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COVID-19: Daily Top 10 Papers


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1 Am J Cardiol
3 Ann Intern Med
5 Biochem Biophys Res Commun
1 BMC Pediatr
1 Circ Heart Fail
3 Diabet Med
1 Diabetes
9 Diabetes Care
2 Diabetes Obes Metab
6 Diabetologia
1 Hypertension
2 J Am Soc Nephrol
1 J Biol Chem
2 J Clin Endocrinol Metab
4 J Diabetes Complications
2 J Exp Med
1 J Immunol
3 Kidney Int
1 Lancet
2 Med J Aust
1 Metabolism
1 Nat Genet
1 Nature
1 Ophthalmology
2 Pediatr Diabetes
8 PLoS One
1 Transplantation

  Retrieve available abstracts of this week’s articles:
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Single Articles

    Am J Cardiol

  1. BISWAS S, Dinh D, Andrianopoulos N, Lefkovits J, et al
    Comparison of Long-Term Outcomes After Percutaneous Coronary Intervention in Patients With Insulin-Treated vs. Non-Insulin Treated Diabetes Mellitus.
    Am J Cardiol. 2021 Mar 2. pii: S0002-9149(21)00200.
    PubMed         Abstract available

    Ann Intern Med

  2. KARAGIANNIS T, Tsapas A, Bekiari E
    KDIGO made 12 recommendations for managing diabetes with CKD.
    Ann Intern Med. 2021 Mar 2. doi: 10.7326/ACPJ202103160.
    PubMed         Abstract available

  3. SMETANA GW, Tetrault JM, Hill KP, Burns RB, et al
    Should You Recommend Cannabinoids for This Patient With Painful Neuropathy? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med. 2021 Feb 9. doi: 10.7326/M20-7945.
    PubMed         Abstract available

  4. HICKS CW, Wang D, Matsushita K, Windham BG, et al
    Peripheral Neuropathy and All-Cause and Cardiovascular Mortality in U.S. Adults : A Prospective Cohort Study.
    Ann Intern Med. 2020 Dec 8. doi: 10.7326/M20-1340.
    PubMed         Abstract available

    Biochem Biophys Res Commun

  5. LI L, Dong S, Li S, Xu Q, et al
    Downregulation of circular RNA circDOCK7 identified from diabetic rats after sleeve gastrectomy contributes to hepatocyte apoptosis through regulating miR-139-3p and MCM3.
    Biochem Biophys Res Commun. 2021;548:134-142.
    PubMed         Abstract available

  6. ZHANG N, Liu C, Zhang Y, Xu D, et al
    Liraglutide regulates lipid metabolism via FGF21- LKB1- AMPK- ACC1 pathway in white adipose tissues and macrophage of type 2 diabetic mice.
    Biochem Biophys Res Commun. 2021;548:120-126.
    PubMed         Abstract available

  7. WANG X, Li T, Ma B, Zhao Z, et al
    Melatonin attenuates restenosis after vascular injury in diabetic rats through activation of the Nrf2 signaling pathway.
    Biochem Biophys Res Commun. 2021;548:127-133.
    PubMed         Abstract available

  8. YING F, Liu H, Ching Tang EH, Lakhani I, et al
    Prostaglandin E receptor subtype 4 protects against diabetic cardiomyopathy by modulating cardiac fatty acid metabolism via FOXO1/CD36 signalling.
    Biochem Biophys Res Commun. 2021;548:196-203.
    PubMed         Abstract available

  9. LI Y, Zhao J, Wu Y, Xia L, et al
    Btk knockout attenuates the liver inflammation in STZ-induced diabetic mice by suppressing NLRP3 inflammasome activation.
    Biochem Biophys Res Commun. 2021;549:75-82.
    PubMed         Abstract available

    BMC Pediatr

  10. KIM JH, Lee Y, Choi Y, Kim GH, et al
    Etiologic distribution and clinical characteristics of pediatric diabetes in 276 children and adolescents with diabetes at a single academic center.
    BMC Pediatr. 2021;21:108.
    PubMed         Abstract available

