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Articles published in Antimicrob Agents Chemother

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    July 2021
  1. KAWAI A, Suzuki M, Tsukamoto K, Minato Y, et al
    Functional and Structural Characterization of Acquired Pan-Aminoglycoside Resistance 16S rRNA Methyltransferase NpmB1.
    Antimicrob Agents Chemother. 2021 Jul 26:AAC0100921. doi: 10.1128/AAC.01009.
    PubMed     Abstract available


  2. WANG J, Ma W, Fang Y, Liang H, et al
    Core oligosaccharide portion of lipopolysaccharide plays important roles on multiple antibiotic resistance in Escherichia coli.
    Antimicrob Agents Chemother. 2021 Jul 26:AAC0034121. doi: 10.1128/AAC.00341.
    PubMed     Abstract available


  3. GILL CM, Brink A, Chu CY, Coetzee J, et al
    The Phenotypic/Genotypic Profile of OXA-10-like harboring, Carbapenem-Resistant Pseudomonas aeruginosa: Using Validated Pharmacokinetic/Pharmacodynamic in vivo Models to Further Evaluate Enzyme Functionality and Clinical Implications.
    Antimicrob Agents Chemother. 2021 Jul 26:AAC0127421. doi: 10.1128/AAC.01274.
    PubMed     Abstract available


  4. MITCHEV N, Singh R, Allam M, Kwenda S, et al
    Antimicrobial resistance mechanisms, MLST and NG-STAR sequence types of diverse Neisseria gonorrhoeae isolates in KwaZulu-Natal, South Africa.
    Antimicrob Agents Chemother. 2021 Jul 19:AAC0075921. doi: 10.1128/AAC.00759.
    PubMed     Abstract available


  5. LE C, Pimentel C, Tuttobene MR, Subils T, et al
    Interplay between meropenem and human serum albumin on expression of carbapenem resistance genes and natural competence in Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2021 Jul 19:AAC0101921. doi: 10.1128/AAC.01019.
    PubMed     Abstract available


  6. WESTGEEST AC, Schippers EF, Delfos NM, Ellerbroek LJ, et al
    Complicated carriage with methicillin-resistant Staphylococcus aureus (MRSA): evaluation of the effectiveness of decolonization regimens advised in the Dutch national guideline.
    Antimicrob Agents Chemother. 2021 Jul 6:AAC0025721. doi: 10.1128/AAC.00257.
    PubMed     Abstract available


  7. TRAUNER A, Banaei-Esfahani A, Gygli SM, Warmer P, et al
    Expression dysregulation as a mediator of fitness costs in antibiotic resistance.
    Antimicrob Agents Chemother. 2021 Jul 6:AAC0050421. doi: 10.1128/AAC.00504.
    PubMed     Abstract available


  8. CHEN L, Han X, Li Y, Li M, et al
    Assessment of mortality-related risk factors and effective antimicrobial regimens for the treatment of bloodstream infections caused by carbapenem-resistant Enterobacterales.
    Antimicrob Agents Chemother. 2021 Jul 6:AAC0069821. doi: 10.1128/AAC.00698.
    PubMed     Abstract available


    June 2021
  9. SOMPRASONG N, Yi J, Hall CM, Webb JR, et al
    Conservation of resistance nodulation cell division efflux pump mediated antibiotic resistance in Burkholderia cepacia complex and Burkholderia pseudomallei complex species.
    Antimicrob Agents Chemother. 2021 Jun 28:AAC0092021. doi: 10.1128/AAC.00920.
    PubMed     Abstract available


  10. FERREIRA S, Silva AL, Tomas J, Mateus C, et al
    Characterization of AreABC, an RND-type efflux system involved in antimicrobial resistance of Aliarcobacter butzleri.
    Antimicrob Agents Chemother. 2021 Jun 21:AAC0072921. doi: 10.1128/AAC.00729.
    PubMed     Abstract available


  11. PLAUNT AJ, Rose SJ, Kang JY, Chen KJ, et al
    Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections.
    Antimicrob Agents Chemother. 2021;65:e0031621.
    PubMed     Abstract available


  12. KORNELSEN V, Kumar A
    Update on Multidrug Resistance Efflux Pumps in Acinetobacter spp.
    Antimicrob Agents Chemother. 2021;65:e0051421.
    PubMed     Abstract available


  13. ZARROUK K, Zhu X, Pham VD, Goyette N, et al
    Impact of Amino Acid Substitutions in Region II and Helix K of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Resistance to Foscarnet.
    Antimicrob Agents Chemother. 2021;65:e0039021.
    PubMed     Abstract available


  14. LIZZA BD, Betthauser KD, Ritchie DJ, Micek ST, et al
    New Perspectives on Antimicrobial Agents: Ceftolozane-Tazobactam.
    Antimicrob Agents Chemother. 2021;65:e0231820.
    PubMed     Abstract available


  15. GUTHRIDGE I, Smith S, Law M, Binotto E, et al
    The efficacy and safety of intravenous lincosamide therapy in methicillin-resistant Staphylococcus aureus bacteremia.
    Antimicrob Agents Chemother. 2021 Jun 14:AAC0034321. doi: 10.1128/AAC.00343.
    PubMed     Abstract available


  16. HUANG DB, Gaukel E, Kerzee N, Borroto-Esoda K, et al
    Efficacy of Anti-Staphylococcal Lysin, LSVT-1701, in Combination with Daptomycin in Experimental Left-Sided Infective Endocarditis Due to Methicillin-Resistant Staphylococcus aureus (MRSA).
    Antimicrob Agents Chemother. 2021 Jun 7:AAC0050821. doi: 10.1128/AAC.00508.
    PubMed     Abstract available


  17. LEW C, Mishra NN, Bayer AS, Rose WE, et al
    beta-lactam-induced cell envelope adaptations, not solely enhanced daptomycin binding, underlies daptomycin-beta-lactam synergy in methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2021 Jun 7:AAC0035621. doi: 10.1128/AAC.00356.
    PubMed     Abstract available


  18. GUO Q, Zhang Y, Fan J, Zhang H, et al
    MAB_2355c Confers Macrolide Resistance in Mycobacterium abscessus by Ribosome Protection.
    Antimicrob Agents Chemother. 2021 Jun 7:AAC0033021. doi: 10.1128/AAC.00330.
    PubMed     Abstract available


  19. ABOU FAYAD AG, Haraoui LP, Sleiman A, Jaafar M, et al
    Diversity of sequence types and impact of fitness cost among carbapenem-resistant Acinetobacter baumannii isolates from Tripoli, Libya.
    Antimicrob Agents Chemother. 2021 Jun 7:AAC0027721. doi: 10.1128/AAC.00277.
    PubMed     Abstract available


  20. WANG C, Yin M, Zhang X, Guo Q, et al
    Identification of qnrE3 and qnrE4, new transferable quinolone resistance qnrE family genes originating from Enterobacter mori and E. asburiae, respectively.
    Antimicrob Agents Chemother. 2021 Jun 7:AAC0045621. doi: 10.1128/AAC.00456.
    PubMed     Abstract available


  21. LUCASSEN K, Gerson S, Xanthopoulou K, Wille J, et al
    Comparison of the A. baumannii reference strains ATCC 17978 and ATCC 19606 in antimicrobial resistance mediated by the AdeABC efflux pump.
    Antimicrob Agents Chemother. 2021 Jun 7:AAC0057021. doi: 10.1128/AAC.00570.
    PubMed     Abstract available


  22. BHATNAGAR A, Boyd S, Sabour S, Bodnar J, et al
    Aztreonam-Avibactam Susceptibility Testing Program for Metallo-beta-lactamase-producing Enterobacterales in the Antibiotic Resistance Laboratory Network, March 2019-December 2020.
    Antimicrob Agents Chemother. 2021 Jun 1:AAC0048621. doi: 10.1128/AAC.00486.
    PubMed     Abstract available


    May 2021
  23. RUBIO AM, Kline EG, Jones CE, Chen L, et al
    In Vitro Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa following Treatment-Emergent Resistance to Ceftolozane-Tazobactam.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  24. SOLIMAN AM, Ramadan H, Zarad H, Sugawara Y, et al
    Coproduction of Tet(X7) Conferring High-Level Tigecycline Resistance, Fosfomycin FosA4, and Colistin Mcr-1.1 in Escherichia coli Strains from Chickens in Egypt.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  25. DESNOS-OLLIVIER M, Lortholary O, Bretagne S, Dromer F, et al
    Azole Susceptibility Profiles of More than 9,000 Clinical Yeast Isolates Belonging to 40 Common and Rare Species.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  26. MOIRANGTHEM R, Kumar K, Kaur R
    Two Functionally Redundant FK506-Binding Proteins Regulate Multidrug Resistance Gene Expression and Govern Azole Antifungal Resistance.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  27. CHEUNG CHP, Alorabi M, Hamilton F, Takebayashi Y, et al
    Trade-Offs Between Antibacterial Resistance and Fitness Cost in the Production of Metallo-beta-Lactamases by Enteric Bacteria Manifest as Sporadic Emergence of Carbapenem Resistance in a Clinical Setting.
    Antimicrob Agents Chemother. 2021 May 10. pii: AAC.02412.
    PubMed     Abstract available


  28. RUELENS P, de Visser JAGM
    Choice of beta-lactam resistance pathway depends critically on initial antibiotic concentration.
    Antimicrob Agents Chemother. 2021 May 10. pii: AAC.00471.
    PubMed     Abstract available


  29. MCGUIRE RJ, Yu SC, Payne PRO, Lai AM, et al
    A Pragmatic Machine Learning Model to Predict Carbapenem Resistance.
    Antimicrob Agents Chemother. 2021 May 10. pii: AAC.00063.
    PubMed     Abstract available


  30. KAZMIERCZAK KM, Karlowsky JA, de Jonge BLM, Stone GG, et al
    Epidemiology of Carbapenem Resistance Determinants Identified in Meropenem-nonsusceptible Enterobacterales collected as part of a Global Surveillance Program, 2012-2017.
    Antimicrob Agents Chemother. 2021 May 10. pii: AAC.02000.
    PubMed     Abstract available


  31. DARLOW CA, Docobo-Perez F, Farrington N, Johnson A, et al
    Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance.
    Antimicrob Agents Chemother. 2021 May 10. pii: AAC.00293.
    PubMed     Abstract available


  32. FREDERICKS LR, Lee MD, Eckert HR, Li S, et al
    Vaginal Isolates of Candida glabrata are Uniquely Susceptible to Ionophoric Killer Toxins Produced by Saccharomyces cerevisiae.
    Antimicrob Agents Chemother. 2021 May 10. pii: AAC.02450.
    PubMed     Abstract available


  33. JANICE J, Agyepong N, Owusu-Ofori A, Govinden U, et al
    Carbapenem-resistance determinants acquired through novel chromosomal integrations in XDR Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2021 May 3. pii: AAC.00289.
    PubMed     Abstract available


  34. LIANG T, Yang X, Li R, Yang E, et al
    Emergence of W272C Substitution in Hmg1 in a Triazole-Resistant Isolate of Aspergillus fumigatus from a Chinese Patient with Chronic Cavitary Pulmonary Aspergillosis.
    Antimicrob Agents Chemother. 2021 May 3. pii: AAC.00263.
    PubMed     Abstract available


    April 2021
  35. LEY SD, Pillay S, Streicher EM, van der Heijden YF, et al
    Melting the Eis: non-detection of kanamycin resistance markers by routine diagnostic tests and identification of new eis-promoter variants.
    Antimicrob Agents Chemother. 2021 Apr 26. pii: AAC.02502.
    PubMed     Abstract available


  36. KIM DH, Kim SY, Koh WJ, Jhun BW, et al
    In Vitro Activity of Oxazolidinone against Nontuberculous Mycobacteria, Including Macrolide-Resistant Clinical Isolates.
    Antimicrob Agents Chemother. 2021 Apr 26. pii: AAC.02306.
    PubMed     Abstract available


  37. SONNENKALB L, Strohe G, Dreyer V, Andres S, et al
    Microevolution of Mycobacterium tuberculosis hetero-resistance subpopulations in a patient receiving 27 years of tuberculosis treatment in Germany.
    Antimicrob Agents Chemother. 2021 Apr 26. pii: AAC.02520.
    PubMed     Abstract available


  38. CRANE JK, Alvarado CL, Sutton MD
    Role of the SOS Response in the Generation of Antibiotic Resistance In Vivo.
    Antimicrob Agents Chemother. 2021 Apr 19. pii: AAC.00013.
    PubMed     Abstract available


  39. REHMAN A, Jeukens J, Levesque RC, Lamont IL, et al
    Gene-gene interactions dictate ciprofloxacin resistance in Pseudomonas aeruginosa and facilitate prediction of resistance phenotype from genome sequence data.
    Antimicrob Agents Chemother. 2021 Apr 19. pii: AAC.02696.
    PubMed     Abstract available


