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Diabetes

Free Subscription Articles published in Lancet Retrieve available abstracts of 48 articles: HTML format

Single Articles

November 2025
1. HORN DB, Ryan DH, Kis SG, Alves B, et al
   Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial.
   Lancet. 2025 Nov 20:S0140-6736(25)02165-8. doi: 10.1016/S0140-6736(25)02165.
   PubMed     Abstract available
   
   
   
2. ROEP BO
   Personalised prevention therapy in type 1 diabetes.
   Lancet. 2025 Nov 11:S0140-6736(25)02005-7. doi: 10.1016/S0140-6736(25)02005.
   PubMed    
   
   
   
3. ZIEGLER AG, Achenbach P, Weiss A, Berner R, et al
   Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): a European, randomised, placebo-controlled, primary prevention trial.
   Lancet. 2025 Nov 11:S0140-6736(25)01726-X. doi: 10.1016/S0140-6736(25)01726.
   PubMed     Abstract available
   
   
   
4. HEERSPINK HJL, Cardona JF, Jolly S, Pergola PE, et al
   Balcinrenone in combination with dapagliflozin compared with dapagliflozin alone in patients with chronic kidney disease and albuminuria: a randomised, active-controlled double-blind, phase 2b clinical trial.
   Lancet. 2025 Nov 8:S0140-6736(25)02014-8. doi: 10.1016/S0140-6736(25)02014.
   PubMed     Abstract available
   
   
   September 2025
5. ZIEGLER AG, Cengiz E, Kay TWH
   The future of type 1 diabetes therapy.
   Lancet. 2025 Sep 19:S0140-6736(25)01438-2. doi: 10.1016/S0140-6736(25)01438.
   PubMed     Abstract available
   
   
   
6. ISGANAITIS E, Laffel LM
   Dual incretin agonist for paediatric type 2 diabetes: an eagerly awaited opportunity.
   Lancet. 2025 Sep 19:S0140-6736(25)01908-7. doi: 10.1016/S0140-6736(25)01908.
   PubMed    
   
   
   
7. SPEAKE C
   ATG as disease-modifying therapy for new-onset type 1 diabetes.
   Lancet. 2025 Sep 18:S0140-6736(25)01773-8. doi: 10.1016/S0140-6736(25)01773.
   PubMed    
   
   
   
8. MATHIEU C, Wych J, Hendriks AEJ, Van Ryckeghem L, et al
   Minimum effective low dose of antithymocyte globulin in people aged 5-25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial.
   Lancet. 2025 Sep 18:S0140-6736(25)01674-5. doi: 10.1016/S0140-6736(25)01674.
   PubMed     Abstract available
   
   
   
9. HANNON TS, Chao LC, Barrientos-Perez M, Pamidipati KC, et al
   Efficacy and safety of tirzepatide in children and adolescents with type 2 diabetes (SURPASS-PEDS): a randomised, double-blind, placebo-controlled, phase 3 trial.
   Lancet. 2025 Sep 17:S0140-6736(25)01774-X. doi: 10.1016/S0140-6736(25)01774.
   PubMed     Abstract available
   
   
   July 2025
10. ZHOU B, Gregg EW, Danaei G, Ezzati M, et al
    Worldwide trends in diabetes prevalence: the NCD-RisC study - Authors' reply.
    Lancet. 2025;406:133-134.
    PubMed    
    
    
    
11. LIPSCOMBE L, Dasgupta K, Shah B
    Worldwide trends in diabetes prevalence: the NCD-RisC study.
    Lancet. 2025;406:132-133.
    PubMed    
    
    
    
12. BOYKO EJ, Ong KL, Duncan BB
    Worldwide trends in diabetes prevalence: the NCD-RisC study.
    Lancet. 2025;406:131-132.
    PubMed    
    
    
    
13. RUSSELL-JONES D, Klonoff DC
    Use of once-weekly insulins for type 1 diabetes.
    Lancet. 2025;406:130.
    PubMed    
    
    
    
14. LOVE KM, Kinlaw AC, Brown SA
    Use of once-weekly insulins for type 1 diabetes - Author's reply.
    Lancet. 2025;406:130-131.
    PubMed    
    
    
    
15. GASIOREK A, Heydorn A, Gabery S, Hjerpsted JB, et al
    Safety, tolerability, pharmacokinetics, and pharmacodynamics of the first-in-class GLP-1 and amylin receptor agonist, amycretin: a first-in-human, phase 1, double-blind, randomised, placebo-controlled trial.
    Lancet. 2025;406:135-148.
    PubMed     Abstract available
    
