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  Diabetes

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27.04.2026

1 Am J Ophthalmol
2 Ann Intern Med
1 Atherosclerosis
2 Biochem Biophys Res Commun
2 BMC Ophthalmol
1 Br J Ophthalmol
6 Diabet Med
3 Diabetes
10 Diabetes Care
16 Diabetes Obes Metab
8 Diabetologia
1 Invest Ophthalmol Vis Sci
1 J Am Coll Cardiol
5 J Clin Endocrinol Metab
1 J Diabetes Complications
1 J Immunol
1 Med Care
1 Ophthalmology
3 Pediatrics
1 PLoS Med
3 PLoS One


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Ophthalmol

  1. SHAH J, Makwana B, Panchal K, Patel V, et al
    Glucagon-Like Peptide-1 Receptor Agonists and Risk of Systemic and Ocular Vascular Complications in Patients with Type 2 Diabetes and Diabetic Retinopathy.
    Am J Ophthalmol. 2026 Apr 21:S0002-9394(26)00219.
    PubMed         Abstract available


    Ann Intern Med


  2. Correction: Association of State Insulin Out-of-Pocket Caps With Insulin Cost-Sharing and Use Among Commercially Insured Patients With Diabetes.
    Ann Intern Med. 2026 Apr 21. doi: 10.7326/ANNALS-26-01314.
    PubMed        

  3. MCDONNELL DJ, Dinneen SF
    In adults with T1D and overweight or obesity, adding GLP-1 RAs to insulin reduces weight, HbA(1c) levels, and insulin dose.
    Ann Intern Med. 2026;179:JC44.
    PubMed         Abstract available


    Atherosclerosis

  4. SCHONCK WA, Hovingh GK, Blom DJ, Tromp T, et al
    Traditional cardiovascular risk factors and their association with atherosclerotic cardiovascular disease in homozygous familial hypercholesterolemia: A cross-sectional analysis from the HICC registry.
    Atherosclerosis. 2026;415:120717.
    PubMed         Abstract available


    Biochem Biophys Res Commun

  5. ANTO EM, M A, Jayamurthy P
    ER stress: A putative therapeutic target for diabetes mellitus.
    Biochem Biophys Res Commun. 2026;818:153773.
    PubMed         Abstract available

  6. ZHANG B, Li P, Jiang N, Xue W, et al
    Hydrogen sulfide improves keratinocytes migration and diabetic skin wound healing via plakophilin 4.
    Biochem Biophys Res Commun. 2026;818:153779.
    PubMed         Abstract available


    BMC Ophthalmol

  7. ZHOU B, Liu H, Xiong F
    hsa_circ_0068631 facilitates the progression of diabetic retinopathy via regulating miR-140-5p in retinal microvascular endothelial cells.
    BMC Ophthalmol. 2026 Apr 20. doi: 10.1186/s12886-026-04819.
    PubMed        

  8. ZHANG M, Zhang X, Xia W, Zhao W, et al
    Effects of a nurse-led self-management intervention on health outcomes in patients with diabetic retinopathy undergoing vitrectomy: a randomized controlled trial.
    BMC Ophthalmol. 2026 Apr 18. doi: 10.1186/s12886-026-04826.
    PubMed         Abstract available


    Br J Ophthalmol

  9. CHALKIADAKI E, Sim YS, Williams O, Elder L, et al
    Real-world early outcomes of intravitreal faricimab 6-mg and aflibercept 2-mg injection in diabetic macular oedema.
    Br J Ophthalmol. 2026 Apr 21:bjo-2025-328893. doi: 10.1136/bjo-2025-328893.
    PubMed         Abstract available


    Diabet Med

  10. SUGLO JN, Winkley K, Abeasi DA, Sturt J, et al
    Reverse innovation in diabetic foot disease prevention: Rethinking family and community roles.
    Diabet Med. 2026 Apr 18:e70336. doi: 10.1111/dme.70336.
    PubMed        

