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Articles published in PLoS Pathog

Retrieve available abstracts of 66 articles:
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Single Articles


    July 2021
  1. LI Y, Luo G
    Human low-density lipoprotein receptor plays an important role in hepatitis B virus infection.
    PLoS Pathog. 2021;17:e1009722.
    PubMed     Abstract available


  2. OLESEN CH, Augestad EH, Troise F, Bukh J, et al
    In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus.
    PLoS Pathog. 2021;17:e1009720.
    PubMed     Abstract available


    May 2021
  3. BAUDI I, Isogawa M, Moalli F, Onishi M, et al
    Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen.
    PLoS Pathog. 2021;17:e1009228.
    PubMed     Abstract available


    April 2021
  4. SCHOBEL A, Nguyen-Dinh V, Schumann GG, Herker E, et al
    Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells.
    PLoS Pathog. 2021;17:e1009496.
    PubMed     Abstract available


    March 2021
  5. WU YH, Yang Y, Chen CH, Hsiao CJ, et al
    Aerobic glycolysis supports hepatitis B virus protein synthesis through interaction between viral surface antigen and pyruvate kinase isoform M2.
    PLoS Pathog. 2021;17:e1008866.
    PubMed     Abstract available


    February 2021
  6. EL COSTA H, Gouilly J, Abravanel F, Bahraoui E, et al
    Effector memory CD8 T cell response elicits Hepatitis E Virus genotype 3 pathogenesis in the elderly.
    PLoS Pathog. 2021;17:e1009367.
    PubMed     Abstract available


    January 2021
  7. XI J, Luckenbaugh L, Hu J
    Multiple roles of PP2A binding motif in hepatitis B virus core linker and PP2A in regulating core phosphorylation state and viral replication.
    PLoS Pathog. 2021;17:e1009230.
    PubMed     Abstract available


  8. WELLS AI, Grimes KA, Kim K, Branche E, et al
    Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice.
    PLoS Pathog. 2021;17:e1009252.
    PubMed     Abstract available


    December 2020
  9. DUCROUX A, Benhenda S, Riviere L, Semmes OJ, et al
    Correction: The Tudor Domain Protein Spindlin1 Is Involved in Intrinsic Antiviral Defense against Incoming Hepatitis B Virus and Herpes Simplex Virus Type 1.
    PLoS Pathog. 2020;16:e1009135.
    PubMed     Abstract available


    November 2020
  10. CHABROLLES H, Auclair H, Vegna S, Lahlali T, et al
    Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production.
    PLoS Pathog. 2020;16:e1008593.
    PubMed     Abstract available


    October 2020
  11. LERCHER A, Popa AM, Viczenczova C, Kosack L, et al
    Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis.
    PLoS Pathog. 2020;16:e1008973.
    PubMed     Abstract available


  12. SHEN S, Xie Z, Cai D, Yu X, et al
    Biogenesis and molecular characteristics of serum hepatitis B virus RNA.
    PLoS Pathog. 2020;16:e1008945.
    PubMed     Abstract available


    September 2020
  13. SINGH KP, Zerbato JM, Zhao W, Braat S, et al
    Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection.
    PLoS Pathog. 2020;16:e1008744.
    PubMed     Abstract available


    August 2020
  14. TAHA TY, Anirudhan V, Limothai U, Loeb DD, et al
    Modulation of hepatitis B virus pregenomic RNA stability and splicing by histone deacetylase 5 enhances viral biosynthesis.
    PLoS Pathog. 2020;16:e1008802.
    PubMed     Abstract available


  15. CHEN TC, Tallo-Parra M, Cao QM, Kadener S, et al
    Host-derived circular RNAs display proviral activities in Hepatitis C virus-infected cells.
    PLoS Pathog. 2020;16:e1008346.
    PubMed     Abstract available


  16. CHEN Z, Engle RE, Shen CH, Zhao H, et al
    Distinct disease features in chimpanzees infected with a precore HBV mutant associated with acute liver failure in humans.
    PLoS Pathog. 2020;16:e1008793.
    PubMed     Abstract available


