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Articles published in PLoS Med

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    March 2021
  1. LEONG A, Cole JB, Brenner LN, Meigs JB, et al
    Cardiometabolic risk factors for COVID-19 susceptibility and severity: A Mendelian randomization analysis.
    PLoS Med. 2021;18:e1003553.
    PubMed     Abstract available


    February 2021
  2. MANOUSAKI D, Harroud A, Mitchell RE, Ross S, et al
    Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study.
    PLoS Med. 2021;18:e1003536.
    PubMed     Abstract available


    December 2020
  3. NEUENSCHWANDER M, Barbaresko J, Pischke CR, Iser N, et al
    Intake of dietary fats and fatty acids and the incidence of type 2 diabetes: A systematic review and dose-response meta-analysis of prospective observational studies.
    PLoS Med. 2020;17:e1003347.
    PubMed     Abstract available


  4. YUN H, Sun L, Wu Q, Zong G, et al
    Associations among circulating sphingolipids, beta-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China.
    PLoS Med. 2020;17:e1003451.
    PubMed     Abstract available


  5. MCGLONE ER, Carey I, Velickovic V, Chana P, et al
    Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses.
    PLoS Med. 2020;17:e1003228.
    PubMed     Abstract available


  6. MUSSO G, Sircana A, Saba F, Cassader M, et al
    Assessing the risk of ketoacidosis due to sodium-glucose cotransporter (SGLT)-2 inhibitors in patients with type 1 diabetes: A meta-analysis and meta-regression.
    PLoS Med. 2020;17:e1003461.
    PubMed     Abstract available


    November 2020
  7. FLOOD D, Hane J, Dunn M, Brown SJ, et al
    Health system interventions for adults with type 2 diabetes in low- and middle-income countries: A systematic review and meta-analysis.
    PLoS Med. 2020;17:e1003434.
    PubMed     Abstract available


  8. ALI KHAN U, Fallah M, Sundquist K, Sundquist J, et al
    Risk of colorectal cancer in patients with diabetes mellitus: A Swedish nationwide cohort study.
    PLoS Med. 2020;17:e1003431.
    PubMed     Abstract available


  9. MORDI IR, Chan BK, Yanez ND, Palmer CNA, et al
    Genetic and pharmacological relationship between P-glycoprotein and increased cardiovascular risk associated with clarithromycin prescription: An epidemiological and genomic population-based cohort study in Scotland, UK.
    PLoS Med. 2020;17:e1003372.
    PubMed     Abstract available


  10. PELL D, Penney TL, Mytton O, Briggs A, et al
    Anticipatory changes in British household purchases of soft drinks associated with the announcement of the Soft Drinks Industry Levy: A controlled interrupted time series analysis.
    PLoS Med. 2020;17:e1003269.
    PubMed     Abstract available


  11. ANTOUN E, Kitaba NT, Titcombe P, Dalrymple KV, et al
    Maternal dysglycaemia, changes in the infant's epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial.
    PLoS Med. 2020;17:e1003229.
    PubMed     Abstract available


  12. AYRE J, Cvejic E, Bonner C, Turner RM, et al
    Effects of health literacy, screening, and participant choice on action plans for reducing unhealthy snacking in Australia: A randomised controlled trial.
    PLoS Med. 2020;17:e1003409.
    PubMed     Abstract available


    October 2020
  13. LIM LL, Lau ESH, Ozaki R, Chung H, et al
    Association of technologically assisted integrated care with clinical outcomes in type 2 diabetes in Hong Kong using the prospective JADE Program: A retrospective cohort analysis.
    PLoS Med. 2020;17:e1003367.
    PubMed     Abstract available


  14. ZHENG JS, Luan J, Sofianopoulou E, Sharp SJ, et al
    The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.
    PLoS Med. 2020;17:e1003394.
    PubMed     Abstract available


  15. CAPTIEUX M, Prigge R, Wild S, Guthrie B, et al
    Defining remission of type 2 diabetes in research studies: A systematic scoping review.
    PLoS Med. 2020;17:e1003396.
    PubMed     Abstract available


  16. MORAITIS AA, Shreeve N, Sovio U, Brocklehurst P, et al
    Universal third-trimester ultrasonic screening using fetal macrosomia in the prediction of adverse perinatal outcome: A systematic review and meta-analysis of diagnostic test accuracy.
    PLoS Med. 2020;17:e1003190.
    PubMed     Abstract available


    September 2020
  17. KE C, Stukel TA, Shah BR, Lau E, et al
    Age at diagnosis, glycemic trajectories, and responses to oral glucose-lowering drugs in type 2 diabetes in Hong Kong: A population-based observational study.
    PLoS Med. 2020;17:e1003316.
    PubMed     Abstract available