  11. LEKSELL JK, Granstam E, Granstrom T, Nerpin E, et al
    Health, hope and worry: A qualitative study of people with diabetes' experiences with anti-VEGF treatment.
    Diabet Med. 2026 Apr 20:e70334. doi: 10.1111/dme.70334.
    PubMed         Abstract available

  12. AHIMSADASAN N, Wu W, Rahman I, Sherifali D, et al
    The risk of postpartum depressive symptoms in immigrant women with recent gestational diabetes mellitus.
    Diabet Med. 2026 Apr 20:e70339. doi: 10.1111/dme.70339.
    PubMed         Abstract available


  13. Supplement: Abstracts of the Diabetes UK Professional Conference 2026, Exhibition Centre Liverpool, 22-24 April 2026.
    Diabet Med. 2026;43 Suppl 1:e70287.
    PubMed        

  14. WYATT RC, Brigatti C, Grace SL, Williams CL, et al
    Improved prediction of symptomatic type 1 diabetes using a luciferase-based assay to measure (pro)insulin autoantibodies.
    Diabet Med. 2026 Apr 23:e70277. doi: 10.1111/dme.70277.
    PubMed         Abstract available

  15. NIELSEN S, Thomsen MB, Nyvad J, Laugesen E, et al
    Obstructive sleep apnoea is associated with accelerated progression of diabetic kidney disease.
    Diabet Med. 2026 Apr 23:e70340. doi: 10.1111/dme.70340.
    PubMed         Abstract available


    Diabetes

  16. ZHAO C, Hatzikotoulas K, Balasubramanian R, Bertone-Johnson E, et al
    Associations of Combined Genetic and Lifestyle Risks With Incident Type 2 Diabetes in the UK Biobank.
    Diabetes. 2026;75:860-866.
    PubMed         Abstract available

  17. PAGE B
    Diabetes Spotlight: Jennifer Estall, PhD-Identifying Signals Between the Pancreas and Liver.
    Diabetes. 2026;75:751.
    PubMed        

  18. BUZIAU AM, Wesselius A, Yu EY, Korver-Keularts IMLW, et al
    Metabolite Erythritol in 24-Hour Urine Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study.
    Diabetes. 2026;75:762-771.
    PubMed         Abstract available


    Diabetes Care

  19. GANESHALINGAM AA, Uhrenholt N, Arnfred S, Gaede P, et al
    Semaglutide Effects on Insulin Sensitivity and beta-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial W
    Diabetes Care. 2026 Mar 4:dc252041. doi: 10.2337/dc25-2041.
    PubMed         Abstract available

  20. WARMBRUNN MV, Yang L, Kishore Biswas R, Ryan CP, et al
    Weight Regain Reverses Caloric Restriction-Induced Benefits on the Insulin-IGF-1 Nutrient-Sensing Pathway: Post Hoc Analysis From the CALERIE-2 Randomized Controlled Trial.
    Diabetes Care. 2026;49:783-791.
    PubMed         Abstract available

  21. ABDUL-GHANI M, Abu-Farha M, Abdul-Ghani T, Chavez-Velazquez A, et al
    Response to Comment on Abdul-Ghani et al. One-Hour Plasma Glucose Predicts the Progression From Normal Glucose Tolerance to Prediabetes. Diabetes Care 2025;48:1273-1279.
    Diabetes Care. 2026;49:e83.
    PubMed        

  22. ALEXOPOULOS AS, Cusi K
    Integrating Alcohol Use Into MASLD Care: A Practical Guide for Diabetes and Obesity Care Teams.
    Diabetes Care. 2026 Apr 20:dci260019. doi: 10.2337/dci26-0019.
    PubMed         Abstract available

  23. JIN Y, Jin Y, Zhang G
    Comment on Valent et al. Real-Time Continuous Glucose Monitoring in Pregnancies With Gestational Diabetes Mellitus: A Randomized Controlled Trial. Diabetes Care 2025;48:1581-1588.
    Diabetes Care. 2026;49:e84-e85.
    PubMed        