    July 2020
  17. TOMLINSON JE, Wolfisberg R, Fahnoe U, Sharma H, et al
    Equine pegiviruses cause persistent infection of bone marrow and are not associated with hepatitis.
    PLoS Pathog. 2020;16:e1008677.
    PubMed     Abstract available


  18. HU Z, Ban H, Zheng H, Liu M, et al
    Protein phosphatase 1 catalyzes HBV core protein dephosphorylation and is co-packaged with viral pregenomic RNA into nucleocapsids.
    PLoS Pathog. 2020;16:e1008669.
    PubMed     Abstract available


    June 2020
  19. ONO C, Fukuhara T, Li S, Wang J, et al
    Various miRNAs compensate the role of miR-122 on HCV replication.
    PLoS Pathog. 2020;16:e1008308.
    PubMed     Abstract available


  20. VIEYRES G, Reichert I, Carpentier A, Vondran FWR, et al
    The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly.
    PLoS Pathog. 2020;16:e1008554.
    PubMed     Abstract available


    May 2020
  21. JU X, Xiang G, Gong M, Yang R, et al
    Identification of functional cis-acting RNA elements in the hepatitis E virus genome required for viral replication.
    PLoS Pathog. 2020;16:e1008488.
    PubMed     Abstract available


    March 2020
  22. LUO J, Xi J, Gao L, Hu J, et al
    Role of Hepatitis B Virus Capsid Phosphorylation in Nucleocapsid Disassembly and Covalently Closed Circular DNA Formation.
    PLoS Pathog. 2020;16:e1008459.
    PubMed     Abstract available


    February 2020
  23. IMAM H, Kim GW, Mir SA, Khan M, et al
    Interferon-stimulated gene 20 (ISG20) selectively degrades N6-methyladenosine modified Hepatitis B Virus transcripts.
    PLoS Pathog. 2020;16:e1008338.
    PubMed     Abstract available


    December 2019
  24. SURESH M, Czerwinski S, Murreddu MG, Kallakury BV, et al
    Innate and adaptive immunity associated with resolution of acute woodchuck hepatitis virus infection in adult woodchucks.
    PLoS Pathog. 2019;15:e1008248.
    PubMed     Abstract available


    September 2019
  25. LEE JS, Tabata K, Twu WI, Rahman SM, et al
    RACK1 mediates rewiring of intracellular networks induced by hepatitis C virus infection.
    PLoS Pathog. 2019;15:e1008021.
    PubMed     Abstract available


    August 2019
  26. JOYCE MA, Berry-Wynne KM, Dos Santos T, Addison WR, et al
    HCV and flaviviruses hijack cellular mechanisms for nuclear STAT2 degradation: Up-regulation of PDLIM2 suppresses the innate immune response.
    PLoS Pathog. 2019;15:e1007949.
    PubMed     Abstract available


  27. QIAO L, Luo GG
    Human apolipoprotein E promotes hepatitis B virus infection and production.
    PLoS Pathog. 2019;15:e1007874.
    PubMed     Abstract available


    July 2019
  28. DOYLE EH, Rahman A, Aloman C, Klepper AL, et al
    Individual liver plasmacytoid dendritic cells are capable of producing IFNalpha and multiple additional cytokines during chronic HCV infection.
    PLoS Pathog. 2019;15:e1007935.
    PubMed     Abstract available


  29. HYUN J, McMahon RS, Lang AL, Edwards JS, et al
    HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells.
    PLoS Pathog. 2019;15:e1007883.
    PubMed     Abstract available


    June 2019
  30. ALBE JR, Boyles DA, Walters AW, Kujawa MR, et al
    Neutrophil and macrophage influx into the central nervous system are inflammatory components of lethal Rift Valley fever encephalitis in rats.
    PLoS Pathog. 2019;15:e1007833.
    PubMed     Abstract available


    May 2019
  31. KECK ZY, Pierce BG, Lau P, Lu J, et al
    Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design.
    PLoS Pathog. 2019;15:e1007772.
    PubMed     Abstract available


  32. MATA M, Neben S, Majzoub K, Carette J, et al
    Impact of a patient-derived hepatitis C viral RNA genome with a mutated microRNA binding site.
    PLoS Pathog. 2019;15:e1007467.
    PubMed     Abstract available


