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Hepatitis

Free Subscription Articles published in Gut Retrieve available abstracts of 70 articles: HTML format

Single Articles

May 2026
1. CAO M, Wei F, Georges D, Alberts CJ, et al
   Hepatocellular carcinoma attributable to hepatitis B, hepatitis C and other risk factors at global, regional and national levels: an updated systematic review and meta-analysis.
   Gut. 2026 May 14:gutjnl-2025-337838. doi: 10.1136/gutjnl-2025-337838.
   PubMed     Abstract available
   
   
   
2. CHEN X, Liu X, Xu T, Wang Y, et al
   Engineered virus-hunter vaccine overcomes HBV immune tolerance.
   Gut. 2026;75:1211-1225.
   PubMed     Abstract available
   
   
   
3. BERTOLETTI A, Le Bert N
   CD16(+) gammadelta T cells and antibody-dependent cellular cytotoxicity: a new axis of immune control in hepatitis B virus infection?
   Gut. 2026 May 11:gutjnl-2026-338954. doi: 10.1136/gutjnl-2026-338954.
   PubMed    
   
   
   April 2026
4. MOHAMED A, Guerra Veloz M, Greenland L, Francois S, et al
   The UK experience with hepatitis B immunoglobulin use following liver transplantation: wide variation in practice despite evidence supporting cost-effective HBIG-free prophylaxis.
   Gut. 2026 Apr 27:gutjnl-2025-337965. doi: 10.1136/gutjnl-2025-337965.
   PubMed     Abstract available
   
   
   
5. LAU DT, Kim ES, Wang Z, King WC, et al
   Differential intrahepatic integrated HBV DNA patterns between HBeAg-positive and HBeAg-negative chronic hepatitis B.
   Gut. 2026 Apr 24:gutjnl-2025-337127. doi: 10.1136/gutjnl-2025-337127.
   PubMed     Abstract available
   
   
   
6. SCHROTER PE, Steppich K, Fernandez Carrera L, Song Z, et al
   CD16(+) gammadelta T cells mediate antibody-dependent cellular cytotoxicity and associate with viral control in chronic hepatitis B virus infection.
   Gut. 2026 Apr 15:gutjnl-2025-337640. doi: 10.1136/gutjnl-2025-337640.
   PubMed     Abstract available
   
   
   
7. GOUTTENOIRE J, Meuleman P
   Fluorescent virus lights up on a new drug for chronic hepatitis E.
   Gut. 2026 Apr 11:gutjnl-2026-338626. doi: 10.1136/gutjnl-2026-338626.
   PubMed    
   
   
   March 2026
8. PARLATI L, Bourliere M
   Steatosis severity and metabolic fingerprints after HCV eradication: toward an individualised approach to HCC surveillance after HCV cure.
   Gut. 2026 Mar 11:gutjnl-2026-338140. doi: 10.1136/gutjnl-2026-338140.
   PubMed    
   
   
   
9. HU J, Liu T, Klohn M, Freistaedter A, et al
   Nucleotide analogue bemnifosbuvir inhibits hepatitis E virus replication in preclinical models.
   Gut. 2026 Mar 6:gutjnl-2025-336714. doi: 10.1136/gutjnl-2025-336714.
   PubMed     Abstract available
   
   
   
10. WU W, Gao Q, Hai S, Li X, et al
    Impairment of Rab7-dependent STING degradation hampers HBV replication but accelerates disease progression in chronic hepatitis B comorbid with MASLD.
    Gut. 2026 Mar 3:gutjnl-2026-338065. doi: 10.1136/gutjnl-2026-338065.
    PubMed     Abstract available
    
    
    
11. WENG D, Chen J, Lin C
    Absolute risk stratification of HCC after HCV cure in MASLD: do advanced steatosis and dysglycaemia add beyond liver stiffness?
    Gut. 2026 Mar 2:gutjnl-2026-338294. doi: 10.1136/gutjnl-2026-338294.
    PubMed    
    