  24. KIGUCHI M, Fujikawa T
    Comment on Abdul-Ghani et al. One-Hour Plasma Glucose Predicts the Progression From Normal Glucose Tolerance to Prediabetes. Diabetes Care 2025;48:1273-1279.
    Diabetes Care. 2026;49:e82.
    PubMed        

  25. VALENT AM, Ward L
    Response to Comment on Valent et al. Real-Time Continuous Glucose Monitoring in Pregnancies With Gestational Diabetes Mellitus: A Randomized Controlled Trial. Diabetes Care 2025;48:1581-1588.
    Diabetes Care. 2026;49:e86-e87.
    PubMed        

  26. DOVE C, Pop-Busui R
    From Glucose to Limb Salvage: New Therapeutic Frontiers to Redefine Outcomes in Diabetic Foot Disease.
    Diabetes Care. 2026;49:709-710.
    PubMed        

  27. LEMOS JRN, Skyler JS
    Oral Insulin for Type 1 Diabetes Prevention.
    Diabetes Care. 2026;49:715-717.
    PubMed        

  28. PAGE B
    About the Editor: John B. Buse, MD, PhD-Clinical Research for the Prevention and Treatment of Diabetes.
    Diabetes Care. 2026;49:694.
    PubMed        


    Diabetes Obes Metab

  29. MA C, Dai Z, Xiao B, Chen Y, et al
    Integrative Proteomic and Machine Learning Analysis Identifies Novel Predictors and Risk Model for Diabetic Macrovascular Complications.
    Diabetes Obes Metab. 2026 Apr 22. doi: 10.1111/dom.70807.
    PubMed         Abstract available

  30. KOBAYASHI G, Hashimoto Y, Matsuyama T, Kitagawa N, et al
    Bifidobacteriuradm bifidum G9-1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open-Label, Randomized Controlled Trial (Binary STAR Study).
    Diabetes Obes Metab. 2026 Apr 22. doi: 10.1111/dom.70805.
    PubMed         Abstract available

  31. CHERDRON C, Achenbach P, Ackermann K, Haupt F, et al
    Health Care Provider Perceptions of Screening for Early-Stage Type 1 Diabetes-A Survey Study.
    Diabetes Obes Metab. 2026 Apr 22. doi: 10.1111/dom.70803.
    PubMed         Abstract available

  32. YAN H, Zhuang M, Liu Q, Wan X, et al
    Comparative Effects of Different Exercise Modalities on Circulating Adipokines and Inflammatory Cytokines in Adults With Type 2 Diabetes: A Network Meta-Analysis.
    Diabetes Obes Metab. 2026 Apr 24. doi: 10.1111/dom.70780.
    PubMed         Abstract available

  33. SCHMIDT S, Kristensen KB, McCarthy OM, Bracken RM, et al
    Low-Dose Glucagon After Fasted Morning Exercise in People With Type 1 Diabetes-A Randomised Crossover Comparison of Low and High Carbohydrate Diets.
    Diabetes Obes Metab. 2026 Apr 24. doi: 10.1111/dom.70777.
    PubMed        

  34. LIARAKOS AL, Randhay A, Leelarathna L, Crabtree TSJ, et al
    Continuous Glucose Monitoring in Adults With Diabetes Receiving Haemodialysis: Identifying Dialysis-Specific Glycaemic Patterns and Associations With Volume Status and Intradialytic Hypoglycaemia.
    Diabetes Obes Metab. 2026 Apr 24. doi: 10.1111/dom.70808.
    PubMed         Abstract available

  35. NEVES JS, Leite AR, Vasques-Novoa F, Pitt B, et al
    Outcomes With Finerenone by Baseline Treatment Goals in Type 2 Diabetes and Chronic Kidney Disease: A FIDELITY Analysis.
    Diabetes Obes Metab. 2026 Apr 24. doi: 10.1111/dom.70750.
    PubMed         Abstract available

