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  Head and Neck Cancer

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Articles published in Cancer Res

Retrieve available abstracts of 29 articles:
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Single Articles


    September 2025
  1. ZHANG D, Hu J, Zhu G, Liu C, et al
    CRB2 Activates an Epigenetic Axis to Promote Ferroptosis in Head and Neck Squamous Cell Carcinoma.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-24-3866.
    PubMed     Abstract available


  2. OLEINIK NV, Atilgan FC, Kassir MF, Lee HG, et al
    Ceramide-Induced Metabolic Stress Depletes Fumarate and Drives Mitophagy to Mediate Tumor Suppression.
    Cancer Res. 2025;85:3313-3334.
    PubMed     Abstract available


    August 2025
  3. ROY S, Miyauchi S, Jones RN, Kim SS, et al
    HPV E5 Mediates Resistance to Chemotherapy and Radiation by Promoting a Stem Cell-Like Phenotype in Head and Neck Squamous Cell Carcinoma.
    Cancer Res. 2025 Aug 21. doi: 10.1158/0008-5472.CAN-24-3989.
    PubMed     Abstract available


  4. CONTICELLI D, Volante M, Pietrantonio F, Orru C, et al
    AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer.
    Cancer Res. 2025;85:3111-3122.
    PubMed     Abstract available


    June 2025
  5. ZHANG Y, Li J, Guo X, Gao Z, et al
    Tumor-Specific MHC-II Activates CD4+ and CD8+ T cells in Head and Neck Squamous Cell Carcinoma to Boost Immunotherapy Efficacy.
    Cancer Res. 2025 Jun 20. doi: 10.1158/0008-5472.CAN-24-4383.
    PubMed     Abstract available


  6. KOSHIZUKA K, Wu X, Sato K, Vo PTT, et al
    Genome-Wide CRISPR Screening Reveals that mTOR Inhibition Initiates Ferritinophagy and Ferroptosis in Head and Neck Cancer.
    Cancer Res. 2025 Jun 6. doi: 10.1158/0008-5472.CAN-24-3785.
    PubMed     Abstract available


  7. YANG J, Chen F, Fu Z, Yang F, et al
    Blocking the TCA Cycle in Cancer Cells Potentiates CD36+ T-cell-Mediated Antitumor Immunity by Suppressing ER Stress-Associated THBS2 Signaling.
    Cancer Res. 2025;85:2014-2026.
    PubMed     Abstract available


    May 2025
  8. ZHENG Y, Chen Y, Meng X, Zhang L, et al
    FADD Functions as an Oncogene in Chr11q13.3-Amplified Head and Neck Squamous Cell Carcinoma.
    Cancer Res. 2025;85:1909-1927.
    PubMed     Abstract available


  9. MIMURA K, Yoshida K
    The Genetic Footprint of Tobacco Smoking: Unraveling the Mutational Signatures in Head and Neck Cancer.
    Cancer Res. 2025 May 12. doi: 10.1158/0008-5472.CAN-25-1990.
    PubMed     Abstract available


    April 2025
  10. UM JH, Zheng Y, Mao Q, Nam C, et al
    Genomic and Single-Cell Analyses Characterize Patient-Derived Tumor Organoids to Enable Personalized Therapy for Head and Neck Squamous Cell Carcinoma.
    Cancer Res. 2025 Apr 22. doi: 10.1158/0008-5472.CAN-24-2850.
    PubMed     Abstract available


  11. ZHAN J, Li M, Li L, Zeng TT, et al
    Targeting LTBP2 Derived from Cancer-Associated Fibroblasts Sensitizes Esophageal Squamous Cell Carcinoma to Chemotherapy.
    Cancer Res. 2025 Apr 17. doi: 10.1158/0008-5472.CAN-24-1816.
    PubMed     Abstract available


  12. NIU S, Ma J, Liu S, Li Y, et al
    Cis-regulatory Alterations in FOXP4 Modulate Esophageal Cancer Susceptibility Induced by Chronic Alcohol Exposure.
    Cancer Res. 2025 Apr 14. doi: 10.1158/0008-5472.CAN-24-3839.
    PubMed     Abstract available


  13. MENG L, Wu H, Wu J, Ding P, et al
    Aberrant CircTMEM45A Facilitates Inflammatory Progression of Esophageal Squamous Cell Carcinoma through m5C-Mediated NLRP3 Activation.
    Cancer Res. 2025 Apr 11. doi: 10.1158/0008-5472.CAN-24-4154.
    PubMed     Abstract available


    December 2024
  14. OU Z, Zhu L, Chen X, Liu T, et al
    Hypoxia-Induced Senescent Fibroblasts Secrete IGF1 to Promote Cancer Stemness in Esophageal Squamous Cell Carcinoma.
    Cancer Res. 2024 Dec 11. doi: 10.1158/0008-5472.CAN-24-1185.
    PubMed     Abstract available


