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Articles published in Metabolism

Retrieve available abstracts of 50 articles:
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Single Articles


    January 2026
  1. MUNOZ F, Gao Q, Mattanovich M, Trost K, et al
    Lysine potentiates insulin secretion via AASS-dependent catabolism and regulation of GABA content and signaling.
    Metabolism. 2026;174:156423.
    PubMed     Abstract available


    December 2025
  2. YANG J, Yang X, Zheng Y, Wang A, et al
    27-Hydroxycholesterol exacerbates hepatic insulin resistance via plasma membrane cholesterol remodeling.
    Metabolism. 2025;173:156392.
    PubMed     Abstract available


    November 2025
  3. JINYI L, Xianguang D, Yuhan D, Haoyue H, et al
    Metabolic reprogramming in diabetic foot ulcers: mechanisms, therapeutic implications and future perspectives.
    Metabolism. 2025;175:156455.
    PubMed     Abstract available


  4. WANG Y, Sandforth A, von Schwartzenberg RJ, Ganslmeier M, et al
    Lifestyle intervention is more effective in high 1-hour post-load glucose than in prediabetes for restoring beta-cell function, reducing ectopic fat, and preventing type 2 diabetes.
    Metabolism. 2025 Nov 3:156430. doi: 10.1016/j.metabol.2025.156430.
    PubMed     Abstract available


  5. STUBBENDORFF A, Janzi S, Jukkola J, Morency M, et al
    Mini-review of the EAT-Lancet planetary health diet and its role in cardiometabolic disease prevention.
    Metabolism. 2025;172:156373.
    PubMed     Abstract available


    October 2025
  6. PAN L, He Y, Xiang Y, Mao B, et al
    Angiopoietin-like protein 8 mediates inflammation and fibrosis of tubular cells in diabetic kidney disease progression by interacting with Akt2.
    Metabolism. 2025 Oct 17:156418. doi: 10.1016/j.metabol.2025.156418.
    PubMed     Abstract available


  7. ASHLAW EF, Elfers CT, Chichura KS, Miranda IC, et al
    A melanocortin 4- and glucagon-like peptide 1 receptor multiple agonist for the treatment of diabetes and obesity.
    Metabolism. 2025 Oct 13:156414. doi: 10.1016/j.metabol.2025.156414.
    PubMed     Abstract available


  8. MISHRA RC, Mallat RK, John CM, Belke D, et al
    Administration of the K(Ca) channel activator SKA-31 improves long-term endothelial function, blood pressure regulation and cardiac performance in rats with type 2 diabetes.
    Metabolism. 2025 Oct 1:156410. doi: 10.1016/j.metabol.2025.156410.
    PubMed     Abstract available


    August 2025
  9. HENDLINGER M, Mastrototaro L, Exterkate M, Apostolopoulou M, et al
    Exercise training increases skeletal muscle sphingomyelinases and affects mitochondrial quality control in men with type 2 diabetes.
    Metabolism. 2025 Aug 2:156361. doi: 10.1016/j.metabol.2025.156361.
    PubMed     Abstract available


  10. HAKIM JP, Handelsman Y, Banerjee T
    Use of finerenone in patients with chronic kidney disease at high risk of heart failure.
    Metabolism. 2025;169:156297.
    PubMed     Abstract available


  11. HUANG H, Ruan H, Lu X, Chen S, et al
    Comprehensive assessment of the causal effects and metabolite mediators of glucose-lowering drug targets on cardio-renal-liver-metabolic health.
    Metabolism. 2025;169:156276.
    PubMed     Abstract available


    July 2025
  12. LIANG T, Jiang T, Liang Z, Chen Y, et al
    Lactiplantibacillus plantarum strain 84-3-derived l-glutamine ameliorates glucose homeostasis via AMPK/PPARgamma signaling pathway activation in type 2 diabetes.
    Metabolism. 2025;172:156357.
    PubMed     Abstract available


  13. ZHANG H, Wang W, Liu P, Zhang T, et al
    Flot2 protects against podocyte injury by maintaining the stability of synaptopodin in diabetic nephropathy.
    Metabolism. 2025;171:156354.
    PubMed     Abstract available


  14. GUO C, Li J, Yang X, Xie W, et al
    AEBP1 as a promising therapeutic target for skeletal muscle insulin resistance in type 2 diabetes mellitus: Convergent evidence from Mendelian randomization and functional validation.
    Metabolism. 2025 Jul 4:156339. doi: 10.1016/j.metabol.2025.156339.
    PubMed     Abstract available


    June 2025
  15. SU JB, Chen G, Sun QY, Fu X, et al
    USP48 protects against myocardial ischemia-reperfusion injury by stabilizing and upregulating CNN1 in type 1 diabetes mice.
    Metabolism. 2025;170:156326.
    PubMed     Abstract available


    May 2025
  16. GALAN A, Garcia-Garcia F
    Revisiting gender differences in obesity and type 2 diabetes: Response letter.
    Metabolism. 2025 May 29:156307. doi: 10.1016/j.metabol.2025.156307.
    PubMed    


