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  Irritable Bowel Syndrome

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Articles published in Gut

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    August 2021
  1. SO D, Gibson PR, Muir JG, Yao CK, et al
    Dietary fibres and IBS: translating functional characteristics to clinical value in the era of personalised medicine.
    Gut. 2021 Aug 20. pii: gutjnl-2021-324891. doi: 10.1136/gutjnl-2021-324891.
    PubMed     Abstract available

  2. BLACK CJ, Staudacher HM, Ford AC
    Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis.
    Gut. 2021 Aug 10. pii: gutjnl-2021-325214. doi: 10.1136/gutjnl-2021-325214.
    PubMed     Abstract available

  3. GUNN D, Abbas Z, Harris HC, Major G, et al
    Psyllium reduces inulin-induced colonic gas production in IBS: MRI and in vitro fermentation studies.
    Gut. 2021 Aug 5. pii: gutjnl-2021-324784. doi: 10.1136/gutjnl-2021-324784.
    PubMed     Abstract available

    April 2021
  4. VASANT DH, Paine PA, Black CJ, Houghton LA, et al
    British Society of Gastroenterology guidelines on the management of irritable bowel syndrome.
    Gut. 2021 Apr 26. pii: gutjnl-2021-324598. doi: 10.1136/gutjnl-2021-324598.
    PubMed     Abstract available

  5. BOLTE LA, Vich Vila A, Imhann F, Collij V, et al
    Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome.
    Gut. 2021 Apr 2. pii: gutjnl-2020-322670. doi: 10.1136/gutjnl-2020-322670.
    PubMed     Abstract available

    February 2021
    FMT in IBS: a call for caution.
    Gut. 2021;70:431.

    December 2020
  7. SPILLER RC, Jalanka J
    Brachyspira and IBS with diarrhoea: a Helicobacter pylori moment?
    Gut. 2020 Dec 24. pii: gutjnl-2020-323370. doi: 10.1136/gutjnl-2020-323370.

    November 2020
  8. JABBAR KS, Dolan B, Eklund L, Wising C, et al
    Association between Brachyspira and irritable bowel syndrome with diarrhoea.
    Gut. 2020 Nov 11. pii: gutjnl-2020-321466. doi: 10.1136/gutjnl-2020-321466.
    PubMed     Abstract available

    October 2020
  9. MASSIER L, Chakaroun R, Kovacs P, Heiker JT, et al
    Blurring the picture in leaky gut research: how shortcomings of zonulin as a biomarker mislead the field of intestinal permeability.
    Gut. 2020 Oct 9. pii: gutjnl-2020-323026. doi: 10.1136/gutjnl-2020-323026.

  10. PERNA E, Aguilera-Lizarraga J, Florens MV, Jain P, et al
    Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.
    Gut. 2020 Oct 6. pii: gutjnl-2020-321530. doi: 10.1136/gutjnl-2020-321530.
    PubMed     Abstract available

    September 2020
  11. BLACK CJ, Craig O, Gracie DJ, Ford AC, et al
    Comparison of the Rome IV criteria with the Rome III criteria for the diagnosis of irritable bowel syndrome in secondary care.
    Gut. 2020 Sep 24. pii: gutjnl-2020-322519. doi: 10.1136/gutjnl-2020-322519.
    PubMed     Abstract available

    May 2020
  12. REJ A, Buckle RL, Shaw CC, Trott N, et al
    Is CBT the dominant non-drug IBS treatment? The rise of dietary therapies.
    Gut. 2020 May 19. pii: gutjnl-2020-321658. doi: 10.1136/gutjnl-2020-321658.

  13. POTTER MDE, Goodsall TM, Walker MM, Talley NJ, et al
    Dual histamine blockade for the treatment of adult functional dyspepsia: a single centre experience.
    Gut. 2020;69:966.

    April 2020
  14. BLACK CJ, Thakur ER, Houghton LA, Quigley EMM, et al
    Efficacy of psychological therapies for irritable bowel syndrome: systematic review and network meta-analysis.
    Gut. 2020 Apr 10. pii: gutjnl-2020-321191. doi: 10.1136/gutjnl-2020-321191.
    PubMed     Abstract available

    March 2020
  15. JEFFERY IB, O'Herlihy E, Shanahan F, O' Toole PW, et al
    Microbiome alterations in IBS.
    Gut. 2020 Mar 5. pii: gutjnl-2020-320919. doi: 10.1136/gutjnl-2020-320919.

