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COVID-19: Daily Top 10 Papers


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Articles published in J Biol Chem

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    May 2021
  1. GE W, Zhao Y, Yang Y, Ding Z, et al
    An insulin-independent mechanism for transcriptional regulation of Foxo1 in type 2 diabetic mice.
    J Biol Chem. 2021 May 28:100846. doi: 10.1016/j.jbc.2021.100846.
    PubMed     Abstract available

  2. AMDARE N, Purcell AW, DiLorenzo TP
    Non-contiguous T cell epitopes in autoimmune diabetes: From mice to men and back again.
    J Biol Chem. 2021 May 24:100827. doi: 10.1016/j.jbc.2021.100827.
    PubMed     Abstract available

  3. YE J, Stefan-Lifshitz M, Tomer Y
    Genetic and environmental factors regulate the type 1 diabetes gene CTSH via differential DNA methylation.
    J Biol Chem. 2021 May 13:100774. doi: 10.1016/j.jbc.2021.100774.
    PubMed     Abstract available

  4. KOMENO M, Pang X, Shimizu A, Molla MR, et al
    Cardio- and reno-protective effects of dipeptidyl peptidase III in diabetic mice.
    J Biol Chem. 2021 May 7:100761. doi: 10.1016/j.jbc.2021.100761.
    PubMed     Abstract available

    April 2021
  5. CHEN Y, Hu W, Li Q, Zhao S, et al
    NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity.
    J Biol Chem. 2021 Apr 1:100624. doi: 10.1016/j.jbc.2021.100624.
    PubMed     Abstract available

    March 2021
  6. LOPEZ-SOLDADO I, Guinovart JJ, Duran J
    Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice.
    J Biol Chem. 2021 Mar 2:100498. doi: 10.1016/j.jbc.2021.100498.
    PubMed     Abstract available

    January 2021
  7. KLYUYEVA AV, Belyaeva OV, Goggans KR, Krezel W, et al
    Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes.
    J Biol Chem. 2021 Jan 21:100323. doi: 10.1016/j.jbc.2021.100323.
    PubMed     Abstract available

  8. JIANG Y, Luo W, Wang B, Yi Z, et al
    1alpha,25-Dihydroxyvitamin D3 ameliorates diabetes-induced bone loss by attenuating FoxO1-mediated autophagy.
    J Biol Chem. 2021 Jan 12:100287. doi: 10.1016/j.jbc.2021.100287.
    PubMed     Abstract available

    December 2020
  9. VAN DIERENDONCK XAMH, Sancerni T, Alves-Guerra MC, Stienstra R, et al
    The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance.
    J Biol Chem. 2020;295:17535-17548.
    PubMed     Abstract available

  10. COCHRANE VA, Wu Y, Yang Z, ElSheikh A, et al
    Leptin modulates pancreatic beta-cell membrane potential through Src kinase-mediated phosphorylation of NMDA receptors.
    J Biol Chem. 2020;295:17281-17297.
    PubMed     Abstract available

    November 2020
  11. SCHAID MD, Green CL, Peter DC, Gallagher SJ, et al
    Agonist-independent Galphaz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes.
    J Biol Chem. 2020 Nov 10. pii: RA120.015585. doi: 10.1074/jbc.RA120.015585.
    PubMed     Abstract available

  12. PARANDEH F, Amisten S, Verma G, Mohammed Al-Amily I, et al
    Inhibitory effect of UDP-glucose on cAMP generation and insulin secretion.
    J Biol Chem. 2020;295:15245-15252.
    PubMed     Abstract available

    October 2020
  13. SHAH AM, Wondisford FE
    Tracking the carbons supplying gluconeogenesis.
    J Biol Chem. 2020;295:14419-14429.
    PubMed     Abstract available

  14. PERRY RJ, Shulman GI
    Sodium-glucose cotransporter-2 inhibitors: Understanding the mechanisms for therapeutic promise and persisting risks.
    J Biol Chem. 2020;295:14379-14390.
    PubMed     Abstract available

