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By Bernd Sebastian Kamps and Andrea Melis

  Genetics

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Articles published in PLoS Comput Biol

Retrieve available abstracts of 128 articles:
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Single Articles


    April 2026
  1. ZHANG W, Yu Y, Zheng X, Shen J, et al
    Clustering single-cell multi-omics data via weighted distance penalty and adaptive consistent graph regularization.
    PLoS Comput Biol. 2026;22:e1014110.
    PubMed     Abstract available


  2. KAZEMI P, Coombe L, Warren RL, Birol I, et al
    ntStat: k-mer characterization using occurrence statistics in raw sequencing data.
    PLoS Comput Biol. 2026;22:e1014158.
    PubMed     Abstract available


  3. BORA A, McKenzie M, Ziemann M
    Ten common mistakes that could ruin your enrichment analysis.
    PLoS Comput Biol. 2026;22:e1014122.
    PubMed     Abstract available


  4. LI G, Jianhan F, Gu J, Wang Y, et al
    Systematic prioritization of potential therapeutic targets for glomerulonephritis using multi-omics Mendelian randomization.
    PLoS Comput Biol. 2026;22:e1014174.
    PubMed     Abstract available


    March 2026
  5. LIAO K, Du D, Li J, Huang J, et al
    Interpretable integration of unpaired multi-omics for Alzheimer's diagnosis via cross-modal transformer reconstruction.
    PLoS Comput Biol. 2026;22:e1014074.
    PubMed     Abstract available


  6. ZHAO M, Tang X, Li J, Liang C, et al
    MultiPert: An adversarial alignment and dual attention framework for single-cell multi-omics perturbation prediction.
    PLoS Comput Biol. 2026;22:e1014054.
    PubMed     Abstract available


  7. PUCCI N, Kaan AM, Ujcic-Voortman J, Verhoeff AP, et al
    Unique ecology of co-occurring functionally and phylogenetically undescribed species in the infant oral microbiome.
    PLoS Comput Biol. 2026;22:e1013185.
    PubMed     Abstract available


  8. YANG M, Huang ZA, Zheng Z, Liu Y, et al
    HiCMamba: Enhancing Hi-C resolution and identifying 3D genome structures with state space modeling.
    PLoS Comput Biol. 2026;22:e1014057.
    PubMed     Abstract available


  9. SOLEYMANI F, Razaghi-Moghadam Z, Nikoloski Z
    Accurate prediction of flux distributions compatible with metabolite concentration effects in genome-scale metabolic networks.
    PLoS Comput Biol. 2026;22:e1014066.
    PubMed     Abstract available


  10. ANTONOPOULOS K, Nordenstorm O, Nilsson A
    Zero-shot prediction of drug responses using biologically informed neural networks trained on phosphoproteomic timeseries.
    PLoS Comput Biol. 2026;22:e1014100.
    PubMed     Abstract available


  11. MARTIN EA, Patchigolla V, Fu AQ
    Approximate Bayesian inference of directed acyclic graphs in biology with flexible priors on edge states.
    PLoS Comput Biol. 2026;22:e1014039.
    PubMed     Abstract available


    February 2026
  12. GUO Y, Mallona I, Robinson MD, Li L, et al
    BiCLUM: Bilateral contrastive learning for unpaired single-cell multi-omics integration.
    PLoS Comput Biol. 2026;22:e1013932.
    PubMed     Abstract available


  13. HARTMAN E, Malmstrom J, Wallin J
    Degradation graphs reveal hidden proteolytic activity in peptidomes.
    PLoS Comput Biol. 2026;22:e1013972.
    PubMed     Abstract available


  14. BACON WA, Batut B, Srikakulam SK, Zierep P, et al
    Ten common misconceptions about Galaxy (and why they are wrong!).
    PLoS Comput Biol. 2026;22:e1013869.
    PubMed     Abstract available


  15. CHANTZI N, Mouratidis I, Georgakopoulos-Soares I
    Zimin patterns in genomes.
    PLoS Comput Biol. 2026;22:e1013909.
    PubMed     Abstract available


