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  Head and Neck Cancer

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08.09.2025

2 BMC Cancer
3 Br J Cancer
1 Cancer Res
1 Clin Cancer Res
4 Clin Nucl Med
1 Dis Esophagus
2 Head Neck
1 Hum Pathol
2 J Clin Oncol
2 J Oral Maxillofac Surg
2 Laryngoscope
9 Oral Oncol
1 Otolaryngol Head Neck Surg
1 PLoS Genet
3 PLoS One
2 Radiother Oncol
2 Thyroid


  Retrieve available abstracts of this week’s articles:
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Single Articles


    BMC Cancer

  1. YAO W, Dong S, Xu P, Zhong Z, et al
    A subgroup analysis of locally advanced nasopharyngeal carcinoma patients with small lymph nodes and large nodes using adaptive radiotherapy.
    BMC Cancer. 2025;25:1414.
    PubMed         Abstract available

  2. MALTSEVA M, Klasen C, Wuerdemann N, Hannich M, et al
    Detection and natural history of HPV infection of oral cavity and tonsils - a systematic literature review.
    BMC Cancer. 2025;25:1405.
    PubMed         Abstract available


    Br J Cancer

  3. WALKER RC, Breininger SP, Sharpe BP, Harrington J, et al
    Cancer-associated fibroblasts are associated with neo-adjuvant treatment response in oesophageal adenocarcinoma.
    Br J Cancer. 2025;133:633-647.
    PubMed         Abstract available

  4. SPENDER LC, Watt DM, Baxter MA, Shuttleworth MK, et al
    AKT/mTOR as a targetable hub to overcome multimodal resistance to EGFR inhibitors in oesophageal squamous cell carcinoma.
    Br J Cancer. 2025;133:709-722.
    PubMed         Abstract available

  5. WU KP, Luo XQ, Li QQ, Yang HC, et al
    Efficacy and safety of induction immunotherapy plus chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a meta-analysis.
    Br J Cancer. 2025 Sep 5. doi: 10.1038/s41416-025-03169.
    PubMed         Abstract available


    Cancer Res

  6. OLEINIK NV, Atilgan FC, Kassir MF, Lee HG, et al
    Ceramide-Induced Metabolic Stress Depletes Fumarate and Drives Mitophagy to Mediate Tumor Suppression.
    Cancer Res. 2025;85:3313-3334.
    PubMed         Abstract available


    Clin Cancer Res

  7. HARRISON C, Blake AK, Su Y, Tang L, et al
    Contribution of Germline Predisposition to Pediatric Thyroid Cancer.
    Clin Cancer Res. 2025 Jun 27. doi: 10.1158/1078-0432.CCR-25-0631.
    PubMed         Abstract available


    Clin Nucl Med

  8. BRUMENT M, Zanetta S, Drouet C
    18F-Fluorocholine PET/CT for the Staging and Follow-up of a Patient Suffering From Metastatic Parathyroid Carcinoma.
    Clin Nucl Med. 2025;50:e617-e620.
    PubMed         Abstract available

  9. BILGIN C, Belge Bilgin G, Dundar B, Kapplinger JD, et al
    I-131 Uptake in a Benign Diaphragmatic Mesothelial Cyst Mimicking Thyroid Cancer Metastasis on Post-therapy SPECT/CT.
    Clin Nucl Med. 2025 Jul 1. doi: 10.1097/RLU.0000000000005923.
    PubMed         Abstract available

  10. LIU J, Liao X, Pang Y, Lin Q, et al
    Squamous Cell Carcinoma of the Tonsil Unmasked by 68Ga-FAPI-46 PET/CT.
    Clin Nucl Med. 2025 Mar 28. doi: 10.1097/RLU.0000000000005866.
    PubMed         Abstract available

  11. PERRONE E, Ghai K, Eismant A, Baum RP, et al
    TANDEM Peptide Receptor Radionuclide Therapy Using [ 225 Ac]Ac-/[ 177 Lu]Lu-DOTA-LM3 in a Patient With Parotid Gland Metastasis From Pancreatic Neuroendocrine Neoplasm.
    Clin Nucl Med. 2025;50:e605-e607.
    PubMed         Abstract available


    Dis Esophagus


  12. Correction to: The prevalence, nature and severity of oropharyngeal dysphagia in the acute post-operative phase following curative resection for esophageal cancer.
    Dis Esophagus. 2025;38:doaf074.
    PubMed        