  15. MAITY S, Das F, Kasinath BS, Ghosh-Choudhury N, et al
    TGFbeta acts through PDGFRbeta to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression.
    J Biol Chem. 2020;295:14262-14278.
    PubMed     Abstract available

    June 2020
  16. DUAN Y, Luo Q, Wang Y, Ma Y, et al
    Adipose mesenchymal stem cell-derived extracellular vesicles containing microRNA-26a-5p target TLR4 and protect against diabetic nephropathy.
    J Biol Chem. 2020 Jun 24. pii: RA120.012522. doi: 10.1074/jbc.RA120.012522.
    PubMed     Abstract available

    May 2020
  17. DIERSCKE SK, Toro AL, Miller WP, Sunilkumar S, et al
    Diabetes enhances translation of Cd40 mRNA in murine retinal Muller glia via a 4E-BP1/2-dependent mechanism.
    J Biol Chem. 2020 May 31. pii: RA120.013711. doi: 10.1074/jbc.RA120.013711.
    PubMed     Abstract available

  18. MILLER WP, Sunilkumar S, Giordano JF, Toro AL, et al
    The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation.
    J Biol Chem. 2020;295:7350-7361.
    PubMed     Abstract available

  19. MIYAMOTO S, Zhang G, Hall D, Oates PJ, et al
    Restoring mitochondrial superoxide levels with elamipretide (MTP-131) protects db/db mice against progression of diabetic kidney disease.
    J Biol Chem. 2020;295:7249-7260.
    PubMed     Abstract available

    April 2020
  20. ZHANG IX, Ren J, Vadrevu S, Raghavan M, et al
    ER stress increases store-operated Ca(2+) entry (SOCE) and augments basal insulin secretion in pancreatic beta cells.
    J Biol Chem. 2020;295:5685-5700.
    PubMed     Abstract available

  21. MILLER WP, Sunilkumar S, Giordano JF, Toro AL, et al
    The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation.
    J Biol Chem. 2020 Apr 15. pii: RA120.013093. doi: 10.1074/jbc.RA120.013093.
    PubMed     Abstract available

  22. MIYAMOTO S, Zhang G, Hall D, Oates PJ, et al
    Restoring mitochondrial superoxide levels with elamipretide (MTP-131) protects db/db mice against progression of diabetic kidney disease.
    J Biol Chem. 2020 Apr 10. pii: RA119.011110. doi: 10.1074/jbc.RA119.011110.
    PubMed     Abstract available

  23. ABBADI A, Loftis J, Wang A, Yu M, et al
    Heparin inhibits proinflammatory and promotes anti-inflammatory macrophage polarization under hyperglycemic stress.
    J Biol Chem. 2020;295:4849-4857.
    PubMed     Abstract available

  24. DIAZ-CORANGUEZ M, Lin CM, Liebner S, Antonetti DA, et al
    Norrin restores blood-retinal barrier properties after vascular endothelial growth factor-induced permeability.
    J Biol Chem. 2020;295:4647-4660.
    PubMed     Abstract available

    March 2020
  25. PANG H, Wang X, Zhao S, Xi W, et al
    Loss of the voltage-gated proton channel Hv1 decreases insulin secretion and leads to hyperglycemia and glucose intolerance in mice.
    J Biol Chem. 2020;295:3601-3613.
    PubMed     Abstract available

  26. REGE NK, Liu M, Dhayalan B, Chen YS, et al
    "Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolution.
    J Biol Chem. 2020;295:3080-3098.
    PubMed     Abstract available

    December 2019
  27. SIMON MC, Reinbeck AL, Wessel C, Heindirk J, et al
    Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in non-obese diabetic mice.
    J Biol Chem. 2019 Dec 10. pii: RA119.010816. doi: 10.1074/jbc.RA119.010816.
    PubMed     Abstract available