    
    February 2026
12. BARTOSCH B, Lauer GM
    Catch me if you can! Is there protection from HCV (re)infection?
    Gut. 2026 Feb 11:gutjnl-2025-337209. doi: 10.1136/gutjnl-2025-337209.
    PubMed    
    
    
    January 2026
13. CORNBERG M, Lampertico P
    Real-world evidence supports earlier treatment in HBeAg-positive but not HBeAg-negative chronic hepatitis B virus infection.
    Gut. 2026 Jan 28:gutjnl-2025-337281. doi: 10.1136/gutjnl-2025-337281.
    PubMed    
    
    
    
14. CHANG YP, Chen YC, Cheng PN, Fang YJ, et al
    Steatosis grade and cardiometabolic burden as determinants of hepatocellular carcinoma risk after hepatitis C cure in patients with metabolic dysfunction-associated steatotic liver disease.
    Gut. 2026 Jan 20:gutjnl-2025-337275. doi: 10.1136/gutjnl-2025-337275.
    PubMed     Abstract available
    
    
    
15. LIANG X, Luo J, Zhou Q, Xin J, et al
    Single-cell multimodal analysis reveals the dynamic immunopathogenesis of HBV-ACLF progression.
    Gut. 2026;75:367-381.
    PubMed     Abstract available
    
    
    December 2025
16. HE T, Chen M, Liu M, Zhang L, et al
    Twenty-four-week anti-PD-1 antibody regimen promoted HBsAg reduction and concurrently enhanced HBV-specific T cell responses in patients with chronic hepatitis B.
    Gut. 2025 Dec 24:gutjnl-2025-336655. doi: 10.1136/gutjnl-2025-336655.
    PubMed     Abstract available
    
    
    
17. SCHWINGE D
    Hepatocyte guardian: A20 restrains ferroptosis in autoimmune hepatitis.
    Gut. 2025 Dec 24:gutjnl-2025-337347. doi: 10.1136/gutjnl-2025-337347.
    PubMed    
    
    
    
18. LENS S, Burton AR, Davies J, Locatelli M, et al
    Tracking B cell immunity during perturbation of hepatitis B infection induced by treatment withdrawal.
    Gut. 2025 Dec 19:gutjnl-2024-333309. doi: 10.1136/gutjnl-2024-333309.
    PubMed     Abstract available
    
    
    
19. WANG J, Zhang S, Chen Y, Fan T, et al
    Serum thrombospondin-2 as a non-invasive biomarker for liver fibrosis in chronic hepatitis B.
    Gut. 2025 Dec 17:gutjnl-2025-336665. doi: 10.1136/gutjnl-2025-336665.
    PubMed    
    
    
    
20. CHU CM, Liaw YF
    Nucleos(t)ide analogue therapy for EASL immune-tolerant phase hepatitis B.
    Gut. 2025 Dec 3:gutjnl-2025-337558. doi: 10.1136/gutjnl-2025-337558.
    PubMed    
    
    
    November 2025
21. LIN C, Huang Y, Ran N, Liu J, et al
    Therapeutic inhibition of HBsAg and HBV cccDNA through a novel phased combination treatment: glycine and interferon-alpha.
    Gut. 2025;74:2035-2049.
    PubMed     Abstract available
    
    
    
22. CHEN Y, Li W, Wang S, Wang H, et al
    A20-mediated KEAP1 ubiquitination orchestrates hepatocyte ferroptosis to ameliorate autoimmune hepatitis.
    Gut. 2025 Nov 4:gutjnl-2025-336363. doi: 10.1136/gutjnl-2025-336363.
    PubMed     Abstract available
    
    
    
23. KENNEDY PTF, Fung S, Buti M, Yilmaz G, et al
    Peginterferon alpha-2a add-on to siRNA JNJ-73763989 in untreated patients with HBeAg-positive chronic hepatitis B virus (HBV) infection: the phase 2 REEF-IT study.
    Gut. 2025 Nov 4:gutjnl-2025-336592. doi: 10.1136/gutjnl-2025-336592.
    PubMed     Abstract available
    