  36. LUO Y, Jin Z, Zhao Y, Luo Y, et al
    Gastric Emptying Is a Major Determinant of Postprandial Glycaemia and Prandial Insulin Requirement in Chinese With Type 1 Diabetes.
    Diabetes Obes Metab. 2026 Apr 24. doi: 10.1111/dom.70811.
    PubMed        

  37. LIN TM, Chang HF, Lin TC, Lin CH, et al
    Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR-Based beta-Cell Replacement and Treg Immune Modulation Approaches.
    Diabetes Obes Metab. 2026 Apr 23. doi: 10.1111/dom.70800.
    PubMed         Abstract available

  38. OVERGAARD RV, Birkhan O, Rathor N, Sparso T, et al
    Efficacy, Safety and PK of Once-Daily Oral Semaglutide 25 mg for Obesity With and Without Type 2 Diabetes in Comparison With Subcutaneous Semaglutide 2.4 mg: A Model-Informed Drug Development Approach.
    Diabetes Obes Metab. 2026 Apr 23. doi: 10.1111/dom.70769.
    PubMed         Abstract available

  39. VILLA-FERNANDEZ E, Garcia AV, Gallardo-Nuell L, Garcia-Villarino M, et al
    Integrated miRNA-mRNA Analysis Reveals Obesity-Driven Regulatory Networks in Human Visceral Adipose Tissue With and Without Type 2 Diabetes.
    Diabetes Obes Metab. 2026 Apr 23. doi: 10.1111/dom.70787.
    PubMed         Abstract available

  40. WU T, Rayner CK, Jones KL, Marathe CS, et al
    Gastroparesis in Type 1 Diabetes: Myths, Facts and Relevance to Automated Insulin Delivery.
    Diabetes Obes Metab. 2026 Apr 20. doi: 10.1111/dom.70793.
    PubMed        

  41. HUANG YN, Tsou MY, Li PH, Chen JC, et al
    Associations of Semaglutide With Skeletal Outcomes in People With Obesity, With and Without Type 2 Diabetes: A Target Trial Emulation.
    Diabetes Obes Metab. 2026 Apr 20. doi: 10.1111/dom.70786.
    PubMed         Abstract available

  42. YOU Q, Gao Y, Fang Z, Zeng J, et al
    Discretionary Screen Time and Progression From Prediabetes to Type 2 Diabetes: Mediating Roles of Sleep and the Triglyceride-Glucose Index.
    Diabetes Obes Metab. 2026 Apr 20. doi: 10.1111/dom.70796.
    PubMed         Abstract available

  43. BELLASTELLA G, di Nuzzo M, Longo M, Cirillo P, et al
    Islet Autoantibodies in Adult With Pituitary and Ovarian Autoimmunity: Implications for Type 1 Diabetes Screening.
    Diabetes Obes Metab. 2026 Apr 20. doi: 10.1111/dom.70776.
    PubMed         Abstract available

  44. CHEN L, Horn P, Tacke F
    Providing holistic care for patients with metabolic dysfunction-associated steatotic liver disease/metabolic dysfunction-associated steatohepatitis: Key aspects of clinical assessment and how to develop individualised care plans for surveillance and i
    Diabetes Obes Metab. 2026;28 Suppl 2.
    PubMed         Abstract available


    Diabetologia

  45. MUSTAFAJEV IF, Hendriksz MS, Stienstra R, Tack CJ, et al
    Adrenaline is a prominent driver of inflammatory responses following hypoglycaemia.
    Diabetologia. 2026;69:1675-1685.
    PubMed         Abstract available

  46. ABDELMOEZ AM, Jollet M, Yu X, Rizo-Roca D, et al
    Thromboxane signalling links immune activation to enhanced glucose uptake in skeletal muscle.
    Diabetologia. 2026;69:1643-1658.
    PubMed         Abstract available