    October 2019
  28. OHNO RI, Ichimaru K, Tanaka S, Sugawa H, et al
    Glucoselysine is derived from fructose and accumulates in the eye lens of diabetic rats.
    J Biol Chem. 2019 Oct 8. pii: RA119.010744. doi: 10.1074/jbc.RA119.010744.
    PubMed     Abstract available

    September 2019
  29. NISHAD R, Mukhi D, Tahaseen SV, Mungamuri SK, et al
    Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy.
    J Biol Chem. 2019 Sep 11. pii: RA119.008966. doi: 10.1074/jbc.RA119.008966.
    PubMed     Abstract available

  30. ZOU MH, Kirkpatrick SS, Davis BJ, Nelson JS, et al
    Withdrawal: Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo : Role of mitochondrial reactive nitrogen species.
    J Biol Chem. 2019;294:13525.

    August 2019
    Cutting fuel offers new clues in diabetic mystery.
    J Biol Chem. 2019;294:12328-12329.
    PubMed     Abstract available

    July 2019
  32. JIA Y, Reddy MA, Das S, Oh HJ, et al
    Dysregulation of histone H3 lysine 27 trimethylation in transforming growth factor-beta1 induced gene expression in mesangial cells and diabetic kidney.
    J Biol Chem. 2019 Jul 2. pii: RA119.007575. doi: 10.1074/jbc.RA119.007575.
    PubMed     Abstract available

    June 2019
  33. SUN L, Pan X, Wada J, Haas CS, et al
    Withdrawal: Isolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy.
    J Biol Chem. 2019;294:10382.

  34. SUN L, Dutta RK, Xie P, Kanwar YS, et al
    Withdrawal: myo-Inositol oxygenase overexpression accentuates generation of reactive oxygen species and exacerbates cellular injury following high glucose ambience: A new mechanism relevant to the pathogenesis of diabetic nephropathy.
    J Biol Chem. 2019;294:10380.

  35. Expression of Concern: Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo: Role of mitochondrial reactive nitrogen species.
    J Biol Chem. 2019;294:10024.

  36. LI Y, Cooper A, Odibo IN, Ahmed A, et al
    Withdrawal: Discrepancy in insulin regulation between gestational diabetes mellitus (GDM) platelets and placenta.
    J Biol Chem. 2019;294:9656.

    May 2019
  37. LI Y, Deng S, Peng J, Wang X, et al
    MicroRNA-223 is essential for maintaining functional beta-cell mass during diabetes through inhibiting both FOXO1 and SOX6 pathways.
    J Biol Chem. 2019 May 22. pii: RA119.007755. doi: 10.1074/jbc.RA119.007755.
    PubMed     Abstract available

  38. CORSA CAS, Pearson GL, Renberg A, Askar MM, et al
    The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic beta cells and adipocytes.
    J Biol Chem. 2019;294:7296-7307.
    PubMed     Abstract available

    April 2019
    The mystery of metformin.
    J Biol Chem. 2019;294:6689-6691.

  40. DONG X, Yu S, Wang Y, Yang M, et al
    (Pro)renin receptor-mediated myocardial injury, apoptosis, and inflammatory response in rats with diabetic cardiomyopathy.
    J Biol Chem. 2019 Apr 5. pii: RA119.007648. doi: 10.1074/jbc.RA119.007648.
    PubMed     Abstract available

  41. DIERSCHKE SK, Miller WP, Favate JS, Shah P, et al
    O-GlcNAcylation alters the selection of mRNAs for translation and promotes 4E-BP1-dependent mitochondrial dysfunction in the retina.
    J Biol Chem. 2019;294:5508-5520.
    PubMed     Abstract available

    March 2019
  42. LI Y, Cooper A, Odibo IN, Ahmed A, et al
    Expression of Concern: Discrepancy in insulin regulation between gestational diabetes mellitus (GDM) platelets and placenta.
    J Biol Chem. 2019;294:5208.