  33. CAO L, Yu B, Kong D, Cong Q, et al
    Functional expression and characterization of the envelope glycoprotein E1E2 heterodimer of hepatitis C virus.
    PLoS Pathog. 2019;15:e1007759.
    PubMed     Abstract available


    April 2019
  34. TANG L, Sheraz M, McGrane M, Chang J, et al
    DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA.
    PLoS Pathog. 2019;15:e1007742.
    PubMed     Abstract available


  35. CHANG KM, Traum D, Park JJ, Ho S, et al
    Distinct phenotype and function of circulating Vdelta1+ and Vdelta2+ gammadeltaT-cells in acute and chronic hepatitis B.
    PLoS Pathog. 2019;15:e1007715.
    PubMed     Abstract available


  36. RAJA R, Pareek A, Newar K, Dixit NM, et al
    Mutational pathway maps and founder effects define the within-host spectrum of hepatitis C virus mutants resistant to drugs.
    PLoS Pathog. 2019;15:e1007701.
    PubMed     Abstract available


  37. YANG F, Yu X, Zhou C, Mao R, et al
    Hepatitis B e antigen induces the expansion of monocytic myeloid-derived suppressor cells to dampen T-cell function in chronic hepatitis B virus infection.
    PLoS Pathog. 2019;15:e1007690.
    PubMed     Abstract available


    February 2019
  38. RODER AE, Vazquez C, Horner SM
    The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein.
    PLoS Pathog. 2019;15:e1007163.
    PubMed     Abstract available


  39. NEGASH AA, Olson RM, Griffin S, Gale M Jr, et al
    Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation.
    PLoS Pathog. 2019;15:e1007593.
    PubMed     Abstract available


    December 2018
  40. HEGER-STEVIC J, Zimmermann P, Lecoq L, Bottcher B, et al
    Hepatitis B virus core protein phosphorylation: Identification of the SRPK1 target sites and impact of their occupancy on RNA binding and capsid structure.
    PLoS Pathog. 2018;14:e1007488.
    PubMed     Abstract available


  41. GOUTTENOIRE J, Pollan A, Abrami L, Oechslin N, et al
    Palmitoylation mediates membrane association of hepatitis E virus ORF3 protein and is required for infectious particle secretion.
    PLoS Pathog. 2018;14:e1007471.
    PubMed     Abstract available


    November 2018
  42. LIANG Y, Cao X, Ding Q, Zhao Y, et al
    Correction: Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon signaling pathway.
    PLoS Pathog. 2018;14:e1007455.
    PubMed     Abstract available


    October 2018
  43. BAMFORD CGG, Aranday-Cortes E, Filipe IC, Sukumar S, et al
    A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages.
    PLoS Pathog. 2018;14:e1007307.
    PubMed     Abstract available


    September 2018
  44. MINGORANCE L, Castro V, Avila-Perez G, Calvo G, et al
    Host phosphatidic acid phosphatase lipin1 is rate limiting for functional hepatitis C virus replicase complex formation.
    PLoS Pathog. 2018;14:e1007284.
    PubMed     Abstract available


  45. ROSENBERG BR, Depla M, Freije CA, Gaucher D, et al
    Longitudinal transcriptomic characterization of the immune response to acute hepatitis C virus infection in patients with spontaneous viral clearance.
    PLoS Pathog. 2018;14:e1007290.
    PubMed     Abstract available


    July 2018
  46. SHANMUGAM S, Nichols AK, Saravanabalaji D, Welsch C, et al
    HCV NS5A dimer interface residues regulate HCV replication by controlling its self-interaction, hyperphosphorylation, subcellular localization and interaction with cyclophilin A.
    PLoS Pathog. 2018;14:e1007177.
    PubMed     Abstract available


  47. BRUENING J, Lasswitz L, Banse P, Kahl S, et al
    Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.
    PLoS Pathog. 2018;14:e1007111.
    PubMed     Abstract available


    June 2018
  48. KITAMURA K, Que L, Shimadu M, Koura M, et al
    Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus.
    PLoS Pathog. 2018;14:e1007124.
    PubMed     Abstract available