    Circ Heart Fail

  11. TAMAKI S, Yamada T, Watanabe T, Morita T, et al
    Effect of Empagliflozin as an Add-On Therapy on Decongestion and Renal Function in Patients With Diabetes Hospitalized for Acute Decompensated Heart Failure: A Prospective Randomized Controlled Study.
    Circ Heart Fail. 2021 Mar 5:CIRCHEARTFAILURE120007048.
    PubMed         Abstract available

    Diabet Med

  12. MCKEOWN J, McGeoch PD, Grieve DJ
    The influence of vestibular stimulation on metabolism and body composition.
    Diabet Med. 2020;37:20-28.
    PubMed         Abstract available

  13. ROWLANDS AV, Henson JJ, Coull NA, Edwardson CL, et al
    The impact of COVID-19 restrictions on accelerometer-assessed physical activity and sleep in individuals with type 2 diabetes.
    Diabet Med. 2021 Mar 1:e14549. doi: 10.1111/dme.14549.
    PubMed         Abstract available

  14. HADJICONSTANTINOU M, Barker MM, Brough C, Schreder S, et al
    Improved diabetes-related distress and self-efficacy outcomes in a self-management digital programme for people with type 2 diabetes, myDESMOND.
    Diabet Med. 2021 Mar 6:e14551. doi: 10.1111/dme.14551.
    PubMed         Abstract available


  15. NIU T, Fang J, Shi X, Zhao M, et al
    Pathogenesis study based on high throughput single-cell sequencing analysis reveals novel transcriptional landscape and heterogeneity of retinal cells in type 2 diabetic mice.
    Diabetes. 2021 Mar 5. pii: db20-0839. doi: 10.2337/db20-0839.
    PubMed         Abstract available

    Diabetes Care

  16. SIVITZ WI, Phillips LS, Wexler DJ, Fortmann SP, et al
    Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight.
    Diabetes Care. 2020;43:940-947.
    PubMed         Abstract available

  17. CHEN C, Chen Q, Nie B, Zhang H, et al
    Trends in Bone Mineral Density, Osteoporosis, and Osteopenia Among U.S. Adults With Prediabetes, 2005-2014.
    Diabetes Care. 2020;43:1008-1015.
    PubMed         Abstract available

  18. SCOTT EM, Feig DS, Murphy HR, Law GR, et al
    Continuous Glucose Monitoring in Pregnancy: Importance of Analyzing Temporal Profiles to Understand Clinical Outcomes.
    Diabetes Care. 2020;43:1178-1184.
    PubMed         Abstract available

  19. SHENG CS, Tian J, Miao Y, Cheng Y, et al
    Prognostic Significance of Long-term HbA1c Variability for All-Cause Mortality in the ACCORD Trial.
    Diabetes Care. 2020;43:1185-1190.
    PubMed         Abstract available

  20. LE P, Chaitoff A, Misra-Hebert AD, Ye W, et al
    Use of Antihyperglycemic Medications in U.S. Adults: An Analysis of the National Health and Nutrition Examination Survey.
    Diabetes Care. 2020;43:1227-1233.
    PubMed         Abstract available

  21. LAICHUTHAI N, Abdul-Ghani M, Kosiborod M, Parksook WW, et al
    Newly Discovered Abnormal Glucose Tolerance in Patients With Acute Myocardial Infarction and Cardiovascular Outcomes: A Meta-analysis.
    Diabetes Care. 2020;43:1958-1966.
    PubMed         Abstract available

  22. CARDONA-HERNANDEZ R, Schwandt A, Alkandari H, Bratke H, et al
    Glycemic Outcome Associated With Insulin Pump and Glucose Sensor Use in Children and Adolescents With Type 1 Diabetes. Data From the International Pediatric Registry SWEET.
    Diabetes Care. 2021 Mar 2. pii: dc20-1674. doi: 10.2337/dc20-1674.
    PubMed         Abstract available

  23. KRISTOFI R, Bodegard J, Norhammar A, Thuresson M, et al
    Cardiovascular and Renal Disease Burden in Type 1 Compared With Type 2 Diabetes: A Two-Country Nationwide Observational Study.
    Diabetes Care. 2021 Mar 2. pii: dc20-2839. doi: 10.2337/dc20-2839.
    PubMed         Abstract available