    Head Neck

  13. BEN KRIDIS W, Khanfir A
    Efficacy and Safety of Adjuvant Capecitabine in Locoregionally Advanced Nasopharyngeal Carcinoma: A Meta-Analysis of Phase III Randomized Trials With Subgroup Analysis by Neoadjuvant Chemotherapy.
    Head Neck. 2025 Sep 3. doi: 10.1002/hed.70034.
    PubMed         Abstract available

  14. THAI AA, Young RJ, Bressel M, Ma BBY, et al
    Examining CD103(+) Tissue-Resident Memory T Cells in Nasopharyngeal Carcinoma.
    Head Neck. 2025 Sep 3. doi: 10.1002/hed.70026.
    PubMed         Abstract available


    Hum Pathol

  15. JIN J, Sun M, Yang X, Ding Z, et al
    Incidence of MSI-H esophageal carcinoma and related identification of genomic alterations: A multi-center real-world study.
    Hum Pathol. 2025;163:105878.
    PubMed         Abstract available


    J Clin Oncol

  16. DOUGAN M, Dougan SK
    Second Mitochondrial Activator of Caspases Mimetics Accelerate Progression of Locally Advanced Head and Neck Cancer.
    J Clin Oncol. 2025 Sep 3:JCO2501024. doi: 10.1200/JCO-25-01024.
    PubMed        

  17. BOURHIS J, Licitra LF, Burtness B, Psyrri A, et al
    Xevinapant or Placebo Plus Platinum-Based Chemoradiotherapy in Unresected Locally Advanced Squamous Cell Carcinoma of the Head and Neck (TrilynX): A Randomized, Phase III Study.
    J Clin Oncol. 2025 Sep 3:JCO2500272. doi: 10.1200/JCO-25-00272.
    PubMed         Abstract available


    J Oral Maxillofac Surg

  18. SENTHIL R
    Bevacizumab-Conjugated Curcumin Nanoparticles Promote Cytotoxicity and Apoptosis in Human Malignant Oral Keratinocytes In Vitro.
    J Oral Maxillofac Surg. 2025;83:1170-1178.
    PubMed         Abstract available

  19. MOHAMED AK, Arce K, Nathan JM, Vierkant RA, et al
    Patient-Specific Titanium Implants Reduce Hardware-Related Complications Compared to Stock Reconstruction Plates for Virtually Guided Fibular Free Flaps in Head and Neck Reconstruction.
    J Oral Maxillofac Surg. 2025;83:1157-1169.
    PubMed         Abstract available


    Laryngoscope

  20. MEGWALU UC, Ma Y, Divi V, Tian L, et al
    Mediators of Racial Disparities in Head and Neck Cancer Survival.
    Laryngoscope. 2025 Sep 5. doi: 10.1002/lary.70107.
    PubMed         Abstract available

  21. GULATI A, Patel N, Kidane J, Perrin CE, et al
    Prevalence of Long-Term Dysphagia in Head and Neck Cancer Survivors Not Receiving Dysphagia Treatment.
    Laryngoscope. 2025 Sep 3. doi: 10.1002/lary.70085.
    PubMed         Abstract available


    Oral Oncol

  22. KANA L, Chamma B, Robinette N, Cramer JD, et al
    Pre-treatment PET/CT for head and neck squamous cell carcinoma: secondary analysis of a clinical trial.
    Oral Oncol. 2025;169:107633.
    PubMed         Abstract available

  23. DAI Y, Li W
    Comment on "Randomized controlled trial of semi-individualized 3D-printed tissue retraction devices vs. standard shielding splints in head and neck cancer treated with intensity-modulated and particle radiotherapy (GUARD)" by Schroter et al.
    Oral Oncol. 2025;169:107640.
    PubMed        

  24. ANSARI E, Carrillo Minulina N, van Es RJJ, Dieleman FJ, et al
    Low skeletal muscle mass and not systemic inflammation is associated with complications after free forearm flap reconstruction in oral cancer patients.
    Oral Oncol. 2025;169:107628.
    PubMed         Abstract available

  25. BARRETT TF, Apicelli AJ, Ramadan S, Pipkorn P, et al
    Management of HPV+ head and neck squamous cell carcinoma with unknown primary in the era of treatment de-escalation.
    Oral Oncol. 2025;169:107631.
    PubMed         Abstract available

  26. BHAGIA P, Mukherjee A, Agarwal T, Giri S, et al
    Stroke risk after head and neck cancer diagnosis and treatment in a Real-World clinical cohort: Running title: Treatment in a Real-World clinical cohort.
    Oral Oncol. 2025;169:107599.
    PubMed         Abstract available