  16. BALOYAN A, Konecny T, Hovhannisyan E, Zadirako N, et al
    A topological map of the genetic components of grapevine-Admixture meets SOMmelier machine learning.
    PLoS Comput Biol. 2026;22:e1013882.
    PubMed     Abstract available


  17. COLBY JM, Krantz BA
    A dynamical anthrax toxin nanopore biosensor for high-fidelity single-peptide classification.
    PLoS Comput Biol. 2026;22:e1014019.
    PubMed     Abstract available


  18. ZHANG S, Lu Y, Li P, Wu J, et al
    CA-CAE: A deep learning-based multi-omics model for pan-cancer subtype classification and prognosis prediction.
    PLoS Comput Biol. 2026;22:e1014015.
    PubMed     Abstract available


  19. ZHOU H, Edelman B, Skolnick J
    MENDELSEEK: An algorithm that predicts mendelian genes and elucidates what makes them special.
    PLoS Comput Biol. 2026;22:e1013992.
    PubMed     Abstract available


    January 2026
  20. BURKE D, Raychaudhuri J, Chuong E, Taylor W, et al
    TEPEAK: A novel method for identifying and characterizing polymorphic transposable elements in non-model species populations.
    PLoS Comput Biol. 2026;22:e1013122.
    PubMed     Abstract available


  21. KARAGIANNIS TT, Chen Y, Bald S, Tai A, et al
    Integrative analysis across metagenomic taxonomic classifiers: A case study of the gut microbiome in aging and longevity in the Integrative Longevity Omics Study.
    PLoS Comput Biol. 2026;22:e1013883.
    PubMed     Abstract available


  22. PELLOW R, Comeron JM
    A wavelet-based approach generates quantitative, scale-free and hierarchical descriptions of 3D genome structures and new biological insights.
    PLoS Comput Biol. 2026;22:e1013887.
    PubMed     Abstract available


  23. ROY A, Zhang X
    Powerful large scale inference in high dimensional mediation analysis.
    PLoS Comput Biol. 2026;22:e1013880.
    PubMed     Abstract available


  24. MIAO J, Li D
    TEvarSim: A genome simulator for transposable element (TE) variants.
    PLoS Comput Biol. 2026;22:e1013933.
    PubMed     Abstract available


  25. KRZYNOWEK A, Snoeks J, Faust K
    PlasticEnz: An integrated database and screening tool combining homology and machine learning to identify plastic-degrading enzymes in meta-omics datasets.
    PLoS Comput Biol. 2026;22:e1013892.
    PubMed     Abstract available


  26. WEN G, Li L
    CoFormerSurv: Collaborative transformer for multi-omics survival analysis.
    PLoS Comput Biol. 2026;22:e1013875.
    PubMed     Abstract available


    December 2025
  27. CHICCO D, Jurman G
    Comment on "Using genomic data and machine learning to predict antibiotic resistance: A tutorial paper".
    PLoS Comput Biol. 2025;21:e1013673.
    PubMed     Abstract available


  28. REYNOLDS J, Pan C
    Benchmarking interpretability of deep learning for predictive genomics: Recall, precision, and variability of feature attribution.
    PLoS Comput Biol. 2025;21:e1013784.
    PubMed     Abstract available


  29. DODERO-ROJAS E, Mendieta A, Fehlis Y, Mayala N, et al
    Epigenetics is all you need: A transformer to decode chromatin structural compartments from the epigenome.
    PLoS Comput Biol. 2025;21:e1012326.
    PubMed     Abstract available


  30. COLEMAN S, Breckels L, Waller RF, Lilley KS, et al
    Semi-supervised Bayesian integration of multiple spatial proteomics datasets.
    PLoS Comput Biol. 2025;21:e1013799.
    PubMed     Abstract available


  31. CHEN D, Storey JD
    Coancestry superposed on admixed populations yields measures of relatedness at individual-level resolution.
    PLoS Comput Biol. 2025;21:e1013848.
    PubMed     Abstract available


    November 2025
  32. YIN Y, Zhuang L, Wang Y, Shi Y, et al
    Branch-specific gene discovery in cell differentiation using multi-omics graph attention.
    PLoS Comput Biol. 2025;21:e1013664.
    PubMed     Abstract available