    May 2018
  49. LIU K, Luckenbaugh L, Ning X, Xi J, et al
    Multiple roles of core protein linker in hepatitis B virus replication.
    PLoS Pathog. 2018;14:e1007085.
    PubMed     Abstract available


  50. LIANG Y, Cao X, Ding Q, Zhao Y, et al
    Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon signaling pathway.
    PLoS Pathog. 2018;14:e1007075.
    PubMed     Abstract available


    April 2018
  51. DRAPPIER M, Jha BK, Stone S, Elliott R, et al
    A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.
    PLoS Pathog. 2018;14:e1006989.
    PubMed     Abstract available


    March 2018
  52. SEKHAR V, Pollicino T, Diaz G, Engle RE, et al
    Infection with hepatitis C virus depends on TACSTD2, a regulator of claudin-1 and occludin highly downregulated in hepatocellular carcinoma.
    PLoS Pathog. 2018;14:e1006916.
    PubMed     Abstract available


  53. DOUAM F, Fusil F, Enguehard M, Dib L, et al
    A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.
    PLoS Pathog. 2018;14:e1006908.
    PubMed     Abstract available


    February 2018
  54. BOUKADIDA C, Fritz M, Blumen B, Fogeron ML, et al
    NS2 proteases from hepatitis C virus and related hepaciviruses share composite active sites and previously unrecognized intrinsic proteolytic activities.
    PLoS Pathog. 2018;14:e1006863.
    PubMed     Abstract available


    January 2018
  55. YIN C, Goonawardane N, Stewart H, Harris M, et al
    A role for domain I of the hepatitis C virus NS5A protein in virus assembly.
    PLoS Pathog. 2018;14:e1006834.
    PubMed     Abstract available


    December 2017
  56. DENOLLY S, Mialon C, Bourlet T, Amirache F, et al
    The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.
    PLoS Pathog. 2017;13:e1006774.
    PubMed     Abstract available


  57. GOPAL R, Jackson K, Tzarum N, Kong L, et al
    Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis.
    PLoS Pathog. 2017;13:e1006735.
    PubMed     Abstract available


    October 2017
  58. YU Y, Scheel TKH, Luna JM, Chung H, et al
    miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence.
    PLoS Pathog. 2017;13:e1006694.
    PubMed     Abstract available


  59. KUMTHIP K, Yang D, Li NL, Zhang Y, et al
    Pivotal role for the ESCRT-II complex subunit EAP30/SNF8 in IRF3-dependent innate antiviral defense.
    PLoS Pathog. 2017;13:e1006713.
    PubMed     Abstract available


    September 2017
  60. WANG L, Kim JY, Liu HM, Lai MMC, et al
    HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication.
    PLoS Pathog. 2017;13:e1006609.
    PubMed     Abstract available


  61. GUO F, Zhao Q, Sheraz M, Cheng J, et al
    HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways.
    PLoS Pathog. 2017;13:e1006658.
    PubMed     Abstract available


    June 2017
  62. BENZINE T, Brandt R, Lovell WC, Yamane D, et al
    NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains.
    PLoS Pathog. 2017;13:e1006343.
    PubMed     Abstract available


    May 2017
  63. YIN X, Li X, Ambardekar C, Hu Z, et al
    Hepatitis E virus persists in the presence of a type III interferon response.
    PLoS Pathog. 2017;13:e1006417.
    PubMed     Abstract available


  64. ONO C, Fukuhara T, Motooka D, Nakamura S, et al
    Characterization of miR-122-independent propagation of HCV.
    PLoS Pathog. 2017;13:e1006374.
    PubMed     Abstract available


    April 2017
  65. LIU Y, Nie H, Mao R, Mitra B, et al
    Interferon-inducible ribonuclease ISG20 inhibits hepatitis B virus replication through directly binding to the epsilon stem-loop structure of viral RNA.
    PLoS Pathog. 2017;13:e1006296.
    PubMed     Abstract available


  66. ZHANG X, Zhu C, Wang T, Jiang H, et al
    GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
    PLoS Pathog. 2017;13:e1006321.
    PubMed     Abstract available


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