  40. YAO D, Zhang G, Chen W, Chen J, et al
    Pyrogallol and Fluconazole Interact Synergistically In Vitro Against Candida glabrata Through an Efflux-Associated Mechanism.
    Antimicrob Agents Chemother. 2021 Apr 19. pii: AAC.00100.
    PubMed     Abstract available


  41. OKOLIEGBE IN, Hijazi K, Cooper K, Ironside C, et al
    Trends of antimicrobial resistance and combination susceptibility testing of cystic fibrosis multidrug-resistant Pseudomonas aeruginosa: A ten-year update.
    Antimicrob Agents Chemother. 2021 Apr 5. pii: AAC.02483.
    PubMed     Abstract available


  42. POULSEN JS, Madsen AM, White JK, Nielsen JL, et al
    Physiological responses of Aspergillus niger challenged with itraconazole.
    Antimicrob Agents Chemother. 2021 Apr 5. pii: AAC.02549.
    PubMed     Abstract available


    March 2021
  43. GIL-MARQUES ML, Jacoby GA, Hooper DC
    Analyzing possible native functions of the quinolone resistance gene qnr in Vibrio vulnificus.
    Antimicrob Agents Chemother. 2021 Mar 29. pii: AAC.00232.
    PubMed     Abstract available


  44. SICELOFF AT, Ohta N, Norman KN, Loneragan GH, et al
    Antimicrobial resistance hidden within multi-serovar Salmonella populations.
    Antimicrob Agents Chemother. 2021 Mar 29. pii: AAC.00048.
    PubMed     Abstract available


  45. STEWART AG, Price EP, Schabacker K, Birikmen M, et al
    Molecular epidemiology of third-generation cephalosporin-resistant Enterobacteriaceae in Southeast Queensland, Australia.
    Antimicrob Agents Chemother. 2021 Mar 29. pii: AAC.00130.
    PubMed     Abstract available


  46. MENGUAL-CHULIA B, Alonso-Cordero A, Cano L, Del Mar Mosquera M, et al
    Surveillance of Influenza A resistance to polymerase complex inhibitors by whole genome analysis, 2016-17, 2017-18 and 2018-19 Seasons, Eastern Spain.
    Antimicrob Agents Chemother. 2021 Mar 29. pii: AAC.02718.
    PubMed     Abstract available


  47. ORTIZ DE LA ROSA JM, Nordmann P, Poirel L
    Antioxidant molecules as a source of mitigation of antibiotic resistance genes dissemination.
    Antimicrob Agents Chemother. 2021 Mar 22. pii: AAC.02658.
    PubMed     Abstract available


  48. HIRVONEN VHA, Spencer J, van der Kamp MW
    Antimicrobial resistance conferred by OXA-48 beta-lactamases:towards a detailed mechanistic understanding.
    Antimicrob Agents Chemother. 2021 Mar 22. pii: AAC.00184.
    PubMed     Abstract available


  49. MASUKO A, Takata I, Fujita K, Okumura H, et al
    In Vitro and In Vivo Activities of TP0480066, a Novel Topoisomerase Inhibitor, against Neisseria gonorrhoeae.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  50. BOOT W, Schmid T, D'Este M, Guillaume O, et al
    A Hyaluronic Acid Hydrogel Loaded with Gentamicin and Vancomycin Successfully Eradicates Chronic Methicillin-Resistant Staphylococcus aureus Orthopedic Infection in a Sheep Model.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  51. NAKAMURA R, Oota M, Matsumoto S, Sato T, et al
    In Vitro Activity and In Vivo Efficacy of Cefiderocol against Stenotrophomonas maltophilia.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  52. MIRA PM, Ostman B, Guzman-Cole C, Sindi S, et al
    Adaptive Processes Change as Multiple Functions Evolve.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  53. DIAZ-GARCIA J, Mesquida A, Sanchez-Carrillo C, Reigadas E, et al
    Monitoring the Epidemiology and Antifungal Resistance of Yeasts Causing Fungemia in a Tertiary Care Hospital in Madrid, Spain: Any Relevant Changes in the Last 13 Years?
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  54. CAMP J, Schuster S, Vavra M, Schweigger T, et al
    Limited Multidrug Resistance Efflux Pump Overexpression among Multidrug-Resistant Escherichia coli Strains of ST131.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  55. CHENG J, Yan J, Reyna Z, Slarve M, et al
    Synergistic Rifabutin and Colistin Reduce Emergence of Resistance When Treating Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  56. KARAU MJ, Schmidt-Malan SM, Mandrekar J, Lehoux D, et al
    Activity of Lysin CF-296 Alone and in Addition to Daptomycin in a Rat Model of Experimental Methicillin-Resistant Staphylococcus aureus Osteomyelitis.
    Antimicrob Agents Chemother. 2021 Mar 15. pii: AAC.00117.
    PubMed     Abstract available


  57. MODLIN SJ, Marbach T, Werngren J, Mansjo M, et al
    Atypical Genetic Basis of Pyrazinamide Resistance in Mono-resistant Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2021 Mar 15. pii: AAC.01916.
    PubMed     Abstract available


  58. ARDIZZONI E, Ariza E, Mulengwa D, Mpala Q, et al
    Thin layer agar-based direct phenotypic drug-susceptibility testing on sputum in Eswatini rapidly detects Mycobacterium tuberculosis growth and rifampicin resistance, otherwise missed by WHO endorsed diagnostic tests.
    Antimicrob Agents Chemother. 2021 Mar 15. pii: AAC.02263.
    PubMed     Abstract available


  59. WEI Y, Sluis-Cremer N
    Mutations in the HIV-1 3'-Polypurine Tract and Integrase Strand-Transfer Inhibitor Resistance.
    Antimicrob Agents Chemother. 2021 Mar 15. pii: AAC.02432.
    PubMed     Abstract available


  60. CHO HK, Karau MJ, Greenwood-Quaintance KE, Hansford KA, et al
    In Vitro Activity of Vancapticin MCC5145 against Methicillin-Resistant Staphylococcus aureus from Periprosthetic Joint Infection.
    Antimicrob Agents Chemother. 2021 Mar 8. pii: AAC.02443.
    PubMed     Abstract available


  61. MOHD SAZLLY LIM S, Heffernan AJ, Roberts JA, Sime FB, et al
    Semi-mechanistic PK/PD modelling of fosfomycin and sulbactam combination against carbapenem-resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2021 Mar 8. pii: AAC.02472.
    PubMed     Abstract available


  62. ERSOY SC, Chambers HF, Proctor RA, Rosato AE, et al
    Impact of Bicarbonate on PBP2a Production, Maturation, and Functionality in Methicillin-Resistant Staphylococcus aureus (MRSA).
    Antimicrob Agents Chemother. 2021 Mar 1. pii: AAC.02621.
    PubMed     Abstract available


    February 2021
  63. ATTERBY C, Nykvist M, Lustig U, Andersson DI, et al
    Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  64. FANG Y, Kirsch JR, Li L, Brooks SA, et al
    Deimmunized Lysostaphin Synergizes with Small-Molecule Chemotherapies and Resensitizes Methicillin-Resistant Staphylococcus aureus to beta-Lactam Antibiotics.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  65. WANG G, Brunel JM, Bolla JM, Van Bambeke F, et al
    The Polyaminoisoprenyl Potentiator NV716 Revives Old Disused Antibiotics against Intracellular Forms of Infection by Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  66. LI Y, Li Y, Xiu L, Zeng Y, et al
    Typing of Neisseria Gonorrhoeae isolates in Shenzhen, China from 2014-2018 reveals the shift of genotypes associated with antimicrobial resistance.
    Antimicrob Agents Chemother. 2021 Feb 16. pii: AAC.02311.
    PubMed     Abstract available


  67. FEN SHY, Tandhavanant S, Phunpang R, Ekchariyawat P, et al
    Antibiotic susceptibility of clinical Burkholderia pseudomallei isolates in northeast Thailand during 2015-2018 and the genomic characterization of beta-lactam-resistant isolates.
    Antimicrob Agents Chemother. 2021 Feb 16. pii: AAC.02230.
    PubMed     Abstract available


  68. SHIRIAEV DI, Sofronova AA, Berdnikovich EA, Lukianov DA, et al
    Nybomycin inhibits both types of E. coli DNA gyrase - fluoroquinolone-sensitive and fluoroquinolone-resistant.
    Antimicrob Agents Chemother. 2021 Feb 16. pii: AAC.00777.
    PubMed     Abstract available


  69. DUMKE R
    Antimicrobial resistance in clinical isolates of Ureaplasma spp. from samples in Germany.
    Antimicrob Agents Chemother. 2021 Feb 16. pii: AAC.02342.
    PubMed     Abstract available


  70. LI L, Zhang M, Wang W, Xia R, et al
    Identification and characterization of two novel ISCR1-associated genes dfrA42 and dfrA43 encoding trimethoprim resistant dihydrofolate reductases.
    Antimicrob Agents Chemother. 2021 Feb 16. pii: AAC.02010.
    PubMed     Abstract available


    January 2021
  71. SMITH NM, Ang A, Tan F, Macias K, et al
    Interaction of Staphylococcus aureus and Acinetobacter baumannii during in vitro beta-lactam exposure.
    Antimicrob Agents Chemother. 2021 Jan 25. pii: AAC.02414.
    PubMed     Abstract available


  72. OLIVER MB, Fong K, Certain L, Spivak ES, et al
    Validation of a Community-Acquired Pneumonia Score To Improve Empiric Antibiotic Selection at an Academic Medical Center.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  73. YANG J, Liu L, Feng Y, He D, et al
    Potential Mobilization of mcr-10 by an Integrative Mobile Element via Site-Specific Recombination in Cronobacter sakazakii.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  74. KHABTHANI S, Hamel M, Baron SA, Diene SM, et al
    fosM, a New Family of Fosfomycin Resistance Genes Identified in Bacterial Species Isolated from Human Microbiota.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  75. PYBUS CA, Felder-Scott C, Obuekwe V, Greenberg DE, et al
    Cefiderocol Retains Antibiofilm Activity in Multidrug-Resistant Gram-Negative Pathogens.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  76. YIN Y, Zhang H, Zhang Y, Hu C, et al
    Fungal Zn(II)2Cys6 Transcription Factor ADS-1 Regulates Drug Efflux and Ergosterol Metabolism under Antifungal Azole Stress.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  77. MOTOS A, Li Bassi G, Pagliara F, Fernandez-Barat L, et al
    Short-Term Effects of Appropriate Empirical Antimicrobial Treatment with Ceftolozane/Tazobactam in a Swine Model of Nosocomial Pneumonia.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  78. BURNARD D, Robertson G, Henderson A, Falconer C, et al
    Burkholderia pseudomallei Clinical Isolates Are Highly Susceptible In Vitro to Cefiderocol, a Siderophore Cephalosporin.
    Antimicrob Agents Chemother. 2021;65.
    PubMed     Abstract available


  79. YANG X, Ye L, Chan EW, Zhang R, et al
    Characterization of an IncFIB/IncHI1B plasmid encoding efflux pump TMexCD1-TOprJ1 in a clinical tigecycline and carbapenem-resistant Klebsiella pneumoniae strain.
    Antimicrob Agents Chemother. 2021 Jan 19. pii: AAC.02340.
    PubMed     Abstract available


  80. CHALKER VJ, Sharratt MG, Rees C, Bell OH, et al
    Tetracycline resistance mediated by tet(M) has variable Integrative Conjugative Element composition in Mycoplasma hominis isolated in the United Kingdom from 2005-2015.
    Antimicrob Agents Chemother. 2021 Jan 19. pii: AAC.02513.
    PubMed     Abstract available


  81. PRATER AG, Mehta HH, Beabout K, Supandy A, et al
    Daptomycin resistance in Enterococcus faecium can be delayed by disruption of the LiaFSR stress response pathway.
    Antimicrob Agents Chemother. 2021 Jan 19. pii: AAC.01317.
    PubMed     Abstract available


  82. PFALLER MA, Messer SA, Deshpande LM, Rhomberg PR, et al
    Evaluation of Synergistic Activity of Isavuconazole or Voriconazole plus Anidulafungin and the Occurrence and Genetic Characterisation of Candida auris Detected in a Surveillance Program.
    Antimicrob Agents Chemother. 2021 Jan 11. pii: AAC.02031.
    PubMed     Abstract available


  83. CAZER CL, Westblade LF, Simon MS, Magleby R, et al
    Analysis of multidrug resistance in Staphylococcus aureus with a machine learning generated antibiogram.
    Antimicrob Agents Chemother. 2021 Jan 11. pii: AAC.02132.
    PubMed     Abstract available


  84. DU W, Zhai P, Wang T, Bromley MJ, et al
    The C2H2 Transcription Factor SltA Contributes to Azole Resistance by Coregulating the Expression of the Drug Target Erg11A and the Drug Efflux Pump Mdr1 in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2021 Jan 11. pii: AAC.01839.
    PubMed     Abstract available


    December 2020
  85. VALAFAR SJ
    A Systematic Review of Mutations Associated with Isoniazid Resistance Points to Continuing Evolution and Subsequent Evasion of Molecular Detection, and Potential for Emergence of Multidrug Resistance in Clinical Strains of Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2020 Dec 23. pii: AAC.02091.
    PubMed     Abstract available