    October 2025
  33. MI Y, Cahill B, Yallapragada VVB, Rotem R, et al
    AI-driven discovery of novel extracellular matrix biomarkers in pelvic organ prolapse.
    PLoS Comput Biol. 2025;21:e1013483.
    PubMed     Abstract available


  34. LIANG X, Xiao S, Ba L, Feng Y, et al
    Spatial domain identification method based on multi-view graph convolutional network and contrastive learning.
    PLoS Comput Biol. 2025;21:e1013369.
    PubMed     Abstract available


    September 2025
  35. MULLER NF, Bouckaert RR, Wu CH, Bedford T, et al
    MASCOT-Skyline integrates population and migration dynamics to enhance phylogeographic reconstructions.
    PLoS Comput Biol. 2025;21:e1013421.
    PubMed     Abstract available


  36. XIAO T, Liu Y, Hu K, Guo K, et al
    Drug-induced liver injury prediction based on graph convolutional networks and toxicogenomics.
    PLoS Comput Biol. 2025;21:e1013423.
    PubMed     Abstract available


  37. ZAK J, Newman I, Montiel Garcia DJ, Parisi D, et al
    Catalyzing computational biology research at an academic institute through an interest network.
    PLoS Comput Biol. 2025;21:e1013453.
    PubMed     Abstract available


  38. YANG J, Grant GR, Brooks TG
    Generating correlated data for omics simulation.
    PLoS Comput Biol. 2025;21:e1013392.
    PubMed     Abstract available


  39. TRUONG L, Truong T, Nguyen H
    OmnibusX: A unified platform for accessible multi-omics analysis.
    PLoS Comput Biol. 2025;21:e1013480.
    PubMed     Abstract available


  40. WANG X, Guan Y, Gao W, Lai X, et al
    MRDtarget: A heuristic Gaussian approach for optimizing targeted capture regions to enhance Minimal Residual Disease detection.
    PLoS Comput Biol. 2025;21:e1013443.
    PubMed     Abstract available


  41. MA Z, Chen R, Feng Z
    Exploration of potential novel drug targets for rheumatoid arthritis by plasma proteome screening.
    PLoS Comput Biol. 2025;21:e1013333.
    PubMed     Abstract available


  42. GAO C, Yang C, Zhang L
    A graph neural network-based spatial multi-omics data integration method for deciphering spatial domains.
    PLoS Comput Biol. 2025;21:e1013546.
    PubMed     Abstract available


  43. YUAN R, Rong Z, Hu H, Liu T, et al
    Harmony-based data integration for distributed single-cell multi-omics data.
    PLoS Comput Biol. 2025;21:e1013526.
    PubMed     Abstract available


  44. LUCAS A, Schaffer DE, Wickramasinghe J, Auslander N, et al
    kMermaid: Ultrafast metagenomic read assignment to protein clusters by hashing of amino acid k-mer frequencies.
    PLoS Comput Biol. 2025;21:e1013470.
    PubMed     Abstract available


    August 2025
  45. ROBERTSON J, Consul S, Vikalo H
    NextVir: Enabling classification of tumor-causing viruses with genomic foundation models.
    PLoS Comput Biol. 2025;21:e1013360.
    PubMed     Abstract available


  46. YUAN H, Liu M, Qiu Y, Ching WK, et al
    PLNMFG: Pseudo-label guided non-negative matrix factorization model with graph constraint for single-cell multi-omics data clustering.
    PLoS Comput Biol. 2025;21:e1013375.
    PubMed     Abstract available


    July 2025
  47. DONG X, Jiao D, Xue H, Fan S, et al
    APAV: An advanced pangenome analysis and visualization toolkit.
    PLoS Comput Biol. 2025;21:e1013288.
    PubMed     Abstract available


    June 2025
  48. WADDEL H, Koelle K, Lau MSY
    ScITree: Scalable Bayesian inference of transmission tree from epidemiological and genomic data.
    PLoS Comput Biol. 2025;21:e1012657.
    PubMed     Abstract available


    May 2025
  49. GOLDMAN M, Zhao C, Pollard KS
    Improved detection of microbiome-disease associations via population structure-aware generalized linear mixed effects models (microSLAM).
    PLoS Comput Biol. 2025;21:e1012277.
    PubMed     Abstract available