    
    June 2025
16. MISRA S, Khunti K, Goyal A, Gable D, et al
    Managing early-onset type 2 diabetes in the individual and at the population level.
    Lancet. 2025 Jun 20:S0140-6736(25)01067-0. doi: 10.1016/S0140-6736(25)01067.
    PubMed     Abstract available
    
    
    
17. LIM LL, Jones S, Cikomola JC, Hivert MF, et al
    Understanding the drivers and consequences of early-onset type 2 diabetes.
    Lancet. 2025 Jun 20:S0140-6736(25)01012-8. doi: 10.1016/S0140-6736(25)01012.
    PubMed     Abstract available
    
    
    
18. LUK A, Wild SH, Jones S, Anjana RM, et al
    Early-onset type 2 diabetes: the next major diabetes transition.
    Lancet. 2025 Jun 20:S0140-6736(25)00830-X. doi: 10.1016/S0140-6736(25)00830.
    PubMed     Abstract available
    
    
    
19. THE LANCET
    Early-onset type 2 diabetes: no time for defeatism.
    Lancet. 2025 Jun 20:S0140-6736(25)01295-4. doi: 10.1016/S0140-6736(25)01295.
    PubMed    
    
    
    
20. BLEVINS T, Dahl D, Perez Manghi FC, Murthy S, et al
    Once-weekly insulin efsitora alfa versus once-daily insulin glargine U100 in adults with type 2 diabetes treated with basal and prandial insulin (QWINT-4): a phase 3, randomised, non-inferiority trial.
    Lancet. 2025 Jun 20:S0140-6736(25)01069-4. doi: 10.1016/S0140-6736(25)01069.
    PubMed     Abstract available
    
    
    
21. PHILIS-TSIMIKAS A, Bergenstal RM, Bailey TS, Jinnouchi H, et al
    Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 2 diabetes currently treated with basal insulin (QWINT-3): a phase 3, randomised, non-inferiority trial.
    Lancet. 2025 Jun 20:S0140-6736(25)01044-X. doi: 10.1016/S0140-6736(25)01044.
    PubMed     Abstract available
    
    
    
22. CHOW EW, Chow E
    Future of once-weekly insulins in type 2 diabetes: efficacy and safety.
    Lancet. 2025 Jun 20:S0140-6736(25)01098-0. doi: 10.1016/S0140-6736(25)01098.
    PubMed    
    
    
    May 2025
23. GARDOSI J, Ewington LJ, Booth K, Bick D, et al
    Induction of labour versus standard care to prevent shoulder dystocia in fetuses suspected to be large for gestational age in the UK (the Big Baby trial): a multicentre, open-label, randomised controlled trial.
    Lancet. 2025 May 1:S0140-6736(25)00162-X. doi: 10.1016/S0140-6736(25)00162.
    PubMed     Abstract available
    
    
    March 2025
24. BONACA MP, Catarig AM, Houlind K, Ludvik B, et al
    Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE): a phase 3b, double-blind, randomised, placebo-controlled trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00509-4. doi: 10.1016/S0140-6736(25)00509.
    PubMed     Abstract available
    
    
    
25. DENNIS JM, Young KG, Cardoso P, Gudemann LM, et al
    A five-drug class model using routinely available clinical features to optimise prescribing in type 2 diabetes: a prediction model development and validation study.
    Lancet. 2025;405:701-714.
    PubMed     Abstract available
    
    
    
26. SEIDU S, Ikhile D
    Personalised type 2 diabetes therapy in primary care.
    Lancet. 2025;405:672-674.
    PubMed    
    
    
    January 2025
27. ADLER AI, Coleman RL, Whiteley WN, Holman RR, et al
    The legacy effect of hyperglycaemia in type 2 diabetes - Authors' reply.
    Lancet. 2025;405:29.
    PubMed    
    
    
    
28. HOU R, Ren J
    The legacy effect of hyperglycaemia in type 2 diabetes.
    Lancet. 2025;405:28-29.
    PubMed    
    
    
    
29. PRATTICHIZZO F, Ceriello A
    The legacy effect of hyperglycaemia in type 2 diabetes.
    Lancet. 2025;405:28.
    PubMed    
    
    
    November 2024
30. 
    Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants.
    Lancet. 2024;404:2077-93.
    PubMed     Abstract available
    
    
    
31. GUARIGUATA L, Sobers N
    Rising diabetes, lagging treatment, and the need for better systems.
    Lancet. 2024 Nov 12:S0140-6736(24)02422-X. doi: 10.1016/S0140-6736(24)02422.
    PubMed    
    
    
    September 2024
32. LOVE KM, Brown SA
    The promise of once-weekly insulins for type 1 diabetes: update on progress.
    Lancet. 2024;404:1081-1083.
    PubMed    
    
