TS, Takahashi V, Bonnell J, Tovchigrechko A, et al
    Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice.
    J Clin Invest. 2019;130.
    PubMed     Abstract available

    January 2019
  50. STONE NR, Rhodes J, Fisher MC, Mfinanga S, et al
    Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis.
    J Clin Invest. 2019 Jan 28. pii: 124516. doi: 10.1172/JCI124516.
    PubMed     Abstract available

  51. HILL HR
    Fitness genes of group A streptococci in necrotizing fasciitis and myositis.
    J Clin Invest. 2019 Jan 22. pii: 126482. doi: 10.1172/JCI126482.
    PubMed     Abstract available

  52. ZHU L, Olsen RJ, Beres SB, Eraso JM, et al
    Gene fitness landscape of group A streptococcus during necrotizing myositis.
    J Clin Invest. 2019 Jan 22. pii: 124994. doi: 10.1172/JCI124994.
    PubMed     Abstract available

    November 2018
    Why are diabetics prone to kidney infections?
    J Clin Invest. 2018 Nov 12. pii: 124922. doi: 10.1172/JCI124922.
    PubMed     Abstract available

    July 2018
  54. MYLES IA, Anderson ED, Earland NJ, Zarember KA, et al
    TNF overproduction impairs epithelial staphylococcal response in hyper IgE syndrome.
    J Clin Invest. 2018 Jul 23. pii: 121486. doi: 10.1172/JCI121486.
    PubMed     Abstract available

    April 2018
  55. VORNHAGEN J, Armistead B, Santana-Ufret V, Gendrin C, et al
    Group B streptococcus exploits vaginal epithelial exfoliation for ascending infection.
    J Clin Invest. 2018 Apr 9. pii: 97043. doi: 10.1172/JCI97043.
    PubMed     Abstract available

    February 2018
  56. HOOK JL, Islam MN, Parker D, Prince AS, et al
    Disruption of staphylococcal aggregation protects against lethal lung injury.
    J Clin Invest. 2018 Feb 12. pii: 95823. doi: 10.1172/JCI95823.
    PubMed     Abstract available

  57. DILLEN CA, Pinsker BL, Marusina AI, Merleev AA, et al
    Clonally expanded gammadelta T cells protect against Staphylococcus aureus skin reinfection.
    J Clin Invest. 2018 Feb 5. pii: 96481. doi: 10.1172/JCI96481.
    PubMed     Abstract available

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