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Herpes simplex Infection

Free Subscription Articles published in PLoS Pathog Retrieve available abstracts of 30 articles: HTML format

Single Articles

October 2026
1. FRIETZE S, Lunn C, Oldham D, Boyd JR, et al
   Intranasal HSV?1 infection drives region?specific interferon?dominant microglial remodeling.
   PLoS Pathog. 2026;22:e1014684.
   PubMed     Abstract available
   
   
   September 2026
2. ZIMENKO A, Hayman I, Fong Y, Monroe LD, et al
   Epithelial interferon-gamma responsiveness shapes chemokine induction and clinical outcomes in herpes simplex virus infection.
   PLoS Pathog. 2026;22:e1014612.
   PubMed     Abstract available
   
   
   
3. BIRKENHEUER CH, Edwards TG, Bloom DC, Baines JD, et al
   Analysis of host and viral nascent and steady-state RNA levels in a human neuronal model of herpes simplex virus 1 infection.
   PLoS Pathog. 2026;22:e1014603.
   PubMed     Abstract available
   
   
   
4. ARYA D, Tormanen K, Oh JJ, Wang S, et al
   Complete disruption of gD binding to HVEM alters virus replication and host receptor homeostasis.
   PLoS Pathog. 2026;22:e1014566.
   PubMed     Abstract available
   
   
   
5. JAGGI U, Wang S, Ghiasi H
   Epigenetic profiling reveals M1 macrophages as the primary drivers of trained immunity in HSV-1 latently infected mice.
   PLoS Pathog. 2026;22:e1014598.
   PubMed     Abstract available
   
   
   July 2026
6. KONIGHOFER E, Gustafsson C, Gudmundsdotter L, Mirgorodskaya E, et al
   Glycoprotein G enables HSV-2 neuroinvasion and provides protection as a glycosylated vaccine antigen.
   PLoS Pathog. 2026;22:e1014339.
   PubMed     Abstract available
   
   
   
7. ZHAO Y, Probert S, Birkel J, Liu X, et al
   Independent proviral and antiviral host factors recognize the same capsid protein in divergent human herpesviruses.
   PLoS Pathog. 2026;22:e1014376.
   PubMed     Abstract available
   
   
   June 2026
8. TIAN X, Wang X, Wang S, Zhong Y, et al
   SUMOylation and ubiquitination reciprocally regulate SMCHD1 antiviral activity against herpes simplex virus 1.
   PLoS Pathog. 2026;22:e1014371.
   PubMed     Abstract available
   
   
   
9. JAKI L, Full F, Gieraths U, Falcone V, et al
   Low frequency variants can predetermine antiviral drug resistance development in herpes simplex virus type 1.
   PLoS Pathog. 2026;22:e1014296.
   PubMed     Abstract available
   
   
   
10. HOOK LM, Cairns TM, Awasthi S, Egan KP, et al
    HSV-2 gC2 mRNA immunization in mice protects by producing antibodies that bind immune evasion epitopes.
    PLoS Pathog. 2026;22:e1014337.
    PubMed     Abstract available
    
    
    May 2026
11. ARYA D, Jaggi U, Oh JJ, Wang S, et al
    Partial or complete blocking of gD binding to HVEM affects primary and latent HSV-1 infection as well as eye disease in HSV-1 infected mice.
    PLoS Pathog. 2026;22:e1014258.
    PubMed     Abstract available
    
    
    January 2026
12. TERVONEN A, Ruokolainen V, Leclerc S, Tieu K, et al
    Nucleus softens during herpesvirus infection.
    PLoS Pathog. 2026;22:e1013873.
    PubMed     Abstract available
    
    
    November 2025
13. JAGGI U, Hirose S, Wang S, Ghiasi H, et al
    Divergent roles of macrophage subsets, FoxP3, and IL-17A in HSV-1-induced CNS pathology.
    PLoS Pathog. 2025;21:e1013696.
    PubMed     Abstract available
    
    
    August 2025
14. ROBERTS APE, Orr A, Iliev V, Orr L, et al
    Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription.
    PLoS Pathog. 2025;21:e1012501.
    PubMed     Abstract available
    
    
    May 2025
15. ARSHAD S, Rana H, Truong NR, Pattamatta U, et al
    Herpes simplex virus type-1 infection and spread in a novel porcine corneal explant model is restricted to the epithelium.
    PLoS Pathog. 2025;21:e1013162.
    PubMed     Abstract available
    