    
    October 2025
24. TANG S, Huang T, Tang R, Lin K, et al
    EASL 2025 indications revisited: phase-specific outcomes with and without nucleos(t)ide analogue therapy in chronic hepatitis B virus infection.
    Gut. 2025 Oct 28:gutjnl-2025-335449. doi: 10.1136/gutjnl-2025-335449.
    PubMed     Abstract available
    
    
    
25. WANG J, Fan T, Zhu L, Zhang S, et al
    Profiles of quantitative hepatitis B surface antigen in patients with chronic hepatitis B.
    Gut. 2025 Oct 23:gutjnl-2025-336924. doi: 10.1136/gutjnl-2025-336924.
    PubMed    
    
    
    
26. CHUMBE AL, van den Aardweg SMD, Boyd A, Grobben M, et al
    Characteristics of an antibody profile associated with protection against hepatitis C virus reinfection in a high-risk cohort.
    Gut. 2025 Oct 23:gutjnl-2025-336302. doi: 10.1136/gutjnl-2025-336302.
    PubMed     Abstract available
    
    
    
27. LIU F, Liu T, Wu X, Yu Z, et al
    iPSC-induced multilineage liver organoids, small intestinal organoids and brain organoids sustain pangenotype hepatitis E virus propagation.
    Gut. 2025 Oct 21:gutjnl-2025-336105. doi: 10.1136/gutjnl-2025-336105.
    PubMed     Abstract available
    
    
    
28. HUANG R, Trinh HN, Yasuda S, Chau A, et al
    Differential HCC risk among HBV indeterminate types at baseline and by phase transition.
    Gut. 2025;74:1873-1882.
    PubMed     Abstract available
    
    
    
29. XU X, Chen J, Yu X, Li Z, et al
    Single-cell analysis identifies RETN(+) monocyte-derived Resistin as a therapeutic target in hepatitis B virus-related acute-on-chronic liver failure.
    Gut. 2025 Oct 6:gutjnl-2025-335998. doi: 10.1136/gutjnl-2025-335998.
    PubMed     Abstract available
    
    
    September 2025
30. TSENG TC, Yang HI, Kao JH
    Reply: Prevalence of serum HBsAg <100 IU/mL in inactive chronic hepatitis B.
    Gut. 2025 Sep 27:gutjnl-2025-336947. doi: 10.1136/gutjnl-2025-336947.
    PubMed    
    
    
    
31. TSENG TC, Yang HI, Kao JH
    Reply to: 'Rethinking "inactive chronic hepatitis B": should we treat patients with high HBsAg levels?'.
    Gut. 2025 Sep 27:gutjnl-2025-336618. doi: 10.1136/gutjnl-2025-336618.
    PubMed    
    
    
    August 2025
32. FAN T, Wang J, Zhu C, Wu C, et al
    Prevalence of serum HBsAg <100 IU/mL in inactive chronic hepatitis B.
    Gut. 2025 Aug 24:gutjnl-2025-336520. doi: 10.1136/gutjnl-2025-336520.
    PubMed    
    
    
    
33. SU CW, Liang YJ, Wu JC
    Unravelling the heterogeneous HCC risk in indeterminate chronic hepatitis B.
    Gut. 2025 Aug 18:gutjnl-2025-335915. doi: 10.1136/gutjnl-2025-335915.
    PubMed    
    
    
    
34. WU X, Quan D, Li W, Wisskirchen K, et al
    Clinical results of an HBV-specific T-cell receptor-T-cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma treated in an investigator-initiated, interventional trial.
    Gut. 2025 Aug 12:gutjnl-2025-335456. doi: 10.1136/gutjnl-2025-335456.
    PubMed     Abstract available
    
    
    
35. HUI RW, Wu TK, Ho KC, Leung RH, et al
    Large-scale profile study on hepatitis B surface antigen levels in chronic hepatitis B: implications for drug development targeting functional cure.
    Gut. 2025 Aug 5:gutjnl-2025-335219. doi: 10.1136/gutjnl-2025-335219.
    PubMed     Abstract available
    