  18. HARRISON SL, Fazio-Eynullayeva E, Lane DA, Underhill P, et al
    Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis.
    PLoS Med. 2020;17:e1003321.
    PubMed     Abstract available


    August 2020
  19. WILKINSON L, Yi N, Mehta T, Judd S, et al
    Development and validation of a model for predicting incident type 2 diabetes using quantitative clinical data and a Bayesian logistic model: A nationwide cohort and modeling study.
    PLoS Med. 2020;17:e1003232.
    PubMed     Abstract available


  20. ENGEDA JC, Lhachimi SK, Rosamond WD, Lund JL, et al
    Projections of incident atherosclerotic cardiovascular disease and incident type 2 diabetes across evolving statin treatment guidelines and recommendations: A modelling study.
    PLoS Med. 2020;17:e1003280.
    PubMed     Abstract available


  21. CHEN J, Bacelis J, Sole-Navais P, Srivastava A, et al
    Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother-infant pairs.
    PLoS Med. 2020;17:e1003305.
    PubMed     Abstract available


    July 2020
  22. JIANG G, Luk AO, Tam CHT, Lau ES, et al
    Obesity, clinical, and genetic predictors for glycemic progression in Chinese patients with type 2 diabetes: A cohort study using the Hong Kong Diabetes Register and Hong Kong Diabetes Biobank.
    PLoS Med. 2020;17:e1003209.
    PubMed     Abstract available


  23. SALGADO MV, Penko J, Fernandez A, Konfino J, et al
    Projected impact of a reduction in sugar-sweetened beverage consumption on diabetes and cardiovascular disease in Argentina: A modeling study.
    PLoS Med. 2020;17:e1003224.
    PubMed     Abstract available


  24. WIGGINS T, Guidozzi N, Welbourn R, Ahmed AR, et al
    Association of bariatric surgery with all-cause mortality and incidence of obesity-related disease at a population level: A systematic review and meta-analysis.
    PLoS Med. 2020;17:e1003206.
    PubMed     Abstract available


    June 2020
  25. IMAMURA F, Fretts AM, Marklund M, Ardisson Korat AV, et al
    Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.
    PLoS Med. 2020;17:e1003102.
    PubMed     Abstract available


  26. ATABAKI-PASDAR N, Ohlsson M, Vinuela A, Frau F, et al
    Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts.
    PLoS Med. 2020;17:e1003149.
    PubMed     Abstract available


    May 2020
  27. CHIANG JI, Hanlon P, Li TC, Jani BD, et al
    Multimorbidity, mortality, and HbA1c in type 2 diabetes: A cohort study with UK and Taiwanese cohorts.
    PLoS Med. 2020;17:e1003094.
    PubMed     Abstract available


  28. MATHUR R, Farmer RE, Eastwood SV, Chaturvedi N, et al
    Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990-2017: A cohort study.
    PLoS Med. 2020;17:e1003106.
    PubMed     Abstract available


  29. LAI M, Liu Y, Ronnett GV, Wu A, et al
    Amino acid and lipid metabolism in post-gestational diabetes and progression to type 2 diabetes: A metabolic profiling study.
    PLoS Med. 2020;17:e1003112.
    PubMed     Abstract available


  30. TARRY-ADKINS JL, Aiken CE, Ozanne SE
    Comparative impact of pharmacological treatments for gestational diabetes on neonatal anthropometry independent of maternal glycaemic control: A systematic review and meta-analysis.
    PLoS Med. 2020;17:e1003126.
    PubMed     Abstract available


  31. KUMAR GS, Wien SS, Phares CR, Slim W, et al
    Health profile of adult special immigrant visa holders arriving from Iraq and Afghanistan to the United States, 2009-2017: A cross-sectional analysis.
    PLoS Med. 2020;17:e1003118.
    PubMed     Abstract available


    March 2020
  32. REYNOLDS AN, Akerman AP, Mann J
    Dietary fibre and whole grains in diabetes management: Systematic review and meta-analyses.
    PLoS Med. 2020;17:e1003053.
    PubMed     Abstract available


  33. LUND-BLIX NA, Tapia G, Marild K, Brantsaeter AL, et al
    Maternal and child gluten intake and association with type 1 diabetes: The Norwegian Mother and Child Cohort Study.
    PLoS Med. 2020;17:e1003032.
    PubMed     Abstract available


    February 2020
  34. LUK AOY, Ke C, Lau ESH, Wu H, et al
    Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study.
    PLoS Med. 2020;17:e1003052.
    PubMed     Abstract available


  35. WILLIS TA, Collinson M, Glidewell L, Farrin AJ, et al
    An adaptable implementation package targeting evidence-based indicators in primary care: A pragmatic cluster-randomised evaluation.
    PLoS Med. 2020;17:e1003045.
    PubMed     Abstract available


