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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 29 articles:
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Single Articles


    March 2026
  1. JIANG J, Zuo M, Zhao K, Ling Z, et al
    mtDNA leakage promotes neuron-glia crosstalk to induce epilepsy by cGAS-STING-driven neuroinflammation and serine metabolic reprogramming.
    Proc Natl Acad Sci U S A. 2026;123:e2522313123.
    PubMed     Abstract available


    February 2026
  2. LI M, Zhu Z, Li D, Wang J, et al
    CDKL5 modulates the plasticity of excitatory synapses via liquid-liquid phase separation.
    Proc Natl Acad Sci U S A. 2026;123:e2511123123.
    PubMed     Abstract available


    December 2025
  3. JIANG X, Cai Z, Gonsisko C, Worrell GA, et al
    Mapping epileptogenic brain using a unified spatial-temporal-spectral source imaging framework.
    Proc Natl Acad Sci U S A. 2025;122:e2510015122.
    PubMed     Abstract available


    August 2025
  4. JANG SS, Agranonik N, Huguenard JR
    Actions of the antiseizure drug carbamazepine in the thalamic reticular nucleus: Potential mechanism of aggravating absence seizures.
    Proc Natl Acad Sci U S A. 2025;122:e2500644122.
    PubMed     Abstract available


    July 2025
  5. BIZZOTTO S, Talukdar M, Stronge EA, Ramirez RB, et al
    Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs.
    Proc Natl Acad Sci U S A. 2025;122:e2509622122.
    PubMed     Abstract available


  6. STASENKO A, Kaestner E, Schadler AJ, Reyes A, et al
    Dynamic neuroplasticity of language networks: The intersection of bilingualism and epilepsy.
    Proc Natl Acad Sci U S A. 2025;122:e2422742122.
    PubMed     Abstract available


    June 2025
  7. TABIKH M, Quetu T, Maillard L, Colnat-Coulbois S, et al
    Transcranial direct current stimulation neuromodulates intracranial cognitive evoked activity in humans.
    Proc Natl Acad Sci U S A. 2025;122:e2416541122.
    PubMed     Abstract available


    April 2025
  8. MULLER PM, Miron G, Holtkamp M, Meisel C, et al
    Critical dynamics predicts cognitive performance and provides a common framework for heterogeneous mechanisms impacting cognition.
    Proc Natl Acad Sci U S A. 2025;122:e2417117122.
    PubMed     Abstract available


  9. HYDER SK, Lazarini-Lopes W, Toib J, Williams G, et al
    Optogenetic stimulation of the dorsal striatum bidirectionally controls seizures.
    Proc Natl Acad Sci U S A. 2025;122:e2419178122.
    PubMed     Abstract available


    February 2025
  10. MAHER C, Tortolero L, Jun S, Cummins DD, et al
    Intracranial substrates of meditation-induced neuromodulation in the amygdala and hippocampus.
    Proc Natl Acad Sci U S A. 2025;122:e2409423122.
    PubMed     Abstract available


    December 2024
  11. RAMIREZ JG, Vanhoyland M, Ratan Murty NA, Decramer T, et al
    Intracortical recordings reveal the neuronal selectivity for bodies and body parts in the human visual cortex.
    Proc Natl Acad Sci U S A. 2024;121:e2408871121.
    PubMed     Abstract available


  12. KAN ASH, Kusay AS, Mohammadi NA, Lin SXN, et al
    Understanding paralogous epilepsy-associated GABA(A) receptor variants: Clinical implications, mechanisms, and potential pitfalls.
    Proc Natl Acad Sci U S A. 2024;121:e2413011121.
    PubMed     Abstract available


  13. CHOI JM, Acharya R, Cha HL, Lee KW, et al
    CB1R activates the epilepsy-associated protein Go to regulate neurotransmitter release and synaptic plasticity in the cerebellum.
    Proc Natl Acad Sci U S A. 2024;121:e2409773121.
    PubMed     Abstract available


  14. PATEL A, Pauzuolyte V, Ingham NJ, Leong YC, et al
    Rescue of cochlear vascular pathology prevents sensory hair cell loss in Norrie disease.
    Proc Natl Acad Sci U S A. 2024;121:e2322124121.
    PubMed     Abstract available