    
    July 2025
36. SETO WK, Lok A
    Partial cure of chronic hepatitis B: potential implications for HCC surveillance?
    Gut. 2025 Jul 29:gutjnl-2025-336032. doi: 10.1136/gutjnl-2025-336032.
    PubMed    
    
    
    
37. CHEN J, You H, Lau G
    Rethinking 'Inactive Chronic Hepatitis B': should we treat patients with high HBsAg levels?
    Gut. 2025 Jul 23:gutjnl-2025-336373. doi: 10.1136/gutjnl-2025-336373.
    PubMed    
    
    
    
38. GUILLOT A, Pose E
    Hepatocyte senescence in alcohol-associated hepatitis: epiphenomenon or disease-driving mechanism?
    Gut. 2025 Jul 17:gutjnl-2025-335271. doi: 10.1136/gutjnl-2025-335271.
    PubMed    
    
    
    June 2025
39. TSENG TC, Huang SC, Pan MH, Liu CJ, et al
    Hepatitis B surface antigen level identifies patients with inactive chronic hepatitis B from Asia with HCC risk below surveillance threshold.
    Gut. 2025 Jun 20:gutjnl-2025-334911. doi: 10.1136/gutjnl-2025-334911.
    PubMed     Abstract available
    
    
    May 2025
40. LI H, Song M, Hylemon PB, Zhou H, et al
    LECT2-PHB2 axis: a new mechanistic insight and therapeutic opportunity in alcohol-associated hepatitis.
    Gut. 2025 May 13:gutjnl-2025-335259. doi: 10.1136/gutjnl-2025-335259.
    PubMed    
    
    
    April 2025
41. ROTTELE F, Zollner A, Mogler C, Yuksel M, et al
    Characteristic immune cell interactions in livers of children with acute hepatitis revealed by spatial single-cell analysis identify a possible postacute sequel of COVID-19.
    Gut. 2025 Apr 5:gutjnl-2024-333880. doi: 10.1136/gutjnl-2024-333880.
    PubMed     Abstract available
    
    
    
42. LURJE I, Tacke F
    Immune pathology in paediatric acute hepatitis of unknown origin - uncovering the link to COVID-19.
    Gut. 2025 Apr 5:gutjnl-2024-334453. doi: 10.1136/gutjnl-2024-334453.
    PubMed    
    
    
    
43. GLEESON D, Bornand R, Brownlee A, Dhaliwal H, et al
    British Society of Gastroenterology guidelines for diagnosis and management of autoimmune hepatitis.
    Gut. 2025 Apr 1:gutjnl-2024-333171. doi: 10.1136/gutjnl-2024-333171.
    PubMed     Abstract available
    
    
    March 2025
44. XU H, Wu Z, Qin J, Li X, et al
    Stressed hepatocyte sustains alcohol-associated hepatitis progression by producing leukocyte cell-derived chemotaxin 2.
    Gut. 2025 Mar 26:gutjnl-2024-334318. doi: 10.1136/gutjnl-2024-334318.
    PubMed     Abstract available
    
    
    
45. RODRIGO-TORRES D, Kilpatrick AM, Ferreira-Gonzalez S, Aird RE, et al
    Longitudinal paired liver biopsies and transcriptome profiling in alcohol-associated hepatitis reveal dynamic changes in cellular senescence.
    Gut. 2025 Mar 23:gutjnl-2024-334094. doi: 10.1136/gutjnl-2024-334094.
    PubMed     Abstract available
    
    
    December 2024
46. LAMPERTICO P, Anolli MP, Roulot D, Wedemeyer H, et al
    Antiviral therapy for chronic hepatitis delta: new insights from clinical trials and real-life studies.
    Gut. 2024 Dec 11:gutjnl-2024-332597. doi: 10.1136/gutjnl-2024-332597.
    PubMed     Abstract available
    