  86. VIMBERG V, Cavanagh JP, Novotna M, Lenart J, et al
    Erratum for Vimberg et al., "Ribosome-Mediated Attenuation of vga(A) Expression Is Shaped by the Antibiotic Resistance Specificity of Vga(A) Protein Variants".
    Antimicrob Agents Chemother. 2020;65.
    PubMed    


  87. SOMPRASONG N, Hall CM, Webb JR, Sahl JW, et al
    Burkholderia ubonensis high-level tetracycline resistance is due to efflux pump synergy involving a novel TetA(64) resistance determinant.
    Antimicrob Agents Chemother. 2020 Dec 14. pii: AAC.01767.
    PubMed     Abstract available


  88. CHU S, Long L, Sherif R, McCormick TS, et al
    A second generation fungerp analog SCY-247, shows potent in vitro activity against Candida auris and other clinically relevant fungal isolates.
    Antimicrob Agents Chemother. 2020 Dec 14. pii: AAC.01988.
    PubMed     Abstract available


  89. MARGOT N, Ram R, Rhee M, Callebaut C, et al
    Absence of Lenacapavir (GS-6207) Phenotypic Resistance in HIV Gag Cleavage Site Mutants and in Isolates with Resistance to Existing Drug Classes.
    Antimicrob Agents Chemother. 2020 Dec 7. pii: AAC.02057.
    PubMed     Abstract available


    November 2020
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    December 2018
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    November 2018
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    October 2018
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    September 2018
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    August 2018
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    July 2018
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    Molecular analysis of resistance and detection of non-wild type strains using ECV values of Etest for amphotericin B and echinocandins for bloodstream Candida infections from a tertiary hospital in Qatar.
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    A New Locus of Drug Resistance in the Human Cytomegalovirus UL56 Gene Revealed by in vitro Exposure to Letermovir and Ganciclovir.
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    May 2018
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    Comparison of in vitro activity and MIC distributions between the novel oxazolidinone delpazolid and linezolid against multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis in China.
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    ClpA and HtpX Proteases Are Involved in Intrinsic Aminoglycoside Resistance of Stenotrophomonas maltophilia and Are Potential Aminoglycoside Adjuvant Targets.
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    In vitro and in vivo activities of DS-2969b, a novel GyrB inhibitor, and its water-soluble prodrug, DS11960558, against methicillin-resistant Staphylococcus aureus.
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    March 2018
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    The combination of tedizolid and daptomycin against methicillin-resistant Staphylococcus aureus in an in vitro model of simulated endocardial vegetations.
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    February 2018
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    GRL-079, a novel P2-Tp-THF-C5-alkylamine- and P2' -Abt-containing HIV-1 protease inhibitor, is extremely potent against multi-drug-resistant HIV-1 variants including HIVDRV(R)p51 and has a high genetic barrier against the emergence of resistant varian
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  609. LAU CH, Topp E
    Towards understanding the "proline-centric" design of a peptide-mediated macrolide resistance mechanism.
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    Investigation of multiple resistance mechanisms in voriconazole resistant Aspergillus flavus clinical isolates from a chest hospital surveillance in Delhi, India.
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  627. VILCHEZE C, Kim J, Jacobs WR Jr
    Vitamin C potentiates the killing of Mycobacterium tuberculosis by the first-line tuberculosis drugs isoniazid and rifampicin in mice.
    Antimicrob Agents Chemother. 2018 Jan 3. pii: AAC.02165.
    PubMed     Abstract available


    December 2017
  628. IKEH MAC, Fidel PL Jr, Noverr MC
    Prostaglandin E2 Receptor Antagonist with Antimicrobial Activity Against Methicillin Resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.01920.
    PubMed     Abstract available


  629. GREENFIELD BK, Shaked S, Marrs CF, Nelson P, et al
    Modeling the emergence of antibiotic resistance in the environment: an analytical solution for the minimum selection concentration.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.01686.
    PubMed     Abstract available


  630. AUNG WW, Ei PW, Nyunt WW, Htwe MM, et al
    Pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis clinical isolates in Myanmar.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.01984.
    PubMed     Abstract available


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    Antimicrobial Activity of Dalbavancin Tested against Staphylococcus aureus with Decreased Susceptibility to Glycopeptides, Daptomycin, and/or Linezolid from United States Medical Centers.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.02397.
    PubMed     Abstract available


  632. CARTER GP, Schultz MB, Baines SL, Goncalves da Silva A, et al
    Topical antibiotic use co-selects for the carriage of mobile genetic elements conferring resistance to unrelated antimicrobials in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2017 Dec 11. pii: AAC.02000.
    PubMed     Abstract available


  633. RIMBARA E, Mori S, Kim H, Suzuki M, et al
    Mutations in Genes Encoding Penicillin-Binding Proteins and Efflux Pumps Play a Role in beta-Lactam Resistance in Helicobacter cinaedi.
    Antimicrob Agents Chemother. 2017 Dec 4. pii: AAC.02036.
    PubMed     Abstract available


  634. ZHANG Y, Wang Q, Yin Y, Chen H, et al
    Epidemiology of carbapenem-resistant Enterobacteriaceae infections: report from China CRE Network.
    Antimicrob Agents Chemother. 2017 Dec 4. pii: AAC.01882.
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    Role of smeU1VWU2X Operon in the Alleviation of Oxidative Stresses and the Occurrence of Sulfamethoxazole/trimethoprim-resistant Mutants in Stenotrophomonas maltophilia.
    Antimicrob Agents Chemother. 2017 Dec 4. pii: AAC.02114.
    PubMed     Abstract available


  636. LEE H, Ahn S, Hwang NY, Jeon K, et al
    Limited Effect of Later-generation Fluoroquinolones in the Treatment of Ofloxacin-resistant and Moxifloxacin-susceptible Multidrug-resistant Tuberculosis.
    Antimicrob Agents Chemother. 2017 Dec 4. pii: AAC.01784.
    PubMed     Abstract available


    November 2017
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    Efficacy of novel anti-staphylococcal ectolysin P128 in a rat model of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia.
    Antimicrob Agents Chemother. 2017 Nov 27. pii: AAC.01358.
    PubMed     Abstract available


  638. WILLIAMSON DA, Lane CR, Easton M, Valcanis M, et al
    Increasing antimicrobial resistance in non-typhoidal Salmonella in Australia, 1979 - 2015.
    Antimicrob Agents Chemother. 2017 Nov 27. pii: AAC.02012.
    PubMed     Abstract available


  639. GOLDSTEIN EJC, Citron DM, Tyrrell KL, Leoncio E, et al
    The comparative in vitro activity of relebactam, imipenem and the combination of the two, plus six comparator antimicrobial agents against 432 strains of anaerobic organisms including imipenem-resistant strains.
    Antimicrob Agents Chemother. 2017 Nov 20. pii: AAC.01992.
    PubMed     Abstract available


  640. PATHIRANA RU, Friedman J, Norris HL, Salvatori O, et al
    Fluconazole Resistant Candida auris is Susceptible to Salivary Histatin 5 Killing and to Intrinsic Host Defenses.
    Antimicrob Agents Chemother. 2017 Nov 20. pii: AAC.01872.
    PubMed     Abstract available


  641. ABBADI BL, Villela AD, Rodrigues-Junior VS, Subtil FT, et al
    Revisiting activation of and the mechanism of resistance to the compound IQG-607 in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2017 Nov 20. pii: AAC.02222.
    PubMed     Abstract available


  642. ZHENG X, Berti AD, McCrone S, Roch M, et al
    Combination antibiotic exposure selectively alters the development of vancomycin intermediate resistance in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2017 Nov 20. pii: AAC.02100.
    PubMed     Abstract available


  643. TRUONG J, Veillette JJ, Forland SC
    Outcomes of vancomycin plus a beta-lactam versus vancomycin only for the treatment of methicillin-resistant Staphylococcus aureus bacteremia.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01554.
    PubMed     Abstract available


  644. SABET M, Tarazi Z, Rubio-Aparicio D, Nolan TG, et al
    Activity of Simulated Human Dosage Regimens of Meropenem and Vaborbactam against Carbapenem-resistant Enterobacteriaceae in an In Vitro Hollow Fiber Model.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01969.
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  645. WI YM, Greenwood-Quaintance KE, Schuetz AN, Ko KS, et al
    Activity of Ceftolozane/Tazobactam Against Carbapenem-Resistant, Carbapenemase Non-Producing Pseudomonas aeruginosa and Associated Resistance Mechanisms.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01970.
    PubMed     Abstract available


  646. BOLARD A, Plesiat P, Jeannot K
    Mutations in gene fusA1 as a novel mechanism of aminoglycoside resistance in clinical strains of Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01835.
    PubMed     Abstract available


  647. CHANDRA J, Ghannoum MA
    CD101, a Novel Echinocandin Possesses Potent Anti-biofilm Activity Against Early and Mature Candida albicans Biofilms.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01750.
    PubMed     Abstract available


  648. EL-HOSSARY EM, Forstner KU, Francois P, Baud D, et al
    A Novel Mechanism of Inactivating Antibacterial Nitro Compounds in the Human Pathogen Staphylococcus aureus by Overexpression of a NADH-dependent Flavin Nitroreductase.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01510.
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  649. HEYCKENDORF J, Andres S, Koser CU, Olaru ID, et al
    What is resistance? Impact of phenotypic versus molecular drug resistance testing on multi- and extensively drug-resistant tuberculosis therapy.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01550.
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  650. BELLEY A, Arhin FA, Moeck G
    Evaluation of Oritavancin Dosing Strategies against Vancomycin-Resistant Enterococcus faecium Isolates with or without Reduced Susceptibility to Daptomycin in an in vitro Pharmacokinetic/Pharmacodynamic Model.
    Antimicrob Agents Chemother. 2017 Nov 6. pii: AAC.01873.
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    Activity of Meropenem-Vaborbactam in Mouse Models of Infection due to KPC-producing Carbapenem-Resistant Enterobacteriaceae (CRE).
    Antimicrob Agents Chemother. 2017 Nov 6. pii: AAC.01446.
    PubMed     Abstract available


  652. GARDNER SG, Marshall DD, Daum RS, Powers R, et al
    Metabolic Mitigation of Staphylococcus aureus Vancomycin Intermediate-Level Susceptibility.
    Antimicrob Agents Chemother. 2017 Nov 6. pii: AAC.01608.
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    October 2017
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    Mutations within embCAB are associated with variable level of ethambutol resistance in Mycobacterium tuberculosis isolates from China.
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  654. WILLBY MJ, Wijkander M, Havumaki J, Johnson K, et al
    Detection of Mycobacterium tuberculosis pncA mutations by the NIPRO GenoscholarPZA-TB II as compared to conventional sequencing.
    Antimicrob Agents Chemother. 2017 Oct 30. pii: AAC.01871.
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  655. ARGUDIN MA, Roisin S, Dodemont M, Nonhoff C, et al
    Mutations at the ribosomal S10 gene in clinical strains of Staphylococcus aureus with reduced susceptibility to tigecycline.
    Antimicrob Agents Chemother. 2017 Oct 30. pii: AAC.01852.
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  656. DE SILVA PM, Chong P, Fernando DM, Westmacott G, et al
    Effect of incubation temperature on antibiotic resistance and virulence factors of Acinetobacter baumannii ATCC 17978.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.01514.
    PubMed     Abstract available


  657. DAL MOLIN M, Gut M, Rominski A, Haldimann K, et al
    Molecular Mechanisms of Intrinsic Streptomycin Resistance in Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.01427.
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  658. SAPUTO S, Faustoferri RC, Quivey RG Jr
    Vitamin D compounds are bactericidal against Streptococcus mutans and target the bacitracin-associated efflux system.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.01675.
    PubMed     Abstract available