    October 2024
  15. WANG W, Williams DJ, Teoh JJ, Soundararajan D, et al
    Impaired axon initial segment structure and function in a model of ARHGEF9 developmental and epileptic encephalopathy.
    Proc Natl Acad Sci U S A. 2024;121:e2400709121.
    PubMed     Abstract available


    July 2024

  16. Correction for Veno et al., A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy.
    Proc Natl Acad Sci U S A. 2024;121:e2411972121.
    PubMed    


  17. DONG P, Bakhurin K, Li Y, Mikati MA, et al
    Attenuating midline thalamus bursting to mitigate absence epilepsy.
    Proc Natl Acad Sci U S A. 2024;121:e2403763121.
    PubMed     Abstract available


  18. ROBERT S, Granovetter MC, Patterson C, Behrmann M, et al
    Hemispheric functional organization, as revealed by naturalistic neuroimaging, in pediatric epilepsy patients with cortical resections.
    Proc Natl Acad Sci U S A. 2024;121:e2317458121.
    PubMed     Abstract available


    June 2024
  19. CAPITANO F, Kuchenbuch M, Lavigne J, Chaptoukaev H, et al
    Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to low-voltage-fast onset seizures in Dravet syndrome.
    Proc Natl Acad Sci U S A. 2024;121:e2316364121.
    PubMed     Abstract available


    May 2024
  20. PARK J, Lee E, Kim CH, Ohk J, et al
    Mosaicism-independent mechanisms contribute to Pcdh19-related epilepsy and repetitive behaviors in Xenopus.
    Proc Natl Acad Sci U S A. 2024;121:e2321388121.
    PubMed     Abstract available


    April 2024
  21. XU N, Cao R, Chen SY, Gou XZ, et al
    Structural and functional reorganization of inhibitory synapses by activity-dependent cleavage of neuroligin-2.
    Proc Natl Acad Sci U S A. 2024;121:e2314541121.
    PubMed     Abstract available


  22. COSTANZA M, Ciotti A, Consonni A, Cipelletti B, et al
    CNS autoimmune response in the MAM/pilocarpine rat model of epileptogenic cortical malformation.
    Proc Natl Acad Sci U S A. 2024;121:e2319607121.
    PubMed     Abstract available


    February 2024
  23. ZITO A, Lee JT
    Variable expression of MECP2, CDKL5, and FMR1 in the human brain: Implications for gene restorative therapies.
    Proc Natl Acad Sci U S A. 2024;121:e2312757121.
    PubMed     Abstract available


  24. YANG YC, Wang GH, Chou P, Hsueh SW, et al
    Dynamic electrical synapses rewire brain networks for persistent oscillations and epileptogenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2313042121.
    PubMed     Abstract available


    January 2024
  25. CLATOT J, Currin CB, Liang Q, Pipatpolkai T, et al
    A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction.
    Proc Natl Acad Sci U S A. 2024;121:e2307776121.
    PubMed     Abstract available


    December 2023
  26. GULFO MC, Lebowitz JJ, Ramos C, Hwang DW, et al
    Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function.
    Proc Natl Acad Sci U S A. 2023;120:e2307509120.
    PubMed     Abstract available


    November 2023
  27. ZHONG X, Moresco JJ, Keller K, Lazaro DR, et al
    Essential requirement for IER3IP1 in B cell development.
    Proc Natl Acad Sci U S A. 2023;120:e2312810120.
    PubMed     Abstract available


    September 2023
  28. MOHAMED MS, Klann E
    Autism- and epilepsy-associated EEF1A2 mutations lead to translational dysfunction and altered actin bundling.
    Proc Natl Acad Sci U S A. 2023;120:e2307704120.
    PubMed     Abstract available


  29. ARAKI Y, Gerber EE, Rajkovich KE, Hong I, et al
    Mouse models of SYNGAP1-related intellectual disability.
    Proc Natl Acad Sci U S A. 2023;120:e2308891120.
    PubMed     Abstract available


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