  24. QIAN F, Ardisson Korat AV, Imamura F, Marklund M, et al
    n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies.
    Diabetes Care. 2021 Mar 3. pii: dc20-2426. doi: 10.2337/dc20-2426.
    PubMed         Abstract available

    Diabetes Obes Metab

  25. LING JZJ, Montvida O, Khunti K, Zhang AL, et al
    Therapeutic inertia in the management of dyslipidaemia and hypertension in incident type 2 diabetes and the resulting risk factor burden: real-world evidence from primary care.
    Diabetes Obes Metab. 2021 Mar 2. doi: 10.1111/dom.14364.
    PubMed         Abstract available

  26. GOMEZ-PERALTA F, Al-Ozairi E, Jude EB, Li X, et al
    Titratable Fixed-Ratio Combination of Basal Insulin Plus a GLP-1 Receptor Agonist: A Novel, Simplified Alternative to Premix Insulin for Type 2 Diabetes.
    Diabetes Obes Metab. 2021 Mar 2. doi: 10.1111/dom.14365.
    PubMed         Abstract available


  27. PERKINS BA, Lovblom LE, Lanctot SO, Lamb K, et al
    Discoveries from the study of longstanding type 1 diabetes.
    Diabetologia. 2021 Mar 4. pii: 10.1007/s00125-021-05403.
    PubMed         Abstract available

  28. TONNIES T, Hoyer A, Brinks R
    Productivity-adjusted life years lost due to type 2 diabetes in Germany in 2020 and 2040.
    Diabetologia. 2021 Mar 4. pii: 10.1007/s00125-021-05409.
    PubMed         Abstract available

  29. PURVIS N, Kumari S, Chandrasekera D, Bellae Papannarao J, et al
    Diabetes induces dysregulation of microRNAs associated with survival, proliferation and self-renewal in cardiac progenitor cells.
    Diabetologia. 2021 Mar 2. pii: 10.1007/s00125-021-05405.
    PubMed         Abstract available

  30. MORRISON KR, Solly EL, Shemesh T, Psaltis PJ, et al
    Elevated HDL-bound miR-181c-5p level is associated with diabetic vascular complications in Australian Aboriginal people.
    Diabetologia. 2021 Mar 2. pii: 10.1007/s00125-021-05414.
    PubMed         Abstract available

  31. CHERNEY DZI, Charbonnel B, Cosentino F, Dagogo-Jack S, et al
    Effects of ertugliflozin on kidney composite outcomes, renal function and albuminuria in patients with type 2 diabetes mellitus: an analysis from the randomised VERTIS CV trial.
    Diabetologia. 2021 Mar 4. pii: 10.1007/s00125-021-05407.
    PubMed         Abstract available

  32. GUO C, Yang HT, Chang LY, Bo Y, et al
    Habitual exercise is associated with reduced risk of diabetes regardless of air pollution: a longitudinal cohort study.
    Diabetologia. 2021 Mar 4. pii: 10.1007/s00125-021-05408.
    PubMed         Abstract available


  33. ISHIZAWA R, Kim HK, Hotta N, Iwamoto GA, et al
    TRPV1 (Transient Receptor Potential Vanilloid 1) Sensitization of Skeletal Muscle Afferents in Type 2 Diabetic Rats With Hyperglycemia.
    Hypertension. 2021 Mar 1:HYPERTENSIONAHA12015672.
    PubMed         Abstract available

    J Am Soc Nephrol

  34. SHIN JI, Sang Y, Chang AR, Dunning SC, et al
    The FDA Metformin Label Change and Racial and Sex Disparities in Metformin Prescription among Patients with CKD.
    J Am Soc Nephrol. 2020;31:1847-1858.
    PubMed         Abstract available

  35. OSHIMA M, Neal B, Toyama T, Ohkuma T, et al
    Different eGFR Decline Thresholds and Renal Effects of Canagliflozin: Data from the CANVAS Program.
    J Am Soc Nephrol. 2020;31:2446-2456.
    PubMed         Abstract available

    J Biol Chem

  36. LOPEZ-SOLDADO I, Guinovart JJ, Duran J
    Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice.
    J Biol Chem. 2021 Mar 2:100498. doi: 10.1016/j.jbc.2021.100498.
    PubMed         Abstract available