    January 2020
  36. CHENG TS, Day FR, Lakshman R, Ong KK, et al
    Association of puberty timing with type 2 diabetes: A systematic review and meta-analysis.
    PLoS Med. 2020;17:e1003017.
    PubMed     Abstract available


    December 2019
  37. WAINBERG M, Mahajan A, Kundaje A, McCarthy MI, et al
    Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study.
    PLoS Med. 2019;16:e1002982.
    PubMed     Abstract available


  38. FOLAND-ROSS LC, Buckingam B, Mauras N, Arbelaez AM, et al
    Executive task-based brain function in children with type 1 diabetes: An observational study.
    PLoS Med. 2019;16:e1002979.
    PubMed     Abstract available


  39. WONG CKH, Man KKC, Shi M, Chan EW, et al
    Intensification with dipeptidyl peptidase-4 inhibitor, insulin, or thiazolidinediones and risks of all-cause mortality, cardiovascular diseases, and severe hypoglycemia in patients on metformin-sulfonylurea dual therapy: A retrospective cohort study.
    PLoS Med. 2019;16:e1002999.
    PubMed     Abstract available


  40. JARDIM TV, Mozaffarian D, Abrahams-Gessel S, Sy S, et al
    Cardiometabolic disease costs associated with suboptimal diet in the United States: A cost analysis based on a microsimulation model.
    PLoS Med. 2019;16:e1002981.
    PubMed     Abstract available


  41. MENNE J, Dumann E, Haller H, Schmidt BMW, et al
    Acute kidney injury and adverse renal events in patients receiving SGLT2-inhibitors: A systematic review and meta-analysis.
    PLoS Med. 2019;16:e1002983.
    PubMed     Abstract available


  42. AHLQVIST VH, Persson M, Magnusson C, Berglind D, et al
    Elective and nonelective cesarean section and obesity among young adult male offspring: A Swedish population-based cohort study.
    PLoS Med. 2019;16:e1002996.
    PubMed     Abstract available


    November 2019
  43. JANS A, Naslund I, Ottosson J, Szabo E, et al
    Duration of type 2 diabetes and remission rates after bariatric surgery in Sweden 2007-2015: A registry-based cohort study.
    PLoS Med. 2019;16:e1002985.
    PubMed     Abstract available


    October 2019
  44. WEI Y, Xu Q, Yang H, Yang Y, et al
    Preconception diabetes mellitus and adverse pregnancy outcomes in over 6.4 million women: A population-based cohort study in China.
    PLoS Med. 2019;16:e1002926.
    PubMed     Abstract available


  45. WHYTE MB, Hinton W, McGovern A, van Vlymen J, et al
    Disparities in glycaemic control, monitoring, and treatment of type 2 diabetes in England: A retrospective cohort analysis.
    PLoS Med. 2019;16:e1002942.
    PubMed     Abstract available


  46. OCHS A, McGurnaghan S, Black MW, Leese GP, et al
    Use of personalised risk-based screening schedules to optimise workload and sojourn time in screening programmes for diabetic retinopathy: A retrospective cohort study.
    PLoS Med. 2019;16:e1002945.
    PubMed     Abstract available


  47. NG NYH, Jiang G, Cheung LP, Zhang Y, et al
    Progression of glucose intolerance and cardiometabolic risk factors over a decade in Chinese women with polycystic ovary syndrome: A case-control study.
    PLoS Med. 2019;16:e1002953.
    PubMed     Abstract available


    September 2019
  48. ZHU Y, Li M, Rahman ML, Hinkle SN, et al
    Plasma phospholipid n-3 and n-6 polyunsaturated fatty acids in relation to cardiometabolic markers and gestational diabetes: A longitudinal study within the prospective NICHD Fetal Growth Studies.
    PLoS Med. 2019;16:e1002910.
    PubMed     Abstract available


  49. RUSCITTI P, Masedu F, Alvaro S, Airo P, et al
    Anti-interleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial.
    PLoS Med. 2019;16:e1002901.
    PubMed     Abstract available


  50. CHIVESE T, Norris SA, Levitt NS
    Progression to type 2 diabetes mellitus and associated risk factors after hyperglycemia first detected in pregnancy: A cross-sectional study in Cape Town, South Africa.
    PLoS Med. 2019;16:e1002865.
    PubMed     Abstract available


    August 2019
  51. TARRY-ADKINS JL, Aiken CE, Ozanne SE
    Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: A systematic review and meta-analysis.
    PLoS Med. 2019;16:e1002848.
    PubMed     Abstract available


    July 2019
  52. DALY B, Toulis KA, Thomas N, Gokhale K, et al
    Correction: Increased risk of ischemic heart disease, hypertension, and type 2 diabetes in women with previous gestational diabetes mellitus, a target group in general practice for preventive interventions: A population-based cohort study.
    PLoS Med. 2019;16:e1002881.
    PubMed     Abstract available