    
    
33. BERGENSTAL RM, Weinstock RS, Mathieu C, Onishi Y, et al
    Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 1 diabetes (QWINT-5): a phase 3 randomised non-inferiority trial.
    Lancet. 2024;404:1132-1142.
    PubMed     Abstract available
    
    
    August 2024
34. KOSIBOROD MN, Deanfield J, Pratley R, Borlaug BA, et al
    Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials.
    Lancet. 2024 Aug 29:S0140-6736(24)01643-X. doi: 10.1016/S0140-6736(24)01643.
    PubMed     Abstract available
    
    
    
35. DELLGREN JL, Persad G, Emanuel EJ
    International coverage of GLP-1 receptor agonists: a review and ethical analysis of discordant approaches.
    Lancet. 2024 Aug 16:S0140-6736(24)01356-4. doi: 10.1016/S0140-6736(24)01356.
    PubMed    
    
    
    
36. MARECEK R, Kissling S, Teso AD, Vuignier Y, et al
    Chronic metabolic acidosis in a patient with diabetes on maintenance haemodialysis: mind the anion gap.
    Lancet. 2024;404:570-571.
    PubMed    
    
    
    July 2024
37. RODRIGUEZ-GUTIERREZ R
    Legacy effect of intensive glycaemic control in type 2 diabetes-the UKPDS.
    Lancet. 2024;404:100-102.
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38. SIMMONS D, Gupta Y, Hernandez TL, Levitt N, et al
    Call to action for a life course approach.
    Lancet. 2024;404:193-214.
    PubMed     Abstract available
    
    
    June 2024
39. LIU J, Li Y, Ge J, Yan X, et al
    Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label, blinded-outcome, randomised trial.
    Lancet. 2024 Jun 27:S0140-6736(24)01028-6. doi: 10.1016/S0140-6736(24)01028.
    PubMed     Abstract available
    
    
    
40. STRASSBURGER MATZENBACHER L, Alessi J, Telo GH
    Diabetes management amidst floods in Brazil.
    Lancet. 2024 Jun 26:S0140-6736(24)01177-2. doi: 10.1016/S0140-6736(24)01177.
    PubMed    
    
    
    
41. SWEETING A, Hannah W, Backman H, Catalano P, et al
    Epidemiology and management of gestational diabetes.
    Lancet. 2024 Jun 18:S0140-6736(24)00825-0. doi: 10.1016/S0140-6736(24)00825.
    PubMed     Abstract available
    
    
    
42. HIVERT MF, Backman H, Benhalima K, Catalano P, et al
    Pathophysiology from preconception, during pregnancy, and beyond.
    Lancet. 2024 Jun 18:S0140-6736(24)00827-4. doi: 10.1016/S0140-6736(24)00827.
    PubMed     Abstract available
    
    
    May 2024
43. JAFFAR S
    Integrated HIV, diabetes, and hypertension care in sub-Saharan Africa - Authors' reply.
    Lancet. 2024;403:2292.
    PubMed    
    
    
    
44. CAI S, Xu Z, Zhao Y, Zuhlke L, et al
    Integrated HIV, diabetes, and hypertension care in sub-Saharan Africa.
    Lancet. 2024;403:2291.
    PubMed    
    
    
    
45. HAVLIR D, Kamya MR, Petersen M
    Integrated HIV, diabetes, and hypertension care in sub-Saharan Africa.
    Lancet. 2024;403:2291-2292.
    PubMed    
    
    
    
46. ADLER AI, Coleman RL, Leal J, Whiteley WN, et al
    Post-trial monitoring of a randomised controlled trial of intensive glycaemic control in type 2 diabetes extended from 10 years to 24 years (UKPDS 91).
    Lancet. 2024 May 17:S0140-6736(24)00537-3. doi: 10.1016/S0140-6736(24)00537.
    PubMed     Abstract available
    
    
    March 2024
47. BROWN DM, Boyer DS, Do DV, Wykoff CC, et al
    Intravitreal aflibercept 8 mg in diabetic macular oedema (PHOTON): 48-week results from a randomised, double-masked, non-inferiority, phase 2/3 trial.
    Lancet. 2024 Mar 7:S0140-6736(23)02577-1. doi: 10.1016/S0140-6736(23)02577.
    PubMed     Abstract available
    
    
    
48. GABRIELLE PH, Creuzot-Garcher C
    Can high-dose aflibercept satisfy unmet treatment needs in diabetic macular oedema?
    Lancet. 2024 Mar 7:S0140-6736(23)02760-5. doi: 10.1016/S0140-6736(23)02760.
    PubMed    
    
    

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