    J Clin Endocrinol Metab

  37. GALINDO RJ, Pasquel FJ, Vellanki P, Zambrano C, et al
    Biochemical Parameters of Diabetes Ketoacidosis in patients with End-Stage Kidney Disease and Preserved Renal Function.
    J Clin Endocrinol Metab. 2021 Feb 28. pii: 6154458. doi: 10.1210.
    PubMed         Abstract available

  38. HORBER S, Lehmann R, Fritsche L, Machann J, et al
    Lifestyle intervention improves prothrombotic coagulation profile in individuals at high-risk for type 2 diabetes.
    J Clin Endocrinol Metab. 2021 Feb 28. pii: 6154459. doi: 10.1210.
    PubMed         Abstract available

    J Diabetes Complications

  39. CUI Y, Liu J, Shi H, Hu W, et al
    Serum uric acid is positively associated with the prevalence of nonalcoholic fatty liver in non-obese type 2 diabetes patients in a Chinese population.
    J Diabetes Complications. 2021 Feb 16:107874.
    PubMed         Abstract available

  40. MIN D, Nube V, Tao A, Yuan X, et al
    Monocyte phenotype as a predictive marker for wound healing in diabetes-related foot ulcers.
    J Diabetes Complications. 2021 Feb 16:107889.
    PubMed         Abstract available

  41. RATLIFF HT, Shibuya N, Jupiter DC
    Minor vs. major leg amputation in adults with diabetes: Six-month readmissions, reamputations, and complications.
    J Diabetes Complications. 2021 Feb 15:107886.
    PubMed         Abstract available

  42. ZHANG D, Yang Y, Li R, Li Z, et al
    Comparison of long-term outcomes between Chinese peritoneal dialysis patients with and without diabetes: A 10-year cohort study.
    J Diabetes Complications. 2021 Feb 15:107888.
    PubMed         Abstract available

    J Exp Med

  43. MENG KP, Majedi FS, Thauland TJ, Butte MJ, et al
    Mechanosensing through YAP controls T cell activation and metabolism.
    J Exp Med. 2020;217.
    PubMed         Abstract available

  44. ANGELETTI A, Cantarelli C, Petrosyan A, Andrighetto S, et al
    Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis.
    J Exp Med. 2020;217.
    PubMed         Abstract available

    J Immunol

  45. NANDEDKAR-KULKARNI N, Esakov E, Gregg B, Atkinson MA, et al
    Insulin Receptor-Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice.
    J Immunol. 2021 Mar 3. pii: jimmunol.1900357. doi: 10.4049/jimmunol.1900357.
    PubMed         Abstract available

    Kidney Int

  46. VAN RAALTE DH, Bjornstad P, Heerspink HJL, Persson F, et al
    Importance of standardizing renal outcomes in clinical trials: illustration by recent sodium glucose cotransporter 2 inhibitor studies.
    Kidney Int. 2021;99:768-770.

  47. GREGG LP, Navaneethan SD
    Early eGFR decline after SGLT2i initiation: knowns and unknowns.
    Kidney Int. 2021;99:548-550.
    PubMed         Abstract available

  48. WU L, Liu C, Chang DY, Zhan R, et al
    Annexin A1 alleviates kidney injury by promoting the resolution of inflammation in diabetic nephropathy.
    Kidney Int. 2021 Mar 3. pii: S0085-2538(21)00267.
    PubMed         Abstract available


  49. DAVIES M, Faerch L, Jeppesen OK, Pakseresht A, et al
    Semaglutide 2.4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial.
    Lancet. 2021 Mar 2. pii: S0140-6736(21)00213.
    PubMed         Abstract available

    Med J Aust

  50. SNAITH JR, Holmes-Walker DJ
    Technologies in the management of type 1 diabetes.
    Med J Aust. 2021 Feb 28. doi: 10.5694/mja2.50946.

  51. HAYNES A, Curran JA, Davis EA
    Two decades of increasing incidence of childhood-onset type 2 diabetes in Western Australia (2000-2019).
    Med J Aust. 2021 Feb 27. doi: 10.5694/mja2.50970.