    
    October 2024
47. PAN DZ, Soulette CM, Aggarwal A, Han D, et al
    Effects of tenofovir disoproxil fumarate on intrahepatic viral burden and liver immune microenvironment in patients with chronic hepatitis B.
    Gut. 2024 Oct 8:gutjnl-2024-332526. doi: 10.1136/gutjnl-2024-332526.
    PubMed     Abstract available
    
    
    
48. LIU T, Li J, Yin X, Lu F, et al
    Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system.
    Gut. 2024 Oct 1:gutjnl-2024-332784. doi: 10.1136/gutjnl-2024-332784.
    PubMed     Abstract available
    
    
    September 2024
49. BROL MJ, Canbay A, Trebicka J
    Alcohol-associated hepatitis: a neutrophile disease?
    Gut. 2024 Sep 24:gutjnl-2024-333222. doi: 10.1136/gutjnl-2024-333222.
    PubMed    
    
    
    
50. MAK LY, Wooddell CI, Lenz O, Schluep T, et al
    Long-term hepatitis B surface antigen response after finite treatment of ARC-520 or JNJ-3989.
    Gut. 2024 Sep 12:gutjnl-2024-333026. doi: 10.1136/gutjnl-2024-333026.
    PubMed     Abstract available
    
    
    
51. FAN R, Zhao S, Niu J, Ma H, et al
    High accuracy model for HBsAg loss based on longitudinal trajectories of serum qHBsAg throughout long-term antiviral therapy.
    Gut. 2024;73:1725-1736.
    PubMed     Abstract available
    
    
    July 2024
52. VECCHI A, Rossi M, Tiezzi C, Fisicaro P, et al
    HBcrAg values may predict virological and immunological responses to pegIFN-alpha in NUC-suppressed HBeAg-negative chronic hepatitis B.
    Gut. 2024 Jul 20:gutjnl-2024-332290. doi: 10.1136/gutjnl-2024-332290.
    PubMed     Abstract available
    
    
    
53. KREIMEYER H, Gonzalez CG, Fondevila MF, Hsu CL, et al
    Faecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis.
    Gut. 2024 Jul 20:gutjnl-2024-332730. doi: 10.1136/gutjnl-2024-332730.
    PubMed     Abstract available
    
    
    
54. BAUMERT T, Urbanek-Quaing M, Cornberg M
    Immunomodulation and entry inhibition: selgantolimod's double punch against hepatitis B virus.
    Gut. 2024 Jul 5:gutjnl-2024-332679. doi: 10.1136/gutjnl-2024-332679.
    PubMed    
    
    
    
55. KAMAR N, Marion O, Abravanel F, Esposito L, et al
    Porcine-derived pancreatic enzyme replacement therapy: a cause of hepatitis E virus transmission?
    Gut. 2024 Jul 2:gutjnl-2024-332744. doi: 10.1136/gutjnl-2024-332744.
    PubMed    
    
    
    June 2024
56. ZHOU J, Liu K, Pan Q
    Porcine-derived pancreatic enzyme replacement therapy linking to chronic hepatitis E: broad implications.
    Gut. 2024 Jun 12:gutjnl-2024-332975. doi: 10.1136/gutjnl-2024-332975.
    PubMed    
    
    
    May 2024
57. FRERICKS N, Kinast V, Steinmann E
    Potential risk of porcine-derived pancreatic enzyme medication for the cross-species transmission of hepatitis E virus.
    Gut. 2024 May 31:gutjnl-2024-332577. doi: 10.1136/gutjnl-2024-332577.
    PubMed    
    
    
    
58. VO-QUANG E, Pawlotsky JM
    'Unusual' HCV genotype subtypes: origin, distribution, sensitivity to direct-acting antiviral drugs and behaviour on antiviral treatment and retreatment.
    Gut. 2024 May 23:gutjnl-2024-332177. doi: 10.1136/gutjnl-2024-332177.
    PubMed     Abstract available
    
    
    