    February 2020
  16. BARBARA G, Ianiro G
    Faecal microbial transplantation in IBS: ready for prime time?
    Gut. 2020 Feb 26. pii: gutjnl-2019-320411. doi: 10.1136/gutjnl-2019-320411.

  17. BARBARO MR, Cremon C, Morselli-Labate AM, Di Sabatino A, et al
    Serum zonulin and its diagnostic performance in non-coeliac gluten sensitivity.
    Gut. 2020 Feb 14. pii: gutjnl-2019-319281. doi: 10.1136/gutjnl-2019-319281.
    PubMed     Abstract available

    January 2020
  18. BLACK CJ, Burr NE, Camilleri M, Earnest DL, et al
    Efficacy of pharmacological therapies in patients with IBS with diarrhoea or mixed stool pattern: systematic review and network meta-analysis.
    Gut. 2020;69:74-82.
    PubMed     Abstract available

  19. EDOGAWA S, Edwinson AL, Peters SA, Chikkamenahalli LL, et al
    Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS.
    Gut. 2020;69:62-73.
    PubMed     Abstract available

    December 2019
  20. EL-SALHY M, Hatlebakk JG, Gilja OH, Brathen Kristoffersen A, et al
    Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study.
    Gut. 2019 Dec 18. pii: gutjnl-2019-319630. doi: 10.1136/gutjnl-2019-319630.
    PubMed     Abstract available

  21. LIU H, Han M, Li SC, Tan G, et al
    Resilience of human gut microbial communities for the long stay with multiple dietary shifts.
    Gut. 2019;68:2254-2255.

    November 2019
  22. ONG J, Swift C, Allwood I, Norman R, et al
    Chronic diarrhoea: the indications for lower GI endoscopy when functional bowel disease is suspected.
    Gut. 2019;68:2100.

    October 2019
  23. HUGERTH LW, Andreasson A, Talley NJ, Forsberg AM, et al
    No distinct microbiome signature of irritable bowel syndrome found in a Swedish random population.
    Gut. 2019 Oct 10. pii: gutjnl-2019-318717. doi: 10.1136/gutjnl-2019-318717.
    PubMed     Abstract available

    September 2019
  24. TALLEY NJ, Holtmann GJ, Jones M, Koloski NA, et al
    Zonulin in serum as a biomarker fails to identify the IBS, functional dyspepsia and non-coeliac wheat sensitivity.
    Gut. 2019 Sep 28. pii: gutjnl-2019-318664. doi: 10.1136/gutjnl-2019-318664.

  25. LACKNER JM, Jaccard J
    Cognitive-behavioural therapy for IBS comes home: mapping a route for efficacy and efficiency in the digital age.
    Gut. 2019;68:1541-1542.

  26. ENCK P
    Primum non nocere: is faecal microbiota transplantation doing harm to patients with IBS?
    Gut. 2019;68:1722-1723.

    August 2019
  27. MISSELWITZ B, Butter M, Verbeke K, Fox MR, et al
    Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management.
    Gut. 2019 Aug 19. pii: gutjnl-2019-318404. doi: 10.1136/gutjnl-2019-318404.
    PubMed     Abstract available

    July 2019
  28. HUSEIN DM, Naim HY
    Impaired cell surface expression and digestive function of sucrase-isomaltase gene variants are associated with reduced efficacy of low FODMAPs diet in patients with IBS-D.
    Gut. 2019 Jul 22. pii: gutjnl-2019-319411. doi: 10.1136/gutjnl-2019-319411.

    June 2019
  29. MAYER EA, Labus J, Aziz Q, Tracey I, et al
    Role of brain imaging in disorders of brain-gut interaction: a Rome Working Team Report.
    Gut. 2019 Jun 7. pii: gutjnl-2019-318308. doi: 10.1136/gutjnl-2019-318308.
    PubMed     Abstract available

  30. FROST F, Kacprowski T, Ruhlemann MC, Franke A, et al
    Functional abdominal pain and discomfort (IBS) is not associated with faecal microbiota composition in the general population.
    Gut. 2019;68:1131-1133.

    April 2019
  31. EVERITT HA, Landau S, O'Reilly G, Sibelli A, et al
    Assessing telephone-delivered cognitive-behavioural therapy (CBT) and web-delivered CBT versus treatment as usual in irritable bowel syndrome (ACTIB): a multicentre randomised trial.
    Gut. 2019 Apr 10. pii: gutjnl-2018-317805. doi: 10.1136/gutjnl-2018-317805.
    PubMed     Abstract available

    January 2019
  32. ZHENG T, Eswaran S, Photenhauer AL, Merchant JL, et al
    Reduced efficacy of low FODMAPs diet in patients with IBS-D carrying sucrase-isomaltase (SI) hypomorphic variants.
    Gut. 2019 Jan 18. pii: gutjnl-2018-318036. doi: 10.1136/gutjnl-2018-318036.