  659. BHARDWAJ P, Hans A, Ruikar K, Guan Z, et al
    Reduced chlorhexidine and daptomycin susceptibility in vancomycin-resistant Enterococcus faecium after serial chlorhexidine exposure.
    Antimicrob Agents Chemother. 2017 Oct 16. pii: AAC.01235.
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  660. JONES D, Elshaboury RH, Munson E, Dilworth TJ, et al
    A Retrospective Analysis of Treatment and Clinical Outcomes among Patients with Methicillin-susceptible Staphylococcus aureus Bloodstream Isolates Possessing Detectable mecA by a Commercial PCR Assay Compared to Patients with Methicillin-resistant Sta
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    Activity of Meropenem-Vaborbactam Against Carbapenem-resistant Enterobacteriaceae in a Murine Model of Pyelonephritis.
    Antimicrob Agents Chemother. 2017 Oct 16. pii: AAC.01439.
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  662. VAN LOON K, Voor In 't Holt AF, Vos MC
    Clinical epidemiology of carbapenem-resistant Enterobacteriaceae: a systematic review and meta-analyses.
    Antimicrob Agents Chemother. 2017 Oct 16. pii: AAC.01730.
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  663. ACCOCEBERRY I, Rougeron A, Biteau N, Chevrel P, et al
    A CTG clade Candida yeast genetically engineered for the genotype-phenotype characterization of azole antifungal resistance in human pathogenic yeasts.
    Antimicrob Agents Chemother. 2017 Oct 16. pii: AAC.01483.
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  664. XU J, Tasneen R, Peloquin CA, Almeida DV, et al
    Verapamil increases the bioavailability and efficacy of bedaquiline but not clofazimine in a murine model of tuberculosis.
    Antimicrob Agents Chemother. 2017 Oct 16. pii: AAC.01692.
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  665. RAFFETIN A, Courbin V, Jullien V, Dannaoui E, et al
    In vitro combination of Isavuconazole with Echinocandins against Azole-Susceptible and -Resistant Aspergillus spp.
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  666. HUMPHRIES RM, Hindler JA, Wong-Beringer A, Miller SA, et al
    Activity of ceftolozane-tazobactam and ceftazidime-avibactam against beta-lactam resistant Pseudomonas aeruginosa isolates.
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  667. DE WELZEN L, Eldholm V, Maharaj K, Manson AL, et al
    Whole transcriptome and genomic analysis of extensively drug-resistant Mycobacterium tuberculosis clinical isolates identifies downregulation of ethA as a mechanism of ethionamide resistance.
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  668. MOUSAVI SF, Pana M, Feizabadi M, Jalali P, et al
    Diversity of mosaic pbp2x families of penicillin-resistant Streptococcus pneumoniae from Iran and Romania.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01535.
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    Risk Factors for Colonization or Infection with Carbapenem-Resistant Enterobacteriaceae in Children: a Multicenter Study.
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  670. NAKATANI Y, Opel-Reading HK, Merker M, Machado D, et al
    Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01575.
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  671. HEALEY KR, Nagasaki Y, Zimmerman M, Kordalewska M, et al
    The gastrointestinal tract is a major source of echinocandin drug resistance in a murine model of Candida glabrata colonization and systemic dissemination.
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    PubMed     Abstract available


    September 2017
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    Co-location of the multiresistance gene cfr and the fosfomycin resistance gene fosD on a novel plasmid in Staphylococcus arlettae from chicken farm.
    Antimicrob Agents Chemother. 2017 Sep 18. pii: AAC.01388.
    PubMed     Abstract available


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    Antiviral Activity of Bictegravir and Cabotegravir Against Integrase Inhibitor Resistant SIVmac239 and HIV-1.
    Antimicrob Agents Chemother. 2017 Sep 18. pii: AAC.01695.
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  674. BUIL JB, van der Lee HAL, Rijs AJMM, Zoll J, et al
    AGAR-BASED SCREENING FOR AZOLE RESISTANCE IN ASPERGILLUS FUMIGATUS USING VIPcheck: A SINGLE CENTRE EVALUATION.
    Antimicrob Agents Chemother. 2017 Sep 18. pii: AAC.01250.
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  675. JIMENEZ-ORTIGOSA C, Moore C, Denning DW, Perlin DS, et al
    Emergence of Echinocandin Resistance due to a Point Mutation in the fks1 Gene of Aspergillus fumigatus in a Patient with Chronic Pulmonary Aspergillosis.
    Antimicrob Agents Chemother. 2017 Sep 18. pii: AAC.01277.
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  676. XU W, DeJesus MA, Rucker N, Engelhart CA, et al
    Chemical genomic interaction profiling reveals determinants of intrinsic antibiotic resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.01334.
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  677. KNOPPEL A, Nasvall J, Andersson DI
    Evolution of antibiotic resistance without antibiotic exposure.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.01495.
    PubMed     Abstract available


  678. METCALFE JZ, Streicher E, Theron G, Colman RE, et al
    Mycobacterium tuberculosis subculture results in loss of potentially clinically relevant heteroresistance.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.00888.
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  679. NEGRI CE, Goncalves SS, Sousa ACP, Bergamasco MD, et al
    Triazole resistance is still not emerging in A fumigatus isolates causing invasive aspergillosis in Brazilian patients.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.00608.
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  680. ZHAO N, Wang G, Das AT, Berkhout B, et al
    Combinatorial CRISPR-Cas9 and RNAi attack on HIV-1 DNA and RNA can lead to cross-resistance.
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  681. BERNAL-MARTINEZ L, Gil H, Rivero-Menendez O, Gago S, et al
    Development and validation of a High Resolution Melting Assay to detect azole resistance in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.01083.
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  682. HOBDEY SE, Katahira EJ, Dockstader P, Davidson SM, et al
    Subinhibitory Dalbavancin Attenuates Exotoxin Production from Methicillin-sensitive and Methicillin-resistant Staphylococcus aureus in vitro.
    Antimicrob Agents Chemother. 2017 Sep 5. pii: AAC.01090.
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  683. HURST-HESS K, Rudra P, Ghosh P
    Mycobacterium abscessus WhiB7 regulates a species -specific repertoire of genes to confer extreme antibiotic resistance.
    Antimicrob Agents Chemother. 2017 Sep 5. pii: AAC.01347.
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  684. SCHNIEDERJANS M, Koska M, Haussler S
    Transcriptional and mutational profiling of an aminoglycoside resistant Pseudomonas aeruginosa small colony variant.
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  685. PARK SW, Tasneen R, Converse PJ, Nuermberger EL, et al
    Immunodeficiency and Intermittent Dosing Promote Acquired Rifamycin Monoresistance in Murine Tuberculosis.
    Antimicrob Agents Chemother. 2017 Sep 5. pii: AAC.01502.
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    August 2017
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    When Good Bugs Go Bad: Epidemiology and Antimicrobial Resistance Profiles of Corynebacterium striatum, an Emerging Multidrug Resistant, Opportunistic Pathogen.
    Antimicrob Agents Chemother. 2017 Aug 28. pii: AAC.01111.
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  687. SHEKHOVA E, Kniemeyer O, Brakhage AA
    Induction of mitochondrial ROS production by itraconazole, terbinafine and amphotericin B as a mode of action against Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2017 Aug 28. pii: AAC.00978.
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  688. FAKHIM H, Chowdhary A, Prakash A, Vaezi A, et al
    In Vitro Interactions of Echinocandins with Triazoles Against Multidrug-Resistant Candida auris.
    Antimicrob Agents Chemother. 2017 Aug 28. pii: AAC.01056.
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  689. VALENTINE-KING MA, Brown MB
    Antibacterial Resistance in Ureaplasma species and Mycoplasma hominis Isolates from Urine Cultures in College-aged Females.
    Antimicrob Agents Chemother. 2017 Aug 21. pii: AAC.01104.
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  690. KATAYAMA Y, Azechi T, Miyazaki M, Takata T, et al
    Prevalence of Slow-growth Vancomycin Non-susceptibility In Methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2017 Aug 21. pii: AAC.00452.
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  691. CHOU S
    Comparison of Cytomegalovirus Terminase Gene Mutations Selected after Exposure to Three Distinct Inhibitor Compounds.
    Antimicrob Agents Chemother. 2017 Aug 21. pii: AAC.01325.
    PubMed     Abstract available


  692. SCHELL WA, Jones AM, Borroto-Esoda K, Alexander BD, et al
    Antifungal Activity of SCY-078 and Standard Antifungal Agents Against 178 Clinical Isolates of Resistant and Susceptible Candida Species.
    Antimicrob Agents Chemother. 2017 Aug 21. pii: AAC.01102.
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  693. CHEUNG YY, Hui M
    Effects of Echinocandins in combination with Nikkomycin Z against invasive Candida albicans bloodstream isolates and the fks mutants.
    Antimicrob Agents Chemother. 2017 Aug 21. pii: AAC.00619.
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  694. CHATTERJEE SS, Chen L, Gilbert A, da Costa TM, et al
    PBP4 mediates beta-lactam resistance by altered function.
    Antimicrob Agents Chemother. 2017 Aug 14. pii: AAC.00932.
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  695. TSAY FW, Wu DC, Yu HC, Kao SS, et al
    Both 14-day hybrid and bismuth quadruple therapies cure most patients with Helicobacter pylori infection in populations with moderate antibiotic resistance: a randomized controlled trial.
    Antimicrob Agents Chemother. 2017 Aug 14. pii: AAC.00140.
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  696. MELETIADIS J, Turlej-Rogacka A, Lerner A, Adler A, et al
    Amplification of Antimicrobial Resistance in Gut Flora of Patients Treated with Ceftriaxone.
    Antimicrob Agents Chemother. 2017 Aug 14. pii: AAC.00473.
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  697. LIU Z, Myers LC
    Candida albicans Swi/Snf and Mediator Complexes Differentially Regulate Mrr1-induced MDR1 Expression and Fluconazole Resistance.
    Antimicrob Agents Chemother. 2017 Aug 14. pii: AAC.01344.
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  698. LIU Z, Myers LC
    Mediator Tail Module is Required for Tac1 Activated CDR1 Expression and Azole Resistance in Candida albicans.
    Antimicrob Agents Chemother. 2017 Aug 14. pii: AAC.01342.
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  699. PIRET J, Goyette N, Boivin G
    Drug Susceptibility and Replicative Capacity of Multi-Drug Resistant Recombinant Human Cytomegalovirus Harboring Mutations in UL56 and UL54 Genes.
    Antimicrob Agents Chemother. 2017 Aug 14. pii: AAC.01044.
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  700. MCBRIDE JM, Lim JJ, Burgess T, Deng R, et al
    Safety and Efficacy of MHAA4549A, a Broadly Neutralizing Monoclonal Antibody, in a Human Influenza A Challenge Model: A Phase 2 Randomized Trial.
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  701. RENZONI A, Von Dach E, Landelle C, Diene SM, et al
    Impact of exposure of methicillin-resistant Staphylococcus aureus to polyhexanide in vitro and in vivo.
    Antimicrob Agents Chemother. 2017 Aug 7. pii: AAC.00272.
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  702. BELLEY A, Lalonde-Seguin D, Arhin FF, Moeck G, et al
    Comparative Pharmacodynamics of Single-Dose Oritavancin and Daily High-Dose Daptomycin Regimens against Vancomycin-resistant Enterococcus faecium Isolates in an In Vitro PK/PD Model of Infection.
    Antimicrob Agents Chemother. 2017 Aug 7. pii: AAC.01265.
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  703. TYSON GH, Tate HP, Zhao S, Li C, et al
    Identification of Plasmid-Mediated Quinolone Resistance in Salmonella Isolated from Swine Ceca and Retail Pork Chops in the United States.
    Antimicrob Agents Chemother. 2017 Aug 7. pii: AAC.01318.
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  704. CASTANHEIRA M, Deshpande LM, Davis AP, Rhomberg PR, et al
    Monitoring Antifungal Resistance in a Global Collection of Invasive Yeasts and Moulds: Application of CLSI Epidemiological Cutoff Values and Whole Genome Sequencing Analysis for Detection of Azole Resistance in Candida albicans.
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    Progressive Dispersion of Azole Resistance in Aspergillus fumigatus: Fatal Invasive Aspergillosis in a Patient with Acute Myeloid Leukemia Infected with an A. fumigatus Strain with a cyp51A TR46 Y121F M172I T289A Allele.
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    July 2017
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    Molecular characterization of fluoroquinolone-resistant Moraxella catarrhalis variants generated in vitro by stepwise selection.
    Antimicrob Agents Chemother. 2017 Jul 31. pii: AAC.01336.
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  707. MCNEIL MB, Dennison D, Shelton C, Parish T, et al
    In vitro isolation and characterization of oxazolidinone resistant Mycobacterium tuberculosis.
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  708. CHHIBBER S, Shukla A, Kaur S
    Transfersomal phage cocktail: an effective treatment against methicillin resistant S.aureus (MRSA) mediated Skin and Soft tissue infections (SSTIs).
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    Clinical Characteristics and Treatment Outcomes of Patients with Acquired Macrolide-resistant Mycobacterium abscessus Lung Disease.
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    Contribution of TetB Efflux Pump on Minocycline Susceptibility among Carbapenem-Resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2017 Jul 24. pii: AAC.01176.
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  711. JUKIC E, Blatzer M, Posch W, Steger M, et al
    Oxidative stress response tips the balance in Aspergillus terreus AmB resistance.
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    In vitro drug susceptibility of bedaquiline, delamanid, linezolid, clofazimine, moxifloxacin, and gatifloxacin against extensively drug -resistant tuberculosis from Beijing, China.
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  713. GALLAGHER LA, Coughlan S, Black NS, Lalor P, et al
    Tandem amplification of SCCmec can drive high level methicillin resistance in MRSA.
    Antimicrob Agents Chemother. 2017 Jul 17. pii: AAC.00869.
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    Evaluation of Combination Drug Therapy for Treatment of Antibiotic Resistant Inhalation Anthrax in a Murine Model.
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  715. HAZEN TH, Michalski J, Nagaraj S, Okeke IN, et al
    Characterization of a large antibiotic resistance plasmid found in enteropathogenic Escherichia coli strain B171 and its relatedness to plasmids of diverse E. coli and Shigella.
    Antimicrob Agents Chemother. 2017 Jul 3. pii: AAC.00995.
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  716. HEINE HS, Miller L, Halasohoris S, Purcell BK, et al
    In Vitro Antibiotic Susceptibilities of Francisella tularensis by Broth Micro-Dilution Following CLSI Methods.
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  717. HENNEBIQUE A, Bidart M, Jarraud S, Beraud L, et al
    Digital PCR for detection and quantification of fluoroquinolone resistance in Legionella pneumophila.
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  718. LONG TE
    Repurposing thiram and disulfiram as antibacterial agents for multi-drug resistant Staphylococcus aureus infections.
    Antimicrob Agents Chemother. 2017 Jul 3. pii: AAC.00898.
    PubMed     Abstract available