  52. WU M, Yang Z, Zhang C, Shi Y, et al
    Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy.
    Metabolism. 2021 Mar 3:154748. doi: 10.1016/j.metabol.2021.154748.
    PubMed         Abstract available

    Nat Genet

  53. SINNOTT-ARMSTRONG N, Tanigawa Y, Amar D, Mars N, et al
    Genetics of 35 blood and urine biomarkers in the UK Biobank.
    Nat Genet. 2021;53:185-194.
    PubMed         Abstract available


  54. An antibody joins forces with the pancreas to delay diabetes.
    Nature. 2021 Mar 4. pii: 10.1038/d41586-021-00588.


  55. CUI Y, Zhu Y, Lu ES, Le R, et al
    Widefield Swept-source OCT Angiography Metrics Associated with the Development of Diabetic Vitreous Hemorrhage A Prospective Study.
    Ophthalmology. 2021 Feb 26. pii: S0161-6420(21)00154.
    PubMed         Abstract available

    Pediatr Diabetes

  56. MAZOR-ARONOVITCH K, Pinhas-Hamiel O, Pivko-Levy D, Modan-Moses D, et al
    Dual diagnosis of type 1 diabetes mellitus and attention deficit hyperactivity disorder.
    Pediatr Diabetes. 2021 Mar 2. doi: 10.1111/pedi.13195.
    PubMed         Abstract available

  57. SARNBLAD S, Ponsot E, Lepretre PM, Kadi F, et al
    Acute effects of aerobic continuous, intermittent and resistance exercise on glycemia in adolescents males with type 1 diabetes.
    Pediatr Diabetes. 2021 Mar 1. doi: 10.1111/pedi.13194.
    PubMed         Abstract available

    PLoS One

  58. RUIZ-QUINONEZ JA, Guzman-Priego CG, Nolasco-Rosales GA, Tovilla-Zarate CA, et al
    Features of patients that died for COVID-19 in a hospital in the south of Mexico: A observational cohort study.
    PLoS One. 2021;16:e0245394.
    PubMed         Abstract available

  59. WINTHER SA, Ollgaard JC, Hansen TW, von Scholten BJ, et al
    Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria.
    PLoS One. 2021;16:e0244402.
    PubMed         Abstract available

  60. CHO WR, Wang CC, Tsai MY, Chou CK, et al
    Impact of metformin use on the recurrence of hepatocellular carcinoma after initial liver resection in diabetic patients.
    PLoS One. 2021;16:e0247231.
    PubMed         Abstract available

  61. REFAT MS, Hamza RZ, Adam AMA, Saad HA, et al
    Quercetin/Zinc complex and stem cells: A new drug therapy to ameliorate glycometabolic control and pulmonary dysfunction in diabetes mellitus: Structural characterization and genetic studies.
    PLoS One. 2021;16:e0246265.
    PubMed         Abstract available

  62. D'AMICO M, Kinel E, Roncoletta P, Gnaldi A, et al
    Data-driven CAD-CAM vs traditional total contact custom insoles: A novel quantitative-statistical framework for the evaluation of insoles offloading performance in diabetic foot.
    PLoS One. 2021;16:e0247915.
    PubMed         Abstract available

  63. BOSHE BD, Yimar GN, Dadhi AE, Bededa WK, et al
    The magnitude of non-adherence and contributing factors among adult outpatient with Diabetes Mellitus in Dilla University Referral Hospital, Gedio, Ethiopia.
    PLoS One. 2021;16:e0247952.
    PubMed         Abstract available

  64. Correction: Correction: Inactive matrix gla protein plasma levels are associated with peripheral neuropathy in Type 2 diabetes.
    PLoS One. 2021;16:e0248441.
    PubMed         Abstract available

  65. LEI J, Ding G, Xie A, Hu Y, et al
    Aqueous humor monocyte chemoattractant protein-1 predicted long-term visual outcome of proliferative diabetic retinopathy undergone intravitreal injection of bevacizumab and vitrectomy.
    PLoS One. 2021;16:e0248235.
    PubMed         Abstract available


  66. MONTAGUD-MARRAHI E, Molina-Andujar A, Pane A, Ruiz S, et al
    Impact of Simultaneous Pancreas-kidney Transplantation on Cardiovascular Risk in Patients With Diabetes.
    Transplantation. 2021 Mar 2. pii: 00007890-900000000-95328.
    PubMed         Abstract available

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