  27. KLEEBAYOON A, Wiwanitkit V
    Semi-individualized 3D-printed tissue retraction devices vs. standard shielding splints in head and neck cancer treated with intensity-modulated and particle radiotherapy (GUARD): correspondence.
    Oral Oncol. 2025;169:107645.
    PubMed        

  28. DUNN LA, Ho AL, Michel LS, Wong W, et al
    A phase 1/1b study of lenvatinib and cetuximab in patients with recurrent/metastatic head and neck squamous cell carcinoma.
    Oral Oncol. 2025;169:107524.
    PubMed         Abstract available

  29. BATOOL S, Hansen EE, Sethi RKV, Rettig EM, et al
    Financial instability, insurance, and transportation influence timely head and neck cancer care in the United States: Patient and healthcare worker perspectives.
    Oral Oncol. 2025;169:107607.
    PubMed         Abstract available

  30. PENG X, Xie Y, Liu Y
    Comment on "Prediction of clinical outcomes of immune checkpoint inhibitors in advanced head and neck cancer directly from histopathology slides using inferred transcriptomics".
    Oral Oncol. 2025;169:107644.
    PubMed        


    Otolaryngol Head Neck Surg

  31. WONG RSH, Sri Ram TM, Xia Y, Heng EH, et al
    Lobectomy Versus Total Thyroidectomy Across 2015 American Thyroid Association Low-to-Intermediate-Risk Papillary Thyroid Carcinoma.
    Otolaryngol Head Neck Surg. 2025 Sep 2. doi: 10.1002/ohn.70009.
    PubMed         Abstract available


    PLoS Genet

  32. FURUDATE K, Kasai S, Yoshizawa T, Sasaki Y, et al
    Spatial colocalization and molecular crosstalk of myofibroblastic CAFs and tumor cells shape lymph node metastasis in oral squamous cell carcinoma.
    PLoS Genet. 2025;21:e1011791.
    PubMed         Abstract available


    PLoS One

  33. PACHECO MCD, Prado AHDR, da Costa DV, de Arantes LC, et al
    Survival of dental implants in irradiated head and neck cancer patients compared to non-irradiated patients: An umbrella review.
    PLoS One. 2025;20:e0324388.
    PubMed         Abstract available

  34. OCCOMORE-KENT LC, Stavropoulou C, Ward EC, Elkington C, et al
    Training and competency frameworks used in the preparation of healthcare professionals for head and neck cancer screening: A scoping review protocol.
    PLoS One. 2025;20:e0330664.
    PubMed         Abstract available

  35. KHAN A, Fawzy WMS, Habib SS, Sultan M, et al
    Integrated comparative analysis of T-staging of laryngeal carcinoma on parallel versus non-parallel vocal cord CT planes with its potential treatment pitfalls.
    PLoS One. 2025;20:e0330389.
    PubMed         Abstract available


    Radiother Oncol

  36. GAU M, Alfaraj FA, Huang SH, O'Sullivan B, et al
    Unilateral vs bilateral neck irradiation: The importance of careful patient selection in tailoring radiation therapy for lateralized palatine-tonsil and non-palatine-tonsil oropharyngeal carcinoma.
    Radiother Oncol. 2025;210:111049.
    PubMed         Abstract available

  37. CHEUNG BMF, Yuen KK, Luk MY, Leung DKC, et al
    Lymphocyte nadir and recovery dynamics for locally advanced thoracic malignancies undergoing concurrent chemo-irradiation: Establishment of organs-at-risk constraints.
    Radiother Oncol. 2025;210:111009.
    PubMed         Abstract available


    Thyroid

  38. CHEN T, Li X, Hong D, Yin L, et al
    Targeting B7-H3 in Cancer-Associated Fibroblasts Using Nanosystems Suppresses Anaplastic Thyroid Carcinoma Progression.
    Thyroid. 2025 Sep 3. doi: 10.1177/10507256251372644.
    PubMed         Abstract available

  39. ZHANG J, Castroneves LA, Lindsey SC, Han R, et al
    Do Prognostic Differences Exist Among High-Risk RET Mutations? A Comparison of Outcomes Between the RET C634R and Other C634 Mutations in Hereditary Medullary Thyroid Carcinoma.
    Thyroid. 2025 Sep 3. doi: 10.1177/10507256251372196.
    PubMed         Abstract available


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