  17. WANG P, Zhang Y, Giovannucci EL
    Dietary context in the association between red meat consumption and risk of type 2 diabetes.
    Metabolism. 2025;169:156277.
    PubMed     Abstract available


    April 2025
  18. WU H, Yang Z, Zhou T, Wang J, et al
    UBC9 ameliorates diabetic cardiomyopathy by modulating cardiomyocyte mitophagy through NEDD4/RUNX2/PSEN2 axis.
    Metabolism. 2025 Apr 8:156264. doi: 10.1016/j.metabol.2025.156264.
    PubMed     Abstract available


  19. ZHONG Y, Wei J, Jiang R
    Revisiting gender differences in obesity and type 2 diabetes: Letter to the editor.
    Metabolism. 2025 Apr 3:156260. doi: 10.1016/j.metabol.2025.156260.
    PubMed    


    March 2025
  20. MOLDOVAN RA, Hidalgo MR, Castane H, Jimenez-Franco A, et al
    Landscape of sex differences in obesity and type 2 diabetes in subcutaneous adipose tissue: a systematic review and meta-analysis of transcriptomics studies.
    Metabolism. 2025 Mar 27:156241. doi: 10.1016/j.metabol.2025.156241.
    PubMed     Abstract available


  21. BHOWMICK DC, Ahn M, Bhattacharya S, Aslamy A, et al
    DOC2b enrichment mitigates proinflammatory cytokine-induced CXCL10 expression by attenuating IKKbeta and STAT-1 signaling in human islets.
    Metabolism. 2025;164:156132.
    PubMed     Abstract available


  22. KARAKASIS P, Patoulias D, Fragakis N, Mantzoros CS, et al
    Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition: Systematic review and network meta-analysis.
    Metabolism. 2025;164:156113.
    PubMed     Abstract available


    February 2025
  23. SCHORK A, Fritsche A, Schleicher ED, Peter A, et al
    Differential risk assessment in persons at risk of type 2 diabetes using urinary peptidomics.
    Metabolism. 2025;167:156174.
    PubMed     Abstract available


  24. HUANG J
    A systematic review & updated meta-analysis on the association between higher consumption of ultra processed foods and risk of diabetes and its complications: Letter to the editor.
    Metabolism. 2025 Feb 11:156156. doi: 10.1016/j.metabol.2025.156156.
    PubMed    


  25. SOUZA M, Moura FS, Lima LCV, Amaral MJM, et al
    A systematic review & updated meta-analysis on the association between higher consumption of ultra processed foods and risk of diabetes and its complications: Response letter.
    Metabolism. 2025 Feb 11:156155. doi: 10.1016/j.metabol.2025.156155.
    PubMed    


  26. CHEN J, Luo M, Xing Z, Chen Y, et al
    Start small, think big: MicroRNAs in diabetes mellitus and relevant cardiorenal-liver metabolic health spectrum.
    Metabolism. 2025 Feb 4:156153. doi: 10.1016/j.metabol.2025.156153.
    PubMed     Abstract available


  27. MEZZA T, Wewer Albrechtsen NJ, Di Giuseppe G, Ferraro PM, et al
    Human subjects with impaired beta-cell function and glucose tolerance have higher levels of intra-islet intact GLP-1.
    Metabolism. 2025;163:156087.
    PubMed     Abstract available


  28. KOKKORAKIS M, Folkertsma P, Forte JC, Wolffenbuttel BHR, et al
    GDF-15 improves the predictive capacity of steatotic liver disease non-invasive tests for incident morbidity and mortality risk for cardio-renal-metabolic diseases and malignancies.
    Metabolism. 2025;163:156047.
    PubMed     Abstract available


    January 2025
  29. SOUZA M, Moura FS, Lima LCV, Amaral MJM, et al
    Association between higher consumption of ultra-processed foods and risk of diabetes and its complications: A systematic review & updated meta-analysis.
    Metabolism. 2025 Jan 21:156134. doi: 10.1016/j.metabol.2025.156134.
    PubMed     Abstract available


  30. LUO YY, Ruan CS, Zhao FZ, Yang M, et al
    ZBED3 exacerbates hyperglycemia by promoting hepatic gluconeogenesis through CREB signaling.
    Metabolism. 2025;162:156049.
    PubMed     Abstract available


  31. DENG X, Tang C, Fang T, Li T, et al
    Disruption of branched-chain amino acid homeostasis promotes the progression of DKD via enhancing inflammation and fibrosis-associated epithelial-mesenchymal transition.
    Metabolism. 2025;162:156037.
    PubMed     Abstract available


    December 2024
  32. DOU C, Liu D, Kong L, Chen M, et al
    Shared genetic architecture of type 2 diabetes with muscle mass and function and frailty reveals comorbidity etiology and pleiotropic druggable targets.
    Metabolism. 2024 Dec 20:156112. doi: 10.1016/j.metabol.2024.156112.
    PubMed     Abstract available


  33. KIM JS, Jun JH, Lee J, Park S, et al
    HDAC6 mediates NLRP3 inflammasome activation in the pathogenesis of diabetic retinopathy.
    Metabolism. 2024 Dec 15:156108. doi: 10.1016/j.metabol.2024.156108.
    PubMed     Abstract available