59. ROCA SUAREZ AA, Plissonnier ML, Grand X, Michelet M, et al
    TLR8 agonist selgantolimod regulates Kupffer cell differentiation status and impairs HBV entry into hepatocytes via an IL-6-dependent mechanism.
    Gut. 2024 May 2:gutjnl-2023-331396. doi: 10.1136/gutjnl-2023-331396.
    PubMed     Abstract available
    
    
    April 2024
60. THORNTON CS, Waddell BJ, Congly SE, Svishchuk J, et al
    Porcine-derived pancreatic enzyme replacement therapy may be linked to chronic hepatitis E virus infection in cystic fibrosis lung transplant recipients.
    Gut. 2024 Apr 15:gutjnl-2023-330602. doi: 10.1136/gutjnl-2023-330602.
    PubMed     Abstract available
    
    
    January 2024
61. HE T, Zhang D
    Non-linear association of baseline viral load with on-treatment hepatocellular carcinoma risk in chronic hepatitis B: still needs further discussion.
    Gut. 2024 Jan 22:gutjnl-2023-331443. doi: 10.1136/gutjnl-2023-331443.
    PubMed    
    
    
    
62. 
    Correction: Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies.
    Gut. 2024;73:e1.
    PubMed    
    
    
    
63. LIN C, Luo L, Xun Z, Zhu C, et al
    Novel function of MOTS-c in mitochondrial remodelling contributes to its antiviral role during HBV infection.
    Gut. 2024;73:338-349.
    PubMed     Abstract available
    
    
    November 2023
64. WANG Y, Li Q, Li C, Wang C, et al
    Chimeric antigen receptors of HBV envelope proteins inhibit hepatitis B surface antigen secretion.
    Gut. 2023 Nov 16:gutjnl-2023-330537. doi: 10.1136/gutjnl-2023-330537.
    PubMed     Abstract available
    
    
    
65. YU X, Gong Q, Yu D, Chen Y, et al
    Spatial transcriptomics reveals a low extent of transcriptionally active hepatitis B virus integration in patients with HBsAg loss.
    Gut. 2023 Nov 15:gutjnl-2023-330577. doi: 10.1136/gutjnl-2023-330577.
    PubMed     Abstract available
    
    
    October 2023
66. TESTONI B, Scholtes C, Plissonnier ML, Paturel A, et al
    Quantification of circulating HBV RNA expressed from intrahepatic cccDNA in untreated and NUC treated patients with chronic hepatitis B.
    Gut. 2023 Oct 25:gutjnl-2023-330644. doi: 10.1136/gutjnl-2023-330644.
    PubMed     Abstract available
    
    
    
67. CHOI WM, Kim GA, Choi J, Choi GH, et al
    Non-linear association of baseline viral load with on-treatment hepatocellular carcinoma risk in chronic hepatitis B.
    Gut. 2023 Oct 9:gutjnl-2023-330225. doi: 10.1136/gutjnl-2023-330225.
    PubMed     Abstract available
    
    
    
68. LIU Z, Lin C, Mao X, Guo C, et al
    Changing prevalence of chronic hepatitis B virus infection in China between 1973 and 2021: a systematic literature review and meta-analysis of 3740 studies and 231 million people.
    Gut. 2023 Oct 5:gutjnl-2023-330691. doi: 10.1136/gutjnl-2023-330691.
    PubMed     Abstract available
    
    
    September 2023
69. LE BERT N, Fisicaro P
    Enolase: a metabolic checkpoint behind diverse exhaustion stages of CD8+ T cells in chronic HBV and HCV.
    Gut. 2023 Sep 6:gutjnl-2023-330541. doi: 10.1136/gutjnl-2023-330541.
    PubMed    
    
    
    January 2023
70. HENDRIKX T, Lang S, Rajcic D, Wang Y, et al
    Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice.
    Gut. 2023 Jan 23:gutjnl-2022-328265. doi: 10.1136/gutjnl-2022-328265.
    PubMed     Abstract available
    
    

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