    
    
16. ALBANO C, Trifiro L, Hewelt-Belka W, Cairns DM, et al
    The impact of fatty acid synthase on HSV-1 infection dynamics.
    PLoS Pathog. 2025;21:e1013068.
    PubMed     Abstract available
    
    
    April 2025
17. PARCHURE A, Cesarec M, Braut A, Kolman R, et al
    ADAR1 p150 prevents HSV-1 from triggering PKR/eIF2alpha-mediated translational arrest and is required for efficient viral replication.
    PLoS Pathog. 2025;21:e1012452.
    PubMed     Abstract available
    
    
    February 2025
18. DUTTON AJ, Turnbaugh EM, Patel CD, Garland CR, et al
    Asymptomatic neonatal herpes simplex virus infection in mice leads to persistent CNS infection and long-term cognitive impairment.
    PLoS Pathog. 2025;21:e1012935.
    PubMed     Abstract available
    
    
    October 2024
19. WANG S, Jaggi U, Katsumata M, Ghiasi H, et al
    The importance of IFNalpha2A (Roferon-A) in HSV-1 latency and T cell exhaustion in ocularly infected mice.
    PLoS Pathog. 2024;20:e1012612.
    PubMed     Abstract available
    
    
    
20. SINGH P, Zhu L, Shipley MA, Ye ZA, et al
    The HSV-1 encoded CCCTC-binding factor, CTRL2, impacts the nature of viral chromatin during HSV-1 lytic infection.
    PLoS Pathog. 2024;20:e1012621.
    PubMed     Abstract available
    
    
    September 2024
21. WANG K, Jordan T, Dowdell K, Herbert R, et al
    A nonhuman primate model for genital herpes simplex virus 2 infection that results in vaginal vesicular lesions, virus shedding, and seroconversion.
    PLoS Pathog. 2024;20:e1012477.
    PubMed     Abstract available
    
    
    June 2024
22. RANA H, Truong NR, Johnson B, Baharlou H, et al
    Herpes simplex virus spreads rapidly in human foreskin, partly driven by chemokine-induced redistribution of Nectin-1 on keratinocytes.
    PLoS Pathog. 2024;20:e1012267.
    PubMed     Abstract available
    
    
    
23. YANG C, Wang CY, Long QY, Cao Z, et al
    The roles of nuclear orphan receptor NR2F6 in anti-viral innate immunity.
    PLoS Pathog. 2024;20:e1012271.
    PubMed     Abstract available
    
    
    April 2024
24. LECLERC S, Gupta A, Ruokolainen V, Chen JH, et al
    Progression of herpesvirus infection remodels mitochondrial organization and metabolism.
    PLoS Pathog. 2024;20:e1011829.
    PubMed     Abstract available
    
    
    December 2023
25. THOMAS ECM, Finnen RL, Mewburn JD, Archer SL, et al
    The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes.
    PLoS Pathog. 2023;19:e1011832.
    PubMed     Abstract available
    
    
    
26. PASQUERO S, Gugliesi F, Biolatti M, Dell'Oste V, et al
    Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors.
    PLoS Pathog. 2023;19:e1011849.
    PubMed     Abstract available
    
    
    July 2023
27. PACKARD JE, Williams MR, Fromuth DP, Dembowski JA, et al
    Proliferating cell nuclear antigen inhibitors block distinct stages of herpes simplex virus infection.
    PLoS Pathog. 2023;19:e1011539.
    PubMed     Abstract available
    
    
    
28. FU Y, Zhan X, You X, Nie D, et al
    USP12 promotes antiviral responses by deubiquitinating and stabilizing IFI16.
    PLoS Pathog. 2023;19:e1011480.
    PubMed     Abstract available
    
    
    
29. XUE Q, Zhu Z, Xue Z, Yang F, et al
    NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3.
    PLoS Pathog. 2023;19:e1011511.
    PubMed     Abstract available
    
    
    June 2023
30. PHEASANT K, Perry D, Wise EL, Cheng V, et al
    Dysregulated metabolism of the late herpes simplex virus 1 transcriptome through the vhs-VP22 axis uncouples virus cytopathic effect and virus production.
    PLoS Pathog. 2023;19:e1010966.
    PubMed     Abstract available
    
    

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