    November 2024
  15. ZHANG J, Ni Z, Zhang Y, Guo Y, et al
    DAZAP1 Phase Separation Regulates Mitochondrial Metabolism to Facilitate Invasion and Metastasis of Oral Squamous Cell Carcinoma.
    Cancer Res. 2024;84:3818-3833.
    PubMed     Abstract available


  16. PLITT G, Brewer T, Yehia L, Rabinowitz L, et al
    The Genomic Landscape of Benign and Malignant Thyroid Tumors from Individuals Carrying Germline PTEN Variants Is Distinct from Sporadic Thyroid Cancers.
    Cancer Res. 2024;84:3657-3668.
    PubMed     Abstract available


    August 2024
  17. ZHOU L, Tian J, Wang K, Ma Y, et al
    Targeting Galectin-1 Overcomes Paclitaxel Resistance in Esophageal Squamous Cell Carcinoma.
    Cancer Res. 2024 Aug 26. doi: 10.1158/0008-5472.CAN-23-2241.
    PubMed     Abstract available


    July 2024
  18. YANG J, Chen F, Lang L, Yang F, et al
    Therapeutic Targeting of the GLS1-c-Myc Positive Feedback Loop Suppresses Glutaminolysis and Inhibits Progression of Head and Neck Cancer.
    Cancer Res. 2024 Jul 18. doi: 10.1158/0008-5472.CAN-24-0254.
    PubMed     Abstract available


  19. GNANAPRAGASAM A, Kirbizakis E, Li A, White KH, et al
    HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer.
    Cancer Res. 2024;84:2377-2389.
    PubMed     Abstract available


  20. DIAO P, Dai Y, Wang A, Bu X, et al
    Integrative multi-omics analyses identify molecular subtypes of head and neck squamous cell carcinoma with distinct therapeutic vulnerabilities.
    Cancer Res. 2024 Jul 3. doi: 10.1158/0008-5472.CAN-23-3594.
    PubMed     Abstract available


  21. LI B, Hao Y, He H, Fan Y, et al
    CD47-SIRPalpha Blockade Sensitizes Head and Neck Squamous Cell Carcinoma to Cetuximab by Enhancing Macrophage Adhesion to Cancer Cells.
    Cancer Res. 2024 Jul 3. doi: 10.1158/0008-5472.CAN-24-0176.
    PubMed     Abstract available


    May 2024
  22. BAKER AM, Nageswaran G, Nenclares P, Ronel T, et al
    FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA.
    Cancer Res. 2024;84:1560-1569.
    PubMed     Abstract available


  23. MENG X, Zheng Y, Zhang L, Liu P, et al
    Single-cell analyses reveal the metabolic heterogeneity and plasticity of the tumor microenvironment during head and neck squamous cell carcinoma progression.
    Cancer Res. 2024 May 8. doi: 10.1158/0008-5472.CAN-23-1344.
    PubMed     Abstract available


    January 2024
  24. LI C, Guo H, Zhai P, Yan M, et al
    Spatial and Single-Cell Transcriptomics Reveal a Cancer-Associated Fibroblast Subset in HNSCC That Restricts Infiltration and Antitumor Activity of CD8+ T Cells.
    Cancer Res. 2024;84:258-275.
    PubMed     Abstract available


    December 2023
  25. SHI Q, Xu G, Jiang Y, Yang J, et al
    Phospholipase PLCE1 promotes transcription and phosphorylation of MCM7 to drive tumor progression in esophageal cancer.
    Cancer Res. 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-1633.
    PubMed     Abstract available


    October 2023
  26. SMITH AE, Chan S, Wang Z, McCloskey A, et al
    Tipifarnib Potentiates the Antitumor Effects of PI3Kalpha Inhibition in PIK3CA- and HRAS-Dysregulated HNSCC via Convergent Inhibition of mTOR Activity.
    Cancer Res. 2023;83:3252-3263.
    PubMed     Abstract available


  27. LEE RH, Johnson DE, Grandis JR
    To Tip or Not to Tip: A New Combination for Precision Medicine in Head and Neck Cancer.
    Cancer Res. 2023;83:3162-3164.
    PubMed     Abstract available


    September 2023
  28. SFANOS KS
    Intratumoral Bacteria as Mediators of Cancer Immunotherapy Response.
    Cancer Res. 2023;83:2985-2986.
    PubMed     Abstract available


  29. ARBORE G, Albarello L, Bucci G, Punta M, et al
    Preexisting Immunity Drives the Response to Neoadjuvant Chemotherapy in Esophageal Adenocarcinoma.
    Cancer Res. 2023;83:2873-2888.
    PubMed     Abstract available


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