    April 2025
  50. SHEN C, Wedell E, Pop M, Warnow T, et al
    TIPP3 and TIPP3-fast: Improved abundance profiling in metagenomics.
    PLoS Comput Biol. 2025;21:e1012593.
    PubMed     Abstract available


  51. LIU W, Pratte KA, Castaldi PJ, Hersh C, et al
    A generalized higher-order correlation analysis framework for multi-omics network inference.
    PLoS Comput Biol. 2025;21:e1011842.
    PubMed     Abstract available


  52. ROBERTS I, Everitt RG, Koskela J, Didelot X, et al
    Bayesian Inference of Pathogen Phylogeography using the Structured Coalescent Model.
    PLoS Comput Biol. 2025;21:e1012995.
    PubMed     Abstract available


  53. NOURBAKHSH M, Zheng Y, Noor H, Chen H, et al
    Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight.
    PLoS Comput Biol. 2025;21:e1012999.
    PubMed     Abstract available


    March 2025
  54. RYAN B, Marioni R, Simpson TI
    An integrative network approach for longitudinal stratification in Parkinson's disease.
    PLoS Comput Biol. 2025;21:e1012857.
    PubMed     Abstract available


  55. HAIMAN ZB, Key A, D'Alessandro A, Palsson BO, et al
    RBC-GEM: A genome-scale metabolic model for systems biology of the human red blood cell.
    PLoS Comput Biol. 2025;21:e1012109.
    PubMed     Abstract available


  56. WU Y, Chen M, Qin Y
    Anticancer drug response prediction integrating multi-omics pathway-based difference features and multiple deep learning techniques.
    PLoS Comput Biol. 2025;21:e1012905.
    PubMed     Abstract available


    February 2025
  57. KHODASEVICH D, Holland N, van der Laan L, Cardenas A, et al
    A SuperLearner-based pipeline for the development of DNA methylation-derived predictors of phenotypic traits.
    PLoS Comput Biol. 2025;21:e1012768.
    PubMed     Abstract available


  58. MIAO R, Yu HY, Zhong BJ, Sun HX, et al
    AWGE-ESPCA: An edge sparse PCA model based on adaptive noise elimination regularization and weighted gene network for Hermetia illucens genomic data analysis.
    PLoS Comput Biol. 2025;21:e1012773.
    PubMed     Abstract available


    January 2025
  59. PAN L, Gao Q, Wei K, Yu Y, et al
    A robust transfer learning approach for high-dimensional linear regression to support integration of multi-source gene expression data.
    PLoS Comput Biol. 2025;21:e1012739.
    PubMed     Abstract available


  60. DAOUD A, Ben-Hur A
    The role of chromatin state in intron retention: A case study in leveraging large scale deep learning models.
    PLoS Comput Biol. 2025;21:e1012755.
    PubMed     Abstract available


  61. FANG M, Gorin G, Pachter L
    Trajectory inference from single-cell genomics data with a process time model.
    PLoS Comput Biol. 2025;21:e1012752.
    PubMed     Abstract available


  62. GORSTEIN E, Aghdam R, Solis-Lemus C
    HighDimMixedModels.jl: Robust high-dimensional mixed-effects models across omics data.
    PLoS Comput Biol. 2025;21:e1012143.
    PubMed     Abstract available


    December 2024
  63. LAN W, Ling T, Chen Q, Zheng R, et al
    scMoMtF: An interpretable multitask learning framework for single-cell multi-omics data analysis.
    PLoS Comput Biol. 2024;20:e1012679.
    PubMed     Abstract available


  64. ESCRIBA-MONTAGUT X, Marcon Y, Anguita-Ruiz A, Avraam D, et al
    Federated privacy-protected meta- and mega-omics data analysis in multi-center studies with a fully open-source analytic platform.
    PLoS Comput Biol. 2024;20:e1012626.
    PubMed     Abstract available


  65. CICCOLELLA S, Cozzi D, Della Vedova G, Kuria SN, et al
    Differential quantification of alternative splicing events on spliced pangenome graphs.
    PLoS Comput Biol. 2024;20:e1012665.
    PubMed     Abstract available