    September 2018
  33. FORD AC, Gibson PR
    Efficacy of glutamine in postinfection IBS.
    Gut. 2018 Sep 22. pii: gutjnl-2018-317438. doi: 10.1136/gutjnl-2018-317438.

    August 2018
  34. ZHOU Q, Verne ML, Fields JZ, Lefante JJ, et al
    Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.
    Gut. 2018 Aug 14. pii: gutjnl-2017-315136. doi: 10.1136/gutjnl-2017-315136.
    PubMed     Abstract available

    July 2018
  35. POTTER MDE, Walker MM, Keely S, Talley NJ, et al
    What's in a name? 'Non-coeliac gluten or wheat sensitivity': controversies and mechanisms related to wheat and gluten causing gastrointestinal symptoms or disease.
    Gut. 2018 Jul 30. pii: gutjnl-2018-316360. doi: 10.1136/gutjnl-2018-316360.

  36. HALKJAER SI, Christensen AH, Lo BZS, Browne PD, et al
    Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study.
    Gut. 2018 Jul 6. pii: gutjnl-2018-316434. doi: 10.1136/gutjnl-2018-316434.
    PubMed     Abstract available

    June 2018
  37. HOLTMANN GJ, Talley NJ
    Inconsistent symptom clusters for functional gastrointestinal disorders in Asia: is Rome burning?
    Gut. 2018 Jun 19. pii: gutjnl-2017-314775. doi: 10.1136/gutjnl-2017-314775.

    March 2018
  38. WALDMAN SA, Camilleri M
    Guanylate cyclase-C as a therapeutic target in gastrointestinal disorders.
    Gut. 2018 Mar 21. pii: gutjnl-2018-316029. doi: 10.1136/gutjnl-2018-316029.
    PubMed     Abstract available

    January 2018
  39. THINGHOLM L, Ruhlemann M, Wang J, Hubenthal M, et al
    Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition.
    Gut. 2018 Jan 13. pii: gutjnl-2017-315841. doi: 10.1136/gutjnl-2017-315841.

    August 2017
  40. TACK J, Corsetti M, Camilleri M, Quigley EM, et al
    Plausibility criteria for putative pathophysiological mechanisms in functional gastrointestinal disorders: a consensus of experts.
    Gut. 2017 Aug 16. pii: gutjnl-2016-312230. doi: 10.1136/gutjnl-2016-312230.
    PubMed     Abstract available

    June 2017
  41. MAVRANGELOS C, Campaniello MA, Andrews JM, Bampton PA, et al
    Longitudinal analysis indicates symptom severity influences immune profile in irritable bowel syndrome.
    Gut. 2017 Jun 10. pii: gutjnl-2017-314308. doi: 10.1136/gutjnl-2017-314308.

  42. DONNACHIE E, Schneider A, Mehring M, Enck P, et al
    Incidence of irritable bowel syndrome and chronic fatigue following GI infection: a population-level study using routinely collected claims data.
    Gut. 2017 Jun 10. pii: gutjnl-2017-313713. doi: 10.1136/gutjnl-2017-313713.
    PubMed     Abstract available

  43. STAUDACHER HM, Whelan K
    The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in IBS.
    Gut. 2017 Jun 7. pii: gutjnl-2017-313750. doi: 10.1136/gutjnl-2017-313750.
    PubMed     Abstract available

    April 2017
  44. BENNET SMP, Bohn L, Storsrud S, Liljebo T, et al
    Multivariate modelling of faecal bacterial profiles of patients with IBS predicts responsiveness to a diet low in FODMAPs.
    Gut. 2017 Apr 17. pii: gutjnl-2016-313128. doi: 10.1136/gutjnl-2016-313128.
    PubMed     Abstract available

    March 2017
    Identification of an epithelial member of the protease family, supporting the potential diagnostic and therapeutic role of serine proteases in IBS.
    Gut. 2017 Mar 10. pii: gutjnl-2016-313664. doi: 10.1136/gutjnl-2016-313664.