  719. PATEL N, O'Malley T, Zhang YK, Xia Y, et al
    A novel 6-benzyl ether benzoxaborole is active against Mycobacterium tuberculosis in vitro.
    Antimicrob Agents Chemother. 2017 Jul 3. pii: AAC.01205.
    PubMed     Abstract available


    June 2017
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    Meropenem-Vaborbactam Tested against Contemporary Gram-Negative Isolates Collected Worldwide During 2014, Including Carbapenem-Resistant, KPC-Producing, Multidrug-Resistant, and Extensively Drug-Resistant Enterobacteriaceae.
    Antimicrob Agents Chemother. 2017 Jun 26. pii: AAC.00567.
    PubMed     Abstract available


  721. FERRER-GONZALEZ E, Kaul M, Parhi AK, LaVoie EJ, et al
    beta-Lactam Antibiotics with a High Affinity for PBP2 Act Synergistically with the FtsZ-Targeting Agent TXA707 against Methicillin-Resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2017 Jun 19. pii: AAC.00863.
    PubMed     Abstract available


  722. KIM CK, Milheirico C, de Lencastre H, Tomasz A, et al
    Antibiotic resistance as a stress response: recovery of high-level oxacillin resistance in methicillin resistant S. aureus (MRSA) "auxiliary" (fem) mutants - by induction of the stringent stress response.
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  723. HAIDAR G, Clancy CJ, Chen L, Samanta P, et al
    Identifying spectra of activity and therapeutic niches for ceftazidime-avibactam and imipenem-relebactam against carbapenem-resistant Enterobacteriaceae.
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  724. CHIBA N, Murayama SY, Morozumi M, Iwata S, et al
    Genome Evolution to Penicillin Resistance in Serotype 3 Streptococcus pneumoniae by Capsular Switching.
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  725. DAVIDO B, Fellous L, Lawrence C, Maxime V, et al
    Ceftazidime-Avibactam and Aztreonam an interesting strategy to Overcome beta-Lactam Resistance Conferred by Metallo-beta-Lactamases in Enterobacteriaceae and Pseudomonas aeruginosa.
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  726. MATSUMOTO S, Singley CM, Hoover J, Nakamura R, et al
    Efficacy of Cefiderocol against Carbapenem-resistant Gram-negative bacilli in Immunocompetent Rat Respiratory Tract Infection Models Recreating Human Plasma pharmacokinetics.
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  727. RAHMAN A, Ferdous SS, Ahmed S, Rahman SMM, et al
    Pyrazinamide susceptibility and pncA mutation profile of Mycobacterium tuberculosis among multi-drug resistant tuberculosis patients in Bangladesh.
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  728. JIMENEZ-ORTIGOSA C, Perez WB, Angulo D, Borroto-Esoda K, et al
    De novo acquisition of resistance to SCY-078 in Candida glabrata involves FKS mutations that both overlap and are distinct from those conferring echinocandin resistance.
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  729. RYBAK JM, Dickens CM, Parker JE, Caudle K, et al
    Loss of C-5 sterol desaturase activity results in increased resistance to azole and echinocandin antifungals in a clinical isolate of Candida parapsilosis.
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    PubMed     Abstract available


  730. BABLISHVILI N, Tukvadze N, Shashkina E, Mathema B, et al
    The impact of gyrB and eis mutations in improving second-line drug resistance detection among Mycobacterium tuberculosis isolates from Georgia.
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  731. TODD DA, Parlet CP, Crosby HA, Malone CL, et al
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  732. RODRIGUES FELIX C, Gupta R, Geden S, Roberts J, et al
    Selective Killing Of Dormant Mycobacterium tuberculosis By Marine Natural Products.
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  733. HASHIMOTO A, Hagiwara D, Watanabe A, Yahiro M, et al
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  734. LI DD, Chai D, Huang XW, Guan SX, et al
    Potent In Vitro Synergism of Fluconazole and Osthole against Fluconazole-Resistant Candida albicans.
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  735. ZHANG Y, Zhang J, Cui P, Zhang W, et al
    Identification of novel efflux proteins Rv0191, Rv3756c, Rv3008 and Rv1667c involved in pyrazinamide resistance in Mycobacterium tuberculosis.
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    PubMed     Abstract available


  736. HALL CW, Zhang L, Mah TF
    PA3225 is a transcriptional repressor of antibiotic resistance mechanisms in Pseudomonas aeruginosa.
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    PubMed     Abstract available


  737. KLEINERT F, Kallies R, Hort M, Zweynert A, et al
    Influence of IS256 on genome variability and formation of SCV in Staphylococcus aureus.
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  738. LEPAK AJ, Zhao M, Berkow EL, Lockhart SR, et al
    Pharmacodynamic Optimization for Treatment of Invasive Candida auris Infection.
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  739. SRIVASTAVA S, Magombedze G, Koeuth T, Sherman C, et al
    Linezolid dose that maximizes sterilizing effect while minimizing toxicity and resistance emergence for tuberculosis.
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  740. LE A, Farmakiotis D, Tarrand JJ, Kontoyiannis DP, et al
    Initial treatment of cancer patients with fluconazole susceptible dose-dependent Candida glabrata fungemia: Better outcome with an echinocandin or polyene compared to an azole?
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  741. AZIZ DB, Low JL, Wu ML, Gengenbacher M, et al
    Rifabutin Is Active against Mycobacterium abscessus Complex.
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  742. LIU X, Li R, Zheng Z, Chen K, et al
    Molecular Characterization of Escherichia coli Isolates Carrying mcr-1, fosA3, and Extended-Spectrum-beta-Lactamase Genes from Food Samples in China.
    Antimicrob Agents Chemother. 2017;61.
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  743. CRUZ-OLIVEIRA C, Almeida AF, Freire JM, Caruso MB, et al
    Mechanisms of Vesicular Stomatitis Virus Inactivation by Protoporphyrin IX, Zinc-Protoporphyrin IX, and Mesoporphyrin IX.
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  744. SHEA KM, Hobbs ALV, Jaso TC, Bissett JD, et al
    Effect of a Health Care System Respiratory Fluoroquinolone Restriction Program To Alter Utilization and Impact Rates of Clostridium difficile Infection.
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  745. KIEFFER N, Nordmann P, Poirel L
    Moraxella Species as Potential Sources of MCR-Like Polymyxin Resistance Determinants.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


  746. KISHII R, Yamaguchi Y, Takei M
    In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977).
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  747. FLEEMAN R, Van Horn KS, Barber MM, Burda WN, et al
    Characterizing the Antimicrobial Activity of N(2),N(4)-Disubstituted Quinazoline-2,4-Diamines toward Multidrug-Resistant Acinetobacter baumannii.
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  748. BARDET L, Baron S, Leangapichart T, Okdah L, et al
    Deciphering Heteroresistance to Colistin in a Klebsiella pneumoniae Isolate from Marseille, France.
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  749. OVEJERO CM, Escudero JA, Thomas-Lopez D, Hoefer A, et al
    Highly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals.
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  750. LIU YY, Chandler CE, Leung LM, McElheny CL, et al
    Structural Modification of Lipopolysaccharide Conferred by mcr-1 in Gram-Negative ESKAPE Pathogens.
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  751. MA Q, Xu X, Luo M, Wang J, et al
    A Waterborne Outbreak of Shigella sonnei with Resistance to Azithromycin and Third-Generation Cephalosporins in China in 2015.
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  752. WIND CM, Bruisten SM, Schim van der Loeff MF, Dierdorp M, et al
    A Case-Control Study of Molecular Epidemiology in Relation to Azithromycin Resistance in Neisseria gonorrhoeae Isolates Collected in Amsterdam, the Netherlands, between 2008 and 2015.
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    May 2017
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    Prevalence of Invasive Infections due to Carbapenem-Resistant Enterobacteriaceae Among Adult Patients Across US Hospitals.
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  754. ZHANG Y, Kashikar A, Brown CA, Denys G, et al
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  755. SHIELDS RK, Nguyen MH, Chen L, Press EG, et al
    Ceftazidime-avibactam is superior to other treatment regimens against carbapenem-resistant Klebsiella pneumoniae bacteremia.
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  756. WU VH, Smith RA, Masoum S, Raugi DN, et al
    MK-8591 (4' -ethynyl-2-fluoro-2' -deoxyadenosine) exhibits potent activity against HIV-2 isolates and drug-resistant HIV-2 mutants in culture.
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  757. AIGNER M, Erbeznik T, Gschwentner M, Lass-Florl C, et al
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    Roles of ramR and tet(A) mutations in conferring tigecycline resistance in carbapenem-resistant Klebsiella pneumoniae clinical isolates.
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  759. MARVAUD JC, Lambert T
    Arr-cb, a rifampin resistance determinant found active or cryptic in Clostridium bolteae.
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    PubMed     Abstract available


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    Antimicrobial Resistance Risks of Cholera Prophylaxis for United Nations Peacekeepers.
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    Impact of HIV-1 Integrase L74F/V75I Mutations from a Clinical Isolate on Resistance to Second-Generation Integrase Strand Transfer Inhibitors.
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    ERG11 gene mutations and MDR1 up-regulation confer pan-azole-resistance in Candida tropicalis causing disseminated candidiasis while on posaconazole prophylaxis in an acute lymphoblastic leukemia patient.
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    PubMed     Abstract available


  765. GIACOBBI NS, Sluis-Cremer N
    In Vitro Cross-Resistance Profiles of Rilpivirine, Dapivirine and MIV-150: NNRTI Microbicides in Clinical Development for the Prevention of HIV-1 Infection.
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    New aspects of the interplay between penicillin binding proteins, murM and the two component system CiaRH of penicillin-resistant Streptococcus pneumoniae serotype 19A isolates from Hungary.
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  767. KING M, Heil E, Kuriakose S, Bias T, et al
    Outcomes with ceftazidime/avibactam in patients with carbapenem-resistant Enterobacteriaceae (CRE) infections: a multi-center study.
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    PubMed     Abstract available


  768. DUPONT H, Choinier P, Roche D, Adiba S, et al
    Structural Alteration of OmpR as a Source of Ertapenem Resistance in a CTX-M-15-Producing Escherichia coli O25b:H4 Sequence Type 131 Clinical Isolate.
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    Colistin Resistance Gene mcr-1 and Its Variant in Escherichia coli Isolates from Chickens in China.
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    In Vitro Selection of Meropenem Resistance among Ceftazidime-Avibactam-Resistant, Meropenem-Susceptible Klebsiella pneumoniae Isolates with Variant KPC-3 Carbapenemases.
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    WCK 5222 (Cefepime-Zidebactam) Antimicrobial Activity against Clinical Isolates of Gram-Negative Bacteria Collected Worldwide in 2015.
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  772. TURANO H, Gomes F, Barros-Carvalho GA, Lopes R, et al
    Tn6350, a Novel Transposon Carrying Pyocin S8 Genes Encoding a Bacteriocin with Activity against Carbapenemase-Producing Pseudomonas aeruginosa.
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  773. SNESRUD E, Ong AC, Corey B, Kwak YI, et al
    Analysis of Serial Isolates of mcr-1-Positive Escherichia coli Reveals a Highly Active ISApl1 Transposon.
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    Surveillance of Omadacycline Activity against Clinical Isolates from a Global Collection (North America, Europe, Latin America, Asia-Western Pacific), 2010-2011.
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  775. DAI Y, Chang W, Zhao C, Peng J, et al
    VraR Binding to the Promoter Region of agr Inhibits Its Function in Vancomycin-Intermediate Staphylococcus aureus (VISA) and Heterogeneous VISA.
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  776. LU X, Hu Y, Luo M, Zhou H, et al
    MCR-1.6, a New MCR Variant Carried by an IncP Plasmid in a Colistin-Resistant Salmonella enterica Serovar Typhimurium Isolate from a Healthy Individual.
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    First Report of the Carbapenemase Gene blaOXA-499 in Acinetobacter pittii.
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  778. OSTROSKY-ZEICHNER L, Harrington R, Azie N, Yang H, et al
    A Risk Score for Fluconazole Failure among Patients with Candidemia.
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    Complete Nucleotide Sequences of Two VIM-1-Encoding Plasmids from Klebsiella pneumoniae and Leclercia adecarboxylata Isolates of Czech Origin.
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  780. PANG Y, Zheng H, Tan Y, Song Y, et al
    In Vitro Activity of Bedaquiline against Nontuberculous Mycobacteria in China.
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  781. GENG X, Li W, Chen Z, Gao S, et al
    The Bifunctional Enzyme SpoT Is Involved in the Clarithromycin Tolerance of Helicobacter pylori by Upregulating the Transporters HP0939, HP1017, HP0497, and HP0471.
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  782. NOVOVIC K, Trudic A, Brkic S, Vasiljevic Z, et al
    Molecular Epidemiology of Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae in Serbia from 2013 to 2016.
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  783. CHARRIER C, Salisbury AM, Savage VJ, Duffy T, et al
    Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria.
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    Chicken Meat as a Reservoir of Colistin-Resistant Escherichia coli Strains Carrying mcr-1 Genes in South America.
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  785. NG TI, Krishnan P, Pilot-Matias T, Kati W, et al
    In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS5A Inhibitor Pibrentasvir.
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    Vitamin K3 Induces the Expression of the Stenotrophomonas maltophilia SmeVWX Multidrug Efflux Pump.
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  787. HAIDAR G, Clancy CJ, Shields RK, Hao B, et al
    Mutations in blaKPC-3 That Confer Ceftazidime-Avibactam Resistance Encode Novel KPC-3 Variants That Function as Extended-Spectrum beta-Lactamases.
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    Prevalence and Molecular Characterization of mcr-1-Positive Salmonella Strains Recovered from Clinical Specimens in China.
    Antimicrob Agents Chemother. 2017;61.
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  789. POPP C, Hampe I, Hertlein T, Ohlsen K, et al
    Competitive fitness of fluconazole-resistant, clinical Candida albicans strains.
    Antimicrob Agents Chemother. 2017 May 1. pii: AAC.00584.
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  790. MORALES-LOPEZ S, Dudiuk C, Vivot W, Szusz W, et al
    Phenotypic and molecular evaluation of echinocandin susceptibility of Candida glabrata, Candida bracarensis and Candida nivariensis strains isolated during 30 years in Argentina.
    Antimicrob Agents Chemother. 2017 May 1. pii: AAC.00170.
    PubMed     Abstract available