  53. LIPNICKI DM, Makkar SR, Crawford JD, Thalamuthu A, et al
    Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study.
    PLoS Med. 2019;16:e1002853.
    PubMed     Abstract available


  54. H AL WATTAR B, Dodds J, Placzek A, Beresford L, et al
    Mediterranean-style diet in pregnant women with metabolic risk factors (ESTEEM): A pragmatic multicentre randomised trial.
    PLoS Med. 2019;16:e1002857.
    PubMed     Abstract available


    March 2019
  55. MANNE-GOEHLER J, Geldsetzer P, Agoudavi K, Andall-Brereton G, et al
    Health system performance for people with diabetes in 28 low- and middle-income countries: A cross-sectional study of nationally representative surveys.
    PLoS Med. 2019;16:e1002751.
    PubMed     Abstract available


    January 2019
  56. BLAKELY T, Kvizhinadze G, Atkinson J, Dieleman J, et al
    Health system costs for individual and comorbid noncommunicable diseases: An analysis of publicly funded health events from New Zealand.
    PLoS Med. 2019;16:e1002716.
    PubMed     Abstract available


  57. JOHANSSON M, Carreras-Torres R, Scelo G, Purdue MP, et al
    The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study.
    PLoS Med. 2019;16:e1002724.
    PubMed     Abstract available


    October 2018
  58. IMAMURA F, Fretts A, Marklund M, Ardisson Korat AV, et al
    Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.
    PLoS Med. 2018;15:e1002670.
    PubMed     Abstract available


  59. GOMES D, von Kries R, Delius M, Mansmann U, et al
    Late-pregnancy dysglycemia in obese pregnancies after negative testing for gestational diabetes and risk of future childhood overweight: An interim analysis from a longitudinal mother-child cohort study.
    PLoS Med. 2018;15:e1002681.
    PubMed     Abstract available


    September 2018
  60. UDLER MS, Kim J, von Grotthuss M, Bonas-Guarch S, et al
    Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.
    PLoS Med. 2018;15:e1002654.
    PubMed     Abstract available


    August 2018
  61. FENG Q, Wei WQ, Chung CP, Levinson RT, et al
    Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records.
    PLoS Med. 2018;15:e1002642.
    PubMed     Abstract available


    July 2018
  62. LAM HCY, Chan JCN, Luk AOY, Chan EYY, et al
    Short-term association between ambient temperature and acute myocardial infarction hospitalizations for diabetes mellitus patients: A time series study.
    PLoS Med. 2018;15:e1002612.
    PubMed     Abstract available


    June 2018
  63. THANKAPPAN KR, Sathish T, Tapp RJ, Shaw JE, et al
    A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program.
    PLoS Med. 2018;15:e1002575.
    PubMed     Abstract available


    May 2018
  64. LU L, Bennett DA, Millwood IY, Parish S, et al
    Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.
    PLoS Med. 2018;15:e1002566.
    PubMed     Abstract available


    April 2018
  65. BONIFACIO E, Beyerlein A, Hippich M, Winkler C, et al
    Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.
    PLoS Med. 2018;15:e1002548.
    PubMed     Abstract available


    March 2018
  66. XU X, Mishra GD, Dobson AJ, Jones M, et al
    Progression of diabetes, heart disease, and stroke multimorbidity in middle-aged women: A 20-year cohort study.
    PLoS Med. 2018;15:e1002516.
    PubMed     Abstract available


    January 2018
  67. DALY B, Toulis KA, Thomas N, Gokhale K, et al
    Increased risk of ischemic heart disease, hypertension, and type 2 diabetes in women with previous gestational diabetes mellitus, a target group in general practice for preventive interventions: A population-based cohort study.
    PLoS Med. 2018;15:e1002488.
    PubMed     Abstract available


    October 2017
  68. IMAMURA F, Sharp SJ, Koulman A, Schulze MB, et al
    A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study.
    PLoS Med. 2017;14:e1002409.
    PubMed     Abstract available


  69. MA RCW, Popkin BM
    Intergenerational diabetes and obesity-A cycle to break?
    PLoS Med. 2017;14:e1002415.
    PubMed     Abstract available


    September 2017
  70. WHEELER E, Leong A, Liu CT, Hivert MF, et al
    Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
    PLoS Med. 2017;14:e1002383.
    PubMed     Abstract available


  71. PATERSON AD
    HbA1c for type 2 diabetes diagnosis in Africans and African Americans: Personalized medicine NOW!
    PLoS Med. 2017;14:e1002384.
    PubMed     Abstract available


  72. PATEL SA, Dhillon PK, Kondal D, Jeemon P, et al
    Chronic disease concordance within Indian households: A cross-sectional study.
    PLoS Med. 2017;14:e1002395.
    PubMed     Abstract available


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