  46. AN S, Zong G, Wang Z, Shi J, et al
    Activation of protease-activated receptor 4 of mast cells could downregulate proinflammatory cytokines in irritable bowel syndrome.
    Gut. 2017 Mar 8. pii: gutjnl-2016-313504. doi: 10.1136/gutjnl-2016-313504.

    February 2017
  47. CAMILLERI M, Boeckxstaens G
    Dietary and pharmacological treatment of abdominal pain in IBS.
    Gut. 2017 Feb 23. pii: gutjnl-2016-313425. doi: 10.1136/gutjnl-2016-313425.
    PubMed     Abstract available

    Novel insight in diarrhoea-predominant IBS: miRNAs modulate barrier function.
    Gut. 2017 Feb 9. pii: gutjnl-2016-313525. doi: 10.1136/gutjnl-2016-313525.

    January 2017
  49. SIMREN M, Tornblom H, Palsson OS, van Tilburg MA, et al
    Visceral hypersensitivity is associated with GI symptom severity in functional GI disorders: consistent findings from five different patient cohorts.
    Gut. 2017 Jan 19. pii: gutjnl-2016-312361. doi: 10.1136/gutjnl-2016-312361.
    PubMed     Abstract available

  50. ROLLAND-FOURCADE C, Denadai-Souza A, Cirillo C, Lopez C, et al
    Epithelial expression and function of trypsin-3 in irritable bowel syndrome.
    Gut. 2017 Jan 17. pii: gutjnl-2016-312094. doi: 10.1136/gutjnl-2016-312094.
    PubMed     Abstract available

  51. MARTINEZ C, Rodino-Janeiro BK, Lobo B, Stanifer ML, et al
    miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea.
    Gut. 2017 Jan 12. pii: gutjnl-2016-311477. doi: 10.1136/gutjnl-2016-311477.
    PubMed     Abstract available

    December 2016
  52. HENSTROM M, Hadizadeh F, Beyder A, Bonfiglio F, et al
    TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M.
    Gut. 2016 Dec 14. pii: gutjnl-2016-313346. doi: 10.1136/gutjnl-2016-313346.

    November 2016
  53. HENSTROM M, Diekmann L, Bonfiglio F, Hadizadeh F, et al
    Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome.
    Gut. 2016 Nov 21. pii: gutjnl-2016-312456. doi: 10.1136/gutjnl-2016-312456.
    PubMed     Abstract available

    August 2016
  54. HOLVOET T, Joossens M, Wang J, Boelens J, et al
    Assessment of faecal microbial transfer in irritable bowel syndrome with severe bloating.
    Gut. 2016 Aug 10. pii: gutjnl-2016-312513. doi: 10.1136/gutjnl-2016-312513.

    July 2016
  55. GOODSALL TM, Talley NJ, Rassam L, Wood NK, et al
    Unique pathology of colonic spirochaetosis characterised by mucosal eosinophilia is linked to diarrhoea and IBS.
    Gut. 2016 Jul 29. pii: gutjnl-2016-312405. doi: 10.1136/gutjnl-2016-312405.

    April 2016
  56. TACK J, Schumacher K, Tonini G, Scartoni S, et al
    The neurokinin-2 receptor antagonist ibodutant improves overall symptoms, abdominal pain and stool pattern in female patients in a phase II study of diarrhoea-predominant IBS.
    Gut. 2016 Apr 15. pii: gutjnl-2015-310683. doi: 10.1136/gutjnl-2015-310683.
    PubMed     Abstract available

    March 2016
  57. MCINTOSH K, Reed DE, Schneider T, Dang F, et al
    FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial.
    Gut. 2016 Mar 14. pii: gutjnl-2015-311339. doi: 10.1136/gutjnl-2015-311339.
    PubMed     Abstract available

    February 2016
  58. CASTRO J, Harrington AM, Garcia-Caraballo S, Maddern J, et al
    alpha-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors.
    Gut. 2016 Feb 17. pii: gutjnl-2015-310971. doi: 10.1136/gutjnl-2015-310971.
    PubMed     Abstract available

    January 2016
  59. SPERBER AD, Dumitrascu D, Fukudo S, Gerson C, et al
    The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review.
    Gut. 2016 Jan 27. pii: gutjnl-2015-311240. doi: 10.1136/gutjnl-2015-311240.
    PubMed     Abstract available

  60. WILDENBERG ME, van den Brink GR
    House dust mite: a new player in intestinal inflammation?
    Gut. 2016 Jan 13. pii: gutjnl-2015-311042. doi: 10.1136/gutjnl-2015-311042.

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