  47. LAVER TW, Sriram A, Wakeling MN, Siklar Z, et al
    Systematic analysis of loss-of-function variants across MODY genes demonstrates gene-specific effects and expands the spectrum of INS variants causing MODY.
    Diabetologia. 2026;69:1569-1580.
    PubMed         Abstract available

  48. SYED F, Krishnan P, Chang G, Rana J, et al
    Beta cell microRNAs function as molecular hubs of type 1 diabetes pathogenesis and as biomarkers of diabetes risk.
    Diabetologia. 2026 Apr 21. doi: 10.1007/s00125-026-06720.
    PubMed         Abstract available

  49. MEHTA K, Morton JI, Chen L, Anstey KJ, et al
    Age- and sex-specific trends in dementia mortality among people with and without diabetes: a multi-country population-based analysis.
    Diabetologia. 2026 Apr 21. doi: 10.1007/s00125-026-06725.
    PubMed         Abstract available

  50. SHAMSUTDINOVA D, Stahl D, Das-Munshi J
    Inequalities in type 2 diabetes incidence in a multiethnic population: a cohort study investigating the impact of ethnicity, migration and mental health comorbidities.
    Diabetologia. 2026 Apr 22. doi: 10.1007/s00125-026-06740.
    PubMed         Abstract available

  51. BABIR FJ, Marcotte-Chenard A, Sandilands RE, D'Amico A, et al
    Exercise snacks performed in real-world settings reduce postprandial hyperglycaemia and glycaemic variability in individuals living with type 2 diabetes: a randomised crossover study.
    Diabetologia. 2026 Apr 24. doi: 10.1007/s00125-026-06741.
    PubMed         Abstract available

  52. MAHAJAN N, Luo Q, Lukkes J, Abhyankar SD, et al
    Bmal1 overexpression in suprachiasmatic nucleus protects from retinal neurovascular deficits in a mouse model of diabetes.
    Diabetologia. 2026 Apr 24. doi: 10.1007/s00125-026-06734.
    PubMed         Abstract available


    Invest Ophthalmol Vis Sci

  53. PARK JC, Cross A, McAnany JJ
    Rod Pathway Dysfunction in Early-Stage Diabetic Retinopathy Assessed by ERG and Pupillometry.
    Invest Ophthalmol Vis Sci. 2026;67:53.
    PubMed         Abstract available


    J Am Coll Cardiol

  54. FIORETTI F, Petrie MC, Dickert NW, Butler J, et al
    Balancing Clinical and Ethical Considerations Related to Placebo Use in Trials of Incretin-Based Therapies in Heart Failure.
    J Am Coll Cardiol. 2026;87:2034-2043.
    PubMed         Abstract available


    J Clin Endocrinol Metab

  55. LIANG X, Han H, Shen X, Williams PL, et al
    Hair mercury levels, serum n-3 fatty acids, and pregnancy glucose outcomes among women from a fertility center.
    J Clin Endocrinol Metab. 2025 Oct 29:dgaf594. doi: 10.1210.
    PubMed         Abstract available

  56. CARRY PM, Kim S, Zwick NL, Buckner T, et al
    Increased Levels of the Vitamin D Metabolite Ratio are Protective Against Progression from Islet Autoimmunity to T1D.
    J Clin Endocrinol Metab. 2025 Oct 30:dgaf578. doi: 10.1210.
    PubMed         Abstract available

  57. SHARP LN, Colclough K, Murray Leech J, Cannon SJ, et al
    Population Prevalence, Penetrance, and Mortality for Genetically Confirmed MODY.
    J Clin Endocrinol Metab. 2026;111:e1388-e1395.
    PubMed         Abstract available

  58. MISKELLY MG, Lindqvist A, Jujic A, Hamilton A, et al
    HMGCR and Rosuvastatin Regulates GLP-1 Secretion and Expression-A Translational Study.
    J Clin Endocrinol Metab. 2026;111:e1343-e1355.
    PubMed         Abstract available