    November 2024
  34. WU Q, Zeng Y, Geng K, Guo M, et al
    The role of IL-1 family cytokines in diabetic cardiomyopathy.
    Metabolism. 2024 Nov 25:156083. doi: 10.1016/j.metabol.2024.156083.
    PubMed     Abstract available


  35. CONGUR I, Mingrone G, Guan K
    Targeting endoplasmic reticulum stress as a potential therapeutic strategy for diabetic cardiomyopathy.
    Metabolism. 2024 Nov 6:156062. doi: 10.1016/j.metabol.2024.156062.
    PubMed     Abstract available


  36. ZHANG H, Zhou XD, Shapiro MD, Lip GYH, et al
    Global burden of metabolic diseases, 1990-2021.
    Metabolism. 2024;160:155999.
    PubMed     Abstract available


    August 2024
  37. MISHRA RC, Belke DD, Singh L, Wulff H, et al
    Targeting endothelial K(Ca) channels in vivo restores arterial and endothelial function in type 2 diabetic rats.
    Metabolism. 2024 Aug 18:156001. doi: 10.1016/j.metabol.2024.156001.
    PubMed     Abstract available


  38. ROSELL-DIAZ M, Petit-Gay A, Molas-Prat C, Gallardo-Nuell L, et al
    Metformin-induced changes in the gut microbiome and plasma metabolome are associated with cognition in men.
    Metabolism. 2024;157:155941.
    PubMed     Abstract available


  39. CAI Z, Yang Y, Zhong J, Ji Y, et al
    cGAS suppresses beta-cell proliferation by a STING-independent but CEBPbeta-dependent mechanism.
    Metabolism. 2024;157:155933.
    PubMed     Abstract available


    July 2024
  40. KANG JS, Cho NJ, Lee SW, Lee JG, et al
    RIPK3 causes mitochondrial dysfunction and albuminuria in diabetic podocytopathy through PGAM5-Drp1 signaling.
    Metabolism. 2024 Jul 30:155982. doi: 10.1016/j.metabol.2024.155982.
    PubMed     Abstract available


  41. SHU S, Cui H, Liu Z, Zhang H, et al
    Suppression of RCAN1 alleviated lipid accumulation and mitochondrial fission in diabetic cardiomyopathy.
    Metabolism. 2024 Jul 23:155977. doi: 10.1016/j.metabol.2024.155977.
    PubMed     Abstract available


  42. ZHAO M, Shen Z, Zheng Z, Xu Y, et al
    Cardiomyocyte LGR6 alleviates ferroptosis in diabetic cardiomyopathy via regulating mitochondrial biogenesis.
    Metabolism. 2024 Jul 20:155979. doi: 10.1016/j.metabol.2024.155979.
    PubMed     Abstract available


  43. RICHTER MM, Kemp IM, Heeboll S, Winther-Sorensen M, et al
    Glucagon augments the secretion of FGF21 and GDF15 in MASLD by indirect mechanisms.
    Metabolism. 2024;156:155915.
    PubMed     Abstract available


    June 2024
  44. HANDELSMAN Y, Anderson JE, Bakris GL, Ballantyne CM, et al
    DCRM 2.0: Multispecialty practice recommendations for the management of diabetes, cardiorenal, and metabolic diseases.
    Metabolism. 2024 Jun 4:155931. doi: 10.1016/j.metabol.2024.155931.
    PubMed     Abstract available


  45. SABATINI S, Nolan JJ, O'Donoghue G, Kennedy A, et al
    Baseline phenotypes with preserved beta-cell function and high insulin concentrations have the best improvements in glucose tolerance after weight loss: results from the prospective DEXLIFE and EGIR-RISC studies.
    Metabolism. 2024;155:155910.
    PubMed     Abstract available


    May 2024
  46. HUTTASCH M, Roden M, Kahl S
    Obesity and MASLD: Is weight loss the (only) key to treat metabolic liver disease?
    Metabolism. 2024 May 21:155937. doi: 10.1016/j.metabol.2024.155937.
    PubMed     Abstract available


  47. LIAN LY, Targher G, Byrne CD, Liu WY, et al
    Resmetirom for MASH patients with diabetes: challenges and opportunities in the real world.
    Metabolism. 2024 May 15:155935. doi: 10.1016/j.metabol.2024.155935.
    PubMed    


    April 2024
  48. JEREMIAH SS, Moin ASM, Butler AE
    Virus-induced diabetes mellitus, revisiting infection etiology in light of SARS-CoV-2.
    Metabolism. 2024 Apr 18:155917. doi: 10.1016/j.metabol.2024.155917.
    PubMed     Abstract available


  49. ROSENDO-SILVA D, Gomes PB, Rodrigues T, Viana S, et al
    Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction.
    Metabolism. 2024;153:155788.
    PubMed     Abstract available


    March 2024
  50. HE Y, Qu L
    The role and mechanisms of non-coding RNAs in diabetic peripheral neuropathy.
    Metabolism. 2024 Mar 8:155833. doi: 10.1016/j.metabol.2024.155833.
    PubMed     Abstract available


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