    April 2017
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    New macrolide-lincosamide-streptogramin B resistance gene erm(48) on the novel plasmid pJW2311 in Staphylococcus xylosus.
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    Candida guilliermondii complex is characterized by high antifungal resistance but low mortality: a report on 22 cases of candidemia.
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    Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.
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    Evaluation of a multi-drug assay for monitoring adherence to a regimen for HIV pre-exposure prophylaxis in a clinical study (HIV Prevention Trials Network 073).
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  795. VISWANATHAN G, Yadav S, Raghunand TR
    Identification of mycobacterial genes involved in antibiotic sensitivity - Implications in the treatment of tuberculosis with beta-lactam containing regimens.
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    In vivo efficacy of liposomal amphotericin B against wild type and azole-resistant Aspergillus fumigatus isolates in two different immunosuppressed models of invasive aspergillosis.
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  798. JANG J, Kim R, Woo M, Jeong J, et al
    Efflux attenuates the anti-bacterial activity of Q203 in Mycobacterium tuberculosis.
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    Antibiotic Resistance Markers in Strain Bp1651 of Burkholderia pseudomallei Identified by Genome Sequence Analysis.
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  800. DAS K, Martinez SE, Arnold E
    Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex that Confer Multi-Nucleoside Drug Resistance.
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    AUC/MIC pharmacodynamic target is not a good predictor of vancomycin efficacy in methicillin-resistant Staphylococcus aureus (MRSA) experimental endocarditis.
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    The antimicrobial effects of beta-lactams on imipenem-resistant ceftazidime-susceptible Pseudomonas aeruginosa.
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    A Whole-Genome Sequencing Approach To Study Cefoxitin-Resistant Salmonella enterica Serovar Heidelberg Isolates from Various Sources.
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  810. ESTEBAN-CANTOS A, Aracil B, Bautista V, Ortega A, et al
    The Carbapenemase-Producing Klebsiella pneumoniae Population Is Distinct and More Clonal than the Carbapenem-Susceptible Population.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


  811. BABY N, Faust AC, Smith T, Sheperd LA, et al
    Nasal Methicillin-Resistant Staphylococcus aureus (MRSA) PCR Testing Reduces the Duration of MRSA-Targeted Therapy in Patients with Suspected MRSA Pneumonia.
    Antimicrob Agents Chemother. 2017;61.
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  812. HARTL R, Kerschner H, Lepuschitz S, Ruppitsch W, et al
    Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


  813. LERKSUTHIRAT T, Sangcakul A, Lohnoo T, Yingyong W, et al
    Evolution of the Sterol Biosynthetic Pathway of Pythium insidiosum and Related Oomycetes Contributes to Antifungal Drug Resistance.
    Antimicrob Agents Chemother. 2017;61.
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  814. SUN P, Bi Z, Nilsson M, Zheng B, et al
    Occurrence of blaKPC-2, blaCTX-M, and mcr-1 in Enterobacteriaceae from Well Water in Rural China.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


  815. GROHS P, Taieb G, Morand P, Kaibi I, et al
    In Vitro Activity of Ceftolozane-Tazobactam against Multidrug-Resistant Nonfermenting Gram-Negative Bacilli Isolated from Patients with Cystic Fibrosis.
    Antimicrob Agents Chemother. 2017;61.
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  816. JONES AK, Woods AL, Takeoka KT, Shen X, et al
    Determinants of Antibacterial Spectrum and Resistance Potential of the Elongation Factor G Inhibitor Argyrin B in Key Gram-Negative Pathogens.
    Antimicrob Agents Chemother. 2017;61.
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  817. HALLOUM I, Viljoen A, Khanna V, Craig D, et al
    Resistance to Thiacetazone Derivatives Active against Mycobacterium abscessus Involves Mutations in the MmpL5 Transcriptional Repressor MAB_4384.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


  818. MARTIN-GUTIERREZ G, Rodriguez-Martinez JM, Pascual A, Rodriguez-Beltran J, et al
    Plasmidic qnr Genes Confer Clinical Resistance to Ciprofloxacin under Urinary Tract Physiological Conditions.
    Antimicrob Agents Chemother. 2017;61.
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  819. HACHEM R, Reitzel R, Rolston K, Chaftari AM, et al
    Antimicrobial Activities of Ceftazidime-Avibactam and Comparator Agents against Clinical Bacteria Isolated from Patients with Cancer.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


  820. CAHILL ST, Cain R, Wang DY, Lohans CT, et al
    Cyclic Boronates Inhibit All Classes of beta-Lactamases.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


  821. SADER HS, Castanheira M, Flamm RK
    Antimicrobial Activity of Ceftazidime-Avibactam against Gram-Negative Bacteria Isolated from Patients Hospitalized with Pneumonia in U.S. Medical Centers, 2011 to 2015.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


    March 2017
  822. PETERS BM, Luna-Tapia A, Tournu H, Rybak JM, et al
    An azole tolerant endosomal trafficking mutant of Candida albicans is susceptible to azole treatment in a mouse model of vaginal candidiasis.
    Antimicrob Agents Chemother. 2017 Mar 27. pii: AAC.00084.
    PubMed     Abstract available


  823. VEMULA H, Ayon NJ, Burton A, Gutheil WG, et al
    Antibiotic Effects on Methicillin Resistant Staphylococcus aureus Cytoplasmic Peptidoglycan Intermediate Levels; Evidence for Potential Metabolite Level Regulatory Loops.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02253.
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  824. WANGKHEIMAYUM J, Paul D, Dhar D, Nepram R, et al
    Occurrence of acquired 16s methyltransferase mediated aminoglycoside resistance in clinical isolates of enterobacteriaceae within a tertiary referral hospital of northeast India.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.01037.
    PubMed     Abstract available


  825. MANGAT CS, Bekal S, Irwin RJ, Mulvey MR, et al
    A novel hybrid plasmid carrying multiple antimicrobial resistance and virulence genes in Salmonella Dublin.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02601.
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  826. MOYA B, Barcelo IM, Bhagwat S, Patel M, et al
    WCK 5107 (Zidebactam) & WCK 5153: Novel inhibitors of PBP2 showing potent "beta-lactam enhancer" activity against Pseudomonas aeruginosa, including multidrug-resistant metallo-beta-lactamase-producing high-risk clones.
    Antimicrob Agents Chemother. 2017 Mar 13. pii: AAC.02529.
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  827. PAUL S, Diekema D, Moye-Rowley WS
    Contributions of both ATP-binding cassette transporter and Cyp51A proteins are essential for azole resistance in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2017 Mar 6. pii: AAC.02748.
    PubMed     Abstract available


  828. GARCIA-DE-LA-MARIA C, Xiong YQ, Pericas JM, Armero Y, et al
    Impact of High-Level Daptomycin-Resistance in Streptococcus mitis group on Virulence and Survivability during Daptomycin Treatment in Experimental Infective Endocarditis.
    Antimicrob Agents Chemother. 2017 Mar 6. pii: AAC.02418.
    PubMed     Abstract available