  66. ABHARI N, Colijn C, Mooers A, Tupper P, et al
    Measuring genetic diversity across populations.
    PLoS Comput Biol. 2024;20:e1012651.
    PubMed     Abstract available


  67. ZUNIGA NR, Earls NE, Denos AEA, Elison JM, et al
    Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain.
    PLoS Comput Biol. 2024;20:e1012407.
    PubMed     Abstract available


  68. ORCALES F, Moctezuma Tan L, Johnson-Hagler M, Suntay JM, et al
    Using genomic data and machine learning to predict antibiotic resistance: A tutorial paper.
    PLoS Comput Biol. 2024;20:e1012579.
    PubMed     Abstract available


  69. BU Y, Liang J, Li Z, Wang J, et al
    Cancer molecular subtyping using limited multi-omics data with missingness.
    PLoS Comput Biol. 2024;20:e1012710.
    PubMed     Abstract available


    November 2024
  70. LI S, Gulisija D, Carja O
    The evolutionary cost of homophily: Social stratification facilitates stable variant coexistence and increased rates of evolution in host-associated pathogens.
    PLoS Comput Biol. 2024;20:e1012619.
    PubMed     Abstract available


    October 2024
  71. CHEN L, Huang ZH, Sun Y, Domaratzki M, et al
    Conditional probabilistic diffusion model driven synthetic radiogenomic applications in breast cancer.
    PLoS Comput Biol. 2024;20:e1012490.
    PubMed     Abstract available


  72. ROCHA U, Kasmanas JC, Toscan R, Sanches DS, et al
    Simulation of 69 microbial communities indicates sequencing depth and false positives are major drivers of bias in prokaryotic metagenome-assembled genome recovery.
    PLoS Comput Biol. 2024;20:e1012530.
    PubMed     Abstract available


  73. SILVA GAA, Harder AM, Kirksey KB, Mathur S, et al
    Detectability of runs of homozygosity is influenced by analysis parameters and population-specific demographic history.
    PLoS Comput Biol. 2024;20:e1012566.
    PubMed     Abstract available


    September 2024
  74. PLAISIER SB, Alarid DO, Denning JA, Brownell SE, et al
    Design and implementation of an asynchronous online course-based undergraduate research experience (CURE) in computational genomics.
    PLoS Comput Biol. 2024;20:e1012384.
    PubMed     Abstract available


  75. ABBARA A, Pagani L, Garcia-Pareja C, Bitbol AF, et al
    Mutant fate in spatially structured populations on graphs: Connecting models to experiments.
    PLoS Comput Biol. 2024;20:e1012424.
    PubMed     Abstract available


  76. LE SUEUR C, Rattray M, Savitski M
    GPMelt: A hierarchical Gaussian process framework to explore the dark meltome of thermal proteome profiling experiments.
    PLoS Comput Biol. 2024;20:e1011632.
    PubMed     Abstract available


  77. AMARAL AS, Devos DP
    The neglected giants: Uncovering the prevalence and functional groups of huge proteins in proteomes.
    PLoS Comput Biol. 2024;20:e1012459.
    PubMed     Abstract available


    August 2024
  78. NEY A, Nene NR, Sedlak E, Acedo P, et al
    Identification of a serum proteomic biomarker panel using diagnosis specific ensemble learning and symptoms for early pancreatic cancer detection.
    PLoS Comput Biol. 2024;20:e1012408.
    PubMed     Abstract available


  79. RINTALA TJ, Fortino V
    COPS: A novel platform for multi-omic disease subtype discovery via robust multi-objective evaluation of clustering algorithms.
    PLoS Comput Biol. 2024;20:e1012275.
    PubMed     Abstract available


  80. SHI P, Han J, Zhang Y, Li G, et al
    IMI-driver: Integrating multi-level gene networks and multi-omics for cancer driver gene identification.
    PLoS Comput Biol. 2024;20:e1012389.
    PubMed     Abstract available


    July 2024
  81. CHEN AA, Clark K, Dewey BE, DuVal A, et al
    PARE: A framework for removal of confounding effects from any distance-based dimension reduction method.
    PLoS Comput Biol. 2024;20:e1012241.
    PubMed     Abstract available