  59. HONDA M, Honda R, Nomura TK, Nishikado Y, et al
    Digenic HNF1A and ABCC8 Variants Provide Mechanistic Insight into Early-Onset Diabetes.
    J Clin Endocrinol Metab. 2026 Apr 23:dgag183. doi: 10.1210.
    PubMed         Abstract available


    J Diabetes Complications

  60. FRANCIS H, Januszewski AS, O'Rourke MB, Huang MLH, et al
    Unveiling novel biomarkers for diabetes-related complications through large-scale proteomics analysis: A FIELD sub-study.
    J Diabetes Complications. 2026;40:109330.
    PubMed         Abstract available


    J Immunol

  61. AL-HALLAF R, Agha Z, Caturegli P, Rosenberg A, et al
    Leveraging a naturally occurring IgM autoantibody to target diabetogenic T cells: a precision medicine approach to type 1 diabetes.
    J Immunol. 2026;215:vkag056.
    PubMed         Abstract available


    Med Care

  62. ALVA ML, Booppasiri S, Crowell A, Magee MF, et al
    Diabetes Diagnosis Patterns in Medicaid: How State Policy, Managed Care, and Social Vulnerability Shape Detection in Medicaid.
    Med Care. 2026 Apr 23. doi: 10.1097/MLR.0000000000002328.
    PubMed         Abstract available


    Ophthalmology

  63. SUN D, Tseng VL, Yu F, Coleman AL, et al
    Cardiovascular Risk and Eye Health: A Prospective Cohort Study of the Pooled Cohort Equations and Ocular Disease Incidence.
    Ophthalmology. 2025 Dec 29:S0161-6420(25)00802.
    PubMed         Abstract available


    Pediatrics

  64. KVIGNE VL, Birger C, Eagle J
    Prevalence of Obesity and Diabetes for American Indian Children on the Northern Great Plains.
    Pediatrics. 2026 Apr 21:e2025072559. doi: 10.1542/peds.2025-072559.
    PubMed         Abstract available

  65. KUTZ C, Alarcon-Andrade G, Aguilera E, Garfias C, et al
    Incidence and Severity of Type 1 Diabetes in Children Through the COVID-19 Pandemic in Chile.
    Pediatrics. 2026 Apr 23:e2025072191. doi: 10.1542/peds.2025-072191.
    PubMed         Abstract available

  66. KAMRATH C, Eckert AJ, Rosenbauer J, Holl RW, et al
    Type 1 Diabetes Incidence in Youth in the Context of the COVID-19 Pandemic.
    Pediatrics. 2026 Apr 23:e2025074996. doi: 10.1542/peds.2025-074996.
    PubMed        


    PLoS Med

  67. ROUT M, Aston CE, Duggirala R, Goring HH, et al
    Identification of lipid quantitative trait loci linked with cardiometabolic disease in Asian Indians and Europeans: A genome-wide association study and mendelian randomization.
    PLoS Med. 2026;23:e1005039.
    PubMed         Abstract available


    PLoS One

  68. MU L, Wang Z, Cao Y, Wang X, et al
    Comprehensive analysis of immune-related genes reveals diagnostic biomarkers and molecular subtypes in diabetic retinopathy.
    PLoS One. 2026;21:e0346725.
    PubMed         Abstract available

  69. HAIDL H, Tokic S, Weiss EC, Gallistl S, et al
    Acetylsalicylic acid modulates progression of endogenous thrombin potential in high-risk pregnancies.
    PLoS One. 2026;21:e0347788.
    PubMed         Abstract available

  70. TEH XR, Ang SH, Lee PJ, Mohd Ropidi MI, et al
    Primary health care interventions targeting diabetes, hypertension or dyslipidemia in Malaysia: A scoping review.
    PLoS One. 2026;21:e0346934.
    PubMed         Abstract available


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