  829. MILHEIRICO C, de Lencastre H, Tomasz A
    Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel mecC Gene.
    Antimicrob Agents Chemother. 2017;61.
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  830. DORTET L, Girlich D, Virlouvet AL, Poirel L, et al
    Characterization of BRPMBL, the Bleomycin Resistance Protein Associated with the Carbapenemase NDM.
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  831. SADER HS, Huband MD, Castanheira M, Flamm RK, et al
    Pseudomonas aeruginosa Antimicrobial Susceptibility Results from Four Years (2012 to 2015) of the International Network for Optimal Resistance Monitoring Program in the United States.
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  832. LIU BT, Song FJ, Zou M, Zhang QD, et al
    High Incidence of Escherichia coli Strains Coharboring mcr-1 and blaNDM from Chickens.
    Antimicrob Agents Chemother. 2017;61.
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  833. TADA T, Shrestha S, Shimada K, Ohara H, et al
    PER-8, a Novel Extended-Spectrum beta-Lactamase PER Variant, from an Acinetobacter baumannii Clinical Isolate in Nepal.
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  834. CASTANHEIRA M, Mendes RE, Sader HS
    Low Frequency of Ceftazidime-Avibactam Resistance among Enterobacteriaceae Isolates Carrying blaKPC Collected in U.S. Hospitals from 2012 to 2015.
    Antimicrob Agents Chemother. 2017;61.
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  835. ZABORSKYTE G, Andersen JB, Kragh KN, Ciofu O, et al
    Real-Time Monitoring of nfxB Mutant Occurrence and Dynamics in Pseudomonas aeruginosa Biofilm Exposed to Subinhibitory Concentrations of Ciprofloxacin.
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  836. VARGHESE FS, Rausalu K, Hakanen M, Saul S, et al
    Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments.
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  837. KONG LH, Lei CW, Ma SZ, Jiang W, et al
    Various Sequence Types of Escherichia coli Isolates Coharboring blaNDM-5 and mcr-1 Genes from a Commercial Swine Farm in China.
    Antimicrob Agents Chemother. 2017;61.
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  838. CASTON JJ, De la Torre A, Ruiz-Camps I, Sorli ML, et al
    Salvage Therapy with Ceftolozane-Tazobactam for Multidrug-Resistant Pseudomonas aeruginosa Infections.
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  839. LENHARD JR, Smith NM, Bulman ZP, Tao X, et al
    High-Dose Ampicillin-Sulbactam Combinations Combat Polymyxin-Resistant Acinetobacter baumannii in a Hollow-Fiber Infection Model.
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  840. THADEN JT, Li Y, Ruffin F, Maskarinec SA, et al
    Increased Costs Associated with Bloodstream Infections Caused by Multidrug-Resistant Gram-Negative Bacteria Are Due Primarily to Patients with Hospital-Acquired Infections.
    Antimicrob Agents Chemother. 2017;61.
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  841. JONES CL, Singh SS, Alamneh Y, Casella LG, et al
    In Vivo Fitness Adaptations of Colistin-Resistant Acinetobacter baumannii Isolates to Oxidative Stress.
    Antimicrob Agents Chemother. 2017;61.
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  842. BAKER KR, Sigurethardottir HH, Jana B, Guardabassi L, et al
    Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of beta-Lactamase-Producing Escherichia coli.
    Antimicrob Agents Chemother. 2017;61.
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  843. FARRELL DJ, Sader HS, Rhomberg PR, Scangarella-Oman NE, et al
    In Vitro Activity of Gepotidacin (GSK2140944) against Neisseria gonorrhoeae.
    Antimicrob Agents Chemother. 2017;61.
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  844. PFALLER MA, Messer SA, Rhomberg PR, Castanheira M, et al
    Activity of a Long-Acting Echinocandin (CD101) and Seven Comparator Antifungal Agents Tested against a Global Collection of Contemporary Invasive Fungal Isolates in the SENTRY 2014 Antifungal Surveillance Program.
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  845. PAPAGIANNITSIS CC, Tzouvelekis LS, Tzelepi E, Miriagou V, et al
    attI1-Located Small Open Reading Frames ORF-17 and ORF-11 in a Class 1 Integron Affect Expression of a Gene Cassette Possessing a Canonical Shine-Dalgarno Sequence.
    Antimicrob Agents Chemother. 2017;61.
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  846. GERITS E, Defraine V, Vandamme K, De Cremer K, et al
    Repurposing Toremifene for Treatment of Oral Bacterial Infections.
    Antimicrob Agents Chemother. 2017;61.
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  847. FREEMAN J, Pilling S, Vernon J, Wilcox MH, et al
    In Vitro Activities of MCB3681 and Eight Comparators against Clostridium difficile Isolates with Known Ribotypes and Diverse Geographical Spread.
    Antimicrob Agents Chemother. 2017;61.
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  848. WENDEL AF, Kaase M, Autenrieth IB, Peter S, et al
    Protracted Regional Dissemination of GIM-1-Producing Serratia marcescens in Western Germany.
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  849. ROBIN F, Beyrouthy R, Bonacorsi S, Aissa N, et al
    Inventory of Extended-Spectrum-beta-Lactamase-Producing Enterobacteriaceae in France as Assessed by a Multicenter Study.
    Antimicrob Agents Chemother. 2017;61.
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    February 2017
  850. GUZMAN PRIETO AM, Wijngaarden J, Braat JC, Rogers MR, et al
    The two component system ChtRS contributes to chlorhexidine tolerance in Enterococcus faecium.
    Antimicrob Agents Chemother. 2017 Feb 27. pii: AAC.02122.
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  851. DUDIUK C, Macedo D, Leonardelli F, Theill L, et al
    Molecular confirmation of the relationship between Candida guilliermondii Fks1p naturally occurring amino acid substitutions and its intrinsic reduced echinocandin susceptibility.
    Antimicrob Agents Chemother. 2017 Feb 27. pii: AAC.02644.
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  852. YANG F, Zhang L, Wakabayashi H, Myers J, et al
    Tolerance to caspofungin in Candida albicans is associated with at least three distinctive mechanisms that govern expression of FKS genes and cell wall remodeling.
    Antimicrob Agents Chemother. 2017 Feb 21. pii: AAC.00071.
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  853. ADAMS HM, Joyce LR, Guan Z, Akins RL, et al
    Streptococcus mitis and S. oralis lack a requirement for CdsA, the enzyme required for synthesis of major membrane phospholipids in bacteria.
    Antimicrob Agents Chemother. 2017 Feb 21. pii: AAC.02552.
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  854. KELLOGG SL, Little JL, Hoff JS, Kristich CJ, et al
    Requirement of the CroRS two-component system for resistance to cell-wall-targeting antimicrobials in Enterococcus faecium.
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  855. LARKIN E, Hager C, Chandra J, Mukherjee PK, et al
    The Emerging Candida auris: Characterization of Growth Phenotype, Virulence Factors, Antifungal Activity, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation.
    Antimicrob Agents Chemother. 2017 Feb 21. pii: AAC.02396.
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  856. LEPAK AJ, Zhao M, Marchillo K, VanHecker J, et al
    In vivo Pharmacodynamic Evaluation of Omadacycline (PTK 0796) against Streptococcus pneumoniae in the Murine Pneumonia Model.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.02368.
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  857. VAN DER LINDEN M, Otten J, Bergmann C, Latorre C, et al
    PBP2x in Streptococcus pseudopneumoniae - an insight into the diversity of PBP2x alleles and mutations in viridans streptococci.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.02646.
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  858. GLOUX K, Guillemet M, Soler C, Morvan C, et al
    Clinical relevance of FASII bypass in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.02515.
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  859. KANAMORI H, Parobek CM, Juliano JJ, van Duin D, et al
    A Prolonged Outbreak of KPC-3-Producing Enterobacter cloacae and Klebsiella pneumoniae Driven by Multiple Mechanisms of Resistance Transmission at a Large Academic Burn Center.
    Antimicrob Agents Chemother. 2017;61.
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  860. COLLINS SA, Kelso MJ, Rineh A, Yepuri NR, et al
    Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms.
    Antimicrob Agents Chemother. 2017;61.
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  861. JOHNSON TJ
    Carbapenemase-Producing Enterobacteriaceae in Swine Production in the United States: Impact and Opportunities.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Abstract available


  862. SULYOK KM, Kreizinger Z, Wehmann E, Lysnyansky I, et al
    Mutations Associated with Decreased Susceptibility to Seven Antimicrobial Families in Field and Laboratory-Derived Mycoplasma bovis Strains.
    Antimicrob Agents Chemother. 2017;61.
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  863. ZHAO F, Feng Y, Lu X, McNally A, et al
    IncP Plasmid Carrying Colistin Resistance Gene mcr-1 in Klebsiella pneumoniae from Hospital Sewage.
    Antimicrob Agents Chemother. 2017;61.
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  864. LIU BT, Song FJ, Zou M, Hao ZH, et al
    Emergence of Colistin Resistance Gene mcr-1 in Cronobacter sakazakii Producing NDM-9 and in Escherichia coli from the Same Animal.
    Antimicrob Agents Chemother. 2017;61.
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  865. KAMATH D, Gregory ST, O'Connor M
    The Loop 2 Region of Ribosomal Protein uS5 Influences Spectinomycin Sensitivity, Translational Fidelity, and Ribosome Biogenesis.
    Antimicrob Agents Chemother. 2017;61.
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  866. CECCARELLI D, van Essen-Zandbergen A, Veldman KT, Tafro N, et al
    Chromosome-Based blaOXA-48-Like Variants in Shewanella Species Isolates from Food-Producing Animals, Fish, and the Aquatic Environment.
    Antimicrob Agents Chemother. 2017;61.
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  867. MEINERSMANN RJ, Ladely SR, Plumblee JR, Cook KL, et al
    Prevalence of mcr-1 in the Cecal Contents of Food Animals in the United States.
    Antimicrob Agents Chemother. 2017;61.
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  868. AGEEVETS V, Sopova J, Lazareva I, Malakhova M, et al
    Genetic Environment of the blaKPC-2 Gene in a Klebsiella pneumoniae Isolate That May Have Been Imported to Russia from Southeast Asia.
    Antimicrob Agents Chemother. 2017;61.
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  869. LEE SJ, Awji EG, Park NH, Park SC, et al
    Using In Vitro Dynamic Models To Evaluate Fluoroquinolone Activity against Emergence of Resistant Salmonella enterica Serovar Typhimurium.
    Antimicrob Agents Chemother. 2017;61.
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  870. HANCOCK SJ, Phan MD, Peters KM, Forde BM, et al
    Identification of IncA/C Plasmid Replication and Maintenance Genes and Development of a Plasmid Multilocus Sequence Typing Scheme.
    Antimicrob Agents Chemother. 2017;61.
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  871. BROWN-ELLIOTT BA, Philley JV, Griffith DE, Thakkar F, et al
    In Vitro Susceptibility Testing of Bedaquiline against Mycobacterium avium Complex.
    Antimicrob Agents Chemother. 2017;61.
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  872. GIRLICH D, Bonnin RA, Bogaerts P, De Laveleye M, et al
    Chromosomal Amplification of the blaOXA-58 Carbapenemase Gene in a Proteus mirabilis Clinical Isolate.
    Antimicrob Agents Chemother. 2017;61.
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    January 2017
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    Effects of tedizolid phosphate on survival outcomes and suppression of production of staphylococcal toxins in a rabbit model of MRSA necrotizing pneumonia.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02734.
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  874. AJILEYE A, Alvarez N, Merker M, Walker TM, et al
    Some synonymous and non-synonymous gyrA mutations in Mycobacterium tuberculosis lead to systematic false-resistance results to fluoroquinolones with the Hain GenoType MTBDRsl assays.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02169.
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  875. GELDART K, Kaznessis YN
    Characterization of Class IIa Bacteriocin Resistance in Enterococcus faecium.
    Antimicrob Agents Chemother. 2017 Jan 23. pii: AAC.02033.
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  876. MELETIADIS J, Curfs-Breuker I, Meis JF, Mouton JW, et al
    In vitro antifungal susceptibility testing of Candida isolates with the EUCAST methodology.
    Antimicrob Agents Chemother. 2017 Jan 23. pii: AAC.02372.
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  877. MISHRA NN, Tran TT, Seepersaud R, Garcia-de-la-Maria C, et al
    Perturbations of Phosphatidate Cytidylyltransferase (CdsA) Mediate Daptomycin Resistance in Streptococcus mitis by a Novel Mechanism.
    Antimicrob Agents Chemother. 2017 Jan 23. pii: AAC.02435.
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  878. WANG X, Davlieva M, Reyes J, Panesso D, et al
    A Novel Phosphodiesterase of the GdpP Family Modulates Cyclic di-AMP Levels in Response to Cell Membrane Stress in Daptomycin-Resistant Enterococci.
    Antimicrob Agents Chemother. 2017 Jan 9. pii: AAC.01422.
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  879. KAWANISHI M, Abo H, Ozawa M, Uchiyama M, et al
    Prevalence of Colistin Resistance Gene mcr-1 and Absence of mcr-2 in Escherichia coli Isolated from Healthy Food-Producing Animals in Japan.
    Antimicrob Agents Chemother. 2016;61.
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  880. LIN D, Xie M, Li R, Chen K, et al
    IncFII Conjugative Plasmid-Mediated Transmission of blaNDM-1 Elements among Animal-Borne Escherichia coli Strains.
    Antimicrob Agents Chemother. 2016;61.
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  881. SHEN Z, Ding B, Bi Y, Wu S, et al
    CTX-M-190, a Novel beta-Lactamase Resistant to Tazobactam and Sulbactam, Identified in an Escherichia coli Clinical Isolate.
    Antimicrob Agents Chemother. 2016;61.
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  882. GISLASON AS, Choy M, Bloodworth RA, Qu W, et al
    Competitive Growth Enhances Conditional Growth Mutant Sensitivity to Antibiotics and Exposes a Two-Component System as an Emerging Antibacterial Target in Burkholderia cenocepacia.
    Antimicrob Agents Chemother. 2016;61.
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  883. NIE B, Long T, Ao H, Zhou J, et al
    Covalent Immobilization of Enoxacin onto Titanium Implant Surfaces for Inhibiting Multiple Bacterial Species Infection and In Vivo Methicillin-Resistant Staphylococcus aureus Infection Prophylaxis.
    Antimicrob Agents Chemother. 2016;61.
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  884. WAND ME, Bock LJ, Bonney LC, Sutton JM, et al
    Mechanisms of Increased Resistance to Chlorhexidine and Cross-Resistance to Colistin following Exposure of Klebsiella pneumoniae Clinical Isolates to Chlorhexidine.
    Antimicrob Agents Chemother. 2016;61.
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  885. SIME FB, Johnson A, Whalley S, Santoyo-Castelazo A, et al
    Pharmacodynamics of Aerosolized Fosfomycin and Amikacin against Resistant Clinical Isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a Hollow-Fiber Infection Model: Experimental Basis for Combination Therapy.
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  886. RENZONI A, Kelley WL, Rosato RR, Martinez MP, et al
    Molecular Bases Determining Daptomycin Resistance-Mediated Resensitization to beta-Lactams (Seesaw Effect) in Methicillin-Resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2016;61.
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  887. MOURAND G, Paboeuf F, Fleury MA, Jouy E, et al
    Escherichia coli Probiotic Strain ED1a in Pigs Has a Limited Impact on the Gut Carriage of Extended-Spectrum-beta-Lactamase-Producing E. coli.
    Antimicrob Agents Chemother. 2016;61.
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    December 2016
  888. GROSSMAN NT, Casadevall A
    Physiological Differences in C. neoformans in vitro versus in vivo and Their Effects on Antifungal Susceptibility.
    Antimicrob Agents Chemother. 2016 Dec 28. pii: AAC.02108.
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  889. FOFANA MO, Shrestha S, Knight GM, Cohen T, et al
    Role of pyrazinamide in the emergence of extensively drug-resistant tuberculosis: a multi-strain mathematical model.
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  890. SCHELL WA, Jones AM, Garvey EP, Hoekstra WJ, et al
    Fungal CYP51 Inhibitors VT-1161 and VT-1129 exhibit strong in vitro activity against Candida glabrata and C. krusei isolates clinically resistant to azole and echinocandin antifungal compounds.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.01817.
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  891. SONG KH, Kim M, Kim CJ, Cho JE, et al
    Impact of Vancomycin Minimum Inhibitory Concentration on Treatment Outcomes in Invasive Staphylococcus aureus Infections.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.01845.
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  892. PANG Y, Zhang Z, Wang Y, Wang S, et al
    Genotyping and prevalence of pyrazinamide- and moxifloxacin-resistant tuberculosis in China, 2000-2010: findings from the national survey data.
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  893. ZENG W, Bai Y, Wang M, Wang Z, et al
    Significant Divergence in Sensitivity to Antimalarial Drugs between Neighboring Plasmodium falciparum Populations along the Eastern Border of Myanmar.
    Antimicrob Agents Chemother. 2016 Dec 5. pii: AAC.01689.
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    November 2016
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    Molecular investigation of resistance to second line injectable drugs in multidrug-resistant clinical isolates of Mycobacterium tuberculosis in France.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01299.
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  895. SEBASTIAN J, Swaminath S, Nair RR, Jakkala K, et al
    De Novo Emergence of Genetically Resistant Mutants of Mycobacterium tuberculosis from the Persistence Phase Cells formed against Antituberculosis Drugs In Vitro.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01343.
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  896. PENROSE KJ, Wallis CL, Brumme CJ, Hamanishi KA, et al
    Frequent Cross-Resistance to Dapivirine in HIV-1 Subtype C-Infected Individuals on Failing First-Line Antiretroviral Therapy in South Africa.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01805.
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  897. BORDALLO-CARDONA MA, Escribano P, Gomez G de la Pedrosa E, Marcos-Zambrano LJ, et al
    In vitro exposure to increasing micafungin concentrations easily promotes echinocandin resistance in Candida glabrata isolates.
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  898. PRIGENT G, Ait-Ammar N, Levesque E, Fekkar A, et al
    Echinocandin resistance in Candida spp. isolated from liver transplant recipients.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01229.
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  899. SINGH M, Matsuo M, Sasaki T, Morimoto Y, et al
    In Vitro Tolerance of A Drug-Naive Staphylococcus aureus FDA209P towards Vancomycin.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01154.
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  900. RUDRAMURTHY SM, Seyedmousavi S, Dhaliwal M, Chakrabarti A, et al
    Pharmacodynamics of voriconazole against wild-type and azole-resistant Aspergillus flavus isolates in a non-neutropenic murine model of disseminated aspergillosis.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01491.
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  901. REIS DE SA LF, Toledo FT, Goncalves AC, Sousa BA, et al
    Synthetic organotellurium compounds sensitize drug resistant Candida albicans clinical isolates to fluconazole.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01231.
    PubMed     Abstract available