    June 2024
  82. BERGMAN S, Tuller T
    Strong association between genomic 3D structure and CRISPR cleavage efficiency.
    PLoS Comput Biol. 2024;20:e1012214.
    PubMed     Abstract available


    May 2024
  83. ABDENNUR N, Abraham S, Fudenberg G, Flyamer IM, et al
    Cooltools: Enabling high-resolution Hi-C analysis in Python.
    PLoS Comput Biol. 2024;20:e1012067.
    PubMed     Abstract available


  84. GORMAN ED, Lladser ME
    Interpretable metric learning in comparative metagenomics: The adaptive Haar-like distance.
    PLoS Comput Biol. 2024;20:e1011543.
    PubMed     Abstract available


  85. CASCARINA SM, Ross ED
    Identification of Low-Complexity Domains by Compositional Signatures Reveals Class-Specific Frequencies and Functions Across the Domains of Life.
    PLoS Comput Biol. 2024;20:e1011372.
    PubMed     Abstract available


  86. WANG M, Yan X, Dong Y, Li X, et al
    Machine learning and multi-omics data reveal driver gene-based molecular subtypes in hepatocellular carcinoma for precision treatment.
    PLoS Comput Biol. 2024;20:e1012113.
    PubMed     Abstract available


    April 2024
  87. GIUDICE L, Mohamed A, Malm T
    StellarPath: Hierarchical-vertical multi-omics classifier synergizes stable markers and interpretable similarity networks for patient profiling.
    PLoS Comput Biol. 2024;20:e1012022.
    PubMed     Abstract available


    March 2024
  88. MARTIN NS, Camargo CQ, Louis AA
    Bias in the arrival of variation can dominate over natural selection in Richard Dawkins's biomorphs.
    PLoS Comput Biol. 2024;20:e1011893.
    PubMed     Abstract available


  89. WIEDER C, Cooke J, Frainay C, Poupin N, et al
    PathIntegrate: Multivariate modelling approaches for pathway-based multi-omics data integration.
    PLoS Comput Biol. 2024;20:e1011814.
    PubMed     Abstract available


    February 2024
  90. LIU X, Gillis N, Jiang C, McCofie A, et al
    An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level.
    PLoS Comput Biol. 2024;20:e1011873.
    PubMed     Abstract available


  91. DALL'OLIO D, Strang E, Turki AT, Tettero JM, et al
    Covering Hierarchical Dirichlet Mixture Models on binary data to enhance genomic stratifications in onco-hematology.
    PLoS Comput Biol. 2024;20:e1011299.
    PubMed     Abstract available


    January 2024
  92. ROBLES J, Prakash A, Vizcaino JA, Casal JI, et al
    Integrated meta-analysis of colorectal cancer public proteomic datasets for biomarker discovery and validation.
    PLoS Comput Biol. 2024;20:e1011828.
    PubMed     Abstract available


  93. MUKHERJEE A, Chang YF, Huang Y, Benites NC, et al
    Plasticity of growth laws tunes resource allocation strategies in bacteria.
    PLoS Comput Biol. 2024;20:e1011735.
    PubMed     Abstract available


  94. PFLUG FG, Bhat D, Pigolotti S
    Genome replication in asynchronously growing microbial populations.
    PLoS Comput Biol. 2024;20:e1011753.
    PubMed     Abstract available


  95. LOUARN M, Collet G, Barre E, Fest T, et al
    Regulus infers signed regulatory relations from few samples' information using discretization and likelihood constraints.
    PLoS Comput Biol. 2024;20:e1011816.
    PubMed     Abstract available


  96. MANCUSO CA, Johnson KA, Liu R, Krishnan A, et al
    Joint representation of molecular networks from multiple species improves gene classification.
    PLoS Comput Biol. 2024;20:e1011773.
    PubMed     Abstract available


  97. EL BOUHADDANI S, Hollerhage M, Uh HW, Moebius C, et al
    Statistical integration of multi-omics and drug screening data from cell lines.
    PLoS Comput Biol. 2024;20:e1011809.
    PubMed     Abstract available


