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  Valvular Heart Disease

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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 12 articles:
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Single Articles


    September 2022
  1. THE E, de Graaf DM, Zhai Y, Yao Q, et al
    Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3.
    Proc Natl Acad Sci U S A. 2022;119:e2202577119.
    PubMed     Abstract available


    July 2022
  2. AXELSSON RAJA A, Wakimoto H, DeLaughter DM, Reichart D, et al
    Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
    Proc Natl Acad Sci U S A. 2022;119:e2204174119.
    PubMed     Abstract available


    March 2022
  3. YANG ZF, Panwar P, McFarlane CR, Tuinte WE, et al
    Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
    Proc Natl Acad Sci U S A. 2022;119:e2120416119.
    PubMed     Abstract available


    February 2022
  4. ROGERS JD, Aguado BA, Watts KM, Anseth KS, et al
    Network modeling predicts personalized gene expression and drug responses in valve myofibroblasts cultured with patient sera.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  5. YUAN CC, Kazmierczak K, Liang J, Ma W, et al
    Molecular basis of force-pCa relation in MYL2 cardiomyopathy mice: Role of the super-relaxed state of myosin.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  6. ZAKHARCHENKO A, Xue Y, Keeney S, Rock CA, et al
    Poly-2-methyl-2-oxazoline-modified bioprosthetic heart valve leaflets have enhanced biocompatibility and resist structural degeneration.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    June 2021
  7. VANDER ROEST AS, Liu C, Morck MM, Kooiker KB, et al
    Hypertrophic cardiomyopathy beta-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  8. REPETTI GG, Kim Y, Pereira AC, Ingles J, et al
    Discordant clinical features of identical hypertrophic cardiomyopathy twins.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    October 2020
  9. SEGALES J, Puig M, Rodon J, Avila-Nieto C, et al
    Detection of SARS-CoV-2 in a cat owned by a COVID-19-affected patient in Spain.
    Proc Natl Acad Sci U S A. 2020;117:24790-24793.
    PubMed     Abstract available


  10. TUCHOLSKI T, Cai W, Gregorich ZR, Bayne EF, et al
    Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics.
    Proc Natl Acad Sci U S A. 2020;117:24691-24700.
    PubMed     Abstract available


    September 2020
  11. VIOLA HM, Shah AA, Johnstone VPA, Cserne Szappanos H, et al
    Characterization and validation of a preventative therapy for hypertrophic cardiomyopathy in a murine model of the disease.
    Proc Natl Acad Sci U S A. 2020;117:23113-23124.
    PubMed     Abstract available


    August 2020
  12. JOHNSON EL, Wu MCH, Xu F, Wiese NM, et al
    Thinner biological tissues induce leaflet flutter in aortic heart valve replacements.
    Proc Natl Acad Sci U S A. 2020;117:19007-19016.
    PubMed     Abstract available


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