    October 2016
  902. WEI X, Chen P, Gao R, Li Y, et al
    Screening and characterization of the non-cyp51A mutation Afcox10 conferring azole resistance in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.02101.
    PubMed     Abstract available


  903. STRAUSS C, Hu Y, Coates A, Perreten V, et al
    A novel erm(44) gene variant from a human Staphylococcus saprophyticus confers resistance to macrolides, lincosamides but not streptogramins.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01655.
    PubMed     Abstract available


  904. ESPINEL-INGROFF A, Arendrup M, Canton E, Cordoba S, et al
    A multi-center study of method-dependent epidemiological cutoff values (ECVs) for resistance detection in Candida spp. and Aspergillus spp. to amphotericin B and echinocandins for the Etest agar diffusion method.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01792.
    PubMed     Abstract available


  905. FAKHIM H, Emami S, Vaezi A, Hashemi SM, et al
    In Vitro Activities of Novel Azole Compounds (ATTAF-1 and ATTAF-2) Against Fluconazole-Susceptible and -Resistant Isolates of Candida species.
    Antimicrob Agents Chemother. 2016 Oct 24. pii: AAC.01106.
    PubMed     Abstract available


  906. SUWUNNAKORN S, Wakabayashi H, Rustchenko E
    Chromosome 5 of human pathogen Candida albicans carries multiple genes for negative control of caspofungin and anidulafungin susceptibility.
    Antimicrob Agents Chemother. 2016 Oct 10. pii: AAC.01888.
    PubMed     Abstract available


  907. HAYS C, Louis M, Plainvert C, Dmytruk N, et al
    Changing epidemiology of Group B Streptococcus susceptibility to fluoroquinolones and aminoglycosides in France.
    Antimicrob Agents Chemother. 2016 Oct 10. pii: AAC.01374.
    PubMed     Abstract available


    September 2016
  908. LI Y, Wang Y, Zhang Z, Gao H, et al
    Association between embB Codon 306 Mutations, Phenotypic Resistance Profiles and Genotypic Characterization in Clinical Mycobacterium tuberculosis Isolates from Hebei, China.
    Antimicrob Agents Chemother. 2016 Sep 26. pii: AAC.00532.
    PubMed     Abstract available


  909. CUI L, Wang Y, Lv Y, Wang S, et al
    Nationwide Surveillance of Novel Oxazolidinone Resistance Gene optrA in Enterococcus spp. Isolates in China from 2004-2014.
    Antimicrob Agents Chemother. 2016 Sep 19. pii: AAC.01256.
    PubMed     Abstract available


  910. TSIANG M, Jones GS, Goldsmith J, Mulato A, et al
    Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile.
    Antimicrob Agents Chemother. 2016 Sep 19. pii: AAC.01474.
    PubMed     Abstract available


  911. AMANO M, Salcedo-Gomez PM, Zhao R, Yedidi RS, et al
    A Modified P1 Moiety Enhances in vitro Antiviral Activity against Various Multi-Drug-Resistant HIV-1 Variants and in vitro CNS Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413.
    Antimicrob Agents Chemother. 2016 Sep 12. pii: AAC.01428.
    PubMed     Abstract available


    August 2016
  912. ABASTABAR M, Rahimi N, Meis JF, Aslani N, et al
    Potent Activities of Novel Imidazoles (lanoconazole and luliconazole) Against a Collection of Azole Resistant and Susceptible Aspergillus fumigatus strains.
    Antimicrob Agents Chemother. 2016 Aug 29. pii: AAC.01193.
    PubMed     Abstract available


  913. ZHAO Y, Nagasaki Y, Kordalewska M, Press EG, et al
    Rapid detection of FKS-associated echinocandin resistance in Candida glabrata.
    Antimicrob Agents Chemother. 2016 Aug 22. pii: AAC.01574.
    PubMed     Abstract available


  914. DIEP BA, Le VT, Visram ZC, Rouha H, et al
    Improved protection in a rabbit model of CA-MRSA necrotizing pneumonia upon neutralization of leukocidins in addition to alpha-hemolysin.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01213.
    PubMed     Abstract available


  915. CHUANG YM, Dutta NK, Hung CF, Wu TC, et al
    The stringent response factors PPX1 and PPK2 play an important role in Mycobacterium tuberculosis metabolism, biofilm formation, and sensitivity to isoniazid in vivo.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01139.
    PubMed     Abstract available


  916. FOO CS, Lechartier B, Kolly GS, Boy-Rottger S, et al
    Characterization of DprE1-mediated benzothiazinone resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01523.
    PubMed     Abstract available


  917. NIKONENKO BV, Kornienko A, Majorov K, Ivanov P, et al
    In vitro activity of 3-triazenoindoles against Mycobacterium tuberculosis and Mycobacterium avium.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.00998.
    PubMed     Abstract available


  918. HO PL, Liu MC, Chow KH, Tse CW, et al
    Emergence of ileS2-carrying, multidrug-resistant plasmids in Staphylococcus lugdunensis.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.00948.
    PubMed     Abstract available


  919. PABST B, Pitts B, Lauchnor E, Stewart PS, et al
    Gel-entrapped Staphylococcus aureus as Models of Biofilm Infection Exhibit Growth in Dense Aggregates, Oxygen Limitation, Antibiotic Tolerance, and Heterogeneous Gene Expression.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.01336.
    PubMed     Abstract available


  920. GU W, Guo D, Zhang L, Xu D, et al
    Synergistic Effect of Azoles and Fluoxetine against Resistant Candida albicans Attributed to Attenuating Fungal Virulence.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.03046.
    PubMed     Abstract available


  921. WHALEY SG, Tsao S, Weber S, Zhang Q, et al
    The RTA3 gene, encoding a putative lipid translocase, influences the susceptibility of Candida albicans to fluconazole.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.00732.
    PubMed     Abstract available


  922. WAN TW, Hung WC, Tsai JC, Lin YT, et al
    Novel structure of Enterococcus faecium-originated ermB positive Tn1546-like in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.01096.
    PubMed     Abstract available


  923. LOCKE JB, Almaguer AL, Zuill DE, Bartizal K, et al
    Characterization of in vitro resistance development to the novel echinocandin, CD101, in Candida species.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.00620.
    PubMed     Abstract available


    July 2016
  924. HUANG K, Zhang Q, Song Y, Zhang Z, et al
    Characterization of spectinomycin resistance in Streptococcus suis: two novel insights into the drug-resistance formation and dissemination mechanism.
    Antimicrob Agents Chemother. 2016 Jul 25. pii: AAC.01157.
    PubMed     Abstract available


  925. MARTINEZ ZS, Castro E, Seong CS, Ceron MR, et al
    Fullerene Derivatives Strongly Inhibit HIV-1 Replication by Affecting Virus Maturation without Impairing Protease Activity.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.00341.
    PubMed     Abstract available


  926. CHEN Y, Lu Z, Zhao J, Zou Z, et al
    Epidemiology and Molecular Characterizations of Azole Resistance in Clinical and Environmental Aspergillus fumigatus from China.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.01005.
    PubMed     Abstract available


  927. BHATTACHARYA S, Sobel JD, White TC
    A Combination fluorescent assay demonstrates increased in Efflux Pump Activity as a resistance mechanism in Azole-Resistant Vaginal Candida albicans.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.01252.
    PubMed     Abstract available


  928. CHONG J, Quach C, Blanchard AC, Poliquin PG, et al
    Molecular epidemiology of vancomycin-intermediate heteroresistant Staphylococcus epidermidis outbreak in the neonatal intensive care unit.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00726.
    PubMed     Abstract available


  929. BURNHAM JP, Burnham CA, Warren DK, Kollef MH, et al
    IMPACT OF TIME TO APPROPRIATE THERAPY ON MORTALITY IN PATIENTS WITH VANCOMYCIN INTERMEDIATE STAPHYLOCOCCUS AUREUS INFECTION.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00925.
    PubMed     Abstract available


  930. JONES JC, Marathe BM, Lerner C, Kreis L, et al
    A novel endonuclease inhibitor exhibits broad-spectrum anti-influenza activity in vitro.
    Antimicrob Agents Chemother. 2016 Jul 5. pii: AAC.00888.
    PubMed     Abstract available


  931. LEONARDELLI F, Macedo D, Dudiuk C, Cabeza MS, et al
    Aspergillus fumigatus intrinsic fluconazole resistance is due to the naturally occurring T301I substitution in Cyp51Ap.
    Antimicrob Agents Chemother. 2016 Jul 5. pii: AAC.00905.
    PubMed     Abstract available


    May 2016
  932. LEPAK AJ, Andes DR
    In vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in the Murine Lung Infection Model.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.00647.
    PubMed     Abstract available


  933. CHIEN JY, Chien ST, Chiu WY, Yu CJ, et al
    Moxifloxacin Improves Treatment Outcomes in Patients with Ofloxacin-resistant Multidrug-resistant Tuberculosis.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.00425.
    PubMed     Abstract available


  934. BERGLUND B, Claesson C, Nilsson LE, Hanberger H, et al
    High prevalence of heterogeneously glycopeptide intermediate coagulase-negative staphylococci in sternal wounds.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.00217.
    PubMed     Abstract available


  935. CHEN H, Li C, Zemlicka J, Gentry BG, et al
    Potency and Stereoselectivity of Cyclopropavir Triphosphate Action on Human Cytomegalovirus DNA Polymerase.
    Antimicrob Agents Chemother. 2016 May 2. pii: AAC.00449.
    PubMed     Abstract available


  936. LINGARAJU S, Rigouts L, Gupta A, Lee J, et al
    Geographic differences in the contribution of ubiA mutations to high-level Ethambutol Resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 May 2. pii: AAC.03002.
    PubMed     Abstract available


    April 2016
  937. GEORGHIOU SB, Seifert M, Catanzaro D, Garfein RS, et al
    Frequency and Distribution of Tuberculosis Resistance-Associated Mutations between Mumbai, Moldova, and Eastern Cape.
    Antimicrob Agents Chemother. 2016 Apr 18. pii: AAC.00222.
    PubMed     Abstract available


  938. NOWICKA-SANS B, Protack T, Lin Z, Li Z, et al
    BMS-955176: Identification and Characterization of a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Anti-viral Spectrum and Gag Polymorphic Coverage.
    Antimicrob Agents Chemother. 2016 Apr 18. pii: AAC.02560.
    PubMed     Abstract available


  939. CHOU S, Ercolani RJ, Lanier ER
    Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected in Vitro that Confer Brincidofovir Resistance.
    Antimicrob Agents Chemother. 2016 Apr 4. pii: AAC.00214.
    PubMed     Abstract available


    March 2016
  940. MORADIGARAVAND D, Grandjean L, Martinez E, Li H, et al
    DfrA-thyA double deletion in para-aminosalicylic acid resistant Mycobacterium tuberculosis Beijing strains.
    Antimicrob Agents Chemother. 2016 Mar 28. pii: AAC.00253.
    PubMed     Abstract available


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