  43. CLOSE AF, Dadheech N, Villela BS, Rouillard C, et al
    The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of beta-cell mass.
    J Biol Chem. 2019;294:4889-4897.
    PubMed     Abstract available

  44. VAN KRIEKEN R, Mehta N, Wang T, Zheng M, et al
    Cell surface expression of 78 kDa glucose regulated protein (GRP78) mediates diabetic nephropathy.
    J Biol Chem. 2019 Mar 26. pii: RA118.006939. doi: 10.1074/jbc.RA118.006939.
    PubMed     Abstract available

    February 2019
  45. HART GW
    Nutrient regulation of signaling and transcription.
    J Biol Chem. 2019;294:2211-2231.
    PubMed     Abstract available

    January 2019
  46. MICHAEL ES, Covic L, Kuliopulos A
    TAAR1 promotes anti-diabetic signaling in insulin-secreting cells.
    J Biol Chem. 2019 Jan 22. pii: RA118.005464. doi: 10.1074/jbc.RA118.005464.
    PubMed     Abstract available

  47. LING TY, Yi F, Lu T, Wang XL, et al
    F-box protein-32 down-regulates small-conductance calcium-activated potassium channel 2 in diabetic mouse atria.
    J Biol Chem. 2019 Jan 11. pii: RA118.003837. doi: 10.1074/jbc.RA118.003837.
    PubMed     Abstract available

  48. YAMAMOTO WR, Bone RN, Sohn P, Syed F, et al
    Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic beta cell.
    J Biol Chem. 2019;294:168-181.
    PubMed     Abstract available

    September 2018
  49. WARD MG, Li G, Hao M
    Apoptotic beta-cells induce macrophage reprogramming under diabetic conditions.
    J Biol Chem. 2018 Sep 13. pii: RA118.004565. doi: 10.1074/jbc.RA118.004565.
    PubMed     Abstract available

    June 2018
  50. KEFALAS G, Jouvet N, Baldwin C, Estall JL, et al
    Peptide-based sequestration of the adaptor protein Nck1 in pancreatic beta cells enhances insulin biogenesis and protects against diabetogenic stresses.
    J Biol Chem. 2018 Jun 25. pii: RA118.002728. doi: 10.1074/jbc.RA118.002728.
    PubMed     Abstract available

    April 2018
  51. SUAREZ J, Cividini F, Scott BT, Lehmann K, et al
    Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function.
    J Biol Chem. 2018 Apr 6. pii: RA118.002066. doi: 10.1074/jbc.RA118.002066.
    PubMed     Abstract available

    December 2017
  52. HAHN C, Tyka K, Saba JD, Lenzen S, et al
    Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity.
    J Biol Chem. 2017;292:20292-20304.
    PubMed     Abstract available

    October 2017
  53. KROUT D, Schaar A, Sun Y, Sukumaran P, et al
    The TRPC1 Ca2+-permeable channel inhibits exercise-induced protection against high-fat diet-induced obesity and type II diabetes.
    J Biol Chem. 2017 Oct 26. pii: jbc.M117.809954. doi: 10.1074/jbc.M117.809954.
    PubMed     Abstract available

  54. XIONG Y, Zhang Y, Xin N, Yuan Y, et al
    1alpha,25-Dihydroxyvitamin D3 promotes bone formation by promoting nuclear exclusion of the FoxO1 transcription factor in diabetic mice.
    J Biol Chem. 2017 Oct 17. pii: jbc.M117.796367. doi: 10.1074/jbc.M117.796367.
    PubMed     Abstract available

    September 2017
  55. GLINIAK CM, Brown JM, Noy N
    The retinol-binding protein receptor STRA6 regulates diurnal insulin responses.
    J Biol Chem. 2017;292:15080-15093.
    PubMed     Abstract available

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