    December 2023
  98. SINGH A, Chakrabarti S
    Diffusion controls local versus dispersed inheritance of histones during replication and shapes epigenomic architecture.
    PLoS Comput Biol. 2023;19:e1011725.
    PubMed     Abstract available


    November 2023
  99. VASILEIOU D, Karapiperis C, Baltsavia I, Chasapi A, et al
    CGG toolkit: Software components for computational genomics.
    PLoS Comput Biol. 2023;19:e1011498.
    PubMed     Abstract available


  100. SCHMIDT H, Sashittal P, Raphael BJ
    A zero-agnostic model for copy number evolution in cancer.
    PLoS Comput Biol. 2023;19:e1011590.
    PubMed     Abstract available


  101. KIPEN J, Jalden J
    Beam search decoder for enhancing sequence decoding speed in single-molecule peptide sequencing data.
    PLoS Comput Biol. 2023;19:e1011345.
    PubMed     Abstract available


  102. HEUPINK TH, Verboven L, Sharma A, Rennie V, et al
    The MAGMA pipeline for comprehensive genomic analyses of clinical Mycobacterium tuberculosis samples.
    PLoS Comput Biol. 2023;19:e1011648.
    PubMed     Abstract available


  103. BRUNNER JD, Gallegos-Graves LA, Kroeger ME
    Inferring microbial interactions with their environment from genomic and metagenomic data.
    PLoS Comput Biol. 2023;19:e1011661.
    PubMed     Abstract available


  104. CECIL RM, Sugden LA
    On convolutional neural networks for selection inference: Revealing the effect of preprocessing on model learning and the capacity to discover novel patterns.
    PLoS Comput Biol. 2023;19:e1010979.
    PubMed     Abstract available


    October 2023
  105. GAO Y, Sun F
    Batch normalization followed by merging is powerful for phenotype prediction integrating multiple heterogeneous studies.
    PLoS Comput Biol. 2023;19:e1010608.
    PubMed     Abstract available


  106. KOSINSKI JG, Zywicki M
    AGouTI-Flexible Annotation of Genomic and Transcriptomic Intervals.
    PLoS Comput Biol. 2023;19:e1011527.
    PubMed     Abstract available


  107. YELMEN B, Decelle A, Boulos LL, Szatkownik A, et al
    Deep convolutional and conditional neural networks for large-scale genomic data generation.
    PLoS Comput Biol. 2023;19:e1011584.
    PubMed     Abstract available


    September 2023
  108. ZHANG Y, Zhou R, Liu L, Chen L, et al
    Trackplot: A flexible toolkit for combinatorial analysis of genomic data.
    PLoS Comput Biol. 2023;19:e1011477.
    PubMed     Abstract available


  109. HUANG Z, Cui X, Xia Y, Zhao K, et al
    Pathfinder: Protein folding pathway prediction based on conformational sampling.
    PLoS Comput Biol. 2023;19:e1011438.
    PubMed     Abstract available


  110. TCHOUNKE B, Sanchez L, Bell JM, Cros D, et al
    Mate selection: A useful approach to maximize genetic gain and control inbreeding in genomic and conventional oil palm (Elaeis guineensis Jacq.) hybrid breeding.
    PLoS Comput Biol. 2023;19:e1010290.
    PubMed     Abstract available


  111. BOUTRY S, Helaers R, Lenaerts T, Vikkula M, et al
    Excalibur: A new ensemble method based on an optimal combination of aggregation tests for rare-variant association testing for sequencing data.
    PLoS Comput Biol. 2023;19:e1011488.
    PubMed     Abstract available


    August 2023
  112. CHARI T, Pachter L
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    VarSCAT: A computational tool for sequence context annotations of genomic variants.
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    A mutation-level covariate model for mutational signatures.
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    ResMiCo: Increasing the quality of metagenome-assembled genomes with deep learning.
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    adaPop: Bayesian inference of dependent population dynamics in coalescent models.
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    JASPER: A fast genome polishing tool that improves accuracy of genome assemblies.
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    G4mismatch: Deep neural networks to predict G-quadruplex propensity based on G4-seq data.
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    Host heterogeneity and epistasis explain punctuated evolution of SARS-CoV-2.
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    Kinome inhibition states and multiomics data enable prediction of cell viability in diverse cancer types.
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